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European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology

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https://www.readbyqxmd.com/read/28182564/global-strategy-for-the-diagnosis-management-and-prevention-of-chronic-obstructive-lung-disease-2017-report-gold-executive-summary
#1
Claus F Vogelmeier, Gerard J Criner, Fernando J Martinez, Antonio Anzueto, Peter J Barnes, Jean Bourbeau, Bartolome R Celli, Rongchang Chen, Marc Decramer, Leonardo M Fabbri, Peter Frith, David M G Halpin, M Victorina López Varela, Masaharu Nishimura, Nicolas Roche, Roberto Rodriguez-Roisin, Don D Sin, Dave Singh, Robert Stockley, Jørgen Vestbo, Jadwiga A Wedzicha, Alvar Agusti
This Executive Summary of the Global Strategy for the Diagnosis, Management, and Prevention of COPD (GOLD) 2017 Report focuses primarily on the revised and novel parts of the document. The most significant changes include: 1) the assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation. ABCD groups are now proposed to be derived exclusively from patient symptoms and their history of exacerbations; 2) for each of the groups A to D, escalation strategies for pharmacological treatments are proposed; 3) the concept of deescalation of therapy is introduced in the treatment assessment scheme; 4) nonpharmacologic therapies are comprehensively presented and; 5) the importance of comorbid conditions in managing COPD is reviewed...
February 24, 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28182572/can-tuberculosis-patients-in-resource-constrained-settings-afford-chest-radiography
#2
LETTER
Debora Pedrazzoli, Marek Lalli, Delia Boccia, Rein Houben, Katharina Kranzer
No abstract text is available yet for this article.
December 23, 2016: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28182571/poor-adherence-to-management-guidelines-in-nontuberculous-mycobacterial-pulmonary-diseases
#3
LETTER
Jakko van Ingen, Dirk Wagner, Jack Gallagher, Kozo Morimoto, Christoph Lange, Charles S Haworth, R Andres Floto, Jennifer Adjemian, D Rebecca Prevots, David E Griffith
No abstract text is available yet for this article.
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28182570/long-term-outcome-and-safety-of-prolonged-bedaquiline-treatment-for-multidrug-resistant-tuberculosis
#4
Lorenzo Guglielmetti, Marie Jaspard, Damien Le Dû, Marie Lachâtre, Dhiba Marigot-Outtandy, Christine Bernard, Nicolas Veziris, Jérôme Robert, Yazdan Yazdanpanah, Eric Caumes, Mathilde Fréchet-Jachym
Bedaquiline, a recently approved drug for the treatment of multidrug-resistant tuberculosis (MDR-TB), is recommended for a duration of 24 weeks. There are scarce data on patients treated with this drug outside clinical trials.All MDR-TB patients who started treatment from January 1, 2011 to December 31, 2013 and received ≥30 days of bedaquiline were included in a multicentre observational cohort.Among 45 MDR-TB patients, 53% harboured isolates resistant to both fluoroquinolones and second-line injectables, and 38% harboured isolates resistant to one of these drug classes...
December 22, 2016: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28182568/rapid-emergence-of-mycobacterium-tuberculosis-bedaquiline-resistance-lessons-to-avoid-repeating-past-errors
#5
LETTER
Nicolas Veziris, Christine Bernard, Lorenzo Guglielmetti, Damien Le Du, Dhiba Marigot-Outtandy, Marie Jaspard, Eric Caumes, Isabelle Lerat, Christophe Rioux, Yazdan Yazdanpanah, Angelica Tiotiu, Nadine Lemaitre, Florence Brossier, Vincent Jarlier, Jerome Robert, Wladimir Sougakoff, Alexandra Aubry
No abstract text is available yet for this article.
December 22, 2016: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28182566/measurement-of-tidal-breathing-flows-in-infants-using-impedance-pneumography
#6
Leo Pekka Malmberg, Ville-Pekka Seppä, Anne Kotaniemi-Syrjänen, Kristiina Malmström, Merja Kajosaari, Anna S Pelkonen, Jari Viik, Mika J Mäkelä
Tidal breathing flow volume (TBFV) profiles have been used to characterise altered lung function. Impedance pneumography (IP) is a novel option for assessing TBFV curves noninvasively. The aim of this study was to extend the application of IP for infants and to estimate the agreement between IP and direct pneumotachograph (PNT) measurements in assessing tidal airflow and flow-derived indices.Tidal flow profiles were recorded for 1 min simultaneously with PNT and uncalibrated IP at baseline in 44 symptomatic infants, and after methacholine-induced bronchoconstriction in a subgroup (n=20)...
December 19, 2016: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28182565/comparison-of-the-dyspnoea-12-and-multidimensional-dyspnoea-profile-in-people-with-copd
#7
Marie T Williams, David John, Peter Frith
We directly compared convergent, discriminant and concurrent validity of the Dyspnoea-12 (D-12) and Multidimensional Dyspnoea Profile (MDP) in people with chronic obstructive pulmonary disease.Breathlessness measures (D-12, MDP, visual analogue scales and descriptors) were completed for two focal periods (daily life and end of walk test). Instrument structure (D-12 and MDP item grouping) was assessed with factor analysis. Differences between airflow severity stage and focal periods (ANOVA, t-test and Chi-squared test), associations between D-12 and MDP (r, r(2) for static pulmonary function, 6-min walk test and self-reported measures of impairment) and individual consistency for comparable items of the D-12 and MDP (McNemar's test) were assessed...
December 19, 2016: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28232421/rare-respiratory-diseases-are-ready-for-primetime-from-rare-disease-day-to-the-european-reference-networks
#8
EDITORIAL
Marc Humbert, Thomas O Wagner
No abstract text is available yet for this article.
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28232420/impact-of-pulmonary-vascular-volume-on-mortality-in-ipf-is-it-time-to-reconsider-the-role-of-vasculature-in-disease-pathogenesis-and-progression
#9
LETTER
Joseph Jacob, Andrew G Nicholson, Athol U Wells, David M Hansell
No abstract text is available yet for this article.
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28232419/evaluation-of-the-incidence-of-rare-diseases-difficulties-and-uncertainties-the-example-of-chronic-thromboembolic-pulmonary-hypertension
#10
EDITORIAL
Gérald Simonneau, Marius M Hoeper
No abstract text is available yet for this article.
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28232418/hypertonic-saline-in-patients-with-primary-ciliary-dyskinesia-on-the-road-to-evidence-based-treatment-for-a-rare-lung-disease
#11
EDITORIAL
Claudia E Kuehni, Myrofora Goutaki, Helene E Kobbernagel
No abstract text is available yet for this article.
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28232417/impact-of-pulmonary-vascular-volume-on-mortality-in-ipf-is-it-time-to-reconsider-the-role-of-vasculature-in-disease-pathogenesis-and-progression
#12
LETTER
Ermanno Puxeddu, Francesco Cavalli, Gabriella Pezzuto, Elisa Teodori, Paola Rogliani
No abstract text is available yet for this article.
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28232416/the-yin-and-yang-of-idiopathic-pulmonary-fibrosis
#13
EDITORIAL
Michael Kreuter, Vincent Cottin
No abstract text is available yet for this article.
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28232415/clinical-relevance-of-pulmonary-amyloidosis-an-analysis-of-76-autopsy-derived-cases
#14
LETTER
Kamonpun Ussavarungsi, Eunhee S Yi, Joseph J Maleszewski, Paul J Kurtin, Surenda Dasari, Jason D Theis, Angela Dispenzieri, Jay H Ryu
No abstract text is available yet for this article.
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28232414/heat-shock-protein-a-hot-topic-in-idiopathic-pulmonary-fibrosis
#15
EDITORIAL
Philippe Bonniaud, Pierre-Simon Bellaye, Olivier Burgy, Martin Kolb
No abstract text is available yet for this article.
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28232413/within-day-test-retest-reliability-of-the-6-min-walk-test-in-patients-with-pulmonary-fibrosis
#16
LETTER
Ada E M Bloem, Marcel Veltkamp, Jan W H Custers, Hanneke M Dolk, Jan C Grutters, Martijn A Spruit
No abstract text is available yet for this article.
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28232412/volatolomics-of-breath-as-an-emerging-frontier-in-pulmonary-arterial-hypertension
#17
REVIEW
Morad K Nakhleh, Hossam Haick, Marc Humbert, Sylvia Cohen-Kaminsky
There is accumulating evidence in support of the significant improvement in survival rates and clinical outcomes when pulmonary arterial hypertension (PAH) is diagnosed at early stages. Nevertheless, it remains a major clinical challenge and the outcomes are dependent on invasive right heart catheterisation.Resulting from pathophysiological processes and detectable in exhaled breath, volatile organic compounds (VOCs) have been proposed as noninvasive biomarkers for PAH. Studies have confirmed significant alterations of the exhaled VOCs among PAH patients when compared to controls and/or patients with other respiratory diseases...
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28232411/incidence-of-chronic-thromboembolic-pulmonary-hypertension-after-acute-pulmonary-embolism-a-contemporary-view-of-the-published-literature
#18
Yvonne M Ende-Verhaar, Suzanne C Cannegieter, Anton Vonk Noordegraaf, Marion Delcroix, Piotr Pruszczyk, Albert T A Mairuhu, Menno V Huisman, Frederikus A Klok
The incidence of chronic thromboembolic pulmonary hypertension (CTEPH) after pulmonary embolism (PE) is relevant for management decisions but is currently unknown.We performed a meta-analysis of studies including consecutive PE patients followed for CTEPH. Study cohorts were predefined as "all comers", "survivors" or "survivors without major comorbidities". CTEPH incidences were calculated using random effects models.We selected 16 studies totalling 4047 PE patients who were mostly followed up for >2-years...
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28232410/a-randomised-controlled-trial-on-the-effect-of-inhaled-hypertonic-saline-on-quality-of-life-in-primary-ciliary-dyskinesia
#19
Tamara Paff, Johannes M A Daniels, Els J Weersink, René Lutter, Anton Vonk Noordegraaf, Eric G Haarman
Hypertonic saline inhalation lowers airway mucous viscosity. Increased cough transportability may improve quality of life (QoL) in primary ciliary dyskinesia (PCD).In this randomised controlled trial (RCT), PCD patients received twice-daily inhalations of hypertonic (7%) saline or isotonic (0.9%) saline for 12 weeks, with 4 weeks washout during crossover. Primary outcome was change in QoL measured by the St George's Respiratory Questionnaire (SGRQ) total score. Secondary outcomes were SGRQ subscores, Quality of Life Questionnaire-Bronchiectasis (QoL-B) scores, lower respiratory tract infection symptoms, exacerbations, spirometry, systemic and sputum inflammatory markers, adherence, and adverse events...
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28232409/baseline-characteristics-of-idiopathic-pulmonary-fibrosis-analysis-from-the-australian-idiopathic-pulmonary-fibrosis-registry
#20
Helen E Jo, Ian Glaspole, Christopher Grainge, Nicole Goh, Peter M A Hopkins, Yuben Moodley, Paul N Reynolds, Sally Chapman, E Haydn Walters, Christopher Zappala, Heather Allan, Gregory J Keir, Andrew Hayen, Wendy A Cooper, Annabelle M Mahar, Samantha Ellis, Sacha Macansh, Tamera J Corte
7The prevalence of idiopathic pulmonary fibrosis (IPF), a fatal and progressive lung disease, is estimated at 1.25-63 out of 100 000, making large population studies difficult. Recently, the need for large longitudinal registries to study IPF has been recognised.The Australian IPF Registry (AIPFR) is a national registry collating comprehensive longitudinal data of IPF patients across Australia. We explored the characteristics of this IPF cohort and the effect of demographic and physiological parameters and specific management on mortality...
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
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