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European Journal of Obstetrics, Gynecology, and Reproductive Biology

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https://www.readbyqxmd.com/read/30014930/association-betweengrem2-gene-polymorphism-with-osteoporosis-and-osteopenia-in-postmenopausal-women
#1
Adam Kamiński, Anna Bogacz, Izabela Uzar, Bogusław Czerny
OBJECTIVE: Osteoporosis is a civilization disease, in which the dominant symptoms are the loss of bone mass and disturbances in bone structure. Gremlin-2 is one of the BMP (bone morphogenetic proteins) antagonists and participate in osteogenesis and osteoblast differentiation. The aim of the study was to analyze whether the GREM2 gene polymorphism is significantly more common in postmenopausal women than in healthy women and whether it is a predisposing factor for the osteoporosis development...
July 9, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/30014929/in-vitro-probiotic-properties-of-vaginal-lactobacillus-fermentum-mg901-and-lactobacillus-plantarum-mg989-against-candida-albicans
#2
Chang-Ho Kang, YongGyeong Kim, Seul Hwa Han, Jin-Seong Kim, Nam-Soo Paek, Jae-Seong So
Candida albicans is the most important Candida species causing vulvovaginal candidiasis (VVC). We investigated the potential of the probiotic strains Lactobacillus fermentum MG901 and L. plantarum MG989 towards control of C. albiacns. Cell viability tests following co-culturing with lactobacilli revealed that C. albicans cells lost metabolic activity and were eventually killed. Further studies revealed that MG901 and MG989 had high surface hydrophobicity that enhanced its adhesion ability to epithelial cell...
July 9, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/30014931/body-fat-index-a-novel-alternative-to-body-mass-index-for-prediction-of-gestational-diabetes-and-hypertensive-disorders-in-pregnancy
#3
Ahmed A Nassr, Sherif A Shazly, Mari C Trinidad, Sherif A El-Nashar, Amber M Marroquin, Brian C Brost
OBJECTIVES: To evaluate the association of ultrasound measurement of maternal abdominal subcutaneous and pre-peritoneal fat thickness in relation to the subsequent diagnosis of gestational diabetes (GDM), and to assess the association of body fat index (BFI), compared to conventional body mass index (BMI), with respect to the development of some obstetric related complications. STUDY DESIGN: A prospective study included non-diabetic pregnant women who were scheduled for fetal anatomic survey...
July 6, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/30007250/effectiveness-of-an-antioxidant-preparation-with-n-acetyl-cysteine-alpha-lipoic-acid-and-bromelain-in-the-treatment-of-endometriosis-associated-pelvic-pain-leap-study
#4
Iñaki Lete, Nicolás Mendoza, Esther de la Viuda, Francisco Carmona
OBJECTIVE: To assess the impact of an antioxidant preparation with N-acetyl cysteine, alpha lipoic acid and bromelain on endometriosis-associated pelvic pain. STUDY DESIGN: Multicenter, open-label, non-comparative clinical trial in a representative sample of women with endometriosis-associated pelvic pain. RESULTS: In total, 398 patients with a mean age of 34.6 ± 7.2 years were treated with a combination of N-acetyl cysteine, alpha lipoic acid and bromelain for 6 months...
July 6, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/30007249/an-alternate-surgical-approach-to-reduce-hemorrhage-and-complications-during-cesarean-hysterectomy-for-adherent-placenta
#5
Pradip Kumar Saha, Rashmi Bagga, Jasvinder Kaur Kalra, Aashima Arora, Rimpi Singla, Vanita Suri, Kajal Jain, Praveen Kumar, Nalini Gupta, Ashish Jain, Tulika Singh, Ravimohan S Mavuduru
BACKGROUND: Cesarean hysterectomy for adherent placenta is associated with increased maternal morbidity due to massive hemorrhage requiring large volume blood transfusion, bladder or ureteric injury, intensive care unit (ICU) admission and prolonged hospital stay. There is an ongoing effort to improve the outcome of these women and measures to reduce blood loss. OBJECTIVE: The purpose of the present study was to develop an alternate surgical approach for performing a Cesarean hysterectomy in women with adherent placenta in order to reduce hemorrhage and urinary tract injuries, and thereby improve the maternal outcome...
July 4, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/30007247/maternal-concentrations-of-human-chorionic-gonadotropin-hcg-and-risk-for-cerebral-palsy-cp-in-the-child-a-case-control-study
#6
Anne Eskild, Lars Monkerud, Anne Marie Jukic, Bjørn Olav Åsvold, Kari Kveim Lie
BACKGROUND: Intrauterine conditions may be important in the development of cerebral palsy in the child. The hormone, human chorionic gonadotropin (hCG), is synthesized in the placenta, and hCG plays an important role in placental angiogenesis and development. Thus, maternal hCG concentrations may be an indicator of placental function and thereby the intrauterine environment for the offspring. We studied the associations of maternal concentrations of hCG during pregnancy with cerebral palsy in the child...
July 4, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29990827/what-women-want-results-from-a-prospective-multicenter-study-on-women-s-preference-about-pain-management-during-labour
#7
Alessandro Favilli, Antonio Simone Laganà, Ugo Indraccolo, Alessandra Righi, Onofrio Triolo, Maria D' Apolito, Sandro Gerli
OBJECTIVE: The aim of this study was to assess women preference about pain and duration of labour applying a standardized questionnaire. STUDY DESIGN: A prospective multicentre large cohort study was carried out in two different University Hospitals. A standardized questionnaire was proposed before active labour and the day after delivery in order to investigate whether women preferred low pain intensity for a longer labour duration or greater pain intensity for a shorter labour duration...
June 28, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29960200/vaginal-diazepam-plus-transcutaneous-electrical-nerve-stimulation-to-treat-vestibulodynia-a-randomized-controlled-trial
#8
Filippo Murina, Raffaele Felice, Stefania Di Francesco, Silvia Oneda
OBJECTIVE: To assess the effectiveness of vaginal diazepam in addition to transcutaneous electrical nerve stimulation (TENS) in the treatment of vestibulodynia (VBD). STUDY DESIGN: This study was a randomized, double-blind, placebo-controlled trial. Forty-two patients with VBD were randomized, 21 underwent diazepam and TENS (diazepam group) and 21 received placebo and TENS (placebo group). Vulvar pain was assessed on a on a 10-cm visual analogue scale (VAS) and dyspareunia according to the Marinoff dyspareunia scale...
June 26, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/30007248/the-use-of-o-ring-retractors-at-caesarean-section-a-systematic-review-and-meta-analysis
#9
G J Waring, S Shawer, K Hinshaw
O-ring retractors (Alexis/Mobius) have been shown to reduce the risk of Surgical site infection (SSI) following general abdominal surgery. The benefit at caesarean section (CS) remains to be established given the relatively high cost. OBJECTIVES: To assess the efficacy of O-ring retractors when used at CS. STUDY DESIGN: Systematic review and meta-analysis. Electronic databases were searched from inception of each database until January 2018. No language restrictions were applied...
June 25, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29957401/the-addition-of-growth-hormone-adjuvant-therapy-to-the-long-down-regulation-protocol-in-poor-responders-undergoing-in-vitro-fertilization-randomized-control-trial
#10
Dina M R Dakhly, Yasmin A Bassiouny, Yomna A Bayoumi, Mohamed A Hassan, Hisham M Gouda, Ayman A Hassan
OBJECTIVE: to detect the impact of growth hormone (GH) co-treatment to the long down regulation protocol, on the outcomes of IVF/ICSI cycles in poor responders. STUDY DESIGN: this parallel open label randomized control trial was conducted in a university hospital. It included 240 females satisfying the bologna criteria for poor responders. The enrolled females were randomized into 2 groups: A (long/GH) receiving GH adjuvant therapy to the long protocol and group B (control) receiving the long protocol alone...
June 22, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/30007246/the-use-of-p16-ki-67-dual-staining-technology-on-cervical-cytology-of-patients-undergoing-a-lletz-procedure
#11
Bram Packet, Willy Poppe, Birgit Weynand, Miet Vanherck
OBJECTIVES: The main objective of this prospective observational study was to investigate the diagnostic performance of the p16/Ki-67 dual stain technique (DST) for detecting CIN 2+ in a LLETZ referral setting. Test performances were compared with HR-HPV testing and Pap cytology. METHODS: All patients referred for a LLETZ procedure were candidates for participation in this trial. A total of 110 patients were enrolled between October 2016 and March 2017. From each participant, a cervical cytology sample was obtained before the onset of the LLETZ procedure...
June 21, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29957400/secondary-cytoreductive-surgery-viable-treatment-option-in-the-management-of-platinum-sensitive-recurrent-ovarian-cancer
#12
Michal Felsinger, Lubos Minar, Vit Weinberger, Ivo Rovny, Filip Zlamal, Julie Bienertova-Vasku
OBJECTIVE: This study aimed to evaluate the impact of the secondary cytoreductive surgery on survival parameters in women with platinum-sensitive recurrent ovarian cancer who undergone secondary cytoreduction following chemotherapy compared to women who recieved chemotherapy alone. STUDY DESIGN: In a retrospective study, data were rewieved from women who were diagnosed and treated with ovarian cancer and its primary platinum-sensitive recurrence at the University Hospital Brno in the Czech Republic between November 2009 and March 2016...
June 20, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29980113/vanishing-gastroschisis-visualized-by-antenatal-ultrasound-a-case-report-and-review-of-literature
#13
REVIEW
Milagros Marin Ponce, Dominique Hermans, Catherine de Magnee, Corinne Hubinont, Jean-Marc Biard
We report a case of vanishing gastroschisis visualized by antenatal ultrasound with a 7-year long term follow-up. Currently, the child is still dependent on daily parenteral nutrition with no signs of hepatotoxicity. To our knowledge, it's the fourth case with a long-term follow-up. Vanishing gastroschisis is a rare complication of gastroschisis. However, physicians should be aware of it because its prognosis is worse than classical gastroschisis. When a vanishing gastroschisis is visualized or suspected by antenatal ultrasound, prenatal counseling is required with explanations about the risk of short bowel syndrome, the need of parenteral nutrition and related complications (inflammatory colitis, sepsis, liver failure and organ transplant)...
June 19, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29980112/risk-factors-analysis-and-a-scoring-system-proposal-for-the-prediction-of-retained-placenta-after-vaginal-delivery
#14
Alessandro Favilli, Valentina Tosto, Margherita Ceccobelli, Vittorio Bini, Sandro Gerli
INTRODUCTION: Retained placenta (RP) is an obstetric complication of third stage of labour. We aimed to evaluate risk factors for RP and to propose a scoring system in order to predict this potentially fatal disorder. METHODS: This was a retrospective case-control study, comparing women with RP after vaginal delivery (≥ 24 weeks of gestation) and women with regular placental separation. Data were collected from January 2007 to October 2017, in two 2nd level University Hospitals...
June 19, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29980111/trichomonas-vaginalis-infection-associated-risk-of-cervical-cancer-a-meta-analysis
#15
Shaoyan Yang, Weidong Zhao, Huiyan Wang, Yun Wang, Jie Li, Xiao Wu
Trichomoniasis, caused by the extracellular eukaryotic parasite trichomonas vaginalis, is one of the most common non-viral sexually transmitted infections worldwide. The correlation between trichomoniasis and cervical cancer was ambiguous. This meta-analysis was carried out to determine the relevance between trichomoniasis and cervical cancer. Relevant data from 1985 to 2016 were identified through an extensive search of Medline, Cochrane database, Google Scholar, EMBASE, China National Knowledge Infrastructure...
June 19, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29960201/a-study-of-treatments-and-outcomes-in-elderly-women-with-cervical-cancer
#16
Kumi Shimamoto, Toshiaki Saito, Shoko Kitade, Yui Tomita, Rina Nagayama, Shinichiro Yamaguchi, Kazuya Ariyoshi, Masao Okadome
OBJECTIVE: With the population aging, development of safe and effective treatments for elderly patients with cancer is needed. Although old age is considered a poor prognostic factor, this is not only because of the patient's disease condition or response to treatment, but also because of treatment strategy and intensity. The purpose of this study was to clarify the influence of age on treatment and prognosis in patients with cervical cancer. METHODS: Women with stage Ib-IV cervical cancer treated at our institution between 1997 and 2014 were retrospectively analyzed...
June 18, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29940417/development-and-internal-validation-of-a-clinical-prediction-model-for-external-cephalic-version
#17
Joost Velzel, Ewoud Schuit, Floortje Vlemmix, Jan F M Molkenboer, Joris A M Van der Post, Ben W Mol, Marjolein Kok
OBJECTIVE: To develop a prediction model for the chance of successful external cephalic version (ECV). STUDY DESIGN: This is a secondary analysis of a multicenter, open-label randomized controlled trial that assessed the effectiveness of atosiban compared to fenoterol as uterine relaxant during ECV in women with a singleton fetus in breech presentation with a gestational age of 36 weeks or more. Potential predictors included maternal, pregnancy, fetal, and treatment characteristics and were recorded in all participants...
June 18, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29937204/guillain-barr%C3%A3-syndrome-in-pregnancy-successful-multidisciplinary-approach
#18
LETTER
L S Kasaven, C Basu
No abstract text is available yet for this article.
June 18, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29936400/age-menopausal-status-and-the-bladder-microbiome
#19
Natasha Curtiss, Aswini Balachandran, Louise Krska, Claire Peppiatt-Wildman, Scott Wildman, Jonathan Duckett
OBJECTIVES: The bladder is not sterile but contains a healthy community of microbes termed the microbiome. Alterations in the bladder microbiome have been demonstrated in disease states such as the overactive bladder. The microbiome in other anatomical niches is known to alter with age eg the vagina. The objective of this study was to identify if the bladder microbiome in healthy women varies with age and menopausal status. STUDY DESIGN: Urine from 79 healthy women attending secondary care gynaecological clinics with no urinary symptoms provided clean catch mid-stream urine specimens...
June 18, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29933195/bioelectrical-impedance-analysis-a-new-method-to-evaluate-lymphoedema-fluid-status-and-tissue-damage-after-gynaecological-surgery-a-systematic-review
#20
REVIEW
Madeleine Asklöf, Preben Kjølhede, Ninnie Borendal Wodlin, Lena Nilsson
The aim of this descriptive review is to summarise the current knowledge of non-invasive bioelectrical impedance analysis (BIA) used with gynaecological surgical patients in regard to postoperative development of lymphoedema and determination of perioperative fluid balance, and as a prognostic factor in cancer mortality and a predictor of postoperative complications. The databases PubMed, MEDLINE, Scopus Web of Science, the Cochrane Library, and reference lists of selected articles were searched for relevant articles published during the period January 2008-April 2018...
June 18, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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