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European Urology

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https://www.readbyqxmd.com/read/29342412/reply-to-christian-seitz-s-letter-to-the-editor-re-zhangqun-ye-guohua-zeng-huan-yang-et-al-efficacy-and-safety-of-tamsulosin-in-medical-expulsive-therapy-for-distal-ureteral-stones-with-renal-colic-a-multicenter-randomized-double-blind-placebo-controlled-trial
#1
LETTER
https://www.readbyqxmd.com/read/29338978/non-risk-adapted-surveillance-for-stage-i-testicular-cancer-critical-review-and-summary
#2
REVIEW
Phillip Martin Pierorazio, Peter Albers, Peter C Black, Torgrim Tandstad, Axel Heidenreich, Nicola Nicolai, Craig Nichols
CONTEXT: Cancer-specific survival for men with clinical stage I testicular cancer (CSITC) is uniformly excellent. Non-risk-adapted active surveillance (NRAS) is a management strategy for CSITC to minimize overtreatment and avoid possible long-term side effects of adjuvant therapy. OBJECTIVE: To review the evidence regarding oncologic outcomes for men with CSITC undergoing NRAS and discuss ongoing controversies in the management of CSITC. EVIDENCE ACQUISITION: MEDLINE/PubMed, Embase, and the Cochrane Central Register of Controlled Trials were searched from January 1, 1987 through January 1, 2017...
January 12, 2018: European Urology
https://www.readbyqxmd.com/read/29336927/efficacy-and-safety-of-sacral-and-percutaneous-tibial-neuromodulation-in-non-neurogenic-lower-urinary-tract-dysfunction-and-chronic-pelvic-pain-a-systematic-review-of-the-literature
#3
REVIEW
Manuela Tutolo, Enrico Ammirati, John Heesakkers, Thomas M Kessler, Kenneth M Peters, Tina Rashid, Karl-Dietrich Sievert, Michele Spinelli, Giacomo Novara, Frank Van der Aa, Dirk De Ridder
CONTEXT: Neuromodulation is considered in patients with non-neurogenic lower urinary tract dysfunction (LUTD) not responsive to conservative treatment. OBJECTIVE: To systematically review the available studies on efficacy and safety of sacral neuromodulation (SNM) and percutaneous tibial nerve stimulation (PTNS) in non-neurogenic LUTDs not responsive to conservative treatments. EVIDENCE ACQUISITION: A literature research was conducted in PubMed/Medline and Scopus, restricted to articles in English, published between January 1998 and June 2017, with at least 20 patients and 6 mo of follow-up...
January 11, 2018: European Urology
https://www.readbyqxmd.com/read/29336926/changes-of-tumour-node-metastasis-staging-in-2017-concepts-and-evolutions-in-the-european-and-american-continents
#4
EDITORIAL
Eva Compérat
No abstract text is available yet for this article.
January 11, 2018: European Urology
https://www.readbyqxmd.com/read/29331216/chemoimmunotherapy-in-metastatic-urothelial-carcinoma
#5
EDITORIAL
Daniel M Geynisman, Phillip H Abbosh, Elizabeth R Plimack, Matthew Zibelman
No abstract text is available yet for this article.
January 10, 2018: European Urology
https://www.readbyqxmd.com/read/29331215/re-zhangqun-ye-guohua-zeng-huan-yang-et-al-efficacy-and-safety-of-tamsulosin-in-medical-expulsive-therapy-for-distal-ureteral-stones-with-renal-colic-a-multicenter-randomized-double-blind-placebo-controlled-trial-eur-urol-in-press-https-doi-org-10-1016-j-eururo
#6
LETTER
https://www.readbyqxmd.com/read/29331214/the-stockholm-3-model-for-prostate-cancer-detection-algorithm-update-biomarker-contribution-and-reflex-test-potential
#7
Peter Ström, Tobias Nordström, Henrik Grönberg, Martin Eklund
BACKGROUND: It has been shown that the Stockholm-3 model (S3M) outperforms prostate-specific antigen (PSA) as a screening tool for prostate cancer. OBJECTIVE: To update the S3M, to give a detailed account of the value of each predictor in the S3M, and to evaluate the S3M as a reflex test for men with PSA ≥3ng/ml. DESIGN, SETTING, AND PARTICIPANTS: During 2012-2015, the Stockholm-3 study evaluated the S3M relative to PSA as tests for Gleason score ≥7 prostate cancers among men aged 50-69 yr...
January 10, 2018: European Urology
https://www.readbyqxmd.com/read/29325693/updates-in-the-eighth-edition-of-the-tumor-node-metastasis-staging-classification-for-urologic-cancers
#8
REVIEW
Gladell P Paner, Walter M Stadler, Donna E Hansel, Rodolfo Montironi, Daniel W Lin, Mahul B Amin
The Tumor-Node-Metastasis (TNM) classification on cancer staging, jointly developed by the American Joint Commission on Cancer (AJCC) and the Union for International Cancer Control (UICC), has been updated to its 8th edition with two contemporaneous versions published by the AJCC and UICC. While the goal of the AJCC and UICC is to have identical TNM staging systems, differences exist between these two publications including in the staging of urologic cancers. Among several new facets in the AJCC staging manual, a select few of greater import include an expanded section on imaging, presentation of levels of evidence for significant changes, and endorsement of risk assessment models that pass the AJCC quality criteria such as in prostate cancer...
January 8, 2018: European Urology
https://www.readbyqxmd.com/read/29317081/hyperaccuracy-three-dimensional-reconstruction-is-able-to-maximize-the-efficacy-of-selective-clamping-during-robot-assisted-partial-nephrectomy-for-complex-renal-masses
#9
Francesco Porpiglia, Cristian Fiori, Enrico Checcucci, Daniele Amparore, Riccardo Bertolo
BACKGROUND: Available technologies could avoid global ischemia for the removal of a renal tumor. OBJECTIVE: To present hyperaccuracy three-dimensional (HA3D) reconstruction during robot-assisted partial nephrectomy (RAPN) and compare its efficacy in sponsoring successful selective clamping of renal arterial branches during RAPN. DESIGN, SETTING, AND PARTICIPANTS: Patients undergoing RAPN (January 2016-July 2017) for renal mass PADUA score ≥10 who underwent abdominal computed tomography scan with angiography...
January 6, 2018: European Urology
https://www.readbyqxmd.com/read/29307509/two-years-postradiotherapy-biopsies-lessons-from-mrc-rt01-trial
#10
Antoine Kass-Iliyya, Gordana Jovic, Claire Murphy, Cyril Fisher, Isabel Syndikus, Chakiath Jose, Christopher D Scrase, John D Graham, David Nicol, Matthew R Sydes, David Dearnaley
BACKGROUND: The importance of 2-yr postradiotherapy prostate biopsy status remains uncertain. OBJECTIVE: To assess the value of 2 year post treatment biopsies in a randomised trial of radiotherapy dose escalation. DESIGN, SETTING, AND PARTICIPANTS: Between 1998 and 2001, 843 men with localised prostate cancer were randomised to receive either control-64Gy or escalated-74Gy conformal radiotherapy (CFRT) in the MRC RT01 trial in combination with 3-6-mo neoadjuvant androgen deprivation therapy...
January 4, 2018: European Urology
https://www.readbyqxmd.com/read/29306515/multiparametric-magnetic-resonance-imaging-for-prostate-specific-antigen-recurrence-after-radical-prostatectomy-are-we-leaving-the-one-treatment-fits-all-approach-and-moving-towards-personalized-imaging-guided-treatment
#11
EDITORIAL
https://www.readbyqxmd.com/read/29306514/intermediate-endpoints-after-postprostatectomy-radiotherapy-5-year-distant-metastasis-to-predict-overall-survival
#12
William C Jackson, Krithika Suresh, Vasu Tumati, Steven G Allen, Robert T Dess, Simpa S Salami, Arvin George, Samuel D Kaffenberger, David C Miller, Jason W D Hearn, Shruti Jolly, Rohit Mehra, Brent K Hollenbeck, Ganesh S Palapattu, Matthew Schipper, Felix Y Feng, Todd M Morgan, Neil B Desai, Daniel E Spratt
BACKGROUND: Intermediate clinical endpoints (ICEs) prognostic for overall survival (OS) are needed for men receiving postprostatectomy radiation therapy (PORT) to improve clinical trial design. OBJECTIVE: To identify a potential ICE for men receiving PORT. DESIGN, SETTING, AND PARTICIPANTS: We performed an institutional review board-approved multi-institutional retrospective study of 566 men consecutively treated with PORT at tertiary care centers from 1986 to 2013...
January 3, 2018: European Urology
https://www.readbyqxmd.com/read/29306513/management-of-men-with-prostate-specific-antigen-failure-after-prostate-radiotherapy-the-case-against-early-androgen-deprivation
#13
EDITORIAL
Douglas Brand, Chris Parker
In men with prostate-specific antigen failure after radical radiotherapy, androgen deprivation therapy should be delayed until the site of recurrence is known to allow consideration of curative treatment options, to delay androgen deprivation therapy-related morbidity, and to enable earlier access to abiraterone and docetaxel.
January 3, 2018: European Urology
https://www.readbyqxmd.com/read/29306512/erratum-to-checkmate-025-randomized-phase-3-study-outcomes-by-key-baseline-factors-and-prior-therapy-for-nivolumab-versus-everolimus-in-advanced-renal-cell-carcinoma-eur-urol-2017-72-962-71
#14
Bernard Escudier, Padmanee Sharma, David F McDermott, Saby George, Hans J Hammers, Sandhya Srinivas, Scott S Tykodi, Jeffrey A Sosman, Giuseppe Procopio, Elizabeth R Plimack, Daniel Castellano, Howard Gurney, Frede Donskov, Katriina Peltola, John Wagstaff, Thomas C Gauler, Takeshi Ueda, Huanyu Zhao, Ian M Waxman, Robert J Motzer
No abstract text is available yet for this article.
January 3, 2018: European Urology
https://www.readbyqxmd.com/read/29306511/androgen-receptor-variants-and-castration-resistant-prostate-cancer-looking-back-and-looking-forward
#15
EDITORIAL
Takuma Uo, Cynthia Sprenger
No abstract text is available yet for this article.
January 3, 2018: European Urology
https://www.readbyqxmd.com/read/29289404/postchemotherapy-surgery-for-advanced-urothelial-cancer-another-tool-to-improve-outcome
#16
EDITORIAL
Bernard H Bochner
No abstract text is available yet for this article.
December 27, 2017: European Urology
https://www.readbyqxmd.com/read/29287618/re-brachytherapy-for-patients-with-prostate-cancer-american-society-of-clinical-oncology-cancer-care-ontario-joint-guideline-update
#17
Alberto Bossi
No abstract text is available yet for this article.
December 26, 2017: European Urology
https://www.readbyqxmd.com/read/29275835/a-partner-in-crime-tumor-associated-stroma-and-metastatic-prostate-cancer
#18
EDITORIAL
Michael Fraser, Paul C Boutros, Robert G Bristow
No abstract text is available yet for this article.
December 21, 2017: European Urology
https://www.readbyqxmd.com/read/29275834/re-morbidity-and-mortality-of-locally-advanced-prostate-cancer-a-population-based-analysis-comparing-radical-prostatectomy-versus-external-beam-radiation
#19
https://www.readbyqxmd.com/read/29275833/efficacy-against-human-prostate-cancer-by-prostate-specific-membrane-antigen-specific-transforming-growth-factor-%C3%AE-insensitive-genetically-targeted-cd8-t-cells-derived-from-patients-with-metastatic-castrate-resistant-disease
#20
Qiang Zhang, Brian T Helfand, Benedito A Carneiro, Weijun Qin, Ximing J Yang, Chung Lee, Weipeng Zhang, Francis J Giles, Massimo Cristofanilli, Timothy M Kuzel
Current immunotherapy has limited efficacy on metastatic castrate-resistant prostate cancer (mCRPC). We therefore sought to improve the antitumor ability of mCRPC patient-derived CD8+ T-cells by the endowment of specificity to prostate-specific membrane antigen (PSMA) and insensitivity to immunosuppressant molecule transforming growth factor-β (TGF-ß) under the control of herpes simplex virus-1 thymidine kinase. CD8+ T-cells were collected by leukapheresis and cultured in a Food and Drug Administration-approved Cell Processing Work Station...
December 21, 2017: European Urology
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