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European Journal of Nuclear Medicine and Molecular Imaging

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https://www.readbyqxmd.com/read/30315321/correction-to-highlights-from-2017-impactful-topics-published-in-the-annals-of-nuclear-medicine
#1
Andrea Farolfi, Pietro Ghedini, Stefano Fanti
The author names in the original version of this article were inversed. Correct author names were reflected here.
October 12, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30310953/value-proposition-of-psma-targeted-%C3%AE-particle-radioligand-therapy-in-metastatic-prostate-cancer
#2
EDITORIAL
Hossein Jadvar
No abstract text is available yet for this article.
October 11, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30310952/christopher-e-comstock-christiane-kuhl-eds-abbreviated-mri-of-the-breast-a-practical-guide-thieme-medical-publishers-inc-2018-isbn-978-1-62623-193-1
#3
Luigi Mansi
No abstract text is available yet for this article.
October 11, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30302506/target-identification-for-the-diagnosis-and-intervention-of-vulnerable-atherosclerotic-plaques-beyond-18-f-fluorodeoxyglucose-positron-emission-tomography-imaging-promising-tracers-on-the-horizon
#4
Jan Bucerius, Ingrid Dijkgraaf, Felix M Mottaghy, Leon J Schurgers
Cardiovascular disease is the major cause of morbidity and mortality in developed countries and atherosclerosis is the major cause of cardiovascular disease. Atherosclerotic lesions obstruct blood flow in the arterial vessel wall and can rupture leading to the formation of occlusive thrombi. Conventional diagnostic tools are still of limited value for identifying the vulnerable arterial plaque and for predicting its risk of rupture and of releasing thromboembolic material. Knowledge of the molecular and biological processes implicated in the process of atherosclerosis will advance the development of imaging probes to differentiate the vulnerable plaque...
October 9, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30298378/i-131-as-adjuvant-treatment-for-differentiated-thyroid-carcinoma-may-cause-an-increase-in-the-incidence-of-secondary-haematological-malignancies-an-inconvenient-truth
#5
EDITORIAL
Frederik A Verburg, Luca Giovanella, Ioannis Iakovou, Mark W Konijnenberg, Werner Langsteger, Michael Lassmann, Jasna Mihailovic, Markus Luster
No abstract text is available yet for this article.
October 8, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30291374/metabotropic-glutamate-receptor-subtype-5-is-altered-in-lps-induced-murine-neuroinflammation-model-and-in-the-brains-of-ad-and-als-patients
#6
Adrienne Müller Herde, Roger Schibli, Markus Weber, Simon M Ametamey
PURPOSE: The aim of the present study was to determine the expression levels of mGluR5 in different mouse strains after induction of neuroinflammation by lipopolysaccharide (LPS) challenge and in the brains of patients with Alzheimer's disease (AD) and amyotrophic lateral sclerosis (ALS) post mortem to investigate mGluR5 expression in human neurodegenerative diseases. METHODS: C57BL/6 and CD1 mice were injected intraperitoneally with either 10 mg/kg LPS or saline...
October 5, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30291373/fdg-pet-ct-for-assessing-tumour-response-to-immunotherapy-report-on-the-eanm-symposium-on-immune-modulation-and-recent-review-of-the-literature
#7
REVIEW
Nicolas Aide, Rodney J Hicks, Christophe Le Tourneau, Stéphanie Lheureux, Stefano Fanti, Egesta Lopci
This paper follows the immunotherapy symposium held during the European Association of Nuclear Medicine (EANM) 2017 Annual Congress. The biological basis of the immune checkpoint inhibitors and the drugs most frequently used for the treatment of solid tumours are reviewed. The issues of pseudoprogression (frequency, timeline), hyperprogression and immune-related side effects are discussed, as well as their implications for patient management. A review of the recent literature on the use of FDG PET for assessment of immunotherapy is presented, and recommendations are provided for assessing tumour response and reporting immune-related side effects with FDG PET based on published data and experts' experience...
October 5, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30288547/william-t-o-brien-sr-top-3-differentials-in-radiology-a-case-review-second-edition-thieme-medical-publishers-inc-2018-isbn-9781626232785
#8
Luigi Mansi
No abstract text is available yet for this article.
October 4, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30276440/feasibility-of-multi-parametric-pet-and-mri-for-prediction-of-tumour-recurrence-in-patients-with-glioblastoma
#9
Michael Lundemann, Per Munck Af Rosenschöld, Aida Muhic, Vibeke A Larsen, Hans S Poulsen, Svend-Aage Engelholm, Flemming L Andersen, Andreas Kjær, Henrik B W Larsson, Ian Law, Adam E Hansen
BACKGROUND: Recurrence in glioblastoma patients often occur close to the original tumour and indicates that the current treatment is inadequate for local tumour control. In this study, we explored the feasibility of using multi-modality imaging at the time of radiotherapy planning. Specifically, we aimed to identify parameters from pre-treatment PET and MRI with potential to predict tumour recurrence. MATERIALS AND METHODS: Sixteen patients were prospectively recruited and treated according to established guidelines...
October 2, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30276439/naf-uptake-in-unstable-plaque-what-does-fluoride-uptake-mean
#10
EDITORIAL
Takehiro Nakahara, Jagat Narula, H William Strauss
No abstract text is available yet for this article.
October 2, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30276438/prognostic-role-of-baseline-18f-fdg-pet-ct-metabolic-parameters-in-burkitt-lymphoma
#11
Domenico Albano, Giovanni Bosio, Chiara Pagani, Alessandro Re, Alessandra Tucci, Raffaele Giubbini, Francesco Bertagna
PURPOSE: Burkitt's lymphoma (BL) is an aggressive lymphoma subtype with high 18F-FDG avidity at 18F-FDG-PET/CT, but no validated criteria for PET/CT in treatment evaluation or prediction of outcome in BL are available. The aim of our study was to investigate whether the metabolic baseline PET/CT parameters can predict treatment response and prognosis in BL. MATERIALS AND METHODS: We retrospectively enrolled 65 patients who underwent baseline 18F-FDG-PET/CT, interim and end of treatment PET/CT...
October 2, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30270409/pet-imaging-of-11-c-pbr28-in-parkinson-s-disease-patients-does-not-indicate-increased-binding-to-tspo-despite-reduced-dopamine-transporter-binding
#12
Katarina Varnäs, Zsolt Cselényi, Aurelija Jucaite, Christer Halldin, Per Svenningsson, Lars Farde, Andrea Varrone
PURPOSE: To examine the hypothesis that cerebral binding to the 18 kDa translocator protein (TSPO), a marker of microglia activation, is elevated in Parkinson's disease (PD), and to assess the relationship between brain TSPO binding and dopaminergic pathology in PD. METHODS: The radioligand [11 C]PBR28 was used for quantitative assessment of brain TSPO in 16 control subjects and 16 PD patients. To analyse the relationship between dopaminergic pathology and brain TSPO binding, PET studies of the dopamine transporter (DAT) were undertaken in PD patients using the DAT radioligand [18 F]FE-PE2I...
October 1, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30269157/nicotinic-receptor-abnormalities-as-a-biomarker-in-idiopathic-generalized-epilepsy
#13
Valentina Garibotto, Michael Wissmeyer, Zoi Giavri, Rachel Goldstein, Yann Seimbille, Margitta Seeck, Osman Ratib, Sven Haller, Fabienne Picard
PURPOSE: Mutations of cholinergic neuronal nicotinic receptors have been identified in the autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE), associated with changes on PET images using [18 F]-F-85380-A (F-A-85380), an α4β2 nicotinic receptor ligand. The aim of the present study was to evaluate potential changes in nicotinic receptor availability in other types of epilepsy. METHODS: We included 34 male participants, 12 patients with idiopathic generalized epilepsy (IGE), 10 with non-lesional diurnal focal epilepsy, and 12 age-matched healthy controls...
September 29, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30269156/the-renaissance-of-functional-18-f-fdg-pet-brain-activation-imaging
#14
EDITORIAL
Antoine Verger, Eric Guedj
No abstract text is available yet for this article.
September 29, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30269155/practice-based-evidence-for-the-clinical-benefit-of-pet-ct-results-of-the-first-oncologic-pet-ct-registry-in-germany
#15
Christina Pfannenberg, Brigitte Gueckel, Lisa Wang, Sergios Gatidis, Susann-Cathrin Olthof, Werner Vach, Matthias Reimold, Christian la Fougere, Konstantin Nikolaou, Peter Martus
PURPOSE: The purpose of this study was to evaluate the impact of PET/CT on clinical management of cancer patients based on a prospective data registry. The study was developed to inform consultations with public health insurances on PET/CT coverage. METHODS: We evaluated a prospective patient cohort having a clinically indicated PET/CT at a single German University Center from April 2013 to August 2016. The registry collected questionnaire data from requesting physicians on intended patient management before and after PET/CT...
September 29, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30269154/dynamic-whole-body-pet-imaging-principles-potentials-and-applications
#16
REVIEW
Arman Rahmim, Martin A Lodge, Nicolas A Karakatsanis, Vladimir Y Panin, Yun Zhou, Alan McMillan, Steve Cho, Habib Zaidi, Michael E Casey, Richard L Wahl
PURPOSE: In this article, we discuss dynamic whole-body (DWB) positron emission tomography (PET) as an imaging tool with significant clinical potential, in relation to conventional standard uptake value (SUV) imaging. BACKGROUND: DWB PET involves dynamic data acquisition over an extended axial range, capturing tracer kinetic information that is not available with conventional static acquisition protocols. The method can be performed within reasonable clinical imaging times, and enables generation of multiple types of PET images with complementary information in a single imaging session...
September 29, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30267117/salvage-extended-field-or-involved-field-nodal-irradiation-in-18-f-fluorocholine-pet-ct-oligorecurrent-nodal-failures-from-prostate-cancer
#17
Alexis Lépinoy, Yannick E Silva, Etienne Martin, Aurélie Bertaut, Magali Quivrin, Léone Aubignac, Alexandre Cochet, Gilles Créhange
PURPOSE: The concept of metastasis-directed therapy for nodal oligorecurrences with stereotactic body radiotherapy is increasingly accepted. Hence, the comparison between salvage extended field radiotherapy (s-EFRT) and salvage involved field radiotherapy (s-IFRT) in patients with 18 F-fluorocholine (FCH) PET/CT+ nodal oligorecurrences from prostate cancer is worthy of investigation. METHODS: Patients with oligorecurrent nodes on FCH PET/CT treated with salvage radiotherapy between 2009 and 2017 in a single tertiary cancer centre were selected for this study...
September 28, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30267116/salvage-peptide-receptor-radionuclide-therapy-with-177-lu-dota-tyr-3-octreotate-in-patients-with-bronchial-and-gastroenteropancreatic-neuroendocrine-tumours
#18
W A van der Zwan, T Brabander, B L R Kam, J J M Teunissen, R A Feelders, J Hofland, E P Krenning, W W de Herder
PURPOSE: Therapy with [177 Lu-DOTA,Tyr3 ]octreotate is effective in patients with grade I/II metastasized and/or inoperable bronchial neuroendocrine tumour (NET) or gastroenteropancreatic NET (GEP-NET). In this study, we investigated the efficacy and safety of salvage treatment with [177 Lu-DOTA,Tyr3 ]octreotate. METHODS: Patients with progressive bronchial NET or GEP-NET were selected for re-(re)treatment if they had benefited from initial peptide receptor radionuclide therapy (I-PRRT) with a minimal progression-free survival (PFS) of 18 months...
September 28, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30267115/highlights-from-2017-impactful-topics-published-in-the-annals-of-nuclear-medicine
#19
REVIEW
Andrea Farolfi, Pietro Ghedini, Stefano Fanti
The aim of the review is to highlight articles published in 2017 in the Annals of Nuclear Medicine, an official peer-reviewed journal of the Japanese Society of Nuclear Medicine. Among all published manuscripts during the past year, we conducted a subjective selection of the most relevant topics. Fourteen fascinating articles are included in this review, ranging in topic from preclinical to clinical arenas.
September 28, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30264225/value-of-early-evaluation-of-treatment-response-using-18-f-fdg-pet-ct-parameters-and-the-epstein-barr-virus-dna-load-for-prediction-of-outcome-in-patients-with-primary-nasopharyngeal-carcinoma
#20
Yu-Hung Chen, Kai-Ping Chang, Sung-Chao Chu, Tzu-Chen Yen, Ling-Yi Wang, Joseph Tung-Chieh Chang, Cheng-Lung Hsu, Shu-Hang Ng, Shu-Hsin Liu, Sheng-Chieh Chan
PURPOSE: To determine the value of early evaluation of response to concurrent chemoradiotherapy (CCRT) using 18 F-FDG PET-derived parameters and the Epstein-Barr virus (EBV) DNA titre in outcome prediction in patients with primary nasopharyngeal carcinoma (NPC). METHODS: Sixty patients with primary NPC were prospectively enrolled. All patients underwent 18 F-FDG PET/CT before and during CCRT. The plasma EBV DNA titre was measured along with the PET/CT-derived parameters...
September 27, 2018: European Journal of Nuclear Medicine and Molecular Imaging
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