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Fertility and Sterility

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https://www.readbyqxmd.com/read/27919441/male-reproductive-health-training-during-undergraduate-medical-education-an-unmet-need-for-the-next-generation
#1
EDITORIAL
Esther Finney, Robert E Brannigan
No abstract text is available yet for this article.
December 2, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27919440/partnered-sexual-activity-moderates-menstrual-cycle-related-changes-in-inflammation-markers-in-healthy-women-an-exploratory-observational-study
#2
Tierney K Lorenz, Gregory E Demas, Julia R Heiman
OBJECTIVE: To examine differences in inflammation markers in sexually active versus abstinent women and observe changes in inflammation markers across the menstrual cycle. Cycle-related immune fluctuations may have evolved to reduce interference with conception. If so, reproductively active (i.e., sexually active) women should show the most variability in cytokine expression. DESIGN: Participants provided serum samples at menses and ovulation (from which cytokines were assayed) and saliva samples at menses and during follicular, ovulation, and luteal phases (from which C-reactive protein [CRP] was assayed)...
December 2, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27919439/associations-between-physical-activity-and-semen-quality-in-young-healthy-men
#3
Paweł Jóźków, Marek Mędraś, Felicja Lwow, Aleksandra Zagrodna, Małgorzata Słowińska-Lisowska
OBJECTIVE: To evaluate whether the level of everyday physical activity is associated with semen quality in young men. DESIGN: Cross-sectional study. SETTING: Universities, clubs, and societies. PATIENT(S): Young healthy men (aged 18-35 years) with unknown fertility (n = 177). INTERVENTIONS(S): Collection of data on medical history, lifestyle factors (physical activity, nutrition, addictions), and environmental threats (exposure of gonads to cellular phones, laptops)...
December 2, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27919438/does-an-increased-body-mass-index-affect-endometrial-gene-expression-patterns-in-infertile-patients-a%C3%A2-functional-genomics-analysis
#4
Ioanna A Comstock, Patricia Diaz-Gimeno, Sergio Cabanillas, Jose Bellver, Patricia Sebastian-Leon, Meera Shah, Amy Schutt, Cecilia T Valdes, Maria Ruiz-Alonso, Diana Valbuena, Carlos Simon, Ruth B Lathi
OBJECTIVE: To analyze the transcriptomic profile of endometrial gene alterations during the window of implantation in infertile obese patients. DESIGN: Multicenter, prospective, case-control study. SETTING: Three academic medical centers for reproductive medicine. PATIENT(S): Infertile patients, stratified into body mass index (BMI) categories according to the World Health Organization guidelines, were included in the study...
December 2, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27919437/fertile-lifespan-characteristics-and-all-cause-and-cause-specific-mortality-among-postmenopausal-women-the-rotterdam-study
#5
Loes Jaspers, Maryam Kavousi, Nicole S Erler, Albert Hofman, Joop S E Laven, Oscar H Franco
OBJECTIVE: To characterize the relation between established and previously unexplored characteristics of the fertile life with all-cause and cause-specific mortality. DESIGN: Prospective cohort study. SETTING: Not applicable. PATIENT(S): A total of 4,076 postmenopausal women. INTERVENTION(S): Women's fertile lifespan (age at menarche to menopause), number of children, maternal age at first and last child, maternal lifespan (interval between maternal age at first and last child), postmaternal fertile lifespan (interval between age at last child and menopause), lifetime cumulative number of menstrual cycles, and unopposed cumulative endogenous estrogen (E) exposure...
December 2, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27916207/integrating-insulin-into-single-step-culture-medium-regulates-human-embryo-development-in%C3%A2-vitro
#6
Mohamed Fawzy, Mohamed Sabry, Mohamed Nour, Mohamed Y Abdelrahman, Eman Roshdy, Yasmin Magdi, Hazem Abdelghafar
OBJECTIVE: To evaluate the effect of supplementing single-step embryo culture medium with insulin on human embryo development. DESIGN: Comparative study. SETTING: Two private centers. PATIENT(S): The study involved a sibling oocyte split of 5,142 retrieved oocytes from 360 patients. INTERVENTION(S): Sibling oocytes split after intracytoplasmic sperm injection for culture from day 0 through day 5 or 6 in insulin-supplemented or control medium...
December 1, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27916206/how-many-oocytes-are-optimal-to%C3%A2-achieve-multiple-live-births-with%C3%A2-one-stimulation-cycle-the%C3%A2-one%C3%A2-and-done-approach
#7
Denis A Vaughan, Angela Leung, Nina Resetkova, Robin Ruthazer, Alan S Penzias, Denny Sakkas, Michael M Alper
OBJECTIVE: To study how many infertility patients would complete an average-sized family (achieve ≥2 live births) after a single, complete in vitro fertilization (IVF) cycle. DESIGN: A retrospective cohort study. SETTING: University-affiliated private infertility practice. PATIENT(S): Women undergoing IVF. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): The outcome of 1 or ≥2 live births after a single retrieval cycle, followed by use of all embryos in subsequent frozen cycles in relation to oocyte number...
December 1, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27916205/efficacy-and-safety-of-transdermal-testosterone-in-postmenopausal-women-with-hypoactive-sexual-desire-disorder-a-systematic-review-and-meta-analysis
#8
Chiara Achilli, Jyotsna Pundir, Parimalam Ramanathan, Luca Sabatini, Haitham Hamoda, Nick Panay
OBJECTIVE: To systematically review and summarize the existing evidence related to the efficacy and safety of transdermal T in postmenopausal women for the treatment of hypoactive sexual desire disorder (HSDD). DESIGN: Systematic reviews and meta-analysis. SETTING: Not applicable. PATIENT(S): Seven randomized controlled trials enrolled 3,035 participants; 1,350 women were randomized to treatment with T patch, and 1,379 women were randomized to placebo...
December 1, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27889101/highly-heterogeneous-genomic-landscape-of-uterine-leiomyomas-by%C3%A2-whole-exome-sequencing-and-genome-wide-arrays
#9
Svetlana A Yatsenko, Priya Mittal, Michelle A Wood-Trageser, Mirka W Jones, Urvashi Surti, Robert P Edwards, Anil K Sood, Aleksandar Rajkovic
OBJECTIVE: To determine the genomic signatures of human uterine leiomyomas and prevalence of MED12 mutations in human uterine leiomyosarcomas. DESIGN: Retrospective cohort study. SETTING: Not applicable. PATIENT(S): This study included a set of 16 fresh frozen leiomyoma and corresponding unaffected myometrium specimens as well as 153 leiomyosarcomas collected from women diagnosed with uterine leiomyomas or leiomyosarcomas who underwent clinically indicated abdominal hysterectomy...
November 23, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27889100/epigenetic-regulation-of-an-adverse-metabolic-phenotype-in-polycystic-ovary-syndrome-the-impact-of-the-leukocyte-methylation-of-ppargc1a-promoter
#10
Hongcui Zhao, Yue Zhao, Yun Ren, Min Li, Tianjie Li, Rong Li, Yang Yu, Jie Qiao
OBJECTIVE: To investigate PPARGC1A promoter methylation and mitochondria DNA (mtDNA) content in the leukocytes of women with polycystic ovary syndrome (PCOS) and analyze the relationship between these indices and metabolic risk for women with PCOS. DESIGN: Cross-sectional study. SETTING: University hospital. PATIENT(S): A total of 175 women with PCOS and 127 healthy controls. INTERVENTION(S): None...
November 23, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27889099/eating-disorders-in-the-context-of-preconception-care-fertility-specialists-knowledge-attitudes-and-clinical-practices
#11
Iolanda S Rodino, Susan M Byrne, Katherine A Sanders
OBJECTIVE(S): To gauge fertility specialists' knowledge, clinical practices, and training needs in regard to eating disorders. DESIGN: Cross-sectional study. SETTINGS: Fertility clinics. PARTICIPANTS: Eighty Australian and New Zealand fertility specialists who were members of the Fertility Society of Australia. INTERVENTION(S): None. MAIN OUTCOME MEASURES(S): Responses to an anonymously completed online questionnaire...
November 23, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27912901/individualized-versus-conventional-ovarian-stimulation-for-in%C3%A2-vitro-fertilization-a-multicenter-randomized-controlled-assessor-blinded-phase-3-noninferiority-trial
#12
Anders Nyboe Andersen, Scott M Nelson, Bart C J M Fauser, Juan Antonio García-Velasco, Bjarke M Klein, Joan-Carles Arce
OBJECTIVE: To compare the efficacy and safety of follitropin delta, a new human recombinant FSH with individualized dosing based on serum antimüllerian hormone (AMH) and body weight, with conventional follitropin alfa dosing for ovarian stimulation in women undergoing IVF. DESIGN: Randomized, multicenter, assessor-blinded, noninferiority trial (ESTHER-1). SETTING: Reproductive medicine clinics. PATIENT(S): A total of 1,329 women (aged 18-40 years)...
November 22, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27887719/leucine-rich-repeat-containing-g-protein-coupled%C3%A2-receptor%C3%A2-5-positive%C3%A2-cells%C3%A2-in-the-endometrial-stem-cell-niche
#13
Irene Cervelló, Claudia Gil-Sanchis, Xavier Santamaría, Amparo Faus, Julia Vallvé-Juanico, Patricia Díaz-Gimeno, Oriana Genolet, Antonio Pellicer, Carlos Simón
OBJECTIVE: To study, isolate and characterize leucine-rich repeat-containing heterotrimeric guanine nucleotide-binding protein-coupled receptor 5 (LGR5)-positive cells from human endometrium to determine their functional relevance. DESIGN: Prospective experimental animal study. SETTING: University research laboratories. ANIMAL(S): Nonobese diabetic mice (NOD-SCID) (strain code 394; NOD.CB17-Prkdc(scid)/NcrCrl). INTERVENTION(S): Human LGR5(+) cells were labeled with superparamagnetic iron oxide nanoparticles (SPIOs) and injected under the kidney capsule in immunocompromised mice...
November 22, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27887718/novel-centrifugal-technology-for-measuring-sperm-concentration-in-the-home
#14
Ulrich Y Schaff, Laura L Fredriksen, Jon G Epperson, Tiffany R Quebral, Sara Naab, Mark J Sarno, Michael L Eisenberg, Greg J Sommer
OBJECTIVE: To evaluate the analytical performance and usability of the Trak Male Fertility Testing System, a semiquantitative (categorical) device recently US Food and Drug Administration (FDA)-cleared for measuring sperm concentration in the home by untrained users. DESIGN: A three-site clinical trial comparing self-reported lay user results versus reference results obtained by computer-aided semen analysis (CASA). SETTING: Simulated home use environments at fertility centers and urologist offices...
November 22, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27887717/the-continued-existence-of-significant-disparities-in-the-technical-practices-of-sperm-morphology-assessment-and-the-clinical-implications-results-of-a-french-questionnaire
#15
Nicolas Gatimel, Lucile Mansoux, Jessika Moreau, Jean Parinaud, Roger D Léandri
OBJECTIVE: To investigate current practices for sperm morphology assessment. DESIGN: E-mail survey questionnaire. SETTING: Diagnostic and clinical institutions/laboratories. PATIENT(S): French biologists and clinicians (n = 225). INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Answers to 24 questions. RESULT(S): The survey shows that even now in France there is great inconsistency in the use of sperm morphology assessments...
November 22, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27887716/who-requests-their-sperm-donor-s-identity-the-first-ten-years-of-information-releases-to-adults-with-open-identity-donors
#16
Joanna E Scheib, Alice Ruby, Jean Benward
OBJECTIVE: To report findings from 10 years of requests from adults eligible to obtain their open-identity sperm donor's information. DESIGN: Analysis of archived family and donor data. Semistructured interviews at information releases. SETTING: Not applicable. PATIENT(S): A total of 85 DI adults requesting 43 donor identities; program data on 256 DI families. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): We identified [1] demographic predictors of requesting donor identities, [2] information release timing and length, and [3] request motives...
November 22, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27887715/focus-on-recurrent-miscarriage-phenotypes
#17
EDITORIAL
David H Barad, Vitaly A Kushnir, Norbert Gleicher
No abstract text is available yet for this article.
November 22, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27887714/erratum
#18
(no author information available yet)
No abstract text is available yet for this article.
November 22, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27887713/magnetic-resonance-imaging-correlation-to-intraoperative-findings%C3%A2-of-deeply-infiltrative-endometriosis
#19
Traci E Ito, Elias D Abi Khalil, Myles Taffel, Gaby N Moawad
OBJECTIVE: To show characteristics of deeply infiltrative endometriosis (DIE) on magnetic resonance imaging (MRI) and how they correlate with intraoperative findings. DESIGN: Overview of still and dynamic MRI images of four different patients with DIE. We then used videos from their surgeries to highlight the appearance of endometriosis corresponding to these images (educational video). SETTING: University hospital. PATIENT(S): Four different patients with DIE were included in this video...
November 22, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27887712/thank-you-to-our-reviewers
#20
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
November 22, 2016: Fertility and Sterility
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