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Clinical Nuclear Medicine

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https://www.readbyqxmd.com/read/29036003/68ga-prostate-specific-membrane-antigen-avid-tubercular-lesions-mimicking-prostate-cancer-metastasis-on-simultaneous-prostate-specific-membrane-antigen-pet-mri
#1
Aashim Ahuja, Sangeeta Taneja, Kiran Thorat, Amarnath Jena
Ga-prostate-specific membrane antigen (PSMA) has gained increasing interest as a target molecule in imaging of prostate cancer because of its selective overexpression in local prostate cancer lesions and metastasis. We report a case of a 62-year-old man with raised serum prostate-specific antigen levels who presented for Ga-PSMA HBED-CC simultaneous PET/MRI for prostate cancer evaluation. A PSMA-nonavid PI-RADS 5 (Prostate Imaging-Reporting and Data System) lesion was confirmed as adenocarcinoma on histopathology...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29036002/multimodal-imaging-in-klippel-tr%C3%A3-naunay-weber-syndrome-clinical-photography-computed-tomoangiography-infrared-thermography-and-99mtc-phytate-lymphoscintigraphy
#2
Su Wan Kim, Heesung Song
We report the case of a 19-year-old man who presented with a 12-year history of progressive fatigue, feeling hot, excessive sweating, and numbness in the left arm. He had undergone multimodal imaging and was diagnosed as having Klippel-Trénaunay-Weber syndrome (KTWS). This is a rare congenital disease, defined by combinations of nevus flammeus, venous and lymphatic malformation, and hypertrophy of the affected limbs. Lower extremities are affected mostly. Conventional modalities for evaluating KTWS are ultrasonography, CT, MRI, lymphoscintigraphy, and angiography...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29036001/atlas-of-extraosseous-findings-detected-by-18f-naf-pet-ct-bone-scan
#3
Gregory J Woodhead, Ryan J Avery, Phillip H Kuo
F-NaF PET/CT is an evolving technique that provides high sensitivity for detection of osseous metastases. In addition to detecting pathological osseous lesions, F uptake is occasionally detected in extraosseous lesions. However, reporting of extraosseous uptake in the literature is limited, and the increasing use of F-NaF PET/CT dictates that interpreting physicians learn to recognize extraosseous findings. An atlas of extraosseous findings detected by F-NaF PET/CT is presented, which includes cases under 2 broad categories: nonneoplastic and neoplastic...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29036000/unilateral-submandibular-gland-atrophy-and-sialolithiasis-diagnosed-on-99mtc-mibi-spect-ct-in-a-patient-with-primary-hyperparathyroidism
#4
Puskar Pattanayak, Prasanna Santhanam, Mehrbod Som Javadi, Lilja B Solnes, Steven P Rowe
A variety of sequelae of elevated calcium levels are encountered in patients with underlying primary hyperparathyroidism, including stone formation such as calculi in the urinary tract and sialoliths in the salivary glands and ducts. We present a case of a 54-year-old woman with fatigue, myalgia, and poor concentration who was found to have hypercalcemia (corrected calcium, 11.2 mg/dL) and elevated parathyroid hormone level (112 pg/mL), laboratory values consistent with primary hyperparathyroidism. She underwent evaluation with a Tc-MIBI parathyroid SPECT scan that included x-ray CT acquisitions for anatomical localization and attenuation correction...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29035999/effects-on-18f-fdg-pet-ct-brain-glucose-metabolism-in-rectal-cancer-patients-undergoing-neoadjuvant-chemotherapy
#5
Alexei M C Machado, Theara C Fagundes, Arnoldo Mafra, Rodrigo G Silva, Ana Carolina G Castro, Marcelo Mamede
PURPOSE: Retrospective study of the effects of anticancer treatment on the brain metabolism of patients diagnosed with rectal cancer based on a large and homogeneous sample of 40 paired F-FDG PET/CT volumes taken from 20 patients. The results are compared to the ones presented by related works to help elucidating the mechanisms of neurotoxicity associated to a decrease in memory, learning and motor skills. PATIENTS AND METHODS: Twenty patients with rectal adenocarcinoma were scanned before and after neoadjuvant chemoradiation based exclusively on 5-fluorouracil and leucovorin...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29035998/uterine-metastasis-from-gastric-adenocarcinoma-masquerading-as-physiologic-endometrial-uptake-in-fdg-pet-ct
#6
Yutang Yao, Minggang Su, Xiaohong Ou, Yangmei Shen
A 44-year-old woman with newly diagnosed gastric adenocarcinoma by gastroscopy underwent F-FDG PET/CT to evaluate possible metastasis. The images demonstrated intense activity in the region of uterine corpus, as well as greater gastric curvature. Physiologic uptake of endometrium was initially suspected, given the rarity with which extragenital cancers metastasize to the uterus. Ultimately, the endometrium proved to be mucinous adenocarcinoma of gastric origin based on its shared histological features and compatible immunostaining profile...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29035997/stewart-treves-syndrome-on-the-lower-extremity-associated-to-idiopathic-chronic-lymphedema-visualized-on-fdg-pet-ct
#7
Jane Maestri Brittain, Tine Nymark, Malene Grubbe Hildebrandt, Dorrit Hovgaard, Kim Francis Andersen
Angiosarcomas are highly malignant and rare tumors of vascular or lymphatic endothelial cell origin with a poor prognosis. Lymphangiosarcoma associated with chronic lymphedema is known as Stewart-Treves syndrome. Stewart-Treves syndrome is primarily described in patients with lymphedema of an upper extremity occurring after breast cancer surgery including radical axillary lymph node dissection and subsequent radiotherapy. It is rarely described in the presence of idiopathic chronic lymphedema of the lower extremities...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29035996/radioguided-occult-lesion-localization-technical-procedures-and-clinical-applications
#8
Gianpiero Manca, Sara Mazzarri, Domenico Rubello, Elisa Tardelli, Roberto C Delgado-Bolton, Francesco Giammarile, Manuela Roncella, Duccio Volterrani, Patrick M Colletti
PURPOSE: Regarding radioguided surgery, the concept of "radioguided occult lesion localization" (ROLL) is based on both preoperative interventional imaging and intraoperative radioguided detection of a clinically occult neoplastic lesion. METHODS: This methodology consists in the direct administration into the lesion of Tc-macroaggregated human albumin formed by relatively large particles retained at the injection site, which direct radioguided excisional biopsy...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29035995/internal-auditory-canal-tumor-as-an-incidental-finding-on-a-choline-pet-ct-scan-in-a-prostate-cancer-patient
#9
Julia Malamitsi, Roxanni Efthymiadou, Theodore Pipikos, Fani Vlachou, Vassilis Prassopoulos
An 84-year-old man with a history of prostate cancer, treated with radiotherapy, presented with an increase in PSA levels. F-choline PET/CT showed foci of increased choline uptake in L4 and L5 vertebrae, suggestive of bone metastases and another focus in the right cerebellopontine angle. A brain MRI revealed a focus of intense contrast enhancement in the same region, consistent with an acoustic neuroma.
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29035994/prostate-specific-membrane-antigen-in-low-grade-fibromatosis
#10
Ramin Akbarian Aghdam, Masoumeh Hakiminejad, Hamidreza Hashemifard, Azadeh Rakhshan, Elahe Pirayesh
We report a case of fibromatosis demonstrating prostate-specific membrane antigen (PSMA)-positive scan. A 76-year-old man was under assessment because of rising prostate-specific antigen level. Bone scan showed abnormal soft tissue uptake of Tc-MDP adjacent to the right scapula, compatible with a mass in MRI, thereafter. Because of the unavailability of Ga-PSMA scan in our department and also high cost in other centers, the patient underwent Lu-PSMA for more assessment, which revealed PSMA-avid mass. Pathologic examination confirmed the diagnosis of low-grade fibromatosis...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29035993/uncommon-metastasis-to-the-pancreas-from-adenocarcinoma-of-the-cervix-detected-on-surveillance-18f-fdg-pet-ct-imaging
#11
Sonia Mahajan, Neeta Pandit-Taskar
F-FDG PET/CT is a sensitive noninvasive imaging tool for assessment of recurrent disease in patients with carcinoma cervix. Its role in early detection of recurrences especially in asymptomatic patients has been demonstrated well in literature. Metastatic involvement of the pancreas in patients with adenocarcinoma of the cervix is a rare occurrence, reported only few times in literature, and is predominantly documented to be associated with uncommon histopathologies such as neuroendocrine and small cell carcinoma...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29035992/18f-faza-pet-ct-hypoxia-imaging-of-high-grade-glioma-before-and-after-radiotherapy
#12
Paola Mapelli, Flavia Zerbetto, Elena Incerti, Gian Marco Conte, Valentino Bettinardi, Federico Fallanca, Nicoletta Anzalone, Nadia Di Muzio, Luigi Gianolli, Maria Picchio
A 57 year-old man underwent MRI with dynamic susceptibility contrast and dynamic contrast-enhanced perfusion for neurological symptoms suggesting the diagnosis of high-grade glioma. A F-FAZA PET/CT was performed because of the enrollment in a prospective clinical trial. Subsequent radiotherapy treatment has been planned based on conventional imaging; moreover, a F-FAZA PET/CT-guided treatment planning highlighting hypoxic regions has been simulated. After radiotherapy treatment, the man underwent MRI and F-FAZA PET/CT, showing partial response...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29035991/myocardial-perfusion-spect-and-cardiac-mr-correlative-imaging
#13
Ashley E Prosper, Patrick M Colletti
An institutional review board-approved retrospective review of 55 patients who received cardiac MRI within 1 year of myocardial SPECT was performed. Forty-nine demonstrated myocardial infarction by MRI. MRI and SPECT agreed in all but 1 case, where SPECT preceded MRI by 97 days. Three cases are presented here: 2 demonstrating congruent MRI and SPECT changes in a vascular distribution status post infarction and a third with a nonvascular pattern of abnormalities related to left ventricular aneurysm in cardiac sarcoidosis...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29035990/interruption-of-the-inferior-vena-cava-with-azygos-continuation
#14
Chien-Wei Kuo, Nan-Jing Peng, Yu-Li Chiu
This report describes a 19-year-old man with interruption of the inferior vena cava with azygos continuation. Both radionuclide venography and MRI clearly showed venous return of the lower limbs through prominent collateral systems.
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28945624/quality-and-safety-in-health-care-part-xxxiii-transcatheter-mitral-valve-therapy
#15
Jay A Harolds
The transcatheter mitral valve procedure with the MitraClip device has been clinically available in much of Europe since 2008. In 2013, the Food and Drug Administration permitted MitraClip procedures to be done commercially for those patients with primary severe mitral regurgitation who were not surgical candidates. The COAPT trial is designed to see if the MitraClip procedure should be approved in the United States for those with secondary mitral regurgitation, although it has been used for that purpose in much of Europe for years...
September 22, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28926345/reviewer-awards-and-acknowledgements-editors-recognition-awards-for-distinction-in-reviewing-in-2016
#16
Patrick M Colletti
No abstract text is available yet for this article.
September 18, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28922192/differentiation-of-malignant-thrombus-from-bland-thrombus-of-the-portal-vein-in-patient-with-hepatocellular-carcinoma-on-18f-fdg-pet-ct
#17
Krishan Kant Agarwal, Dipalkumar Shah, Neha Shah, Manas Mayank
Hepatocellular carcinoma carries a high risk of invasion of the portal vein. Neoplastic and bland portal vein thrombi discrimination is of great clinical significance for determining the therapeutic approach, predicting survival, and assessing candidates for liver transplantation. F-FDG PET/CT may be helpful in discriminating between malignant and portal vein thrombi. We present the case of a 61-year old man who presented with hepatocellular carcinoma with portal vein involvement. F-FDG PET/CT has a role in differentiating malignant from benign portal vein thrombosis...
September 15, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28922191/acr-spr-str-practice-parameter-for-the-performance-of-cardiac-positron-emission-tomography-computed-tomography-pet-ct-imaging
#18
Rathan M Subramaniam, Warren R Janowitz, Geoffrey B Johnson, Martin A Lodge, Marguerite T Parisi, Mark R Ferguson, Jeffrey C Hellinger, Gregory W Gladish, Narainder K Gupta
This clinical practice parameter has been developed collaboratively by the American College of Radiology (ACR), the Society for Pediatric Radiology (SPR), and the Society of Thoracic Radiology (STR). This document is intended to act as a guide for physicians performing and interpreting positron emission tomography-computed tomography (PET/CT) of cardiac diseases in adults and children. The primary value of cardiac PET/CT imaging include evaluation of perfusion, function, viability, inflammation, anatomy, and risk stratification for cardiac-related events such as myocardial infarction and death...
September 15, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28922189/acr-acnm-practice-parameter-for-the-performance-of-dopamine-transporter-dat-single-photon-emission-computed-tomography-spect-imaging-for-movement-disorders
#19
Rathan M Subramaniam, Kirk A Frey, Christopher H Hunt, Gustavo A Mercier, Lilja B Solnes, Patrick M Colletti, Yang Lu, Bital Savir-Baruch, Hadyn T Williams
This American College of Radiology and American College of Nuclear Medicine joint clinical practice parameter is for performance of dopamine transporter single photon emission computed tomography (SPECT) imaging, for patients with movement disorders. Parkinsonian syndrome (PS) consists of a group of neurodegenerative diseases including Parkinson disease (PD), progressive supranuclear palsy (PSP), multiple system atrophy (MSA), corticobasal degeneration (CBD), and dementia with Lewy bodies (DLB). Accurate diagnosis of PS is critical for clinical management...
September 15, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28902738/false-positive-pancreatic-uptake-detected-on-68ga-psma-pet-ct-a-priority-changing-incidental-finding-while-assessing-the-need-for-a-prostate-biopsy
#20
Mehmet Onur Demirkol, Murat Can Kiremit, Omer Acar, Alan Alper Sag, Yersu Kapran
A 72-year-old man underwent Ga-PSMA PET/CT because of an elevated prostate-specific antigen level despite prior prostatectomy. Besides low-intensity prostatic PSMA reactivities, a faintly PSMA-positive lesion in the pancreatic corpus drew attention, which seemed suggestive of a primary pancreatic cancer on the subsequent MRI and therefore had to be excised. The final diagnosis was pT3 low-grade neuroendocrine tumor. PSMA-positive incidentalomas, detected on Ga-PSMA PET/CT, can reveal more clinically significant extraprostatic disorders...
September 11, 2017: Clinical Nuclear Medicine
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