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European Urology

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https://www.readbyqxmd.com/read/28935163/optimising-the-diagnosis-of-prostate-cancer-in-the-era-of-multiparametric-magnetic-resonance-imaging-a-cost-effectiveness-analysis-based-on-the-prostate-mr-imaging-study-promis
#1
Rita Faria, Marta O Soares, Eldon Spackman, Hashim U Ahmed, Louise C Brown, Richard Kaplan, Mark Emberton, Mark J Sculpher
BACKGROUND: The current recommendation of using transrectal ultrasound-guided biopsy (TRUSB) to diagnose prostate cancer misses clinically significant (CS) cancers. More sensitive biopsies (eg, template prostate mapping biopsy [TPMB]) are too resource intensive for routine use, and there is little evidence on multiparametric magnetic resonance imaging (MPMRI). OBJECTIVE: To identify the most effective and cost-effective way of using these tests to detect CS prostate cancer...
September 18, 2017: European Urology
https://www.readbyqxmd.com/read/28927584/longer-telomere-length-and-renal-cell-carcinoma
#2
EDITORIAL
Jozefina Casuscelli, A Ari Hakimi
No abstract text is available yet for this article.
September 16, 2017: European Urology
https://www.readbyqxmd.com/read/28927585/whole-genome-and-transcriptome-sequencing-of-prostate-cancer-identify-new-genetic-alterations-driving-disease-progression
#3
Shancheng Ren, Gong-Hong Wei, Dongbing Liu, Liguo Wang, Yong Hou, Shida Zhu, Lihua Peng, Qin Zhang, Yanbing Cheng, Hong Su, Xiuqing Zhou, Jibin Zhang, Fuqiang Li, Hancheng Zheng, Zhikun Zhao, Changjun Yin, Zengquan He, Xin Gao, Haiyen E Zhau, Chia-Yi Chu, Jason Boyang Wu, Colin Collins, Stanislav V Volik, Robert Bell, Jiaoti Huang, Kui Wu, Danfeng Xu, Dingwei Ye, Yongwei Yu, Lianhui Zhu, Meng Qiao, Hang-Mao Lee, Yuehong Yang, Yasheng Zhu, Xiaolei Shi, Rui Chen, Yang Wang, Weidong Xu, Yanqiong Cheng, Chuanliang Xu, Xu Gao, Tie Zhou, Bo Yang, Jianguo Hou, Li Liu, Zhensheng Zhang, Yao Zhu, Chao Qin, Pengfei Shao, Jun Pang, Leland W K Chung, Jianfeng Xu, Chin-Lee Wu, Weide Zhong, Xun Xu, Yingrui Li, Xiuqing Zhang, Jian Wang, Huanming Yang, Jun Wang, Haojie Huang, Yinghao Sun
BACKGROUND: Global disparities in prostate cancer (PCa) incidence highlight the urgent need to identify genomic abnormalities in prostate tumors in different ethnic populations including Asian men. OBJECTIVE: To systematically explore the genomic complexity and define disease-driven genetic alterations in PCa. DESIGN, SETTING, AND PARTICIPANTS: The study sequenced whole-genome and transcriptome of tumor-benign paired tissues from 65 treatment-naive Chinese PCa patients...
September 15, 2017: European Urology
https://www.readbyqxmd.com/read/28917596/response-rate-to-chemotherapy-after-immune-checkpoint-inhibition-in-metastatic-urothelial-cancer
#4
Bernadett Szabados, Nick van Dijk, Yen Zhi Tang, Michiel van der Heijden, Akhila Wimalasingham, Alfonso Gomez de Liano, Simon Chowdhury, Simon Hughes, Sarah Rudman, Mark Linch, Thomas Powles
Immune checkpoint inhibitors (ICIs) are active in metastatic urothelial carcinoma (MUC). They have joined chemotherapy (CT) as a standard of care. Here, we investigate the activity of CT after progression on ICIs. Two cohorts of sequential patients with MUC were described (n=28). Cohort A received first-line ICIs followed by CT after progression. Cohort B received CT after failure of first-line platinum-based CT followed by ICIs. Response rate (RR) to CT was assessed using Response Evaluation Criteria in Solid Tumors (RECIST v1...
September 13, 2017: European Urology
https://www.readbyqxmd.com/read/28917595/perioperative-and-oncologic-outcomes-of-nephrectomy-and-caval-thrombectomy-using-extracorporeal-circulation-and-deep-hypothermic-circulatory-arrest-for-renal-cell-carcinoma-invading-the-supradiaphragmatic-inferior-vena-cava-and-or-right-atrium
#5
Alessandro Nini, Umberto Capitanio, Alessandro Larcher, Paolo Dell'Oglio, Federico Dehò, Nazareno Suardi, Fabio Muttin, Cristina Carenzi, Massimo Freschi, Roberta Lucianò, Giovanni La Croce, Alberto Briganti, Renzo Colombo, Andrea Salonia, Alessandro Castiglioni, Patrizio Rigatti, Francesco Montorsi, Roberto Bertini
BACKGROUND: Radical nephrectomy (RN) and caval thrombectomy (CT) for renal cell carcinoma, with extracorporeal circulation (ECC) and deep hypothermic circulatory arrest (DHCA) is a challenging surgical approach. OBJECTIVE: To assess peri-operative and oncologic outcomes of renal cell carcinoma patients treated with RN and CT, using ECC and DHCA. DESIGN, SETTING, AND PARTICIPANTS: We retrospectively evaluated 46 patients who underwent RN and CT using ECC and DHCA...
September 13, 2017: European Urology
https://www.readbyqxmd.com/read/28917594/key-steps-in-conducting-systematic-reviews-for-underpinning-clinical-practice-guidelines-methodology-of-the-european-association-of-urology
#6
Thomas Knoll, Muhammad Imran Omar, Steven Maclennan, Virginia Hernández, Steven Canfield, Yuhong Yuan, Max Bruins, Lorenzo Marconi, Hein Van Poppel, James N'Dow, Richard Sylvester
CONTEXT: The findings of systematic reviews (SRs) and meta-analyses (MAs) are used for clinical decision making. The European Association of Urology has committed increasing resources into the development of high quality clinical guidelines based on such SRs and MAs. OBJECTIVE: In this paper, we have summarised the process of conducting SRs for underpinning clinical practice guidelines under the auspices of the European Association of Urology Guidelines Office. EVIDENCE ACQUISITION: The process involves explicit methods and the findings should be reproducible...
September 13, 2017: European Urology
https://www.readbyqxmd.com/read/28916409/re-cytoreductive-nephrectomy-for-renal-cell-carcinoma-with-venous-tumor-thrombus
#7
Vsevolod B Matveev, Maria I Volkova
No abstract text is available yet for this article.
September 12, 2017: European Urology
https://www.readbyqxmd.com/read/28916408/robot-assisted-kidney-transplantation-the-european-experience
#8
Alberto Breda, Angelo Territo, Luis Gausa, Volkan Tuğcu, Antonio Alcaraz, Mireia Musquera, Karel Decaestecker, Liesbeth Desender, Michael Stockle, Martin Janssen, Paolo Fornara, Nasreldin Mohammed, Giampaolo Siena, Sergio Serni, Luis Guirado, Carma Facundo, Nicolas Doumerc
BACKGROUND: Robot-assisted kidney transplantation (RAKT) has recently been introduced to reduce the morbidity of open kidney transplantation (KT). OBJECTIVE: To evaluate perioperative and early postoperative RAKT outcomes. DESIGN, SETTING AND PARTICIPANTS: This was a multicenter prospective observational study of 120 patients who underwent RAKT, predominantly with a living donor kidney, in eight European institutions between July 2015 and May 2017, with minimum follow-up of 1 mo...
September 12, 2017: European Urology
https://www.readbyqxmd.com/read/28911808/renal-transplantation-after-treatment-for-a-urological-cancer-who-and-when-does-evidence-help-for-a-challenge
#9
EDITORIAL
Javier Burgos-Revilla, Victoria Gomez-Dos-Santos
No abstract text is available yet for this article.
September 11, 2017: European Urology
https://www.readbyqxmd.com/read/28890251/risk-of-bleeding-versus-venous-thromboembolism-in-urological-surgery-finding-the-right-balance-is-not-always-easy
#10
EDITORIAL
Malte Rieken, Alexander Bachmann
No abstract text is available yet for this article.
September 7, 2017: European Urology
https://www.readbyqxmd.com/read/28890250/re-association-between-direct-to-consumer-advertising-and-testosterone-testing-and-initiation-in-the-united-states-2009-2013
#11
Joshua S Jue, Ranjith Ramasamy
No abstract text is available yet for this article.
September 7, 2017: European Urology
https://www.readbyqxmd.com/read/28890249/re-the-use-of-apnea-during-ureteroscopy
#12
Paul Meria
No abstract text is available yet for this article.
September 7, 2017: European Urology
https://www.readbyqxmd.com/read/28890248/innovative-therapies-to-overcome-resistance-to-enzalutamide-perspective-on-the-use-of-darolutamide
#13
EDITORIAL
Zoran Culig
No abstract text is available yet for this article.
September 7, 2017: European Urology
https://www.readbyqxmd.com/read/28890247/new-insights-into-adjuvant-renal-cell-carcinoma-treatment-with-vascular-endothelial-growth-factor-inhibitors-what-have-we-learned-so-far
#14
EDITORIAL
Bernard Escudier, Michael Staehler
Adjuvant treatment of renal cell carcinoma with vascular endothelial growth factor inhibitors is feasible and effective with careful patient selection and standard dosing levels.
September 7, 2017: European Urology
https://www.readbyqxmd.com/read/28890246/reply-to-alan-dal-pra-stephane-supiot-and-pirus-ghadjar-s-letter-to-the-editor-re-giorgio-gandaglia-stephen-a-boorjian-william-p-parker-et-al-impact-of-postoperative-radiotherapy-in-men-with-persistently-elevated-prostate-specific-antigen-after-radical-prostatectomy
#15
LETTER
https://www.readbyqxmd.com/read/28890245/efficacy-of-local-treatment-in-prostate-cancer-patients-with-clinically-pelvic-lymph-node-positive-disease-at-initial-diagnosis
#16
Thomas Seisen, Malte W Vetterlein, Patrick Karabon, Tarun Jindal, Akshay Sood, Luigi Nocera, Paul L Nguyen, Toni K Choueiri, Quoc-Dien Trinh, Mani Menon, Firas Abdollah
BACKGROUND: There is limited evidence supporting the use of local treatment (LT) for prostate cancer (PCa) patients with clinically pelvic lymph node-positive (cN1) disease. OBJECTIVE: To examine the efficacy of any form of LT±androgen deprivation therapy (ADT) in treating these individuals. DESIGN, SETTING, AND PARTICIPANTS: Using the National Cancer Database (2003-2011), we retrospectively identified 2967 individuals who received LT±ADT versus ADT alone for cN1 PCa...
September 7, 2017: European Urology
https://www.readbyqxmd.com/read/28890244/re-comprehensive-qualitative-assessment-of-urethral-stricture-disease-toward-the-development-of-a-patient-centered-outcome-measure
#17
Sean P Elliott
No abstract text is available yet for this article.
September 7, 2017: European Urology
https://www.readbyqxmd.com/read/28890243/re-giorgio-gandaglia-stephen-a-boorjian-william-p-parker-et-al-impact-of-postoperative-radiotherapy-in-men-with-persistently-elevated-prostate-specific-antigen-after-radical-prostatectomy-for-prostate-cancer-a-long-term-survival-analysis-eur-urol-in-press-http
#18
LETTER
https://www.readbyqxmd.com/read/28882327/erectile-function-and-oncologic-outcomes-following-open-retropubic-and-robot-assisted-radical-prostatectomy-results-from-the-laparoscopic-prostatectomy-robot-open-trial
#19
Prasanna Sooriakumaran, Giovanni Pini, Tommy Nyberg, Maryam Derogar, Stefan Carlsson, Johan Stranne, Anders Bjartell, Jonas Hugosson, Gunnar Steineck, Peter N Wiklund
BACKGROUND: Whether surgeons perform better utilising a robot-assisted laparoscopic technique compared with an open approach during prostate cancer surgery is debatable. OBJECTIVE: To report erectile function and early oncologic outcomes for both surgical modalities, stratified by prostate cancer risk grouping. DESIGN, SETTING, AND PARTICIPANTS: In a prospective nonrandomised trial, we recruited 2545 men with prostate cancer from seven open (n=753) and seven robot-assisted (n=1792) Swedish centres (2008-2011)...
September 4, 2017: European Urology
https://www.readbyqxmd.com/read/28867447/quality-improvement-efforts-in-radical-cystectomy-from-prehab-to-rehab
#20
EDITORIAL
Matthew Mossanen, Mark A Preston
No abstract text is available yet for this article.
August 31, 2017: European Urology
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