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Gastrointestinal Endoscopy

A J de Groof, A Swager, R E Pouw, B L A M Weusten, E J Schoon, R Bisschops, O Pech, A Meining, H Neuhaus, W L Curvers, J J Bergman
BACKGROUND AND AIMS: Endoscopic features of early neoplasia in Barrett's esophagus (BE) are subtle. Blue-light imaging (BLI) may improve visualization of neoplastic lesions. The aim of this study was to evaluate BLI in visualization of Barrett's neoplasia. METHODS: Corresponding whit- light endoscopy (WLE) and BLI images of 40 BE lesions were obtained prospectively and assessed by 6 international experts in 3 assessments. Each assessment consisted of overview and magnification images...
November 9, 2018: Gastrointestinal Endoscopy
Ka Young Lee, Hyun Deuk Cho, Young Hwangbo, Jae Kook Yang, Su Jung Han, Hyun Jong Choi, Yun Nah Lee, Sang-Woo Cha, Jong Ho Moon, Young Deok Cho, Sang-Heum Park, Tae Hoon Lee
BACKGROUND AND AIMS: EUS-guided fine-needle aspiration/biopsy (EUS-FNA/B) has a high diagnostic accuracy for pancreatic tumors. Most reports have focused on the diagnostic yield of cytology or histology; the ability of various FNA/B techniques to obtain an adequate mass of cells or tissue has rarely been investigated. METHODS: Patients with suspected pancreatic malignancy were sampled by EUS-FNB using a 22-gauge ProCore needle by either the stylet slow-pull-back technique (group A), conventional negative-suction after stylet removal (group B) or non-suction after stylet removal (group C) in the absence of on-site cytopathologist...
November 4, 2018: Gastrointestinal Endoscopy
Hyo-Joon Yang, Chang Woo Cho, Sang Soo Kim, Kwang-Sung Ahn, Soo-Kyung Park, Dong Il Park
BACKGROUND AND AIMS: We aimed to develop deep learning models for the prediction of the risk of advanced colorectal neoplasia (ACRN) in asymptomatic adults based on which colorectal cancer screening could be customized. METHODS: We collected data on 26 clinical and laboratory parameters including age, sex, smoking status, body mass index, complete blood count, blood chemistry, and tumor marker from 70,336 first-time screening colonoscopy recipients. For reference, we used a logistic regression (LR) model with nine variables...
November 4, 2018: Gastrointestinal Endoscopy
Shu-Ling Li, Li Zhao, Zi-Kai Wang, Wen Li
BACKGROUND AND AIMS: Natural orifice transluminal endoscopic surgery (NOTES) has been established in animal models and human studies, but few clinical studies have investigated transvaginal NOTES in the diagnosis of unexplained refractory ascites. We aimed to assess the feasibility, efficacy, and safety of transvaginal NOTES for the diagnosis of unexplained ascites in female patients. METHODS: A prospective study was done involving 3 female patients with unexplained ascites...
October 31, 2018: Gastrointestinal Endoscopy
Elyse R Johnston, Nadia Habib-Bein, Jeffrey M Dueker, Barbara Quiroz, Enrico Corsaro, Megan Ambrogio, Michael Kingsley, Georgios I Papachristou, Christianna Kreiss, Asif Khalid
BACKGROUND AND AIMS: Non-universal use of facial protection during endoscopy may place endoscopists at risk of exposure to blood and body fluids; however, the frequency of exposure is unknown. METHODS: A prospective 6-month study of 4 gastroenterologists using a face shield during endoscopy was undertaken. The face shield was swabbed in a standardized fashion before and at the end of the session. Controls included pre- and post-swabs of face shields placed on the (1) endoscopy suite wall, (2) remote patient intake bay wall, and (3) after deliberate contamination with a colonoscope immediately after colonoscopy...
October 31, 2018: Gastrointestinal Endoscopy
Babu P Mohan, Mohammed Shakhatreh, Rajat Garg, Suresh Ponnada, Douglas G Adler
BACKGROUND AND AIMS: EUS-guided liver biopsy (LB) is an emerging technique to conventional percutaneous (PC) or transjugular (TJ) approaches. Recent studies have reported that EUS-guided LB (EUS-LB) may have a better safety profile compared with PC-LB or TJ-LB without compromising diagnostic yield, and the outcomes are varied with respect to the types of biopsy needles. We performed a systematic review and meta-analysis to estimate the diagnostic yield, specimen adequacy, and adverse events associated with EUS-LB...
October 30, 2018: Gastrointestinal Endoscopy
Judith Honing, Wietske Kievit, Jan Bookelaar, Yonne Peters, Prasad G Iyer, Peter D Siersema
BACKGROUND AND AIMS: Barrett's esophagus (BE) screening is currently not considered to be cost effective in the general population but may be effective in high-risk subgroups, such as 50-year-old white men with chronic reflux disease (GERD). A new modality for screening is unsedated transnasal endoscopy using endosheath technology (uTNE), which has been shown to be safe and effective in clinical practice. In this study, we determined the cost-utility of uTNE in a high-risk subgroup compared with no screening or screening with standard endoscopy (SE)...
October 29, 2018: Gastrointestinal Endoscopy
Joseph C Anderson, Charles J Kahi, Andrew Sullivan, Margaret MacPhail, Jonathan Garcia, Douglas K Rex
BACKGROUND AND AIMS: Although water exchange may improve adenoma detection when compared to CO2 , it is unclear whether water is a better medium to fill the lumen during withdrawal and visualize the mucosa. Total underwater (TUC) involves the use of water exchange with the air valve off during insertion followed by the inspection of the mucosa under water. Our goal was to use a tandem colonoscopy design to compare miss rates for TUC to standard CO2 for polyps and adenomas. METHODS: We randomized participants (NCT03231917; clinicaltrials...
October 24, 2018: Gastrointestinal Endoscopy
Tsuyoshi Ozawa, Soichiro Ishihara, Mitsuhiro Fujishiro, Hiroaki Saito, Youichi Kumagai, Satoki Shichijo, Kazuharu Aoyama, Tomohiro Tada
BACKGROUND AND AIMS: Evaluation of endoscopic disease activity for patients with ulcerative colitis (UC) is important when determining the treatment of choice. However, endoscopists require a certain period of training to evaluate the activity of inflammation properly, and interobserver variability exists. Therefore, we constructed a computer-assisted diagnosis (CAD) system using a convolutional neural network (CNN) and evaluated its performance using a large data set of endoscopic images from patients with UC...
October 24, 2018: Gastrointestinal Endoscopy
Priscilla A van Riet, Alberto Larghi, Fabia Attili, Guido Rindi, Nam Quoc Nguyen, Andrew Ruszkiewicz, Masayuki Kitano, Takaaki Chikugo, Harry Aslanian, James Farrell, Marie Robert, Adebowale Adeniran, Schalk van der Merwe, Tania Roskams, Kenneth Chang, Fritz Lin, John G Lee, Paolo Giorgio Arcidiacono, Mariachiara Petrone, Claudio Doglioni, Julio Iglesias-Garcia, Ihab Abdulkader, Marc Giovannini, Erwan Bories, Flora Poizat, Erwin Santo, Erez Scapa, Silvia Marmor, Juan Carlos Bucobo, Jonathan M Buscaglia, Alan Heimann, Maoxin Wu, Francisco Baldaque-Silva, Carlos Fernández Moro, Nicole S Erler, Katharina Biermann, Jan Werner Poley, Djuna L Cahen, Marco J Bruno
BACKGROUND AND AIMS: Several studies have compared EUS fine-needle aspiration (FNA) with biopsy (FNB) needles, but none has proven superiority. We performed a multicenter randomized controlled trial to compare the performance of a commonly used 25-gauge FNA needle with a newly designed 20-gauge FNB needle. METHODS: Consecutive patients with a solid lesion were randomized in this international multicenter study between a 25-gauge FNA (EchoTip Ultra) or a 20-gauge FNB needle (ProCore)...
October 24, 2018: Gastrointestinal Endoscopy
Bo Shen, Gursimran Kochhar, Udayakumar Navaneethan, Xiuli Liu, Francis A Farraye, Yago Gonzalez Lama, David Bruining, Darrell S Pardi, Martin Lukas, Martin Bortlik, Kaicun Wu, Ajit Sood, David A Schwartz, William J Sandborn
Interventional (or therapeutic) inflammatory bowel disease (IBD) endoscopy has an expanding role in the treatment of disease and surgical adverse events. Endoscopic therapy has been explored and used in the management of strictures, fistulas/abscesses, colitis-associated neoplasia, post-surgical acute or chronic leaks, and obstructions. The endoscopic therapeutic modalities include balloon dilation, stricturotomy, stent placement, fistulotomy, fistula injection and clipping, sinusotomy, endoscopic mucosal resection, and endoscopic submucosal dissection...
October 23, 2018: Gastrointestinal Endoscopy
Cesare Hassan, Carlo Senore, Gianpiero Manes, Lorenzo Fuccio, Federico Iacopini, Luigi Ricciardiello, Andrea Anderloni, Leonardo Frazzoni, Riccardo Ballanti, Germana de Nucci, Dora Colussi, Davide Radaelli, Roberto Lorenzetti, Massimo Devani, Ilaria Arena, Cristina Grossi, Fabio Andrei, Eleonora Balestrazzi, Prateek Sharma, Doug K Rex, Alessandro Repici
BACKGROUND AND AIMS: The add-on EndoRings has been claimed to improve adenoma detection at colonoscopy, but available data are inconsistent. When testing a new technology, parallel and crossover methodologies measure different outcomes, leaving uncertainty on their correspondence. Aims of this study were to compare the diagnostic yield and miss rate of the EndoRings for colorectal neoplasia. METHODS: Consecutive subjects undergoing colonoscopy after a positive fecal immunochemical test (FIT) within organized screening program in 7 Italian centers, were randomized between a parallel (EndoRings or Standard) or a crossover (EndoRings/Standard or Standard/EndoRings) methodology...
October 23, 2018: Gastrointestinal Endoscopy
Yuko Sakakibara, Shoichi Nakazuru, Tomofumi Akasaka, Hisashi Ishida, Eiji Mita
No abstract text is available yet for this article.
October 22, 2018: Gastrointestinal Endoscopy
Alex M Kesler, Omar Y Mousa, Beau Toskich, Gregory Frey, Michele Lewis
No abstract text is available yet for this article.
October 22, 2018: Gastrointestinal Endoscopy
Behnam Moein Jahromi, Franklin Tsai
No abstract text is available yet for this article.
October 22, 2018: Gastrointestinal Endoscopy
Peter Klare, Christoph Sander, Martin Prinzen, Bernhard Haller, Sebastian Nowack, Mohamed Abdelhafez, Alexander Poszler, Hayley Brown, Dirk Wilhelm, Roland M Schmid, Stefan von Delius, Thomas Wittenberg
BACKGROUND AND AIMS: Adenoma detection is a highly personalized task that differs markedly between endoscopists. Technical advances are therefore desirable for the improvement of the adenoma detection rate (ADR). An automated computer driven technology would offer the chance to objectively assess the presence of colorectal polyps during colonoscopy. We present here the application of a real-time automatic polyp detection software (APDS) under routine colonoscopy conditions. METHODS: This was a prospective study at a university hospital in Germany...
October 17, 2018: Gastrointestinal Endoscopy
Madhav Desai, David A Lieberman, Kevin F Kennedy, Nour Hamade, Prashanthi Thota, Sravanthi Parasa, Venkat Subhash Gorrepati, Ajay Bansal, Neil Gupta, Srinivas Gaddam, Patrick E Young, Sharad Mathur, Fouad J Moawad, Brooks D Cash, Richard Sampliner, John J Vargo, Gary W Falk, Prateek Sharma
INTRODUCTION: Data on time trends of dysplasia and esophageal adenocarcinoma (EAC) in Barrett's esophagus (BE) during the index endoscopy (ie, prevalent cases) are limited. Our aim was to determine the prevalence patterns of BE associated dysplasia on index endoscopy over the past 25 years. METHODS: The Barrett's esophagus study is a multicenter outcome project of a large cohort of BE patients. Proportion of patients with index endoscopy findings of no dysplasia (NDBE), low-grade dysplasia (LGD), high-grade dysplasia (HGD), and esophageal adenocarcinoma (EAC) were extracted per year of index endoscopy, and 5-yearly patient cohorts were tabulated over years 1990 to 2010+ (2010-current)...
October 17, 2018: Gastrointestinal Endoscopy
Maoyin Pang, Andree Koop, Bhaumik Brahmbhatt, Michael J Bartel, Timothy A Woodward
BACKGROUND AND AIMS: Incision of the cricopharyngeal (CP) muscle with flexible endoscopy is an important approach for Zenker diverticulum (ZD) repair with symptomatic resolution in approximately 90% of cases, but recurrence has been reported in up to 20%. We report our experience with a new endoscopic myectomy of the CP muscle and compare the outcome with conventional myotomy of ZD. METHODS: Our retrospective study included all patients with ZD who underwent endoscopic repair between August 1, 2014, and July 31, 2017...
October 17, 2018: Gastrointestinal Endoscopy
Bilal Toka, Ahmet Tarik Eminler, Cengiz Karacaer, Mustafa Ihsan Uslan, Aydin Seref Koksal, Erkan Parlak
BACKGROUND AND AIMS: Although various methods are used in the treatment of peptic ulcer bleeding, there is not a standard recommended approach. The choice depends on multiple factors such as location of the ulcer, clinical experience of endoscopist and local facilities of the clinic. We aimed to compare the efficacy of monopolar hemostatic forceps soft coagulation (MHFSC) and hemoclips (HC) in the treatment of peptic ulcer related upper GI bleeding. PATIENTS AND METHODS: The study group included patients who had GI bleeding due to Forrest 1a, 1b, 2a gastric or duodenal ulcers within 1 year...
October 17, 2018: Gastrointestinal Endoscopy
Tamika S Jaswani, Alexander J Williams, Douglas J Grider, Paul Yeaton, Mohammad H Shakhatreh
No abstract text is available yet for this article.
October 17, 2018: Gastrointestinal Endoscopy
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