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Journal of Asthma: Official Journal of the Association for the Care of Asthma

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https://www.readbyqxmd.com/read/30426824/chest-tightness-is-relieved-with-the-use-of-asthma-drugs-except-bronchodilators
#1
Hirokazu Taniguchi, Yuko Nakanishi, Takeshi Tsuda, Yasuaki Masaki, Hideaki Furuse, Kensuke Suzuki, Shin Ishizawa, Atsushi Muto, Mami Shimizu, Tomomi Ichikawa, Hideki Miyazawa
OBJECTIVE: Many patients with a chief complaint of chest tightness are examined in medical facilities, and a lack of diagnosis is not uncommon. We have reported that these patients often include those with chest tightness relieved with bronchodilator use (CTRB) and those with chest tightness relieved with the use of asthma drugs except bronchodilators (CTRAEB). The purpose of this study was to demonstrate the clinical characteristics of the patients with CTRAEB and compare them with data from patients with CTRB...
November 14, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30407087/validity-and-the-reliability-of-the-turkish-version-of-the-control-of-allergic-rhinitis-and-asthma-test-for-children-caratkids
#2
Sehra Birgül Batmaz, Sibel Alicura Tokgöz, Joao A Fonseca
AIM: Asthma occurs in association with allergic rhinitis. Control of Allergic Rhinitis and Asthma Test for Children (CARATKids) is a questionnaire to assess control of both diseases. The aim of this study was to assess the validity and reliability of the CARATKids in Turkish children aged 6-12 years. METHODS: After a cultural adaptation process, children with asthma and allergic rhinitis were recruited. CARATKids, childhood Asthma Control Test, total nasal symptom score, visual analog scale scores for asthma and rhinitis, peak nasal inspiratory flow and peak expiratory flow values were obtained at baseline and after 4-6 weeks...
November 8, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30395756/vitamin-d-supplementation-during-pregnancy-and-the-risk-of-wheezing-in-offspring-a-systematic-review-and-dose-response-meta-analysis
#3
Wen Li, Zhong Qin, Jie Gao, Zhibin Jiang, Yihui Chai, Liancheng Guan, Yuhong Ge, Yunzhi Chen
BACKGROUND: In the past few years, growing evidence supports a preventive role of vitamin D supplementation during pregnancy for wheezing or asthma in offspring. However, the optimal dose of vitamin D intake is unclear. We conducted a meta-analysis to examine the linear and nonlinear dose-response pattern of vitamin D intake during pregnancy and asthma or wheezing in offspring. QUESTIONS/PURPOSES: The purpose of this study was to answer the following question: Which dose of vitamin D is more effective in preventing wheezing in offspring? METHOD: We identified relevant studies by searching PubMed, EMBASE and CENTRAL up to December 2017 and by hand-searching reference lists...
November 5, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30395749/parent-experiences-with-a-nurse-supervised-community-health-worker-asthma-home-visiting-program
#4
Rebecca E Penzias, Virginia Sanabia, Urmi Bhaumik, Susan J Sommer, Kyra M Shreeve, Elizabeth R Woods
OBJECTIVE: This study seeks to identify helpful components of a nurse-supervised Community Health Worker (CHW) asthma home-visiting program, obtain feedback from parents and families about their experiences, and receive suggestions for new services that the program could provide. METHODS: Likert scale ratings and semi-structured qualitative interviews were conducted with parents who were selected from a representative sample and previously participated in the program...
November 5, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30395748/cross-sectional-survey-study-to-examine-underuse-of-twice-daily-inhaled-maintenance-therapy-among-patients-with-asthma
#5
Richard H Stanford, Chris Bell, Arpita Nag, Phaedra T Johnson, Michael P Johnson, Angela Watkins
OBJECTIVE: Anecdotal evidence suggests that some patients with asthma intentionally use their twice-daily (BID) inhaled controller therapy once daily (QD), thus not achieving optimal dosing levels. This study identified the prevalence of and factors associated with intentional QD use of BID-indicated controllers among adult patients with asthma. METHODS: This was a cross-sectional survey study of adults using inhaled controllers intended for BID dosing for treatment of asthma and/or COPD...
November 5, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30395745/infographics-or-video-which-one-is-more-effective-in-asthmatic-patients-health-a-randomized-clinical-trial
#6
Maryam Ebrahimabadi, Korosh Rezaei, Abdollatif Moini, Andrew Fournier, Ahmadreza Abedi
OBJECTIVE: Asthma disease is a complex medical condition for which the control of symptoms depends on sufficient patient knowledge, self-care, and adherence to medication protocols. Researchers conducted this study to evaluate the impact of infographics and video on asthma patients' adherence to medication. METHODS: A randomized clinical trial in which 80 asthmatics were enrolled and allocated to two study groups (infographic and video groups). Researchers used questionnaires to gather demographic data...
November 5, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30395744/the-characterization-of-asthma-with-blood-eosinophilia-in-adults-in-latin-america
#7
Martín Bedolla-Barajas, José Raúl Ortiz-Peregrina, Dante Daniel Hernández-Colín, Jaime Morales-Romero, Tonatiuh Ramses Bedolla-Pulido, Désirée Larenas-Linnemann
OBJECTIVE: To identify and characterize asthma with blood eosinophilia in adults. METHODS: This cross-sectional study consisted of 164 asthma patients, aged 18 years or older. Multivariate analyses by logistic regression were performed to identify clinical characteristics and biomarkers associated with asthma with blood eosinophilia (defined as asthma and a peripheral blood eosinophil count ≥400 cells/mm3 ). To evaluate the diagnostic accuracy of these biomarkers, the sensitivity, specificity and predictive values were calculated...
November 5, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30395734/favorable-response-to-asthma-dosed-subcutaneous-mepolizumab-in-eosinophilic-pneumonia
#8
Robert Y Lin, Toni P Santiago, Nina M Patel
INTRODUCTION: Mepolizumab targets eosinophils in the treatment of asthma. The dose used for asthma is considerably lower than that used for treating eosinophilic granulomatosis with polyangiitis, a recently approved indication. While intravenous mepolizumab use has reported utility in non-asthma eosinophilic disorders, the efficacy of the subcutaneous asthma dosing of the drug for eosinophilic pneumonia is not known. CASE STUDY: A middle-aged female was diagnosed with eosinophilic pneumonia...
November 5, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30380955/serum-vitamin-a-zinc-and-visual-function-in-children-with-moderate-to-severe-persistent-asthma
#9
Diana Andino, James Moy, Bruce I Gaynes
BACKGROUND: Asthma is a common childhood disorder with complex pathobiologic components that may include aspects of nutritional deficit. The contribution of vitamin deficiency, specifically vitamin A, as part of the disease complex has not been well studied, particularly among at risk children. In this study, we examined the prevalence of vitamin A as well as zinc deficiency in conjunction with visual function among an urban pediatric population sample with moderate-severe persistent asthma...
October 31, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30376385/student-perspectives-on-asthma-management-in-schools-a-mixed-methods-study-examining-experiences-facilitators-and-barriers-to-care
#10
Julia Naman, Valerie G Press, Dagny Vaughn, Ashley Hull, Kim Erwin, Anna Volerman
OBJECTIVE: Children spend nearly a third of their day at school, making it a critical point of intervention for those with asthma. This study aimed to illuminate minority students' experiences with asthma at school and perceptions of facilitators and barriers to care. METHODS: A mixed-methods study was conducted with elementary students with asthma. Participants completed a 24-question survey, drawing exercise to depict experiences caring for their asthma at school, and focus group discussion...
October 30, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30365368/the-asthma-symptom-free-days-questionnaire-how-reliable-are-patient-responses
#11
Barbara P Yawn, Elliot Israel, Michael E Wechsler, Wilson Pace, Suzanne Madison, Brian Manning, Gheorghe Doros, Anne Fuhlbrigge
OBJECTIVE: Symptom free days are a widely used patient-reported outcome (PRO) in asthma clinical trials. We assessed the internal consistency of one instrument for this PRO, the Symptom Free Days Questionnaire (SFDQ), in a population of Black adults with asthma enrolled in the Blacks and Exacerbations on Long-acting beta agonists and Tiotropium (BELT) trial. METHODS: We assessed responses to the SFDQ collected at baseline, 6 and 12 months as part of the BELT trial...
October 26, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30365346/gaps-in-health-insurance-coverage-and-emergency-department-use-among-children-with-asthma
#12
Courtney Gushue, Rebecca Miller, Shahid Sheikh, Elizabeth D Allen, Joseph D Tobias, Don Hayes, Dmitry Tumin
BACKGROUND: Gaps in health insurance coverage may complicate asthma management and increase emergency department (ED) use. Using two nationally-representative surveys, we characterize the prevalence of coverage gaps among children with asthma, and describe their association with ED visits in this population. METHODS: De-identified data were obtained from the 2016 National Survey of Children's Health (NSCH) and National Health Interview Survey (NHIS). Among children with asthma, we classified coverage over the past year as: (1) continuous private, (2) continuous public, (3) gap in coverage, and (4) continuously uninsured...
October 26, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30359154/characteristics-of-asthma-and-copd-overlap-syndrome-acos-in-the-canadian-population
#13
Ambikaipakan Senthilselvan, Jeremy Beach
OBJECTIVE: Asthma is a chronic disease affecting both children and adults, whereas chronic obstructive pulmonary disease (COPD) is a respiratory disease most commonly related to smoking and is usually seen in adults. When the airway disease shares features of both asthma and COPD, the phenotype is referred to as asthma and COPD overlap syndrome (ACOS). The objective of this cross-sectional study is to characterize ACOS in the Canadian population. METHODS: Data from the first three cycles of the Canadian Health Measures Survey (CHMS) were used in this study...
October 25, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30359153/validation-of-the-st-george-s-respiratory-questionnaire-and-risks-factors-affecting-the-quality-of-life-of-lebanese-copd-and-asthma-patients
#14
Zeina Akiki, Souheil Hallit, Nelly Layoun, Michelle Cherfane, Hala Sacre, Mirna Waked, Pascale Salameh
OBJECTIVE: We aimed to validate the Arabic version of the St George's Respiratory Questionnaire (SGRQ) for use in Lebanese Chronic obstructive pulmonary disease (COPD) and asthma patients and to identify risk factors that might affect the quality of life in these patients. METHODS: COPD (n = 90) and asthma patients (n = 124) were recruited from the outpatient clinics of the Pulmonology department of a university hospital and a medical center in Beirut. They filled out a standardized questionnaire...
October 25, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30359144/the-efficacy-and-safety-of-different-long-acting-%C3%AE-2-agonists-combined-with-inhaled-glucocorticoid-regimens-in-patients-with-asthma-a-network-meta-analysis
#15
Ying Tang, Caiyun Zhang, Zhigang Zhang, Jinhui Tian
OBJECTIVE: To determine the efficacy and safety of current maintenance therapies consisting of different regimens of long-acting β2-agonists (LABA) with inhaled corticosteroids (ICS) in patients with asthma. METHODS: A network meta-analysis (NMA) was conducted after a comprehensive search for relevant studies in the PubMed, Cochrane Library, and Embase databases up to January 1, 2017. Randomized clinical trials comparing LABA combined with ICS in patients with asthma were selected...
October 25, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30359141/the-association-between-pollutant-levels-and-asthma-related-emergency-department-visits-in-the-bronx-after-the-world-trade-center-attacks
#16
Kunwar Ishan Sharma, Ryan Abraham, Wenzhu Mowrey, Jennifer Toh, David Rosenstreich, Sunit Jariwala
OBJECTIVE: To examine the potential impact of the World Trade Center (WTC) attacks on asthma-related emergency department visits (AREDV) in the New York City borough of the Bronx. METHODS: We obtained daily nitrogen dioxide (NO2 ), sulfur dioxide (SO2 ) and ozone (O3 ) values from the National Climatic Data Center's collection station in the Bronx from 1999 and 2002, a year before and after the WTC attacks. We compared daily AREDV and pollutant levels between 1999 and 2002 using the Wilcoxon signed rank sum test...
October 25, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30335533/difference-between-two-exhaled-nitric-oxide-analyzers-niox-vero-%C3%A2-electrochemical-hand-held-analyzer-and-noa280i-%C3%A2-chemiluminescence-stationary-analyzer
#17
Yuki Tanabe, Norihiro Harada, Jun Ito, Kei Matsuno, Tomohito Takeshige, Sonoko Harada, Mirano Takemasa, Masaki Kotajima, Ayako Ishimori, Yoko Katsura, Fumihiko Makino, Ryo Atsuta, Kazuhisa Takahashi
BACKGROUND: Fractional exhaled nitric oxide (FENO ) is useful for the evaluation of eosinophilic airway inflammation, including that seen in asthma. Although a new electrochemical hand-held FENO analyzer, the NIOX VERO® (Aerocrine AB, Solna, Sweden), is clinically convenient to use, it has not been fully compared with the chemiluminescence stationary electrochemical analyzer NOA280i® (Sievers Instruments, Boulder, CO, USA) in terms of the level of measured FENO . The aim of this study was to determine whether there is a difference between the two analyzers...
October 18, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30335531/psychopathology-health-related-quality-of-life-and-parental-attitudes-in-pediatric-asthma
#18
Hicran Doğru, Aslı Sürer-Adanır, Esin Özatalay
OBJECTIVE: Considering that unknown psychopathology might play a role in the management of pediatric asthma, this study examines how self-esteem and psychosocial family environment (child-raising attitudes and parental coping strategies) influence the physical and psychosocial well-being of these children. Hence, this paper aims to predict psychosocial factors influencing health-related quality-of-life (HRQL) in children with asthma without a documented history of mental illness. METHODS: 32 patients with asthma and 32 controls aged 8-18 years were included in the study...
October 18, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30130418/effects-of-systemic-corticosteroids-on-blood-eosinophil-counts-in-asthma-real-world-data
#19
Hector Ortega, Jean-Pierre Llanos, Marie-Helene Lafeuille, Mei Sheng Duh, Guillaume Germain, Dominique Lejeune, Susan Sama, Chris Bell, Beth Hahn
INTRODUCTION: Systemic corticosteroids (SCS) are effective anti-inflammatory therapies for patients with severe or persistent asthma. Use of SCS reduces blood eosinophil counts; the magnitude and duration of reduction in real-world settings needs further investigation. OBJECTIVE: To examine the SCS effect on blood eosinophil counts over time among patients with asthma in a real-world setting. METHODS: This retrospective study used Reliant Medical Group (Worcester, MA) electronic medical records between January 2011 and December 2015...
October 16, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30015531/combining-pharmacy-expertise-with-asthma-educator-certification-assessing-the-impact-on-inner-city-asthma-patients
#20
Teresa George Abraham, Charnicia Huggins, Gilda Diaz-Fuentes, John Roglieri
OBJECTIVE: Asthma is one of the major causes of hospital readmissions in the South Bronx. The goal of this study was to assess the impact of asthma education provided by registered pharmacists with asthma educator certification (AE-C), on medication adherence and hospitalizations/Emergency Department (ED) visits. METHODS: This was a retrospective chart review of patients seen in the pulmonary clinic from October 2014 to August 2015 for asthma education by AE-C pharmacists...
October 16, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
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