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Clinical Journal of Pain

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https://www.readbyqxmd.com/read/28731960/perceived-pain-extent-is-not-associated-with-widespread-pressure-pain-sensitivity-clinical-features-related-disability-anxiety-or-depression-in-women-with-episodic-migraine
#1
Cesar Fernández-de-Las-Peñas, Deborah Falla, María Palacios-Ceña, Stella Fuensalidad-Novo, Jose L Arias-Buría, Alessandro Schneebeli, Lars Arend-Nielsen, Marco Barbero
OBJECTIVE: People with migraine present with varying pain extent and an expanded distribution of perceived pain may reflect central sensitization. The relationship between pain extent and clinical features, psychological outcomes, related-disability and pressure pain sensitivity in migraine has been poorly investigated. Our aim was to investigate whether the perceived pain extent, assessed from pain drawings, relates to measures of pressure pain sensitivity, clinical, psychological outcomes, and related-disability in women with episodic migraine...
July 20, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28731959/efficacy-of-intra-articular-botulinum-toxin-in-osteo-articular-joint-pain-a-meta-analysis-of-randomized-controlled-trials
#2
Mathilde Courseau, Pascale Vergne Salle, Danièle Ranoux, Anais de Pouilly Lachatre
OBJECTIVE: To evaluate the efficacy of intra-articular injections of botulinum toxin A (BT-A) into the painful joint diseases through a systematic review of the literature and a meta-analysis of controlled randomized trials. Indeed, intra articular therapies (corticosteroids, hyaluronic acid) have limited efficacy and run a risk of toxicity in patients with joint pain. New therapeutic options are needed to treat painful osteo-articular disease. METHODS: We searched via Pubmed, ACR and EULAR congresses and grey literature for the studies reported until June 2016 and addressing the issue of BT intra articular injections in patients with refractory joint pain...
July 20, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28731958/pain-catastrophizing-and-pain-health-related-quality-of-life-in-endometriosis
#3
Allison E McPeak, Catherine Allaire, Christina Williams, Arianne Albert, Sarka Lisonkova, Paul J Yong
OBJECTIVES: To determine if pain catastrophizing is independently associated with pain health-related quality-of-life in women with endometriosis, independent of potential confounders. METHODS: Analysis of cross-sectional baseline data from a prospective database at a tertiary referral center for endometriosis/pelvic pain. Referrals to the center were recruited between December 2013 to April 2015, with data collected from online patient questionnaires, physical examination, and review of medical records...
July 20, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28731957/longitudinal-postoperative-course-of-pain-and-dysfunction-following-total-knee-arthroplasty
#4
Katherine Hadlandsmyth, M Bridget Zimmerman, Roohina Wajid, Kathleen A Sluka, Keela Herr, Charles R Clark, Nicolas O Noiseux, John J Callaghan, Barbara A Rakel
OBJECTIVES: While the majority of patients undergoing Total Knee Arthroplasty report substantial improvement in pain and function, a significant subset experience persistent post-surgical pain and dysfunction. Better understanding of the longitudinal postoperative course is needed, including the association between patient status following physical rehabilitation at 6 weeks post-TKA, to six month outcomes. This study aims to described the postoperative course of TKA and examine variables associated with change in pain and functioning between 6 weeks and 6 months post-TKA...
July 20, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28719509/the-relationship-between-structural-and-functional-brain-changes-and-altered-emotion-and-cognition-in-chronic-low-back-pain-a-systematic-review-of-mri-and-fmri-studies
#5
Sin Ki Ng, Donna M Urquhart, Paul B Fitzgerald, Flavia M Cicuttini, Sultana Monira Hussain, Bernadette M Fitzgibbon
OBJECTIVES: Chronic low back pain (CLBP) is a major health issue, yet its underlying mechanisms remain unknown. Studies have demonstrated the importance of emotion and cognition in chronic pain, however, the relevant brain physiology in magnetic resonance imaging (MRI) studies are unclear in CLBP populations. Therefore, this review aimed to identify MRI brain changes and examine their potential relationship with emotional and cognitive processes in CLBP. METHOD: A systematic search was conducted in 5 databases...
July 17, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28719508/is-the-organisation-of-the-primary-motor-cortex-in-low-back-pain-related-to-pain-movement-and-or-sensation
#6
Edith Elgueta-Cancino, Siobhan Schabrun, Paul Hodges
Primary motor cortex (M1) organisation differs between individuals with and without chronic low back pain (CLBP), in parallel with motor and sensory impairments. This study investigated whether movement behaviour and tactile/pain sensation are related to M1 organisation in CLBP. Transcranial magnetic stimulation (TMS) was used to map the M1 representation of the erector spinae and multifidus muscles in 20 participants with and without CLBP. Cortical organisation was quantified by: map volume; center of gravity (CoG); number of peaks; and primary and secondary peak location...
July 17, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28719507/the-relationship-between-chronic-pain-and-neurocognitive-function-a-systematic-review
#7
Diana M Higgins, Aaron M Martin, Dewleen G Baker, Jennifer J Vasterling, Victoria Risbrough
OBJECTIVE: Understanding the relationship between chronic pain and neurocognition has important implications for the assessment and treatment of pain. This paper provides an overview of the current literature examining the neurocognition-chronic pain relationship and suggests future avenues of research, along with a discussion of clinical implications of the literature findings. Consideration of potential moderators and mediators of this relationship, as well as a brief discussion of the importance of future research in special populations at particular risk for these problems, are also a focus of this paper...
July 17, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28678061/pain-in-children-with-cancer-prevalence-characteristics-and-parent-management
#8
Perri R Tutelman, Christine T Chambers, Jennifer N Stinson, Jennifer A Parker, Conrad V Fernandez, Holly O Witteman, Paul C Nathan, Melanie Barwick, Fiona Campbell, Lindsay A Jibb, Karen Irwin
OBJECTIVES: Pain is a common and distressing symptom of pediatric cancer, as reported by both children and their parents. Increasingly, children with cancer are cared for as outpatients, yet little is known about how parents manage their cancer-related pain. The aim of the current study was to examine pain prevalence and characteristics, and the pharmacological, physical and psychological pain management strategies used by parents to manage their child's cancer pain. METHODS: In total, 230 parents and caregivers (89% mothers) of children (mean age=8...
July 3, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28678060/association-between-clinical-and-neurophysiological-outcomes-in-patients-with-mechanical-neck-pain-and-whiplash-associated-disorders
#9
Matteo Castaldo, Antonella Catena, Alessandro Chiarotto, Jorge Hugo Villafañe, César Fernández-de-Las-Peñas, Lars Arendt-Nielsen
OBJECTIVES: To investigate the association between pain, disability, trigger points (TrPs) and pressure pain thresholds (PPTs) in patients with mechanical (MNP) or whiplash-associated disorders (WAD). METHODS: Forty-six MNP and fifty-one WAD patients underwent a physical examination consisting of cervical range of motion, PPTs in the upper trapezius and tibialis anterior muscles, TrPs examination in the upper trapezius, and collection of clinical data including disability, pain intensity and spontaneous symptomatic pain area...
July 3, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28678059/peripheral-interventions-for-painful-stump-neuromas-of-the-lower-limb-a-systematic-review
#10
Stephanie Alexandra Poyntz, Milind Dalal, Nicholas Hacking, Stephen Fowler
OBJECTIVES: Painful stump neuromas in lower limb amputees are a significant burden on a person's quality of life due to interference with wearing prostheses and therefore the ability to walk. Treating painful stump neuromas is a challenge perhaps reflected by the lack of clinical guidelines both in the United Kingdom and internationally. METHODS: A systematic review was conducted to evaluate the efficacy of all treatments tried in the management of symptomatic neuromas in the lower limb amputation stump in order to establish whether one treatment is superior...
July 3, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28654559/the-role-of-preoperative-radiological-severity-sensory-testing-and-temporal-summation-on-chronic-postoperative-pain-following-total-knee-arthroplasty
#11
Kristian Kjær Petersen, Ole Simonsen, Mogens Berg Laursen, Lars Arendt-Nielsen
OBJECTIVES: Knee osteoarthritis (KOA) can be associated with local and central sensitization. As an indicator of the central gain, facilitated temporal summation of pain (TSP) has been found in KOA patients. This facilitation is predictive of the development of chronic postoperative pain after total knee arthroplasty (TKA). Other studies have suggested hypoesthesia/hypoalgesia to thermal stimuli as a feature in KOA. This study investigated associations between preoperative TSP, thermal sensitivity and radiological severity for the development of chronic postoperative pain after TKA...
June 16, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28654558/the-efficacy-of-ultrasound-guided-type-ii-pectoral-nerve-blocks-in-perioperative-pain-management-for-immediate-reconstruction-after-modified-radical-mastectomy-a-prospective-randomized-study
#12
Kaiyuan Wang, Xiaobei Zhang, Tingting Zhang, Hui Yue, Shan Sun, Hongwei Zhao, Peng Zhou
OBJECTIVES: The pectoral nerves (Pecs) II block is a technique that places local anesthetic between the thoracic muscles to block the axillary and breast regions. This study aimed to compare the quality of perioperative analgesia and side effects of the Pecs II block under general anesthesia versus general anesthesia alone in immediate unilateral breast reconstruction with an implant and latissimus dorsi (LD) flap after modified radical mastectomy. METHODS: Sixty-four patients scheduled for immediate breast reconstruction after modified radical mastectomy were randomly allocated into the Pecs II block under general anesthesia group (Group P, n=32) or the general anesthesia alone group (Group G, n=32)...
June 16, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28654557/the-effectiveness-of-transcranial-direct-current-stimulation-as-an-add-on-modality-to-graded-motor-imagery-for-treatment-of-complex-regional-pain-syndrome-a-randomized-proof-of-concept-study
#13
Émilie Lagueux, Michaël Bernier, Patricia Bourgault, Kevin Whittingstall, Catherine Mercier, Guillaume Léonard, Sarah Laroche, Yannick Tousignant-Laflamme
BACKGROUND: The efficacy of graded motor imagery (GMI) for the management of complex regional pain syndrome (CRPS) is supported by evidence, but its treatment effect remains generally modest. Transcranial direct current stimulation (tDCS) has been advocated as an adjunct intervention to enhance the effect of motor imagery approaches in pain populations. OBJECTIVE: The purpose of this study was to investigate the effectiveness of GMI+active tDCS compared to the GMI+sham tDCS in the treatment of CRPS type I...
June 16, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28654556/patient-controlled-intravenous-analgesia-with-combination-of-dexmedetomidine-and-sufentanil-on-patients-after-abdominal-operation-a-prospective-randomized-controlled-blinded-multicenter-clinical-study
#14
Yongtao Gao, Xiaoming Deng, Hongbing Yuan, Yufang Leng, Tiezheng Zhang, Xuzhong Xu, Suming Tian, Jun Fang, Wen Ouyang, Xinming Wu
OBJECTIVE: To investigate the effect of combination of dexmedetomidine and sufentanil on patient-controlled intravenous analgesia (PCIA) in patients after abdominal operation and to assess the safety and validity of this treatment. METHODS: This is a prospective, randomized controlled, blinded, multicenter clinical study. A total of 210 patients from 9 clinical research centers underwent selective abdominal operation with general anesthesia were enrolled in the study, including laparoscopic-assisted abdominal operation on stomach, intestines or open surgery on stomach, intestines, kidneys and liver, ASA status I-II...
June 16, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28654555/the-experience-of-pain-dismissal-in-adolescence
#15
Ellen K Defenderfer, Kate Bauer, Eva Igler, Julia A Uihlein, W Hobart Davies
CONTEXT: Pain in adolescence has psychosocial effects lasting into adulthood, including increased likelihood of pain in adulthood and higher rates of depression and anxiety. Many adolescents with chronic pain describe skepticism of pain reports, but this has not yet been evaluated in a sample of typically developing adolescents. OBJECTIVE: The current study sought to describe the experience of perceived pain dismissal during adolescence in a community sample. METHOD: Nearly two-thousand (1931) emerging adults were recruited from the community and answered open-ended questions regarding whether they had experienced dismissal of their pain in adolescence, who dismissed their pain, characteristics of the dismisser, and what that experience was like...
June 16, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28617716/hybrid-blocks-for-total-knee-arthroplasty-a-technical-description
#16
David F Johnston, Rakesh V Sondekoppam, Vishal Uppal, James L Howard, Sugantha Ganapathy
This narrative review article aims to examine current evidence of knee innervation in order to develop a technique of targeting pure sensory innervation of the knee joint without compromising motor function. A literature review of knee innervation was performed to gain an anatomic understanding of terminal sensory branches of the relevant target nerves (femoral, obturator, sciatic, and lateral femoral cutaneous). Pure sensory block of the knee joint is challenging due to important contributions from the muscular innervation close to the joint and the variability of nerves afferents contained within and around the adductor canal...
June 14, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28609308/evaluation-of-a-clinical-protocol-to-assess-and-diagnose-neuropathic-pain-during-acute-hospital-admission-results-from-traumatic-spinal-cord-injury
#17
Lise M A Bélanger, Hamed S Umedaly, Vanessa K Noonan, So Eyun Park, Jennifer Prince, Nancy P Thorogood, Tian Shen, Andrea F Townson, John T Street, Marcel F Dvorak, Michael Negraeff
OBJECTIVES: A clinical protocol was developed for clinicians to routinely assess and initiate treatment for patients with neuropathic pain (NP) in an acute care setting. The objectives of this study were to: (1) determine the incidence and onset of NP in patients with traumatic SCI during acute care and (2) describe how the implementation of a clinical protocol impacts the assessment and diagnosis of NP. METHODS: The study was a cohort analysis with a pre-post-test utilizing a historical control...
June 12, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28591086/dexamethasone-injected-perineurally-is-more-effective-than-administered-intravenously-for-peripheral-nerve-blocks-a-meta-analysis-of-randomized-controlled-trials
#18
Andres Zorrilla-Vaca, Jinlei Li
INTRODUCTION: Peripheral nerve blocks (PNBs) are widely and increasingly used for better acute perioperative pain control for a variety of procedures. Clinically preservative-free dexamethasone is arguably the most commonly used adjuvant and offers the most optimization effects on PNBs yet with the least side-effects noted. Our aim was to compare the effectiveness of intravenous versus perineural dexamethasone on the effectiveness and safety of PNBs. METHODS: Major databases (PubMed, EMBASE, Cochrane library, ISI Web of Science, Google Scholar) were systematically searched for randomized controlled trials (RCTs) comparing the effectiveness of intravenous versus perineural dexamethasone on peripheral nerve blocks...
June 6, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28591085/influence-of-oprm1-polymorphism-on-post-operative-pain-after-intrathecal-morphine-administration-in-italian-patients-undergoing-elective-cesarean-section
#19
Eleonora Pettini, Massimo Micaglio, Ubaldo Bitossi, Angelo Raffaele De Gaudio, Duccio Rossi Degl'Innocenti, Lorenzo Tofani, Vittorio Limatola, Chiara Adembri, Alessandro Di Filippo
OBJECTIVES: the aim of this prospective observational study was to evaluate the influence of OPRM1 polymorphism on the analgesic efficacy (including VAS scores and requirement for rescue analgesia) of a standard dose of intrathecal morphine METHODS:: an Italian cohort of 63 parturients, scheduled for elective cesarean section at a tertiary University Hospital, received a spinal anesthesia with hyperbaric bupivacaine and morphine 100 mcg. For the first 48 hours in the post-operative period the patients received acetaminophen 1 g IV q6hr...
June 6, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28591084/efficacy-of-postoperative-analgesia-of-local-ketamine-wound-instillation-following-total-thyroidectomy-a-randomized-double-blind-controlled-clinical-trial
#20
Ahmad M Abd El-Rahman, Fatma A El Sherif
BACKGROUND: Total thyroidectomy is recommended as a line of management of thyroid cancer in a lot of cases. Our aim was to compare postoperative analgesic effect of local ketamine 1 mg/kg instilled in the wound to I.M ketamine and to placebo after total thyroidectomy. METHODS: Ninety patients aged 18 - 60 years, American Society of Anesthesiologists (ASA) class I-II, with a body weight of 50-90 kg, scheduled for total thyroidectomy were enrolled after ethics committee approval in this prospective, randomized, double-blind, controlled study and divided randomly into three groups to receive after hemostasis: Group (I): 1 mg/kg ketamine in a total volume of 10 mL normal saline instilled in the wound...
June 6, 2017: Clinical Journal of Pain
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