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Clinical Journal of Pain

Cienwen J Town, James Johnson, André Van Zundert, Haakan Strand
OBJECTIVES: The review article was designed to assess the effectiveness of regional anesthesia, specifically peripheral nerve blocks, in the treatment of burn pain; with noting of clinical indications and contraindications for peripheral nerve block application, along with discussion of evidence-based analgesic strategies for providing improved, comprehensive burn pain management. METHODS: A search of relevant literature was performed using CINAHL, PubMed, EMBASE, Web of Science and SCOPUS with a publication date between January 2005 and December 2017...
December 11, 2018: Clinical Journal of Pain
Monica McCowat, Leanne Fleming, Julie Vibholm, Diane Dixon
OBJECTIVES: Numerous psychological factors have been found to be associated with acute and chronic pain following breast cancer surgery. However, individual studies tend to be limited to a small number of predictors and many fail to employ prospective designs. This study aimed to identify a broader range of psychological predictors of acute and chronic pain following breast cancer surgery through a systematic review of relevant prospective studies. METHODS: Web of Science, psychINFO, PubMed, and MEDLINE databases were searched to identify relevant prospective cohort studies...
November 30, 2018: Clinical Journal of Pain
Ahmed Salah Ahmed, Aktham Adel Shoukry, Mahmoud Ahmed Mohammed Kamel, Ashraf Mohammed Yehia Heikal, Naglaa Abdulla Ahmed
OBJECTIVES: To investigate the effects of the preoperative combination of oral pregabalin and intravenous magnesium sulphate as analgesic adjuvants in post thoracotomy pain. METHODS: One hundred and twenty patients with ASA physical status II were allocated randomly into one of four groups. Group MP received 300▒mg pregabalin orally and an intravenous (IV) infusion of magnesium sulphate 50▒mg/kg mixed with 200▒mL normal saline (NS); Group P received 300▒mg pregabalin orally and 200▒mL NS infusion; Group M received an IV infusion of magnesium sulphate 50▒mg/kg mixed with 200▒mL NS and a placebo capsule; and Group C received placebo capsule and an IV infusion of 200▒mL NS...
November 28, 2018: Clinical Journal of Pain
Xiaobing Yu, Tao Liu, Dewei Zhao, Ke Yang, Xiuzhi Zhang, Meng Zhang, Shuo Zhang, Wei Huang, Baolin Wu, Junlei Li
OBJECTIVE: Pregabalin has been approved for the treatment of the neuropathic pain following spinal cord injury (SCI). We performed a systemic review and meta-analysis of randomized, controlled, multicenter trials to evaluate the efficacy and safety of pregabalin for SCI-induced neuropathic pain. METHODS: Research searching was performed in PubMed and EMBASE databases and the Cochrane library at May 2018. Clinical controlled trials using pregabalin for the pain treatment following SCI in adults (≥18▒y old) were included...
November 28, 2018: Clinical Journal of Pain
Adina C Rusu, Hannah Gajsar, Michael-Christian Schlüter, Yara-Inken Bremer
OBJECTIVES: Information processing biases such as attentional biases, interpretation biases and memory biases are supposed to play a role in the exacerbation and maintenance of chronic pain. Current research in the area of cognitive biases shows that all these biases seem to have an influence on attention to, interpretation of and recall of pain and can lead to maladaptive strategies and the exacerbation of pain. METHODS: We conducted a narrative literature review, considering evidence extracted from various databases including PubMed, MEDLINE, Science Direct and ProQuest...
November 28, 2018: Clinical Journal of Pain
Qianchuang Sun, Shuyan Liu, Huiying Wu, He Ma, Wei Liu, Meidan Fang, Kexiang Liu, Zhenxiang Pan
OBJECTIVES: The objective of this meta-analysis was to evaluate the analgesic effects of dexmedetomidine (DEX) in transversus abdominis plane (TAP) blocks for abdominal surgery. METHODS: Electronic databases, including PubMed, EMBASE, Chinese National Knowledge Infrastructure (CNKI), Wan Fang, and the Cochrane Library , were conducted to collect the randomized controlled trials (RCTs) from inception to March 2018. RCTs investigating the impact of adding DEX to local anesthetics for TAP blocks were included in this analysis...
November 20, 2018: Clinical Journal of Pain
Timothy H Wideman, Robert R Edwards, David M Walton, Marc O Martel, Anne Hudon, David A Seminowicz
OBJECTIVES: Pain assessment is enigmatic. While clinicians and researchers must rely upon observations to evaluate pain, the personal experience of pain is fundamentally unobservable. This raises the question of how the inherent subjectivity of pain can and should be integrated within assessment. Current models fail to tackle key facets of this problem, such as what essential aspects of pain are overlooked when we only rely on numeric forms of assessment, and what types of assessment need to be prioritized to ensure alignment with our conceptualization of pain as a subjective experience...
November 15, 2018: Clinical Journal of Pain
Elena Tseli, Britt-Marie Stålnacke, Katja Boersma, Paul Enthoven, Björn Gerdle, Björn Olov Äng, Wilhelmus Johannes Andreas Grooten
OBJECTIVES: This systematic review aimed to identify and evaluate prognostic factors for long-term (≥6▒mo) physical functioning in patients with chronic musculoskeletal pain following multidisciplinary rehabilitation (MDR). METHODS: Electronic searches conducted in MEDLINE, PsycINFO, EMBASE, CINAHL, Web of Science, and Cochrane CENTRAL revealed 25 original research reports, published 1983-2016, (n=9436). Potential prognostic factors relating to initial pain and physical and psychological functioning were synthesized qualitatively and quantitatively in random effects meta-analyses...
October 26, 2018: Clinical Journal of Pain
Samantha Bunzli, Annick Maujean, Tonny Elmose Andersen, Michele Sterling
OBJECTIVES: Post-traumatic stress disorder (PTSD) symptoms are common among people with whiplash following a motor vehicle crash. The Impact of Events Scale - Revised (IES-R) screens for PTSD symptoms with psychologist referral recommended for above-threshold scores. Recent data indicate that PTSD symptoms post-whiplash may relate more to pain and disability than the crash itself. This study explored the interpretation of IES-R items by people with whiplash to establish whether responses relate to the crash or to whiplash pain and disability...
October 26, 2018: Clinical Journal of Pain
Michelle A Clementi, Pari Faraji, Katrina Poppert Cordts, Kelsey MacDougall, Anna Wilson, Tonya M Palermo, Amy Lewandowski Holley
OBJECTIVES: Biopsychosocial models emphasize the influence of parent/family factors on pediatric chronic pain. Little is known about how parent factors differ across the acute to chronic pain continuum, or contribute to youths' pain experience in the acute pain period. The purpose of the study was to describe parent factors in youth with acute musculoskeletal pain (n=84) compared to youth with chronic pain (n=60) and youth without pain (n=61). Further, within the acute pain sample, we tested parent factors as predictors of child pain characteristics, as well as the moderating role of child sex on associations...
October 22, 2018: Clinical Journal of Pain
Natoshia R Cunningham, Anjana Jagpal, Sarah Nelson, Kristen E Jastrowski Mano, Susan T Tran, Anne M Lynch-Jordan, Keri Hainsworth, James Peugh, Constance A Mara, Susmita Kashikar-Zuck
OBJECTIVE: Anxiety is common in pediatric chronic pain and is related to a higher risk for poor outcomes; thus, there is a need for effective clinical screening methods to identify youth with chronic pain and co-occurring anxiety. The Screen for Child Anxiety Related Disorders (SCARED) is a validated measure that defines clinically significant anxiety using the traditional clinical cut-off, but in pain populations, may fail to screen in youth with subclinical anxiety that may also be at increased risk...
October 22, 2018: Clinical Journal of Pain
Gamze Inan, Sevil Inal
OBJECTIVES: Invasive procedures are important causes of pain and anxiety during hospitalization. This study aims to evaluate the effect of three different distraction methods on the pain and anxiety levels of children during venipuncture. METHOD: This is a randomized controlled trial that was conducted with 180 children of 6-10 years of age; data was collected in the months of August - November 2016. Participants were randomized in 4 groups; the children in Group 1 watched cartoon movies (CM), the children in Group 2 played video games (VG), the children in Group 3 were distracted by their parents' verbal interactions (PI) whereas no distraction method was used on the children in Group 4 (control group (c)...
October 22, 2018: Clinical Journal of Pain
Dmitry Tumin, Rebecca Miller, Mohammed Hakim, Shabana Z Shafy, David Drees, Sharon Wrona, Timothy P Smith, Joseph D Tobias, Tarun Bhalla
OBJECTIVES: To retrospectively characterize the rate of referrals to an outpatient chronic pain clinic among adolescents with chronic pain, and to identify factors associated with referral. METHODS: Adolescents 13-18 years of age seen in 2010-2015 at outpatient clinics associated with Nationwide Children's Hospital (NCH) and diagnosed with chronic pain were included if they lived near NCH and had not been previously referred to the NCH outpatient chronic pain clinic...
October 9, 2018: Clinical Journal of Pain
Eugene R Viscusi
OBJECTIVES: Opioid analgesics may be associated with chronic adverse effects, such as opioid-induced constipation (OIC). Available and emerging prescription medications for OIC in patients with chronic noncancer pain are described, including concerns and challenges associated with OIC management. METHODS: Narrative review. RESULTS: Opioid-induced constipation is characterized by a change in bowel habits and defecation patterns that occurs when initiating opioid therapy and is associated with reduced bowel frequency, straining, sensation of incomplete evacuation, and/or patient distress related to bowel habits...
October 4, 2018: Clinical Journal of Pain
Cate Sinclair, Pamela Meredith, Jenny Strong, George A Chalkiadis
OBJECTIVES: Sensory modulation patterns contribute to altered pain perception and disengagement in activities; atypical sensory modulation patterns have been associated with higher pain sensitivity, catastrophizing, and reduced function. Objectives of this study were to ascertain whether: adolescents with persistent pain had atypical sensory modulation patterns, atypical sensory modulation was associated with reduced functioning and higher pain, and pain catastrophizing mediated the relationship between sensory modulation and functional disability...
October 3, 2018: Clinical Journal of Pain
Christine H Meyer-Frießem, Theresa Wiegand, Lynn Eitner, Christoph Maier, Tina Mainka, Jan Vollert, Elena K Enax-Krumova
OBJECTIVES: Spinal cord and peripheral nerve stimulation (SCS/PNS) alleviate chronic pain; however, the underlying mechanisms remain controversial. Aim of this observational study was to assess sensory changes in the ON- and OFF-conditions to obtain insights into mechanism of analgesic effects of SCS/PNS. METHODS: We contacted 85 patients and selected 28 patients with sufficient pain relief by SCS (n=15) or PNS (n=13) to assess their ongoing pain intensity (Numerical Rating Scale, NRS 0-10), pain thresholds using Quantitative Sensory Testing (DFNS-protocol) and conditioned pain modulation (CPM, conditioning stimulus: heat, test stimulus: cold water) in a non-randomized manner 2-4 hours after SCS/PNS deactivation (OFFcondition) and during stimulation (ON-condition)...
September 26, 2018: Clinical Journal of Pain
Brett Vaughan, Jane Mulcahy, Kylie Fitzgerald, Philip Austin
OBJECTIVE: Educating patients about the neurobiological basis of their pain experience is now an important part of managing patients with pain disorders. The aim of this study was to evaluate the measurement properties of the Neurophysiology of Pain Questionnaire (NPQ) in a population seeking osteopathy treatment for both acute and chronic musculoskeletal pain complaints. METHODS: Patients attending the Victoria University Osteopathy Clinic for their initial osteopathy consultation were recruited consecutively...
September 26, 2018: Clinical Journal of Pain
Tibor M Szikszay, Waclaw M Adamczyk, Kerstin Luedtke
OBJECTIVE: Offset analgesia (OA) is a test paradigm increasingly used to estimate endogenous pain modulation characterized by a disproportionally profound analgesia after a small decrease of a heat stimulus. This systematic review and meta-analysis examined the magnitude and difference of OA in healthy subjects and chronic pain patients. METHODS: Controlled trials, case-control studies, cross-sectional studies, case-series or other observational studies evaluating the effect of a ±1°C offset trial in healthy controls and patients with chronic pain were searched in PubMed, Web of Science, CINAHL, PEDro, PsycINFO and Cochrane CENTRAL...
September 21, 2018: Clinical Journal of Pain
Judith Kappesser, Elisa Kamper, Jan de Laffolie, Dirk Faas, Harald Ehrhardt, Linda S Franck, Christiane Hermann
OBJECTIVES: There are many neonatal pain assessment tools available nowadays. However, systematic psychometric comparisons between tools are still lacking, particularly those comparing tools regarding their ability to differentiate between pain and stressful procedures. The aim of the present study was to psychometrically compare five widely used neonatal pain assessment tools: Neonatal Facial Coding System-Revised (NFCS-R), Premature Infant Pain Profile-Revised (PIPP-R), Neonatal Pain, Agitation and Sedation Scale (N-PASS) Neonatal Infant Pain Scale (NIPS) and Bernese Pain Scale Neonates (BPSN)...
September 21, 2018: Clinical Journal of Pain
Christine Miaskowski, Steven M Paul, Judy Mastick, Gary Abrams, Kimberly Topp, Betty Smoot, Kord M Kober, Margaret Chesney, Mark Schumacher, Yvette P Conley, Marilyn Hammer, Steven Cheung, David Borsook, Jon D Levine
OBJECTIVES: Numbness associated with neuropathic pain suggests the loss of function in myelinated, large diameter sensory neurons. The purpose of this study was to examine the relationships between pain severity and subjective (ie, severity of numbness) and objective (ie, loss of light touch sensations, vibration thresholds) measures of loss of large fiber function in adult survivors with chemotherapy-induced peripheral neuropathy (CIPN, n=426) and breast cancer patients with persistent postsurgical pain (n=80)...
January 2019: Clinical Journal of Pain
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