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Journal of Asthma: Official Journal of the Association for the Care of Asthma

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https://www.readbyqxmd.com/read/29969920/adherence-barriers-to-inhaled-medicines-in-japanese-older-patients-with-asthma-evaluated-using-the-adherence-starts-with-knowledge-20-ask-20-questionnaire
#1
Jun Sasaki, Tomotaka Kawayama, Makoto Yoshida, Koichiro Takahashi, Kazuhiko Fujii, Kentaro Machida, Takashi Kinoshita, Tomoaki Hoshino
OBJECTIVE: We investigated adherence barriers to inhaled medicines among older compared to younger adults with asthma in Japan. METHODS: Adherence barriers to inhaled medicines were evaluated in 251 Japanese older (n = 138) and younger (n = 113) adults with asthma using the self-reporting "Adherence Starts with Knowledge 20" (ASK-20) questionnaire. RESULTS: There were fewer older adults with poor adherence to inhaled medicines than younger adults...
September 19, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30212239/comparison-between-montelukast-and-tiotropium-as-add-on-therapy-to-inhaled-corticosteroids-plus-a-long-acting-%C3%AE-2-agonist-in-for-patients-with-asthma
#2
Makoto Hoshino, Kenta Akitsu, Junichi Ohtawa
OBJECTIVE: Asthma often remains uncontrolled despite treatment with inhaled corticosteroids (ICS) alone or with ICS plus a long-acting β2 -agonist (LABA). The recommended alternative is the addition of either montelukast or tiotropium. The aim of this study was to compare the effects of montelukast and tiotropium on airway inflammation and remodeling in persistent asthma. METHODS: Eighty-seven patients with asthma were treated with budesonide and formoterol (640/18 μg); then, the patients were randomly allocated to three groups to receive oral montelukast (10 mg/day), inhaled tiotropium (5 μg/day), or no add-on to the maintenance therapy for 48 weeks...
September 13, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30207821/improving-efficiency-of-pediatric-emergency-asthma-treatment-by-using-metered-dose-inhaler
#3
Ruth Abaya, Eva M Delgado, Richard J Scarfone, Ann Marie Reardon, Bonnie Rodio, Denise Simpkins, Vaidehi Mehta, Katie Hayes, Joseph J Zorc
OBJECTIVE: Evidence suggests using metered dose inhaler (MDI) to treat acute asthma in the Emergency Department reduces length of stay, though methods of implementation are lacking. We modified a treatment pathway to recommend use of MDI for mild-moderate asthma in a pediatric ED. METHODS: A baseline review assessed discharged patients >2 years with an asthma diagnosis and non-emergent Emergency Severity Index triage assessment (3/4). Our multi-disciplinary team developed an intervention to increase MDI use instead of continuous albuterol (CA) using the following: (1) Redesign the asthma pathway and order set recommending MDI for ESI 3/4 patients...
September 12, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30207818/the-association-of-environmental-meteorological-and-pollen-count-variables-with-asthma-related-emergency-department-visits-and-hospitalizations-in-the-bronx
#4
Jonathan Witonsky, Ryan Abraham, Jennifer Toh, Tulsi Desai, Mili Shum, David Rosenstreich, Sunit P Jariwala
OBJECTIVE: To better understand how meteorological variables, air quality variables, and pollen counts collectively contribute to asthma-related emergency department visits (AREDV) and asthma-related hospitalizations (ARH) among pediatric and adult patients in the New York City borough of the Bronx. METHODS: The numbers of daily adult and pediatric AREDV and ARH from 2001 to 2008 were obtained from three Bronx hospitals. After removing outliers, interpolating missing data, and standardizing variable values by scaling the data using z-scores, data were analyzed using Spearman rank tests and linear regression models for the full year and each season...
September 12, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30207809/la-phonospirometry-technique-compared-to-pediatric-respiratory-assessment-measure-and-peak-expiratory-flow-measurement-as-a-novel-technique-to-assess-the-severity-of-an-asthma-exacerbation
#5
Kelly Ochoa, Jori Richman, Vincent J Wang
OBJECTIVE: Asthma is a common chronic disease treated in emergency departments. The measurements of Peak Expiratory Flow (PEF) and Pediatric Respiratory Assessment Measure (PRAM) scores have been recommended as objective techniques in the assessment of acute asthma exacerbations, but have multiple barriers limiting their use. The Los Angeles phonospirometry technique is an easier, trans-cultural technique. The technique assesses dyspnea by measuring how many seconds a child is able to chant "LA LA LA" in a single breath...
September 12, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30207802/examination-of-the-uses-needs-and-preferences-for-health-technology-use-in-adolescents-with-asthma
#6
Rachelle R Ramsey, Julia K Carmody, Christina E Holbein, Theresa W Guilbert, Kevin A Hommel
OBJECTIVE: To examine the health technology uses and preferences of adolescents with asthma using a qualitative descriptive individual interview approach. METHODS: Twenty adolescents were recruited from regularly scheduled asthma clinic appointments from February to July 2016. Patients were interviewed about their technology use and ways in which health technology could improve their asthma management using an open-ended semi-structured interview format. Interviews were audio recorded, transcribed, and coded into themes...
September 12, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972079/step-up-and-step-down-treatments-for-optimal-asthma-control-in-children-and-adolescents
#7
Jonathan A Bernstein, Lyndon Mansfield
OBJECTIVE: To review therapeutic options for stepwise management of pediatric asthma in the context of this population's unique needs such as potential effects of asthma, treatments, or both on growth and psychosocial development, and caregiver involvement. DATA SOURCES AND STUDY SELECTION: We conducted PubMed searches to identify relevant articles then reviewed resultant articles, guidelines for asthma management in children, and articles from personal files. RESULTS: Stepwise management of asthma, similar to adults, is recommended for children in current global and US guidelines...
September 12, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30063840/telemonitoring-in-asthma-control-a-randomized-controlled-trial
#8
Tiva Nemanic, Irena Sarc, Sabina Skrgat, Matjaz Flezar, Iztok Cukjati, Mateja Marc Malovrh
OBJECTIVE: Telemonitoring seems to be a useful tool for patients' management. The aim of our project was to test the applicability and potential effects of a 12-month telemonitoring of patients with asthma supported by information and communication technologies. METHODS: We included 100 patients with asthma followed in the outpatient pulmonary clinic in a randomized controlled clinical trial. The patients' data were collected by study questionnaires and lung function tests at the inclusion and at the end of interventional period...
September 5, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29985082/enhanced-pause-correlates-with-airway-neutrophils-and-airway-epithelial-injury-in-asthmatic-mice-treated-with-dexamethasone
#9
Chao Niu, Ting Wang, Wenjing Zou, Jie Hu, Linyan Ying, Mingxiang Zhang, Jingyue Liu, Daiyin Tian, Jihong Dai, Zhengxiu Luo, Enmei Liu, Lin Zou, Yi Xiong, Zhou Fu
OBJECTIVE: To investigate the correlations among airway inflammation, airway epithelial injury and airway hyperresponsiveness (AHR) in asthmatic mice treated with dexamethasone. METHODS: Female BALB/c mice were sensitized with intraperitoneal and hypodermic injections of ovalbumin (OVA) and aluminum on days 0, 7 and 14, challenged with OVA starting on day 21 for 10 days, and treated with dexamethasone via intraperitoneal injection starting on day 28 for 3 days. Female C57BL/6 mice were treated intranasally with house dust mite (HDM) on days 1 and 14, challenged intranasally with HDM on days 21, 23, 25, 27 and 29, and treated with sivelestat (a selective neutrophil elastase inhibitor) via intraperitoneal injection after each challenge...
September 5, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29984589/the-impact-of-traditional-literacy-and-education-on-health-literacy-in-adolescents-with-asthma
#10
Desha M Jordan, Jeana S Bush, Dennis R Ownby, Jennifer L Waller, Martha S Tingen
INTRODUCTION: People with low health literacy have poorer self-management of chronic diseases like asthma. Studies of parent health literacy and education level on the management of children's chronic illnesses reveal inconclusive results. We hypothesized a correlation between parent and adolescent health literacy in teens with asthma. METHODS: Sociodemographic data were obtained; health literacy was assessed on adolescents and parents with three instruments: Rapid Estimate of Adolescent/Adult Literacy in Medicine (REALM), Single Item Literacy Screener (SILS) and Newest Vital Sign (NVS)...
September 5, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30003833/a-cost-effectiveness-analysis-of-reslizumab-in-the-treatment-of-poorly-controlled-eosinophilic-asthma
#11
Jenny Lam, Joel W Hay, Jonathan Salcedo, Nicholas J Kenyon
INTRODUCTION: Poorly controlled severe eosinophilic asthma is difficult and costly to manage. Reslizumab, an add-on treatment for adults with severe eosinophilic asthma, reduces the number of exacerbations and improves the quality of life (QoL). The objective of this study was to evaluate the cost-effectiveness of reslizumab. METHODS: A Markov model was used to compare the cost-effectiveness of add-on reslizumab with the standard-of-care (SOC) from the US societal perspective over a five-year time horizon...
August 29, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972658/respiratory-waveform-variation-can-prevent-pulsus-paradoxus-measurement-by-sphygmomanometry
#12
Jonas Alexander Pologe, Kara Lynn Wolley, Donald H Arnold
BACKGROUND: Pulsus paradoxus (PP) represents increased fluctuation of systolic pressure during the respiratory cycle. PP increases in pathologic conditions, including asthma and other obstructive airways diseases. Respiratory waveform variation (RWV) represents arterial-waveform baseline variability resulting from intra-pleural pressure changes during the respiratory cycle in the presence of airway obstruction. It is not known whether RWV influences manual PP measurement using a sphygmomanometer and stethoscope...
August 29, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30073876/associations-between-asthma-trigger-reports-mental-health-conditions-and-asthma-morbidity-among-world-trade-center-rescue-and-recovery-workers
#13
E Morales-Raveendran, E Goodman, E West, J E Cone, C Katz, J Weiss, J M Feldman, D Harrison, S Markowitz, Alex Federman, J P Wisnivesky
AIM: There is limited information regarding asthma triggers in World Trade Center (WTC) rescue and recovery workers (RRW) or how mental health conditions affect the perception of triggers. METHODS: We included 372 WTC workers with asthma. The Asthma Trigger Inventory (ATI) assessed triggers along five domains: psychological, allergens, physical activity, infection, and pollution. We administered the Structured Clinical Interview to diagnose post-traumatic stress disorder (PTSD), major depression and panic disorder (PD)...
August 24, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972657/validation-of-fitness-tracker-for-sleep-measures-in-women-with-asthma
#14
Jessica Castner, Manoj J Mammen, Carla R Jungquist, Olivia Licata, John J Pender, Gregory E Wilding, Sanjay Sethi
OBJECTIVE: Nighttime wakening with asthma symptoms is a key to assessment and therapy decisions, with no gold standard objective measure. The study aims were to (1) determine the feasibility, (2) explore equivalence, and (3) test concordance of a consumer-based accelerometer with standard actigraphy for measurement of sleep patterns in women with asthma as an adjunct to self-report. METHODS: Panel study design of women with poorly controlled asthma from a university-affiliated primary care clinic system was used...
August 24, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972654/the-role-of-asthma-in-caries-occurrence-meta-analysis-and-meta-regression
#15
Bernardo Antonio Agostini, Kaue Farias Collares, Francine Dos Santos Costa, Marcos Britto Correa, Flavio Fernando Demarco
OBJECTIVE: We aimed to conduct a systematic review of the literature regarding the association between asthma and caries, assess the effect of asthma on the occurrence of caries in primary and permanent dentitions, and determine factors that could affect the estimates of this association. DATA SOURCE: We used the following databases: PubMed, Web of Science, SCOPUS, and LILACS/BVS, for the literature review. STUDY SELECTION: We included observational studies that investigated the association between asthma and dental caries, excluding studies with syndromic patients, literature reviews, case reports, and in vitro and in situ studies...
August 24, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972651/could-home-based-feno-measurements-breathe-new-life-into-asthma-management
#16
Trevor D Rapson, Graham L Hall, Tara D Sutherland
No abstract text is available yet for this article.
August 24, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972331/predictors-of-prior-asthma-specialist-care-among-pediatric-patients-seen-in-the-emergency-department-for-asthma
#17
Neha T Agnihotri, Kathryn H Pade, Sitaram Vangala, Lindsey R Thompson, Vincent J Wang, Sande O Okelo
BACKGROUND: Asthma guidelines recommend specialist care for patients experiencing poor asthma outcomes during emergency department (ED) visits. The prevalence and predictors of asthma specialist care among an ED population seeking pediatric asthma care are unknown. OBJECTIVE: To examine, in an ED population, factors associated with prior asthma specialist use based on parental reports of prior asthma morbidity and asthma care. METHODS: Parents of children ages 0 to 17 years seeking ED asthma care were surveyed regarding socio-demographics, asthma morbidity, asthma management and current asthma specialist care status...
August 24, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972330/paths-of-causal-influence-from-prenatal-inflammation-and-preterm-gestation-to-childhood-asthma-symptoms
#18
Nada Sindičić Dessardo, Elvira Mustać, Srdjan Banac, Sandro Dessardo
INTRODUCTION: Long-lasting respiratory symptoms have a huge impact on the quality of life in prematurely born children. The aim was to investigate paths of assumed causality leading from foetal inflammatory response syndrome (FIRS) to asthma symptoms in preterms. METHODS: Demographic, antenatal, delivery and outcome data were collected from 262 infants with less than 32 completed weeks of gestational age over a 10-year period in a prospective cohort study. The presence of symptoms of asthma beyond the age of 5 years was the primary outcome measure...
August 24, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972095/treatment-patterns-and-related-clinical-consequences-in-adults-with-asthma
#19
Piyameth Dilokthornsakul, Angela M Thompson, Jonathan D Campbell
OBJECTIVE: A stepwise therapeutic management is recommended for asthma patients by the Global Initiative for Asthma (GINA). Little is known about the recommendations applied in real world settings. This study aims to associate Treatment step with clinical events in patients with mild or severe asthma. METHODS: A retrospective claims database analysis included adult patients with mild (GINA step 1) or severe asthma (GINA step 4). Maximum Treatment Step was measured within the first and second 90-day period after index date (the first date of asthma diagnosis during the inclusion period)...
August 24, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29969926/filarial-tropical-pulmonary-eosinophilia-a-condition-masquerading-asthma-a-series-of-12-cases
#20
Wonashi R Tsanglao, Devki Nandan, Sudha Chandelia, Narendra Kumar Arya, Anu Sharma
INTRODUCTION: Tropical pulmonary eosinophilia (TPE) is a form of occult filariasis, clinically characterized by paroxysmal cough, wheezing and dyspnea which is often misdiagnosed and treated as asthma. These manifestations result from a host immune response to trapped antigens of the microfilarial parasites Wuchereria bancrofti or Brugia malayi in the pulmonary microcirculation. CASE STUDY: We describe three rare presentations of TPE (cor pumonale, cystic lung disease and respiratory distress mimicking acute severe asthma) in our series of 12 cases...
August 24, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
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