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Journal of Dermatology

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https://www.readbyqxmd.com/read/28332728/keratoacanthoma-en-plaque-nodule-a-brief-report-of-the-clinicopathological-features-of-five-cases
#1
Noriyuki Misago, Shin-Ichi Ansai, Takaya Fukumoto, Takashi Anan, Tomokazu Nakao
Keratoacanthoma (KA) is characterized by exoendophytic growth with a central keratin-filled crater, representing the crateriform architecture. We herein report five rare cases of KA without a central keratin-filled crater. These KA cases histopathologically showed that one or a few infundibular structures/isthmic lobules had their own open keratotic pores on the surface without a common merged keratotic plug/horn, clinically representing verrucous (keratotic) plaque/nodule, namely, "KA en plaque/nodule". KA rarely but on occasion does show verrucous plaque (or nodular) lesions without a central keratin-filled crater, as the notion that KA invariably shows crateriform architecture is nonsensical...
March 23, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28332722/translucent-basal-cell-carcinoma-with-a-single-cyst-of-the-upper-eyelid
#2
LETTER
Ayumi Korekawa, Koji Nakajima, Hajime Nakano, Daisuke Sawamura
No abstract text is available yet for this article.
March 23, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28332720/efficacy-and-safety-of-luliconazole-5-nail-solution-for-the-treatment-of-onychomycosis-a-multicenter-double-blind-randomized-phase-iii-study
#3
Shinichi Watanabe, Hiroshi Kishida, Akihiro Okubo
Onychomycosis is a highly prevalent and intractable disease. The first-line treatment agents are oral preparations, but an effective topical medication has long been desired. The objective was to investigate the efficacy and safety of luliconazole 5% nail solution, an imidazole antifungal agent, for the treatment of patients with onychomycosis. A multicenter, double-blind, randomized phase III study was conducted in Japanese patients with distal lateral subungual onychomycosis affecting the great toenails, with 20-50% clinical involvement...
March 23, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28328114/diagnosis-of-pseudoxanthoma-elasticum-in-a-4-year-old-boy
#4
LETTER
Nobuki Maki, Mayumi Komine, Hidetoshi Tsuda, Yurika Fujita, Etsuko Fujita, Satoru Murata, Toshio Demitsu, Atsushi Utani, Mamitaro Ohtsuki
No abstract text is available yet for this article.
March 22, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28328104/atypical-case-of-merkel-cell-carcinoma-difficult-to-diagnose-clinically
#5
LETTER
Yuri Kinoshita, Toshihiko Hoashi, Shizuka Okazaki, Kasho Kataoka, Toshie Nako, Nobuko Mayumi, Takeshi Kouno, Yoko Funasaka, Shin-Ichi Ansai, Hidehisa Saeki
No abstract text is available yet for this article.
March 22, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28328088/evaluation-of-the-correlation-between-severity-of-acquired-idiopathic-generalized-anhidrosis-and-quality-of-life-scores
#6
Takichi Munetsugu, Tomoko Fujimoto, Takahiro Satoh, Yoshihiko Nakazato, Yuichiro Ohshima, Masato Asahina, Hiroo Yokozeki
Symptoms of acquired idiopathic generalized anhidrosis (AIGA) include heat retention and/or heat stroke due to the effects of the disorder on the perspiration ability of the whole body under thermal environmental changes or exercise. Additionally, cholinergic urticaria can also occur in these patients. AIGA has a major impact on everyday life. However, the effects of AIGA severity on the quality of life (QOL) of the patients have not been sufficiently defined. The objective of this study was to evaluate the correlation between AIGA severity and QOL...
March 22, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28326616/high-prevalence-of-sensitization-to-gibberellin-regulated-protein-peamaclein-in-fruit-allergies-with-negative-immunoglobulin-e-reactivity-to-bet-v-1-homologs-and-profilin-clinical-pattern-causative-fruits-and-cofactor-effect-of-gibberellin-regulated-protein
#7
Naoko Inomata, Mami Miyakawa, Michiko Aihara
Gibberellin-regulated protein (GRP) is a new allergen in peach allergy, with an amino acid sequence very well conserved through several botanical species. We investigated the allergenicity of GRP in fruit allergies other than peaches and identified the clinical characteristics of fruit allergy patients with GRP sensitization. One hundred consecutive Japanese patients with fruit allergies were enrolled in the present study. To identify the features of GRP sensitization, we selected patients with negative ImmunoCAP results for Bet v 1 homologs and profilin, which are marker allergens for pollen-food allergy syndrome (PFAS), or lipid transfer protein...
March 22, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28326613/a-first-case-of-tick-bite-by-amblyomma-coelebs-in-japan
#8
LETTER
Kazuaki Ito, Hiroko Taniguchi, Noriko Ohtaki, Shuji Ando, Hiroki Kawabata
No abstract text is available yet for this article.
March 22, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28295566/concomitant-confluent-and-reticulated-papillomatosis-and-acanthosis-nigricans-in-an-obese-girl-with-insulin-resistance-successfully-treated-with-oral-minocycline-case-report-and-published-work-review
#9
Takeshi Fukumoto, Takeshi Kozaru, Masanobu Sakaguchi, Masahiro Oka
Concomitant confluent and reticulated papillomatosis (CRP) and acanthosis nigricans (AN) is rare. We present a case of concomitant CRP and obesity-associated AN in a 12-year-old obese Japanese girl. Curiously, oral minocycline therapy, which has been shown to be effective for CRP, was effective against both CRP and AN. Possible mechanisms by which minocycline could have improved skin lesions of CRP and obesity-associated AN are discussed. In addition, reports of concomitant CRP and obesity-associated AN are reviewed...
March 11, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28295564/neutrophils-are-not-the-dominant-interleukin-17-producer-in-psoriasis
#10
LETTER
Keiichi Yamanaka, Akisa Yamagiwa, Tomoko Akeda, Makoto Kondo, Masato Kakeda, Koji Habe, Shinichi Imafuku, Shigetoshi Sano, Hitoshi Mizutani
No abstract text is available yet for this article.
March 11, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28295558/somatic-hras-p-g12s-mosaic-mutation-causes-unilaterally-distributed-epidermal-nevi-woolly-hair-and-palmoplantar-keratosis
#11
LETTER
Aki Honda, Noriko Umegaki-Arao, Takashi Sasaki, Kazuhiko Nakabayashi, Kenichiro Hata, Yoichi Matsubara, Akiko Tanikawa, Masayuki Amagai, Akiharu Kubo
No abstract text is available yet for this article.
March 11, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28295555/evaluation-of-positron-emission-tomography-imaging-to-detect-lymph-node-metastases-in-patients-with-extramammary-paget-s-disease
#12
Masao Fujiwara, Takahiro Suzuki, Ayumi Senoo, Hidekazu Fukamizu, Yoshiki Tokura
Patients with extramammary Paget's disease (EMPD) have a relatively good prognosis, when spread of the tumor cells is limited to the epidermis. However, invasive EMPD has a poor prognosis, when the patients have regional lymph node metastasis. Detection of nodal metastasis is thus mandatory to manage EMPD. To evaluate the (18) F-fluorodeoxyglucose positron emission tomography (FDG-PET) imaging to assess lymph node metastasis, 15 patients with histologically proven primary EMPD were enrolled in this study. All patients underwent whole-body PET prior to sentinel lymph node biopsy (SLNB)...
March 11, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28295553/serum-carcinoembryonic-antigen-specifically-increases-among-various-serum-markers-of-adenocarcinoma-in-hypohidrosis-or-conditions-related-to-hypohidrosis
#13
Masaru Honma, Hiroyoshi Nozaki, Hiroko Nagahata, Mizue Fujii, Takashi Shibuya, Kyoko Kanno, Masako Minami-Hori, Akemi Ishida-Yamamoto
Anhidrosis/hypohidrosis are conditions presenting various level of sweating dysfunction. Among them, acquired idiopathic generalized anhidrosis (AIGA) presents inadequate decrease or loss of sweating without apparent neurological and dermatological symptoms except cholinergic urticaria. Recently, serum level of carcinoembryonic antigen (CEA), one of the most well-known tumor markers, has been proposed as a clinical marker reflecting activity of AIGA. This study was performed to verify the specificity and independence of serum CEA level from the other serum tumor markers especially related to adenocarcinoma...
March 11, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28295551/hypopituitarism-and-hypothyroidism-following-atrioventricular-block-during-nivolumab-treatment
#14
LETTER
Tomoko Oda, Yu Sawada, Etsuko Okada, Takashi Yamaguchi, Shun Ohmori, Sanehito Haruyama, Manabu Yoshioka, Motonobu Nakamura
No abstract text is available yet for this article.
March 11, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28295545/successful-propranolol-treatment-for-diffuse-neonatal-hemangiomatosis
#15
LETTER
Tetsuhiko Matsuura, Takafumi Kadono, Hirotaka Koizumi, Tamihiro Kawakami, Yoshinao Soma
No abstract text is available yet for this article.
March 11, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28295544/translocation-of-the-maml2-gene-in-hidradenocarcinoma
#16
LETTER
Kosuke Yoshimi, Hiroyuki Goto, Masaki Otsuka, Shusuke Yoshikawa, Toshikazu Omodaka, Yoshio Kiyohara
No abstract text is available yet for this article.
March 11, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28295542/unexpected-recalcitrant-course-of-drug-induced-erythema-multiforme-like-eruption-and-interstitial-pneumonia-sequentially-occurring-after-nivolumab-therapy
#17
Hisashi Nomura, Hayato Takahashi, Satsuki Suzuki, Yuichi Kurihara, Shotaro Chubachi, Ichiro Kawada, Hiroyuki Yasuda, Tomoko Betsuyaku, Masayuki Amagai, Takeru Funakoshi
Vemurafenib improves survival of melanoma patients. However, cutaneous side-effects commonly occur in them. Nivolumab and ipilimumab are monoclonal antibodies against programmed death 1 and cytotoxic T-lymphocyte-associated antigen 4, both of which regulate excessive T-cell activation. Although these agents induce antitumor immunity against melanoma, the modified immune condition may result in an unexpected adverse reaction which has not been observed previously. Herein, we report a case who manifested severe erythema multiforme-like eruption with mucosal involvement associated with vemurafenib following nivolumab...
March 11, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28295533/multiple-subcutaneous-candida-abscesses-on-the-palm-and-finger-in-an-immunocompetent-patient
#18
LETTER
Hiromitsu Noguchi, Masataro Hiruma, Tadahiko Matsumoto, Takashi Yaguchi, Hikaru Tashima, Hironobu Ihn
No abstract text is available yet for this article.
March 11, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28295528/serum-soluble-interleukin-2-receptor-level-is-more-sensitive-than-angiotensin-converting-enzyme-or-lysozyme-for-diagnosis-of-sarcoidosis-and-may-be-a-marker-of-multiple-organ-involvement
#19
Chuyen Thi Hong Nguyen, Naotomo Kambe, Izumi Kishimoto, Ikuko Ueda-Hayakawa, Hiroyuki Okamoto
Skin lesions in sarcoidosis are often the initial symptoms that enable the dermatologist to be the first to diagnose this granulomatosis. However, diagnosis is sometimes very problematic. In 2015, the diagnostic criteria for sarcoidosis were updated in Japan, with elevated serum soluble interleukin-2 receptor (sIL-2R) replacing negative tuberculin reaction. Therefore, we assessed the clinical utility of sIL-2R compared with two other common markers, angiotensin-converting enzyme (ACE) and lysozyme, in patients who visited the dermatology clinic...
March 11, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28295521/exacerbation-of-infliximab-induced-paradoxical-psoriasis-after-ustekinumab-therapy
#20
LETTER
Hyun Yi Suh, Ji Young Ahn, Mi Youn Park, Jai Il Youn
No abstract text is available yet for this article.
March 11, 2017: Journal of Dermatology
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