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Clinical Journal of Pain

Lisa V Doan, Jing Wang
OBJECTIVE: In the context of the current opioid epidemic, there has been a renewed interest in the use of ketamine as an analgesic agent. METHODS: We have reviewed ketamine analgesia. RESULTS: Ketamine is well-known as an antagonist for N-methyl-D-aspartate receptors. In addition, it can regulate the function of opioid receptors and sodium channels. Ketamine also increases signaling through α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors...
June 20, 2018: Clinical Journal of Pain
Peilong Dong, Xiaobo Tang, Rongrong Cheng, Jian Wang
BACKGROUND AND AIM: The severe pain after total knee arthroplasty (TKA) brings many patients more suffering, longer hospital stay and higher expenses. This study was designed to assess the relative efficacy of several clinical treatments for postoperative analgesia of TKA through network meta-analysis (NMA) based on multiple published randomized controlled trials. METHODS: Embase and PubMed were utilized to conduct this network meta-analysis from inception until 2016...
June 2, 2018: Clinical Journal of Pain
James Dunning, Raymond Butts, Ian Young, Firas Mourad, Victoria Galante, Paul Bliton, Michelle Tanner, César Fernández-de-Las-Peñas
OBJECTIVES: To compare the effects of adding electrical dry needling into a manual therapy and exercise program on pain, stiffness, function, and disability in individuals with painful knee osteoarthritis (OA). METHODS: Two hundred and forty-two participants (n=242) with painful knee OA were randomized to receive 6 weeks of electrical dry needling, manual therapy and exercise (n=121) or manual therapy and exercise (n=121). The primary outcome was related-disability as assessed by the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index at 3 months...
May 28, 2018: Clinical Journal of Pain
Keren Grinberg, Michal Granot, Lior Lowenstein, Liora Abramov, Irit Weissman-Fogel
OBJECTIVES: A patient's personal interpretations of a health threat or "illness perceptions" (IPs) are associated with their clinical outcomes. This study explored whether IPs are associated with pain severity and ability to modulate pain in women with chronic pelvic pain syndrome (CPPS), as well as the predictive value of IPs on Myofascial Physical Therapy (MPT) success. METHODS: Illness Perceptions Questionnaire - Revised (IPQ-R), mechanical and heat pain thresholds, mechanical temporal summation (mTS), and conditioned pain modulation (CPM) were evaluated in CPPS patients (n=39) before, and 3 months after MPT...
May 25, 2018: Clinical Journal of Pain
Eugene Kim, Sean Gamble, Adina Schwartz, Giovanni Cucchiaro
OBJECTIVES: Neuromodulation, particularly intrathecal drug delivery systems and spinal cord stimulators, can be a valuable tool when treating chronic pain in adults. However, there is a paucity of literature regarding its use in pediatrics. MATERIALS: and Methods: We present a series of 14 children and adolescents with intractable pain who received a spinal cord stimulator or a pump for the intrathecal delivery of medications between 2010 and 2016 at our institution...
May 22, 2018: Clinical Journal of Pain
Xiuqin Wang, Naifu Liu, Jinlong Chen, Zan Xu, Fumei Wang, Chuan Ding
BACKGROUND: Dexmedetomidine has been shown to have an analgesic effect. However, no consensus was reached in previous studies. METHODS: Electronic databases such as PubMed, Embase, and Cochrane Central were searched for relevant randomized controlled trials (RCTs). The relative risk (RR) and weighted mean difference (WMD) were used to analyze the outcomes. Random-effects model was used for meta-analysis. RESULTS: Compared to the normal saline group, patients using dexmedetomidine showed a significantly decreased pain intensity within 6 hours (WMD=-0...
May 16, 2018: Clinical Journal of Pain
Mohamed Y Makharita, Hanaa M El Bendary, Zainab M Sonbul, Salma El Sayed Ahmed, Mahmoud Abdel Latif
OBJECTIVES: This study was designed to evaluate the efficacy and safety of ultrasound-guided pulsed radiofrequency (PRF) for the intercostal nerves (ICNs) in the management of thoracic post-herpetic neuralgia (PHN). METHODS: After 2 weeks of treatment by pregabalin 150▒mg/12 hours, patients were randomly allocated into 2 groups. The PRF group, after ultrasound-guided localization of the ICN of the affected thoracic dermatome, sensory stimulation of the ICN was tested...
May 11, 2018: Clinical Journal of Pain
Anna Newell, Jennifer Keane, Brian E McGuire, Caroline Heary, Vincent McDarby, Bernie Dudley, Josh Moran, Kady Francis, Line Caes
OBJECTIVES: The aim of the current research was to compare the relative efficacy of interactive and passive distraction, with or without parental psychoeducation, on child pain and distress during a venepuncture. We also compared the effect of parental psychoeducation on parental distress, knowledge of distraction strategies and engagement in distraction. METHODS: This cross-sectional study included 213 children scheduled for a venepuncture, and one of their parents, who were randomly allocated to one of four conditions; interactive distraction, passive distraction, interactive distraction with parent psychoeducation and passive distraction with parent psychoeducation...
May 10, 2018: Clinical Journal of Pain
Lisbeth Frostholm, Christina Hornemann, Eva Ørnbøl, Per Fink, Mimi Mehlsen
OBJECTIVES: The aims of our study were (1) To identify possible subgroups of chronic pain sufferers based on their illness perceptions (IPs); (2) To examine whether these subgroups differed in health status and health expenditure, and (3) To examine whether the subgroups differed in their response to participation in a lay-led Chronic Pain Self-Management Program (CPSMP). METHODS: Four hundred and twenty-four participants in a randomized controlled trial on the CPSMP completed a questionnaire on their perceptions of their chronic pain condition at baseline...
May 10, 2018: Clinical Journal of Pain
Liyang Song, Pencheng Qiu, Jiaqi Xu, Jiawen Lv, Shengyu Wang, Chen Xia, Pengfei Chen, Shunwu Fan, Xiangqian Fang, Xianfeng Lin
OBJECTIVE: To evaluate the difference between combination pharmacotherapy and monotherapy on low back pain. METHODS: We searched PubMed, Embase, and Cochrane Central Register of Controlled Trials databases up to March 14, 2017. Two authors independently extracted the data and assessed the validity of included trials. RESULTS: Twelve randomized controlled trials comparing the effect of low back pain combination pharmacotherapy to monotherapy or placebo were included...
May 5, 2018: Clinical Journal of Pain
Helle Nygård Kristensen, Søren Lundbye-Christensen, Helle Haslund-Thomsen, Thomas Graven-Nielsen, Erik Elgaard Sørensen
INTRODUCTION: Hospitalized children often describe needle-related procedures as the worst pain possible and such procedures may be emotionally traumatic. The use of hospital clowns related to painful medical procedures in children may offer pain relief, but this has not been systematically evaluated. The objective of this study was to assess the effect of a therapeutic clown in comparison to standard care on the experience of pain for children receiving venipuncture. METHODS: A sample of 116 children aged 4-15 years consecutively admitted to the hospital was allocated to either the experimental (presence of hospital clown) or control group (standard care) prior to venipuncture...
May 5, 2018: Clinical Journal of Pain
Teresa A Lillis, John Burns, Frances Aranda, Yanina A Purim-Shem-Tov, Stephen Bruehl, Jean C Beckham, Stevan E Hobfoll
BACKGROUND: Given high levels of traumatic stress for low-income, inner-city women, investigating the link between PTSD and pain is especially important. PURPOSE: Using the Conservation of Resources (COR) Theory, we investigated direct and indirect relationships of PTSD symptoms, vulnerability factors (i.e., resource loss, depressive symptoms and social undermining), and resilience factors (i.e., optimism, engagement, and social support) to acute pain reports in a sample of low-income, inner-city women...
May 4, 2018: Clinical Journal of Pain
Hui Liu, Fan Lu, Dan Zhou, Yan Yin, Jun Li, BangXiang Yang, Li Song, Ling Ye, Hong Xiao
OBJECTIVES: This study evaluates the analgesic efficacy and emotional response of intravenous lidocaine infusion compared with placebo in patients with postherpetic neuralgia(PHN). METHODS: In this randomized, double-blinded study, patients with PHN received 5▒mg/kg intravenous lidocaine infusion or placebo. The primary outcome was pain relief measured by Visual Analogue Scale (VAS), Von Frey and area of allodynia. Moreover, emotional status of anxiety and depression were evaluated by Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS)...
April 25, 2018: Clinical Journal of Pain
Jillian Vinall, Melanie Noel, Timothy Disher, Kim Caddell, Marsha Campbell-Yeo
OBJECTIVES: The birth of a preterm infant and witnessing ones' infant in pain is remembered by parents as being one of the most stressful aspects of the neonatal care intensive unit (NICU). Elevated symptoms of posttraumatic stress symptoms (PTSS) are highly prevalent among mothers of preterm infants, however, little is known about mothers' memories of invasive procedures in the NICU and how these memories may contribute to the development of PTSS. We examined the relationships between number of invasive procedures, mothers' memories of these procedures, and their PTSS at discharge from the NICU...
April 25, 2018: Clinical Journal of Pain
Xianwei Che, Robin Cash, Sin Ki Ng, Paul Fitzgerald, Bernadette M Fitzgibbon
OBJECTIVE: This review aimed to explore the processes that underlie the main and the buffering effect of social support on decreased pain experience. METHODS: The systematic review was conducted according to the PRISMA guidelines. Online databases of PubMed and PsycINFO were searched for peer-reviewed articles using keywords (("social support", OR "interpersonal", OR "social presence", OR "spouse", OR "couple", OR "marriage") AND "pain")...
April 24, 2018: Clinical Journal of Pain
Kevin E Vowles, Robert W Bailey, Mindy L McEntee, Melissa Pielech, Karlyn A Edwards, Lena A Bolling, W Evan Rivers
OBJECTIVES: It is important to identify aspects of analgesic use that are associated with harm in chronic pain. Historically, the focus has been patterns of use (e.g., overuse). This study evaluated another aspect of use - rather than evaluating how analgesics were being used, the primary interest was in why they were being used. METHODS: 334 analgesic using individuals with chronic pain responded to a pool of items assessing reasons for analgesic use. Measures of pain intensity, distress, depression, and opioid and alcohol misuse were also completed...
April 24, 2018: Clinical Journal of Pain
Carlos Suso-Ribera, Diana Castilla, Irene Zaragozá, María Victoria Ribera-Canudas, Cristina Botella, Azucena García-Palacios
OBJECTIVES: Ecological momentary assessment is recommended in the management of chronic pain. Smartphone apps might be a useful tool for that purpose. This study goal was to develop and test a multidimensional smartphone app for adults with chronic pain. A multidisciplinary team developed app content after a series of meetings, considering clinical guidelines for pain measurement. Content included pain intensity and interference, fatigue, mood, perceived health status, activity level, side effects of the medication, use of rescue medication, and pain-related psychological constructs (catastrophizing, acceptance, fear, and coping)...
April 13, 2018: Clinical Journal of Pain
Stephen J Neville, Andrew Clauw, Stephanie E Moser, Andrew Urquhart, Daniel J Clauw, Chad M Brummett, Steven E Harte
OBJECTIVES: The present study evaluated the relationship between the 2011 American College of Rheumatology fibromyalgia (FM) survey criteria and quantitative sensory testing (QST). METHODS: Patients with knee osteoarthritis scheduled to undergo knee arthroplasty completed the FM survey criteria and self-report measures assessing clinical symptoms. Patients also underwent a battery of QST procedures at the surgical knee and remote body sites, including pressure algometry, conditioned pain modulation (CPM), and temporal summation (TS)...
April 10, 2018: Clinical Journal of Pain
Nabiha Benyamina Douma, Charles Côté, Anaïs Lacasse
OBJECTIVES: Low back pain (LBP) is frequent and burdensome among police officers, but occupational and ergonomic factors associated with LBP and its chronic symptoms have never been studied among these workers using a biopsychosocial model. This study aimed at exploring such factors associated with acute/subacute LBP and chronic low back pain (CLBP) among car-patrol police officers. METHODS: A web-based cross-sectional study was conducted among car-patrol officers working in the province of Quebec (Canada)...
April 10, 2018: Clinical Journal of Pain
Edin T Randall, Kelly R Smith, Caitlin Conroy, Allison M Smith, Navil Sethna, Deirdre E Logan
OBJECTIVES: To provide a descriptive account of long-term functioning (≥five years post-treatment) among youth who completed intensive interdisciplinary pain treatment (IIPT) for pediatric chronic pain conditions. METHODS: 95 patients (mean age at follow-up=20.0▒y) treated at least five years previously at a single IIPT program completed questionnaires assessing pain, functional disability, healthcare utilization, academic/career achievement and quality of life...
April 10, 2018: Clinical Journal of Pain
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