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Current Opinion in Allergy and Clinical Immunology

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https://www.readbyqxmd.com/read/28141629/a-wide-scope-of-new-developments-in-occupational-allergy-and-clinical-immunology
#1
Susan M Tarlo, Piero Maestrelli
No abstract text is available yet for this article.
January 30, 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28141628/traffic-related-air-pollution-and-allergic-disease-an-update-in-the-context-of-global-urbanization
#2
Christopher Carlsten, Christopher F Rider
PURPOSE OF REVIEW: The review aims to give an update on the literature around traffic-related air pollution (TRAP) and allergic disease in the context of global urbanization, as the most populous countries in the world face severe TRAP exposure challenges. RECENT FINDINGS: As research continues to show that gene-environment interactions and epigenetics contribute to the TRAP-allergy link, evidence around the links to climate change grows. Greenspace may provide a buffer to adverse effects of traffic on health, overall, but pose risks in terms of allergic disease...
January 30, 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28141627/editorial-moving-ahead-faster-than-ever
#3
Leonard B Bacharier, Stanley J Szefler
No abstract text is available yet for this article.
January 30, 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28141625/social-media-use-for-occupational-lung-disease
#4
Philip Harber, Gondy Leroy
PURPOSE OF REVIEW: Social media have great impact on all aspects of life throughout the world. The utilization of social media for occupational lung disease, however, has been much more limited. This article summarizes recent literature concerning social media for occupational lung disease and identifies areas for additional use. RECENT FINDINGS: Social media are used in six relevant areas: information dissemination, peer-to-peer communication, survey research data collection, participatory research and exposome data acquisition, assessing public concerns, and knowledge generation...
January 30, 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28403019/food-labeling-issues-in-patients-with-severe-food-allergies-solving-a-hamlet-like-doubt
#5
Vincenzo Fierro, Francesco Di Girolamo, Valeria Marzano, Lamia Dahdah, Maurizio Mennini
PURPOSE OF REVIEW: We review the laws on labeling in the international community, the difficulties they pose to the food manufacturers to prepare the food labels and the methodologies to determine the concentration of potential allergens in foods. RECENT FINDINGS: European Food Safety Authority and International Life Sciences Institute Europe are evaluating strategies to identify the threshold level of allergen that can trigger a reaction in individuals. The most used techniques to detect the presence of protein in food are Enzyme-linked immunosorbent assay, polymerase chain reaction and real time polymerase chain reaction...
June 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28379866/editorial-outcome-measures
#6
R Maximiliano Gómez, Henry Milgrom
No abstract text is available yet for this article.
June 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28379865/severe-food-allergies-can-they-be-considered-rare-diseases
#7
Alessandro Fiocchi, Motohiro Ebisawa
No abstract text is available yet for this article.
June 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28375933/use-of-biologics-in-severe-food-allergies
#8
Alessandro Fiocchi, Valentina Pecora, Rocco L Valluzzi, Vincenzo Fierro, Maurizio Mennini
PURPOSE OF REVIEW: Severe cases of food allergy account for the majority of the burden in terms of risks, quality of life, and resource expenditure. The traditional approach to these forms has been strict avoidance. More recently, Oral ImmunoTherapy (OIT) has gained a role in their management. However, in severe food allergies OIT is often infeasible. RECENT FINDINGS: Case reports, observational, and prospective studies have recently proposed different approaches to severe food allergy...
June 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28375932/outstanding-animal-studies-in-allergy-ii-from-atopic-barrier-and-microbiome-to-allergen-specific-immunotherapy
#9
Erika Jensen-Jarolim, Isabella Pali-Schöll, Franziska Roth-Walter
PURPOSE OF REVIEW: Animal studies published within the past 18 months were assessed, focusing on innate and specific immunomodulation, providing knowledge of high translational relevance for human atopic and allergic diseases. RECENT FINDINGS: Allergic companion animals represent alternative models, but most studies were done in mice. Atopic dermatitis mouse models were refined by the utilization of cytokines like IL-23 and relevant skin allergens or enzymes. A novel IL-6 reporter mouse allows biomonitoring of inflammation...
June 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28362676/behavioral-interventions-to-improve-asthma-outcomes-a-systematic-review-of-recent-publications
#10
Giselle S Mosnaim, Esra Akkoyun, Joshua Eng, Madeleine U Shalowitz
PURPOSE OF REVIEW: Asthma outcomes are influenced by factors at multiple ecological levels: the individual and his/her family, home, medical care, and community. This systematic review describes recently published single-level and multilevel behavioral interventions to improve asthma outcomes. RECENT FINDINGS: Of the 23 total title/abstracts reviewed in the original systematic search of PubMed, Ovid, Scopus, PsychINFO, and CIHAHL reference review databases, six met inclusion criteria...
June 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28362675/novel-immunotherapy-and-treatment-modality-for-severe-food-allergies
#11
Ken-Ichi Nagakura, Sakura Sato, Noriyuki Yanagida, Motohiro Ebisawa
PURPOSE OF REVIEW: In recent years, many studies on oral immunotherapy (OIT) have been conducted; however, few have focused on severe food allergies. The purpose of this review was to assess the efficacy and safety of oral immunotherapies for patients with severe food allergy. RECENT FINDINGS: We reviewed multiple immunotherapy reports published within a few years or reports focusing on severe food allergies. We also investigated recent studies on OIT and novel food allergy management...
June 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28350555/apheresis-in-food-allergies
#12
Lamia Dahdah, Giovanna Leone, Mariacristina Artesani, Carla Riccardi, Oscar Mazzina
PURPOSE OF REVIEW: The prevalence of IgE-mediated food allergy and anaphylaxis has risen rapidly in developed countries, and countries with rapid industrialization may follow. Therapies include elimination diets, Oral ImmunoTherapy, and the administration of biologics, but high serum IgE levels may preclude their use. Consequently, decreasing IgE becomes a rational approach and could be obtained by immunoapheresis. The aim of this review is to evaluate the rationale and advantages of immunoapheresis...
June 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28346234/outstanding-animal-studies-in-allergy-i-from-asthma-to-food-allergy-and-anaphylaxis
#13
Erika Jensen-Jarolim, Isabella Pali-Schöll, Franziska Roth-Walter
PURPOSE OF REVIEW: Animal models published within the past 18 months on asthma, food allergy and anaphylaxis, all conditions of rising public health concern, were reviewed. RECENT FINDINGS: While domestic animals spontaneously develop asthma, food allergy and anaphylaxis, in animal models, divergent sensitization and challenge routes, dosages, intervals and antigens are used to induce asthmatic, food allergic or anaphylactic phenotypes. This must be considered in the interpretation of results...
June 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28333691/asthma-prevalence-and-severity-in-low-resource-communities
#14
Álvaro A Cruz, Rafael Stelmach, Eduardo V Ponte
PURPOSE OF REVIEW: The prevalence of asthma was thought to be low in most low-income countries, but several reports have indicated this is not always true. This is a narrative review of recent publications on the burden of asthma in low and middle-income countries (LMIC) and underprivileged communities from developed countries. RECENT FINDINGS: Several studies have reported a low prevalence of asthma is LMIC, but indicate it is increasing. In the last few years, however, many surveys demonstrated this may not always be true...
June 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28323676/impact-of-elimination-diets-on-nutrition-and-growth-in-children-with-multiple-food-allergies
#15
Carina Venter, Alessandra Mazzocchi, Kate Maslin, Carlo Agostoni
PURPOSE OF REVIEW: Growth and nutritional intake of children with cows' milk allergy and other food allergens has been thoroughly investigated in recent years across many different countries and age groups. An impaired growth in atopic children should not be attributed only to a high number of allergens and foods to be avoided, but to a general condition of 'sub-inflammation', which unfavorably affects the absorption and utilization of fuel and substrates. Atopic study participants may represent a good target for personalized nutrition and in this review we sought to outline many of the issues that should be taken into account when dietitians advise patients regarding food avoidance and expected effects on growth...
June 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28225363/pediatric-asthma-moving-ahead-faster-than-ever
#16
Leonard B Bacharier, Stanley J Szefler
No abstract text is available yet for this article.
April 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28177950/building-school-health-partnerships-to-improve-pediatric-asthma-care-the-school-based-asthma-management-program
#17
Sujani Kakumanu, Nicholas Antos, Stanley J Szefler, Robert F Lemanske
PURPOSE OF REVIEW: Children with asthma require care that is seamlessly coordinated so that asthma symptoms are recognized and managed at home and at school. The purpose of this review is to discuss recent consensus recommendations in school-based asthma care. RECENT FINDINGS: The School-based Asthma Management Program (SAMPRO) provides a widely endorsed framework to coordinate care with schools and consists of four components: establishing a circle of support around the child with asthma; facilitating bidirectional communication between clinicians and schools; comprehensive asthma education for schools; and assessment and remediation of environmental asthma triggers at school...
April 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28177949/progress-with-structure-activity-relationship-modelling-of-occupational-chemical-respiratory-sensitizers
#18
Martin J Seed, Raymond M Agius
PURPOSE OF REVIEW: This appraises currently available computer-based ('in silico') models relating the molecular structure of low molecular weight compounds to their respiratory sensitization hazard. The present review places focus on the two main applications of such structure--activity relationship (SAR) models: hypotheses on disease mechanisms and toxicological prediction. RECENT FINDINGS: Analyses of the chemical structures of low molecular weight organic compounds known to have caused occupational asthma has led to the development of mechanistic alerts usually based on electrophilic reaction chemistry and protein cross-linking potential...
April 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28177948/silicosis-and-autoimmunity
#19
Suni Lee, Hiroaki Hayashi, Hidenori Mastuzaki, Naoko Kumagai-Takei, Takemi Otsuki
PURPOSE OF REVIEW: Of the various environmental, occupational, and medical substances that cause dysregulation of autoimmunity, the effects and causative mechanisms of silica particles and asbestos fibers are discussed in this review. RECENT FINDINGS: With respect to silica, many epidemiological studies have shown a significant association between silica exposure and the occurrence of autoimmune diseases. Although the importance of the NACHT, LRR and PYD domains-containing protein 3 (NALP3) inflammasome as the initial immune reaction against silica particles has been identified, the mechanisms involved that lead to various autoimmune diseases in patients exposed to silica remain largely unknown...
April 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28141626/update-on-asthma-and-cleaning-agents
#20
Ilenia Folletti, Andrea Siracusa, Giulia Paolocci
PURPOSE OF REVIEW: Asthma due to cleaning products has been known for 20 years, and the interest in this topic is still large because of the number of cleaning workers with respiratory problems. In this review, we sought to highlight the most recent findings on the relationship between exposure to cleaning products and asthma and to summarize the specific literature published between 2013 and 2016. RECENT FINDINGS: Women are confirmed as most of workers exposed to cleaning products and have a higher frequency than men of work-related respiratory symptoms and diseases...
April 2017: Current Opinion in Allergy and Clinical Immunology
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