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Contact Dermatitis

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https://www.readbyqxmd.com/read/28555927/sensitization-and-cross-reactivity-patterns-of-contact-allergy-to-diisocyanates-and-corresponding-amines-investigation-of-diphenylmethane-4-4-diisocyanate-diphenylmethane-4-4-diamine-dicyclohexylmethane-4-4-diisocyanate-and-dicylohexylmethane-4-4-diamine
#1
Haneen Hamada, Magnus Bruze, Erik Zimerson, Marléne Isaksson, Malin Engfeldt
BACKGROUND: Isocyanates are used in polyurethane production. Dermal exposure to isocyanates can induce contact allergy. The most common isocyanate is diphenylmethane diisocyanate used for industrial purposes. The isomer diphenylmethane-4,4'-diisocyanate (4,4'-MDI) is used in patch testing. Diphenylmethane-4,4'-diamine (4,4'-MDA) is its corresponding amine. Concurrent reactions to 4,4'-MDI and 4,4'-MDA have been reported, as have concurrent reactions to 4,4'-MDI and dicyclohexylmethane-4,4'-diisocyanate (4,4'-DMDI)...
May 29, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28555887/in-vitro-detection-of-chemical-allergens-an-optimized-assay-using-mouse-bone-marrow-derived-dendritic-cells
#2
Fabrice Battais, Cécile Huppert, Isabelle Langonné, Samuel Muller, Isabelle Sponne
BACKGROUND: Identification of the allergenic potency of chemicals is a key step in the safety assessment process. Predictive assays that require no or few animals are needed. OBJECTIVES: To develop an alternative in vitro mouse bone marrow-derived dendritic cell (BMDC) assay to determine the allergenic potential of chemicals. METHODS: BMDCs were exposed to well-known allergens and to non-allergenic chemicals. Surface marker expression and cytokine release of BMDCs were analysed after treatment...
May 29, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28543097/contact-dermatitis-as-an-adverse-reaction-to-some-topically-used-european-herbal-medicinal-products-part-4-solidago-virgaurea-vitis-vinifera
#3
REVIEW
Paola L Minciullo, Gioacchino Calapai, Marco Miroddi, Carmen Mannucci, Ioanna Chinou, Sebastiano Gangemi, Richard J Schmidt
This review focuses on contact dermatitis as an adverse effect of a selection of topically used herbal medicinal products for which the European Medicines Agency has completed an evaluation up to the end of November 2013 and for which a Community herbal monograph - now (since 2014) called a 'European Union herbal monograph' - has been produced. The present part 4 addresses species from Solidago virgaurea L. to Vitis vinifera L.
May 23, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28524256/quantification-of-l-carvone-in-toothpastes-available-on-the-swedish-market
#4
Liv Kroona, Gunnar Warfvinge, Marléne Isaksson, Camilla Ahlgren, Jakob Dahlin, Östen Sörensen, Magnus Bruze
BACKGROUND: Toothpastes have widespread use in the population, and contain flavours used to give a pleasant and often minty aroma. Flavours are prevalent allergens in toothpastes, and adverse reactions often present as perioral dermatitis or stomatitis. l-Carvone, a mint flavour found in spearmint oil, is one of these allergens. There are few studies on contact allergy to l-carvone, and some of them have indicated a positive relationship with oral lichenoid lesions. OBJECTIVES: To qualitatively and quantitatively investigate the presence of l-carvone in commercially available toothpastes on the Swedish market...
May 19, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28511284/non-mix-fragrances-are-top-sensitizers-in-consecutive-dermatitis-patients%C3%A2-%C3%A2-a-cross-sectional-study-of-the-26-eu-labelled-fragrance-allergens
#5
Niels H Bennike, Claus Zachariae, Jeanne D Johansen
BACKGROUND: For cosmetics, it is mandatory to label 26 fragrance substances, including all constituents of fragrance mix I (FM I) and fragrance mix II (FM II). Earlier reports have not included oxidized R-limonene [hydroperoxides of R-limonene (Lim-OOH)] and oxidized linalool [hydroperoxides of linalool (Lin-OOH)], and breakdown testing of FM I and FM II has mainly been performed in selected, mix-positive patients. OBJECTIVES: To report the prevalence of sensitization to the 26 fragrances, and to assess concomitant reactivity to FM I and/or FM II...
May 16, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28504363/allergic-contact-dermatitis-caused-by-meth-acrylates-in-nail-cosmetic-products-in-users-and-nail-technicians%C3%A2-%C3%A2-a-5-year-study
#6
Inês Raposo, Inês Lobo, Cristina Amaro, Maria de Lurdes Lobo, Helena Melo, Joana Parente, Teresa Pereira, Joana Rocha, Ana P Cunha, Armando Baptista, Pedro Serrano, Teresa Correia, Ana R Travassos, Margarida Dias, Fátima Pereira, Margarida Gonçalo
BACKGROUND: The increasing use of long-lasting nail aesthetic products has led to a growing number of cases of allergic contact dermatitis (ACD) caused by (meth)acrylates in recent years. OBJECTIVES: To provide information on ACD caused by (meth)acrylates related to nail cosmetic products. METHODS: We retrospectively reviewed files of patients with ACD caused by (meth)acrylates related to nail cosmetic products, who were patch tested between January 2011 and December 2015 in 13 departments of dermatology in Portugal...
May 15, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28497472/current-knowledge-on-biomarkers-for-contact-sensitization-and-allergic-contact-dermatitis
#7
REVIEW
Sjors A Koppes, Kristiane A Engebretsen, Tove Agner, Irena Angelova-Fischer, Teresa Berents, Johanna Brandner, Richard Brans, Maja-Lisa Clausen, Edith Hummler, Ivone Jakasa, Ružica Jurakić-Tončic, Swen M John, Denis Khnykin, Sonja Molin, Jan O Holm, Sari Suomela, Hermann-Josef Thierse, Sanja Kezic, Stefan F Martin, Jacob P Thyssen
Contact sensitization is common and affects up to 20% of the general population. The clinical manifestation of contact sensitization is allergic contact dermatitis. This is a clinical expression that is sometimes difficult to distinguish from other types of dermatitis, for example irritant and atopic dermatitis. Several studies have examined the pathogenesis and severity of allergic contact dermatitis by measuring the absence or presence of various biomarkers. In this review, we provide a non-systematic overview of biomarkers that have been studied in allergic contact dermatitis...
May 12, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28481015/guideline-for-translation-and-national-validation-of-the-quality-of-life-in-hand-eczema-questionnaire-qolheq
#8
Jart A F Oosterhaven, Marie L A Schuttelaar, Christian Apfelbacher, Thomas L Diepgen, Robert F Ofenloch
There is a need for well-developed and validated questionnaires to measure patient reported outcomes. The Quality of Life in Hand Eczema Questionnaire (QOLHEQ) is such a validated instrument measuring disease-specific health-related quality of life in hand eczema patients. A re-validation of measurement properties is required before an instrument is used in a new population. With the objective of arriving at a guideline for translation and national validation of the QOLHEQ, we have developed the design of a reference study on how to adequately assess measurement properties of the QOLHEQ based on interdisciplinary discussions and current standards...
May 8, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28449354/prevalence-of-and-work-related-risk-factors-for-hand-eczema-in-a-norwegian-general-population-the-hunt-study
#9
Hilde K Vindenes, Cecilie Svanes, Stein H L Lygre, Bjørg-Eli Hollund, Arnulf Langhammer, Randi J Bertelsen
BACKGROUND: Chemical exposures at work and at home may cause hand eczema. However, this has been scarcely described for Norway. OBJECTIVES: To investigate the prevalence of, and occupational risk factors for, hand eczema in Norway. METHODS: Among 50 805 respondents (aged ≥20 years) to the third Nord-Trøndelag Health Study (HUNT3), 5757 persons reported ever having hand eczema, and 4206 answered a hand eczema questionnaire. RESULTS: The lifetime prevalences of hand eczema were 8...
April 27, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28449346/airborne-allergic-contact-dermatitis-caused-by-isothiazolinones-in-water-based-paints-a-retrospective-study-of-44-cases
#10
Emmanuelle Amsler, Olivier Aerts, Nadia Raison-Peyron, Michèle Debons, Brigitte Milpied, Françoise Giordano-Labadie, Julie Waton, Marie C Ferrier-Le Bouëdec, Isabelle Lartigau, Catherine Pecquet, Haudrey Assier, Martine Avenel-Audran, Claire Bernier, Florence Castelain, Evelyne Collet, Marie-Noëlle Crépy, Nathalie Genillier, Pascal Girardin, Pauline Pralong, Florence Tetart, Dominique Vital-Durand, Angele Soria, Annick Barbaud
BACKGROUND: Airborne allergic contact dermatitis caused by paints containing isothiazolinones has been recognized as a health hazard. OBJECTIVES: To collect epidemiological, clinical and patch test data on airborne allergic contact dermatitis caused by isothiazolinone-containing paints in France and Belgium. METHODS: A descriptive, retrospective study was initiated by the Dermatology and Allergy Group of the French Society of Dermatology, including methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI)- and/or MI-sensitized patients who developed airborne allergic contact dermatitis following exposure to isothiazolinone-containing paint...
April 27, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28449188/development-validation-and-testing-of-a-skin-sampling-method-for-assessment-of-metal-exposure
#11
Behnaz Erfani, Klara Midander, Carola Lidén, Anneli Julander
BACKGROUND: Nickel, cobalt and chromium are frequent skin sensitizers. Skin exposure results in eczema in sensitized individuals, the risk being related to the skin dose. OBJECTIVES: To develop a self-sampling method for quantification of skin exposure to metals, to validate the method, and to assess its feasibility. METHODS: Defined metal doses (0.01-5 µg) were applied to the fingers of 5 participants. Skin areas (2 cm(2) ) were sampled with 1% HNO3 , either as 0...
April 27, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28444762/screening-allergic-reactions-to-resol-resin-based-on-phenol-and-formaldehyde-in-a-clinic-of-occupational-dermatology
#12
Kristiina Aalto-Korte, Katri Suuronen
BACKGROUND: Allergic reactions to resol-type phenol formaldehyde resin [phenol formaldehyde resin 2 (PFR2)] are relatively common. It has been suggested that PFR2 should be included in baseline series. However, a recent international study found clinical relevance in only 25% of patients. OBJECTIVES: To report the results of screening with PFR2 over a 5-year period (2012-2016), and to study the clinical relevance of allergic reactions to PFR2 over a 15-year period (2002-2016)...
April 25, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28425595/hand-eczema-atopic-dermatitis-and-filaggrin-mutations-in-adult-danes-a-registry-based-study-assessing-risk-of-disability-pension
#13
Nina G Heede, Betina H Thuesen, Jacob P Thyssen, Allan Linneberg, Pal B Szecsi, Steen Stender, Torkil Menné, Jeanne D Johansen
BACKGROUND: Atopic dermatitis and hand eczema often impair the ability of people to work. Only a few studies have investigated whether individuals with loss-of-function filaggrin gene (FLG) mutations, who often have severe and early onset of dermatitis, experience occupational consequences. OBJECTIVE: To investigate the personal consequences of having atopic dermatitis and/or hand eczema and FLG mutations. METHOD: Adult Danes from the general population (n = 3247) and patients with atopic dermatitis and/or hand eczema (n = 496) were genotyped for common FLG mutations, and completed a questionnaire about skin symptoms and hand eczema...
April 20, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28425114/a-multi-institutional-joint-study-of-contact-dermatitis-related-to-hair-colouring-and-perming-agents-in-japan
#14
Akiko Ito, Kazue Nishioka, Hiromi Kanto, Akiko Yagami, Shigeki Yamada, Mariko Sugiura, Chihiro Yasunaga, Keiko Yoshii, Hiromi Kobayashi, Atsuko Adachi, Yuko Ikezawa, Kumiko Washizaki, Shigeki Inui, Hitoshi Miyazawa, Naoki Oiso, Tokio Nakata, Kayoko Matsunaga
BACKGROUND: In Japan, allergic contact dermatitis caused by hair colouring agents is a considerable problem for those occupationally exposed and also for consumers. Over the last 20 years, p-phenylenediamine (PPD) has been a common allergen, with ∼7% positive patch test reactions. OBJECTIVES: To investigate which ingredients caused allergic contact dermatitis related to hair dye and perming solutions in Japan, to assess whether PPD is suitable for screening for hair dye allergy, and to propose allergens for a Japanese hairdresser series...
April 20, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28421670/an-epidemic-of-allergic-contact-dermatitis-caused-by-a-new-allergen-caprylhydroxamic-acid-in-moisturizers
#15
Leena Ackermann, Hannele Virtanen, Laura Korhonen, Arja Laukkanen, Laura Huilaja, Riitta Riekki, Taina Hasan
BACKGROUND: In 2016, dermatologists in Finland suspected contact allergy in several patients using moisturizers under the trade name Apobase®. Following a formulation change, Phenostat™, which is a mixture of phenoxyethanol, caprylhydroxamic acid, and methylpropanediol, was used as a preservative in Apobase® moisturizers in Finland. OBJECTIVES: To confirm the suspected contact allergy to Apobase® cream, oily cream, and/or lotion, and to identify the specific contact allergen and define its optimal patch test concentration...
April 19, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28386993/nickel-allergy-in-a-danish-population-25%C3%A2-years-after-the-first-nickel-regulation
#16
Malin G Ahlström, Torkil Menné, Jacob P Thyssen, Jeanne D Johansen
BACKGROUND: Nickel in metallic items has been regulated in Denmark since 1990; however, 10% of young Danish women are still sensitized to nickel. There is a need for continuous surveillance of the effect of regulation. OBJECTIVES: To identify current self-reported metallic exposures leading to dermatitis in nickel-allergic patients, and the minimum contact time needed for dermatitis to occur. METHODS: A questionnaire was sent to all patients who reacted positively to nickel sulfate 5% pet...
April 7, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28612445/severe-eyelid-allergic-contact-dermatitis-secondary-to-eyelash-tint-two-case-reports
#17
Lareb Ali, Jonathan S Foulds, Sharizan Abdul Ghaffar
No abstract text is available yet for this article.
July 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28612444/first-case-of-contact-dermatitis-caused-by-hydroxypropyl-tetrahydropyrantriol-used-in-an-anti-ageing-cream
#18
Haudrey Assier, Pierre Wolkenstein, Olivier Chosidow
No abstract text is available yet for this article.
July 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28612443/contact-urticaria-syndrome-caused-by-sulfamethoxazole-sodium-contained-in-eye-drops
#19
Yuriko Fujiwara, Naoko Inomata, Shuichi Ishida, Mami Miyakawa, Yuki Nomura, Naoko Mitani, Michiko Aihara
No abstract text is available yet for this article.
July 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28612442/allergic-contact-dermatitis-caused-by-arbutin-and-dipotassium-glycyrrhizate-in-skin-lightening-products
#20
Naoki Oiso, Megumi Tatebayashi, Yasuko Hoshiyama, Akira Kawada
No abstract text is available yet for this article.
July 2017: Contact Dermatitis
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