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Fertility and Sterility

Innie Chen, Shifana Lalani, Ri-Hua Xie, Minxue Shen, Sukhbir S Singh, Shi-Wu Wen
OBJECTIVE: To examine the association between surgically diagnosed endometriosis and pregnancy outcomes in subsequent pregnancies. DESIGN: Retrospective cohort study of women who delivered a singleton live birth from 2003 to 2013 in Ottawa, Ontario, Canada. SETTING: Tertiary level academic center. PATIENT(S): Pregnant women with surgically diagnosed endometriosis were identified using International Classification of Diseases-10 codes from previous hospital admissions and were compared with pregnant women with no prior admission for endometriosis for the occurrences of adverse pregnancy outcomes...
November 29, 2017: Fertility and Sterility
Moran Shapira, Hila Raanani, Iris Barshack, Ninette Amariglio, Sanaz Derech-Haim, Meital Nagar Marciano, Eyal Schiff, Raoul Orvieto, Dror Meirow
OBJECTIVE: To describe a successful autologous ovarian tissue re-transplantation in a sterile leukemia survivor after evaluation for minimal residual disease and provide a review of the current literature. DESIGN: Presentation of a carefully designed workup taken to evaluate tissue for minimal residual disease, its limitations, and applicability to other patients. To date, there have not been any publications of auto-transplantations in leukemia survivors, owing to an estimated high risk for malignancy induction...
November 29, 2017: Fertility and Sterility
Aysen Boza, Sule Yildiz Oguz, Selim Misirlioglu, Kayhan Yakin, Bulent Urman
OBJECTIVE: To study the use of the Bologna criteria (BC) for the definition of poor ovarian responders (POR) in clinical practice and research. DESIGN: Systematic review of published and unpublished/ongoing trials between January 2012 and August 2017 on POR. SETTING: Not applicable. PATIENT(S): Not applicable. INTERVENTION(S): The databases were searched using the relevant medical subject headings including all subheadings...
November 29, 2017: Fertility and Sterility
Francesca Spinella, Francesco Fiorentino, Anil Biricik, Sara Bono, Alessandra Ruberti, Ettore Cotroneo, Marina Baldi, Elisabetta Cursio, Maria Giulia Minasi, Ermanno Greco
OBJECTIVE: To assess whether the extent of chromosomal mosaicism can influence the success rate of IVF treatments. DESIGN: Prospective study. SETTING: Private genetic and assisted reproduction centers. PATIENT(S): The transfer of mosaic embryos was offered to 77 women for which IVF resulted in no euploid embryos available for transfer. INTERVENTION(S): All embryos were cultured to blastocyst stage; trophectoderm biopsy was performed on day 5/6 of development...
November 28, 2017: Fertility and Sterility
Kristy Cho, Caitlin Dunne, Arianne Y K Albert, Jon C Havelock
OBJECTIVE(S): To determine whether an association exists between small crown-rump length (CRL) and adverse obstetrical outcomes in pregnancies conceived by IVF and to compare a CRL reference based on IVF pregnancies to a reference based on spontaneous pregnancies. DESIGN: Retrospective cohort study. CRL was classified as small by comparing it with the local university hospital maternal fetal medicine standard and the Monash IVF reference chart. SETTING: University-affiliated fertility center...
November 28, 2017: Fertility and Sterility
Zeev Blumenfeld
No abstract text is available yet for this article.
November 23, 2017: Fertility and Sterility
Alice D Domar
No abstract text is available yet for this article.
November 23, 2017: Fertility and Sterility
Amerigo Vitagliano, Marco Noventa, Gabriele Saccone, Salvatore Gizzo, Salvatore Giovannni Vitale, Antonio Simone Laganà, Pietro Salvatore Litta, Carlo Saccardi, Giovanni Battista Nardelli, Attilio Di Spiezio Sardo
OBJECTIVE: To assess the impact of endometrial scratch injury (ESI) on the outcomes of intrauterine insemination (IUI) stimulated cycles. DESIGN: Systematic review and meta-analysis. SETTING: Not applicable. PATIENT(S): Infertile women undergoing one or more IUI stimulated cycles. INTERVENTION(S): Randomized controlled trials (RCTs) were identified by searching electronic databases. We included RCTs comparing ESI (i...
November 23, 2017: Fertility and Sterility
Mette Toftager, Randi Sylvest, Lone Schmidt, Jeanette Bogstad, Kristine Løssl, Lisbeth Prætorius, Anne Zedeler, Thue Bryndorf, Anja Pinborg
OBJECTIVE: To compare self-reported quality of life, psychosocial well-being, and physical well-being during assisted reproductive technology (ART) treatment in 1,023 women allocated to either a short GnRH antagonist or long GnRH agonist protocol. DESIGN: Secondary outcome of a prospective phase 4, open-label, randomized controlled trial. Four times during treatment a questionnaire on self-reported physical well-being was completed. Further, a questionnaire on self-reported quality of life and psychosocial well-being was completed at the day of hCG testing...
November 23, 2017: Fertility and Sterility
Julie Barberet, Jérémy Chammas, Céline Bruno, Elodie Valot, Clarisse Vuillemin, Lysiane Jonval, Cécile Choux, Paul Sagot, Agnès Soudry, Patricia Fauque
OBJECTIVE: To study whether the closed culture system, as compared with a benchtop incubator with similar culture conditions, has a positive impact on intracytoplasmic sperm injection (ICSI) outcomes. DESIGN: Randomized controlled trial. SETTING: University hospital. PATIENT(S): A total of 386 patients undergoing ICSI cycles with at least six mature oocytes were randomized. INTERVENTION(S): Of these patients, 195 were assigned to the group with culture in a time-lapse imaging (TLI) system (EmbryoScope) and 191 to the group with culture in the G185 K-System (G185)...
November 23, 2017: Fertility and Sterility
Jun Gao, Fang Gu, Ben-Yu Miao, Ming-Hui Chen, Can-Quan Zhou, Yan-Wen Xu
OBJECTIVE: To analyze the influence of the start point of luteal support on clinical pregnancy rate, implantation rate, and live birth rate of in vitro fertilization and embryo transfer (IVF-ET) cycles. DESIGN: Single-center prospective randomized controlled trial. SETTING: University-affiliated IVF unit. PATIENT(S): Women ≤35 years of age with day 3 FSH levels <15 mIU/mL, who were undergoing their first IVF-ET cycles and received ovarian stimulation with the use of a GnRH agonist long protocol...
November 23, 2017: Fertility and Sterility
Joshua D Kapfhamer, Sruthi Palaniappan, Karen Summers, Kristen Kassel, Abigail C Mancuso, Ginny L Ryan, Divya K Shah
OBJECTIVE: To investigate whether the difference between mean gestational sac diameter and crown-rump length (mGSD - CRL) is associated with first-trimester pregnancy loss or adverse pregnancy outcomes after in vitro fertilization (IVF) and to determine if mGSD - CRL is a better predictor of pregnancy loss than either measurement alone. DESIGN: Retrospective cohort study. SETTING: University hospital. PATIENT(S): A total of 1,243 IVF cycles with fresh or cryopreserved autologous embryo transfers resulting in singleton gestations performed at the University of Iowa Hospitals and Clinics from January 2005 through December 2014...
November 23, 2017: Fertility and Sterility
Fangyin Meng, Gregory Zapantis, Samuel Z Williams, Harry J Lieman, Erkan Buyuk, U Thomas Meier
OBJECTIVE: To assess whether nucleolar channel systems (NCSs) can be detected in exfoliated endometrial epithelial cells (EECs) of uterine secretions and whether such noninvasively determined NCS status is associated with significant NCS prevalence in simultaneously obtained endometrial biopsies. DESIGN: Prospective study (December 2015-February 2017). SETTING: University-affiliated and private fertility clinics. PATIENT(S): Luteal-phase patients of reproductive age requiring endometrial biopsy for medical indications...
November 23, 2017: Fertility and Sterility
Hongli Liu, Xiaofei Xu, Ting Han, Lei Yan, Lei Cheng, Yingying Qin, Wen Liu, Shidou Zhao, Zi-Jiang Chen
OBJECTIVE: To identify the potential FSHR mutation in a Chinese woman with primary ovarian insufficiency (POI). DESIGN: Genetic and functional studies. SETTING: University-based reproductive medicine center. PATIENT(S): A POI patient, her family members, and another 192 control women with regular menstruation. INTERVENTION(S): Ovarian biopsy was performed in the patient. Sanger sequencing was carried out for the patient, her sister, and parents...
November 18, 2017: Fertility and Sterility
Russell P Hayden, James A Kashanian
No abstract text is available yet for this article.
November 17, 2017: Fertility and Sterility
Sandie Ha, Rajeshwari Sundaram, Germaine M Buck Louis, Carrie Nobles, Indulaxmi Seeni, Seth Sherman, Pauline Mendola
OBJECTIVE: To estimate the association of pregnancy loss with common air pollutant exposure. Ambient air pollution exposure has been linked to adverse pregnancy outcomes, but few studies have investigated its relationship with pregnancy loss. DESIGN: Prospective cohort study. SETTING: Not applicable. PATIENT(S): A total of 343 singleton pregnancies in a multisite prospective cohort study with detailed protocols for ovulation and pregnancy testing...
November 14, 2017: Fertility and Sterility
Jan Baekelandt
OBJECTIVE: To demonstrate a new approach for performing a myomectomy via transvaginal natural-orifice transluminal endoscopic surgery (vNOTES) as an alternative to laparoscopic myomectomy. DESIGN: Stepwise explanation of the technique with the use of original video footage. SETTING: Hospital. PATIENT(S): Eight patients were treated transvaginally for intramural, subserosal, and pedunculated myomas. INTERVENTION(S): In case of a posterior myoma, a 2...
November 9, 2017: Fertility and Sterility
Ricardo F Savaris
No abstract text is available yet for this article.
November 9, 2017: Fertility and Sterility
Laura D Almquist, Creighton E Likes, Benjamin Stone, Kaitlin R Brown, Ricardo Savaris, David A Forstein, Paul B Miller, Bruce A Lessey
OBJECTIVE: To evaluate endometrial BCL6 expression as a prognostic biomarker for IVF outcome in women with unexplained infertility (UI) before ET. DESIGN: Prospective cohort study. SETTING: University-associated infertility clinic. PATIENT(S): Women with UI for >1 year. INTERVENTION(S): We studied women with UI who underwent testing for endometrial BCL6, in an LH-timed midluteal phase biopsy and completed an IVF cycle and ET...
November 7, 2017: Fertility and Sterility
Cara K Bradley, Mark Livingstone, Maria V Traversa, Steven J McArthur
OBJECTIVE: To assess the impact of multiple blastocyst biopsy and vitrification-warming procedures on clinical outcomes. DESIGN: Retrospective study. SETTING: Private fertility clinic. PATIENT(S): Preimplantation genetic diagnosis (PGD) patients undergoing comprehensive chromosome screening, including monogenic disorder and chromosome rearrangement cases. INTERVENTION(S): Warming and transfer of euploid blastocysts biopsied and vitrified-warmed once (group 1 [G1, control]; n = 2,130), biopsied once but vitrified-warmed twice (group 2 [G2]; n = 34), or biopsied and vitrified-warmed twice (group 3 [G3]; n = 29)...
October 31, 2017: Fertility and Sterility
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