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Journal of Clinical Psychiatry

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https://www.readbyqxmd.com/read/28297597/leptospirosis-and-depression-a-nationwide-cohort-analysis
#1
Chun-Hsiang Chiu, Ying-Chuan Wang, Cheng-Li Lin, Feng-You Lee, Chia-Hung Kao
OBJECTIVE: We conducted a retrospective cohort study to investigate whether leptospirosis is a risk factor for depression. METHOD: From the Taiwan National Health Insurance Research Database between 2000 and 2010, patients with leptospirosis (ICD-9 code 100) who did not have a history of depression (ICD-9-CM codes 296.2, 296.3, 300.4, and 311) before the index date were enrolled (leptospirosis cohort). For each patient with leptospirosis, 1 control without a history of leptospirosis and depression was randomly selected (nonleptospirosis cohort)...
March 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28297596/relationship-between-current-depressive-symptoms-and-telomere-length-in-a-large-multiethnic-sample
#2
Nicholas D Wignall, Martin Deschner, Harry M Evans, E Sherwood Brown
OBJECTIVE: Previous research has suggested that depressive symptoms may be associated with telomere length; however, findings have been mixed, and few studies have sought to generalize the results beyond samples of white individuals. The present study, conducted from August 2013 through August 2015, sought to examine the relationship between depressive symptoms and leukocyte telomere length in a large (N = 2,710), multiethnic sample (African American, white, Hispanic) and to determine if this relationship differed across ethnic/racial groups...
March 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28297595/decreased-resting-state-activity-in-the-precuneus-is-associated-with-depressive-episodes-in-recurrent-depression
#3
Chun-Hong Liu, Xin Ma, Zhen Yuan, Lu-Ping Song, Bing Jing, Hong-Yu Lu, Li-Rong Tang, Jin Fan, Martin Walter, Cun-Zhi Liu, Lihong Wang, Chuan-Yue Wang
OBJECTIVE: To investigate alterations in resting-state spontaneous brain activity in patients with major depressive disorder (MDD) experiencing multiple episodes. METHODS: Between May 2007 and September 2014, 24 recurrent and 22 remitted patients diagnosed with MDD with the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), and 69 healthy controls matched for age, sex, and educational level participated in this study. Among them, 1 healthy control was excluded due to excessive head motion...
March 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28297594/the-role-of-staging-in-planning-psychotherapeutic-interventions-in-depression
#4
Jenny Guidi, Elena Tomba, Fiammetta Cosci, Seung K Park, Giovanni A Fava
CONTEXT: The purpose of this critical review is to examine the role of staging in planning a psychotherapeutic intervention in depressive disorders. EVIDENCE ACQUISITION: English-language studies concerned with staging in depressive disorders were identified in MEDLINE, PsycINFO, and Web of Science and by manual search of the literature. Selection of articles was based on their methodological quality and implications for clinical practice. RESULTS: Staging may allow clinicians to apply a psychotherapeutic intervention to specific phases of the development of depressive disorders: certain psychotherapeutic approaches, such as well-being therapy and mindfulness-based cognitive therapy, appear to be uniquely suited for addressing the residual phase of depression, whereas interpersonal psychotherapy has been mainly tested in the acute phase...
March 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28297593/clinical-effectiveness-and-cognitive-impact-of-electroconvulsive-therapy-for-schizophrenia-a-large-retrospective-study
#5
Tyler S Kaster, Zafiris J Daskalakis, Daniel M Blumberger
OBJECTIVE: To determine the clinical effectiveness and cognitive impact of electroconvulsive therapy (ECT) in a large clinical sample of patients with schizophrenia and explore factors associated with treatment response and transient cognitive impairment. METHODS: We examined the clinical records of 144 patients with a DSM-IV diagnosis of schizophrenia or schizoaffective disorder who were treated at an academic mental health hospital from October 2009 to August 2014...
March 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28297592/a-systematized-review-of-atypical-antipsychotics-in-pregnant-women-balancing-between-risks-of-untreated-illness-and-risks-of-drug-related-adverse-effects
#6
Sarah Tosato, Umberto Albert, Simona Tomassi, Felice Iasevoli, Claudia Carmassi, Silvia Ferrari, Maria Giulia Nanni, Alessandra Nivoli, Umberto Volpe, Anna Rita Atti, Andrea Fiorillo
OBJECTIVE: To summarize risks related to (1) illness and (2) second-generation antipsychotic (SGA) treatment in pregnant women and their offspring. Concerning illness-related risks, we focused on bipolar disorder and schizophrenia, psychiatric disorders for which SGAs are preferentially prescribed. DATA SOURCES: PubMed, Ovid, Scopus, PsycINFO, and Cochrane Library were searched from the date of the first available article to October 2015 using the following key terms: pregnancy OR gestation OR bipolar disorder OR schizophrenia...
March 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28297591/estrogen-replacement-improves-verbal-memory-and-executive-control-in-oligomenorrheic-amenorrheic-athletes-in-a-randomized-controlled-trial
#7
Charumathi Baskaran, Brooke Cunningham, Franziska Plessow, Vibha Singhal, Ryan Woolley, Kathryn E Ackerman, Meghan Slattery, Hang Lee, Elizabeth A Lawson, Kamryn Eddy, Madhusmita Misra
OBJECTIVE: Both estrogen and exercise may have cognition enhancing benefits; however, young oligomenorrheic/amenorrheic athletes (OA) with estrogen deficiency have not been evaluated for cognitive deficits. Our objective was to determine whether 6 months of estrogen replacement will impact cognitive domains in OA. We hypothesized that estrogen replacement would improve verbal memory and executive control in OA. METHODS: We performed cognitive assessments at baseline and after 6 months in 48 OA (14-25 years) randomized to estrogen (EST+) (oral 30 µg ethinyl estradiol [n = 16] or transdermal 100 µg 17-β-estradiol patch [n = 13]) or no estrogen (EST-) (n = 19) in an ongoing clinical trial...
March 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28297590/insight-into-illness-and-cognition-in-schizophrenia-in-earlier-and-later-life
#8
Philip Gerretsen, Aristotle N Voineskos, Ariel Graff-Guerrero, Mahesh Menon, Bruce G Pollock, David C Mamo, Benoit H Mulsant, Tarek K Rajji
OBJECTIVE: Impaired insight into illness in schizophrenia is associated with illness severity and deficits in premorbid intellectual function, executive function, and memory. A previous study of patients aged 60 years and older found that illness severity and premorbid intellectual function accounted for variance in insight impairment. As such, we aimed to test whether similar relationships would be observed in earlier life. METHODS: A retrospective analysis was performed on 1 large sample of participants (n = 171) with a DSM-IV-TR diagnosis of schizophrenia aged 19 to 79 years acquired from 2 studies: (1) a psychosocial intervention trial for older persons with schizophrenia (June 2008 to May 2014) and (2) a diffusion tensor imaging and genetics study of psychosis across the life span (February 2007 to December 2013)...
March 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28297589/prospective-longitudinal-study-of-predictors-of-postpartum-onset-depression-in-women-with-a-history-of-major-depressive-disorder
#9
Rita Suri, Zachary N Stowe, Lee S Cohen, D Jeffrey Newport, Vivien K Burt, Ana R Aquino-Elias, Bettina T Knight, Jim Mintz, Lori L Altshuler
OBJECTIVE: Risk factors for postpartum depression in euthymic pregnant women with histories of major depressive disorder (MDD) were evaluated. METHODS: From April 2003 to March 2009, 343 pregnant women with a history of Structured Clinical Interview for DSM-IV (SCID)-diagnosed major depressive disorder were prospectively assessed from the third trimester into the postpartum period using the SCID mood module and 17-item Hamilton Depression Rating Scale (HDRS). Data from 300 subjects who completed at least 2 mood module assessments (1 within 60 days before and the other within 60 days after delivery) were analyzed for predictive associations between variables assessed in the third trimester and the development of a postpartum depression...
March 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28252882/effectiveness-of-supplementary-cognitive-behavioral-therapy-for-pharmacotherapy-resistant-depression-a-randomized-controlled-trial
#10
Atsuo Nakagawa, Dai Mitsuda, Mitsuhiro Sado, Takayuki Abe, Daisuke Fujisawa, Toshiaki Kikuchi, Satoru Iwashita, Masaru Mimura, Yutaka Ono
OBJECTIVE: Antidepressant medication is efficacious in the treatment of depression, but not all patients improve with antidepressant medication alone. Despite this treatment gap, limited evidence regarding the effectiveness of supplementing psychotherapy for pharmacotherapy-resistant depression is available. Therefore, we investigated the effectiveness of supplementing usual medication management (treatment as usual [TAU]) with cognitive-behavioral therapy (CBT) in patients with pharmacotherapy-resistant depression seeking psychiatric specialty care...
February 28, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28252881/a-randomized-controlled-pilot-study-on-mindfulness-based-cognitive-therapy-for-unipolar-depression-in-patients-with-chronic-pain
#11
Marasha de Jong, Frenk Peeters, Tim Gard, Heidi Ashih, Jim Doorley, Rosemary Walker, Laurie Rhoades, Ronald J Kulich, Karsten D Kueppenbender, Jonathan E Alpert, Elizabeth A Hoge, Willoughby B Britton, Sara W Lazar, Maurizio Fava, David Mischoulon
OBJECTIVE: Chronic pain is a disabling illness, often comorbid with depression. We performed a randomized controlled pilot study on mindfulness-based cognitive therapy (MBCT) targeting depression in a chronic pain population. METHOD: Participants with chronic pain lasting ≥ 3 months; DSM-IV major depressive disorder (MDD), dysthymic disorder, or depressive disorder not otherwise specified; and a 16-item Quick Inventory of Depressive Symptomatology-Clinician Rated (QIDS-C₁₆) score ≥ 6 were randomly assigned to MBCT (n = 26) or waitlist (n = 14)...
February 28, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28252880/intermittent-explosive-disorder-and-substance-use-disorder-analysis-of-the-national-comorbidity-survey-replication-sample
#12
Emil F Coccaro, Jennifer R Fanning, Royce Lee
OBJECTIVE: A relationship between aggression and substance use has been debated for many years. While substance use increases the risk of aggressive behavior, no studies have reported on the relationship between impulsive aggression and substance use/disorder, specifically. METHODS: We analyzed data from the community-based National Comorbidity Survey Replication (N = 9,282 subjects) in order to examine the relationship between current DSM-5 intermittent explosive disorder (IED), a disorder of impulsive aggression, and current substance use disorders (SUDs), overall, and with regard to alcohol, tobacco, and cannabis use disorders and nondisordered use...
February 28, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28199787/prolactin-elevating-antipsychotics-and-the-risk-of-endometrial-cancer
#13
Adi J Klil-Drori, Hui Yin, Haim A Abenhaim, Guillaume Galbaud du Fort, Laurent Azoulay
BACKGROUND: The use of antipsychotics may increase the risk of endometrial cancer through elevation of prolactin levels. We investigated the association between antipsychotics that are known to cause prolactin elevation and the risk of endometrial cancer. METHODS: In data from the United Kingdom Clinical Practice Research Datalink, all women who were newly treated with antipsychotics from 1990-2013 were identified and followed until 2014. Within this cohort of antipsychotic users, a nested case-control analysis was conducted...
February 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28199074/inflammatory-markers-and-brain-derived-neurotrophic-factor-as-potential-bridges-linking-bipolar-disorder-and-cardiovascular-risk-among-adolescents
#14
Jessica K Hatch, Gustavo Scola, Omodele Olowoyeye, Jordan E Collins, Ana C Andreazza, Alan Moody, Anthony J Levitt, Bradley H Strauss, Krista L Lanctot, Benjamin I Goldstein
OBJECTIVE: Bipolar disorder (BD) is associated with increased rates of cardiovascular disease (CVD). Brain-derived neurotrophic factor (BDNF) and inflammatory markers are leading biomarkers in BD. We examined whether these biomarkers underlie the link between BD and CVD proxies among adolescents with bipolar spectrum disorders. METHODS: Subjects were 60 adolescents, 13-19 years old (40 with BD and 20 healthy controls [HCs]). Semistructured interviews determined diagnoses based on DSM-IV...
February 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28199073/cognitive-control-deficits-differentiate-adolescent-suicide-ideators-from-attempters
#15
Jeremy G Stewart, Catherine R Glenn, Erika C Esposito, Christine B Cha, Matthew K Nock, Randy P Auerbach
OBJECTIVE: Mental illness and suicidal ideation are among the strongest correlates of suicidal behaviors, but few adolescents with these risk factors make a suicide attempt. Therefore, it is critical to identify factors associated with the transition from suicide ideation to attempts. The present study tested whether deficits in cognitive control in the context of suicide-relevant stimuli (ie, suicide interference) reliably differentiated adolescent ideators and attempters. METHODS: Adolescents (n = 99; 71 girls) aged 13-18 years (mean = 15...
February 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28199072/genetic-risk-score-analysis-in-early-onset-bipolar-disorder
#16
Paul E Croarkin, Joan L Luby, Kelly Cercy, Jennifer R Geske, Marin Veldic, Matthew Simonson, Paramjit T Joshi, Karen Dineen Wagner, John T Walkup, Malik M Nassan, Alfredo B Cuellar-Barboza, Leah Casuto, Susan L McElroy, Peter S Jensen, Mark A Frye, Joanna M Biernacka
OBJECTIVE: In this study, we performed a candidate genetic risk score (GRS) analysis of early-onset bipolar disorder (BD). METHODS: Treatment of Early Age Mania (TEAM) study enrollment and sample collection took place from 2003 to 2008. Mayo Clinic Bipolar Biobank samples were collected from 2009 to 2013. Genotyping and analyses for the present study took place from 2013 to 2014. The diagnosis of BD was based on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision criteria...
February 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28199071/effect-of-antipsychotic-type-and-dose-changes-on-tardive-dyskinesia-and-parkinsonism-severity-in-patients-with-a-serious-mental-illness-the-cura%C3%A3-ao-extrapyramidal-syndromes-study-xii
#17
Charlotte L Mentzel, P Roberto Bakker, Jim van Os, Marjan Drukker, Glenn E Matroos, Hans W Hoek, Marina A J Tijssen, Peter N van Harten
OBJECTIVE: To test the efficacy of current treatment recommendations for parkinsonism and tardive dyskinesia (TD) severity in patients with severe mental illness (SMI). METHODS: We present an 18-year prospective study including all 223 patients with SMI (as defined by the 1987 US National Institute of Mental Health, which were based on DSM-III-R diagnostic criteria) receiving care from the only psychiatric hospital of the former Netherlands Antilles. Eight clinical assessments (1992-2009) focused on movement disorders and medication use...
February 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28199070/randomized-controlled-trial-comparing-exercise-to-health-education-for-stimulant-use-disorder-results-from-the-ctn-0037-stimulant-reduction-intervention-using-dosed-exercise-stride-study
#18
Madhukar H Trivedi, Tracy L Greer, Chad D Rethorst, Thomas Carmody, Bruce D Grannemann, Robrina Walker, Diane Warden, Kathy Shores-Wilson, Mark Stoutenberg, Neal Oden, Meredith Silverstein, Candace Hodgkins, Lee Love, Cindy Seamans, Angela Stotts, Trey Causey, Regina P Szucs-Reed, Paul Rinaldi, Hugh Myrick, Michele Straus, David Liu, Robert Lindblad, Timothy Church, Steven N Blair, Edward V Nunes
OBJECTIVE: To evaluate exercise as a treatment for stimulant use disorders. METHODS: The STimulant Reduction Intervention using Dosed Exercise (STRIDE) study was a randomized clinical trial conducted in 9 residential addiction treatment programs across the United States from July 2010 to February 2013. Of 497 adults referred to the study, 302 met all eligibility criteria, including DSM-IV criteria for stimulant abuse and/or dependence, and were randomized to either a dosed exercise intervention (Exercise) or a health education intervention (Health Education) control, both augmenting treatment as usual and conducted thrice weekly for 12 weeks...
February 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28199069/adding-clinical-validity-to-the-statistical-power-of-large-scale-epidemiological-surveys-on-internet-addiction-in-adolescence-a-combined-approach-to-investigate-psychopathology-and-development-specific-personality-traits-associated-with-internet-addiction
#19
Kai W Müller, Michael Dreier, Eva Duven, Sebastian Giralt, Manfred E Beutel, Klaus Wölfling
OBJECTIVE: Research has indicated that internet addiction is associated with psychosocial maladjustment in adolescence. Many epidemiologic surveys are lacking representativeness, and knowledge on disorder-specific risk factors is scarce. One weakness of epidemiologic studies often regards their lack of generalizability to clinical reality. The aim of this study was to provide a detailed description of internet addiction among adolescents, focusing on its prevalence in a population-based context, psychopathological correlates, and predisposing factors...
February 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28199068/the-relationship-between-stressful-life-events-and-axis-i-diagnoses-among-adolescent-offspring-of-probands-with-bipolar-and-non-bipolar-psychiatric-disorders-and-healthy-controls-the-pittsburgh-bipolar-offspring-study-bios
#20
Lisa A Pan, Tina R Goldstein, Brian T Rooks, Mary Hickey, Jie Yu Fan, John Merranko, Kelly Monk, Rasim S Diler, Dara J Sakolsky, Daniella Hafeman, Satish Iyengar, Benjamin Goldstein, David J Kupfer, David A Axelson, David A Brent, Boris Birmaher
BACKGROUND: Previous studies have explored the role of stressful life events in the development of mood disorders. We examined the frequency and nature of stressful life events as measured by the Stressful Life Events Schedule (SLES) among 3 groups of adolescent offspring of probands with bipolar (BD), with non-BD psychiatric disorders, and healthy controls. Furthermore, we examined the relationship between stressful life events and the presence of DSM-IV Axis I disorders in these offspring...
February 14, 2017: Journal of Clinical Psychiatry
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