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Clinical Gastroenterology and Hepatology

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https://www.readbyqxmd.com/read/29782998/measurement-of-salivary-pepsin-for-diagnosis-of-gerd-in-adults-and-children-is-not-yet-ready-for-clinical-application
#1
Philip Woodland, Maartje Mj Singendonk, Joanne Ooi, Kornilia Nikaki, Terry Wong, Chung Lee, Esteban Glasinovic, Romy Koning, Rene Lutter, Marc A Benninga, Michiel P van Wijk, Daniel Sifrim
No abstract text is available yet for this article.
May 18, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29778916/the-double-wall-sign
#2
Marco Ertreo, Alexander Somwaru
No abstract text is available yet for this article.
May 17, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29778915/tumor-seeding-associated-with-selected-gastrointestinal-endoscopic-interventions
#3
Ferga C Gleeson, Jeffrey H Lee, John M Dewitt
No abstract text is available yet for this article.
May 17, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29778914/recurring-hepatocellular-carcinomas-in-the-right-ventricle
#4
Jing Sun, Hongxia Qi, Yang Sun
No abstract text is available yet for this article.
May 17, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29778913/pneumatosis-cystoides-intestinalis
#5
Tsuyoshi Suda, Yukihiro Shirota, Tokio Wakabayashi
No abstract text is available yet for this article.
May 17, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29775796/growth-in-branch-duct-ipmn-undergoing-surveillance-unsafe-at-any-speed
#6
EDITORIAL
Koushik K Das, Daniel K Mullady
No abstract text is available yet for this article.
May 15, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29775795/response-to-biologics-delay-progression-of-crohn-s-disease-in-children-but-not-early-surgery
#7
EDITORIAL
Cortney R Ballengee, Subra Kugathasan
No abstract text is available yet for this article.
May 15, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29775794/rebleeding-vs-thromboembolism-after-hospitalization-for-gastrointestinal-bleeding-in-patients-on-direct-oral-anticoagulants
#8
Neil Sengupta, Ariela L Marshall, Blake A Jones, Sandra Ham, Elliot B Tapper
BACKGROUND AND AIMS: Little is known about outcomes of patients hospitalized for gastrointestinal bleeding (GIB) while they are taking direct oral anticoagulants (DOAC). We aimed to determine the frequency at which patients resume DOAC therapy following hospitalization for GIB in a real-world setting, and the risks and benefits. METHODS: We conducted a retrospective analysis of medical claims data from the Truven Health Marketscan Commercial Claims and Encounters Database, from January 1, 2010 through December 31, 2014...
May 15, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29775793/analysis-of-dna-methylation-at-specific-loci-in-stool-samples-detects-colorectal-cancer-and-high-grade-dysplasia-in-patients-with-inflammatory-bowel-disease
#9
John B Kisiel, Pasquale Klepp, Hatim T Allawi, William R Taylor, Maria Giakoumopoulos, Tamara Sander, Tracy C Yab, Bjorn A Moum, Graham P Lidgard, Stephan Brackmann, Douglas W Mahoney, Arne Roseth, David A Ahlquist
BACKGROUND & AIMS: Patients with inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), are at increased risk for colorectal cancer (CRC). Analyses of DNA methylation patterns in stool samples have been reported to detect CRC in patients with IBD. We sought to validate these findings in larger cohorts and assess the accuracy of analysis of DNA methylation patterns in stool for detection of CRC and high-grade dysplasia (HGD) normalized to methylation level at ZDHHC1...
May 15, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29775792/diagnostic-yield-from-screening-asymptomatic-individuals-at-high-risk-for-pancreatic-cancer-a-meta-analysis-of-cohort-studies
#10
Juan E Corral, Karl F Mareth, Douglas L Riegert-Johnson, Ananya Das, Michael B Wallace
BACKGROUND & AIMS: There have been few studies of abdominal imaging screening of individuals at high risk for pancreatic cancer (based on family history or genetic variants). We performed a meta-analysis of prospective cohort studies to determine the diagnostic yield and outcomes of abdominal imaging screening for asymptomatic individuals at high risk. METHODS: Through a systematic review of multiple electronic databases and conference proceedings through July 2017, we identified prospective cohort studies (>20 patients) of asymptomatic adults determined to be at high-risk of pancreatic cancer (lifetime risk >5%, including specific genetic-associated conditions) who were screened by endoscopic ultrasound (EUS) and/or magnetic resonance imaging (MRI) to detect pancreatic lesions...
May 15, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29775791/an-imaging-biomarker-for-assessing-hepatic-function-in-patients-with-primary-sclerosing-cholangitis
#11
Jennifer Schulze, Henrike Lenzen, Jan B Hinrichs, Burckhardt Ringe, Michael P Manns, Frank Wacker, Kristina I Ringe
BACKGROUND & AIMS: We aimed to evaluate the potential of hepatobiliary phase magnetic resonance imaging (MRI) as parameter for assessment of hepatocellular function in patients with primary sclerosing cholangitis (PSC). METHODS: We collected data from 111 patients (83 male, 28 female; median, 44 years old), from March 2012 through March 2016, with a confirmed diagnosis of PSC who underwent MRI evaluation before and after injection (hepatobiliary phase) of a hepatocyte-specific contrast agent (gadoxetate disodium)...
May 15, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29775790/clinical-course-of-nodular-regenerative-hyperplasia-in-thiopurine-treated-inflammatory-bowel-disease-patients
#12
Melek Simsek, Berrie Meijer, Dewkoemar Ramsoekh, Gerd Bouma, Egbert-Jan van der Wouden, Bert den Hartog, Annemarie C de Vries, Frank Hoentjen, Gerard Dijkstra, Sybrand Y de Boer, Jeroen M Jansen, Andrea E van der Meulen, Ruud Beukers, Menno A Brink, Toos Steinhauser, Bas Oldenburg, Lennard P Gilissen, Ton H Naber, Marc A Verhagen, Nanne K H de Boer, Chris J J Mulder
No abstract text is available yet for this article.
May 15, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29753085/effects-of-virologic-response-to-treatment-on-short-and-long-term-outcomes-of-patients-with-chronic-hbv-infection-and-decompensated-cirrhosis
#13
Jeong Won Jang, Jong Young Choi, Young Seok Kim, Jeong-Ju Yoo, Hyun Young Woo, Sung Kyu Choi, Chung Hwan Jun, Chang Hyeong Lee, Joo Hyun Sohn, Won Young Tak, Yu Rim Lee, Kwang-Hyub Han
BACKGROUND & AIMS: Little is known about the effects of antiviral therapy on short- and long-term survival of patients with hepatitis B virus (HBV)-related decompensated cirrhosis. We aimed to determine whether a maintained virologic response (MVR, defined as persistent undetectable HBV DNA during therapy) associates with short-term (6-month) and long-term (6-120 months) survival of patients with decompensated cirrhosis. METHODS: We performed a 10-year observation analysis using data from the Epidemiology and Natural History of Liver Cirrhosis study of patients with decompensated liver cirrhosis in Korea...
May 9, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29753084/lorenz-curves-and-gini-coefficient-analyses-indicate-inefficiencies-in-esophageal-adenocarcinoma-screening
#14
Chin Hur, Tiannan Zhan, Aaron P Thrift, Thomas L Vaughan, Eric J Feuer
No abstract text is available yet for this article.
May 9, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29753083/level-of-hepatitis-b-hb-core-antibody-associates-with-seroclearance-of-hbv-dna-and-hb-surface-antigen-in-hb-e-antigen-seronegative-patients
#15
Hui-Han Hu, Jessica Liu, Chia-Ling Chang, Chin-Lan Jen, Mei-Hsuan Lee, Sheng-Nan Lu, Li-Yu Wang, Yuan Quan, Ning-Shao Xia, Chien-Jen Chen, Pei-Jer Chen, Hwai-I Yang
BACKGROUND & AIMS: Although a low level of hepatitis B surface antigen (HBsAg) is a marker of hepatitis B virus (HBV) seroclearance, additional biomarkers are needed for more accurate prediction. We investigated whether quantification of antibody against HBV core protein (anti-HBc) can identify patients with undetectable levels of HBV DNA and HBsAg seroclearance among those who were HBV e antigen (HBeAg)-seronegative. METHODS: We performed a retrospective analysis of data from a community-based cohort of individuals (30-65 years old) in Taiwan who were HBsAg seropositive, anti-HCV negative, and free of cirrhosis and or liver cancer, recruited from 1991 through 1992, and evaluated every 6-12 months until June 30, 2004...
May 9, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29753082/criteria-to-determine-reliability-of-non-invasive-assessment-of-liver-fibrosis-with-virtual-touch-quantification
#16
Jerome Boursier, Christophe Cassinotto, Gilles Hunault, Sarah Shili, Jerome Lebigot, Bruno Lapuyade, Adrien Lannes, Jean-Baptiste Hiriart, Victoire Cartier, Brigitte Le Bail, Sophie Michalak, Amaury Mouries, Frederic Oberti, Faiza Chermak, Isabelle Fouchard-Hubert, Paul Cales, Christophe Aube, Victor de Ledinghen
BACKGROUND & AIMS: Virtual Touch Quantification (VTQ) evaluates liver fibrosis in patients with chronic liver diseases by measuring shear wave speed in the liver. We aimed to determine the reliability criteria of VTQ examination. METHODS: We performed a prospective study of 1094 patients with chronic liver disease from November 2009 through October 2016 at Angers University Hospital, and between April 2010 and May 2015 at Bordeaux University Hospital, in France...
May 9, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29751167/efficacy-and-follow-up-of-sub-total-colectomy-with-ileo-rectal-anastomoses-in-patients-with-colitis-associated-neoplasia
#17
Noa Krugliak Cleveland, Jacob E Ollech, Ruben J Colman, Dylan Rodriquez, Ayal Hirsch, Russel D Cohen, Stephen B Hanauer, John Hart, Roger Hurst, David T Rubin
No abstract text is available yet for this article.
May 8, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29751166/safety-and-efficacy-of-combination-treatment-with-calcineurin-inhibitors-and-vedolizumab-in-patients-with-refractory-inflammatory-bowel-disease
#18
Britt Christensen, Peter Gibson, Dejan Micic, Ruben J Colman, Sarah R Goeppinger, Olufemmi Kassim, Andres Yarur, Christopher R Weber, Russell D Cohen, David T Rubin
BACKGROUND & AIMS: Little is known about the efficacy and safety of induction therapy with calcineurin inhibitors in combination with vedolizumab for patients with Crohn's disease (CD) or ulcerative colitis (UC). We analyzed the outcomes of patients receiving vedolizumab along with calcineurin inhibitors METHODS: We collected data on patients with CD (n=9) or UC (n=11) who began treatment with vedolizumab from May 20, 2014 through March 30, 2015 and received calcineurin inhibitors (tacrolimus or cyclosporin) during the first 12 months of vedolizumab therapy...
May 8, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29751165/no-association-between-consumption-of-sweetened-beverages-and-later-risk-of-crohn-s-disease-or-ulcerative-colitis
#19
Hamed Khalili, Niclas Hakansson, Simon S Chan, Jonas F Ludvigsson, Ola Olen, Andrew T Chan, Andrew R Hart, Alicja Wolk
BACKGROUND & AIMS: Consumption of sweetened beverages has been associated with inflammation, based on measurements of C-reactive protein and tumor necrosis factor, as well as immune-mediated disorders including rheumatoid arthritis. We investigated associations with Crohn's disease (CD) or ulcerative colitis (UC). METHODS: We conducted a prospective cohort study of 83,042 participants (44-83 years old) enrolled in the Cohort of Swedish Men or the Swedish Mammography Study...
May 8, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29730438/model-to-determine-the-optimal-dietary-elimination-strategy-for-treatment-of-eosinophilic-esophagitis
#20
Tiannan Zhan, Ayman Ali, Jin G Choi, Minyi Lee, John Leung, Evan S Dellon, John J Garber, Chin Hur
BACKGROUND & AIMS: Elimination diets are effective treatments for eosinophilic esophagitis (EoE), but foods that activate esophagitis are identified empirically, via a process that involves multiple esophagogastroduodenoscopies (EGDs). No optimized approach has been developed to identify foods that activate EoE. We aimed to compare clinical strategies to provide data to guide treatment. METHODS: We developed a computer-based simulation model to determine the optimal empiric elimination strategy based on reported prevalence values for foods that activate EoE...
May 3, 2018: Clinical Gastroenterology and Hepatology
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