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European Urology

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https://www.readbyqxmd.com/read/30029823/finding-a-needle-in-the-haystack-the-search-for-germline-variants-associated-with-prostate-cancer-clinical-outcomes
#1
EDITORIAL
Kathleen A Cooney, Jennifer L Beebe-Dimmer
No abstract text is available yet for this article.
July 17, 2018: European Urology
https://www.readbyqxmd.com/read/30029822/reply-to-john-t-leppert-and-james-d-brooks-letter-to-the-editor-re-brandon-a-mahal-david-d-yang-natalie-q-wang-et-al-clinical-and-genomic-characterization-of-low-prostate-specific-antigen-high-grade-prostate-cancer-eur-urol-in-press-https-doi-org-10-1016-j
#2
LETTER
https://www.readbyqxmd.com/read/30029821/reply-to-andrea-necchi-antonella-messina-and-alberto-briganti-s-letter-to-the-editor-re-valeria-panebianco-yoshifumi-narumi-ersan-altun-et-al-multiparametric-magnetic-resonance-imaging-for-bladder-cancer-development-of-vi-rads-vesical-imaging-reporting-and
#3
LETTER
https://www.readbyqxmd.com/read/30029820/-to-cut-or-not-to-cut-a-biomolecular-approach-to-metastasectomy-in-metastatic-clear-cell-renal-cell-carcinoma
#4
EDITORIAL
Sergio Bracarda, Annalisa Guida, Claudia Caserta
No abstract text is available yet for this article.
July 17, 2018: European Urology
https://www.readbyqxmd.com/read/30029819/a-molecular-marker-for-eosinophilic-solid-and-cystic-renal-cell-carcinoma
#5
EDITORIAL
Pedram Argani
No abstract text is available yet for this article.
July 17, 2018: European Urology
https://www.readbyqxmd.com/read/30025882/neoadjuvant-chemotherapy-reinforces-antitumour-t-cell-response-in-urothelial-urinary-bladder-cancer
#6
David Krantz, Ciputra Adijaya Hartana, Malin E Winerdal, Markus Johansson, Farhood Alamdari, Tomasz Jakubczyk, Ylva Huge, Firas Aljabery, Karin Palmqvist, A Ali Zirakzadeh, Benny Holmström, Katrine Riklund, Amir Sherif, Ola Winqvist
Evidence indicates that neoadjuvant chemotherapy (NAC) may promote antitumour immune responses by activating T cells. The tumour-draining sentinel node (SN) is a key site to study tumour-specific T cell activation, being the primary immunological barrier against the tumour. In this prospective study, we set out to elucidate the effects of NAC on T cell subsets in the SNs of patients with muscle-invasive urothelial bladder cancer. We found that CD8+ effector T (Teff) cell exhaustion was reduced after NAC treatment, while cytotoxicity was increased...
July 16, 2018: European Urology
https://www.readbyqxmd.com/read/30025881/corrigendum-re-a-larger-prospective-study-is-needed-when-judging-robotic-radical-nephrectomy-eur-urol-2018-74-123-9
#7
Giovanni E Cacciamani, Mihir M Desai, Inderbir S Gill
No abstract text is available yet for this article.
July 16, 2018: European Urology
https://www.readbyqxmd.com/read/30017406/re-exercise-and-cancer-treatment-balancing-patient-needs-lancet-oncol-2018-19-715-cancer-prevention-and-treatment-more-than-exercising
#8
LETTER
Giovanni Lavorgna, Francesco Montorsi, Andrea Salonia
No abstract text is available yet for this article.
July 13, 2018: European Urology
https://www.readbyqxmd.com/read/30017401/simultaneous-bilateral-endoscopic-surgery-for-patients-with-bilateral-upper-tract-urolithiasis-technique-and-outcomes
#9
Guido Giusti, Silvia Proietti, Moises E Rodríguez-Socarrás, Brian H Eisner, Giuseppe Saitta, Guglielmo Mantica, Luca Villa, Andrea Salonia, Francesco Montorsi, Franco Gaboardi
BACKGROUND: The incidence of bilateral and multiple renal stones is not negligible. To date, some sparse data on simultaneous bilateral stone surgery are available in literature showing good outcomes in terms of both effectiveness and safety. OBJECTIVE: To describe our series of patients with bilateral renal stones who underwent simultaneous bilateral endoscopic surgery (SBES), reporting its effectiveness and safety. DESIGN, SETTING, AND PARTICIPANTS: A prospective analysis of 27 consecutive patients who underwent simultaneous flexible ureteroscopy (fURS) in one side and percutaneous nephrolithotomy (PCNL) in the other side for bilateral renal stones was performed...
July 13, 2018: European Urology
https://www.readbyqxmd.com/read/30017405/treatment-strategy-for-newly-diagnosed-t1-high-grade-bladder-urothelial-carcinoma-new-insights-and-updated-recommendations
#10
Zachary Klaassen, Ashish M Kamat, Wassim Kassouf, Paolo Gontero, Humberto Villavicencio, Joaquim Bellmunt, Bas W G van Rhijn, Arndt Hartmann, James W F Catto, Girish S Kulkarni
CONTEXT: High-grade T1 (T1HG) bladder cancer (BCa) has a very high likelihood of disease recurrence and progression to muscle invasion. Radical cystectomy is considered the best chance at cure, albeit with a high risk of morbidity, and is overtreatment for some patients. Treatment with bacillus Calmette-Guerin (BCG) allows bladder preservation but may risk disease progression. OBJECTIVE: To systematically review the current literature on the management of T1HG BCa and provide updated treatment recommendations...
July 12, 2018: European Urology
https://www.readbyqxmd.com/read/30017404/active-surveillance-magnetic-resonance-imaging-study-asist-results-of-a-randomized-multicenter-prospective-trial
#11
Laurence Klotz, Andrew Loblaw, Linda Sugar, Madeline Moussa, David M Berman, Theo Van der Kwast, Danny Vesprini, Laurent Milot, Marlene Kebabdjian, Neil Fleshner, Sangeet Ghai, Joe Chin, Gregory R Pond, Masoom Haider
BACKGROUND AND OBJECTIVE: This study aimed to determine, in men recently diagnosed with grade group 1 (GG1) prostate cancer, if magnetic resonance imaging (MRI) with targeted biopsy could identify a greater proportion of men with GG ≥2 cancer on their confirmatory biopsy compared with systematic biopsies. The study was registered with www.clinicaltrials.gov (NCT01354171). DESIGN, SETTING, AND PARTICIPANTS: This study is a prospective, randomized, multicenter, open-label trial...
July 12, 2018: European Urology
https://www.readbyqxmd.com/read/30017403/prediction-of-aggressive-histology-the-ongoing-dilemma-of-renal-masses-in-the-omics-era
#12
EDITORIAL
Uzoma A Anele, Lance J Hampton, Mayer B Grob, Riccardo Autorino
No abstract text is available yet for this article.
July 12, 2018: European Urology
https://www.readbyqxmd.com/read/30017402/therapeutic-discovery-for-castration-resistant-prostate-cancer-patient-derived-xenograft-modelling-brings-new-options-to-the-table
#13
EDITORIAL
Simon J Crabb
No abstract text is available yet for this article.
July 12, 2018: European Urology
https://www.readbyqxmd.com/read/30017400/the-probability-of-aggressive-versus-indolent-histology-based-on-renal-tumor-size-implications-for-surveillance-and-treatment
#14
Bimal Bhindi, R Houston Thompson, Christine M Lohse, Ross J Mason, Igor Frank, Brian A Costello, Aaron M Potretzke, Robert P Hartman, Theodora A Potretzke, Stephen A Boorjian, John C Cheville, Bradley C Leibovich
BACKGROUND: While the probability of malignant versus benign histology based on renal tumor size has been described, this alone does not sufficiently inform decision-making in the modern era since indolent malignant tumors can be managed with active surveillance. OBJECTIVE: To characterize the probability of aggressive versus indolent histology based on radiographic tumor size. DESIGN, SETTING, AND PARTICIPANTS: We evaluated patients who underwent radical or partial nephrectomy at Mayo Clinic for a pT1-2, pNx/0, M0 solid renal tumor between 1990 and 2010...
July 12, 2018: European Urology
https://www.readbyqxmd.com/read/30017399/re-brandon-a-mahal-david-d-yang-natalie-q-wang-et-al-clinical-and-genomic-characterization-of-low-prostate-specific-antigen-high-grade-prostate-cancer-eur-urol-in-press-https-doi-org-10-1016-j-eururo-2018-01-043
#15
LETTER
https://www.readbyqxmd.com/read/30017398/re-giorgio-gandaglia-carlo-andrea-bravi-paolo-dell-oglio-et-al-the-impact-of-implementation-of-the-european-association-of-urology-guidelines-panel-recommendations-on-reporting-and-grading-complications-on-perioperative-outcomes-after-robot-assisted-radical
#16
LETTER
https://www.readbyqxmd.com/read/30017397/re-gladell-p-paner-walter-m-stadler-donna-e-hansel-rodolfo-montironi-daniel-w-lin-mahul-b-amin-updates-in-the-eighth-edition-of-the-tumor-node-metastasis-staging-classification-for-urologic-cancers-eur-urol-2018-73-560-9-tumour-node-and-metastasis-staging-system
#17
LETTER
https://www.readbyqxmd.com/read/30007820/reply-to-riccardo-bertolo-s-letter-to-the-editor-re-giorgio-gandaglia-carlo-andrea-bravi-paolo-dell-oglio-et-al-the-impact-of-implementation-of-the-european-association-of-urology-guidelines-panel-recommendations-on-reporting-and-grading-complications-on-perioperative
#18
LETTER
https://www.readbyqxmd.com/read/30007819/metabolic-biosynthesis-pathways-identified-from-fecal-microbiome-associated-with-prostate-cancer
#19
Michael A Liss, James Robert White, Martin Goros, Jonathan Gelfond, Robin Leach, Teresa Johnson-Pais, Lai Zhao, Elizabeth Rourke, Joseph Basler, Donna Ankerst, Dimpy P Shah
BACKGROUND: The fecal microbiome is associated with prostate cancer risk factors (obesity, inflammation) and can metabolize and produce various products that may influence cancer but have yet to be defined in prostate cancer. OBJECTIVE: To investigate gut bacterial diversity, identify specific metabolic pathways associated with disease, and develop a microbiome risk profile for prostate cancer. DESIGN, SETTING, AND PARTICIPANTS: After prospective collection of 133 rectal swab samples 2 wk before the transrectal prostate biopsy, we perform 16S rRNA amplicon sequencing on 105 samples (64 with cancer, 41 without cancer)...
July 11, 2018: European Urology
https://www.readbyqxmd.com/read/30007818/getting-the-balance-right-the-benefits-and-uncertainties-of-focal-therapy-for-significant-prostate-cancer
#20
EDITORIAL
Declan G Murphy, Derya Tilki
No abstract text is available yet for this article.
July 11, 2018: European Urology
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