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Journal of Acquired Immune Deficiency Syndromes: JAIDS

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https://www.readbyqxmd.com/read/27906768/understanding-local-context-is-necessary-for-hiv-and-hcv-prevention-planning
#1
Michelle M Van Handel, John T Brooks
No abstract text is available yet for this article.
November 30, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27906767/sleep-disturbance-among-hiv-infected-and-uninfected-veterans
#2
Julie A Womack, Terrence E Murphy, Harini Bathulapalli, Kathleen M Akgün, Cynthia Gibert, Ken M Kunisaki, David Rimland, Maria Rodriguez-Barradas, H Klar Yaggi, Amy C Justice, Nancy S Redeker
No abstract text is available yet for this article.
November 30, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27906766/prescription-of-post-exposure-prophylaxis-for-hiv-1-in-the-emergency-room-correct-transmission-risk-assessment-remains-challenging
#3
Alex Marzel, Henriette Heinrich, Lukas Schilliger, Jan S Fehr, Huldrych F Günthard, Roger Kouyos, Silvana K Rampini
BACKGROUND: Limited data are available about the accuracy of PEP prescription in the emergency rooms. Here, we evaluated PEP prescription decision-making with respect to the risk of sexual HIV transmission and the exposed person`s fear vis-à-vis HIV. METHODS: Using a risk-assessment algorithm, we retrospectively evaluated the adequacy of PEP prescription for all persons presenting at the emergency room of the University Hospital Zurich after consensual sex from 2007 to 2013...
November 30, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27898525/characterization-of-hcv-ns3-protease-variants-in-hcv-hiv-coinfected-patients-by-ultra-deep-sequence-analysis-relationship-to-hepatic-fibrosis
#4
Enass A Abdel-Hameed, Susan D Rouster, Xiang Zhang, Jing Chen, Mario Medvedovic, Zachary D Goodman, Kenneth E Sherman
BACKGROUND: Treatment of HCV/HIV coinfection is now largely based upon utilization of direct acting agents. Pre-treatment viral resistant-associated variants (RAVs) and host liver condition may affect the sustained virological response. In this study, we explored relative prevalence of protease resistance-associated mutations, the evolution of those RAVs following 12 weeks of pegylated interferon alfa exposure, and the role hepatic fibrosis might have on RAV display. METHODS: Thirty nonresponder HCV/ HIV coinfected subjects were evaluated pre- and post- 12 weeks of pegIFN treatment...
November 25, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27898526/uptake-of-hiv-pre-exposure-prophylaxis-prep-in-a-national-cohort-of-gay-and-bisexual-men-in-the-united-states-the-motivational-prep-cascade
#5
Jeffrey T Parsons, H Jonathon Rendina, Jonathan M Lassiter, Thomas H F Whitfield, Tyrel J Starks, Christian Grov
OBJECTIVES: The HIV care cascade provides milestones to track the progress of HIV-positive people from seroconversion through viral suppression. We propose a Motivational PrEP Cascade involving five stages based upon the Transtheoretical Model of Change. METHODS: We analyzed data from 995 men in One Thousand Strong, a longitudinal study of a national panel of HIV-negative gay and bisexual men in the United States. RESULTS: Nearly all (89%) participants were sexually active in the past 3 months, and 65% met CDC criteria for PrEP candidacy...
November 24, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27875363/pmtct-option-b-does-not-increase-preterm-birth-risk-and-may-prevent-extreme-prematurity-a-retrospective-cohort-study-in-malawi
#6
Maganizo B Chagomerana, William C Miller, Brian W Pence, Mina C Hosseinipour, Irving F Hoffman, Robert J Flick, Hannock Tweya, Soyapi Mumba, Frank Chibwandira, Kimberly A Powers
OBJECTIVE: To estimate preterm birth risk among infants of HIV-infected women in Lilongwe, Malawi according to maternal antiretroviral therapy (ART) status and initiation time under Option B+. DESIGN: Retrospective cohort study of HIV-infected women delivering at ≥27 weeks of gestation, April 2012-November 2015. Among women on ART at delivery, we restricted our analysis to those who initiated ART before 27 weeks of gestation. METHODS: We defined preterm birth as a singleton live birth at ≥27 and <37 weeks of gestation, with births at <32 weeks classified as extremely to very preterm...
November 21, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27875362/relationship-between-hiv-infection-antiretroviral-therapy-inflammatory-markers-and-cerebrovascular-endothelial-function-among-adults-in-urban-china
#7
Felicia C Chow, Yanling Li, Yinghuan Hu, Joy Chan, Huanling Wang, Weihai Xu, Richard W Price, Farzaneh A Sorond, Taisheng Li
BACKGROUND: Cerebrovascular risk is increased in people living with HIV infection compared with age-matched uninfected individuals. Cerebrovascular endothelial dysfunction related to antiretroviral therapy and inflammation may contribute to higher stroke risk in HIV infection. METHODS: We compared cerebral vasoreactivity-a measure of cerebrovascular endothelial function assessed by the breath holding index (BHI) using transcranial Doppler ultrasound-between virologically suppressed Chinese HIV-infected individuals followed in an HIV clinic in Beijing, China and uninfected controls...
November 21, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27875361/high-mobility-and-hiv-prevalence-among-female-market-traders-in-east-africa-in-2014
#8
Carol S Camlin, Alison M El Ayadi, Zachary A Kwena, Willi McFarland, Mallory O Johnson, Torsten B Neilands, Elizabeth A Bukusi, Craig R Cohen
BACKGROUND: The contribution of women's mobility to the HIV/AIDS epidemic in Africa is poorly understood, despite women's high mobility and evidence that it is associated with higher-risk sexual behavior. We sought to measure levels of mobility, HIV prevalence, and related risk behaviors among female traders in Kisumu, Kenya. METHODS: We used GPS mapping to develop a probability-based sample and recruited 305 female market traders for participation in a survey and voluntary HIV counseling and testing in 2014...
November 21, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27861243/differences-in-risk-behavior-and-demographic-factors-between-men-who-have-sex-with-men-with-acute-and-non-acute-human-immunodeficiency-virus-infection-in-a-community-based-testing-program-in-los-angeles
#9
Dvora Joseph Davey, Matthew Beymer, Chelsea P Roberts, Robert K Bolan, Jeffrey D Klausner
INTRODUCTION: High viremia combined with HIV-infection status unawareness and increased sexual risk behavior contributes to a disproportionate amount of new HIV infections. METHODS: From August 2011-July 2015, the Los Angeles LGBT Center conducted 66,546 HIV tests. We compared factors including the presence of concomitant sexually transmitted infections, number of recent sex partners and reported condomless anal intercourse between men who have sex with men (MSM) diagnosed with an acute HIV infection and a non-acute HIV infection using multivariable logistic regression...
November 15, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27861242/higher-cystatin-c-levels-are-associated-with-neurocognitive-impairment-in-older-hiv-adults
#10
Marissa E Sakoda, Pariya L Fazeli, Ronald J Ellis, Dilip V Jeste, Igor Grant, Scott L Letendre, David J Moore
OBJECTIVE: The study aims to determine whether cystatin C is associated with HIV disease and HIV-associated neurocognitive impairment (NCI). METHODS: Participants included 124 (HIV+ n = 77; HIV- n = 47) older adults (age ≥ 50 years) examined at the UCSD HIV Neurobehavioral Research Program. Cystatin C, a biomarker of kidney functioning that has been linked to poor health outcomes, was measured in blood. Participants completed a comprehensive neurocognitive assessment that was used to define both global and domain NCI...
November 15, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27861235/prolonged-viral-suppression-over-a-12-year-follow-up-of-hiv-infected-patients-the-persistent-impact-of-adherence-at-4-months-after-initiation-of-combined-antiretroviral-therapy-in-the-anrs-co8-aproco-copilote-cohort
#11
Camelia Protopopescu, Maria Patrizia Carrieri, François Raffi, Odile Picard, Lucile Hardel, Lionel Piroth, Corinne Jadand, Janine Pierret, Bruno Spire, Catherine Leport
The effect of early adherence on long-term viral suppression was assessed among 1,281 HIV-patients starting a protease inhibitor-containing regimen in 1997-1999, followed up to 12 years. Association between 4-months adherence (three-level score) and prolonged viral suppression (PVS) was evaluated using a multivariate mixed logistic model in 891 eligible patients. High 4-months adherence (OR [95% CI]: 3.72 [1.98 to 6.98]) was associated with long-term PVS, irrespective of maintenance adherence. This unexpected long-term virological impact of early adherence reinforces the message that, when starting antiretrovirals, all means should be mobilized to ensure optimum early adherence to achieve prolonged antiretroviral success...
November 15, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27861234/violence-from-a-sexual-partner-is-significantly-associated-with-poor-hiv-care-and-treatment-outcomes-among-female-sex-workers-in-the-dominican-republic
#12
Carlisdania Mendoza, Clare Barrington, Yeycy Donastorg, Martha Perez, Paul Fleming, Michele Decker, Deanna Kerrigan
BACKGROUND: Female sex workers (FSW) experience high rates of violence from their sexual partners. While violence is associated with HIV risk behaviors among FSW, there is limited evidence on the association between violence and HIV treatment outcomes. METHODS: We analyzed data from a socio-behavioral survey with a cohort of FSW living with HIV in the Dominican Republic (n=268) to describe the burden of violence from a sexual partner in the last 6 months. We assessed the relationship between violence and HIV treatment outcomes, comparing findings across two types of sexual partners: intimate partners and clients...
November 15, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27861241/lost-opportunities-concerning-loss-to-follow-up-a-response-to-elul-et-al
#13
Paula D Strassle, Jacqueline E Rudolph, Bryna J Harrington, Sara N Levintow
No abstract text is available yet for this article.
November 14, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27861240/semen-bacterial-concentrations-and-hiv-1-rna-shedding-among-hiv-1-seropositive-kenyan-men
#14
Christine Korhonen, Sujatha Srinivasan, Dandi Huang, Daisy L Ko, Eduard J Sanders, Norbert M Peshu, John N Krieger, Charles H Muller, Robert W Coombs, David N Fredricks, Susan M Graham
INTRODUCTION: HIV-1 is transmitted through semen from men to their sexual partners. Genital infections can increase HIV-1 RNA shedding in semen, but shedding also occurs in the absence of typical pathogens. We hypothesized that higher bacterial concentrations in semen would be associated with higher HIV-1 RNA levels. METHODS: We analyzed semen samples from 42 HIV-1 seropositive Kenyan men using quantitative PCR to assess bacterial concentrations and real-time PCR to measure HIV-1 RNA levels...
November 14, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27861239/increased-survival-among-hiv-infected-pwid-receiving-a-multi-level-hiv-risk-and-stigma-reduction-intervention-results-from-a-randomized-controlled-trial
#15
Vivian F Go, Constantine Frangakis, Nguyen Le Minh, Tran Viet Ha, Carl A Latkin, Teerada Sripaipan, Carla E Zelaya, Wendy W Davis, David D Celentano, Vu Minh Quan
OBJECTIVE: In Vietnam, where 58% of prevalent HIV cases are attributed to PWID, we evaluated whether a multi-level intervention could improve care outcomes and increase survival. METHODS: We enrolled 455 HIV-infected male PWID from 32 communes in Thai Nguyen Province. Communes were randomized to a community stigma reduction intervention or standard of care and then within each commune, to an individual enhanced counseling intervention or standard of care, resulting in four arms: Arm 1 (standard of care); Arm 2 (community intervention alone); Arm 3 (individual intervention alone); and Arm 4 (community + individual interventions)...
November 14, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27861238/complementary-feeding-and-diarrhea-and-respiratory-infection-among-hiv-exposed-tanzanian-infants
#16
P Kamenju, E Liu, E Hertzmark, D Spiegelman, R R Kisenge, R Kupka, S Aboud, K P Manji, C Duggan, W W Fawzi
OBJECTIVE: To examine the association between complementary feeding (CF) and risks of diarrhea and acute respiratory infection (ARI) among HIV-exposed infants aged 6-24 months. DESIGN: We prospectively employed an Infant and Child Feeding Index (ICFI) to measure CF practices (breastfeeding status, food consistency, dietary diversity, food group frequency and meal frequency). We determined the association of ICFI and each of its components with the risk of diarrhea and ARI...
November 14, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27861237/psychosocial-predictors-of-engagement-in-sexual-risk-behavior-among-trans-female-youth-ages-16-24-years-in-san-francisco
#17
Caitlin M Turner, Glenn-Milo Santos, Sean Arayasirikul, Erin C Wilson
BACKGROUND: Trans*female youth (TFY) carry a disproportionate burden of HIV. Few longitudinal studies have analyzed both proximal and upstream predictors of changes in HIV-related risk behaviors for TFY. The present analysis aims to identify psychosocial predictors of changes in sexual risk behavior over time for TFY in the San Francisco Bay area. METHODS: Data come from the SHINE cohort study conducted at the San Francisco Department of Public Health from 2012-2014 (n=263)...
November 14, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27861236/healthcare-access-and-prep-continuation-in-san-francisco-and-miami-following-the-u-s-prep-demo-project
#18
Susanne Doblecki-Lewis, Albert Liu, Daniel Feaster, Stephanie E Cohen, Gabriel Cardenas, Oliver Bacon, Erin Andrew, Michael A Kolber
Pre-exposure prophylaxis (PrEP) for prevention of HIV infection has demonstrated efficacy in randomized controlled trials as well as in demonstration projects. For PrEP implementation to result in significant reductions in HIV incidence for men who have sex with men (MSM) in the United States, sufficient access to PrEP care and continued engagement outside of demonstration projects is required. We report the results of a follow-up survey of 173 former participants from the Miami and San Francisco sites of the U...
November 14, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27846036/virological-blips-and-predictors-of-post-treatment-viral-control-after-stopping-art-started-in-primary-hiv-infection
#19
Sarah Fidler, Ashley D Olson, Heiner C Bucher, Julie Fox, John Thornhill, Charles Morrison, Roberto Muga, Andrew Phillips, John Frater, Kholoud Porter
BACKGROUND: Few individuals commencing antiretroviral therapy (ART) in primary HIV infection (PHI) maintain undetectable viraemia following treatment cessation. Associated factors remain unclear given the importance of the phenomenon to cure research. METHODS: Using CASCADE data of seroconverters starting ART in PHI (≤6 months from seroconversion), we estimated proportions experiencing viral blips (>400 copies followed by <400 copies HIV RNA/mL without alteration of regimen) while on ART...
November 8, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27828879/in-response-to-gueudin-et-al-xpert%C3%A2-hiv-1-viral-load-assay-and-versant%C3%A2-hiv-1-rna-1-5-assay-a-performance-comparison
#20
B Bruzzone, P Caligiuri, N Nigro, C Arcuri, S Delucis, A Di Biagio, G Icardi
No abstract text is available yet for this article.
November 5, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
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