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Journal of Asthma: Official Journal of the Association for the Care of Asthma

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https://www.readbyqxmd.com/read/28075198/impact-of-a-history-of-maternal-depression-and-anxiety-on-asthma-control-during-pregnancy
#1
Luke E Grzeskowiak, Brian Smith, Anil Roy, K Oliver Schubert, Bernhard T Baune, Gustaaf A Dekker, Vicki L Clifton
OBJECTIVE: To determine the impact of self-reported maternal depression/anxiety on asthma control during pregnancy. METHOD: Pregnant women with a doctor diagnosis of asthma (n = 189) were prospectively recruited at their antenatal booking visit and the presence of maternal depression and anxiety was identified using self-report and routine questionnaire assessments. Data on exacerbations and asthma control were collected during gestation. Asthma control was assessed using the Juniper asthma control questionnaire and women were classified as having recurrent uncontrolled asthma if their ACQ score was > 1...
January 11, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28060556/the-frequency-of-sleep-disordered-breathing-in-children-with-asthma-and-its-effects-on-asthma-control
#2
Tayfur Ginis, Fatih Alper Akcan, Murat Capanoglu, Muge Toyran, Refika Ersu, Can Naci Kocabas, Ersoy Civelek
BACKGROUND: The presence of sleep-disordered breathing (SDB) in children with asthma may cause difficult to control asthma. OBJECTIVES: The aim of this study was to determine the frequency of SDB in children with asthma, to evaluate its effects on asthma control and to assess the risk factors associated with the presence of SDB. METHODS: Parents of children who Sleep Questionnaire (PSQ) and the Childhood Asthma Control Test (C-ACT). Asthma control level was assessed according to Global Initiative for Asthma (GINA)...
January 6, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28055281/effects-of-bronchoscopy-on-lung-function-in-asthmatics
#3
Christina Bellinger, Eugene R Bleecker, Stephen P Peters, Rodolfo M Pascual, Jeffrey Krings, Regina V Smith, Annette Hasties, Wendy C Moore
BACKGROUND: To better understand changes in pulmonary physiology related to asthma severity following bronchoscopy, we performed scheduled pre- and post-procedure spirometry on all subjects undergoing bronchoscopy in our research program. METHODS: Control subjects and asthma subjects of all severity were recruited for bronchoscopy. On the day of bronchoscopy, subjects underwent spirometry when they arrived, after pre-bronchoscopy treatment with albuterol and then up to three sets within two hours following completion of the bronchoscopy...
January 5, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28055280/spatiotemporal-patterns-of-childhood-asthma-hospitalization-and-utilization-in-memphis-metropolitan-area-from-2005-to-2015
#4
Tonny J Oyana, Pradeep Podila, Jagila Minso Wesley, Slawo M Lomnicki, Stephania A Cormier
OBJECTIVE: To identify key risk factors and explain spatiotemporal patterns of childhood asthma in the Memphis Metropolitan Area (MMA) over an 11-year period (2005 to 2015). We hypothesize that in the MMA region this burden is more prevalent among urban children living south, downtown, and north of Memphis than other areas. METHODS: We used a large-scale longitudinal electronic health record database from an integrated healthcare system, GIS, statistical, and space-time models to study spatiotemporal distributions of childhood asthma at census-tract level...
January 5, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28055276/quality-of-life-of-asthmatic-children-and-adolescents-portuguese-translation-adaptation-and-validation-of-the-questionnaire-pediatric-quality-of-life-pedsql-asthma-module
#5
Fernanda Pereira Monteiro, Dirceu Solé, Gustavo Falbo Wandalsen
OBJECTIVE: To translate, validate and verify the psychometric properties of the Portuguese version of the instrument "Pediatric Quality of Life Asthma Module" (PedsQL Asthma) culturally adapted for the Brazilian culture. METHODS: After being translated to Portuguese and culturally adapted, the questionnaire was answered by 200 asthmatic children and adolescents (ages 2 to 18) as well as the adults responsible for them. Validation required the use of the following instruments, PedsQL Asthma Children (applied to children and adolescents), PedsQL Asthma Parents (applied to adults responsible for children and adolescents), Pediatric Asthma Quality of Life (PAQLQ), Asthma Control Test (ACT) or Childhood Asthma Control Test (C-ACT), as well as socio-economic and personal information questionnaires...
January 5, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28055274/does-the-medical-diagnosis-of-occupational-asthma-coincide-with-the-legal-diagnosis
#6
Zeynep Çelebi Sözener, Ömür Aydın, Yavuz Selim Demirel, Şadan Soyyiğit, Pamir Çerçi, Reşat Kendirlinan, Sevim Bavbek, Gülfem Elif Çelik, Zeynep Mısırlıgil, Betül Ayşe Sin, Arif Keleşoğlu, Dilşad Mungan
Objective The incidence of occupational asthma(OA) is increasing worldwide. In this study, we first aimed to document the rate of diagnosis of OAamong patients who were referred to our clinic from Social Security Institution and factors that affected diagnosis, and secondly, we aimed to assess the consistency of the medical diagnosis and the legal diagnosis. Methods The study involved 132 consecutive patients who were referred to our clinic for evaluation of OA between 2010 and 2015. Detailed workplace history,the tools used in the diagnosis such as peak expiratory flow(PEF) monitoring and bronchial provocation tests and final medical diagnosis were recorded from case files...
January 5, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28055272/rs12603332-is-associated-with-male-asthma-patients-specifically-in-urban-areas-of-lahore-pakistan
#7
Muhammad Farooq Sabar, Mariam Shahid, Iqbal Bano, Muhammad Usman Ghani, Muhammad Akram, Farheena Iqbal, Samra Kousar, Zafar Iqbal, Saba Altaf, Tayyab Husnain
OBJECTIVE: rs12603332, an important regulatory site variant, is known to alter the regulatory motif E2A that is involved in maturation of B-lymphocytes. The study was designed to check whether different environmental exposures alter its risk allele association with asthma or not. METHODS: 200 Physician diagnosed asthma patients and 108 healthy individuals were enrolled from hospitals of Lahore. After quantitation of DNA extracted from their peripheral blood samples, amplification of genomic region with rs12603332 was performed followed by single base extension...
January 5, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28055271/airway-hyperresponsiveness-to-mannitol-and-methacholine-and-exhaled-nitric-oxide-in-children-with-asthma
#8
Young A Park, Hyun Bin Park, Yoon Hee Kim, In Sook Sul, Seo Hee Yoon, Hye Ran Kim, Kyung Won Kim, Kyu-Earn Kim, Myung Hyun Sohn
No abstract text is available yet for this article.
January 5, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28055270/takotsubo-cardiomyopathy-a-known-unknown-foe-of-asthma
#9
Ourania S Kotsiou, Alexandros Douras, Demosthenes Makris, Nikoleta Mpaka, Konstantinos I Gourgoulianis
INTRODUCTION: Patients with uncontrolled asthma are at a greater risk of asthma attacks requiring emergency room visits or hospital admissions. Takotsubo cardiomyopathy is potentially a significant complication in a course of status asthmaticus. CASE STUDY: We present a 43-year-old female patient who presented with status asthmaticus further complicated with takotsubo cardiomyopathy. RESULTS: Recognizing apical ballooning syndrome is challenging in patients with a history of respiratory disease because the symptoms of the last entity may complicate the diagnostic approach...
January 5, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28055268/perceptions-about-interpersonal-relationships-and-school-environment-among-middle-school-students-with-asthma
#10
Hyekyun Rhee, Brenda McQuillan, Ding-Geng Chen, Shannska Atis
OBJECTIVES: To examine interpersonal relationships involving peers and teachers and perceptions about school environment among middle school students with asthma in comparison to their healthy counterparts. The study also assesses asthma prevalence in a large sample of middle school students representing different geographic locations. METHODS: Cross-sectional data were collected from 1059 middle school students in grades 6-8 enrolled in schools in a northeastern region of the U...
January 5, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28045551/use-of-a-low-literacy-written-action-plan-to-improve-parent-understanding-of-pediatric-asthma-management-a-randomized-controlled-study
#11
Hsiang Shonna Yin, Ruchi Gupta, Alan L Mendelsohn, Benard P Dreyer, Linda van Schaick, Christina R Brown, Karen Encalada, Dayana Sanchez, Christopher Warren, Suzy Tomopoulos
OBJECTIVES: To determine whether parents who use a low literacy, pictogram- and photograph-based written asthma action plan have a better understanding of child asthma management compared to parents using a standard plan. METHODS: Randomized controlled study in 2 urban pediatric outpatient clinics. INCLUSION CRITERIA: English/Spanish-speaking parents of 2-12 year old asthmatic children. Parents were randomized to receive a low literacy or standard asthma action plan (American Academy of Allergy, Asthma and Immunology) for a hypothetical patient on controller and rescue medications...
January 3, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28001469/a-cross-sectional-assessment-of-the-prevalence-and-burden-of-mild-asthma-in-urban-china-using-the-2010-2012-and-2013-china-national-health-and-wellness-surveys
#12
Bo Ding, Marco DiBonaventura, Niklas Karlsson, Xia Ling
OBJECTIVE: To estimate the prevalence of mild asthma in urban China and to measure the association between asthma severity and quality of life (QOL), work productivity, and healthcare resource use. METHODS: Data were from the China National Health and Wellness Surveys (NHWS) conducted between 2010 and 2013 (N = 59,935), Internet-based surveys of adults in urban China. Patients were categorized by asthma severity according to self-report and Global Initiative for Asthma (GINA2014) guidelines via self-reported medication use (mild [GINA 1-2] vs moderate/severe [GINA 3-4])...
December 21, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27929704/impact-of-holding-position-during-inhalation-on-drug-release-from-a-reservoir-a-blister-and-a-capsule-type-dry-powder-inhaler
#13
Tetsuri Kondo, Toshimori Tanigaki, Haruko Yokoyama, Makoto Hibino, Sakurako Tajiri, Kenichro Akazawa, Yasuhiko Yamada, Stanley M Cassan
OBJECTIVE: To determine whether drug release may be impaired by tilting some dry powder inhalers (DPIs). METHODS: Using an inhalation simulator, we measured drug release from Turbuhaler® (TBH), Diskus® (DKS) and Breezhaler® (BZH) at several peak inhaled flow rates (PIFs) while the DPIs were held level and tilted (80 degrees). Drug release was then measured from all three DPI's at 0, 30, 60 and 90 degrees of tilt, and capsule rotation was also recorded. RESULTS: Drug release from TBH was flow-dependent while that from DKS and BZH was flow-independent...
December 8, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27929698/breastfeeding-associated-with-higher-lung-function-in-african-american-youths-with-asthma
#14
Sam Oh, Randal Du, Andrew M Zeiger, Meghan E Mcgarry, Donglei Hu, Neeta Thakur, Maria Pino-Yanes, Joshua M Galanter, Harold J Farber, Celeste Eng, Katherine Keiko Nishimura, Scott Huntsman, Kelley Meade, Pedro Avila, Denise Serebrisky, Kirsten Bibbins-Domingo, Michael A Lenoir, Jean G Ford, Emerita Brigino-Buenaventura, William Rodriguez-Cintron, Shannon M Thyne, Saunak Sen, Jose R Rodriguez-Santana, Keoki Williams, Rajesh Kumar, Esteban G Burchard
Objective In the United States, Puerto Ricans and African Americans have lower prevalence of breastfeeding and worse clinical outcomes for asthma compared with other racial/ethnic groups. We hypothesize that history of breastfeeding is associated with increased forced expiratory volume in 1 second (FEV1) % predicted and reduced asthma exacerbations in Latino and African American youths with asthma. Methods As part of Study A and Study B, we conducted case-only analyses in children and adolescents aged 8-21 years old with asthma from four different racial/ethnic groups: African Americans (n = 426), Mexican Americans (n = 424), mixed/other Latinos (n = 255), and Puerto Ricans (n = 629)...
December 8, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27929695/secondhand-smoke-exposure-illness-severity-and-resource-utilization-in-pediatric-emergency-department-patients-with-respiratory-illnesses
#15
Ashley L Merianos, Cinnamon A Dixon, E Melinda Mahabee-Gittens
OBJECTIVE: Hospital-based data reveal that children who have secondhand smoke exposure (SHSe) experience severe respiratory illnesses and greater resource utilization. Our objective was to assess the relationship between SHSe and illness severity/resource utilization among children presenting to the pediatric emergency department (PED) with three common respiratory conditions - asthma, bronchiolitis, and pneumonia. METHODS: A retrospective review of a yearlong consecutive sample of PED patients with SHSe status documentation and asthma, bronchiolitis, or pneumonia diagnoses was performed...
December 8, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27929694/dna-methylation-levels-associate-with-race-and-childhood-asthma-severity
#16
Marcia A Chan, Christina E Ciaccio, Nicole M Gigliotti, Mo Rezaiekhaligh, Jacob A Siedlik, Kevin Kennedy, Charles S Barnes
OBJECTIVE: Asthma is a common chronic childhood disease worldwide. Socioeconomic status, genetic predisposition and environmental factors contribute to its incidence and severity. A disproportionate number of children with asthma are economically disadvantaged and live in substandard housing with potential indoor environmental exposures such as cockroaches, dust mites, rodents and molds. These exposures may manifest through epigenetic mechanisms that can lead to changes in relevant gene expression...
December 8, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27929691/association-between-pediatric-home-management-plan-of-care-compliance-and-asthma-readmission
#17
Ronen Zipkin, Sheree M Schrager, Eugene Nguyen, Mary Rose Mamey, Ingrid Banuelos, Susan Wu
OBJECTIVES: In 2007, The Joint Commission implemented three children's asthma care (CAC) measures to help improve the quality of care for patients admitted with asthma. Due to lack of consistent evidence showing a relationship between home management plan of care (HMPC) compliance and readmission rates, CAC-3 was retired in 2016. We aimed to understand the relationship between HMPC compliance and revisits to the hospital, and investigate which components of the HMPC, if any, were driving the effect...
December 8, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27929685/respiratory-comorbidities-cannot-be-neglected
#18
Fa-Ping Wang, Hui Mao
No abstract text is available yet for this article.
December 8, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27905842/airway-smooth-muscle-cells-from-ovalbumin-sensitized-mice-show-increased-proliferative-response-to-tgf%C3%AE-1-due-to-up-regulation-of-smad3-and-tgf%C3%AE-rii
#19
Jianting Shi, Ming Chen, Lihua Ouyang, Linjie Huang, Xiaoling Lin, Wei Zhang, Ruiyun Liang, Zhiqiang Lv, Shanying Liu, Shanping Jiang
Transforming growth factor (TGF)-β1 is an important cytokine in airway remodeling in asthma. However, results of studies focusing on the effect of TGFβ1 on proliferation of airway smooth muscle cells (ASMCs) are controversial. This study aimed to elucidate the role of TGFβ1 signaling in the proliferation of ASMCs by establishing an allergic model that mimics airway remodeling in chronic asthma and cell culture. Cell proliferation was detected by viable cell counting and Cell Counting Kit (CCK)-8 analysis...
December 1, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27905829/post-traumatic-stress-disorder-dimensions-and-asthma-morbidity-in-world-trade-center-rescue-and-recovery-workers
#20
Irina Mindlis, Esperanza Morales-Raveendran, Emily Goodman, Kevin Xu, Clara Vila-Castelar, Kristine Keller, Ginger Crawford, Shynah James, Craig Katz, Laura E Crowley, Rafael E de la Hoz, Steven Markowitz, Juan P Wisnivesky
Objective Using data from a cohort of World Trade Center (WTC) rescue and recovery workers with asthma, we assessed whether meeting criteria for post-traumatic stress disorder (PTSD), sub- PTSD and for specific PTSD symptom dimensions are associated with increased asthma morbidity. Methods Participants underwent a Structured Clinical Interview for Diagnostic and Statistical Manual to assess presence of PTSD following DSM-IV criteria during in-person interviews between December 2013 and April 2015. We defined sub-threshold PTSD as meeting criteria for two of three symptom dimensions: re-experiencing, avoidance, or hyper-arousal...
December 1, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
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