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European Urology

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https://www.readbyqxmd.com/read/30224197/-real-world-practice-makes-perfect-ensuring-the-active-component-of-active-surveillance-for-prostate-cancer
#1
EDITORIAL
Adam B Weiner, Edward M Schaeffer, Scott E Eggener
No abstract text is available yet for this article.
September 14, 2018: European Urology
https://www.readbyqxmd.com/read/30224196/reply-to-jeffrey-graham-omar-abdel-rahman-toni-k-choueiri-and-daniel-y-c-heng-s-letter-to-the-editor-re-fabio-conforti-laura-pala-vincenzo-bagnardi-et-al-cancer-immunotherapy-efficacy-and-patients-sex-a-systematic-review-and-meta-analysis-lancet-oncol-2018
#2
LETTER
https://www.readbyqxmd.com/read/30224195/a-nomogram-to-predict-significant-estimated-glomerular-filtration-rate-reduction-after-robotic-partial-nephrectomy
#3
Alberto Martini, Shivaram Cumarasamy, Alp Tuna Beksac, Ronney Abaza, Daniel D Eun, Akshay Bhandari, Ashok K Hemal, James R Porter, Ketan K Badani
BACKGROUND: Decreased functional outcome after partial nephrectomy is associated with overall mortality. OBJECTIVE: To create a model that predicts ≥25% reduction from baseline estimated glomerular filtration rate (eGFR) in patients undergoing robot-assisted partial nephrectomy (RAPN) and to investigate the role of acute kidney injury (AKI) in this patient population. DESIGN, SETTING, AND PARTICIPANTS: A total of 999 patients were identified from a multi-institutional database...
September 14, 2018: European Urology
https://www.readbyqxmd.com/read/30224194/re-henk-g-van-der-poel-roderick-c-n-van-den-bergh-erik-briers-et-al-focal-therapy-in-primary-localised-prostate-cancer-the-european-association-of-urology-position-in-2018-eur-urol-2018-74-84-91
#4
LETTER
https://www.readbyqxmd.com/read/30213523/molecular-subtypes-of-urothelial-bladder-cancer-results-from-a-meta-cohort-analysis-of-2411-tumors
#5
Tuan Zea Tan, Mathieu Rouanne, Kien Thiam Tan, Ruby Yun-Ju Huang, Jean-Paul Thiery
BACKGROUND: Previous molecular subtyping for bladder carcinoma (BLCA) involved <450 samples, with diverse classifications. OBJECTIVE: To identify molecular subtypes by curating a large BLCA dataset. DESIGN, SETTING, AND PARTICIPANTS: Gene expression publicly available were combined and reanalyzed. The dataset contained 2411 unique tumors encompassing non-muscle-invasive (NMIBC) and muscle-invasive BLCA (MIBC). Subtypes were reproduced on The Cancer Genome Atlas, UROMOL, and IMvigor210...
September 10, 2018: European Urology
https://www.readbyqxmd.com/read/30201510/a-joint-statement-from-the-european-association-of-urology-renal-cell-cancer-guidelines-panel-and-the-international-kidney-cancer-coalition-the-rejection-of-ipilimumab-and-nivolumab-for-renal-cancer-by-the-committee-for-medicinal-products-for-human-use-does
#6
LETTER
Axel Bex, Laurence Albiges, Michael Staehler, Karim Bensalah, Rachel H Giles, Saeed Dabestani, Fabian Hofmann, Milan Hora, Markus A Kuczyk, Thomas B Lam, Lorenzo Marconi, Axel S Merseburger, Sergio Fernández-Pello, Rana Tahbaz, Yasmin Abu-Ghanem, Alessandro Volpe, Börje Ljungberg, Bernard Escudier, Thomas Powles
No abstract text is available yet for this article.
September 7, 2018: European Urology
https://www.readbyqxmd.com/read/30195835/reply-to-runqiang-yuan-s-letter-to-the-editor-re-james-t-kearns-anna-v-faino-lisa-f-newcomb-et-al-role-of-surveillance-biopsy-with-no-cancer-as-a-prognostic-marker-for-reclassification-results-from-the-canary-prostate-active-surveillance-study-eur-urol-2018
#7
LETTER
https://www.readbyqxmd.com/read/30195834/low-testosterone-and-prostate-cancer-is-the-protection-real
#8
EDITORIAL
Christopher J D Wallis, Yonah Krakowsky, Antonio Finelli
No abstract text is available yet for this article.
September 5, 2018: European Urology
https://www.readbyqxmd.com/read/30193968/re-riccardo-bertolo-riccardo-autorino-giuseppe-simone-et-al-outcomes-of-robot-assisted-partial-nephrectomy-for-clinical-t2-renal-tumors-a-multicenter-analysis-rosula-collaborative-group-eur-urol-in-press-https-doi-org-10-1016-j-eururo-2018-05-004
#9
LETTER
https://www.readbyqxmd.com/read/30193967/reply-to-zhenjie-wu-and-linhui-wang-s-letter-to-the-editor-re-riccardo-bertolo-riccardo-autorino-giuseppe-simone-et-al-outcomes-of-robot-assisted-partial-nephrectomy-for-clinical-t2-renal-tumors-a-multicenter-analysis-rosula-collaborative-group-eur-urol-in
#10
LETTER
https://www.readbyqxmd.com/read/30181068/multifocal-primary-prostate-cancer-exhibits-high-degree-of-genomic-heterogeneity
#11
Marthe Løvf, Sen Zhao, Ulrika Axcrona, Bjarne Johannessen, Anne Cathrine Bakken, Kristina Totland Carm, Andreas M Hoff, Ola Myklebost, Leonardo A Meza-Zepeda, A Kathrine Lie, Karol Axcrona, Ragnhild A Lothe, Rolf I Skotheim
BACKGROUND: Most primary prostate cancers are multifocal with individual tumors harboring different aggressiveness; however, the genomic heterogeneity among these tumors is poorly understood. OBJECTIVE: To better understand the biological basis for clinical variability among different lesions, we sought to comprehensively characterize the heterogeneity of somatic gene mutations in multifocal prostate cancer. DESIGN, SETTING, AND PARTICIPANTS: High-coverage whole-exome sequencing of 153 frozen tissue samples, taken from two to three distinct tumor foci and one non-cancerous area from each of 41 patients, covering a total of 89 tumor foci...
September 1, 2018: European Urology
https://www.readbyqxmd.com/read/30181067/comparing-prognostic-utility-of-a-single-marker-immunohistochemistry-approach-with-commercial-gene-expression-profiling-following-radical-prostatectomy
#12
Michael S Leapman, Hao G Nguyen, Janet E Cowan, Lingru Xue, Bradley Stohr, Jeffry Simko, Matthew R Cooperberg, Peter R Carroll
BACKGROUND: Despite the availability of numerous genomic predictors of prostate cancer (PCa) outcome, few comparative studies have been performed. OBJECTIVE: To compare the prognostic utility of previously validated immunohistochemical (IHC) markers with an expression-based cell-cycle progression (CCP) score. DESIGN, SETTING, AND PARTICIPANTS: We identified 424 men with localized PCa treated with radical prostatectomy (RP). IHC analysis was performed using a tissue microarray to examine the expression status of PTEN, Ki-67, and ERG compared with previously calculated CCP scores derived from 31 genes normalized to 15 housekeeper genes...
September 1, 2018: European Urology
https://www.readbyqxmd.com/read/30177293/statin-therapy-to-improve-prostate-cancer-outcomes-who-when-and-for-how-long
#13
EDITORIAL
Emma H Allott, Michael R Freeman, Stephen J Freedland
No abstract text is available yet for this article.
August 31, 2018: European Urology
https://www.readbyqxmd.com/read/30177292/new-insights-into-ejaculatory-frequency-and-prostate-cancer-risk-association-causation-or-what-do-we-have-to-lose
#14
EDITORIAL
Marc A Dall'Era, Ralph W De Vere White
No abstract text is available yet for this article.
August 31, 2018: European Urology
https://www.readbyqxmd.com/read/30177291/updated-european-association-of-urology-guidelines-for-cytoreductive-nephrectomy-in-patients-with-synchronous-metastatic-clear-cell-renal-cell-carcinoma
#15
Axel Bex, Laurence Albiges, Börje Ljungberg, Karim Bensalah, Saeed Dabestani, Rachel H Giles, Fabian Hofmann, Milan Hora, Markus A Kuczyk, Thomas B Lam, Lorenzo Marconi, Axel S Merseburger, Sergio Fernández-Pello, Rana Tahbaz, Yasmin Abu-Ghanem, Michael Staehler, Alessandro Volpe, Thomas Powles
Cytoreductive nephrectomy (CN) has been the standard of care in patients with metastatic clear-cell renal cancer who present with the tumour in place. The CARMENA trial compared systemic therapy alone with CN followed by systemic therapy. This article outlines the new guidelines based on these data. PATIENT SUMMARY: The CARMENA trial demonstrates that immediate cytoreductive nephrectomy should no longer be considered the standard of care in patients diagnosed with intermediate and poor risk metastatic renal cell carcinoma when medical treatment is required...
August 31, 2018: European Urology
https://www.readbyqxmd.com/read/30177290/risk-of-becoming-lost-to-follow-up-during-active-surveillance-for-prostate-cancer
#16
Kevin B Ginsburg, Gregory B Auffenberg, Ji Qi, Isaac J Powell, Susan M Linsell, James E Montie, David C Miller, Michael L Cher
Active surveillance (AS) has emerged as the preferred management strategy for many men with prostate cancer (PC); however, insufficient longitudinal monitoring may increase the risk of poor outcomes. We sought to determine rates of patients becoming lost to follow-up (LTFU) and associated risk factors in a large AS cohort. The Michigan Urologic Surgery Improvement Collaborative (MUSIC) maintains a prospective registry of PC patients from 44 academic and community urology practices. Over a 6-yr period (2011-2017), we identified patients managed with AS...
August 31, 2018: European Urology
https://www.readbyqxmd.com/read/30177289/an-insight-into-the-dark-matter-of-kidney-cancer
#17
EDITORIAL
Rohit Mehra
No abstract text is available yet for this article.
August 31, 2018: European Urology
https://www.readbyqxmd.com/read/30177288/re-enzalutamide-in-men-with-nonmetastatic-castration-resistant-prostate-cancer
#18
Malcolm Mason
No abstract text is available yet for this article.
August 31, 2018: European Urology
https://www.readbyqxmd.com/read/30177287/intralesional-and-mechanical-therapies-for-peyronie-s-disease-a-road-anything-but-straight
#19
EDITORIAL
Paolo Verze, Marco Capece, Massimiliano Creta, Mikkel Fode
No abstract text is available yet for this article.
August 31, 2018: European Urology
https://www.readbyqxmd.com/read/30177286/online-professionalism-2018-update-of-european-association-of-urology-uroweb-recommendations-on-the-appropriate-use-of-social-media
#20
REVIEW
Hendrik Borgmann, Matthew Cooperberg, Declan Murphy, Stacy Loeb, James N'Dow, Maria Jose Ribal, Henry Woo, Morgan Rouprêt, Andrew Winterbottom, Carl Wijburg, Manfred Wirth, James Catto, Alexander Kutikov
CONTEXT: Social media (SoMe) has transformed communication among health care professionals by enabling rapid and global information exchange. Yet, the novelty of SoMe and concerns about potential risks continue to be barriers to adoption. OBJECTIVE: To encourage appropriate professional use of SoMe by physicians in concordance with best practices and to update practical guidelines for effective and professional use of these communication technologies. EVIDENCE AQUISITION: The European Association of Urology (EAU; @Uroweb) brought together a committee of SoMe stakeholders in the urology field...
August 31, 2018: European Urology
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