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European Urology

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https://www.readbyqxmd.com/read/28104313/re-long-term-results-of-active-surveillance-in-the-g%C3%A3-teborg-randomized-population-based-prostate-cancer-screening-trial
#1
Panagiotis Kallidonis, Evangelos Liatsikos
No abstract text is available yet for this article.
January 16, 2017: European Urology
https://www.readbyqxmd.com/read/28104312/re-pascal-rischmann-albert-gelet-benjamin-riche-et-al-focal-high-intensity-focused-ultrasound-of-unilateral-localized-prostate-cancer-a-prospective-multicentric-hemiablation-study-of-111-patients-eur-urol-in-press-http-dx-doi-org-10-1016-j-eururo-2016-09-039
#2
LETTER
https://www.readbyqxmd.com/read/28104311/comprehensive-profiling-of-the-androgen-receptor-in-liquid-biopsies-from-castration-resistant-prostate-cancer-reveals-novel-intra-ar-structural-variation-and-splice-variant-expression-patterns
#3
Bram De Laere, Pieter-Jan van Dam, Tom Whitington, Markus Mayrhofer, Emanuela Henao Diaz, Gert Van den Eynden, Jean Vandebroek, Jurgen Del-Favero, Steven Van Laere, Luc Dirix, Henrik Grönberg, Johan Lindberg
BACKGROUND: Expression of the androgen receptor splice variant 7 (AR-V7) is associated with poor response to second-line endocrine therapy in castration-resistant prostate cancer (CRPC). However, a large fraction of nonresponding patients are AR-V7-negative. OBJECTIVE: To investigate if a comprehensive liquid biopsy-based AR profile may improve patient stratification in the context of second-line endocrine therapy. DESIGN, SETTING, AND PARTICIPANTS: Peripheral blood was collected from patients with CRPC (n=30) before initiation of a new line of systemic therapy...
January 16, 2017: European Urology
https://www.readbyqxmd.com/read/28094057/multiparametric-magnetic-resonance-imaging-targeted-biopsy-for-early-detection-of-prostate-cancer-all-that-glitters-is-not-gold
#4
EDITORIAL
Gianluca Giannarini, Alessandro Crestani, Marta Rossanese, Vincenzo Ficarra
No abstract text is available yet for this article.
January 13, 2017: European Urology
https://www.readbyqxmd.com/read/28094056/re-the-role-of-adjuvant-radiotherapy-in-pathologically-lymph-node-positive-prostate-cancer
#5
Matthias May, Christian G Stief, Sabine D Brookman-May
No abstract text is available yet for this article.
January 13, 2017: European Urology
https://www.readbyqxmd.com/read/28094055/renal-cell-carcinoma-with-isolated-lymph-node-involvement-long-term-natural-history-and-predictors-of-oncologic-outcomes-following-surgical-resection
#6
Boris Gershman, Daniel M Moreira, R Houston Thompson, Stephen A Boorjian, Christine M Lohse, Brian A Costello, John C Cheville, Bradley C Leibovich
BACKGROUND: Renal cell carcinoma (RCC) with isolated lymph node (LN) involvement has historically been associated with poor prognosis. However, a subset of patients may experience long-term survival. OBJECTIVE: To examine the natural history of RCC with isolated LN involvement following surgical resection with long-term follow-up, and to evaluate clinicopathologic features associated with disease progression and survival. DESIGN, SETTING, AND PARTICIPANTS: A total of 138 patients with isolated pN1M0 RCC underwent partial or radical nephrectomy and LN dissection from 1980 to 2010...
January 13, 2017: European Urology
https://www.readbyqxmd.com/read/28094054/re-prediction-of-lymph-node-metastasis-in-patients-with-bladder-cancer-using-whole-transcriptome-gene-expression-signatures
#7
Beat Roth
No abstract text is available yet for this article.
January 13, 2017: European Urology
https://www.readbyqxmd.com/read/28089305/reply-to-thomas-zilli-gilles-crehange-and-olivier-chapet-s-letter-to-the-editor-re-pascal-rischmann-albert-gelet-benjamin-riche-et-al-focal-high-intensity-focused-ultrasound-of-unilateral-localized-prostate-cancer-a-prospective-multicentric-hemiablation-study
#8
LETTER
https://www.readbyqxmd.com/read/28089304/management-of-prostate-cancer-in-elderly-patients-recommendations-of-a-task-force-of-the-international-society-of-geriatric-oncology
#9
REVIEW
Jean-Pierre Droz, Gilles Albrand, Silke Gillessen, Simon Hughes, Nicolas Mottet, Stéphane Oudard, Heather Payne, Martine Puts, Gilbert Zulian, Lodovico Balducci, Matti Aapro
CONTEXT: Prostate cancer is the most frequent male cancer. Since the median age of diagnosis is 66 yr, many patients require both geriatric and urologic evaluation if treatment is to be tailored to individual circumstances including comorbidities and frailty. OBJECTIVE: To update the 2014 International Society of Geriatric Oncology (SIOG) guidelines on prostate cancer in men aged >70 yr. The update includes new material on health status evaluation and the treatment of localised, advanced, and castrate-resistant disease...
January 11, 2017: European Urology
https://www.readbyqxmd.com/read/28089303/practical-polling-for-prostate-cancer-ar-v7-based-treatment-selection
#10
EDITORIAL
Alastair D Lamb, Mitchell G Lawrence, Shahneen Sandhu
No abstract text is available yet for this article.
January 11, 2017: European Urology
https://www.readbyqxmd.com/read/28087094/in-defense-of-randomized-clinical-trials-in-surgery-let-us-not-forget-archie-cochrane-s-legacy
#11
EDITORIAL
James W F Catto, Jane M Blazeby, Lars Holmberg, Freddie C Hamdy, Julia Brown
No abstract text is available yet for this article.
January 10, 2017: European Urology
https://www.readbyqxmd.com/read/28081860/long-term-outcomes-after-bladder-preserving-tri-modality-therapy-for-patients-with-muscle-invasive-bladder-cancer-an-updated-analysis-of-the-massachusetts-general-hospital-experience
#12
Nicholas J Giacalone, William U Shipley, Rebecca H Clayman, Andrzej Niemierko, Michael Drumm, Niall M Heney, Marc D Michaelson, Richard J Lee, Philip J Saylor, Matthew F Wszolek, Adam S Feldman, Douglas M Dahl, Anthony L Zietman, Jason A Efstathiou
BACKGROUND: Tri-modality therapy (TMT) is a recognized treatment strategy for selected patients with muscle-invasive bladder cancer (MIBC). OBJECTIVE: Report long-term outcomes of patients with MIBC treated by TMT. DESIGN, SETTING, AND PARTICIPANTS: Four hundred and seventy-five patients with cT2-T4a MIBC were enrolled on protocols or treated as per protocol at the Massachusetts General Hospital between 1986 and 2013. INTERVENTION: Patients underwent transurethral resection of bladder tumor followed by concurrent radiation and chemotherapy...
January 9, 2017: European Urology
https://www.readbyqxmd.com/read/28073601/re-management-of-nonmuscle-invasive-bladder-cancer-a-comprehensive-analysis-of-guidelines-from-the-unites-states-europe-and-asia
#13
Ralph de Vere White
No abstract text is available yet for this article.
January 7, 2017: European Urology
https://www.readbyqxmd.com/read/28073600/e-cigarettes-and-urologic-health-a-collaborative-review-of-toxicology-epidemiology-and-potential-risks
#14
REVIEW
Liam Bourke, Linda Bauld, Christopher Bullen, Marcus Cumberbatch, Edward Giovannucci, Farhad Islami, Hayden McRobbie, Debra T Silverman, James W F Catto
CONTEXT: Use of electronic cigarettes (ECs) is on the rise in most high-income countries. Smoking conventional cigarettes is a known risk factor for urologic malignancy incidence, progression, and mortality, as well as for other urologic health indicators. The potential impact of EC use on urologic health is therefore of clinical interest to the urology community. OBJECTIVE: To review the available data on current EC use, including potential benefits in urologic patients, potential issues linked to toxicology of EC constituents, and how this might translate into urologic health risks...
January 7, 2017: European Urology
https://www.readbyqxmd.com/read/28069289/liquid-biopsy-analysis-of-fgfr3-and-pik3ca-hotspot-mutations-for-disease-surveillance-in-bladder-cancer
#15
Emil Christensen, Karin Birkenkamp-Demtröder, Iver Nordentoft, Søren Høyer, Kirstin van der Keur, Kim van Kessel, Ellen Zwarthoff, Mads Agerbæk, Torben Falck Ørntoft, Jørgen Bjerggaard Jensen, Lars Dyrskjøt
BACKGROUND: Disease surveillance in patients with bladder cancer is important for early diagnosis of progression and metastasis and for optimised treatment. OBJECTIVE: To develop urine and plasma assays for disease surveillance for patients with FGFR3 and PIK3CA tumour mutations. DESIGN, SETTING, AND PARTICIPANTS: Droplet digital polymerase chain reaction (ddPCR) assays were developed and tumour DNA from two patient cohorts was screened for FGFR3 and PIK3CA hotspot mutations...
January 6, 2017: European Urology
https://www.readbyqxmd.com/read/28065538/re-daniel-e-spratt-herbert-a-vargas-zachary-s-zumsteg-et-al-patterns-of-lymph-node-failure-after-dose-escalated-radiotherapy-implications-for-extended-pelvic-lymph-node-coverage-eur-urol-in-press-http-dx-doi-org-10-1016-j-eururo-2016-07-043-high-dose-radiotherapy
#16
LETTER
https://www.readbyqxmd.com/read/28065537/re-inherited-dna-repair-gene-mutations-in-men-with-metastatic-prostate-cancer
#17
David G McLeod, Shiv Srivastava
No abstract text is available yet for this article.
January 5, 2017: European Urology
https://www.readbyqxmd.com/read/28063613/why-and-where-do-we-miss-significant-prostate-cancer-with-multi-parametric-magnetic-resonance-imaging-followed-by-magnetic-resonance-guided-and-transrectal-ultrasound-guided-biopsy-in-biopsy-na%C3%A3-ve-men
#18
Martijn G Schouten, Marloes van der Leest, Morgan Pokorny, Martijn Hoogenboom, Jelle O Barentsz, Les C Thompson, Jurgen J Fütterer
BACKGROUND: Knowledge of significant prostate (sPCa) locations being missed with magnetic resonance (MR)- and transrectal ultrasound (TRUS)-guided biopsy (Bx) may help to improve these techniques. OBJECTIVE: To identify the location of sPCa lesions being missed with MR- and TRUS-Bx. DESIGN, SETTING, AND PARTICIPANTS: In a referral center, 223 consecutive Bx-naive men with elevated prostate specific antigen level and/or abnormal digital rectal examination were included...
January 4, 2017: European Urology
https://www.readbyqxmd.com/read/28043707/salvage-lymph-node-dissection-for-node-only-recurrence-of-prostate-cancer-ready-for-prime-time
#19
EDITORIAL
Nazareno Suardi, Alberto Briganti, Giorgio Gandaglia, Nicola Fossati, Francesco Montorsi
Several studies show that salvage lymph-node dissection for node-only recurrence of prostate cancer after radical treatment might represent a viable treatment modality for node-only recurrent PCa. However, as long as high quality data is not available, this approach should still be considered experimental.
December 30, 2016: European Urology
https://www.readbyqxmd.com/read/28043706/re-ian-d-davis-wanling-xie-carmel-pezaro-et-al-efficacy-of-second-line-targeted-therapy-for-renal-cell-carcinoma-according-to-change-from-baseline-in-international-metastatic-renal-cell-carcinoma-database-consortium-prognostic-category-eur-urol-in-press-http
#20
LETTER
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