journal
MENU ▼
Read by QxMD icon Read
search

Clinical Transplantation

journal
https://www.readbyqxmd.com/read/27888549/microscope-assisted-hepatic-artery-reconstruction-in-adult-living-donor-liver-transplantation-a-review-of-325-consecutive-cases-in-a-single-center
#1
Chen-Fang Lee, Johnny Chuieng Yi Lu, Ahmed Zidan, Ching-Song Lee, Tsung-Han Wu, Kun-Ming Chan, Wei-Chen Lee
BACKGROUND: Despite the technical and medical improvements in the recent years, hepatic artery thrombosis (HAT) remains a devastating complication after living donor liver transplantation (LDLT). We described our surgical techniques and monitoring protocols for hepatic artery reconstruction. We reported one of the lowest incidence rates of HAT in the literature. METHODS: Between 2008 and 2015, a total of 325 LDLTs performed at our institute were retrospectively analyzed...
November 26, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27888540/higher-dose-of-cd34-peripheral-blood-stem-cells-is-associated-with-better-survival-after-haploidentical-stem-cell-transplantation-in-pediatric-patients
#2
Yao Chen, Lan-Ping Xu, Kai-Yan Liu, Huan Chen, Yu-Hong Chen, Xiao-Hui Zhang, Yu Wang, Feng-Rong Wang, Wei Han, Jing-Zhi Wang, Chen-Hua Yan, Xiao-Jun Huang
Haploidentical stem cell transplantation (SCT) is increasingly used to treat pediatric patients with malignant or non-malignant hematological disorders. The CD34+ dose of bone marrow or peripheral blood stem cells (PBSCs) has been shown to be an important determinant of the transplant outcome in adults under various preparative regimens. However, knowledge of the effect of the CD34+ dose in pediatric haploidentical SCT is limited. We analyzed the data of 348 pediatric patients (aged 2-18 years) with acute or chronic leukemia, myelodysplastic syndrome (MDS), and other hematological disorders that received a transplant between 2002 and 2012...
November 26, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27888534/early-steroid-withdrawal-results-in-improved-patient-and-graft-survival-and-lower-risk-of-post-transplant-cardiovascular-risk-profiles-a-single-center-10-year-experience
#3
Reynold Lopez-Soler, Ryan Chan, Jessica Martinolich, Lisa Park, Ashar Ata, Nikolaos Chandolias, David Conti
Long term use of steroids results in predictable secondary effects that can lead to increased morbidity and mortality. In this study, we present 10 years' worth of data of early steroid withdrawal (ESW) immunosuppression consisting of Mycophenolate, Sirolimus, and Tacrolimus. From 2003 to 2013, 563 kidney transplant recipients were weaned off steroids prior to discharge. We compared outcomes with that of our 65 historical controls maintained on steroids. We analyzed graft and patient survival and determined the incidence of steroid-related comorbidities such as hypertension, hypercholesterolemia, diabetes, coronary artery disease, and weight gain...
November 26, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27888532/biliary-strictures-complicating-liver-transplantation-in-pediatric-patients-experience-in-a-south-american-transplant-center
#4
A Holguin, S Rodriguez-Takeuchi, L Ospina, D Acosta, V Botero, L Thomas, J Villegas, G Echeverri, L Caicedo
OBJECTIVE: To describe the experience of percutaneous transhepatic cholangiography (PTC) with biliary dilatation and drainage after pediatric liver transplantation, and to determine the long-term outcome of this procedure. METHODS: Retrospective study from 2001 to 2013. Follow-up after treatment was also undertaken. A survival analysis was performed in patients in whom the procedure and eventual removal of the catheter were successful. RESULTS: In all, 196 children received liver transplants; 40 of them (20 boys and 20 girls; median age of 4 years) were treated using PTC due to biliary complications...
November 26, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27888522/barriers-to-the-use-of-a-federal-travel-grant-by-living-kidney-donors
#5
Rebecca Hays, Amy Elaine Thomas, Erin Mathias, Joshua Mezrich, Didier A Mandelbrot
Living organ donation involves significant out of pocket costs, which burden donor candidates and may be an obstacle to donation. There is a single US grant (the National Living Donor Assistance Center- NLDAC) to cover live donor travel costs. Though there may be center-specific variability in grant utilization, prospective donors - and their intended recipients- must also meet eligibility criteria. In fact, the NLDAC grant is used by <10% of US live donors annually. We studied 154 consecutive kidney donor clinic evaluations (11/01/14-08/30/15) to determine eligibility and usage patterns during the evaluation process...
November 26, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27862341/cost-and-clinical-outcome-of-islet-transplantation-in-norway-2010-2015
#6
Simen W Schive, Aksel Foss, Afaf Sahraoui, Kristine Kloster-Jensen, Geir Hafsahl, Gunnar Kvalheim, Torbjørn Lundgren, Bengt von Zur-Mühlen, Marie Felldin, Ehab Rafael, Marko Lempinen, Olle Korsgren, Trond G Jenssen, Vinod Mishra, Hanne Scholz
Islet transplantation is a minimally invasive β-cell replacement strategy. Islet transplantation is a reimbursed treatment in Norway. Here we summarize the cost and clinical outcome of 31 islet transplantations performed at Oslo University Hospital (OUS) from Januray 2010 - June 2015. Patients were retrospectively divided into 3 groups. 13 patients received either one or two islet transplantation alone (ITA), while 5 patients received islet transplantation after previous solid organ transplantation. For the group receiving 2 ITA, Kaplan-Meier estimates show an insulin independence of 20% more than 4 years after their last transplantation...
November 16, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27862340/everolimus-with-early-withdrawal-or-reduced-dose-calcineurin-inhibitors-improves-renal-function-in-liver-transplant-recipients-a-systematic-review-and-meta-analysis
#7
Michael Lin, Sahil Mittal, Farhad Sahebjam, Abbas Rana, Gagan K Sood
Calcineurin inhibitors (CNI) are the mainstay of immunosuppression after liver transplantation (LT), but CNIs are associated with significant nephrotoxicity. Recently, mTOR inhibitors such as sirolimus and everolimus (EVR) have been used with or without CNIs in LT recipients for their renal-sparing effect. We conducted a systematic review and meta-analysis of randomized controlled trials (RCT) that examined the effect of EVR with CNI minimization or withdrawal on renal function in LT recipients. RCT of primary adult LT recipients with baseline GFR >30 mL/min who received EVR with CNI minimization or withdrawal were included...
November 16, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27862317/impact-of-insurance-status-on-heart-transplant-waitlist-mortality-for-patients-with-left-ventricular-assist-devices
#8
Sitaramesh Emani, Dmitry Tumin, Randi E Foraker, Don Hayes, Sakima A Smith
OBJECTIVES: To test the hypotheses that receipt of Medicaid or Medicare (versus private insurance or self-pay) and low socioeconomic status (SES) leads to increased mortality and lower chances of transplantation among heart transplant (HTx) candidates with Bridge to Transplant Left Ventricular Assist Devices (BTT LVAD). BACKGROUND: Survival while awaiting HTx has improved with the use of BTT LVADs. However, it is unknown if benefits extend uniformly across patient groups based on insurance status...
November 16, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27859633/visceral-fat-is-strongly-associated-with-post-transplant-diabetes-mellitus-and-glucose-metabolism-one-year-after-kidney-transplantation
#9
Marit Elizabeth von Düring, Trond Jenssen, Jens Bollerslev, Anders Åsberg, Kristin Godang, Anders Hartmann
Body composition after kidney transplantation is linked to glucose metabolism, and impaired glucose metabolism is associated with increased risk of cardiovascular events and death. One year after transplantation we examined 150 patients for new-onset diabetes performing OGTTs and body composition measurements including visceral adipose tissue (VAT) content from dual-energy X-ray absorptiometry scans. We found that glucose metabolism was generally improved and that the levels of VAT and percentage VAT of total body fat mass (VAT%totBFM ) were lowest in those with normal glucose tolerance and highest in those with post transplant diabetes mellitus...
November 16, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27859626/depressive-symptoms-and-early-mortality-following-lung-transplantation-a-pilot-study
#10
P J Smith, J A Blumenthal, L D Snyder, J P Mathew, M Durheim, B M Hoffman, S Rivelli, S M Palmer
Impaired psychological function is common among lung transplant candidates and may affect clinical outcomes following transplantation. Although numerous studies have examined the relationship between pre-transplant depression, quality of life (QoL), and post-transplant outcomes, few have examined the relationship between depression and QoL shortly following transplantation and subsequent clinical outcomes. We therefore examined the association between depression, QoL, and short-term mortality in a consecutive series of lung transplant recipients METHODS: Depression (Patient Health Questionnaire-9; Hospital Anxiety and Depression Scale; Centers for Epidemiologic Studies Depression Scale) and QoL (UCSD Shortness of Breath Questionnaire; Pulmonary Quality of Life Scale) were assessed prior to transplantation (median 0...
November 16, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27859621/direct-oral-anticoagulant-considerations-in-solid-organ-transplantation-a-review
#11
REVIEW
David M Salerno, Demetra Tsapepas, Apostolos Papachristos, Jae-Hyung Chang, Spencer Martin, Mark A Hardy, Jaclyn McKeen
For more than sixty years, warfarin was the only oral anticoagulation agent available for use in the United States. In many recent clinical trials, several direct oral anticoagulants (DOACs) demonstrated similar efficacy with an equal or superior safety profile; with some other notable benefits. The DOACs have lower inter- and intra-patient variability, much shorter half-lives, and less known drug-drug and drug-food interactions as compared to warfarin. Despite these demonstrated benefits, the use of DOACs have not gained uniform acceptance because of lack of supportive data in special patient populations, including recipients of solid organ transplants maintained on immunosuppression...
November 16, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27859613/serial-measurement-of-presepsin-procalcitonin-and-crp-in-the-early-postoperative-period-and-the-response-to-antithymocyte-globulin-administration-after-heart-transplantation
#12
Janka Franeková, Peter Sečník, Petra Lavríková, Zdenek Kubíček, Lenka Hošková, Eva Kieslichová, Antonín Jabor
Differentiation between systemic inflammatory response syndrome (SIRS) and sepsis in surgical patients is of crucial significance. Procalcitonin (PCT) and C-reactive protein (CRP) are widely used biomarkers, but PCT becomes compromised after antithymocyte globulin (ATG) administration, and CRP exhibits limited specificity. Presepsin has been suggested as an alternative biomarker of sepsis. This study aims to demonstrate the role of presepsin in patients after heart transplantation (HTx). Plasma presepsin, PCT and CRP were measured in 107 patients serially for up to 10 days following HTx...
November 16, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27865004/long-term-effects-of-high-intensity-interval-training-in-heart-transplant-recipients-a-5-year-follow-up-study-of-a-randomized-controlled-trial
#13
Marianne Yardley, Lars Gullestad, Bjørn Bendz, Elisabeth Bjørkelund, Katrine Rolid, Satish Arora, Kari Nytrøen
BACKGROUND: Previously studies have demonstrated that high-intensity interval training(HIT) is superior to moderate-continuous exercise in general and in cardiovascular diseases. Recently we also found HIT safe and efficient after heart transplantation(HTx). This study reports the 5-year long-term effects. DESIGN AND METHODS: Forty-one HTx-patients who had completed the previous 12-month randomized controlled trial, comparing HIT-intervention with usual care, were eligible...
November 12, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27801541/leishmaniasis-in-solid-organ-and-hematopoietic-stem-cell-transplant-recipients
#14
REVIEW
Kiran Gajurel, Reshika Dhakal, Stan Deresinski
Leishmaniasis occurs in <1% of solid organ and hematopoietic stem cell transplant (SOT, HSCT) recipients in endemic countries in which transplants are performed. Visceral leishmaniasis (VL) makes up the bulk of reported cases. The onset generally occurs months after transplantation and the mode of acquisition is often impossible to determine, but de novo vector-borne infection and reactivation of inapparent infection are thought to be the principal means. The potential role of clinically inapparent donor infection is uncertain and screening is not currently recommended, nor is it recommended for recipients from endemic areas, some of whom may have detectable circulating protozoan nucleic acid...
November 1, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27801526/longitudinal-assessment-of-cardiac-morphology-and-function-following-kidney-transplantation
#15
Clark Kensinger, Antonio Hernandez, Aihua Bian, Meagan Fairchild, Guanhua Chen, Loren Lipworth, T Alp Ikizler, Kelly A Birdwell
BACKGROUND: Abnormal cardiac morphology is a risk factor for cardiovascular complications in kidney transplant patients. A supraphysiologic level of fibroblast growth factor 23 (FGF-23) has been associated with myocardial hypertrophy in this patient population. Our aim was to evaluate the change in cardiac morphology and function following kidney transplantation and to evaluate the association between the change in FGF-23 concentrations and cardiac morphology. METHODS: We performed a longitudinal, prospective cohort study of 143 kidney transplant recipients (73% male, 75% white) measuring left ventricular (LV) mass index, left atrial (LA) volume index, and ejection fraction (EF) by echocardiography at months 1, 12, and 24 post-transplant...
November 1, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27801525/complement-c3f-allotype-synthesized-by-liver-recipient-modifies-transplantation-outcome-independently-from-donor-hepatic-c3
#16
Diana María Valero-Hervás, Elena Sánchez-Zapardiel, María José Castro, Fernando Gallego-Bustos, Félix Cambra, Iago Justo, Rocío Laguna-Goya, Carlos Jiménez-Romero, Enrique Moreno, Francisco López-Medrano, Rafael San Juan, Mario Fernández-Ruiz, José María Aguado, Estela Paz-Artal
Complement component 3 (C3) presents both slow (C3S) and fast (C3F) variants, which can be locally-produced and activated by immune system cells. We studied C3 recipient variants in 483 liver transplant patients by RT-PCR-HRM to determine their effect on graft outcome during the first year post-transplantation. Allograft survival was significantly decreased in C3FF recipients (C3SS 95% vs. C3FS 91% vs. C3FF 83%; p=0.01) or C3F allele carriers (C3F-absence 95% vs. C3F-presence 90%, p=0.02). C3FF genotype or presence of C3F allele independently increased risk for allograft loss (OR: 2...
November 1, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27801506/impact-of-acute-kidney-injury-following-liver-transplantation-on-long-term-outcomes
#17
Emilie Trinh, Ahsan Alam, Jean Tchervenkov, Marcelo Cantarovich
BACKGROUND: The incidence of acute kidney injury (AKI) after liver transplantation (LTx) ranges from 17% to 94%. AKI is associated with prolonged hospitalization and increased early mortality. In our cohort study, we examined the impact of AKI on long-term patient survival and on the incidence of stage 4-5 chronic kidney disease (CKD). METHODS: We studied 491 LTx recipients at a single center between 1990 and 2012. We identified 278 pts (56.6%) with AKI defined as either an increase in serum creatinine (SCr) ≥26...
November 1, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27801505/role-of-inferior-vena-cava-filters-in-transplant-patients
#18
Joshua D Dowell, Jordan Castle, Jesse Spinner, Sylvester Black
PURPOSE: This study evaluates the selection, use, and risks of permanent and retrievable inferior vena cava filters (IVCFs) in patients who have undergone organ transplantation. MATERIALS AND METHODS: Single center retrospective review of 35 patients who had an IVCF placed following organ transplantation. Patient demographics, IVCF indication and eligibility for retrieval were reviewed. Computed tomography (CT) studies showing the filter (n=22) were evaluated independently for IVCF adverse effects...
November 1, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27740731/return-to-normal-activities-and-work-after-living-donor-laparoscopic-nephrectomy
#19
D Larson, C Jacobs, D Berglund, J Wiseman, C Garvey, K Gillingham, H N Ibrahim, A J Matas
Transplant programs inform potential donors that they should be able to return to normal activities within ~2 weeks and to work by 6 weeks after laparoscopic nephrectomy. We studied actual time. Between 10/2004 - 9/2014, 911 donors having laparoscopic nephrectomy were surveyed 6 months post-donation. Surveys asked questions specific to their recovery experience, including time to return to normal activities and work; and a description of their recovery time relative to pre-donation expectations. Of the 911, 646 (71%) responded: mean age at donation was 43...
October 14, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27726195/the-use-of-robotic-surgery-in-abdominal-organ-transplantation-a-literature-review
#20
REVIEW
Giovanni B Levi Sandri, Edoardo de Werra, Gianluca Mascianà, Francesco Guerra, Gabriele Spoletini, Quirino Lai
Minimally invasive surgical approaches in transplantation are gaining increasing interest, and many centers are reporting their, mainly laparoscopic, experiences. Robotic surgery (RS) has some hypothetical advantages over traditional laparoscopy and has been successfully applied, although infrequently to organ transplantation. Our goal was to review and critique the publications reporting RS use in organ transplantation. Most of the RS experience has been with living renal donor organ procurement and, to a lesser extent, with RS procedures in the transplant recipient...
October 11, 2016: Clinical Transplantation
journal
journal
20084
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"