journal
https://read.qxmd.com/read/38380954/continuous-glucose-monitoring-based-metrics-and-hypoglycemia-duration-in-insulin-experienced-individuals-with-long-standing-type-2-diabetes-switched-from-a-daily-basal-insulin-to-once-weekly-insulin-icodec-post-hoc-analysis-of-onwards-2-and-onwards-4
#21
JOURNAL ARTICLE
Harpreet S Bajaj, Björg Ásbjörnsdóttir, Lisbeth Carstensen, Christian Laugesen, Chantal Mathieu, Athena Philis-Tsimikas, Tadej Battelino
OBJECTIVE: This post hoc analysis assessed continuous glucose monitoring (CGM)-based metrics and hypoglycemia duration with once-weekly insulin icodec versus once-daily basal insulin analogs in insulin-experienced individuals with long-standing type 2 diabetes from two 26-week phase 3a trials (ONWARDS 2 and ONWARDS 4). RESEARCH DESIGN AND METHODS: Time in range (TIR) (3.9-10.0 mmol/L), time above range (TAR) (>10.0 mmol/L), and time below range (TBR) (<3.9 mmol/L and <3...
February 21, 2024: Diabetes Care
https://read.qxmd.com/read/38377531/identifying-preferred-features-of-weight-loss-programs-for-adults-with-or-at-risk-of-type-2-diabetes-a-discrete-choice-experiment-with-3-960-adults-in-the-u-k
#22
JOURNAL ARTICLE
John Buckell, Caroline A Mitchell, Kate Fryer, Carolyn Newbert, Alan Brennan, Jack Joyce, Susan A Jebb, Paul Aveyard, Nicola Guess, Elizabeth Morris
OBJECTIVE: To understand preferences for features of weight loss programs among adults with or at risk of type 2 diabetes in the U.K. RESEARCH DESIGN AND METHODS: We conducted a discrete choice experiment with 3,960 U.K. adults living with overweight (n = 675 with type 2 diabetes). Preferences for seven characteristics of weight loss programs were analyzed. Simulations from choice models using the experimental data predicted uptake of available weight loss programs...
February 20, 2024: Diabetes Care
https://read.qxmd.com/read/38377492/disparities-in-sodium-glucose-cotransporter-2-sglt2-inhibitors-prescription-and-dispensing-in-the-israeli-population-a-retrospective-cohort-study
#23
JOURNAL ARTICLE
Yaara Leibovici Weissman, Bronislava Calvarysky, Tzippy Shochat, Zoya Korotkov, Alon Grossman, Leonard Leibovici, Adi Turjeman
OBJECTIVE: To describe disparities in prescribing and dispensing sodium-glucose cotransporter 2 inhibitors (SGLT2i) in Israel. RESEARCH DESIGN AND METHODS: This was a population-based retrospective cohort study of adults with type 2 diabetes eligible for SGLT2i treatment from 2017 to 2023. The primary outcome was the time between initial eligibility and the first prescription of SGLT2i. RESULTS: Among 32,742 eligible patients, only 53% were prescribed SGLT2i...
February 20, 2024: Diabetes Care
https://read.qxmd.com/read/38377484/lifetime-duration-of-breastfeeding-and-cardiovascular-risk-in-women-with-type-2-diabetes-or-a-history-of-gestational-diabetes-findings-from-two-large-prospective-cohorts
#24
JOURNAL ARTICLE
Anna Birukov, Marta Guasch-Ferré, Sylvia H Ley, Deirdre K Tobias, Fenglei Wang, Clemens Wittenbecher, Jiaxi Yang, JoAnn E Manson, Jorge E Chavarro, Frank B Hu, Cuilin Zhang
OBJECTIVE: Breastfeeding duration is inversely associated with risks of cardiovascular disease (CVD) and type 2 diabetes in parous women. However, the association among women at high risk, including women with type 2 diabetes or gestational diabetes (GDM) is unclear. RESEARCH DESIGN AND METHODS: We included 15,146 parous women with type 2 diabetes from the Nurses' Health Study I and II (NHS, NHS II) and 4,537 women with a history of GDM from NHS II. Participants reported history of breastfeeding via follow-up questionnaires...
February 20, 2024: Diabetes Care
https://read.qxmd.com/read/38363973/prevalence-and-predictive-factors-for-celiac-disease-in-children-with-type-1-diabetes-whom-and-when-to-screen-a-nationwide-longitudinal-cohort-study-of-swedish-children
#25
JOURNAL ARTICLE
Marie Lindgren, Fredrik Norström, Martina Persson, Helena Elding Larsson, Gun Forsander, Karin Åkesson, Ulf Samuelsson, Johnny Ludvigsson, Annelie Carlsson
OBJECTIVE: To examine the prevalence and predictive factors for celiac disease (CD) after a diagnosis of type 1 diabetes (T1D) in children and adolescents, to improve the current screening guidelines. RESEARCH DESIGN AND METHODS: The association between sex, age at T1D diagnosis, HLA, and diabetes autoantibodies, and a diagnosis of CD was examined in 5,295 children with T1D from the Better Diabetes Diagnosis study in Sweden. RESULTS: The prevalence of biopsy-proven CD was 9...
February 16, 2024: Diabetes Care
https://read.qxmd.com/read/38363873/risk-of-anaphylaxis-among-new-users-of-glp-1-receptor-agonists-a-cohort-study
#26
JOURNAL ARTICLE
Mary S Anthony, Vanita R Aroda, Lauren E Parlett, Leila Djebarri, Sofia Berreghis, Brian Calingaert, Daniel C Beachler, Christopher L Crowe, Catherine B Johannes, Juhaeri Juhaeri, Stephan Lanes, Chunshen Pan, Kenneth J Rothman, Catherine W Saltus, Kathleen E Walsh
OBJECTIVE: To assess risk of anaphylaxis among patients with type 2 diabetes mellitus who are initiating therapy with a glucagon-like peptide-1 receptor agonist (GLP-1 RA), with a focus on those starting lixisenatide therapy. RESEARCH DESIGN AND METHODS: A cohort study was conducted in three large, U.S. claims databases (2017-2021). Adult (aged ≥18 years) new users of a GLP-1 RA who had type 2 diabetes mellitus and ≥6 months enrollment in the database before GLP-1 RA initiation (start of follow-up) were included...
February 16, 2024: Diabetes Care
https://read.qxmd.com/read/38349856/plant-based-dietary-patterns-and-incident-diabetes-in-the-atherosclerosis-risk-in-communities-aric-study
#27
JOURNAL ARTICLE
Valerie K Sullivan, Hyunju Kim, Laura E Caulfield, Lyn M Steffen, Elizabeth Selvin, Casey M Rebholz
OBJECTIVE: Plant-based dietary patterns emphasize plant foods and minimize animal-derived foods. We investigated the association between plant-based dietary patterns and diabetes in a community-based U.S. sample of Black and White adults. RESEARCH DESIGN AND METHODS: We included middle-aged adults from the Atherosclerosis Risk in Communities (ARIC) study without diabetes at baseline who completed a food-frequency questionnaire (n = 11,965). We scored plant-based diet adherence according to three indices: overall, healthy, and unhealthy plant-based diet indices...
February 13, 2024: Diabetes Care
https://read.qxmd.com/read/38335226/erratum-diabetes-in-south-asians-uncovering-novel-risk-factors-with-longitudinal-epidemiologic-data-kelly-west-award-lecture-2023-diabetes-care-2024-47-7-16
#28
Alka M Kanaya
In the article cited above, Fig. 1 contained a mistake for the map of India. The correct image is shown below. The author apologizes for the error. The online version of the article (https://doi.org/10.2337/dci23-0068) has been updated with the correct image.
February 9, 2024: Diabetes Care
https://read.qxmd.com/read/38329838/atypical-diabetes-what-have-we-learned-and-what-does-the-future-hold
#29
JOURNAL ARTICLE
Stephen I Stone, Ashok Balasubramanyam, Jennifer E Posey
As our understanding of the pathophysiology of diabetes evolves, we increasingly recognize that many patients may have a form of diabetes that does not neatly fit with a diagnosis of either type 1 or type 2 diabetes. The discovery and description of these forms of "atypical diabetes" have led to major contributions to our collective understanding of the basic biology that drives insulin secretion, insulin resistance, and islet autoimmunity. These discoveries now pave the way to a better classification of diabetes based on distinct endotypes...
February 8, 2024: Diabetes Care
https://read.qxmd.com/read/38329795/epidemiology-and-prognostic-implications-of-coronary-artery-calcium-in-asymptomatic-individuals-with-prediabetes-a-multicohort-study
#30
JOURNAL ARTICLE
Mahmoud Al Rifai, Mouaz H Al-Mallah, Michael J Blaha, Jaideep Patel, John W McEvoy, Khurram Nasir, Izza Shahid, Kershaw V Patel, Garima Sharma, Jaume Marrugat, Helena Tizon-Marcos, Raimund Erbel, Andreas Stang, Karl-Heinz Jöckel, Nils Lehmann, Sara Schramm, Börge Schmidt, Roger S Blumenthal, Salim S Virani, Vijay Nambi, Miguel Cainzos-Achirica
OBJECTIVE: To describe the epidemiology and prognostic value of coronary artery calcium (CAC) in individuals with prediabetes. RESEARCH DESIGN AND METHODS: We pooled participants free of clinical atherosclerotic cardiovascular disease (ASCVD) from four prospective cohorts: the Multi-Ethnic Study of Atherosclerosis, Heinz Nixdorf Recall Study, Framingham Heart Study, and Jackson Heart Study. Two definitions were used for prediabetes: inclusive (fasting plasma glucose [FPG] ≥100 to <126 mg/dL and hemoglobin A1c [HbA1c] ≥5...
February 8, 2024: Diabetes Care
https://read.qxmd.com/read/38324670/improved-glycemic-outcomes-with-diabetes-technology-use-independent-of-socioeconomic-status-in-youth-with-type-1-diabetes
#31
JOURNAL ARTICLE
Kate E Lomax, Craig E Taplin, Mary B Abraham, Grant J Smith, Aveni Haynes, Ella Zomer, Katrina L Ellis, Helen Clapin, Sophia Zoungas, Alicia J Jenkins, Jennifer Harrington, Martin I de Bock, Timothy W Jones, Elizabeth A Davis
OBJECTIVE: Technology use in type 1 diabetes (T1D) is impacted by socioeconomic status (SES). This analysis explored relationships between SES, glycemic outcomes, and technology use. RESEARCH DESIGN AND METHODS: A cross-sectional analysis of HbA1c data from 2,822 Australian youth with T1D was undertaken. Residential postcodes were used to assign SES based on the Index of Relative Socio-Economic Disadvantage (IRSD). Linear regression models were used to evaluate associations among IRSD quintile, HbA1c, and management regimen...
February 7, 2024: Diabetes Care
https://read.qxmd.com/read/38320264/longitudinal-changes-in-sex-hormone-binding-globulin-shbg-and-risk-of-incident-diabetes-the-study-of-women-s-health-across-the-nation-swan
#32
JOURNAL ARTICLE
Monique M Hedderson, Angela Capra, Catherine Lee, Laurel A Habel, Jennifer Lee, Ellen B Gold, Sylvia E Badon, Susanna D Mitro, Samar R El Khoudary
OBJECTIVE: To investigate the associations of longitudinal changes in sex hormone binding globulin (SHBG) and testosterone (T) over the menopause transition with the risk of diabetes. RESEARCH DESIGN AND METHODS: We followed 2,952 participants in the Study of Women's Health Across the Nation (SWAN) who were premenopausal or early perimenopausal and diabetes-free at baseline. SHBG,T, and estradiol (E2) levels were measured at up to 13 follow-up visits (over up to 17 years)...
February 6, 2024: Diabetes Care
https://read.qxmd.com/read/38315188/erratum-5-facilitating-positive-health-behaviors-and-well-being-to-improve-health-outcomes-standards-of-care-in-diabetes-2024-diabetes-care-2024-47-suppl-1-s77-s110
#33
(no author information available yet)
In the article cited above, the content regarding the times to evaluate the need for diabetes self-management education (DSMES) has been reworded for better clarity. The original Recommendation 5.2 appeared as follows: "There are five critical times to evaluate the need for DSMES to promote skills acquisition to aid treatment plan implementation, medical nutrition therapy, and well-being: at diagnosis, when not meeting treatment goals, annually, when complicating factors develop (medical, physical, and psychosocial), and when transitions in life and care occur...
February 5, 2024: Diabetes Care
https://read.qxmd.com/read/38305782/demographic-clinical-management-and-outcome-characteristics-of-8-004-young-children-with-type-1-diabetes
#34
JOURNAL ARTICLE
Jessica L Sandy, Sascha R Tittel, Saketh Rompicherla, Beate Karges, Steven James, Nicole Rioles, Anthony G Zimmerman, Elke Fröhlich-Reiterer, David M Maahs, Stefanie Lanzinger, Maria E Craig, Osagie Ebekozien
OBJECTIVE: To compare demographic, clinical, and therapeutic characteristics of children with type 1 diabetes age <6 years across three international registries: Diabetes Prospective Follow-Up Registry (DPV; Europe), T1D Exchange Quality Improvement Network (T1DX-QI; U.S.), and Australasian Diabetes Data Network (ADDN; Australasia). RESEARCH DESIGN AND METHODS: An analysis was conducted comparing 2019-2021 prospective registry data from 8,004 children. RESULTS: Mean ± SD ages at diabetes diagnosis were 3...
February 2, 2024: Diabetes Care
https://read.qxmd.com/read/38300898/the-efficacy-and-safety-of-glucagon-like-peptide-1-agonists-in-a-retrospective-study-of-patients-with-familial-partial-lipodystrophy
#35
JOURNAL ARTICLE
Maria C Foss-Freitas, Salman Imam, Adam Neidert, Anabela Dill Gomes, David T Broome, Elif A Oral
OBJECTIVE: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely used for the management of diabetes mellitus (DM), but their efficacy in familial partial lipodystrophy (FPLD) is unknown. In this retrospective study, we evaluated the effect of GLP-1RA in patients with FPLD. RESEARCH DESIGN AND METHODS: We analyzed data, reported with SDs, from 14 patients with FPLD (aged 58 ± 12 years; 76.47% female) and 14 patients with type 2 DM (aged 58 ± 13 years; 71% female) before and 6 months after starting GLP-1RA...
February 1, 2024: Diabetes Care
https://read.qxmd.com/read/38300889/neuropathic-pain-with-and-without-diabetic-peripheral-neuropathy-in-type-1-diabetes
#36
JOURNAL ARTICLE
Barbara H Braffett, Laure El Ghormli, James W Albers, Eva L Feldman, William H Herman, Rose A Gubitosi-Klug, Catherine L Martin, Trevor J Orchard, Neil H White, John M Lachin, Bruce A Perkins, Rodica Pop-Busui
OBJECTIVE: Diabetic peripheral neuropathy (DPN) is common; however, the features and burden of neuropathic pain (NP) in type 1 diabetes (T1D) are poorly understood. We evaluated the incidence of first occurrence, annual prevalence, remission, and risk factors for NP during long-term follow-up of participants with T1D. RESEARCH DESIGN AND METHODS: The Michigan Neuropathy Screening Instrument (MNSI) was administered annually (1994-2020) for 1,324 participants in the Epidemiology of Diabetes Interventions and Complications (EDIC) study...
February 1, 2024: Diabetes Care
https://read.qxmd.com/read/38295402/the-glucose-management-indicator-time-to-change-course
#37
JOURNAL ARTICLE
Elizabeth Selvin
Laboratory measurement of hemoglobin A1c (HbA1c) has, for decades, been the standard approach to monitoring glucose control in people with diabetes. Continuous glucose monitoring (CGM) is a revolutionary technology that can also aid in the monitoring of glucose control. However, there is uncertainty in how best to use CGM technology and its resulting data to improve control of glucose and prevent complications of diabetes. The glucose management indicator, or GMI, is an equation used to estimate HbA1c based on CGM mean glucose...
January 31, 2024: Diabetes Care
https://read.qxmd.com/read/38295397/severe-hypoglycemia-and-impaired-awareness-of-hypoglycemia-persist-in-people-with-type-1-diabetes-despite-use-of-diabetes-technology-results-from-a-cross-sectional-survey
#38
JOURNAL ARTICLE
Jennifer L Sherr, Lori M Laffel, Jingwen Liu, Wendy Wolf, Jeoffrey Bispham, Katherine S Chapman, Daniel Finan, Lina Titievsky, Tina Liu, Kaitlin Hagan, Jason Gaglia, Keval Chandarana, Richard Bergenstal, Jeremy Pettus
OBJECTIVE: To determine how diabetes technologies, including continuous glucose monitoring (CGM) and automated insulin delivery (AID) systems, impact glycemic metrics, prevalence of severe hypoglycemic events (SHEs), and impaired awareness of hypoglycemia (IAH) in people with type 1 diabetes in a real-world setting within the U.S. RESEARCH DESIGN AND METHODS: In this retrospective, observational study with cross-sectional elements, participants aged ≥18 years were enrolled from the T1D Exchange Registry/online community...
January 31, 2024: Diabetes Care
https://read.qxmd.com/read/38295394/empagliflozin-reduces-liver-fat-in-individuals-with-and-without-diabetes
#39
JOURNAL ARTICLE
Siham Abdelgani, Ahmed Khattab, John Adams, Gozde Baskoy, Marissa Brown, Geoff Clarke, Olga Larvenenko, Ralph A DeFronzo, Muhammad Abdul-Ghani
OBJECTIVE: To examine the effect of empagliflozin on liver fat content in individuals with and without type 2 diabetes (T2D) and the relationship between the decrease in liver fat and other metabolic actions of empagliflozin. RESEARCH DESIGN AND METHODS: Thirty individuals with T2D and 27 without were randomly assigned to receive in double-blind fashion empagliflozin or matching placebo (2:1 ratio) for 12 weeks. Participants underwent 75-g oral glucose tolerance testing and measurement of liver fat content with MRS before therapy and at study end...
January 31, 2024: Diabetes Care
https://read.qxmd.com/read/38290134/a-real-world-prospective-study-of-the-effectiveness-and-safety-of-automated-insulin-delivery-compared-with-other-modalities-of-type-1-diabetes-treatment-during-ramadan-intermittent-fasting
#40
JOURNAL ARTICLE
Mohammed E Al-Sofiani, Sahar Alharthi, Sarah Albunyan, Naweed Alzaman, David C Klonoff, Abdullah Alguwaihes
OBJECTIVE: To compare the fasting experience and glycemic control during Ramadan among people with type 1 diabetes (PWT1D) who use automated insulin delivery (AID) versus other modalities of treatment. RESEARCH DESIGN AND METHODS: A total of 294 PWT1D who attempted fasting during Ramadan in 2022 were categorized on the basis of treatment modality into one of five groups: 1) AID (n = 62); 2) conventional pump + continuous glucose monitoring (CGM; n = 37); 3) pump + self-monitoring of blood glucose (SMBG; n = 8); 4) multiple daily injections (MDI) + CGM (n = 155); and 5) MDI + SMBG (n = 32)...
January 30, 2024: Diabetes Care
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