Michael Wennervaldt, Helen Vaher, Malin G Ahlström, Nuno Bischofberger, Torkil Menné, Jacob P Thyssen, Jeanne D Johansen, Charlotte M Bonefeld
BACKGROUND: Nickel is the leading cause of contact allergy in Europe, with 14.5% of the adult population being sensitized. Despite regulations limiting nickel release from consumer items, the incidence and prevalence of nickel allergy remain high. OBJECTIVE: To investigate the clinical and subclinical immune response to low-dose nickel exposure on nickel pre-exposed skin to assess the adequacy of current regulatory limits. METHOD: Nickel-allergic and healthy controls were patch tested with nickel twice with a 3-4 weeks interval...
April 5, 2024: Contact Dermatitis