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Journal of Child and Adolescent Psychopharmacology

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https://www.readbyqxmd.com/read/27901342/correction-to-journal-of-child-and-adolescent-psychopharmacology-2015-25-738-748
#1
(no author information available yet)
No abstract text is available yet for this article.
November 30, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27893955/using-a-patient-centered-outcome-measure-to-test-methylphenidate-versus-placebo-in-children-with-autism-spectrum-disorder
#2
Lawrence Scahill, Karen Bearss, Rena Sarhangian, Christopher J McDougle, L Eugene Arnold, Michael G Aman, James T McCracken, Elaine Tierney, Scott Gillespie, Valentina Postorino, Benedetto Vitiello
OBJECTIVES: Parent rating scales are commonly used to evaluate change in clinical trials. Despite advantages, these measures may not capture parental impression of the child's most salient problems. We examine the use of parent target problems (PTPs) in a randomized trial of methylphenidate (MPH) in children with autism spectrum disorder and symptoms of attention-deficit/hyperactivity disorder. METHODS: This multisite, 4-week, randomized crossover trial compared three dose levels (low, medium, and high) of MPH with placebo...
November 28, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27893294/management-of-multifactorial-infant-delirium-with-intravenous-haloperidol-in-the-setting-of-over-sedation-and-poor-enteral-absorption
#3
Erin F Carlton, Madeline K Mahowald, Nasuh Malas
No abstract text is available yet for this article.
November 28, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27893286/cessation-of-nocturnal-enuresis-with-aripiprazole
#4
Saliha Kılınç, Arzu Hergüner, Sabri Hergüner
No abstract text is available yet for this article.
November 28, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27845858/atomoxetine-related-change-in-sluggish-cognitive-tempo-is-partially-independent-of-change-in-attention-deficit-hyperactivity-disorder-inattentive-symptoms
#5
Keith McBurnett, David Clemow, David Williams, Miguel Villodas, Linda Wietecha, Russell Barkley
OBJECTIVES: To evaluate effects of atomoxetine versus placebo on sluggish cognitive tempo (SCT) and determine factors affecting improvement of SCT in children with attention-deficit/hyperactivity disorder (ADHD) with dyslexia (ADHD+D) or dyslexia only. METHODS: This is a post hoc analysis of a 16-week placebo-controlled, double-blind randomized phase of a previously reported atomoxetine study in children aged 10-16 years with ADHD+D, Dyslexia-only, or ADHD-only (no placebo arm)...
November 15, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27830935/use-of-computer-vision-tools-to-identify-behavioral-markers-of-pediatric-obsessive-compulsive-disorder-a-pilot-study
#6
Gail A Bernstein, Tasoulla Hadjiyanni, Kathryn R Cullen, Julia W Robinson, Elizabeth C Harris, Austin D Young, Joshua Fasching, Nicholas Walczak, Susanne Lee, Vassilios Morellas, Nikolaos Papanikolopoulos
OBJECTIVES: The clinical presentation of pediatric obsessive-compulsive disorder (OCD) is heterogeneous, which is a stumbling block to understanding pathophysiology and to developing new treatments. A major shift in psychiatry, embodied in the Research Domain Criteria (RDoC) initiative of National Institute of Mental Health, recognizes the pitfalls of categorizing mental illnesses using diagnostic criteria. Instead, RDoC encourages researchers to use a dimensional approach, focusing on narrower domains of psychopathology to characterize brain-behavior relationships...
November 10, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27813651/a-systematic-review-of-the-use-of-bupropion-for-attention-deficit-hyperactivity-disorder-in-children-and-adolescents
#7
Qin Xiang Ng
INTRODUCTION: Attention-deficit/hyperactivity disorder (ADHD) is one of the most prevalent neuropsychiatric disorders of childhood and adolescence. Stimulants are usually the first choice of drug; however, as many as 20% of patients do not respond to them. Stimulants may also worsen comorbid sleep, mood, and anxiety disorders, and they are associated with problems of misuse and diversion. Bupropion, a dopamine and norepinephrine reuptake inhibitor, is a promising nonstimulant alternative with reports of positive outcomes for ADHD management in both adolescent and adult populations...
November 4, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27797585/beneficial-effects-of-everolimus-on-autism-and-attention-deficit-hyperactivity-disorder-symptoms-in-a-group-of-patients-with-tuberous-sclerosis-complex
#8
Ayse Kilincaslan, Burcu Ece Kok, Pinar Tekturk, Cengiz Yalcinkaya, Cigdem Ozkara, Zuhal Yapici
OBJECTIVES: Such neuropsychiatric symptoms as autism spectrum disorders, attention-deficit/hyperactivity disorder (ADHD), intellectual disability, aggression, and epilepsy are very common in patients with tuberous sclerosis complex (TSC). Everolimus, a mammalian target of rapamycin (mTOR) inhibitor, is a recent and effective treatment for TSC patients with giant cell astrocytomas and renal angiomyolipoma, and it has been shown to have a potential to reduce tumor volume. However, there is a paucity of studies on the effects of everolimus on neuropsychiatric symptoms...
October 31, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27782771/beta-blockers-for-exams-identify-students-at-high-risk-of-psychiatric-morbidity
#9
Jawad H Butt, Søren Dalsgaard, Christian Torp-Pedersen, Lars Køber, Gunnar H Gislason, Christina Kruuse, Emil L Fosbøl
OBJECTIVES: Beta-blockers relieve the autonomic symptoms of exam-related anxiety and may be beneficial in exam-related and performance anxiety, but knowledge on related psychiatric outcomes is unknown. We hypothesized that beta-blocker therapy for exam-related anxiety identifies young students at risk of later psychiatric events. METHODS: Using Danish nationwide administrative registries, we studied healthy students aged 14-30 years (1996-2012) with a first-time claimed prescription for a beta-blocker during the exam period (May-June); students who were prescribed a beta-blocker for medical reasons were excluded...
October 26, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27779425/serum-concentration-of-risperidone-and-adverse-effects-in-children-and-adolescents
#10
Amilton Dos Santos-Júnior, Mariana Leite Tamascia, Raquel Lorenzetti, Osmar Henrique Della Torre, Lúcia Arisaka Paes, Thiago Salum Fontana, Adriana Perez Ferreira-Neto, Taciane Barbosa Henriques, Stephen Hyslop, Maricilda Palandi de Mello, Eloisa Helena Rubello Valler Celeri, Paulo Dalgalarrondo, Gil Guerra-Júnior
No abstract text is available yet for this article.
October 25, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27768380/inhibited-temperament-and-hippocampal-volume-in-offspring-of-parents-with-bipolar-disorder
#11
Eunjoo Kim, Amy Garrett, Spencer Boucher, Min-Hyeon Park, Meghan Howe, Erica Sanders, Ryan G Kelley, Allan L Reiss, Kiki D Chang, Manpreet K Singh
BACKGROUND: Prior studies have suggested that inhibited temperament may be associated with an increased risk for developing anxiety or mood disorder, including bipolar disorder. However, the neurobiological basis for this increased risk is unknown. The aim of this study was to examine temperament in symptomatic and asymptomatic child offspring of parents with bipolar disorder (OBD) and to investigate whether inhibited temperament is associated with aberrant hippocampal volumes compared with healthy control (HC) youth...
October 21, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27754700/effect-of-aptensio-xr-methylphenidate-hcl-extended-release-capsules-on-sleep-in-children-with-attention-deficit-hyperactivity-disorder
#12
Judith Owens, Margaret Weiss, Earl Nordbrock, Greg Mattingly, Sharon Wigal, Laurence L Greenhill, Wei-Wei Chang, Ann Childress, Robert J Kupper, Akwete Adjei
OBJECTIVE: To evaluate measures of sleep (exploratory endpoints) in two pivotal studies of a multilayer bead extended-release methylphenidate (MPH-MLR) treatment of attention-deficit/hyperactivity disorder in children. METHODS: Study 1 evaluated the time course of response to MPH-MLR (n = 26) patients in an analog classroom setting through four phases: screening (≤28 days), open label (OL) dose optimization (4 weeks), double-blind (DB) crossover (2 weeks; placebo vs...
October 18, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27726426/no-apparent-cardiac-conduction-effects-of-acute-treatment-with-risperidone-in-children-with-autism-spectrum-disorder
#13
Lan Chi Vo, Christopher Snyder, Courtney McCracken, Christopher J McDougle, James T McCracken, Michael G Aman, Elaine Tierney, L Eugene Arnold, Daniel Levi, Michael Kelleman, Deirdre Carroll, John Morrissey, Benedetto Vitiello, Lawrence Scahill
OBJECTIVES: Risperidone is approved for the treatment of serious behavioral problems in children with autism spectrum disorder (ASD). This study examined the effects of risperidone on cardiac conduction in children with ASD. METHODS: Data were collected from an 8-week, five-site trial conducted by the Research Units on Pediatric Psychopharmacology Autism Network. Children (age 5-17 years) were randomly assigned to risperidone (n = 49) or placebo (n = 52) under double-blind conditions...
October 11, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27676420/a-52-week-study-of-olanzapine-with-a-randomized-behavioral-weight-counseling-intervention-in-adolescents-with-schizophrenia-or-bipolar-i-disorder
#14
Holland C Detke, Melissa P DelBello, John Landry, Vicki Poole Hoffmann, Alexandra Heinloth, Ralf W Dittmann
OBJECTIVES: To evaluate the 52-week safety/tolerability of oral olanzapine for adolescents with schizophrenia or bipolar mania and compare effectiveness of a standard versus intense behavioral weight intervention in mitigating risk of weight gain. METHODS: Patients 13-17 years old with schizophrenia (Brief Psychiatric Rating Scale for Children [BPRS-C] total score >30; item score ≥3 for hallucinations, delusions, or peculiar fantasies) or bipolar I disorder (manic or mixed episode; Young Mania Rating Scale [YMRS] total score ≥15) received open-label olanzapine (2...
September 27, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27626945/impact-of-stimulant-medication-use-on-heart-rate-and-systolic-blood-pressure-during-submaximal-exercise-treadmill-testing-in-adolescents
#15
Arthur N Westover, Paul A Nakonezny, Bryon Adinoff, Edson Sherwood Brown, Ethan A Halm
OBJECTIVES: Inappropriately decreased heart rate (HR) during peak exercise and delayed heart rate recovery (HRR) has been observed in adult users of stimulant medications who underwent exercise testing, suggesting autonomic adaptation to chronic stimulant exposure. In the general population, this pattern of hemodynamic changes is associated with increased mortality risk. Whether the same pattern of hemodynamic changes might be observed in adolescent stimulant medication users undergoing exercise testing is unknown...
September 14, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27854544/from-the-editor-in-chief-s-desk
#16
Harold S Koplewicz
No abstract text is available yet for this article.
November 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27854543/obsessive-compulsive-disorder-tics-and-autoinflammatory-diseases-beyond-pandas
#17
Blanca Garcia-Delgar, Astrid Morer, Maxwell J Luber, Barbara J Coffey
No abstract text is available yet for this article.
November 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27768385/influence-of-naltrexone-bupropion-combination-treatment-on-body-mass-index-in-prader-willi-syndrome-re-prader-willi-syndrome-management-of-impulsivity-and-hyperphagia-in-an-adolescent-by-puri-et-al
#18
Amanda Hor, Louise Purtell
No abstract text is available yet for this article.
November 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27389348/weight-gain-effects-of-second-generation-antipsychotic-treatment-in-autism-spectrum-disorder
#19
Yesie Yoon, Logan K Wink, Ernest V Pedapati, Paul S Horn, Craig A Erickson
OBJECTIVE: Irritability (aggression, self-injury, and severe tantrums) associated with autism spectrum disorder (ASD) is often treated with second-generation antipsychotics (SGAs), which are well known for their associated risk of weight gain in youth. Recent reports suggest that youth with ASD treated with SGAs may suffer more pronounced weight gain than typically developing children. In this study, we present a comprehensive comparison of weight gain effects of five SGAs in a clinical population of youth with ASD...
November 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27315155/often-asked-but-rarely-answered-can-asians-meet-dsm-5-icd-10-autism-spectrum-disorder-criteria
#20
So Hyun Kim, Young Shin Kim, Yun-Joo Koh, Eun-Chung Lim, Soo-Jeong Kim, Bennett L Leventhal
OBJECTIVES: To evaluate whether Asian (Korean children) populations can be validly diagnosed with autism spectrum disorder (ASD) using Western-based diagnostic instruments and criteria based on Diagnostic and Statistical Manual on Mental Disorders, 5th edition (DSM-5). METHODS: Participants included an epidemiologically ascertained 7-14-year-old (N = 292) South Korean cohort from a larger prevalence study (N = 55,266). Main outcomes were based on Western-based diagnostic methods for Korean children using gold standard instruments, Autism Diagnostic Interview-Revised, and Autism Diagnostic Observation Schedule...
November 2016: Journal of Child and Adolescent Psychopharmacology
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