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Gastrointestinal Endoscopy

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https://www.readbyqxmd.com/read/29133196/cold-endoscopic-mucosal-resection-of-large-sessile-serrated-polyps-at-colonoscopy-with-video
#1
Nicholas J Tutticci, David G Hewett
BACKGROUND AND AIMS: The optimal technique for the resection of sessile serrated polyps (SSPs) is unknown, with established limitations and risks with conventional polypectomy. Although cold snare polypectomy is safe, the efficacy of piecemeal resection for large lesions is untested. In this study, we evaluate the safety and efficacy of cold endoscopic mucosal resection (EMR) for large SSPs. METHODS: Patients presenting for elective colonoscopy at an academic endoscopy center with 1 or more SSPs ≥10mm in size were enrolled, excluding those on anticoagulants or antiplatelets other than aspirin...
November 10, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29129525/multicenter-evaluation-of-the-clinical-utility-of-laparoscopy-assisted-ercp-in-patients-with-roux-en-y-gastric-bypass
#2
Ali M Abbas, Andrew T Strong, David L Diehl, Brian C Brauer, Iris H Lee, Rebecca Burbridge, Jaroslav Zivny, Jennifer T Higa, Marcelo Falcão, Ihab I El Hajj, Paul Tarnasky, Brintha K Enestvedt, Alexander R Ende, Adarsh M Thaker, Rishi Pawa, Priya Jamidar, Kartik Sampath, Eduardo Guimarães Hourneaux de Moura, Richard S Kwon, Alejandro L Suarez, Murad Aburajab, Andrew Y Wang, Mohammad H Shakhatreh, Vivek Kaul, Lorna Kang, Thomas E Kowalski, Rahul Pannala, Jeffrey Tokar, A Aziz Aadam, Demetrios Tzimas, Mihir S Wagh, Peter V Draganov, M D The LA-Ercp Research Group Jeffrey Ponsky, Bruce D Greenwald, Lance T Uradomo, Alyson A McGhan, Shahrad Hakimian, Andrew Ross, Stuart Sherman, Benjamin L Bick, Christopher E Forsmark, Dennis Yang, Anand Gupte, Shailendra Chauhan, Steven J Hughes, Karen Saks, Gennadiy Bakis, Adam W Templeton, Michael Saunders, Alireza Sedarat, John A Evans, Thiruvengadam Muniraj, Timothy B Gardner, Almino C Ramos, Marco Aurelio Santo, Andrew Nett, Gregory A Coté, B Joseph Elmunzer, Kulwinder S Dua, Michael J Nosler, Daniel S Strand, Paul Yeaton, Shivangi Kothari, Asad Ullah, Pushpak Taunk, Patrick Brady, Haim Pinkas, Ashley L Faulx, Haroon Shahid, Jordan Holmes, Davinderbir Pannu, Srinadh Komanduri, Juan Carlos Bucobo, Harry Dhaliwal, Alaa Rostom, Brent W Acker
BACKGROUND AND AIMS: The obesity epidemic has led to increased use of Roux-en-Y gastric bypass (RYGB). These patients have an increased incidence of pancreaticobiliary diseases yet standard ERCP is not possible due to surgically altered gastroduodenal anatomy. Laparoscopic-ERCP (LA-ERCP) has been proposed as an option but supporting data are derived from single center small case-series. Therefore, we conducted a large multicenter study to evaluate the feasibility, safety, and outcomes of LA-ERCP...
November 9, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29128386/a-pilot-study-of-endoscopically-inserted-biodegradable-biliary-stents-in-the-treatment-of-benign-biliary-strictures-and-cystic-duct-leaks
#3
Antti Siiki, Irina Rinta-Kiikka, Juhani Sand, Johanna Laukkarinen
BACKGROUND AND AIMS: Self-expanding biodegradable biliary stents (BDBSs) have recently become available for use in endoscopic retrograde cholangiography (ERC). The aim was to evaluate the effectiveness and safety of novel BDBS in iatrogenic cystic duct leaks and benign biliary strictures (BBSs). MATERIALS AND METHODS: Patients providing informed consent were recruited for the prospective study. Braided self-expanding poly-dioxanone BDBSs were inserted in ERC during the period 2012 to 2016...
November 8, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29122604/clinical-predictors-of-histological-type-of-gastric-cancer
#4
Takashi Kanesaka, Takashi Nagahama, Noriya Uedo, Hisashi Doyama, Tetsuya Ueo, Kunihisa Uchita, Naohiro Yoshida, Yasuhito Takeda, Kentaro Imamura, Kurato Wada, Hideki Ishikawa, Kenshi Yao
BACKGROUND AND AIMS: Gastric cancer is classified into differentiated and undifferentiated types according to the degree of glandular differentiation. Undifferentiated-type early gastric cancer (EGC) carries a higher risk of lymph node metastasis than differentiated type, and the indication criteria for endoscopic resection thus differ. This study aimed to clarify the diagnostic abilities of clinical predictors to distinguish between differentiated-type and undifferentiated-type EGCs...
November 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29122603/the-role-of-colorectal-endoscopic-submucosal-dissection-in-patients-with-ulcerative-colitis
#5
Satoshi Kinoshita, Toshio Uraoka, Toshihiro Nishizawa, Makoto Naganuma, Yasushi Iwao, Yasutoshi Ochiai, Ai Fujimoto, Osamu Goto, Masayuki Shimoda, Haruhiko Ogata, Takanori Kanai, Naohisa Yahagi
BACKGROUND AND AIM: Patients with ulcerative colitis have an increased risk of colorectal dysplasia. Endoscopic submucosal dissection (ESD) for the neoplastic lesions in ulcerative colitis remains controversial. The aim of this study was to clarify the role of ESD in treatment strategy for ulcerative colitis. METHODS: We retrospectively investigated 25 patients with ulcerative colitis in clinical remission who underwent colorectal ESD at two referral centers. We analyzed short-term and long-term outcomes...
November 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29122602/utility-of-multi-detector-ct-scans-after-colorectal-endoscopic-submucosal-dissection-a-prospective-study
#6
Ryosuke Kobayashi, Kingo Hirasawa, Chiko Sato, Makomo Makazu, Hiroaki Kaneko, Ryosuke Ikeda, Takehide Fukuchi, Atsushi Sawada, Yuichiro Ozeki, Masataka Taguri, Shigeo Takebayashi, Maeda Shin
BACKGROUND AND AIMS: Several reports have described the major adverse events after endoscopic submucosal dissection (ESD), such as perforation or bleeding. However, few studies have discussed the occurrence of post-ESD electrocoagulation syndrome (PEECS) after colorectal ESD. Additionally, the occurrence of fever without abdominal pain in patients requires postoperative management similar to that required for PEECS. Therefore, we have defined post-ESD inflammatory syndrome (PEIS) as composed of both PEECS and fever without abdominal pain...
November 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29122601/per-oral-endoscopic-myotomy-in-patients-with-or-without-prior-heller-myotomy-comparing-long-term-outcomes-in-a-large-u-s-single-center-cohort-with-videos
#7
Xiaocen Zhang, Rani J Modayil, David Friedel, Krishna C Gurram, Collin E Brathwaite, Sharon I Taylor, Maria M Kollarus, Sony Modayil, Bhawna Halwan, James H Grendell, Stavros N Stavropoulos
BACKGROUND AND AIMS: Heller myotomy (HM) is one of the most effective treatments for esophageal achalasia. However, failures do exist and the success rate tends to decrease with time. The efficacy of rescue treatments for patients with failed Heller is limited. A few small-scale studies have reported outcomes of per-oral endoscopic myotomy (POEM) in these patients. We conducted this study to systematically assess feasibility, safety, and efficacy of POEM on post-Heller patients. METHODS: Patients at least 3 months out from their POEM were selected from our prospective database: 318 consecutive POEMs performed from October 2009 to October 2016...
November 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29122600/width-and-depth-of-resection-for-small-colorectal-polyps-hot-versus-cold-snare-polypectomy
#8
Sho Suzuki, Takuji Gotoda, Chika Kusano, Hisatomo Ikehara, Akihiro Sugita, Misa Yamauchi, Mitsuhiko Moriyama
BACKGROUND AND AIMS: Curability is associated with resection width and depth in polypectomy. We evaluated the resection width and depth achieved with hot snare polypectomy (HSP) and cold snare polypectomy (CSP) for small colorectal polyps. METHODS: In this single-center, prospective, randomized controlled study, patients with rectal or rectosigmoid polyps ≤10 mm in diameter were treated with HSP or CSP. Resection width was evaluated as mucosal defect size, measured immediately postprocedure and 1 day later...
November 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29122599/impact-of-experience-on-self-assessment-accuracy-of-clinical-colonoscopy-competence
#9
Michael A Scaffidi, Samir C Grover, Heather Carnahan, Rishad Khan, Jennifer M Amadio, Jeffrey J Yu, Callum Dargavel, Nitin Khanna, Simon C Ling, Elaine Yong, Geoffrey C Nguyen, Catharine M Walsh
BACKGROUND AND AIMS: Self-assessment is important for life-long learning and a recommended assessment method for endoscopy skills. Prior literature has not investigated self-assessment accuracy of colonoscopic competence in the clinical setting. This study aimed to determine the self-assessment accuracy of novice, intermediate, and experienced endoscopists. METHODS: Novice (performed <50 previous colonoscopies), intermediate (50-500), and experienced (>1000) endoscopists from 5 hospitals each performed a clinical colonoscopy...
November 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29122598/effects-of-eus-guided-intratumoral-injection-of-oligonucleotide-stnm01-on-tumor-growth-histology-and-overall-survival-in-patients-with-unresectable-pancreatic-cancer
#10
Makoto Nishimura, Miho Matsukawa, Yuko Fujii, Yoko Matsuda, Tomio Arai, Yasutoshi Ochiai, Takao Itoi, Naohisa Yahagi
BACKGROUND AND AIMS: Carbohydrate sulfotransferase 15 (CHST15) promotes tumor growth and invasion and is considered to be an emergent therapeutic target for pancreatic cancer. The aim of this study was to evaluate the safety and efficacy of EUS-guided fine-needle injection (EUS-FNI) of STNM01, the double-stranded RNA oligonucleotide that specifically represses CHST15, for use in patients with pancreatic cancer. METHODS: Six patients with unresectable pancreatic cancer, treated at Tokyo Metropolitan Geriatric Hospital, were used in this open-labeled, investigator-initiated trial...
November 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29122597/upper-gi-involvement-in-children-with-familial-adenomatous-polyposis-syndrome-single-center-experience-and-meta-analysis-of-the-literature
#11
Luz H Gutierrez Sanchez, Mouaz Alsawas, Michael Stephens, Mohammad Hassan Murad, Imad Absah
BACKGROUND AND AIMS: Familial adenomatous polyposis (FAP) is a hereditary syndrome that can affect the entire GI tract. Current screening recommendations include esophagogastroduodenoscopy (EGD) starting at age 25 to 30 years or earlier in symptomatic patients. However, there are few reports describing upper GI tract involvement in children with FAP which support the notion of early screening. The aim of our study is to understand the prevalence and severity of upper GI involvement in children with FAP...
November 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29113789/a-case-of-lymphangioma-like-mesenteric-cysts-diagnosed-as-adenocarcinoma-of-possible-pancreatic-origin-on-eus-fna
#12
Maxime Delvincourt, Edmund M Godfrey, Adam Duckworth, Nicholas R Carroll
No abstract text is available yet for this article.
November 4, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29108984/transoral-outlet-reduction-a-comparison-of-pursestring-to-interrupted-stitch-technique
#13
Allison R Schulman, Nitin Kumar, Christopher C Thompson
BACKGROUND AND AIMS: Weight regain after Roux-en-Y gastric bypass (RYGB) correlates with dilated gastrojejunal anastomosis (GJA). Endoscopic sutured transoral outlet reduction (TORe) is safe and effective in the management, and has predominantly been performed by either (1) placing interrupted sutures at the GJA or (2) the creation of a pursestring. The aim of the current study was to compare these techniques. METHODS: All patients undergoing TORe using for weight regain after RYGB were prospectively enrolled...
November 3, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29108983/a-novel-device-for-improving-visualization-in-an-inadequately-prepared-colon
#14
Seth Gross, Lauren Gerson, Blair Lewis, Robert Ganz
BACKGROUND AND AIMS: Adequate bowel preparation is essential for a quality colonoscopy. Poor bowel preparation can result in longer procedural times, missed adenomas, earlier repeat procedures, increase costs, and decreased patient satisfaction [1-5]. Pure-Vu (MOTUS GI, Tirat Carmel, Israel) is a system that facilitates intra-procedural cleaning of a poorly prepared colon during a colonoscopy by irrigating the colon and evacuating the fluid and feces. The study aims were to evaluate Pure-Vu's cleansing capabilities and its usability and safety, in a live animal colon METHODS: The Pure-Vu system was used by four experienced gastroenterologists in 35 Yorkshire cross swine (66% female) that received a reduced bowel preparation to ensure an inadequate bowel preparation at baseline...
November 3, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29108982/eosinophilic-gastritis-with-involvement-of-esophageal-gastric-inlet-patch
#15
David G Forcione, Gregory Y Lauwers, John J Garber
No abstract text is available yet for this article.
November 3, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29108981/outcomes-of-per-oral-endoscopic-myotomy-for-treatment-of-esophageal-achalasia-with-a-median-follow-up-of-49-months
#16
Quan-Lin Li, Qiu-Ning Wu, Xiao-Cen Zhang, Mei-Dong Xu, Wei Zhang, Shi-Yao Chen, Yun-Shi Zhong, Yi-Qun Zhang, Wei-Feng Chen, Wen-Zheng Qin, Jian-Wei Hu, Ming-Yan Cai, Li-Qing Yao, Ping-Hong Zhou
BACKGROUND AND AIMS: Per-oral endoscopic myotomy (POEM) has received wide acceptance as a highly effective and safe treatment for esophageal achalasia. Short-term and small-scale studies are ample but long-term large-scale studies are few. The aim of the study was to systematically analyze our long-term results of POEM, with particular emphasis on POEM failures and associated risk factors. METHODS: This is a single-center study. Consecutive POEM patients between August 2010 and December 2012 were included...
November 3, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29108980/radiofrequency-ablation-combined-with-biliary-stent-placement-versus-stent-placement-alone-for-malignant-biliary-strictures-a-systematic-review-and-meta-analysis
#17
REVIEW
Aijaz Ahmed Sofi, Muhammad Ali Khan, Ananya Das, Mankanwal Sachdev, Sadik Khuder, Ali Nawras, Wade Lee
Unresectable malignant biliary strictures are generally managed by palliative stent placement for drainage of biliary tree. Recently, radiofrequency ablation (RFA) has been used to improve the patency of biliary stents in these patients. Several studies have evaluated the effectiveness of biliary stent placement with RFA on stent patency and patient survival with variable results. We performed this meta-analysis to evaluate the efficacy and safety of biliary stent placement with RFA compared with stent placement alone in patients with malignant biliary strictures...
November 3, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29108979/prediction-of-clinical-outcomes-in-crohn-s-disease-by-using-confocal-laser-endomicroscopy-results-from-a-prospective-multicenter-study
#18
Gian Eugenio Tontini, Jonas Mudter, Michael Vieth, Claudia Günther, Valentina Milani, Raja Atreya, Timo Rath, Andreas Nägel, Giorgia Hatem, Giacomo Carlo Sturniolo, Maurizio Vecchi, Markus F Neurath, Peter R Galle, Andrea Buda, Helmut Neumann
BACKGROUND & AIMS: Assessment of prognostic factors in Crohn's disease (CD) patients is of pivotal importance for early intervention and "treat-to-target" strategies. Confocal Laser Endomicroscopy (CLE) enables on demand in vivo characterization of mucosal inflammatory and architectural changes during endoscopy. We prospectively assessed the value of CLE for prediction of clinical outcome parameters in CD. METHODS: Consecutive patients with CD undergoing colonoscopy were included in a multicentre study...
November 3, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29108978/volume-of-surgery-for-benign-colorectal-polyps-in-the-last-11-years
#19
Maxime E S Bronzwaer, Lianne Koens, Willem A Bemelman, Evelien Dekker, Paul Fockens
INTRODUCTION: Traditionally large complex colorectal polyps were managed by surgical resection (SR) and in recent years endoscopic resection (ER) has progressed significantly. However, to what extent ER has replaced SR remains largely unknown. We performed a multicenter retrospective cohort study to assess the volume and volume changes of SR for benign colorectal polyps over the past decade. METHODS: Patients who underwent SR for a benign colorectal polyp in the Netherlands between 2005 and 2015 were selected from the prospective nationwide Dutch Pathology Registry...
November 3, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29102736/gastric-adenocarcinoma-of-the-fundic-gland-chief-cell-predominant-type-with-brownish-pigmentation
#20
Atsushi Imagawa, Nobuya Sano
No abstract text is available yet for this article.
November 1, 2017: Gastrointestinal Endoscopy
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