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Journal of Asthma: Official Journal of the Association for the Care of Asthma

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https://www.readbyqxmd.com/read/30003851/a-pilot-randomized-controlled-trial-on-the-impact-of-text-messaging-check-ins-and-a-web-based-asthma-action-plan-versus-a-written-action-plan-on-asthma-exacerbations
#1
Iraj Poureslami, Jessica Shum, Richard T Lester, Hamid Tavakoli, Delbert R Dorscheid, J Mark FitzGerald
OBJECTIVE: We compared electronic asthma action plans (eAAP) supported by automated text messaging service (SMS) with written asthma action plans (AAP) on assessing acceptability and asthma control improvement. We hypothesized that the patients in eAAP group would have more improvements in their quality of life, asthma control, and decreased asthma exacerbations. METHODS: Patients with physician-diagnosed asthma having at least one asthma exacerbation in the previous 12 months were recruited...
July 13, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30003833/a-cost-effectiveness-analysis-of-reslizumab-in-the-treatment-of-poorly-controlled-eosinophilic-asthma
#2
Jenny Lam, Joel Hay, Jonathan Salcedo, Nicholas J Kenyon
INTRODUCTION: Poorly controlled severe eosinophilic asthma is difficult and costly to manage. Reslizumab, an add-on treatment for adults with severe eosinophilic asthma, reduces the number of exacerbations and improves the quality-of-life (QoL). The objective of this study was to evaluate the cost-effectiveness of reslizumab. METHODS: A Markov model was used to compare the cost-effectiveness of add-on reslizumab with the standard-of-care from the US societal perspective over a 5-year time horizon...
July 13, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/30003827/economic-impact-of-severe-asthma-in-spain-multicentre-observational-longitudinal-study
#3
Carlos Melero, Santiago Quirce, Alicia Huerta, Estefany Uría, Maribel Cuesta
OBJECTIVE: Estimate the economic impact of severe asthma from the Spanish social perspective through the estimation of the associated annual direct and indirect costs. METHODS: Observational, longitudinal, retrospective study carried out in 20 Spanish secondary settings (Pulmonology and Allergy Services) among patients aged ≥18, diagnosed with severe asthma according to ERS/ATS consensus and who have not experienced an exacerbation in the previous 2 months. Asthma-related healthcare resource utilization as well as asthma-related days off work were collected over a retrospective 12-month period from medical records review (inclusion period: June to November 2016)...
July 13, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29985718/self-management-behaviors-in-world-trade-center-rescue-and-recovery-workers-with-asthma
#4
Belen Rojano, Erin West, Emily Goodman, Jeffrey J Weiss, Rafael E de la Hoz, Michael Crane, Laura Crowley, Denise Harrison, Steven Markowitz, Juan P Wisnivesky
BACKGROUND: Asthma is a major source of morbidity among World Trade Center (WTC) rescue and recovery workers. While physical and mental health comorbidities have been associated with poor asthma control, the potential role and determinants of adherence to self-management behaviors (SMB) among WTC rescue and recovery workers is unknown. OBJECTIVES: To identify modifiable determinants of adherence to asthma self-management behaviors in WTC rescue and recovery worker that could be potential targets for future interventions...
July 9, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29985684/tolerance-to-exposure-to-essential-oils-in-patients-with-allergic-asthma
#5
Jean Levy, Catherine Neukirch, Isabelle Larfi, Pascal Demoly, Gabriel Thabut
BACKGROUND: Essential oils are volatile compounds of plant origin increasingly used by allergic and/or asthmatic subjects to purify indoor air. The active compounds of essential oils belong to terpenes, the most widespread biogenic volatile organic compounds (VOC). Although there is substantial literature showing associations between exposure to chemical VOCs and asthmatic symptoms and impaired respiratory function, the impact of essential oils in patients with asthma has never been studied...
July 9, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29985082/enhanced-pause-correlates-with-airway-neutrophils-and-airway-epithelial-injury-in-in-asthmatic-mice-treated-with-dexamethasone
#6
Chao Niu, Ting Wang, Wenjing Zou, Hu Jie, Linyan Ying, Mingxiang Zhang, Jingyue Liu, Daiyin Tian, Jihong Dai, Zhengxiu Luo, Enmei Liu, Lin Zou, Yi Xiong, Zhou Fu
OBJECTIVE: To investigate the correlations among airway inflammation, airway epithelial injury and airway hyperresponsiveness (AHR) in asthmatic mice treated with dexamethasone. METHODS: Female BALB/c mice were sensitized with intraperitoneal and hypodermic injections of ovalbumin (OVA) and aluminum on days 0, 7 and 14, challenged with OVA starting on day 21 for 10 days, and treated with dexamethasone via intraperitoneal injection starting on day 28 for 3 days. Female C57BL/6 mice were intranasally with house dust mite (HDM) on days 1 and 14, challenged intranasally with HDM on days 21, 23, 25, 27 and 29, and treated with sivelestat (a selective neutrophil elastase inhibitor) via intraperitoneal injection after each challenge...
July 8, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29984589/the-impact-of-traditional-literacy-and-education-on-health-literacy-in-adolescents-with-asthma
#7
Desha M Jordan, Jeana S Bush, Dennis R Ownby, Jennifer L Waller, Martha S Tingen
INTRODUCTION: People with low health literacy have poorer self-management of chronic diseases like asthma. Studies of parent health literacy and education level on the management of children's chronic illnesses reveal inconclusive results. We hypothesized a correlation between parent and adolescent health literacy in teens with asthma. METHODS: Sociodemographic data was obtained; health literacy was assessed on adolescents and parents with three instruments: REALM (Rapid Estimate of Adolescent/Adult Literacy in Medicine), SILS (Single Item Literacy Screener) and NVS (Newest Vital Sign)...
July 8, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972658/respiratory-waveform-variation-can-prevent-pulsus-paradoxus-measurement-by-sphygmomanometry
#8
Jonas Alexander Pologe, Kara Lynn Wolley, Donald Hayes Arnold
BACKGROUND: Pulsus paradoxus (PP) represents increased fluctuation of systolic pressure during the respiratory cycle. PP increases in pathologic conditions, including asthma and other obstructive airways diseases. Respiratory waveform variation (RWV) represents arterial-waveform baseline variability resulting from intra-pleural pressure changes during the respiratory cycle in the presence of airway obstruction. It is not known whether RWV influences manual PP measurement using a sphygmomanometer and stethoscope...
July 4, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972657/validation-of-fitness-tracker-for-sleep-measures-in-women-with-asthma
#9
Jessica Castner, Manoj J Mammen, Carla Jungquist, Olivia Licata, John J Pender, Gregory E Wilding, Sanjay Sethi
OBJECTIVE: Night-time wakening with asthma symptoms is key to assessment and therapy decisions, with no gold standard objective measure. The study aims were to 1) determine the feasibility, 2) explore equivalence, and 3) test concordance of a consumer-based accelerometer with standard actigraphy for measurement of sleep patterns in women with asthma as an adjunct to self-report. METHODS: Panel study design of women with poorly controlled asthma from a university-affiliated primary care clinic system was used...
July 4, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972654/the-role-of-asthma-in-caries-occurrence-meta-analysis-and-meta-regression
#10
Bernardo Antonio Agostini, Kaue Farias Collares, Francine Dos Santos Costa, Marcos Britto Correa, Flavio Fernando Demarco
OBJECTIVE: We aimed to conduct a systematic review of the literature regarding the association between asthma and caries, assess the effect of asthma on the occurrence of caries in primary and permanent dentitions, and determine factors that could affect the estimates of this association. DATA SOURCE: We used the following databases: PubMed, Web of Science, SCOPUS, and LILACS/BVS, for the literature review. STUDY SELECTION: We included observational studies that investigated the association between asthma and dental caries, excluding studies with syndromic patients, literature reviews, case reports, and in vitro and in situ studies...
July 4, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972652/depression-symptoms-and-quality-of-life-among-individuals-with-aspirin-exacerbated-respiratory-disease
#11
Jonathan M Feldman, Ariel E Zeigler, Krista Nelson, Esperanza Morales-Raveendran, Teresa Pelletier, Gigia Roizen Gottlieb, Zhen Ren, Elina Jerschow
OBJECTIVE: Patients with aspirin-exacerbated respiratory disease (AERD) have high disease burden due to the severity of asthma and sinonasal symptoms. There is limited research on the psychological well-being and subjective experiences of patients with AERD. This study examined levels of depression symptoms, asthma-related quality of life, and asthma control among AERD patients. METHODS: Thirty-two adults with AERD and 39 patients without AERD (asthma-only) were recruited from outpatient asthma/allergy clinics...
July 4, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972651/could-home-based-feno-measurements-breathe-new-life-into-asthma-management
#12
Trevor D Rapson, Graham L Hall, Tara D Sutherland
No abstract text is available yet for this article.
July 4, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972339/exploring-the-barriers-and-incentive-architecture-for-modifying-smoke-exposures-among-asthmatics
#13
Craig Tower, Arlene Butz, Cassia Lewis-Land, Meng Zhu, Mandeep S Jassal
BACKGROUND: The socio-structural barriers for reducing secondhand smoke exposure (SHSe) among children with asthma may be insurmountable for low-income caregivers. Health promoting financial incentives (HPFIs) are increasingly being used in the adult population to motivate and sustain tobacco-reduction behaviors. We assessed barriers to SHSe reduction and means to overcome them through the design of an HPFI-based, caregiver-targeted SHSe reduction study. METHODS: Using a mixed-methods design, we conducted semi-structured in-depth interviews among low-income primary caregivers of children with asthma residing in Baltimore City...
July 4, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972331/predictors-of-prior-asthma-specialist-care-among-pediatric-patients-seen-in-the-emergency-department-for-asthma
#14
N Agnihotri, K H Pade, S Vangala, L R Thompson, V J Wang, S O Okelo
BACKGROUND: Asthma guidelines recommend specialist care for patients experiencing poor asthma outcomes during emergency department (ED) visits. The prevalence and predictors of asthma specialist care among an ED population seeking pediatric asthma care are unknown. OBJECTIVE: To examine, in an ED population, factors associated with prior asthma specialist use based on parental reports of prior asthma morbidity and asthma care. METHODS: Parents of children ages 0 to 17 years seeking ED asthma care were surveyed regarding socio-demographics, asthma morbidity, asthma management, and current asthma specialist care status...
July 4, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972330/paths-of-causal-influence-from-prenatal-inflammation-and-preterm-gestation-to-childhood-asthma-symptoms
#15
Nada Sindičić Dessardo, Elvira Mustać, Srdjan Banac, Sandro Dessardo
Introduction; Long-lasting respiratory symptoms have a huge impact on the quality of life in prematurely born children.The aim was to investigate paths of assumed causality leading from Foetal Inflammatory Response Syndrome to asthma symptoms in preterms. Methods; Demographic, antenatal, delivery and outcome data were collected from 262 infants with less than 32 completed weeks of gestational age over a 10-year period in a prospective cohort study. The presence of symptoms of asthma beyond the age of 5 years was the primary outcome measure...
July 4, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972095/treatment-patterns-and-related-clinical-consequences-in-adults-with-asthma
#16
Piyameth Dilokthornsakul, Angela M Thompson, Jonathan D Campbell
OBJECTIVE: A stepwise therapeutic management is recommended for asthma patients by the Global Initiative for Asthma (GINA). Little is known about the recommendations applied in real world settings. This study aims to associate Treatment Step with clinical events in patients with mild or severe asthma. METHODS: A retrospective claims database analysis included adult patients with mild (GINA step 1) or severe asthma (GINA step 4). Maximum Treatment Step was measured within the first and second 90-day period after index date (the first date of asthma diagnosis during the inclusion period)...
July 4, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972094/seasonal-changes-influence-the-improvement-in-asthma-symptoms-by-exercise-training-in-subjects-with-asthma
#17
Felipe A R Mendes, Andrezza França-Pinto, Milton A Martins, Alberto Cukier, Rafael Stelmach, Pedro Giavina-Bianchi, Celso R F Carvalho
OBJECTIVE: To investigate whether patients with moderate to severe asthma who commence an exercise training program in winter or summer show differences in exercise capacity, health-related quality of life (HRQoL) and asthma symptoms. METHODS: Forty-two consecutive subjects visiting the outpatient clinic were enrolled in the 17-week rehabilitation program. One group of patients received the intervention from summer to winter (SWG, n = 21), and the other group participated from winter to summer (WSG, n = 21)...
July 4, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972089/effectiveness-of-fluticasone-furoate-vilanterol-versus-fluticasone-propionate-salmeterol-on-asthma-control-in-the-salford-lung-study
#18
Loretta Jacques, Nawar Diar Bakerly, John P New, Henrik Svedsater, James Lay-Flurrie, David A Leather
OBJECTIVE: The Asthma Salford Lung Study demonstrated the effectiveness of initiating once-daily fluticasone furoate/vilanterol (FF/VI) versus continuing usual care in asthma patients in UK primary care [1]. Here, we report a secondary analysis in a subset of patients with fluticasone propionate/salmeterol (FP/Salm) as their baseline intended maintenance therapy, to evaluate the relative effectiveness of initiating FF/VI versus continuing FP/Salm. METHODS: Adults with symptomatic asthma were randomised to initiate FF/VI 100[200]/25 µg or continue FP/Salm...
July 4, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972087/patient-preferences-for-a-touch-screen-tablet-based-asthma-questionnaire
#19
Samir Gupta, Victor Lam Shin Cheung, Monika Kastner, Sharon Straus, Alan Kaplan, Louis-Philippe Boulet, Joanna Em Sale
OBJECTIVE: Assessment of asthma control and provision of asthma action plans are seldom performed in practice, partly due to limited time for physicians to ascertain required information. A patient-facing electronic asthma questionnaire could facilitate information collection. We sought to design a touch-tablet asthma questionnaire for use in the clinic waiting room and to describe patient preferences for the content of such a questionnaire. METHODS: We created a questionnaire prototype based on best evidence and employed rapid-cycle design (semi-structured focus group testing; analysis; corresponding modifications; re-testing) with asthma patients aged ≥ 16 years...
July 4, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29972079/step-up-and-step-down-treatments-for-optimal-asthma-control-in-children-and-adolescents
#20
Jonathan A Bernstein, Lyndon Mansfield
OBJECTIVE: To review therapeutic options for stepwise management of pediatric asthma in the context of this population's unique needs such as potential effects of asthma, treatments, or both on growth and psychosocial development, and caregiver involvement. DATA SOURCES AND STUDY SELECTION: We conducted PubMed searches to identify relevant articles then reviewed resultant articles, guidelines for asthma management in children, and articles from personal files. RESULTS: Stepwise management of asthma, similar to adults, is recommended for children in current global and US guidelines...
July 4, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
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