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European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology

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https://www.readbyqxmd.com/read/28931673/10%C3%A2-years-since-torch-shining-a-new-light-on-the-risks-of-inhaled-corticosteroids-in-copd
#1
EDITORIAL
James D Chalmers, Holly R Keir
No abstract text is available yet for this article.
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931672/new-drug-targets-for-chronic-cough-research-you-can-literally-sink-your-teeth-into
#2
EDITORIAL
Caroline J Jolley, Surinder S Birring
No abstract text is available yet for this article.
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931671/can-epidemiological-studies-determine-the-productivity-related-burden-of-copd
#3
EDITORIAL
Sanja Stanojevic
No abstract text is available yet for this article.
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931670/the-validation-of-the-sit-to-stand-test-for-copd-patients
#4
LETTER
Sarah Crook, Milo A Puhan, Anja Frei
No abstract text is available yet for this article.
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931669/two-valves-in-the-pharynx
#5
EDITORIAL
Shiroh Isono
No abstract text is available yet for this article.
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931668/the-validation-of-the-sit-to-stand-test-for-copd-patients
#6
LETTER
Arnaud Chambellan, Simon Nusinovici, Trija Vaidya, Pierre-Antoine Gourraud, Claire de Bisschop
No abstract text is available yet for this article.
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931667/an-invisible-disease-severe-asthma-is-more-than-just-bad-asthma
#7
EDITORIAL
Sally E Wenzel, Sheila Brillhart, Kristin Nowack
No abstract text is available yet for this article.
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931666/trpa1-activation-in-a-human-sensory-neuronal-model-relevance-to-cough-hypersensitivity
#8
Rebecca Clarke, Kevin Monaghan, Imad About, Caoimhin S Griffin, Gerard P Sergeant, Ikhlas El Karim, J Graham McGeown, S Louise Cosby, Timothy M Curtis, Lorcan P McGarvey, Fionnuala T Lundy
The cough reflex becomes hyperresponsive in acute and chronic respiratory diseases, but understanding the underlying mechanism is hampered by difficulty accessing human tissue containing both nerve endings and neuronal cell bodies. We refined an adult stem cell sensory neuronal model to overcome the limited availability of human neurones and applied the model to study transient receptor potential ankyrin 1 (TRPA1) channel expression and activation.Human dental pulp stem cells (hDPSCs) were differentiated towards a neuronal phenotype, termed peripheral neuronal equivalents (PNEs)...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931665/evaluation-of-criteria-for-exercise-induced-pulmonary-hypertension-in-patients-with-resting-pulmonary-hypertension
#9
LETTER
Christopher J Mullin, Steven Hsu, Kaushik Amancherla, Alison Wand, Parker Rhodes, Peter J Leary, Monica Mukherjee, Rachel L Damico, Todd M Kolb, Stephen C Mathai, Paul M Hassoun, Ryan J Tedford
No abstract text is available yet for this article.
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931664/determinants-of-diaphragm-thickening-fraction-during-mechanical-ventilation-an-ancillary-study-of-a-randomised-trial
#10
LETTER
Emmanuel Vivier, Ferran Roche-Campo, Laurent Brochard, Armand Mekontso Dessap
No abstract text is available yet for this article.
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931663/targeting-fatty-acid-amide-hydrolase-as-a-therapeutic-strategy-for-antitussive-therapy
#11
Michael A Wortley, John J Adcock, Eric D Dubuis, Sarah A Maher, Sara J Bonvini, Isabelle Delescluse, Ross Kinloch, Gordon McMurray, Christelle Perros-Huguet, Marianthi Papakosta, Mark A Birrell, Maria G Belvisi
Cough is the most common reason to visit a primary care physician, yet it remains an unmet medical need. Fatty acid amide hydrolase (FAAH) is an enzyme that breaks down endocannabinoids, and inhibition of FAAH produces analgesic and anti-inflammatory effects. Cannabinoids inhibit vagal sensory nerve activation and the cough reflex, so it was hypothesised that FAAH inhibition would produce antitussive activity via elevation of endocannabinoids.Primary vagal ganglia neurons, tissue bioassay, in vivo electrophysiology and a conscious guinea pig cough model were utilised to investigate a role for fatty acid amides in modulating sensory nerve activation in vagal afferents...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931662/-i-have-lost-in-every-facet-of-my-life-the-hidden-burden-of-severe-asthma
#12
Juliet M Foster, Vanessa M McDonald, Michael Guo, Helen K Reddel
People with severe asthma are thought to face a sizeable daily disease burden. This study aimed to explore the little-known life experiences of people living with severe asthma.Adults with severe asthma were invited for telephone interview. Semistructured interviews were conducted until no new themes emerged. The 25 interviews were recorded, transcribed and analysed thematically.Four themes emerged. 1) "The body as a hindrance": severe asthma placed broad limits on life from daily chores to career, relationships and family life that left interviewees feeling emotionally distressed...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931661/unemployment-in-chronic-airflow-obstruction-around-the-world-results-from-the-bold-study
#13
Rune Grønseth, Marta Erdal, Wan C Tan, Daniel O Obaseki, Andre F S Amaral, Thorarinn Gislason, Sanjay K Juvekar, Parvaiz A Koul, Michael Studnicka, Sundeep Salvi, Peter Burney, A Sonia Buist, William M Vollmer, Ane Johannessen
We aimed to examine associations between chronic airflow obstruction (CAO) and unemployment across the world.Cross-sectional data from 26 sites in the Burden of Obstructive Lung Disease (BOLD) study were used to analyse effects of CAO on unemployment. Odds ratios for unemployment in subjects aged 40-65 years were estimated using a multilevel mixed-effects generalised linear model with study site as random effect. Site-by-site heterogeneity was assessed using individual participant data meta-analyses.Out of 18 710 participants, 11...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931660/predicting-epiglottic-collapse-in-patients-with-obstructive-sleep-apnoea
#14
Ali Azarbarzin, Melania Marques, Scott A Sands, Sara Op de Beeck, Pedro R Genta, Luigi Taranto-Montemurro, Camila M de Melo, Ludovico Messineo, Olivier M Vanderveken, David P White, Andrew Wellman
Obstructive sleep apnoea (OSA) is characterised by pharyngeal obstruction occurring at different sites. Endoscopic studies reveal that epiglottic collapse renders patients at higher risk of failed oral appliance therapy or accentuated collapse on continuous positive airway pressure. Diagnosing epiglottic collapse currently requires invasive studies (imaging and endoscopy). As an alternative, we propose that epiglottic collapse can be detected from the distinct airflow patterns it produces during sleep.23 OSA patients underwent natural sleep endoscopy...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931659/the-risk-of-mycobacterial-infections-associated-with-inhaled-corticosteroid-use
#15
Sarah K Brode, Michael A Campitelli, Jeffrey C Kwong, Hong Lu, Alex Marchand-Austin, Andrea S Gershon, Frances B Jamieson, Theodore K Marras
Inhaled corticosteroid (ICS) use is associated with an increased risk of pneumonia. This study was performed to determine if ICS use is associated with an increased risk of nontuberculous mycobacterial pulmonary disease (NTM-PD) or tuberculosis (TB).We conducted a population-based nested case-control study using linked laboratory and health administrative databases in Ontario, Canada, including adults aged ≥66 years with treated obstructive lung disease (i.e. asthma, chronic obstructive pulmonary disease (COPD) or asthma-COPD overlap syndrome) between 2001 and 2013...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28931658/erj-september-podcast-the-hidden-burden-of-severe-asthma
#16
(no author information available yet)
No abstract text is available yet for this article.
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28899941/after-the-asthmas-star-wars-and-star-trek
#17
EDITORIAL
Andrew Bush, Ian D Pavord
No abstract text is available yet for this article.
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28899940/treating-anxious-expectations-can-improve-dyspnoea-in-patients-with-copd
#18
EDITORIAL
Andreas von Leupoldt
No abstract text is available yet for this article.
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28899939/work-productivity-loss-in-mild-to-moderate-copd-lessons-learned-from-the-cancold-study
#19
LETTER
Riany de Sousa Sena, Sara Ahmed, Wan C Tan, Pei Z Li, Laura Labonté, Shawn D Aaron, Andrea Benedetti, Kenneth R Chapman, B Walker, J Mark Fitzgerald, Paul Hernandez, François Maltais, Darcy D Marciniuk, Denis E O'Donnell, Don D Sin, Jean Bourbeau
No abstract text is available yet for this article.
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28899938/phase-three-studies-of-biologics-for-severe-asthma-could-do-better
#20
EDITORIAL
Douglas S Robinson, Harsha H Kariyawasam, Liam G Heaney
No abstract text is available yet for this article.
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
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