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European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology

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https://www.readbyqxmd.com/read/29146609/inflammation-age-and-changing-microbiology-the-search-for-causation-in-the-cystic-fibrosis-airways
#1
EDITORIAL
Geraint B Rogers
No abstract text is available yet for this article.
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29146608/closing-the-gap-in-surveillance-of-tuberculosis-and-hiv-co-infection-a-european-perspective-on-the-need-for-clinician-public-health-alliances
#2
EDITORIAL
Marieke J van der Werf, Giovanni Sotgiu, Masoud Dara
No abstract text is available yet for this article.
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29146607/proof-of-concept-that-most-borderline-quantiferon-results-are-true-antigen-specific-responses
#3
LETTER
Jonathan W Uzorka, Lucia J M Kroft, Jaap A Bakker, Erik W van Zwet, Erik Huisman, Corine Knetsch-Prins, Cornelis J van der Zwan, Tom H M Ottenhoff, Sandra M Arend
No abstract text is available yet for this article.
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29146606/restricted-magnetic-resonance-diffusion-of-lung-consolidation-is-not-specific-for-respiratory-exacerbation
#4
LETTER
Gaël Dournes, François Laurent
No abstract text is available yet for this article.
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29146605/cardiac-safety-of-bedaquiline-a-systematic-and-critical-analysis-of-the-evidence
#5
EDITORIAL
Emanuele Pontali, Giovanni Sotgiu, Simon Tiberi, Lia D'Ambrosio, Rosella Centis, Giovanni B Migliori
No abstract text is available yet for this article.
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29146604/the-effect-of-treatment-for-sleep-apnoea-on-determinants-of-blood-pressure-control
#6
Raquel Casitas, Elisabet Martínez-Cerón, Raúl Galera, Carolina Cubillos-Zapata, María Jesús González-Villalba, Isabel Fernández-Navarro, Begoña Sánchez, Aldara García-Sánchez, Ester Zamarrón, Francisco García-Río
Our aim was to assess the effect of continuous positive airway pressure (CPAP) on the nocturnal evolution of peripheral chemosensitivity, renin-angiotensin-aldosterone system activity, sympathetic tone and endothelial biomarkers in obstructive sleep apnoea (OSA) patients with isolated nocturnal hypertension (INH) or day-night sustained hypertension (D-NSH).In a crossover randomised trial, 32 OSA patients newly diagnosed with hypertension and without antihypertensive treatment were randomly assigned to 12 weeks of CPAP or sham CPAP...
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29146603/tuberculosis-patients-with-unknown-hiv-status-in-the-netherlands-analysing-underreporting-and-lack-of-testing
#7
LETTER
Maike Arnoldussen, Henrieke Schimmel, Eline Op de Coul, Susan van den Hof, Gerard de Vries
No abstract text is available yet for this article.
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29146602/donor-specific-and-nonspecific-hla-antibodies-and-outcome-post-lung-transplantation
#8
Stijn E Verleden, Bart M Vanaudenaerde, Marie-Paul Emonds, Dirk E Van Raemdonck, Arne P Neyrinck, Geert M Verleden, Robin Vos
Donor-specific antibodies (DSAs) against human leukocyte antigen (HLA) are associated with chronic lung allograft dysfunction (CLAD) and mortality post lung transplantation, but data concerning prevalence, time of onset, persistence and effects on long-term outcome remain scarce.We assessed the association between HLA antibodies and CLAD-free and graft survival in a cohort of 362 patients. We stratified our analysis according to DSA status, persistence of antibodies and timing of antibodies (pre-transplant, early or late post-transplant)...
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29146601/airway-microbiota-across-age-and-disease-spectrum-in-cystic-fibrosis
#9
Edith T Zemanick, Brandie D Wagner, Charles E Robertson, Richard C Ahrens, James F Chmiel, John P Clancy, Ronald L Gibson, William T Harris, Geoffrey Kurland, Theresa A Laguna, Susanna A McColley, Karen McCoy, George Retsch-Bogart, Kurtis T Sobush, Pamela L Zeitlin, Mark J Stevens, Frank J Accurso, Scott D Sagel, J Kirk Harris
Our objectives were to characterise the microbiota in cystic fibrosis (CF) bronchoalveolar lavage fluid (BALF), and determine its relationship to inflammation and disease status.BALF from paediatric and adult CF patients and paediatric disease controls undergoing clinically indicated bronchoscopy was analysed for total bacterial load and for microbiota by 16S rDNA sequencing.We examined 191 BALF samples (146 CF and 45 disease controls) from 13 CF centres. In CF patients aged <2 years, nontraditional taxa (e...
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29122923/-immune-checkpoint-inhibitors-associated-with-interstitial-lung-disease-in-cancer-patients-myriam-delaunay-jacques-cadranel-am%C3%A3-lie-lusque-nicolas-meyer-val%C3%A3-rie-gounant-denis-moro-sibilot-jean-marie-michot-judith-raimbourg-nicolas-girard-florian-guisier-david
#10
https://www.readbyqxmd.com/read/29122922/elucidating-progression-of-early-cystic-fibrosis-lung-disease
#11
EDITORIAL
Kathryn Ramsey, Felix Ratjen, Philipp Latzin
No abstract text is available yet for this article.
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29122921/bedaquiline-how-better-to-use-it
#12
LETTER
Jose A Caminero, Alberto Piubello, Anna Scardigli, Giovanni Battista Migliori
No abstract text is available yet for this article.
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29122920/digital-health-to-end-tuberculosis-in-the-sustainable-development-goals-era-achievements-evidence-and-future-perspectives
#13
EDITORIAL
Dennis Falzon, Giovanni Battista Migliori, Ernesto Jaramillo, Karin Weyer, Guy Joos, Mario Raviglione
No abstract text is available yet for this article.
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29122919/action-levels-for-indoor-radon-different-risks-for-the-same-lung-carcinogen
#14
EDITORIAL
Alberto Ruano-Ravina, Karl T Kelsey, Alberto Fernández-Villar, Juan M Barros-Dios
No abstract text is available yet for this article.
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29122918/recommending-prolonged-bedaquiline-use-for-the-treatment-of-highly-resistant-strains-of-tuberculosis
#15
LETTER
Jennifer Furin, Erica Lessem, Vivian Cox
No abstract text is available yet for this article.
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29122917/final-treatment-outcomes-of-multidrug-and-extensively-drug-resistant-tuberculosis-patients-in-latvia-receiving-delamanid-containing-regimens
#16
LETTER
Liga Kuksa, Linda Barkane, Norbert Hittel, Rajesh Gupta
No abstract text is available yet for this article.
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29122916/task-1-kcnk3-channels-in-the-lung-from-cell-biology-to-clinical-implications
#17
REVIEW
Andrea Olschewski, Emma L Veale, Bence M Nagy, Chandran Nagaraj, Grazyna Kwapiszewska, Fabrice Antigny, Mélanie Lambert, Marc Humbert, Gábor Czirják, Péter Enyedi, Alistair Mathie
TWIK-related acid-sensitive potassium channel 1 (TASK-1 encoded by KCNK3) belongs to the family of two-pore domain potassium channels. This gene subfamily is constitutively active at physiological resting membrane potentials in excitable cells, including smooth muscle cells, and has been particularly linked to the human pulmonary circulation. TASK-1 channels are sensitive to a wide array of physiological and pharmacological mediators that affect their activity such as unsaturated fatty acids, extracellular pH, hypoxia, anaesthetics and intracellular signalling pathways...
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29122915/elevated-lung-clearance-index-in-infants-with-cystic-fibrosis-shortly-after-birth
#18
Elisabeth Kieninger, Sophie Yammine, Insa Korten, Pinelopi Anagnostopoulou, Florian Singer, Urs Frey, Anne Mornand, Maura Zanolari, Isabelle Rochat, Daniel Trachsel, Dominik Mueller-Suter, Alexander Moeller, Carmen Casaulta, Philipp Latzin
It is not known at what age lung function impairment may arise in children with cystic fibrosis (CF). We assessed lung function shortly after birth in infants with CF diagnosed by newborn screening.We performed infant lung function measurements in a prospective cohort of infants with CF and healthy controls. We assessed lung clearance index (LCI), functional residual capacity (FRC) and tidal breathing parameters. The primary outcome was prevalence and severity of abnormal lung function (±1.64 z-scores) in CF...
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29122914/pulmonary-function-deficits-in-newborn-screened-infants-with-cystic-fibrosis-managed-with-standard-uk-care-are-mild-and-transient
#19
Gwyneth Davies, Janet Stocks, Lena P Thia, Ah-Fong Hoo, Andrew Bush, Paul Aurora, Lucy Brennan, Simon Lee, Sooky Lum, Philippa Cottam, Joanne Miles, Jane Chudleigh, Jane Kirkby, Ian M Balfour-Lynn, Siobhán B Carr, Colin Wallis, Hilary Wyatt, Angie Wade
With the advent of novel designer molecules for cystic fibrosis (CF) treatment, there is huge need for early-life clinical trial outcomes, such as infant lung function (ILF). We investigated the degree and tracking of ILF abnormality during the first 2 years of life in CF newborn screened infants.Forced expiratory volume in 0.5 s (FEV0.5), lung clearance index (LCI) and plethysmographic functional residual capacity were measured at ∼3 months, 1 year and 2 years in 62 infants with CF and 34 controls...
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29122913/infertility-in-an-adult-cohort-with-primary-ciliary-dyskinesia-phenotype-gene-association
#20
LETTER
Gert Jan Vanaken, Laurence Bassinet, Mieke Boon, Rahma Mani, Isabelle Honoré, Jean-Francois Papon, Harry Cuppens, Martine Jaspers, Natalie Laurent, André Coste, Estelle Escudier, Serge Amselem, Bernard Maitre, Marie Legendre, Sophie Christin-Maitre
No abstract text is available yet for this article.
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
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