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Clinical Journal of Pain

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https://www.readbyqxmd.com/read/28328700/lumbar-tactile-acuity-in-patients-with-low-back-pain-and-healthy-controls-systematic-review-and-meta-analysis
#1
Wacław Adamczyk, Kerstin Luedtke, Edward Saulicz
OBJECTIVE: Diminished tactile acuity in chronic non-neuropathic pain syndromes has been attributed to central pain processing and cortical reorganization. The latter was recently targeted in clinical trials that demonstrated no clear advantages over traditional approaches for the reduction of nonspecific low back pain (LBP). The aim of this systematic review and meta-analysis was to summarize the current evidence on tactile acuity in LBP and pain-free controls. METHODS: Six databases were independently searched by 2 researchers...
March 21, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28328699/a-mindfulness-program-adapted-for-adolescents-with-chronic-pain-feasibility-acceptability-and-initial-outcomes
#2
Danielle A Ruskin, Michelle M Gagnon, Sara A Kohut, Jennifer N Stinson, Kathryn S Walker
OBJECTIVES: Pediatric chronic pain is a major health issue which can lead to significant interference in daily functioning. Mindfulness-based interventions (MBI's), which emphasize acceptance rather than control of pain, have gained increasing attention as a viable treatment option among adults with chronic pain. The effectiveness of MBIs for chronic pain in pediatric populations remains largely unknown. This prospective pre-post interventional study was conducted to examine the feasibility, acceptability, and initial effectiveness of an 8-week group MBI for adolescents (MBI-A) with chronic pain...
March 21, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28328698/reduced-sufentanil-doses-are-effective-for-postoperative-analgesia-after-ductal-closure-in-extremely-premature-infants-a-10-years-retrospective-cohort-study
#3
Yohan Soreze, Etienne Audureau, Fabrice Decobert, Olivier Jaby, Sabine Blary, Claude Danan, Xavier Durrmeyer
OBJECTIVES: The objective of the study was to assess the efficacy of reduced sufentanil doses for postoperative analgesia following surgical ductal closure in extremely premature infants. METHODS: This was a retrospective, single-center, cohort study comparing 2 sufentanil dosing regimens used between 2001 and 2010 and included all infants born at <28 weeks of gestation with surgical ductal closure. Sufentanil doses were reduced in 2007 as a standard of care...
March 21, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28328697/the-fear-avoidance-components-scale-facs-responsiveness-to-functional-restoration-treatment-in-a-chronic-musculoskeletal-pain-disorder-cmpd-population
#4
Randy Neblett, Tom G Mayer, Mark J Williams, Sali Asih, Antonio I Cuesta-Vargas, Meredith M Hartzell, Robert J Gatchel
OBJECTIVES: To assess the clinical validity and factor structure of the Fear-Avoidance Components Scale (FACS), a new fear-avoidance (FA) measure. METHODS: In this study, 426 chronic musculoskeletal pain disorder (CMPD) patients were admitted to a functional restoration program (FRP). They were categorized into five FACS severity levels, from Subclinical to Extreme, at admission, and again at discharge. Associations with objective lifting performance and other patient-reported psychosocial measures were determined at admission and discharge, and objective work outcomes for this predominantly disabled cohort, were assessed one-year later...
March 21, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28277434/age-interactions-on-pain-sensitization-in-patients-with-severe-knee-osteoarthritis-and-controls
#5
Kristian Kjær Petersen, Lars Arendt-Nielsen, Sara Finocchietti, Rogerio Pessoto Hirata, Ole Simonsen, Mogens Berg Laursen, Thomas Graven-Nielsen
OBJECTIVES: Widespread pressure hyperalgesia, facilitated temporal summation of pain (TSP), and impaired conditioned pain modulation (CPM) have been found in knee osteoarthritis (KOA) patients compared with controls and these parameters have further been suggested to be altered in the elderly. This study investigated the influence of age on pressure hyperalgesia, TSP, and CPM in patients with KOA and controls. METHODS: One-hundred-thirty-three severe KOA patients and 50 age and sex-matched asymptomatic controls were assessed by cuff algometry and handheld pressure algometry...
March 8, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28272120/the-impact-of-serum-drug-concentration-on-the-efficacy-of-imipramine-pregabalin-and-their-combination-in-painful-polyneuropathy
#6
Søren H Sindrup, Jakob V Holbech, Flemming W Bach, Nanna B Finnerup, Kim Brøsen, Troels S Jensen
OBJECTIVE: The serum concentration-effect relation was explored for first line drugs in neuropathic pain and aimed to determine if efficacy could be increased. METHODS: Data from a randomized, placebo-controlled, cross-over trial on imipramine, pregabalin and their combination in painful polyneuropathy were used. Treatment periods were of 4 weeks' duration, outcome was the weekly median of daily pain rated by a 0-10 numeric scale, and drug concentrations were determined by high-performance liquid chromatography...
March 7, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28272119/obesity-moderates-the-effects-of-motivational-interviewing-treatment-outcomes-in-fibromyalgia
#7
Anthony S Kaleth, James E Slaven, Dennis C Ang
OBJECTIVE: Obesity is a common comorbid condition among patients with fibromyalgia (FM). Our objective was to assess if obesity moderates the treatment benefits of exercise-based motivational interviewing (MI) for FM. METHODS: This is a secondary data analysis of a completed clinical trial of 198 FM patients who were randomized to receive either MI or attention control (AC). Using body mass index (BMI) to divide participants into obese (BMI ≥30 kg/m) and non-obese (BMI <30 kg m) groups, mixed linear models were used to determine interaction between treatment arms and obesity status with regards to the primary outcome of global FM symptom severity (Fibromyalgia Impact Questionnaire, FIQ)...
March 7, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28272118/common-pediatric-pain-disorders-and-their-clinical-associations
#8
Theresa Donnelly, Aneeka Bott, Minh Bui, Shuxiang Goh, Tiina Jaaniste, Cindy Chapman, Matthew Crawford, John L Hopper, David Champion
BACKGROUND: Common childhood pain conditions (non-migraine headache, migraine, recurrent abdominal pain, growing pains, low back pain) and persistent pains are often associated with each other and have significant implications in later life. Emerging evidence suggests additional associations between these pain conditions and restless legs syndrome, iron deficiency, anxiety and depression. The aim of this cross-sectional study in pediatric twin individuals and their siblings was to investigate these associations...
March 7, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28272117/altered-functional-connectivity-in-sickle-cell-disease-exists-at-rest-and-during-acute-pain-challenge
#9
William T Zempsky, Michael C Stevens, James P Santanelli, Alexandra M Gaynor, Sabin Khadka
OBJECTIVES: Sickle cell disease (SCD) is a chronic pain disorder in which abnormally shaped red blood cells obstruct microcirculation causing ischemia and pain. The lack of SCD responsiveness to analgesics has led many to propose that nociceptive neural systems engaged when detecting pain become sensitized, resulting in an enhancement of pain response. METHODS: SCD patients and healthy controls were exposed to a painful stimuli of varying intensity using a pressure algometer and underwent several neuroimaging tasks...
March 7, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28244945/the-associated-factors-and-clinical-features-of-neuropathic-pain-after-brachial-plexus-injuries-a-cross-sectional-study
#10
Yingjie Zhou, Peixi Liu, Jing Rui, Xin Zhao, Jie Lao
INTRODUCTION: Neuropathic pain in patients with brachial plexus injuries brings complicated obstacles to the treatment and recovery for both surgeons and patients. OBJECTIVES: The clinical features of neuropathic pain, including pain intensity, type and time phase, need to be investigated. Moreover, possible associated factors need to be explored. METHODS: A cross-sectional study containing 77 participants was conducted. Their baseline information and injury-related conditions were collected...
February 27, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28244944/goals-of-chronic-pain-management-do-patients-and-primary-care-physicians-agree-and-does-it-matter
#11
Stephen G Henry, Robert A Bell, Joshua J Fenton, Richard L Kravitz
OBJECTIVE: Assess patient-physician agreement on management goals for chronic musculoskeletal pain and its associations with patient and physician visit experiences. MATERIALS AND METHODS: Previsit and postvisit questionnaires for 87 primary care visits involved patients taking opioids for chronic musculoskeletal pain and primary care residents. After each visit, patients and physicians independently ranked 5 pain treatment goals from most to least important. RESULTS: In total, 48% of patients ranked reducing pain intensity as their top priority, whereas 22% ranked finding a diagnosis as most important...
February 27, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28244943/mixed-pain-can-be-discerned-in-the-primary-care-and-orthopedics-settings-in-spain-a-large-cross-sectional-study
#12
Pedro J Ibor, Isabel Sánchez-Magro, Jesús Villoria, Ana Leal, Ana Esquivias
OBJECTIVES: To assess the value of the concept of mixed pain by investigating its acceptance and interpretation by health care professionals and the differential characteristics in patients with mixed pain. MATERIALS AND METHODS: Data from 5024 patients suffering pain from 551 sites in Primary Care and Orthopedics settings were analyzed in this cross-sectional study. Pain characteristics, other factors influencing pain, health care-related data and health-related quality of life were summarized and compared among 3 groups of patients according to the type of pain (nociceptive, neuropathic, or mixed), as assigned by the investigators after considering the pathophysiological mechanisms involved...
February 27, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28234752/gray-matter-abnormalities-associated-with-chronic-back-pain-a-meta-analysis-of-voxel-based-morphometric-studies
#13
CongHu Yuan, HaiCun Shi, PingLei Pan, ZhenYu Dai, JianGuo Zhong, HaiRong Ma, LiQin Sheng
BACKGROUND: Studies employing voxel-based morphometry (VBM) have reported inconsistent findings on the association of gray matter (GM) abnormalities with chronic back pain (CBP). We therefore performed a meta-analysis of available studies to identify the most consistent GM regions associated with CBP. METHODS: The PubMed, Embase, and Web of Science databases were searched from January 2000 to 29 May 2016. Comprehensive meta-analyses of whole-brain VBM studies to identify the most robust GM abnormalities in CBP were conducted using the Seed-based d Mapping software package...
February 23, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28177940/emergency-department-pain-management-in-children-with-appendicitis-in-a-bi-ethnic-population
#14
Ron Jacob, Baruch Krauss, Gal Twito, Ronit Leiba, Itai Shavit
OBJECTIVES: Our goal was to examine factors associated with the administration of ED analgesia (any analgesia, opioid analgesia) in patients with acute appendicitis in a tertiary children's hospital in Israel, and to examine ethnic differences. METHODS: A retrospective cohort study of children evaluated in the ED, who had ICD-9 diagnosis of acute appendicitis. Regression analysis was used to test the effect of multiple variables on the provision of analgesia. Medications were administered according to a nurse-driven pain protocol...
February 7, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28177939/review-of-the-evidence-on-the-efficacy-of-dexamethasone-on-postoperative-analgesic-consumption
#15
Chrysanthi Batistaki, Evagelia Kaminiotis, Thomas Papadimos, Georgia Kostopanagiotou
OBJECTIVES: The effect of dexamethasone on analgesic consumption has not been adequately studied. The aim of this review was to investigate recent literature regarding the possible effect of dexamethasone on postoperative analgesic consumption. METHODS: Critical review of randomized trials, and prospective consecutive studies, investigating the post-operative analgesic effect of dexamethasone was performed. Only studies published during 2006-2015 were included. RESULTS: Forty-one studies met the inclusion criteria; 33 in adults and 8 in children (9 in general surgery, 8 in gynecological/breast surgery, 8 in orthopedic/spinal surgery, 8 in head/neck surgery, 7 in children's tonsillectomy, and 1 in children's orchiopexy)...
February 7, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28157138/expectancy-reduces-symptoms-but-not-functional-impairment-following-exercise-induced-musculoskeletal-injury
#16
William C Hedderson, Geoffrey C Dover, Steven Z George, Joshua A Crow, Paul A Borsa
OBJECTIVES: To quantify the extent to which the participant-provider interaction influences the response to sham treatment following exercised-induced acute musculoskeletal pain. METHODS: Forty participants between the ages of 18 and 35 volunteered for the study. Participants came to the laboratory for three test sessions 48-hours apart (Day 1, 3 and 5). During the initial session, baseline measures were assessed and participants underwent a fatigue protocol for the biceps brachii...
February 2, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28145912/possible-opioid-shopping-and-its-correlates
#17
Alexander M Walker, Lisa B Weatherby, M Soledad Cepeda, Daniel Bradford, Yingli Yuan
BACKGROUND: We created an operational definition of possible opioid shopping in US commercial health insurance data and examined its correlates. METHODS: The population consisted of 264,204 treatment courses in persons with a fill for an opioid or diuretic prescription in 2012 and a second within 18 months. We examined counts of prescribers and pharmacies and the numbers of fills and overlaps for ability to discriminate courses of opioids from diuretics, which were a negative control...
January 31, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28145911/chronic-pain-and-itch-are-common-morbid-sequelae-among-individuals-who-receive-tissue-autograft-after-major-thermal-burn-injury
#18
Matthew C Mauck, Jennifer Smith, Andrea Y Liu, Samuel W Jones, Jeffrey W Shupp, Marie A Villard, Felicia Williams, James Hwang, Rachel Karlnoski, David J Smith, Bruce A Cairns, Ronald C Kessler, Samuel A McLean
OBJECTIVE: Pain and itch symptoms are common after major thermal burn injury (MThBI)-requiring tissue autografting. To our knowledge, no prospective longitudinal studies have characterized pain and itch outcomes after tissue autografting and associations between and functional interference caused by such symptoms. MATERIALS AND METHODS: We prospectively evaluated burn graft site and tissue donor site pain and itch severity (0 to 10, numeric rating scale) over 1 year among a representative cohort of MThBI survivors (n=96) who received tissue autografting within 14 days of MThBI...
January 31, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28145910/evaluating-the-association-between-acute-and-chronic-pain-after-surgery-impact-of-pain-measurement-methods
#19
Ian Gilron, Elizabeth Vandenkerkhof, Joel Katz, Henrik Kehlet, Meg Carley
There is a need to predict chronic (≥3▒mo) postsurgical pain (CPSP). Acute (<7▒d) pain is a predictor, i.e. more severe pain associated with higher CPSP risk. However, reported associations vary widely. Using a systematic search, we examined associations between two acute pain measures (pain at rest [PAR] and movement-evoked pain [MEP]) and CPSP outcomes (considering severity vs. any "non-zero" pain only) in 22 studies. Seven studies reported the relationship between CPSP and both PAR and MEP. Of these, 2/7 reported no association, 3/7 reported significant associations for both PAR and MEP, 1/7 reported an association for PAR only and 1/7 reported an association for MEP only...
January 31, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28118255/smoking-may-increase-postoperative-opioid-consumption-in-patients-who-underwent-distal-gastrectomy-with-gastroduodenostomy-for-early-stomach-cancer-a-retrospective-analysis
#20
Doo Hwan Kim, Jun Young Park, Myong-Hwan Karm, Heon-Yong Bae, Jae-Young Lee, Ho Soo Ahn, Kunhee Lee, Jeong Gil Leem
OBJECTIVES: Although nicotine has an analgesic effect, the incidence and severity of chronic pain is higher in smokers than nonsmokers. Acute pain is more intense in smokers during the perioperative period. This study evaluated weather smokers require higher doses of opioid to reduce pain when they undergo surgery. METHODS: From October 2013 to September 2014, a retrospective review of 236 patients who had intravenous patient-controlled analgesia after distal gastrectomy with gastroduodenostomy was performed to analyze the difference in postoperative opioid requirements between smokers and nonsmokers...
January 23, 2017: Clinical Journal of Pain
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