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Journal of Dermatology

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https://www.readbyqxmd.com/read/27917531/burden-of-herpes-zoster-and-postherpetic-neuralgia-in-japanese-adults-60-years-of-age-or-older-results-from-an-observational-prospective-physician-practice-based-cohort-study
#1
Keiko Sato, Koichi Adachi, Hiroyuki Nakamura, Kazuhiro Asano, Akihiro Watanabe, Riri Adachi, Mariko Kiuchi, Keiju Kobayashi, Taizo Matsuki, Toshihiko Kaise, Kusuma Gopala, Katsiaryna Holl
Approximately one in three persons will develop herpes zoster during their lifetime, and it can lead to serious complications such as postherpetic neuralgia. However, evidence on burden of herpes zoster and postherpetic neuralgia in Japan is limited. This prospective, observational, multicenter, physician practice-based cohort study was conducted in Kushiro, Hokkaido, Japan (Clinicaltrials.gov identifier NCT01873365) to assess the incidence and hospitalization rates of herpes zoster, and the proportion, clinical burden and risk factors for postherpetic neuralgia in adults aged 60 years or more...
December 5, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27914108/diagnostic-usefulness-of-dermoscopy-in-differentiating-lichen-aureus-from-nummular-eczema
#2
Kee Suck Suh, Jong Bin Park, Myeong Hyeon Yang, Soo Young Choi, Hyun Hwangbo, Min Soo Jang
Lichen aureus (LA) is a variant of pigmented purpuric dermatosis that is characterized clinically by rust macules, papules or plaques, mainly on the legs. In some cases, LA can be difficult to be distinguished from nummular eczema (NE) with the naked eye. Dermoscopy can be applied to skin lesions, revealing additional features that can be highly valuable for correct diagnosis. This study was conducted to investigate characteristic dermoscopic findings of LA and to identify distinctive features that can differentiate it from NE...
December 3, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27914107/non-paraneoplastic-autoimmune-subepidermal-bullous-disease-associated-with-fatal-bronchiolitis-obliterans
#3
Mari Orime, Katsuhiro Tomiyama, Hideki Hashidate, Satoru Yoshida, Satoshi Hokari, Akiko Tsuda, Hisashi Yokoyama, Jun-Ichi Narita, Youhei Uchida, Takuro Kanekura, Riichiro Abe, Norito Ishii, Takashi Hashimoto, Kazuhiro Kawai
Bronchiolitis obliterans is a small-airway obstructive lung disease for which immunologically mediated pathogenesis is supposed. Frequent association of bronchiolitis obliterans with paraneoplastic pemphigus is well known, but its association with other autoimmune bullous diseases has not been reported except for a case of anti-laminin-332-type mucous membrane pemphigoid in a patient with chronic graft-versus-host disease. We report a case of non-paraneoplastic autoimmune subepidermal bullous disease associated with fatal bronchiolitis obliterans in a patient without transplantation...
December 3, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27914096/successful-treatment-of-multiple-in-transit-melanomas-on-the-leg-with-intensity-modulated-radiotherapy-and-immune-checkpoint-inhibitors-report-of-two-cases
#4
Taku Fujimura, Yumi Kambayashi, Sadanori Furudate, Takanori Hidaka, Yota Sato, Kayo Tanita, Hisayuki Tono, Akira Tsukada, Akira Hashimoto, Setsuya Aiba
Because the efficacy rates of monotherapy with immune checkpoint inhibitors such as nivolumab or ipilimumab are not sufficient, to enhance the antitumor effects of these reagents is of great interest among dermato-oncologists. In this report, we describe two cases of multiple in-transit metastatic melanomas on the leg successfully treated with intensity-modulated radiotherapy (IMRT) using a CyberKnife in combination with ipilimumab or nivolumab. Our cases suggested that IMRT could enhance the antitumor effects of immune checkpoint inhibitors in patients with multiple in-transit melanomas...
December 3, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27914095/pyodermatitis-vegetans-with-antibodies-to-bullous-pemphigoid-antigen-180
#5
LETTER
Hisao Kawahira, Yuko Higashi, Atsuko Matsuoka, Kazuyasu Fujii, Norito Ishii, Takashi Hashimoto, Takuro Kanekura
No abstract text is available yet for this article.
December 3, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27882601/case-of-pigmented-epithelioid-melanocytoma-affecting-the-thumbnail
#6
LETTER
Dai Ogata, Eiichi Arai, Masahito Taguchi, Kuniaki Ohara, Toshiaki Saida, Tetsuya Tsuchida
No abstract text is available yet for this article.
November 24, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27882598/kaposi-s-varicelliform-eruption-presenting-with-extensive-skin-lesions-and-sepsis
#7
LETTER
Mizue Fujii, Ichiro Takahashi, Masaru Honma, Akemi Ishida-Yamamoto
No abstract text is available yet for this article.
November 24, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27882597/morphological-analyses-in-fragility-of-pili-torti-with-bj%C3%A3-rnstad-syndrome
#8
Yuki Marubashi, Takeshi Yanagishita, Jun Muto, Nobuhiko Taguchi, Kazumitsu Sugiura, Yoshiyuki Kawamoto, Masashi Akiyama, Daisuke Watanabe
Pili torti is an extremely rare hair phenotype characterized by short length of hairs with hair shafts being easily broken. However, the mechanism of fragility in pili torti is unclear. In this study, we examined the underlying morphological features responsible for pili torti formation using transmission electron microscopy (TEM). We used pili torti samples from a patient with Björnstad syndrome and normal hairs from a healthy subject as a comparison. The macroscopic morphological features of the samples agreed with the results of a previous study showing that pili torti is twisted, flattened, thin and with partial trichorrhexis...
November 24, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27882591/more-than-a-coincidence-cholesterol-crystal-embolization-in-the-unaffected-abdominal-skin
#9
LETTER
Naoya Murayama, Saori Tomimura, Sayaka Kuwatsuka, Yumi Okubo, Satoshi Ikeda, Atsushi Utani
No abstract text is available yet for this article.
November 24, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27882590/non-pigmented-basal-cell-carcinoma-occurring-within-a-widespread-vitiliginous-lesion
#10
LETTER
Shohei Igari, Tomoko Hiraiwa, Nobuyuki Kikuchi, Yuka Hanami, Masataka Satoh, Toshiyuki Yamamoto
No abstract text is available yet for this article.
November 24, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27882588/clinical-and-epidemiological-analysis-in-149-cases-of-rhododendrol-induced-leukoderma
#11
Momoko Yoshikawa, Yasuyuki Sumikawa, Tokimasa Hida, Takafumi Kamiya, Kimi Kase, Yasue Ishii-Osai, Junji Kato, Yuji Kan, Shiori Kamiya, Yuki Sato, Toshiharu Yamashita
Rhododendrol-induced leukoderma is an acquired depigmentation that develops mainly at the contact site after repeated use of skin-whitening cosmetics containing rhododendrol. In most cases, cessation of further depigmentation or occurrence of repigmentation is observed after discontinuing the use of cosmetics. However, some patients develop vitiligo vulgaris through the spread of depigmentation into the non-exposed areas. Our study aims to investigate the patient-specific factors that may affect the extent of depigmentation or repigmentation, as well as development of vitiligo vulgaris...
November 24, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27882586/efficacy-and-safety-of-dose-escalation-of-infliximab-therapy-in-japanese-patients-with-psoriasis-results-of-the-spread-study
#12
Hideshi Torii, Masayuki Nakano, Toshiro Yano, Kazuoki Kondo, Hidemi Nakagawa
Although infliximab is approved for psoriasis, its efficacy is reduced over time in some patients. The aim of this phase III trial is to evaluate efficacy and safety of infliximab dose escalation in Japanese psoriasis patients with loss of efficacy to standard-dose therapy. Patients with plaque psoriasis, psoriatic arthritis, pustular psoriasis or psoriatic erythroderma who showed loss of efficacy to standard-dose therapy received infliximab dose escalation (10 mg/kg every 8 weeks) from weeks 0 to 32. Loss of efficacy was defined as not maintaining 50% reduction in the Psoriasis Area and Severity Index (PASI 50) after achieving PASI 75...
November 24, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27882581/achieved-good-response-of-s-1-and-docetaxel-combination-chemotherapy-in-two-patients-with-metastatic-extramammary-paget-s-disease
#13
LETTER
Sho Egashira, Ikko Kajihara, Hisashi Kanemaru, Mihoko Uemura-Kiyohara, Saori Yamada-Kanazawa, Satoshi Nakahara, Eiko Nagamoto, Satoshi Fukushima, Masatoshi Jinnin, Yuji Inoue, Hironobu Ihn
No abstract text is available yet for this article.
November 24, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27864844/pyogenic-granuloma-possibly-associated-with-capecitabine-therapy
#14
LETTER
Chisako Fujiwara, Sei-Ichiro Motegi, Akiko Sekiguchi, Hiroo Amano, Osamu Ishikawa
No abstract text is available yet for this article.
November 18, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27864842/elevation-of-serum-carcinoembryonic-antigen-in-a-case-of-cholinergic-urticaria-with-failed-detection-of-hypohidrosis-by-the-conventional-starch-iodine-test
#15
LETTER
Masaru Honma, Hiroyoshi Nozaki, Hiroko Nagahata, Mizue Fujii, Kyoko Kanno, Masako Minami-Hori, Akemi Ishida-Yamamoto
No abstract text is available yet for this article.
November 18, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27864841/clinical-factors-predicting-the-therapeutic-response-to-ustekinumab-in-patients-with-moderate-to-severe-chronic-plaque-psoriasis
#16
Young Ji Hwang, Sang Woong Youn, Bo Ri Kim, Dae Young Yu, Youngdoe Kim, Antonio Pires, Soyun Cho, Seong Jun Seo, Eun So Lee, Joo Young Roh, Gwang Seong Choi, Min Geol Lee
While ustekinumab has been widely used as an effective biologic for the treatment of chronic plaque psoriasis, no prospective studies have specifically investigated the clinical factors that may influence treatment outcomes with ustekinumab. This post-hoc analysis aimed to identify specific clinical factors that may influence treatment outcomes with ustekinumab in psoriasis patients. In the MARCOPOLO study, 102 Korean patients with moderate to severe psoriasis were analyzed to assess the influence of baseline characteristics as clinical factors on clinical response (improvement in Psoriasis Area and Severity Index by ≥75%/90% [PASI75/PASI90]) to ustekinumab...
November 18, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27864840/ectopic-respiratory-mucosa-in-the-skin-which-showed-the-repetitive-distribution-of-ciliated-bronchogenic-epithelia-and-squamous-metaplasia
#17
LETTER
Naomi Nakano, Takeo Nakaya, Koji Kamiya, Mayumi Komine, Satoru Murata, Hirotoshi Kawata, Shigeo Yokoyama, Akira Tanaka, Mamitaro Ohtsuki
No abstract text is available yet for this article.
November 18, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27864834/case-of-metastatic-uveal-melanoma-in-which-an-antitumor-effect-appeared-after-ipilimumab-discontinuation-due-to-autoimmune-hypophysitis
#18
LETTER
Takehiro Ohnuma, Takamitsu Matsuzawa, Manao Kinoshita, Shinya Sano, Tatsuyoshi Kawamura, Shinji Shimada, Takashi Inozume
No abstract text is available yet for this article.
November 18, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27864829/pediatric-case-of-anaplastic-lymphoma-kinase-positive-anaplastic-large-cell-lymphoma-forming-a-solitary-skin-tumor-on-the-forearm
#19
Michio Tokuyama, Yuta Kurashige, Tami Ota, Yasuaki Manabe, Hanako Yamaoka, Norihiro Ikoma, Akiko Fukumura, Michie Miyashita, Keisuke Otsubo, Tsuyoshi Morimoto, Hiroyuki Mochizuki, Natsuko Nakano, Naoya Nakamura, Akira Ozawa, Tomotaka Mabuchi
A 5-year-old girl noticed a rapidly growing reddish nodule on her right forearm. Although oral antibiotics had been administrated for 2 weeks, the tumor enlarged. Skin biopsy revealed excessive infiltration of atypical neoplastic cells expressing CD4, CD30 and anaplastic lymphoma kinase (ALK). These histological and immunohistochemical findings were consistent with anaplastic large cell lymphoma (ALCL). Computed tomography showed multiple lymphadenopathy, but lymph node biopsy and bone marrow examination did not show any evidence of systemic dissemination...
November 18, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27864824/successful-treatment-of-ustekinumab-in-a-psoriasis-patient-with-human-t-cell-leukemia-lymphotropic-virus-type-1-infection
#20
LETTER
Mariko Kazama, Yoshinori Umezawa, Munenari Itoh, Yoshimasa Nobeyama, Toshihiro Ito, Sota Kikuchi, Koichi Yanaba, Akihiko Asahina, Hidemi Nakagawa, Yoji Ogasawara
No abstract text is available yet for this article.
November 18, 2016: Journal of Dermatology
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