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European Radiology

Julia Garayoa, Margarita Chevalier, Maria Castillo, Ignacio Mahillo-Fernández, Najim Amallal El Ouahabi, Carmen Estrada, Alejandro Tejerina, Olivia Benitez, Julio Valverde
OBJECTIVE: To demonstrate the non-inferiority of synthetic image (SI) mammography versus full-field digital mammography (FFDM) in breast tomosynthesis (DBT) examinations. METHODS: An observational, retrospective, single-centre, multireader blinded study was performed, using 2384 images to directly compare SI and FFDM based on Breast Imaging Reporting and Data System (BIRADS) categorisation and visibility of radiological findings. Readers had no access to digital breast tomosynthesis slices...
August 15, 2017: European Radiology
Minerva Becker, Arthur D Varoquaux, Christophe Combescure, Olivier Rager, Marc Pusztaszeri, Karim Burkhardt, Bénédicte M A Delattre, Pavel Dulguerov, Nicolas Dulguerov, Eirini Katirtzidou, Francesca Caparrotti, Osman Ratib, Habib Zaidi, Christoph D Becker
PURPOSE: To determine the diagnostic performance of FDG-PET/MRI with diffusion-weighted imaging (FDG-PET/DWIMRI) for detection and local staging of head and neck squamous cell carcinoma (HNSCC) after radio(chemo)therapy. MATERIALS AND METHODS: This was a prospective study that included 74 consecutive patients with previous radio(chemo)therapy for HNSCC and in whom tumour recurrence or radiation-induced complications were suspected clinically. The patients underwent hybrid PET/MRI examinations with morphological MRI, DWI and FDG-PET...
August 15, 2017: European Radiology
Bo Da Nam, Tae Jung Kim, Kyung Soo Lee, Tae Sung Kim, Joungho Han, Myung Jin Chung
PURPOSE: To evaluate serial computed tomography (CT) findings of pulmonary mucormycosis correlated with peripheral blood absolute neutrophil count (ANC). MATERIALS AND METHODS: Between February 1997 and June 2016, 20 immunocompromised patients (10 males, 10 females; mean age, 48.9 years) were histopathologically diagnosed as pulmonary mucormycosis. On initial (n=20) and follow-up (n=15) CT scans, the patterns of lung abnormalities and their changing features on follow-up scans were evaluated, and the pattern changes were correlated with ANC changes...
August 10, 2017: European Radiology
Davide Bellini, Domenico De Santis, Damiano Caruso, Marco Rengo, Riccardo Ferrari, Tommaso Biondi, Andrea Laghi
OBJECTIVES: To investigate whether diet restriction affects quality of colon cleansing and patient tolerance during reduced bowel preparation for CT colonography (CTC). METHODS: Asymptomatic and symptomatic patients were enrolled in this pragmatic, single-centre, randomised trial. All patients were randomly assigned (1:1 ratio, blocks of ten) to receive a reduced bowel preparation and faecal tagging with (Diet-Restriction-Group [DR]) or without (No-Diet-Restriction-Group [NDR]) dietary restriction...
August 10, 2017: European Radiology
Virgile Chevance, Thibaud Damy, Vania Tacher, François Legou, Fourat Ridouani, Alain Luciani, Hicham Kobeiter, Alain Rahmouni, Jean-François Deux
OBJECTIVE: To measure myocardium iodine concentration (MIC) in patients with cardiac amyloidosis (CA) using dual-energy computed tomography (DECT). METHODS: Twenty-two patients with CA, 13 with non-amyloid hypertrophic cardiomyopathies (CH) and 10 control patients were explored with pre-contrast, arterial and 5-minute DECT acquisition (Iomeprol; 1.5 mL/kg). Inter-ventricular septum (IVS) thickness, blood pool iodine concentration (BPIC), MIC (mg/mL), iodine ratio and extra-cellular volume (ECV) were calculated...
August 10, 2017: European Radiology
Jinrong Qu, Hongkai Zhang, Zhaoqi Wang, Fengguang Zhang, Hui Liu, Zhidan Ding, Yin Li, Jie Ma, Zhongxian Zhang, Shouning Zhang, Yafeng Dong, Lina Jiang, Wei Zhang, Robert Grimm, Berthold Kiefer, Ihab R Kamel, Jianjun Qin, Hailiang Li
OBJECTIVES: To compare the T staging of resectable oesophageal cancer (OC) using radial VIBE (r-VIBE) and endoscopic ultrasound (EUS) with pathological confirmation of the T stage. METHODS: Forty-three patients with endoscopically proven OC and indeterminate T1/T2/T3/T4a stage by computed tomography (CT) and EUS were imaged on a 3-T magnetic resonance imaging (MRI) scanner. T stage was scored on MRI and EUS by two independent radiologists and one endoscopist, respectively, and compared with postoperative pathological findings...
August 10, 2017: European Radiology
D Hausmann, N Aksöz, J von Hardenberg, T Martini, N Westhoff, S Buettner, S O Schoenberg, P Riffel
AIM: To evaluate the accuracy of a T2-weighted (T2w) - and a parallel transmit zoomed b = 2000 s/mm2 (b2000) - diffusion-weighted imaging sequence among three readers with different degrees of experience for prostate cancer (Pca) detection. METHODS: Ninety-three patients with suspected Pca were enrolled. For b2000 a two-dimensional spatially-selective RF pulse using an echo-planar transmit trajectory was applied, and the field of view (FOV) was reduced to one-third...
August 10, 2017: European Radiology
Yanfen Cui, Ran Luo, Ruifen Wang, Huanhuan Liu, Caiyuan Zhang, Zhongyang Zhang, Dengbin Wang
OBJECTIVES: To determine the diagnostic accuracy of conventional MRI in detecting tumour invasion of advanced intraocular retinoblastoma and to correlate ADC values with high-risk prognostic parameters. METHOD: The sensitivities, specificities, positive predictive values (PPV), negative predictive values (NPV) and accuracies of MRI in detecting tumour-extent parameters of 63 retinoblastomas were determined. Furthermore, ADC values were correlated with high-risk prognostic parameters...
August 7, 2017: European Radiology
Hyungjin Kim, Kum Ju Chae, Soon Ho Yoon, Miso Kim, Bhumsuk Keam, Tae Min Kim, Dong-Wan Kim, Jin Mo Goo, Chang Min Park
OBJECTIVES: To find predictors of non-diagnostic repeat biopsy specimen acquisition for mutational analysis and detection of epidermal growth factor receptor (EGFR) T790M mutation. METHODS: We retrospectively reviewed 90 non-small cell lung cancer patients harbouring EGFR mutations who underwent repeat cone-beam CT-guided transthoracic needle biopsy. Clinical characteristics as well as biopsy-related factors were compared between patients with and without diagnostic specimen acquisition and between patients with and without T790M mutation...
August 7, 2017: European Radiology
Juheon Lee, Yi Cui, Xiaoli Sun, Bailiang Li, Jia Wu, Dengwang Li, Michael F Gensheimer, Billy W Loo, Maximilian Diehn, Ruijiang Li
PURPOSE: To evaluate the prognostic value and molecular basis of a CT-derived pleural contact index (PCI) in early stage non-small cell lung cancer (NSCLC). EXPERIMENTAL DESIGN: We retrospectively analysed seven NSCLC cohorts. A quantitative PCI was defined on CT as the length of tumour-pleura interface normalised by tumour diameter. We evaluated the prognostic value of PCI in a discovery cohort (n = 117) and tested in an external cohort (n = 88) of stage I NSCLC...
August 7, 2017: European Radiology
Arthur J A T Braat, Jip F Prince, Rob van Rooij, Rutger C G Bruijnen, Maurice A A J van den Bosch, Marnix G E H Lam
OBJECTIVE: Radioembolisation is generally preceded by a scout dose of technetium-99m-macroaggregated albumin to estimate extrahepatic shunting of activity. Holmium-166 microspheres can be used as a scout dose (±250 MBq) and as a therapeutic dose. The general toxicity of a holmium-166 scout dose ((166)Ho-SD) and safety concerns of an accidental extrahepatic deposition of (166)Ho-SD were investigated. METHODS: All patients who received a (166)Ho-SD in our institute were reviewed for general toxicity and extrahepatic depositions...
August 7, 2017: European Radiology
Anne Becker, Max Masthoff, Jing Claussen, Steven James Ford, Wolfgang Roll, Matthias Burg, Peter J Barth, Walter Heindel, Michael Schäfers, Michel Eisenblätter, Moritz Wildgruber
BACKGROUND AND AIM: Multispectral optoacoustic tomography (MSOT) represents a new in vivo imaging technique with high resolution (~250 μm) and tissue penetration (>1 cm) using the photoacoustic effect. While ultrasound contains anatomical information for lesion detection, MSOT provides functional information based on intrinsic tissue chromophores. We aimed to evaluate the feasibility of combined ultrasound/MSOT imaging of breast cancer in patients compared to healthy volunteers...
August 7, 2017: European Radiology
Eun Sun Lee, Min Ju Kim, Sung Chan Park, Bo Yun Hur, Jong Hee Hyun, Hee Jin Chang, Ji Yeon Baek, Sun Young Kim, Dae Yong Kim, Jae Hwan Oh
OBJECTIVES: We evaluated the diagnostic performance of magnetic resonance imaging (MRI) in terms of identifying extramural venous invasion (EMVI) in rectal cancer patients with preoperative chemoradiotherapy (CRT) and its prognostic significance. METHODS: During 2008-2010, 200 patients underwent surgery following preoperative CRT for rectal cancer. Two radiologists independently reviewed all pre- and post-CRT MRI retrospectively. We investigated diagnostic performance of pre-CRT MR-EMVI (MR-EMVI) and post-CRT MR-EMVI (yMR-EMVI), based on pathological EMVI as the standard of reference...
August 7, 2017: European Radiology
Evangelia E Vassalou, Pavlos Katonis, Apostolos H Karantanas
OBJECTIVES: To increase the clinical awareness of piriformis muscle syndrome (PMs) by reporting cross-sectional imaging findings, the clinical impact of imaging studies and treatment outcome. METHODS: Within a 10-year-period, 116 patients referred for radiological evaluation of clinically suspected PMs, with excluded lumbar pathology related to symptomatology, were prospectively studied with MRI and/or computed tomography (CT). Piriformis muscle (PM), sciatic nerve (SN), piriformis region and sacroiliac joints were evaluated...
August 7, 2017: European Radiology
Dong Ho Lee, Se Hyung Kim, Ijin Joo, Joon Koo Han
OBJECTIVES: To prospectively evaluate if the perfusion parameters of gastric cancer can provide information on histologic subtypes of gastric cancer. METHODS: We performed preoperative perfusion CT (PCT) and curative gastrectomy in 46 patients. PCT data were analysed using a dedicated software program. Perfusion parameters were obtained by two independent radiologists and were compared according to histologic type using Kruskal-Wallis, Mann-Whitney U test and receiver operating characteristic analysis...
August 4, 2017: European Radiology
Hao Hu, Hong Han, Xi Kun Han, Wen Ping Wang, Hong Ding
OBJECTIVES: This study sought to develop a clinical nomogram for predicting post-hepatectomy liver failure (PHLF) among patients with resectable hepatocellular carcinoma (HCC). METHODS: The nomogram was established based on data obtained from a prospective study on 136 consecutive patients with resectable HCC undergoing hepatectomy from January 2015 to December 2015 in our centre. Another 80 patients in our centre served as an independent internal validation set...
August 4, 2017: European Radiology
Robert S Lim, Trevor A Flood, Matthew D F McInnes, Luke T Lavallee, Nicola Schieda
Renal angiomyolipomas without visible fat (AML.wovf) are benign masses that are incidentally discovered mainly in women. AML.wovf are typically homogeneously hyperdense on unenhanced CT without calcification or haemorrhage. Unenhanced CT pixel analysis is not useful for diagnosis. AML.wovf are characteristically homogeneously hypointense on T2-weighted (T2W)-MRI and apparent diffusion coefficient (ADC) maps. Despite early reports, only a minority of AML.wovf show signal intensity drop on chemical-shift MRI due to microscopic fat...
August 4, 2017: European Radiology
Jan-Carlo Janssen, Sebastian Meißner, Nadine Woythal, Vikas Prasad, Winfried Brenner, Gerd Diederichs, Bernd Hamm, Marcus R Makowski
PURPOSE: This study compared (68)Gallium-prostate-specific-membrane-antigen based Positron-emission-tomography ((68)Ga-PSMA-PET) and (99metastable)technetium-3,3-diphospho-1,2-propanedicarbonacid ((99m)Tc-DPD-SPECT) in performing skeletal staging in prostate cancer (PC) patients and evaluated the additional value of the information from low-dose-computed tomography (CT). MATERIALS AND METHODS: In this retrospective study, 54 patients who received (68)Ga-PSMA-PET/CT and (99m)Tc-DPD-SPECT/CT within 80 days were extracted from our database...
August 4, 2017: European Radiology
Anastasia Pomoni, Charalampos Sotiriadis, Frédérique Gay, Anne-Marie Jouannic, Salah D Qanadli
PURPOSE: To evaluate the efficacy and safety of percutaneous endovascular biopsy (PEB) in intravascular filling-defect lesions (IVLs) of the great vessels. MATERIAL AND METHODS: We retrospectively reviewed 19 patients (age 65 ± 12 years), 11 men and eight women, who underwent PEB for IVLs, between March 2004 and November 2014. All PEBs were performed for early diagnosis and/or characterization of the IVL, or in case of reasonable doubt about the IVL nature...
August 4, 2017: European Radiology
Akio Hiwatashi, Osamu Togao, Koji Yamashita, Kazufumi Kikuchi, Ryotaro Kamei, Hiroshi Yoshikawa, Atsushi Takemura, Hiroshi Honda
PURPOSE: To compare the abilities of turbo spin-echo diffusion-weighted imaging (TSE DWI) and multi-shot echo planar DWI (MSh DWI) to discriminate orbital lymphoma from inflammatory lesions. MATERIALS AND METHODS: Twenty-nine patients with pathologically confirmed lymphomas and 39 patients with inflammation were imaged with a 3.0-T system. The apparent diffusion coefficient (ADC) of each lesion was measured. Signal intensities compared to normal grey matter on conventional imaging were also measured...
August 4, 2017: European Radiology
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