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Clinical Journal of Pain

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https://www.readbyqxmd.com/read/29443723/neurophysiological-pain-education-for-patients-with-chronic-low-back-pain-a-systematic-review-and-meta-analysis
#1
Heidi Tegner, Pernille Frederiksen, Bente Appel Esbensen, Carsten Juhl
OBJECTIVE: To evaluate the effect of Neurophysiological Pain-Education (NPE) for patients with Chronic Low Back Pain (CLBP). METHODS: A systematic search was performed in six electronic databases. Eligible RCTs were those with at least 50 % of patients with CLBP and in which NPE was compared with no intervention or usual care. Methodological quality was assessed independently by two of the authors using the Cochrane Collaboration Risk of Bias Tool. The effect of NPE was summarized in a random effect meta-analysis for pain, disability and behavioral attitudes...
February 13, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29443722/characterizing-treatment-utilization-patterns-for-trigeminal-neuralgia-in-the-united-states
#2
Joanna M Zakrzewska, Ning Wu, John Y K Lee, Brian Werneburg, Deborah Hoffman, Ying Liu
BACKGROUND AND AIM: Trigeminal neuralgia (TN) is a rare orofacial disorder characterized by severe unilateral paroxysmal pain in the region of the fifth cranial nerve. Clinical guidelines recommend carbamazepine (only US Food and Drug Administration-approved drug for TN) and oxcarbazepine as first-line therapies. We utilized the US Truven Health MarketScan database to examine treatment patterns among patients with TN. METHODS: Included patients were aged ≥18 years, newly diagnosed with TN (≥2 TN diagnoses ≥14 days apart; no diagnosis in the prior year), continuously enrolled 1 year pre-index, with ≥3 years' follow-up post-index...
February 13, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29406367/opioid-use-during-pregnancy-observations-of-opioid-use-and-secular-trend-from-2006-to-2014-at-healthpartners-medical-group
#3
Thomas E Elliott, Caitlin K Frail, Pamala A Pawloski, Avis J Thomas, Ann M Werner, Rebecca C Rossom
OBJECTIVES: Determine the prevalence of opioid use before, during, and after pregnancy and describe its use based on patient-specific characteristics. Determine secular trend of opioid use 2006-2014. METHODS: Retrospective cohort study. A large Upper Midwest integrated healthcare system and insurer. Females age 10 to 50 years with a delivery diagnosis from July 1, 2006 through June 30, 2014. MAIN OUTCOME MEASURE: Prevalence of opioid use before, during, and after pregnancy; description of opioid use during these time periods...
February 5, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29406366/lack-of-prognostic-model-validation-in-low-back-pain-prediction-studies-a-systematic-review
#4
Greg McIntosh, Ivan Steenstra, Sheilah Hogg-Johnson, Tom Carter, Hamilton Hall
OBJECTIVE: To investigate the frequency with which prediction studies for low back pain outcomes utilize prospective methods of prognostic model validation. METHOD: Searches of Medline and Embase for terms "predict/predictor", "prognosis" or "prognostic factor". The search was limited to studies conducted in humans and reported in the English language. Included articles were all those published in two Spine specialty journals (Spine and The Spine Journal) over a 13 month period, January 2013 to January 2014...
February 5, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29406365/acute-pain-assessment-in-sedated-patients-in-the-post-anesthesia-care-unit
#5
Sherily Pereira-Morales, Carmen Mabel Arroyo-Novoa, Annete Wysocki, Lucille Sanzero Eller
CONTEXT: Acute postoperative pain remains inadequately assessed and managed. A valid instrument that assesses acute pain in sedated Post-Anesthesia Care Unit (PACU) patients is needed. OBJECTIVES: Two behavioral pain assessment instruments, the Non-Verbal Pain Scale Revised (NVPS-R) and Critical Care Pain Observation Tool (CPOT), were used to determine if these instruments adequately assess acute pain in the PACU. METHODS: A crossover study design was used...
February 5, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29319537/a-systematic-review-of-labour-pain-used-as-an-outcome-criterion-in-clinical-research
#6
Christian Dualé, Gaétan Breysse, Bruno Pereira
OBJECTIVES: Research on labour pain currently uses standard scores such as numerical scales as clinical outcomes, but no clear guidelines for such assessment have appeared since a review published in 1998. We wished to describe and estimate the quality of the methods used to assess and analyse such outcomes, in a systematic review of 215 comparative studies published since then, in 27 influential journals. METHODS: In addition to a complete description, we created for each study a composite "analysis quality score" (AQS) based on the methods of both measurement of pain/analgesia, and statistical analysis...
January 9, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29300197/effectiveness-of-sucrose-used-routinely-for-pain-relief-and-neonatal-clinical-risk-in-preterm-infants-a-nonrandomized-study
#7
Beatriz Oliveira Valeri, Cláudia Maria Gaspardo, Francisco Eulógio Martinez, Maria Beatriz Martins Linhares
BACKGROUND: Preterm infants (PI) requiring the Neonatal Intensive Care Unit (NICU) are exposed to early repetitive pain/distress. Little is known about how pain relief strategies interact with infants'clinical health status, such as severity of illness with pain responses. This study aimed to examine main and interactive effects of routine sucrose intervention and neonatal clinical risk (NCR) on biobehavioral pain reactivity-recovery in PI during painful blood collection procedures. METHODS: Very-low birthweight PI (n=104) were assigned to Low and High Clinical Risk Groups, according to the Clinical Risk Index for Babies...
January 3, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29298187/evaluating-differential-effects-of-specific-pain-dismissal-interactions-with-physicians
#8
Amy C Lang, Eva C Igler, Ellen K Defenderfer, Julia Uihlein, Chasity T Brimeyer, W Hobart Davies
OBJECTIVES: Over 40% of adolescents with chronic pain report experiencing pain dismissal, which is a response from another individual that is perceived as diminishing, denying, or disbelieving an individual's report of pain. Pain dismissal by physicians often leaves patients feeling discredited, which may discourage them from seeking and receiving proper treatment for their pain. The purpose of this study was to investigate how the four most commonly reported types of physician pain dismissal differentially affect individuals' reactions...
January 2, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29298186/evaluation-of-the-relative-abuse-of-an-oros%C3%A2-extended-release-hydromorphone-hci-product-results-from-three-post-market-surveillance-studies
#9
Stephen F Butler, Emily C McNaughton, Ryan A Black, Theresa A Cassidy
OBJECTIVE: Formulating prescription opioids to limit abuse remains a priority. OROS® extended-release (ER) hydromorphone HCl (EXALGO®) may have low abuse potential. Three post-marketing studies of the relative abuse liability of OROS hydromorphone ER were conducted. METHODS: Estimates of abuse, unadjusted and adjusted for prescription volume, were generated for OROS hydromorphone ER and comparators from Q2 2010 through Q2 2014 for a high-risk, substance abuse treatment population and the general population using poison control center data...
January 2, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29298185/a-multivariate-validity-analysis-of-the-pain-related-cognitive-processes-questionnaire
#10
Melissa A Day, L Charles Ward, Mark P Jensen
BACKGROUND: The Pain-Related Cognitive Processes Questionnaire (PCPQ) provides a multifaceted assessment of different styles of pain-related attentional processing. The present study examined the construct validity of the 4 PCPQ composite scales. METHODS: Exploratory structural equation modeling (ESEM) was applied to data from two college student samples (N=544) to derive reference variable factors which provided the context for drawing inferences regarding the construct validity of the PCPQ scales...
January 2, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29298184/cortical-pain-response-of-newborn-infants-to-venepuncture-a-randomised-controlled-trial-comparing-analgesic-effects-of-sucrose-versus-breastfeeding
#11
Stéphane Rioualen, Virginie Durier, David Hervé, Laurent Misery, Jacques Sizun, Jean Michel Roué
OBJECTIVE: Sucrose administration and breastfeeding decrease behavioural expressions of pain in neonates. However, recent studies indicated there is a persistent cortical response with sucrose. This study compared the efficacy of sucrose administration versus breastfeeding to decrease cortical responses to pain during venepuncture. METHODS: A randomised, prospective, controlled trial was conducted in a tertiary level maternity ward. Healthy 3-day-old term neonates, undergoing venepuncture for neonatal screening, were randomly assigned to receive sucrose solution or be breastfed before venepuncture...
January 2, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29271799/do-we-measure-what-patients-feel-an-analysis-of-correspondence-between-somatosensory-modalities-upon-quantitative-sensory-testing-and-self-reported-pain-experience
#12
Janne Gierthmühlen, Andreas Binder, Matti Förster, Ralf Baron
OBJECTIVES: Hyperalgesia and allodynia are typical signs of neuropathic pain. Quantitative sensory testing (QST) is a validated tool to clinically assess these phenomena. However, whether QST reveals findings that are reported by the patients is unclear. The aim of this study was therefore to investigate the association between self-reported symptoms assessed with the painDETECT® questionnaire (PDQ) with results of validated QST. METHODS: PDQ and QST data of 96 patients with chronic neuropathic pain were analysed...
December 21, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29271798/does-self-compassion-benefit-couples-coping-with-vulvodynia-associations-with-psychological-sexual-and-relationship-adjustment
#13
Marie Santerre-Baillargeon, Natalie O Rosen, Marc Steben, Pâquet Myriam, Rocio Macabena Perez, Sophie Bergeron
OBJECTIVES: Vulvodynia, a chronic vulvovaginal pain condition, has deleterious consequences for the psychological, relational, and sexual well-being of affected women and their partners. Protective factors, which can reduce these negative effects, are increasingly studied in the field of chronic pain. One of these, self-compassion, entails qualities such as kindness toward oneself, and has been associated with better adjustment in individuals with chronic pain. Because many women with vulvodynia have a negative image of themselves in the context of sexuality, self-compassion may be especially relevant for this population...
December 21, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29271797/brain-metabolite-changes-in-the-anterior-cingulate-cortex-of-chronic-low-back-pain-patients-and-correlations-between-metabolites-and-psychological-state
#14
Takuya Kameda, Sei Fukui, Ryoji Tominaga, Miho Sekiguchi, Narihito Iwashita, Kazuki Ito, Sachiko Tanaka-Mizuno, Shin-Ichi Konno
OBJECTIVES: In chronic low back pain (CLBP) patients, study of altered brain metabolites in the anterior cingulate cortex (ACC) using magnetic resonance spectroscopy (MRS) could reveal the detailed pathology of CLBP and depression. The aim was to detect the central difference between CLBP and controls by means of measuring the metabolites in the ACC, and to analyze the correlations between depression and metabolites in ACC. METHODS: MRS was performed in CLBP patients (n=60) and control subjects (n=56) to evaluate the effects of CLBP on metabolites in the ACC and to analyze the correlations between metabolites and questionnaire scores in a cross-sectional study...
December 21, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29271796/mindfulness-and-chronic-headache-migraine-mechanisms-explored-through-the-fear-avoidance-model-of-chronic-pain
#15
Biyanka Komandur, Paul R Martin, Siavash Bandarian-Balooch
OBJECTIVES: (1) To replicate a study by Schutze, Rees, Preece, and Schutze (2010) on a headache sample, rather than a heterogeneous chronic pain sample, investigating whether level of mindfulness predicts key components in the fear-avoidance model of chronic pain (pain intensity, negative affect, pain catastrophizing, pain-related fear, pain hypervigilance, and functional disability); (2) to investigate the relationships between level of mindfulness and headache/migraine pain intensity, frequency, and duration...
December 21, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29252869/altered-spontaneous-brain-activity-in-patients-with-idiopathic-trigeminal-neuralgia-a-resting-state-functional-mri-study
#16
Jie Yuan, Song Cao, Yue Huang, Yi Zhang, Peng Xie, Yu Zhang, Bao Fu, Tijiang Zhang, Ganjun Song, Tian Yu, Mazhong Zhang
OBJECTIVES: To identify the changes of local coherence and intrinsic brain activity in resting-state idiopathic trigeminal neuralgia (ITN) patients by using regional homogeneity (ReHo) and fractional aptitude of low-frequency fluctuation (fALFF) analysis. Correlations between spontaneous pain intensity and ReHo or fALFF were analyzed. METHODS: ReHo and fALFF were analyzed in 23 ITN patients and 23 age- and gender- matched healthy controls to detect the functional abnormality in the brains of ITN patients...
December 15, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29252868/efficacy-and-safety-outcome-domains-and-outcome-measures-in-systematic-reviews-of-neuropathic-pain-conditions
#17
Svjetlana Dosenovic, Antonia Jelicic Kadic, Milka Jeric, Matija Boric, Domagoj Markovic, Katarina Vucic, Livia Puljak
OBJECTIVES: Heterogeneity of outcome domains, used in interventional trials and systematic reviews (SRs) for neuropathic pain (NeuP), makes decisions on the comparative effectiveness of available treatments difficult. This study analyzed outcome domains and measures used in SRs of randomized controlled trials on efficacy and safety of interventions for NeuP and compared them with the core outcome set (COS) and core outcome measures (COMs) for chronic pain recommended by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT)...
December 15, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29200017/efficacy-of-eight-different-drug-treatments-for-patients-with-trigeminal-neuralgia-a-network-meta-analysis
#18
Fang Yang, Qiang Lin, Lihua Dong, Xiaohui Gao, Su'e Zhang
OBJECTIVES: Frequent trigeminal neuralgia (TN) is commonly seen in older persons and negatively influences a patient's daily life. Although some research on the efficacy of TN drugs has been conducted in the past, the optimal choice still remains uncertain. Therefore, this network meta-analysis evaluates the efficacy and performance of eight drugs with respect to TN. METHODS: All literature was retrieved from the PubMed and Embase electronic databases by jointly searching key terms...
December 1, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29200016/intravenous-acetaminophen-reduces-length-of-stay-via-mediation-of-postoperative-opioid-consumption-following-posterior-spinal-fusion-in-a-pediatric-cohort
#19
Vanessa A Olbrecht, Lili Ding, Kristie Spruance, Monir Hossain, Senthilkumar Sadhasivam, Vidya Chidambaran
OBJECTIVES: Since approval of IV acetaminophen (IV APAP), its use has become quite common without strong positive evidence. Our goal was to determine the effect of IV APAP on hospital length of stay (LOS) via mediation of opioid-related side effects in pediatric patients. METHODS: Following IRB approval, 114 adolescents undergoing posterior spinal fusion were prospectively recruited and managed postoperatively with patient controlled analgesia and adjuvant therapy...
December 1, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29210805/development-of-a-simple-preoperative-risk-score-for-persistent-pain-after-breast-cancer-surgery-a-prospective-observational-cohort-study
#20
Domitille Dereu, Georges L Savoldelli, Christophe Combescure, Stanislas Mathivon, Benno Rehberg
OBJECTIVES: Persistent postoperative pain concerns 30 to 50% of patients following breast cancer surgery. Studies testing preventive measures, however, have so far failed to produce consistent positive results. If preventive measures could be targeted to a subgroup of patients at high risk of persistent pain, positive results would be more likely. Our aim was to develop a simple risk score predicting persistent pain after breast cancer surgery. METHODS: In a prospective observational cohort study, we tested the predictive ability of a 4 simple items score for persistent pain in 200 patients scheduled for breast cancer surgery...
November 28, 2017: Clinical Journal of Pain
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