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Journal of Child and Adolescent Psychopharmacology

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https://www.readbyqxmd.com/read/29336603/comparison-of-unlicensed-and-off-label-use-of-antipsychotics-prescribed-to-child-and-adolescent-psychiatric-outpatients-for-treatment-of-mental-and-behavioral-disorders-with-different-guidelines-the-china-food-and-drug-administration-versus-the-fda
#1
Xiuqing Zhu, Jinqing Hu, Bin Sun, Shuhua Deng, Yuguan Wen, Weijia Chen, Chang Qiu, Dewei Shang, Ming Zhang
OBJECTIVES: This study aims to compare the prevalence of unlicensed and off-label use of antipsychotics among child and adolescent psychiatric outpatients with guidelines proposed by the China Food and Drug Administration (CFDA) and the U.S. Food and Drug Administration (FDA), and to identify factors associated with inconsistencies between the two regulations. METHODS: A retrospective analysis of 29,326 drug prescriptions for child and adolescent outpatients from the Affiliated Brain Hospital of Guangzhou Medical University was conducted...
January 16, 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29315010/escitalopram-in-the-treatment-of-a-3-year-old-child-with-posttraumatic-feeding-disorder
#2
Esra Hoşoğlu, Ömer Faruk Akça
No abstract text is available yet for this article.
January 9, 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29297696/second-generation-antipsychotics-in-adolescent-psychiatric-patients-metabolic-effects-and-impact-of-an-early-weight-change-to-predict-longer-term-weight-gain
#3
Frederik Vandenberghe, Alexandra Najar-Giroud, Laurent Holzer, Philippe Conus, Chin B Eap, Anne-Emmanuelle Ambresin
OBJECTIVES: To examine the metabolic profile of adolescents at baseline and to determine the potential predictive power of a 1-month weight gain (WG) on weight changes during longer term second-generation antipsychotic (SGA) treatment. METHODS: A retrospective chart review study, including patients between 13 and 18 years of age and treated with SGA, was conducted. Available data at baseline, 1, 3, and 12 months of treatment were recorded. RESULTS: Four hundred fifty-six patients were included, with a median age of 15 years...
January 3, 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29266976/characteristics-associated-with-drug-prescription-and-compliance-among-young-children-with-autism-spectrum-disorder
#4
Gal Meiri, Hen Azoulay, Idan Menashe
OBJECTIVES: Psychotropic drugs are prescribed to people with autism spectrum disorder (ASD) usually as a means to alleviate comorbidities associated with the disorder. However, despite the uncertainty regarding the efficacy of these treatments for ASD, their prevalence is continuously increasing. The goal of this study was to understand the characteristics associated with drug prescription and compliance among young children with ASD. MATERIALS AND METHODS: We studied patterns of drug utilization in a population-based sample of 211 young children with ASD in Southern Israel...
December 21, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29266970/comparison-of-depression-and-burnout-levels-of-mothers-of-children-with-attention-deficit-hyperactivity-disorder-before-and-after-treatment
#5
Cem Gokcen, Seyma Coskun, Meryem Ozlem Kutuk
OBJECTIVE: This study aimed to compare the depression and burnout levels of mothers of children having attention-deficit/hyperactivity disorder (ADHD) between the child's pre- and posttreatment periods. METHOD: The study sample consisted of 40 children aged between 4 and 10 years and their mothers. Initially, 40 cases participated, but during the follow-up, 19 cases dropped out. The Beck Depression Inventory (BDI), the Maslach Burnout Inventory (MBI), and the Turgay DSM-IV Based Child and Adolescent Behaviour Disorders Screening and Rating Scale (T-DSM-IV-S) were used...
December 21, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29240460/two-adolescent-cases-of-psychotropic-related-nonaffective-oniomania
#6
Ahmed Naguy, Waleed Abdelhakim, Ali Al-Tajali
Oniomania, or compulsive buying disorder (CBD), an acquisitive impulse dyscontrol disorder, is not officially acknowledged in current classificatory systems, but remains a valid diagnostic construct on clinical grounds. In this study, authors report on two interesting adolescent cases of "secondary" oniomania related to use of psychotropics. This is followed by discussion of putative pharmacodynamic mechanisms, working differential, and an overview of current literature on CBD.
December 14, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29211967/efficacy-and-safety-of-amphetamine-extended-release-oral-suspension-in-children-with-attention-deficit-hyperactivity-disorder
#7
Ann C Childress, Sharon B Wigal, Matthew N Brams, John M Turnbow, Yulia Pincus, Heidi W Belden, Sally A Berry
OBJECTIVES: To determine the efficacy and safety of amphetamine extended-release oral suspension (AMPH EROS) in the treatment of attention-deficit/hyperactivity disorder (ADHD) in a dose-optimized, randomized, double-blind, parallel-group study. METHODS: Boys and girls aged 6 to 12 years diagnosed with ADHD were enrolled. During a 5-week, open-label, dose-optimization phase, patients began treatment with 2.5 or 5 mg/day of AMPH EROS; doses were titrated until an optimal dose (maximum 20 mg/day) was reached...
December 6, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29189044/desvenlafaxine-versus-placebo-in-a-fluoxetine-referenced-study-of-children-and-adolescents-with-major-depressive-disorder
#8
Karen L Weihs, William Murphy, Richat Abbas, Deborah Chiles, Richard D England, Sara Ramaker, Dalia B Wajsbrot
OBJECTIVES: To evaluate the short-term efficacy and safety of desvenlafaxine (25-50 mg/d) compared with placebo in children and adolescents with major depressive disorder (MDD). METHODS: Outpatient children (7-11 years) and adolescents (12-17 years) who met DSM-IV-TR criteria for MDD and had screening and baseline Children's Depression Rating Scale-Revised (CDRS-R) total scores >40 were randomly assigned to 8-week treatment with placebo, desvenlafaxine (25, 35, or 50 mg/d based on baseline weight), or fluoxetine (20 mg/d)...
November 30, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29185786/desvenlafaxine-versus-placebo-in-the-treatment-of-children-and-adolescents-with-major-depressive-disorder
#9
Sarah Atkinson, Shannon Lubaczewski, Sara Ramaker, Richard D England, Dalia B Wajsbrot, Richat Abbas, Robert L Findling
OBJECTIVE: To evaluate the short-term efficacy and safety of desvenlafaxine versus placebo in the treatment of children and adolescents with major depressive disorder (MDD). METHODS: Outpatient children (7-11 years) and adolescents (12-17 years) who met DSM-IV-TR criteria for MDD and had screening and baseline Children's Depression Rating Scale-Revised (CDRS-R) total scores >40 were randomly assigned to 8 weeks of treatment with placebo, low exposure desvenlafaxine (20, 30, or 35 mg/day based on baseline weight), or higher exposure desvenlafaxine (25, 35, or 50 mg/day based on baseline weight)...
November 29, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29172673/how-informative-are-self-reported-adult-attention-deficit-hyperactivity-disorder-symptoms-an-examination-of-the-agreement-between-the-adult-attention-deficit-hyperactivity-disorder-self-report-scale-v1-1-and-adult-attention-deficit-hyperactivity-disorder-investigator
#10
Michael J Silverstein, Stephen V Faraone, Samuel Alperin, Joseph Biederman, Thomas J Spencer, Lenard A Adler
OBJECTIVES: Assess agreement between self-ratings via the adult attention-deficit/hyperactivity disorder (ADHD) Self-Report Scale (ASRS)-v1.1 Symptom Checklist and clinician ratings via the adult ADHD Investigator Symptom Rating Scale (AISRS) expanded version using DSM-5 adult ADHD patients (referred sample) and ADHD controls (recruited from a primary care physician practice). METHODS: The ASRS v1.1 Symptom Checklist was administered to measure self-reported ADHD symptoms and impairment, the Adult ADHD Clinical Diagnostic Scale v1...
November 27, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29161523/does-acute-propranolol-treatment-prevent-posttraumatic-stress-disorder-anxiety-and-depression-in-children-with-burns
#11
Laura Rosenberg, Marta Rosenberg, Sherri Sharp, Christopher R Thomas, Helen F Humphries, Charles E Holzer, David N Herndon, Walter J Meyer
OBJECTIVE: This study examined whether acute propranolol treatment prevented posttraumatic stress disorder (PTSD), anxiety, and depression in children hospitalized in the pediatric intensive care unit for large burns. We hypothesized that the prevalence of PTSD, anxiety, and depression would be significantly less in the propranolol than nonpropranolol groups. METHODS: Children who had previously participated in a randomized controlled clinical trial of acute propranolol and nonpropranolol controls were invited to participate in long-term follow-up interviews...
November 21, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29131677/methylphenidate-has-superior-efficacy-over-parent-child-interaction-therapy-for-preschool-children-with-disruptive-behaviors
#12
Lianne van der Veen-Mulders, Barbara J van den Hoofdakker, Maaike H Nauta, Paul Emmelkamp, Pieter J Hoekstra
OBJECTIVE: To compare the effectiveness between parent-child interaction therapy (PCIT) and methylphenidate in preschool children with attention-deficit/hyperactivity disorder (ADHD) symptoms and disruptive behaviors who had remaining significant behavior problems after previous behavioral parent training. METHODS: We included 35 preschool children, ranging in age between 3.4 and 6.0 years. Participants were randomized to PCIT (n = 18) or methylphenidate (n = 17)...
November 13, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29131668/nasal-bleeding-probably-associated-with-methylphenidate
#13
Sibelnur Avcil
No abstract text is available yet for this article.
November 13, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29131655/psychotropic-drug-prescription-in-adolescents-a-retrospective-study-in-a-swiss-psychiatric-university-hospital
#14
Nicolas Ansermot, Véronique Jordanov, Michal Smogur, Laurent Holzer, Chin B Eap
OBJECTIVES: This retrospective study aims to evaluate off-label prescriptions and administrations of psychotropic medications in adolescents in a university psychiatric hospital in Switzerland. METHODS: Data were collected during the entire stays from the electronic database for 76 inpatients in 2008 and 76 inpatients in 2014. Data collected included gender, age, psychiatric diagnosis, duration of hospitalization, and psychotropic drug prescriptions and administrations...
November 13, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29112476/cross-sectional-evaluation-of-plasma-vitamin-d-levels-in-a-large-cohort-of-italian-patients-with-pediatric-autoimmune-neuropsychiatric-disorders-associated-with-streptococcal-infections
#15
Stefano Stagi, Gemma Lepri, Donato Rigante, Marco Matucci Cerinic, Fernanda Falcini
BACKGROUND: Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) are immune-mediated diseases characterized by obsessive-compulsive symptoms and/or tics triggered by group A Streptococcus infections. Despite the well-known action of 25-hydroxyvitamin D [25(OH)D] on different conditions driven by systemic inflammation, there are no data about the 25(OH)D status in patients with PANDAS. AIMS: To evaluate plasma 25(OH)D levels in a large cohort of children and adolescents with PANDAS and comparing the results with healthy controls...
November 7, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29112461/calcium-and-vitamin-d-supplementation-in-boys-with-risperidone-induced-hyperprolactinemia-a-randomized-placebo-controlled-pilot-study
#16
Chadi A Calarge, James A Mills, Ekhard E Ziegler, Janet A Schlechte
BACKGROUND: The chronic use of antipsychotics has been associated with impaired bone mineralization, partially mediated by hyperprolactinemia. We examined if calcium and vitamin D supplementation promote bone mineral accrual in boys with risperidone-induced hyperprolactinemia. METHODS: Between February 2009 and November 2013, medically healthy, 5- to 17-year-old boys were enrolled in a 36-week double-blind, placebo-controlled study, examining the skeletal effects of supplementation with 1250 mg calcium carbonate and 400 IU of vitamin D3 in risperidone-induced hyperprolactinemia...
November 7, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29112459/atomoxetine-parent-training-and-their-effects-on-sleep-in-youth-with-autism-spectrum-disorder-and-attention-deficit-hyperactivity-disorder
#17
Jill A Hollway, Marrisa Mendoza-Burcham, Rebecca Andridge, Michael G Aman, Benjamin Handen, L Eugene Arnold, Luc Lecavalier, Craig Williams, Laura Silverman, Tristram Smith
OBJECTIVE: Sleep disturbance is often a problem for children with either autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD). Psychostimulant medications used to treat ADHD symptoms can exacerbate this problem. For children with ASD and ADHD, atomoxetine (ATX) is a viable alternative to psychostimulants. We investigated the effects of ATX and a manualized parent training (PT) program targeting noncompliance, on the sleep quality of children with ASD and ADHD...
November 7, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29099621/atomoxetine-related-trichotillomania-in-a-boy-with-attention-deficit-hyperactivity-disorder
#18
İsmail Akaltun, Tayfun Kara
No abstract text is available yet for this article.
November 3, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29091743/movement-disorders-in-children-and-adolescents-receiving-antipsychotic-pharmacotherapy-a-population-based-study
#19
Robert G Biscontri, Sarita Jha, David M Collins, Shawn Bugden, Laurence Y Katz, Silvia Alessi-Severini
OBJECTIVES: To describe a cohort of young users of risperidone and quetiapine in the province of Manitoba (Canada) and assess the risk for movement disorders in the two treatments. METHODS: This was a population-based study conducted on all residents of the province of 19 years of age and younger who received prescriptions for risperidone or quetiapine between April 1, 1996, and March 31, 2011. Incident rates of antipsychotic use were reported. The risk for movement disorders in patients treated with quetiapine compared with those treated with risperidone was assessed by time-to-event analysis using Cox proportional hazards models...
November 1, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29227729/from-the-editor-in-chief-s-desk
#20
Harold S Koplewicz
No abstract text is available yet for this article.
December 2017: Journal of Child and Adolescent Psychopharmacology
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