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Investigative Radiology

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https://www.readbyqxmd.com/read/28492418/clinical-feasibility-of-free-breathing-dynamic-t1-weighted-imaging-with-gadoxetic-acid-enhanced-liver-magnetic-resonance-imaging-using-a-combination-of-variable-density-sampling-and-compressed-sensing
#1
Jeong Hee Yoon, Mi Hye Yu, Won Chang, Jin-Young Park, Marcel Dominik Nickel, Yohan Son, Berthold Kiefer, Jeong Min Lee
OBJECTIVES: The purpose of the study was to investigate the clinical feasibility of free-breathing dynamic T1-weighted imaging (T1WI) using Cartesian sampling, compressed sensing, and iterative reconstruction in gadoxetic acid-enhanced liver magnetic resonance imaging (MRI). MATERIALS AND METHODS: This retrospective study was approved by our institutional review board, and the requirement for informed consent was waived. A total of 51 patients at high risk of breath-holding failure underwent dynamic T1WI in a free-breathing manner using volumetric interpolated breath-hold (BH) examination with compressed sensing reconstruction (CS-VIBE) and hard gating...
May 11, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28463932/compressed-sensing-for-breast-mri-resolving-the-trade-off-between-spatial-and-temporal-resolution
#2
Suzan Vreemann, Alejandro Rodriguez-Ruiz, Dominik Nickel, Laura Heacock, Linda Appelman, Jan van Zelst, Nico Karssemeijer, Elisabeth Weiland, Marnix Maas, Linda Moy, Berthold Kiefer, Ritse M Mann
OBJECTIVE: Ultrafast dynamic contrast-enhanced magnetic resonance imaging of the breast enables assessment of the contrast inflow dynamics while providing images with diagnostic spatial resolution. However, the slice thickness of common ultrafast techniques still prevents multiplanar reconstruction. In addition, some temporal blurring of the enhancement characteristics occurs in case view-sharing is used. We evaluate a prototype compressed-sensing volume-interpolated breath-hold examination (CS-VIBE) sequence for ultrafast breast MRI that improves through plane spatial resolution and avoids temporal blurring while maintaining an ultrafast temporal resolution (less than 5 seconds per volume)...
May 1, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28463931/multiparametric-magnetic-resonance-imaging-of-the-prostate-repeatability-of-volume-and-apparent-diffusion-coefficient-quantification
#3
Andriy Fedorov, Mark G Vangel, Clare M Tempany, Fiona M Fennessy
OBJECTIVES: The aim of this study was to evaluate the repeatability of a region of interest (ROI) volume and mean apparent diffusion coefficient (ADC) in standard-of-care 3 T multiparametric magnetic resonance imaging (mpMRI) of the prostate obtained with the use of endorectal coil. MATERIALS AND METHODS: This prospective study was Health Insurance Portability and Accountability Act compliant, with institutional review board approval and written informed consent...
May 1, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28459800/t2-weighted-4d-magnetic-resonance-imaging-for-application-in-magnetic-resonance-guided-radiotherapy-treatment-planning
#4
Joshua N Freedman, David J Collins, Hannah Bainbridge, Christopher M Rank, Simeon Nill, Marc Kachelrieß, Uwe Oelfke, Martin O Leach, Andreas Wetscherek
OBJECTIVES: The aim of this study was to develop and verify a method to obtain good temporal resolution T2-weighted 4-dimensional (4D-T2w) magnetic resonance imaging (MRI) by using motion information from T1-weighted 4D (4D-T1w) MRI, to support treatment planning in MR-guided radiotherapy. MATERIALS AND METHODS: Ten patients with primary non-small cell lung cancer were scanned at 1.5 T axially with a volumetric T2-weighted turbo spin echo sequence gated to exhalation and a volumetric T1-weighted stack-of-stars spoiled gradient echo sequence with golden angle spacing acquired in free breathing...
April 28, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28459799/mapping-an-extended-neurochemical-profile-at-3-and-7-t-using-accelerated-high-resolution-proton-magnetic-resonance-spectroscopic-imaging
#5
Stephan Gruber, Eva Heckova, Bernhard Strasser, Michal Považan, Gilbert J Hangel, Lenka Minarikova, Siegfried Trattnig, Wolfgang Bogner
OBJECTIVES: The aim of this study was to compare high-resolution free induction decay magnetic resonance spectroscopic imaging (FID-MRSI) at 3 T and 7 T in the brain of healthy subjects and to showcase the clinical potential of accelerated FID-MRSI at 7 T in 2 brain tumor cases. MATERIALS AND METHODS: In this institutional review board-approved study, 10 healthy volunteers (8 men/2 women; age: 31 ± 6 years) were measured at 3 T and 7 T (Trio and 7T-Magnetom; Siemens Healthcare, Germany) and 2 patients (a 38-year-old man and a 37-year-old man), 1 with an anaplastic oligoastrocytoma (grade III) and 1 with a low-grade glioma (oligodendroglioma), were measured at 7 T...
April 28, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28448310/comparison-of-power-versus-manual-injection-in-bolus-shape-and-image-quality-on-contrast-enhanced-magnetic-resonance-angiography-an-experimental-study-in-a-swine-model
#6
Takahiro Tsuboyama, Gregor Jost, Hubertus Pietsch, Noriyuki Tomiyama
OBJECTIVE: The aim of this study was to compare power versus manual injection in bolus shape and image quality on contrast-enhanced magnetic resonance angiography (CE-MRA). MATERIALS AND METHODS: Three types of CE-MRA (head-neck 3-dimensional [3D] MRA with a test-bolus technique, thoracic-abdominal 3D MRA with a bolus-tracking technique, and thoracic-abdominal time-resolved 4-dimensional [4D] MRA) were performed after power and manual injection of gadobutrol (0...
April 26, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28448309/clinical-feasibility-of-3-dimensional-magnetic-resonance-cholangiopancreatography-using-compressed-sensing-comparison-of-image-quality-and-diagnostic-performance
#7
Jeong Hee Yoon, Sang Min Lee, Hyo-Jin Kang, Elisabeth Weiland, Esther Raithel, Yohan Son, Berthold Kiefer, Jeong Min Lee
OBJECTIVE: The aim of this study was to evaluate the clinical feasibility of fast 3-dimensional (3D) magnetic resonance cholangiopancreatography (MRCP) using compressed sensing (CS) in comparison with conventional navigator-triggered 3D-MRCP. MATERIALS AND METHODS: This retrospective study was approved by our institutional review board, and the requirement of informed consent was waived. A total of 84 patients (male-to-female ratio, 41:43; mean age, 47.3 ± 18.8 years) who underwent conventional 3D navigator-triggered T2-weighted MRCP using sampling perfection with application optimized contrasts (SPACE) and fast 3D MRCP using SPACE with high undersampling combined with CS reconstruction (CS SPACE; CS-MRCP) on a 3 T scanner were included...
April 26, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28441159/application-of-high-speed-t1-sequences-for-high-quality-hepatic-arterial-phase-magnetic-resonance-imaging-intraindividual-comparison-of-single-and-multiple-arterial-phases
#8
Yang Shin Park, Chang Hee Lee, Jeong Woo Kim, Young-Sun Lee, MunYoung Paek, Kyeong Ah Kim
PURPOSE: The aim of this study was to compare intraindividual single and multiple arterial phase acquisitions and evaluate which acquisition method was more advantageous for obtaining high-quality hepatic arterial phase in gadoxetic acid-enhanced liver magnetic resonance imaging (MRI). MATERIALS AND METHODS: Sixty-seven patients who underwent gadoxetic acid-enhanced liver MRIs and had all 3 kinds of acquisitions (single, dual, and triple arterial phases) were retrospectively included...
April 24, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28430716/simultaneous-multislice-accelerated-turbo-spin-echo-magnetic-resonance-imaging-comparison-and-combination-with-in-plane-parallel-imaging-acceleration-for-high-resolution-magnetic-resonance-imaging-of-the-knee
#9
Jan Fritz, Benjamin Fritz, Jialu Zhang, Gaurav K Thawait, Dharmdev H Joshi, Li Pan, Dingxin Wang
PURPOSE: We prospectively quantified the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of integrated parallel acquisition technique (PAT) and simultaneous multislice (SMS) acceleration and various combinations thereof, and we further compared two 4-fold-accelerated (PAT2-SMS2) high-resolution turbo spin echo (TSE) magnetic resonance imaging (MRI) protocols of the knee against a clinical 2-fold-accelerated (PAT2-SMS1) TSE standard. MATERIALS AND METHODS: Institutional review board approval was obtained, and all subjects gave informed consent...
April 20, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28430715/computed-tomography-of-the-head-and-neck-region-for-tumor-staging-comparison-of-dual-source-dual-energy-and-low-kilovolt-single-energy-acquisitions
#10
Matthias Stefan May, Joscha Bruegel, Michael Brand, Marco Wiesmueller, Bernhard Krauss, Thomas Allmendinger, Michael Uder, Wolfgang Wuest
PURPOSE: The aim of this study was to intra-individually compare the image quality obtained by dual-source, dual-energy (DSDE) computed tomography (CT) examinations and different virtual monoenergetic reconstructions to a low single-energy (SE) scan. MATERIALS AND METHODS: Third-generation DSDE-CT was performed in 49 patients with histologically proven malignant disease of the head and neck region. Weighted average images (WAIs) and virtual monoenergetic images (VMIs) for low (40 and 60 keV) and high (120 and 190 keV) energies were reconstructed...
April 20, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28430714/ultrasound-molecular-imaging-of-inflammation-in-mouse-abdominal-aorta
#11
Shiying Wang, Sunil Unnikrishnan, Elizabeth B Herbst, Alexander L Klibanov, Frank William Mauldin, John A Hossack
OBJECTIVES: The aim of this study was to demonstrate a new clinically translatable ultrasound molecular imaging approach, modulated acoustic radiation force-based imaging, which is capable of rapid and reliable detection of inflammation as validated in mouse abdominal aorta. MATERIALS AND METHODS: Animal studies were approved by the Institutional Animal Care and Use Committee at the University of Virginia. C57BL/6 mice stimulated with tumor necrosis factor α, or fed with a high-fat diet, were used as inflammation (MInflammation) and diet-induced obesity (DIO) (MDIO) models, respectively...
April 20, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28422807/clinical-robustness-of-accelerated-and-optimized-abdominal-diffusion-weighted-imaging
#12
Jana Taron, Jakob Weiß, Petros Martirosian, Ferdinand Seith, Alto Stemmer, Fabian Bamberg, Mike Notohamiprodjo
OBJECTIVES: The aim of this study was to assess the robustness of an accelerated and optimized diffusion-weighted sequence in clinical routine abdominal imaging using the simultaneous multislice (SMS) technique for scan time reduction and 3-dimensional (3D) diagonal diffusion mode to optimize image quality. MATERIALS AND METHODS: One hundred fifty consecutive patients received clinically indicated magnetic resonance imaging for abdominal imaging including an optimized SMS diffusion-weighted sequence (DWIOPT: diffusion mode 3D diagonal; SMS factor 2; scan time 1:44 minutes)...
April 19, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28422806/improvement-of-image-quality-in-unenhanced-dual-layer-ct-of-the-head-using-virtual-monoenergetic-images-compared-with-polyenergetic-single-energy-ct
#13
Victor Neuhaus, Nuran Abdullayev, Nils Große Hokamp, Gregor Pahn, Christoph Kabbasch, Anastasios Mpotsaris, David Maintz, Jan Borggrefe
OBJECTIVES: The aims of this study were to compare virtual monoenergetic images and polyenergetic images reconstructed from unenhanced dual-layer detector computed tomography (DLCT) of the head and to determine kiloelectron volt levels that optimize image quality, particularly the gray-white matter contrast, and reduce beam hardening artifacts caused by the skull. MATERIALS AND METHODS: Institutional review board approval was obtained. Forty patients that received DLCT were included in this retrospective study; of these patients, 22 were women and 18 were men...
April 19, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28398929/comprehensive-dynamic-contrast-enhanced-3d-magnetic-resonance-imaging-of-the-breast-with-fat-water-separation-and-high-spatiotemporal-resolution-using-radial-sampling-compressed-sensing-and-parallel-imaging
#14
Thomas Benkert, Kai Tobias Block, Samantha Heller, Melanie Moccaldi, Daniel K Sodickson, Sungheon Gene Kim, Linda Moy
OBJECTIVES: The aim of this study was to assess the applicability of Dixon radial volumetric encoding (Dixon-RAVE) for comprehensive dynamic contrast-enhanced 3D magnetic resonance imaging (MRI) of the breast using a combination of radial sampling, model-based fat/water separation, compressed sensing, and parallel imaging. MATERIALS AND METHODS: In this Health Insurance Portability and Accountability Act-compliant prospective study, 24 consecutive patients underwent bilateral breast MRI, including both conventional fat-suppressed and non-fat-suppressed precontrast T1-weighted volumetric interpolated breath-hold examination (VIBE)...
April 11, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28383307/the-thrombolytic-effect-of-diagnostic-ultrasound-induced-microbubble-cavitation-in-acute-carotid-thromboembolism
#15
Thomas R Porter, Feng Xie, John Lof, Jeffry Powers, Francois Vignon, William Shi, Matthew White
BACKGROUND: Acute ischemic stroke is often due to thromboembolism forming over ruptured atherosclerotic plaque in the carotid artery (CA). The presence of intraluminal CA thrombus is associated with a high risk of thromboembolic cerebral ischemic events. The cavitation induced by diagnostic ultrasound high mechanical index (MI) impulses applied locally during a commercially available intravenous microbubble infusion has dissolved intravascular thrombi, especially when using longer pulse durations...
April 5, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28379863/improved-magnetic-resonance-imaging-pathology-correlation-with-imaging-derived-3d-printed-patient-specific-whole-mount-molds-of-the-prostate
#16
Daniel N Costa, Yonatan Chatzinoff, Niccolo M Passoni, Payal Kapur, Claus G Roehrborn, Yin Xi, Neil M Rofsky, Jose Torrealba, Franto Francis, Cecil Futch, Phyllis Hagens, Hollis Notgrass, Susana Otero-Muinelo, Ivan Pedrosa, Rajiv Chopra
OBJECTIVES: The aim of this study was to compare the anatomical registration of preoperative magnetic resonance imaging (MRI) and prostate whole-mount obtained with 3D-printed, patient-specific, MRI-derived molds (PSM) versus conventional whole-mount sectioning (WMS). MATERIALS AND METHODS: Based on an a priori power analysis, this institutional review board-approved study prospectively included 50 consecutive men who underwent 3 T multiparametric prostate MRI followed by radical prostatectomy...
April 4, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28368879/bowel-angioedema-associated-with-iodinated-contrast-media-incidence-and-predisposing-factors
#17
Nieun Seo, Yong Eun Chung, Joon Seok Lim, Mi Kyung Song, Myeong-Jin Kim, Ki Whang Kim
OBJECTIVE: Bowel angioedema is an acute adverse reaction to iodinated contrast media (CM) that involves the gastrointestinal tract. We aimed to investigate the incidence and predisposing factors of iodinated CM-associated bowel angioedema during computed tomography (CT) examinations. MATERIALS AND METHODS: This study was approved by our institutional review board, and informed consent was waived due to its retrospective design. From July 2013 to July 2015, adult patients with a history of adverse reactions to iodinated CM during CT (group A, n = 427) and patients without adverse reactions matched for age and sex with the propensity-score matching method (group B, n = 427) were studied...
April 1, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28306699/dynamic-measurement-of-arterial-liver-perfusion-with-an-interventional-c-arm-system
#18
Sanjit Datta, Kerstin Müller, Terilyn Moore, Lior Molvin, Sonja Gehrisch, Jarrett Rosenberg, Yamil Saenz, Michael Manhart, Yu Deuerling-Zheng, Nishita Kothary, Rebecca Fahrig
PURPOSE: Objective intraprocedural measurement of hepatic blood flow could provide a quantitative treatment end point for locoregional liver procedures. This study aims to validate the accuracy and reproducibility of cone-beam computed tomography perfusion (CBCTp) measurements of arterial liver perfusion (ALP) against clinically available computed tomography perfusion (CTp) measurements in a swine embolization model. METHODS: Triplicate CBCTp measurements using a selective arterial contrast injection were performed before and after complete embolization of the left lobe of the liver in 5 swine...
March 17, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28291025/evaluation-of-reproducibility-of-diffusion-tensor-imaging-in-the-brachial-plexus-at-3-0-t
#19
Michael J Ho, Andrei Manoliu, Felix Pierre Kuhn, Bram Stieltjes, Markus Klarhöfer, Thorsten Feiweier, Magda Marcon, Gustav Andreisek
OBJECTIVE: The aim of this study was to evaluate the reproducibility of 3 T magnetic resonance imaging diffusion tensor imaging (DTI) of the brachial plexus in healthy subjects. METHODS: Ten healthy volunteers were included, and morphological and DTI sequences of the nerve roots of the brachial plexus from C5 to T1 of both sides were repeatedly acquired on a 3 T magnetic resonance system (MAGNETOM Skyra; Siemens Healthcare, Erlangen, Germany). A prototype diffusion-weighted single-shot echo-planar imaging sequence-enabling slice-specific shim adjustments was performed with b-values of 0 and 800 s/mm in 30 gradient directions, resulting in an acquisition time of about 6 minutes each in axial orientation...
March 13, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28257339/symri-of-the-brain-rapid-quantification-of-relaxation-rates-and-proton-density-with-synthetic-mri-automatic-brain-segmentation-and-myelin-measurement
#20
Akifumi Hagiwara, Marcel Warntjes, Masaaki Hori, Christina Andica, Misaki Nakazawa, Kanako Kunishima Kumamaru, Osamu Abe, Shigeki Aoki
Conventional magnetic resonance images are usually evaluated using the image signal contrast between tissues and not based on their absolute signal intensities. Quantification of tissue parameters, such as relaxation rates and proton density, would provide an absolute scale; however, these methods have mainly been performed in a research setting. The development of rapid quantification, with scan times in the order of 6 minutes for full head coverage, has provided the prerequisites for clinical use. The aim of this review article was to introduce a specific quantification method and synthesis of contrast-weighted images based on the acquired absolute values, and to present automatic segmentation of brain tissues and measurement of myelin based on the quantitative values, along with application of these techniques to various brain diseases...
March 3, 2017: Investigative Radiology
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