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Developmental Medicine and Child Neurology

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https://www.readbyqxmd.com/read/30099738/sleep-deprivation-versus-melatonin-to-induce-sleep-during-paediatric-electroencephalography
#1
Zenobia Zaiwalla
No abstract text is available yet for this article.
August 11, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30084489/maternal-obesity-and-risk-of-cerebral-palsy-in-children-a-systematic-review-and-meta-analysis
#2
REVIEW
Jian Zhang, Linrui Peng, Qingxian Chang, Ruoting Xu, Nanbert Zhong, Qitao Huang, Mei Zhong, Yanhong Yu
AIM: Several studies have examined the links between maternal obesity and the risk of cerebral palsy (CP) in children, with inconsistent results. The aim of our study was to investigate whether maternal obesity is associated with increased risk of CP in offspring by using meta-analysis. METHOD: PubMed and Web of Science were searched until August 2017. Observational studies relevant to the maternal obesity and risk of CP in children were extracted and compiled. Meta-analyses were performed for different obesity levels and pooled odds ratios (ORs) and 95% confidence intervals (CIs) were reported...
August 7, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30084487/apolipoprotein-e-gene-polymorphisms-and-intraventricular-haemorrhage-in-infants-born-preterm-a-large-prospective-multicentre-cohort-study
#3
Mark Dzietko, Soeren Schulz, Michael Preuss, Christoph Haertel, Anja Stein, Ursula Felderhoff-Mueser, Wolfgang Goepel
AIM: Infants born preterm are at risk of intraventricular haemorrhage (IVH) but individual susceptibility related to genes is not well defined in this vulnerable population. Apolipoprotein genotypes APOE2 and APOE4 increase the hazard of cerebral haemorrhages in adults. We investigated whether APOE is associated with prevalence of IVH and is likely to have a particular genotype. METHOD: In this prospective study, 5075 infants born preterm with genotype APOE3 were compared to 965 (APOE2) and 1912 (APOE4) individuals, to analyse the association between APOE genotype and grade III and IV IVH...
August 7, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30084485/epigenetics-of-fragile-x-syndrome-and-fragile-x-related-disorders
#4
REVIEW
Claudine M Kraan, David E Godler, David J Amor
The fragile X mental retardation 1 gene (FMR1)-related disorder fragile X syndrome (FXS) is the most common heritable form of cognitive impairment and the second most common cause of comorbid autism. FXS usually results when a premutation trinucleotide CGG repeat in the 5' untranslated region of the FMR1 gene (CGG 55-200) expands over generations to a full mutation allele (CGG >200). This expansion is associated with silencing of the FMR1 promoter via an epigenetic mechanism that involves DNA methylation of the CGG repeat and the surrounding regulatory regions...
August 7, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30084484/recurrent-pregnancy-loss-and-neurological-deficits-in-offspring-confirmation-should-precede-modifications-in-patient-counselling
#5
Jennifer L Barkin
No abstract text is available yet for this article.
August 7, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30079517/parent-report-instruments-for-assessing-feeding-difficulties-in-children-with-neurological-impairments-a-systematic-review
#6
REVIEW
Nurul Hazirah Jaafar, Azizah Othman, Noorizan A Majid, Sakinah Harith, Zamh Zabidi-Hussin
AIM: This study aimed to review the psychometric properties and clinical application of parent-report instruments that assess feeding difficulties in children with neurological impairments. METHOD: Papers were identified through five electronic databases based on 15 keywords and were included if they met the following criteria: published in English, described the implementation of parent-report instruments, and included children with neurological impairments (either in the report or a related study population)...
August 5, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30073667/predictors-affecting-outcome-after-single-event-multilevel-surgery-in-children-with-cerebral-palsy-a-systematic-review
#7
REVIEW
Tomos A Edwards, Tim Theologis, James Wright
AIM: To review the potential predictors of outcome after single-event multilevel surgery (SEMLS) in children with cerebral palsy (CP). METHOD: A literature search using the following criteria was performed in six electronic databases: (1) children with cerebral palsy; (2) analysed potential predictors of outcome after SEMLS; (3) minimum 12 months follow-up. The potential predictors were predefined: sex; topographical distribution; socio-economic status; Gross Motor Function Classification System (GMFCS) level; preoperative kinematic summary statistic; age at surgery...
August 2, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30058166/maternal-recurrent-pregnancy-loss-is-associated-with-an-increased-risk-for-long-term-neurological-morbidity-in-offspring
#8
Dorit Paz Levy, Tamar Wainstock, Eyal Sheiner, Ruslan Sergienko, Daniella Landau, Asnat Walfisch
AIM: To determine whether maternal history of recurrent pregnancy loss (RPL) impacts on the long-term neurological health of the offspring. METHOD: A population-based cohort analysis was performed, including all singletons born between 1991 and 2014 at a single regional tertiary centre. Neurological morbidity up to age 18 years (including cognitive, motor, and psychiatric disorders) in children born to mothers with and without a history of RPL was compared. Cumulative neurological morbidity incidence was compared with survival curves and a Weibull multivariable survival model to control for follow-up time and relevant confounders...
July 29, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30058146/non-pharmacological-interventions-for-non-respiratory-sleep-disturbance-in-children-with-neurodisabilities-a-systematic-review
#9
REVIEW
Arabella Scantlebury, Catriona Mcdaid, Vicki Dawson, Heather Elphick, Caroline Fairhurst, Catherine Hewitt, Adwoa Parker, Gemma Spiers, Megan Thomas, Kath Wright, Bryony Beresford
AIM: To describe existing evidence on non-pharmacological interventions to manage sleep disturbance in children with neurodisabilities. METHOD: We systematically reviewed non-pharmacological interventions aimed at improving non-respiratory sleep disturbance in children with neurodisability. Sixteen databases, grey literature, and reference lists of included papers were searched up to February 2017. Two researchers (B.B., C.M., G.S., A.S., A.P.) undertook screening, data extraction, and quality appraisal...
July 29, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30058069/development-and-content-validation-of-the-muscular-dystrophy-child-health-index-of-life-with-disabilities-questionnaire-for-children-with-duchenne-muscular-dystrophy
#10
Roni Propp, Laura McAdam, Aileen M Davis, Nancy M Salbach, Shannon Weir, Clarissa Encisa, Unni G Narayanan
AIM: To develop a patient-reported outcome measure that comprehensively captures the health-related priorities of children with Duchenne muscular dystrophy (DMD). METHOD: Children with DMD and their parents completed the iteratively revised versions of the Caregiver Priorities and Child Health Index of Life with Disabilities (CPCHILD), followed by a cognitive interview to develop a pilot version of a new measure. Multidisciplinary health care professionals completed an item-by-item analysis of the measure and a 14-item sensibility questionnaire...
July 29, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30051911/the-underlying-mechanisms-of-neurobehavioral-risks-in-sex-chromosome-trisomies
#11
Sophie van Rijn
No abstract text is available yet for this article.
July 27, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30051908/self-report-of-pain-in-young-people-and-adults-with-spastic-cerebral-palsy-interrater-reliability-of-the-revised-face-legs-activity-cry-and-consolability-r-flacc-scale-ratings
#12
Margaret A Fox, Rita Ayyangar, Rebecca Parten, Heidi J Haapala, Stephen G Schilling, Claire Z Kalpakjian
AIM: People with cerebral palsy (CP) are often unable to express pain owing to cognitive or speech impairments. Reports that rely on observation can be inaccurate, because behaviours such as grimacing, common in people with spastic CP, resemble pain expressions. We examined preliminary validity and reliability of the revised Face, Legs, Activity, Cry, and Consolability (r-FLACC) scale in people with spastic CP. METHOD: Forty-eight young people and adults (35 females, 13 males; mean [SD] age 29y 2mo [13y]) were video-recorded during a standard examination, rating their pain (0-10) afterwards...
July 27, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30028505/structural-brain-abnormalities-in-adolescents-and-young-adults-with-congenital-heart-defect-a-systematic-review
#13
REVIEW
Marie-Eve Bolduc, Heather Lambert, Sylviya Ganeshamoorthy, Marie Brossard-Racine
AIM: The primary objective of this systematic review is to define and quantify brain structural abnormalities present in adolescents and young adults with complex congenital heart defect (CHD). We also aim to evaluate the extent to which these structural abnormalities are associated with functional outcomes. METHOD: A search of studies examining brain structure by magnetic resonance imaging in adolescents and young adults with complex CHD was performed in Embase, MEDLINE, and Web of Science...
July 20, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30028504/sleep-deprivation-and-melatonin-for-inducing-sleep-in-paediatric-electroencephalography-a-prospective-multicentre-service-evaluation
#14
James Jp Alix, Rosalind H Kandler, Catherine Pang, Theocharis Stavroulakis, Santiago Catania
AIM: To compare the efficacy of the main methodologies in attaining sleep and electroencephalography (EEG) abnormalities in children with a view to producing recommendations on best practice. METHOD: Fifty-one UK centres participated. Methods for sleep induction (sleep deprivation, melatonin, and combined sleep deprivation/melatonin) were compared. Data pertaining to demographics, achievement of stage II sleep, and recording characteristics (duration of study, presence of epileptiform activity in awake/sleep states) were prospectively collected for consecutive patients in November and December 2013...
July 20, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30028502/austerity-and-families-with-disabled-children-a-european-survey
#15
Karen A Horridge, Rosie Dew, Alain Chatelin, Arnab Seal, Lourdes Merio Macias, Giovanni Cioni, Oleh Kachmar, Scott Wilkes
AIM: To describe the impact austerity measures have had on families with disabled children across Europe and on professionals providing services for them. METHOD: Cross-sectional surveys were disseminated via professional and family networks in 32 European countries for 3 months from December 2016. RESULTS: Families (n=731), of whom 45% met UNICEF criteria for severe poverty, and professionals (n=959) responded from 23 and 32 countries respectively...
July 20, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30028500/the-need-for-specific-paediatric-tools-for-stroke-recognition
#16
Bernard Dachy
No abstract text is available yet for this article.
July 20, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30022476/measures-used-to-quantify-participation-in-childhood-disability-and-their-alignment-with-the-family-of-participation-related-constructs-a-systematic-review
#17
REVIEW
Brooke Adair, Anna Ullenhag, Peter Rosenbaum, Mats Granlund, Deb Keen, Christine Imms
AIM: We aimed to identify measures used to assess the participation of disabled children and to map the measures' content to the family of participation-related constructs (fPRC) to inform future research and practice. METHOD: Six databases were searched to identify measures used to assess participation in health, psychology, and education research. Included studies involved children aged 0 to 18 years with a permanent impairment or developmental disability and reported use of a quantitative measure of participation...
July 19, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29998559/the-gap-between-current-knowledge-and-clinical-practice-in-childhood-disability
#18
Elisabet Rodby-Bousquet
No abstract text is available yet for this article.
July 11, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29998486/use-of-the-activlim-cp-questionnaire-gauging-daily-performance-in-children-with-cerebral-palsy
#19
Christopher J Newman
No abstract text is available yet for this article.
July 11, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29992541/assessing-the-accuracy-of-the-modified-checklist-for-autism-in-toddlers-a-systematic-review-and-meta-analysis
#20
REVIEW
Tracy Yuen, Melanie Penner, Melissa T Carter, Peter Szatmari, Wendy J Ungar
AIM: The Modified Checklist for Autism in Toddlers (M-CHAT) could be appropriate for universal screening for autism spectrum disorder (ASD) at 18 months and 24 months. Validation studies, however, reported differences in psychometric properties across sample populations. This meta-analysis summarized its accuracy measures and quantified their change in relation to patient and study characteristics. METHOD: Four electronic databases (MEDLINE, PsycINFO, CINAHL, and Embase) were searched to identify articles published between January 2001 and May 2016...
July 11, 2018: Developmental Medicine and Child Neurology
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