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Gastrointestinal Endoscopy

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https://www.readbyqxmd.com/read/28193491/linked-color-imaging-improves-endoscopic-visibility-of-colorectal-nongranular-flat-lesions
#1
Takuto Suzuki, Taro Hara, Yoshiyasu Kitagawa, Hideyuki Takashiro, Rino Nankinzan, Osamu Sugita, Taketo Yamaguchi
BACKGROUND AND AIMS: As a newly developed image-enhanced endoscopy (IEE) technique, linked-color imaging (LCI) provides very bright images with enhanced color tones. With the objective of improving the detection rate of colorectal flat tumor lesions, which are difficult to detect, we examined the usefulness of LCI from the viewpoint of visibility. METHODS: Fifty-three consecutive nongranular flat tumors were used in this study. Endoscopic images were acquired by white-light imaging (WLI), blue-laser imaging (BLI)-bright, and LCI modes...
February 10, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28189635/medical-endoscopic-and-surgical-management-of-ileal-pouch-strictures-with-video
#2
REVIEW
Shishira Bharadwaj, Bo Shen
The construction of ileal pouch-anal anastomosis (IPAA) is the procedure of choice for patients with ulcerative colitis or familial adenomatous polyposis, who require colectomy. Furthermore, IPAA has the advantage of preserving the natural route of defecation unlike the Brooke's ileostomy or continent ileostomies. On the other hand, the natural history of patients with the ileal pouch can be complicated by various surgical-procedure-associated mechanical adverse events as well as inflammatory and functional disorders...
February 8, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28188723/eus-guided-celiac-ganglia-neurolysis-a-clinical-and-human-cadaver-study-with-video
#3
Wouter F W Kappelle, Ronald L A W Bleys, Albert J M van Wijck, Peter D Siersema, Frank P Vleggaar
BACKGROUND AND AIMS: There is little evidence that structures targeted during EUS-guided celiac ganglia neurolysis (EUS-CGN) are celiac ganglia and that selective ethanol injection into ganglia is feasible. We aimed to visualize celiac ganglia, confirm that these structures are ganglia, and visualize ethanol spread after EUS-CGN and EUS-guided celiac plexus neurolysis (EUS-CPN). METHODS: First, celiac ganglia were sought during 97 consecutive EUS procedures. Second, ganglia were identified in a prosected human cadaver by placing a linear echo-endoscope next to the celiac trunk and the underlying tissue was removed for histology...
February 7, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28188722/prevalence-of-hypokalemia-before-and-after-bowel-preparation-for-colonoscopy-in-high-risk-patients
#4
Ankie Reumkens, Ad A M Masclee, Bjorn Winkens, Cees T van Deursen, Silvia Sanduleanu, C Minke Bakker
BACKGROUND AND AIMS: Bowel preparation for colonoscopy should not cause significant shifts in systemic electrolyte concentrations. We recently encountered 2 cases of severe postcolonoscopy hypokalemia with fatal consequences, prompting us to conduct a study to explore the magnitude of and risk factors for hypokalemia associated with bowel preparation. We paid specific attention to higher risk subgroups, in particular diuretic users, hospitalized patients and patients estimated at to be high risk by the gastroenterologist...
February 7, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28185905/a-preliminary-study-of-single-operator-cholangioscopy-for-diagnosing-pancreatic-cystic-lesions
#5
Chai Ning-Li, Feng Jia, Guo Yu-Hang, Li Hui-Kai, Ning Bo Wang, Xiangdong Wang, Wang Ying, Wang Yong-Hua, Zhai Ya-Qi, Linghu En-Qiang
BACKGROUND AND AIMS: Advances in imaging technology have improved the annual detection rate of pancreatic cystic lesions, but the preoperative diagnosis of pancreatic cystic lesions remains unclear. Thus, the usefulness of single operator cholangioscopy (SOC) as a diagnostic imaging tool for pancreatic cystic lesions is worth investigating. We performed an intracystic visual examination of pancreatic cystic lesions using SOC to determine the diagnostic value of SOC for pancreatic cystic lesions...
February 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28174126/accuracy-of-asge-high-risk-criteria-in-evaluation-of-patients-with-suspected-common-bile-duct-stones
#6
Huiqin He, Chenfei Tan, Jiaguo Wu, Ning Dai, Weiling Hu, Yawen Zhang, Loren Laine, James Scheiman, John J Kim
BACKGROUND AND AIMS: Endoscopic retrograde cholangiopancreatography (ERCP) is recommended for patients considered high-risk for choledocholithiasis after biochemical testing and abdominal ultrasound. Our aim was to determine whether American Society for Gastrointestinal Endoscopy (ASGE) guidelines accurately select patients where the risk of ERCP is justified. METHODS: Consecutive patients hospitalized with suspected choledocholithiasis at Sir Run Run Shaw Hospital who received biochemical testing, abdominal ultrasound, and definitive testing for choledocholithiasis (magnetic resonance cholangiopancreatography (MRCP), endoscopic ultrasound (EUS), ERCP, intraoperative cholangiogram (IOC), common bile duct (CBD) exploration) were identified...
February 4, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28174125/family-history-in-colonoscopy-patients-feasibility-and-performance-of-electronic-and-paper-based-surveys-for-colorectal-cancer-risk-assessment-in-the-outpatient-setting
#7
Tannaz Guivatchian, Erika S Koeppe, Jason R Baker, Cristina Moisa, Matthew Demerath, Caitlin Foor-Pessin, William D Chey, Shanti L Eswaran, Joseph C Kolars, Stacy B Menees, Michael Rajala, Michael D Rice, Rafat Rizk, Joel H Rubenstein, Pratima Sharma, Andrea Todisco, Elena M Stoffel
BACKGROUND AND AIMS: Family history is crucial in stratifying patients' risk for colorectal cancer (CRC). Previous risk assessment tools developed for use in clinic or endoscopy settings have demonstrated suboptimal specificity for identifying patients with hereditary cancer syndromes. Our aim was to test the feasibility and performance of 2 family history surveys (paper and electronic) in individuals presenting for outpatient colonoscopy. METHODS: Patients presenting for outpatient colonoscopy at a tertiary care center were asked to complete a 5 question paper risk assessment survey (short paper survey) either alone or in conjunction with a second, comprehensive electronic family risk assessment survey (comprehensive tablet survey)...
February 4, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28174124/endoscopic-treatment-outcomes-of-laterally-spreading-tumors-with-a-skirt-with-video
#8
Shozo Osera, Hiroaki Ikematsu, Satoshi Fujii, Keisuke Hori, Yasuhiro Oono, Tomonori Yano, Kazuhiro Kaneko
BACKGROUND AND AIMS: A "skirt" is a slightly elevated flat lesion with wide pits occasionally observed at the margin of laterally spreading tumors (LSTs). However, the endoscopic treatment outcomes of LSTs with skirts have not been clarified. The aim of this study was to evaluate the endoscopic treatment outcomes of LSTs with skirts. METHODS: Between February 2006 and March 2014, 996 LSTs were retrospectively examined to assess the clinicopathological characteristics, procedure time, en bloc resection rate, R0 resection rate, adverse events, and local recurrence rate of endoscopic submucosal dissection (ESD); and the local recurrence rate of endoscopic resection...
February 4, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28174123/urgent-colonoscopy-in-patients-with-lower-gastrointestinal-bleeding-a-systematic-review-and-meta-analysis
#9
REVIEW
Abdul M Kouanda, Ma Somsouk, Justin L Sewell, Lukejohn W Day
BACKGROUND AND AIMS: Lower GI bleeding is a common cause of morbidity and mortality. Colonoscopy is indicated in all hospitalized patients with lower gastrointestinal bleeding, yet the time frame for performing colonoscopy remains unclear. Prior studies of outcomes in urgent versus elective colonoscopy have yielded conflicting results and were often underpowered. Our study objective was to compare several outcomes between urgent and elective colonoscopy in patients hospitalized for lower GI bleeding...
February 4, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28167119/endoscopic-optical-coherence-tomography-angiography-microvascular-features-associated-with-dysplasia-in-barrett-s-esophagus-a-pilot-study-with-video
#10
Hsiang-Chieh Lee, Osman O Ahsen, Kaicheng Liang, Zhao Wang, Marisa Figueiredo, Michael G Giacomelli, Benjamin Potsaid, Qin Huang, Hiroshi Mashimo, James G Fujimoto
BACKGROUND AND AIMS: Angiogenesis is associated with neoplastic progression of Barrett's esophagus (BE). Volumetric optical coherence tomography angiography (OCTA) visualizes subsurface microvasculature without exogenous contrast agents. We investigated the association of OCTA microvascular features with low-grade dysplasia (LGD) and high-grade dysplasia (HGD). METHODS: Fifty-two patients undergoing BE surveillance or endoscopic eradication therapies for dysplasia were imaged using volumetric OCTA and corresponding histological diagnoses obtained, to yield 97 data sets (non-dysplastic BE (NDBE): N=74; LGD: N=10; HGD: N=13)...
February 3, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28167118/indomethacin-and-diclofenac-in-the-prevention-of-post-ercp-pancreatitis-a-systematic-review-and-meta-analysis-of-prospective-controlled-trials
#11
REVIEW
Árpád Patai, Norbert Solymosi, László Mohácsi, Árpád V Patai
BACKGROUND AND AIMS: Diclofenac and indomethacin are the most studied drugs for preventing post-ERCP pancreatitis (PEP). However, there are no prospective, randomized multicenter trials with sufficient number of patients for the correct evaluation of their efficacy. Our aim was to evaluate of all trials published in full text and studied efficacy of diclofenac or indomethacin prospective controlled with placebo or non-treatment for the prevention of PEP in adult patients undergoing ERCP...
February 3, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28161451/feasibility-of-laser-marking-in-barrett-s-esophagus-with-volumetric-laser-endomicroscopy-first-in-man-pilot-study
#12
A Swager, A J de Groof, S L Meijer, B L Weusten, W L Curvers, J J Bergman
BACKGROUND AND AIM: Volumetric laser endomicroscopy (VLE) provides a circumferential scan of the esophageal wall layers, and has potential to improve neoplasia detection in Barrett's esophagus (BE). The novel VLE laser marking system enables direct in vivo marking of suspicious areas as identified on VLE. These laser marked areas can subsequently be targeted for biopsies. The aim was to evaluate the visibility and positional accuracy of laser marks in different esophageal tissue types on white-light endoscopy (WLE) and VLE...
February 1, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28161450/standard-needle-versus-needleless-injection-modality-animal-study-on-different-fluids-for-submucosal-elevation
#13
Alessandro Repici, Roberta Maselli, Silvia Carrara, Andrea Anderloni, Markus Enderle, Cesare Hassan
BACKGROUND AND AIMS: Submucosal injection is currently used in GI endoscopy to reduce resection risks and to perform submucosal dissection; it is usually performed via an injection needle or via a needleless device. The aim of the study was to compare 2 submucosal injection modalities (needle-assisted vs needleless) by using substances with different viscosities METHODS: Needle and needleless injections were compared by assessing the efficacy of tissue elevation with 5 different substances in an ex vivo porcine model...
February 1, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28161449/outcomes-and-quality-of-life-assessment-after-gastric-per-oral-endoscopic-pyloromyotomy-with-video
#14
Sunil Dacha, Parit Mekaroonkamol, Lianyong Li, Nikrad Shahnavaz, Sonali Sakaria, Steven Keilin, Field Willingham, Jennifer Christie, Qiang Cai
BACKGROUND AND AIM: Gastric per-oral endoscopic pyloromyotomy (GPOEM) is emerging as a promising option for the treatment of gastroparesis. This study assessed outcomes and quality-of-life after GPOEM for gastroparesis, performed in an endoscopy unit at a major tertiary referral center. METHODS: We performed a retrospective review of patients who had undergone GPOEM during June 2015 to July 2016. Data were collected from electronic medical records including patient demographics, endoscopy records, hospitalization records, clinic visits, and electronic messages...
February 1, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28159540/complex-early-barrett-s-neoplasia-at-3-western-centers-european-barrett-s-endoscopic-submucosal-dissection-trial-e-best
#15
Sharmila Subramaniam, Fergus Chedgy, Gaius Longcroft Wheaton, Kesavan Kandiah, Roberta Maselli, Stefan Seewald, Alessandro Repici, Pradeep Bhandari
BACKGROUND AND AIMS: Endoscopic submucosal dissection (ESD) is an effective technique to resect early Barrett's neoplasia and has advantages over conventional endoscopic mucosal resection (EMR) as it enables en bloc resection and accurate histopathological analysis of cancer resection margins. However, its long learning curve and higher adverse event rate has tempered its uptake in the West. We aimed to analyze the safety and efficacy of ESD when used to resect complex Barrett's neoplasia...
January 31, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28159539/continued-midazolam-versus-diphenhydramine-in-difficult-to-sedate-patients-a-randomized-double-blind-trial
#16
Hamita Sachar, Nipaporn Pichetshote, Kavitha Nandigam, Keta Vaidya, Loren Laine
BACKGROUND AND AIMS: Current guidelines recommend diphenhydramine in patients undergoing endoscopy who are not adequately sedated with a benzodiazepine and opioid combination. Because this practice has not been adequately assessed, we performed a randomized, double-blind trial comparing diphenhydramine to continued midazolam in such patients. METHODS: Patients undergoing elective colonoscopy with moderate sedation were eligible. Sedation was measured with the modified observer's assessment of alertness/sedation (MOAA/S) score with adequate sedation defined as 3 on a 0 to 5 scale...
January 31, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28153572/exploring-endoscopic-therapy-for-the-treatment-of-crohn-s-disease-related-fistula-and-abscess
#17
REVIEW
Bo Shen
Fistula and abscess represents penetrating disease phenotype of Crohn's disease (CD), and they can develop in patients with or without prior history of CD-related surgery. Although CD fistula and abscess have been traditionally treated with medical and surgical therapy, the role of endoscopic therapy in this particularly phenotype of CD is expanding recently, thanks to advanced endoscopic techniques and our better understanding of pathogenesis and natural history of the disease and principle of treatment. The success of endoscopic treatment for IBD depends upon comprehension and appreciation of principles, then techniques, followed by instrument and device...
January 31, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28153569/oral-administration-of-conditioned-medium-obtained-from-mesenchymal-stem-cell-culture-prevents-subsequent-stricture-formation-after-esophageal-submucosal-dissection-in-pigs
#18
Takeshi Mizushima, Shunsuke Ohnishi, Hidetaka Hosono, Kenichi Yamahara, Momoko Tsuda, Yuichi Shimizu, Mototsugu Kato, Masahiro Asaka, Naoya Sakamoto
BACKGROUND AND AIMS: Endoscopic submucosal dissection (ESD) for esophageal cancer often causes postoperative stricture when more than three-quarters of the circumference of the esophagus is dissected. Mesenchymal stem cells are a valuable cell source in regenerative medicine, and conditioned medium (CM) obtained from mesenchymal stem cells reportedly inhibits inflammation. In this study, we evaluated whether CM could prevent esophageal stricture after ESD. METHODS: We resected a semi-circumference of pig esophagus by ESD...
January 31, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28153571/providing-data-for-serrated-polyp-detection-rate-benchmarks-an-analysis-of-the-new-hampshire-colonoscopy-registry
#19
Joseph C Anderson, Lynn F Butterly, Julia E Weiss, Christina M Robinson
BACKGROUND AND AIMS: Similar to achieving adenoma detection rate (ADR) benchmarks to prevent colorectal cancer (CRC), achieving adequate serrated polyp detection rates (SDR) may be essential to the prevention of CRC associated with the serrated pathway. Previous studies have been based on data from high-volume endoscopists at single academic centers. Based on a hypothesis that ADR is correlated with SDR, we stratified a large, diverse group of endoscopists (n=77 practicing at 28 centers) into high and low performers based on ADR, to provide data for corresponding target SDR benchmarks...
January 30, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28153570/gender-disparities-in-gastroenterology-fellowship-director-positions-in-the-united-states
#20
Zibing Woodward, Zaida Rodriguez, Janice Jou, Kian Keyashian, Yiyi Chen, Charles R Thomas, Grace H Elta, Sharlene L D'Souza
BACKGROUND AND AIMS: Despite a paucity of women occupying leadership positions in academic medicine, studies have shown a higher ratio of female representation in the program director position compared with division chief in multiple specialties. This study aims (to determine) whether (this trend exists in) 3(-year) g(astroenterology fellowships in the U)nited States and to evaluate for any factors that may affect these differences. METHODS: In 2015, data were collected for the 163 U...
January 30, 2017: Gastrointestinal Endoscopy
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