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Human Reproduction

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https://www.readbyqxmd.com/read/28073974/infertile-women-who-screen-positive-for-depression-are-less-likely-to-initiate-fertility-treatments
#1
Natalie M Crawford, Heather S Hoff, Jennifer E Mersereau
STUDY QUESTION: Are infertile women who screen positive for depression less likely to initiate infertility treatments? SUMMARY ANSWER: Infertile women who screen positive for depression are less likely to initiate treatment for infertility. WHAT IS ALREADY KNOWN: Infertility imposes a psychological burden on many couples. Depression and anxiety have been demonstrated in ~40% of infertile women, which is twice that of fertile women. Further, the psychological burden associated with infertility treatment has been cited as a major factor for discontinuation of infertility care...
January 9, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28073973/human-foetal-ovary-shares-meiotic-preventing-factors-with-the-developing-testis
#2
Nelly Frydman, Marine Poulain, Brahim Arkoun, Clotilde Duquenne, Sophie Tourpin, Sébastien Messiaen, René Habert, Virginie Rouiller-Fabre, Alexandra Benachi, Gabriel Livera
STUDY QUESTION: How can pre-meiotic germ cells persist in the human foetal ovary? SUMMARY ANSWER: Numerous oogonia escaping meiotic entry were retrieved throughout human ovarian development simultaneously with the expression of signalling pathways preventing meiosis, typically described in the rodent embryonic testis. WHAT IS KNOWN ALREADY: The transition from mitosis to meiosis is a key event in female germ cells that remains poorly documented in research on the human ovary...
January 9, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28073972/awareness-and-attitude-regarding-reproductive-options-of-persons-carrying-a-brca-mutation-and-their-partners
#3
J J G Gietel-Habets, C E M de Die-Smulders, I A P Derks-Smeets, A Tibben, V C G Tjan-Heijnen, R van Golde, E Gomez-Garcia, C M Kets, L A D M van Osch
STUDY QUESTION: To what extent are BRCA mutation carriers and their partners in the Netherlands aware about preimplantation genetic diagnosis (PGD) and prenatal diagnosis (PND) as reproductive options and what is their attitude towards these options? SUMMARY ANSWER: Awareness of PGD (66%) and PND (61%) among BRCA mutation carriers and their partners is relatively high and 80% and 26%, respectively, of BRCA carriers and their partners find offering PGD and PND for hereditary breast and ovarian cancer (HBOC) acceptable...
January 9, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28069732/weight-management-practices-associated-with-pcos-and-their-relationships-with-diet-and-physical-activity
#4
L J Moran, W J Brown, S A McNaughton, A E Joham, H J Teede
STUDY QUESTION: Do weight management practices differ in women with and without PCOS? SUMMARY ANSWER: Women in the general population with self-reported PCOS are more likely to be using healthy weight management practices and alternative non-lifestyle measures for weight management than women without PCOS. WHAT IS KNOWN ALREADY: Lifestyle management is the first-line treatment in PCOS. However, the specific weight management practices used by women with PCOS and their effect on diet and physical activity are unclear...
January 8, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28077604/the-mitochondrial-dna-content-of-cumulus-granulosa-cells-is-linked-to-embryo-quality
#5
V Desquiret-Dumas, A Clément, V Seegers, L Boucret, V Ferré-L'Hotellier, P E Bouet, P Descamps, V Procaccio, P Reynier, P May-Panloup
STUDY QUESTION: Could the mitochondrial DNA (mtDNA) content of cumulus granulosa cells (CGCs) be related to oocyte competence? SUMMARY ANSWER: The quality of embryos obtained during IVF procedures appears to be linked to mtDNA copy numbers in the CGCs. WHAT IS KNOWN ALREADY: Oocyte quality is linked to oocyte mtDNA content in the human and other species, and the mtDNA copy number of the oocyte is related to that of the corresponding CGCs. Moreover, the quantification of CGC mtDNA has recently been proposed as a biomarker of embryo viability...
January 6, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28077439/the-functional-expression-of-transient-receptor-potential-channels-in-the-mouse-endometrium
#6
Katrien De Clercq, Charlotte Van den Eynde, Aurélie Hennes, Rieta Van Bree, Thomas Voets, Joris Vriens
STUDY QUESTION: Does mouse endometrial epithelial cells and stromal cells have a similar transient receptor potential (TRP)-channel expression profile and to that found in the human endometrium? SUMMARY ANSWER: Mouse endometrial epithelial and stromal cells have a distinct TRP channel expression profile analogous to what has been found in human endometrium, and hence suggests the mouse a good model to investigate the role of TRP channels in reproduction. WHAT IS KNOWN ALREADY: An optimal intercellular communication between epithelial and stromal endometrial cells is crucial for successful reproduction...
January 6, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28077428/reproductive-experiences-of-women-who-cryopreserved-oocytes-for-non-medical-reasons
#7
Karin Hammarberg, Maggie Kirkman, Natasha Pritchard, Martha Hickey, Michelle Peate, John McBain, Franca Agresta, Chris Bayly, Jane Fisher
STUDY QUESTION: What are the reproductive experiences of women who cryopreserve oocytes for non-medical reasons? SUMMARY ANSWER: One in three women had been pregnant at some stage in their lives and while most still wanted to have a child or another child, very few had used their stored oocytes, predominantly because they did not want to be single parents. WHAT IS KNOWN ALREADY: The number of healthy women who freeze oocytes to avoid age-related infertility is increasing...
January 6, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28057878/pseudoautosomal-abnormalities-in-terminal-azfb-c-deletions-are-associated-with-isochromosomes-yp-and-may-lead-to-abnormal-growth-and-neuropsychiatric-function
#8
A Castro, F Rodríguez, M Flórez, P López, B Curotto, D Martínez, A Maturana, M C Lardone, C Palma, V Mericq, M Ebensperger, F Cassorla
STUDY QUESTION: Are copy number variations (CNVs) in the pseudoautosomal regions (PARs) frequent in subjects with Y-chromosome microdeletions and can they lead to abnormal stature and/or neuropsychiatric disorders? SUMMARY ANSWER: Only subjects diagnosed with azoospermia factor (AZF)b+c deletions spanning to the end of the Y chromosome (i.e. terminal deletions) harbor Y isochromosomes and/or cells 45,X that lead to pseudoautosomal gene CNVs, which were associated with abnormal stature and/or neuropsychiatric disorders...
January 5, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28057877/previous-miscarriages-and-gli2-are-associated-with-anorectal-malformations-in-offspring
#9
Romy van de Putte, Charlotte H W Wijers, Ivo de Blaauw, Carlo L M Marcelis, Cornelius E J Sloots, Alice S Brooks, Paul M A Broens, Nel Roeleveld, Loes F M van der Zanden, Iris A L M van Rooij
STUDY QUESTION: Are anorectal malformations (ARMs) associated with previous miscarriages or single nucleotide polymorphisms (SNPs) in the Bone Morphogenetic Protein 4 (BMP4) and GLI family zinc finger 2 (GLI2) genes? SUMMARY ANSWER: The SNP rs3738880 in GLI2 and miscarriages were associated with ARM, especially in patients with multiple congenital anomalies (MCA). WHAT IS KNOWN ALREADY: ARM are one of the most common birth defects of the gastrointestinal tract...
January 5, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28057876/academic-performance-in-adolescents-born-after-art-a-nationwide-registry-based-cohort-study
#10
A L Spangmose, S S Malchau, L Schmidt, D Vassard, S Rasmussen, A Loft, J Forman, A Pinborg
STUDY QUESTION: Is academic performance in adolescents aged 15-16 years and conceived after ART, measured as test scores in ninth grade, comparable to that for spontaneously conceived (SC) adolescents? SUMMARY ANSWER: ART singletons had a significantly lower mean test score in the adjusted analysis when compared with SC singletons, yet the differences were small and probably not of clinical relevance. WHAT IS KNOWN ALREADY: Previous studies have shown similar intelligence quotient (IQ) levels in ART and SC children, but only a few have been on adolescents...
January 5, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28057875/perceived-challenges-of-working-in-a-fertility-clinic-a-qualitative-analysis-of-work-stressors-and-difficulties-working-with-patients
#11
Jacky Boivin, Laura Bunting, Emily Koert, Chin Ieng U, Christianne Verhaak
STUDY QUESTION: What are some of the challenges of working in a fertility clinic? SUMMARY ANSWER: The most frequently mentioned challenges were workload (e.g. high time pressure) and patient-related sources (e.g. unrealistic expectations). WHAT IS KNOWN ALREADY: One study showed a too high workload, worry about handling human material and low success rates were main stressors in fertility clinics. STUDY DESIGN, SIZE, DURATION: An online open-ended survey inviting participants to respond to seven questions was distributed to 5902 members of the European Society for Human Reproduction and Embryology (ESHRE, October 2010)...
January 5, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28057874/pregnancy-and-live-birth-rates-after-microsurgical-vasoepididymostomy-for-azoospermic-patients-with-epididymal-obstruction
#12
Jing Peng, Zhichao Zhang, Yiming Yuan, Wanshou Cui, Weidong Song
STUDY QUESTION: Can microsurgical vasoepididymostomy (MVE) be an effective treatment for azoospermic men with epididymal obstruction? SUMMARY ANSWER: MVE is an effective treatment for epididymal obstruction, with overall patency and live birth rates of 76.3% and 34.8%, respectively. WHAT IS KNOWN ALREADY: We showed that MVE was an effective treatment for non-vasectomized patients with epididymal obstruction and prior failed sperm retrieval for ICSI...
January 5, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28043946/reply-detecting-mosaicism-in-trophectoderm-biopsies
#13
LETTER
Antonio Capalbo, Filippo Ubaldi, Laura Rienzi, Richard Scott, Nathan Treff
No abstract text is available yet for this article.
January 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28043945/detecting-mosaicism-in-trophectoderm-biopsies
#14
LETTER
Karen D Sermon, Claudia Spits, Afroditi Mertzanidou, Joris R Vermeesch, Francesco Fiorentino
No abstract text is available yet for this article.
January 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28043944/should-we-also-work-on-an-international-informed-consent-for-endometriosis-surgery
#15
LETTER
David Soriano, Bouaziz Jerome
No abstract text is available yet for this article.
January 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28043943/reply-should-we-also-work-on-an-international-informed-consent-for-endometriosis-surgery
#16
LETTER
A Vanhie, C Meuleman, C Tomassetti, D Timmerman, A D'Hoore, A Wolthuis, B Van Cleynenbreugel, E Dancet, U Van den Broeck, J Tsaltas, S P Renner, A D Ebert, F Carmona, J Abbott, A Stepniewska, H Taylor, E Saridogan, M Mueller, J Keckstein, N Pluchino, E Zupi, G Dunselman, M S Abrao, C Chapron, T D'Hooghe
No abstract text is available yet for this article.
January 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28039228/all-aspects-of-human-art-must-be-considered-not-just-the-embryo-culture-medium
#17
LETTER
Donald Rieger
No abstract text is available yet for this article.
December 29, 2016: Human Reproduction
https://www.readbyqxmd.com/read/28039227/reply-ii-embryo-culture-media-effects
#18
LETTER
Sander H M Kleijkers, Eleni Mantikou, Els Slappendel, Dimitri Consten, Jannie van Echten-Arends, Alex M Wetzels, Madelon van Wely, Luc J M Smits, Aafke P A van Montfoort, Sjoerd Repping, John C M Dumoulin, Sebastiaan Mastenbroek
No abstract text is available yet for this article.
December 29, 2016: Human Reproduction
https://www.readbyqxmd.com/read/28039226/birthweight-and-the-effects-of-culture-media
#19
LETTER
Jeremy Thompson, Michael Davies, Thomas Pool, Laura Rienzi, Peter Zsolt Nagy, Thorir Hardarson, Denny Sakkas, David Gardner
No abstract text is available yet for this article.
December 29, 2016: Human Reproduction
https://www.readbyqxmd.com/read/28039225/reply-i-embryo-culture-media-effects
#20
LETTER
Arne Sunde, Daniel Brison, John Dumoulin, Joyce Harper, Kersti Lundin, M Cristina Magli, Etienne Van den Abbeel, Anna Veiga
No abstract text is available yet for this article.
December 29, 2016: Human Reproduction
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