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Heart: Official Journal of the British Cardiac Society

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https://www.readbyqxmd.com/read/30415208/cardiac-biomarkers-predict-mortality-in-emergency-patients-presenting-with-atrial-fibrillation
#1
Jan Niederdöckl, Alexander Simon, Sebastian Schnaubelt, Nikola Schuetz, Roberta Laggner, Patrick Sulzgruber, Alexander O Spiel, Harald Herkner, Anton N Laggner, Hans Domanovits
OBJECTIVES: To assess the predictive value of N-terminal pro-brain natriuretic peptide (NT-proBNP) and high-sensitive troponin T (hs-TnT) serum levels for mid-term mortality in patients presenting with symptomatic atrial fibrillation (AF) to an emergency department. METHODS: Non-interventional cohort/follow-up study, including consecutive patients presenting to a tertiary care university emergency department due to symptomatic AF between 2012 and 2016. Multivariable Cox proportional hazard regression models were used to estimate the mortality rates and hazards per 100 patient-years (pry) for NT-proBNP and hs-TnT serum levels in quintiles...
November 10, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30415207/challenges-in-outlier-surgeon-assessment-in-the-era-of-public-reporting
#2
Jialin Mao, Frederic Scott Resnic, Leonard N Girardi, Mario Fl Gaudino, Art Sedrakyan
OBJECTIVE: To assess the effect of various evaluation and reporting strategies in determining outlier surgeons, defined by having worse-than-expected mortality after cardiac surgery. METHODS: Our study included 33 394 isolated coronary artery bypass graft (CABG) procedures performed by 136 surgeons and 12 172 surgical aortic valve replacement (SAVR) procedures performed by 113 surgeons between 2010 and 2014. Three current methodologies based on the framework of comparing observed and expected (O/E ratio) mortality, with different distributional assumptions, were examined...
November 10, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30415206/epidemiology-of-pericardial-diseases-in-africa-a-systematic-scoping-review
#3
REVIEW
Jean Jacques Noubiap, Valirie Ndip Agbor, Aude Laetitia Ndoadoumgue, Jan René Nkeck, Arnaud Kamguia, Ulrich Flore Nyaga, Mpiko Ntsekhe
OBJECTIVES: This scoping review sought to summarise available data on the prevalence, aetiology, diagnosis, treatment and outcome of pericardial disease in Africa. METHODS: We searched PubMed, Scopus and African Journals Online from 1 January 1967 to 30 July 2017 to identify all studies published on the prevalence, aetiologies, diagnosis, treatment and outcomes of pericardial diseases in adults residing in Africa. RESULTS: 36 studies were included...
November 10, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30415205/a-career-in-cardiology-why
#4
Clare Coyle, Holli Evans
No abstract text is available yet for this article.
November 10, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30415204/long-term-outcome-after-atrial-correction-for-transposition-of-the-great-arteries
#5
Lotte E Couperus, Hubert W Vliegen, Tjitske E Zandstra, Philippine Kiès, Monique R M Jongbloed, Eduard R Holman, Katja Zeppenfeld, Mark G Hazekamp, Martin J Schalij, Roderick W C Scherptong
OBJECTIVE: This study assessed adult survival and morbidity patterns in patients who underwent atrial correction according to Mustard or Senning for transposition of the great arteries (TGA). METHODS: In 76 adult patients with TGA (59% male) after atrial correction, long-term survival and morbidity were investigated in three periods: early (<15 years postoperatively), midterm (15-30 years postoperatively) and late (>30 years postoperatively). RESULTS: The Mustard technique was performed in 41 (54%) patients, and the Senning technique was performed in 35 (46%) patients aged 3...
November 10, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30415203/impact-of-heart-disease-on-maternal-fetal-and-neonatal-outcomes-in-a-low-resource-setting
#6
Andrea Beaton, Emmy Okello, Amy Scheel, Alyssa DeWyer, Renny Ssembatya, Olivia Baaka, Henrietor Namisanvu, Angela Njeri, Alphons Matovu, Imelda Namagembe, Robert Mccarter, Jonathan Carapetis, Kristen DeStigter, Craig Sable
BACKGROUND: The burden of pre-existing cardiovascular disease and the contribution to adverse pregnancy outcomes are not robustly quantified, particularly in low-income countries. We aimed to determine both the prevalence of maternal heart disease through active case finding and its attributable risk to adverse pregnancy outcomes. METHODS: We conducted a 24-month prospective longitudinal investigation in three Ugandan health centres, using echocardiography for active case finding during antenatal care...
November 10, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30381320/imaging-as-a-surrogate-marker-of-drug-efficacy-in-cardiovascular-disease
#7
Jason M Tarkin, Marc R Dweck, James H F Rudd
No abstract text is available yet for this article.
October 31, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30381319/sexual-rehabilitation-for-cardiac-patients-with-erectile-dysfunction-a-randomised-clinical-trial
#8
Pernille Palm, Ann-Dorthe Olsen Zwisler, Jesper Hastrup Svendsen, Lau Casper Thygesen, Annamaria Giraldi, Karina Gregersen Jensen, Jane Lindschou, Per Winkel, Christian Gluud, Elaine Steinke, Selina Kikkenborg Berg
BACKGROUND: Sexual dysfunction is common in patients with either ischaemic heart disease (IHD) or implantable cardioverter defibrillator (ICD) and has a negative impact on quality of life. Non-pharmacological treatment options are lacking. The purpose of this trial was to assess the effect of sexual rehabilitation versus usual care for males with erectile dysfunction and either IHD and/or ICD. METHODS: Participants with erectile dysfunction and IHD and/or ICD were randomised to 12 weeks of sexual rehabilitation consisting of physical exercise training, pelvic floor exercise and psychoeducation, or usual care...
October 31, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30377262/cardiac-output-changes-from-prior-to-pregnancy-to-post-partum-using-two-non-invasive-techniques
#9
Giulia Masini, Lin F Foo, Jérôme Cornette, Jasmine Tay, Dimitris Rizopoulos, Carmel M McEniery, Ian B Wilkinson, Christoph C Lees
OBJECTIVES: We aimed to describe cardiac output (CO) trend from prepregnancy to post partum using an inert gas rebreathing (IGR) device and compare these measurements with those obtained by a pulse waveform analysis (PWA) technique, both cross-sectionally and longitudinally. METHODS: Non-smoking healthy women, aged 18-44 years, with body mass index <35 were included in this prospective observational study. CO measurements were collected at different time points (prepregnancy, at four different gestational epochs and post partum) using IGR and PWA...
October 30, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30377261/national-trends-in-fontan-operation-and-in-hospital-outcomes-in-the-usa
#10
Emmanuel Akintoye, William R Miranda, Gruschen R Veldtman, Heidi M Connolly, Alexander C Egbe
BACKGROUND: National prevalence and outcomes of Fontan operation in the USA is unknown. Study objective was to determine trends (temporal change) in the annual volume of Fontan operations, in-hospital mortality, postoperative complications and type of hospital discharge. METHODS: Review of the Nationwide Inpatient Sample for patients that underwent Fontan operation from 2001 to 2014 using the International Classification of Diseases-Ninth Revision, Clinical Modification procedure code for Fontan operation, that is, 35...
October 30, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30377260/towards-cardiac-mri-based-risk-stratification-in-idiopathic-dilated-cardiomyopathy
#11
REVIEW
Pamela Frances Brown, Chris Miller, Andrea Di Marco, Matthias Schmitt
Sudden cardiac death (SCD) secondary to arrhythmia remains a risk in those with dilated cardiomyopathy (DCM), an implantable cardiac defibrillator (ICD) is an effective strategy to prevent SCD. Current guidelines recommend selection for ICD based on ejection fraction (EF) less than 35%, however, most SCD occurs in those with EF>35%. Although meta-analysis has demonstrated a survival benefit for primary prevention ICD in DCM, no randomised trial has shown a significant reduction in overall mortality including the most recent 'Danish Study to Assess the Efficacy of ICDs in Patients With Non-Ischemic Systolic Heat Failure on Mortality' study...
October 30, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30377259/cardiac-implantable-electronic-devices-in-adults-with-tetralogy-of-fallot
#12
Alexander C Egbe, William R Miranda, Malini Madhavan, Naser M Ammash, Venkata R Missula, Mohammed Al-Otaibi, Ayotola Fatola, Srikanth Kothapalli, Heidi M Connolly
BACKGROUND: Tachyarrhythmias and bradyarrhythmias affect 20%-50% of adult patients with tetralogy of Fallot (TOF) and some of these patients will require cardiac implantable electronic devices (CIED) such as pacemaker and/or internal cardioverter defibrillator. METHODS: The Mayo Adult Congenital Heart Disease database was queried for patients with repaired TOF and history of CIED implantation, 1990-2017. The study objectives were: (1) determine the occurrence of device-related complications defined as lead failure, lead recall, device infection and lead thrombus; and (2) determine the occurrence and risk factors for defibrillator shock...
October 30, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30368486/aortic-dilatation-and-outcome-in-women-with-turner-syndrome
#13
Anthonie L Duijnhouwer, Lidia R Bons, Henri J L M Timmers, Roland R L van Kimmenade, Miranda Snoeren, Janneke Timmermans, Allard T van den Hoven, Marlies Kempers, Arie P J van Dijk, Kathrin Fleischer, Jolien W Roos-Hesselink
BACKGROUND: Women with Turner syndrome (TS) are at increased risk of aortic dissection, which is related to ascending aortic diameter. However, the relation between aortic diameter and outcome is not well determined. This study evaluates the prevalence of aortic dilatation, the growth rate of the aorta and the risk of aortic complications in adults with TS. METHODS: Single centre, retrospective study of all women with TS followed with a strict protocol in an outpatient TS clinic...
October 27, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30368485/coronary-anatomy-in-turner-syndrome-versus-patients-with-isolated-bicuspid-aortic-valves
#14
Wilke M C Koenraadt, Hans-Marc J Siebelink, Margot M Bartelings, Martin J Schalij, Maureen J van der Vlugt, Annemien E van den Bosch, Ricardo P J Budde, Jolien W Roos-Hesselink, Anthonie L Duijnhouwer, Allard T van den Hoven, Marco C DeRuiter, Monique R M Jongbloed
OBJECTIVE: Variations in coronary anatomy, like absent left main stem and left dominant coronary system, have been described in patients with Turner syndrome (TS) and in patients with bicuspid aortic valves (BAV). It is unknown whether coronary variations in TS are related to BAV and to specific BAV subtypes. AIM: To compare coronary anatomy in patients with TS with/without BAV versus isolated BAV and to study BAV morphology subtypes in these groups. METHODS: Coronary anatomy and BAV morphology were studied in 86 patients with TS (20 TS-BAV, 66 TS-tricuspid aortic valve) and 86 patients with isolated BAV (37±13 years vs 42±15 years, respectively) by CT...
October 27, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30366935/effectiveness-of-the-2014-european-society-of-cardiology-guideline-on-sudden-cardiac-death-in-hypertrophic-cardiomyopathy-a-systematic-review-and-meta-analysis
#15
Constantinos O'Mahony, Mohammed Majid Akhtar, Zacharias Anastasiou, Oliver P Guttmann, Pieter A Vriesendorp, Michelle Michels, Damiano Magrì, Camillo Autore, Adrián Fernández, Juan Pablo Ochoa, Kevin M W Leong, Amanda M Varnava, Lorenzo Monserrat, Aristides Anastasakis, Pablo Garcia-Pavia, Claudio Rapezzi, Elena Biagini, Juan Ramon Gimeno, Giuseppe Limongelli, Rumana Z Omar, Perry M Elliott
OBJECTIVE: In 2014, the European Society of Cardiology (ESC) recommended the use of a novel risk prediction model (HCM Risk-SCD) to guide use of implantable cardioverter defibrillators (ICD) for the primary prevention of sudden cardiac death (SCD) in patients with hypertrophic cardiomyopathy (HCM). We sought to determine the performance of HCM Risk-SCD by conducting a systematic review and meta-analysis of articles reporting on the prevalence of SCD within 5 years of evaluation in low, intermediate and high-risk patients as defined by the 2014 guidelines (predicted risk <4%, 4%-<6% and ≥6%, respectively)...
October 26, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30366934/predictors-of-electrocardiographic-qt-interval-prolongation-in-men-with-hiv
#16
Katherine C Wu, Long Zhang, Sabina A Haberlen, Hiroshi Ashikaga, Todd T Brown, Matthew J Budoff, Gypsyamber D'Souza, Lawrence A Kingsley, Frank J Palella, Joseph B Margolick, Otoniel Martínez-Maza, Elsayed Z Soliman, Wendy S Post
OBJECTIVE: HIV-infected (HIV+) individuals may be at increased risk for sudden arrhythmic cardiac death. Some studies have reported an association between HIV infection and prolongation of the electrocardiographic QT interval, a measure of ventricular repolarisation, which could potentiate ventricular arrhythmias. We aimed to assess whether HIV+ men have longer QT intervals than HIV-uninfected (HIV-) men and to determine factors associated with QT duration. METHODS: We performed resting 12-lead ECGs in 774 HIV+ and 652 HIV- men in the Multicenter AIDS Cohort Study (MACS)...
October 26, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30361271/inverse-association-of-pulse-pressure-augmentation-during-exercise-with-heart-failure-and-death
#17
Mahmoud Al Rifai, Michael J Blaha, Faisal Rahman, Jonathan K Ehrman, Clinton A Brawner, Steven J Keteyian, Mouaz H Al-Mallah, John William McEvoy
OBJECTIVE: Resting pulse pressure (PP) is a risk factor for heart failure (HF); however, whether PP augmentation during exercise, a parameter easily obtained from routine treadmill stress testing, is associated with incident HF is unknown. Thus, we aimed to study the relationship between a novel parameter, the pulse pressure stress index (P2SI), and adverse outcomes among adults undergoing clinical exercise stress testing in the Henry Ford Exercise Testing Project. METHODS: The P2SI was calculated as PP at peak exercise divided by resting PP and was analysed continuously and categorically using quartiles...
October 25, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30361270/out-of-hospital-initiation-of-hypothermia-in-st-segment-elevation-myocardial-infarction-a-randomised-trial
#18
Christoph Testori, Dietrich Beitzke, Andreas Mangold, Fritz Sterz, Christian Loewe, Christoph Weiser, Thomas Scherz, Harald Herkner, Irene Lang
OBJECTIVE: To evaluate the effect of prereperfusion hypothermia initiated in the out-of-hospital setting in awake patients with ST-segment elevation myocardial infarction (STEMI) on myocardial salvage measured by cardiac MRI (CMR). METHODS: Hypothermia was initiated within 6 hours of symptom onset by the emergency medical service with surface cooling pads and cold saline, and continued in the cath lab with endovascular cooling (target temperature: ≤35°C at time of reperfusion)...
October 25, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30361269/broken-hearts-and-bones-new-insights-or-falling-for-unmeasured-confounding
#19
EDITORIAL
Joshua R Lewis, Pawel Szulc
No abstract text is available yet for this article.
October 25, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30343285/prognostic-impact-of-peak-mitral-inflow-velocity-in-asymptomatic-degenerative-mitral-regurgitation
#20
Chisato Okamoto, Atsushi Okada, Hideaki Kanzaki, Kunihiro Nishimura, Yasuhiro Hamatani, Masashi Amano, Hiroyuki Takahama, Makoto Amaki, Takuya Hasegawa, Tomoyuki Fujita, Junjiro Kobayashi, Satoshi Yasuda, Chisato Izumi
OBJECTIVE: Appropriate timing of mitral valve surgery in asymptomatic mitral regurgitation (MR) remains controversial. Peak mitral inflow velocity (peak E wave velocity) has been reported as a simple and easy predictor of quantitative MR severity; however, its prognostic significance in asymptomatic MR remains unclear. Therefore, we sought to investigate the prognostic impact of peak E wave velocity in asymptomatic MR. METHODS: Among 529 consecutive patients with degenerative MR of grade 3+ (moderate to severe) or 4+ (severe), 188 asymptomatic patients in sinus rhythm without left ventricular (LV) dysfunction (end-systolic dimension ≥40 mm or ejection fraction <60%) or pulmonary hypertension were studied...
October 20, 2018: Heart: Official Journal of the British Cardiac Society
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