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Clinical Gastroenterology and Hepatology

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https://www.readbyqxmd.com/read/28238958/real-world-effectiveness-and-safety-of-oral-combination-antiviral-therapy-for-hepatitis-c-virus-genotype-4-infection
#1
Javier Crespo, Jose Luis Calleja, Inmaculada Fernández, Begoña Sacristan, Belén Ruiz-Antorán, Javier Ampuero, Marta Hernández-Conde, Javier García-Samaniego, Francisco Gea, Maria Buti, Joaquin Cabezas, Sabela Lens, Rosa Maria Morillas, Jose Ramon Salcines, Juan Manuel Pascasio, Juan Turnes, Federico Sáez-Royuela, Juan Arenas, Diego Rincón, Martin Prieto, Francisco Jorquera, Juan Jose Sanchez Ruano, Carmen A Navascués, Esther Molina, Adolfo Gallego Moya, José Maria Moreno-Planas
No abstract text is available yet for this article.
February 23, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28238957/temporal-trends-in-initiation-of-therapy-with-tumor-necrosis-factor-antagonists-for-patients-with-inflammatory-bowel-disease-a-population-based-analysis
#2
Laura E Targownik, Aruni Tenakaroon, Stella Leung, Lisa M Lix, Harminder Singh, Charles N Bernstein
BACKGROUND & AIMS: Anti-tumor necrosis factor (anti-TNF) agents are effective treatments for Crohn's disease (CD) and ulcerative colitis (UC). We aimed to determine their patterns of use and changes in these patterns over time, as well as use of immunomodulators and corticosteroids before anti-TNF therapy for persons with inflammatory bowel diseases (IBD). METHODS: We used the University of Manitoba IBD Epidemiology Database to identify all anti-TNF users with CD and UC from 2001 through 2014...
February 23, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28238956/serum-vitamin-d-and-risk-of-clinical-relapse-in-patients-with-ulcerative-colitis
#3
LETTER
Mayur Garg
No abstract text is available yet for this article.
February 23, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28238955/persistence-of-non-dysplastic-barrett-s-esophagus-is-not-protective-against-progression-to-adenocarcinoma
#4
Rajesh Krishnamoorthi, Guilherme Piovezani Ramos, Nicholas Crews, Michele Johnson, Ross Dierkhising, Qian Shi, Brenda Ginos, Kenneth Wang, David Katzka, Navtej Buttar, Prasad G Iyer
No abstract text is available yet for this article.
February 23, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28238954/histologic-normalization-occurs-in-ulcerative-colitis-and-is-associated-with-improved-clinical-outcomes
#5
Britt Christensen, Stephen B Hanauer, Jonathan Erlich, Olufemi Kassim, Peter R Gibson, Jerrold R Turner, John Hart, David T Rubin
BACKGROUND & AIMS: Mucosal healing, determined by histologic analysis, is a potential therapeutic target for patients with ulcerative colitis (UC). However, the histologic features of tissue normalization, as an outcome of treatment, have not been well described. We examined the prevalence and predictive values of normalization of the colonic mucosa, based on histologic analysis (histologic normalization) in patients with UC, and determined its association with risk of clinical relapse, compared to disease quiescence and mucosal healing...
February 23, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28238953/cost-effectiveness-of-screening-patients-with-gastroesophageal-reflux-disease-for-barrett-s-esophagus-with-a-minimally-invasive-cell-sampling-device
#6
Curtis R Heberle, Amir-Houshang Omidvari, Ayman Ali, Sonja Kroep, Chung Yin Kong, John M Inadomi, Joel H Rubenstein, Angela C Tramontano, Emily C Dowling, William D Hazelton, E Georg Luebeck, Iris Lansdorp-Vogelaar, Chin Hur
BACKGROUND & AIMS: It is important to identify patients with Barrett's esophagus (BE), the precursor to esophageal adenocarcinoma (EAC). Patients with BE are usually identified by endoscopy, which is expensive. The cytosponge, which collects tissue from the esophagus non-invasively, could be a cost-effective tool for screening individuals with gastroesophageal reflux disease (GERD), who are at increased risk for BE. We developed a model to analyze the cost effectiveness of using cytosponge in first-line screening of patients with GERD for BE with endoscopic confirmation, compared to endoscopy screening only, METHODS: We incorporated data from a large clinical trial of cytosponge performance into 2 validated microsimulation models of EAC progression (the esophageal adenocarcinoma model from the Massachusetts General Hospital and the microsimulation screening analysis model from Erasmus University Medical Center)...
February 23, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28238952/white-paper-aga-an-episode-of-care-framework-for-the-management-of-obesity-moving-towards-high-value-high-quality-care-a-report-from-the-american-gastroenterological-association-institute-obesity-episode-of-care-and-bundle-initiative-work-group
#7
Joel V Brill, Jamile A Ashmore, Matthew L Brengman, Daniel E Buffington, S David Feldshon, Kelli E Friedman, Peter S Margolis, Danielle Markus, Leslie Narramore, Amita Rastogi, Anthony A Starpoli, Kenneth Strople, Jane V White, Sarah E Streett
No abstract text is available yet for this article.
February 23, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28235574/gastrointestinal-surgery-and-endoscopy-recent-trends-in-competition-and-collaboration
#8
Gyorgy Baffy, P Marco Fisichella
No abstract text is available yet for this article.
February 21, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28235573/circumferential-jejunal-ulcers-an-unusual-manifestation-of-nonsteroidal-anti-inflammatory-drug-enteropathy
#9
Steve Hu, Daniel N Castresana, Tarun Rustagi
No abstract text is available yet for this article.
February 21, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28223206/accumulation-of-heavy-metals-in-people-on-a-gluten-free-diet
#10
Stephanie L Raehsler, Rok Seon Choung, Eric V Marietta, Joseph A Murray
BACKGROUND & AIMS: Specific foods such as fish and rice have high concentrations of metals such as arsenic, mercury, lead, cadmium, and cobalt. Many gluten-free diets (GFDs) include these foods, so we evaluated whether a GFD was associated with increased metal bioaccumulation. METHODS: We performed a population-based cross-sectional study using data collected from the National Health and Nutrition Examination Survey (NHANES), from 2009 through 2012, collecting information on the diagnosis of celiac disease and adherence to a GFD...
February 18, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28223205/yellow-colon-a-case-of-cryptosporidium-colitis
#11
Thanh-Truc Le, Mohammad Bilal, Gabriel Reep
No abstract text is available yet for this article.
February 18, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28223204/increases-in-ige-eosinophils-and-mast-cells-can-be-used-in-diagnosis-and-to-predict-relapse-of-igg4-related-disease
#12
Emma L Culver, Ross Sadler, Adrian C Bateman, Mateusz Makuch, Tamsin Cargill, Berne Ferry, Rob Aalberse, Eleanor Barnes, Theo Rispens
BACKGROUND & AIMS: Immunoglobulin G4-related disease (IgG4-RD) is characterized by increased serum levels of IgG4 and infiltration of biliary, and pancreatic, and other tissues by IgG4-positive plasma cells. We assessed the prevalence of allergy and/or atopy, serum and tissue IgE antibodies, and blood and tissue eosinophils in patients with IgG4-RD. We investigated the association between serum IgE and diagnosis and relapse of this disease. METHODS: We performed a prospective study of 48 patients with IgG4-RD, 42 patients with an increased serum level of IgG4 with other inflammatory and autoimmune conditions (disease controls), and 51 healthy individuals (healthy controls) recruited from Oxford, United Kingdom from March 2010 through March 2014, and followed for a median of 41 months (range 3-73 months)...
February 18, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28223203/indomethacin-and-short-duration-intravenous-hydration-as-a-more-feasible-regimen-for-risk-reduction-of-post-endoscopic-retrograde-cholangiopancreatography-pancreatitis
#13
LETTER
Jodie A Barkin, Jamie S Barkin
No abstract text is available yet for this article.
February 18, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28223202/green-sputum-from-a-patient-with-primary-sclerosing-cholangitis
#14
Gwen Thompson, William Sanchez, Douglas A Simonetto
No abstract text is available yet for this article.
February 18, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28223201/cryptosporidium-pouchitis
#15
Greg S Cohen, Robert J Schenck
No abstract text is available yet for this article.
February 18, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28223200/gastrointestinal-bleeding-caused-by-a-penetrating-aortic-ulcer
#16
Samuel Raimundo Fernandes, Carlos Noronha Ferreira, José Velosa
No abstract text is available yet for this article.
February 18, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28232073/effects-of-combination-therapy-with-immunomodulators-on-trough-levels-and-antibodies-against-tumor-necrosis-factor-antagonists-in-patients-with-inflammatory-bowel-disease-a-meta-analysis
#17
REVIEW
Yun Qiu, Ren Mao, Bai-Li Chen, Sheng-Hong Zhang, Jing Guo, Yao He, Zhi-Rong Zeng, Shomron Ben-Horin, Min-Hu Chen
BACKGROUND & AIMS: It is not clear whether combination therapy with immunomodulators affects the immunogenicity of tumor necrosis factor (TNF) antagonists in patients with inflammatory bowel disease (IBD). We performed a meta-analysis to quantify the effects of combined immunomodulator therapy on the presence of antibodies against TNF antagonists (anti-drug antibodies, ADAs) and trough levels of anti-TNF agents. METHODS: We systematically searched publication databases for studies that reported prevalence of ADAs in patients who received anti-TNF agents...
February 13, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28215616/incidence-and-determinants-of-hepatocellular-carcinoma-in-autoimmune-hepatitis-a-systematic-review-and-meta-analysis
#18
REVIEW
Aylin Tansel, Lior H Katz, Hashem B El-Serag, Aaron P Thrift, Mayur Parepally, Mohammad H Shakhatreh, Fasiha Kanwal
BACKGROUND: The risk of hepatocellular carcinoma (HCC) in patients with autoimmune hepatitis (AIH) is unclear. We conducted a systematic review and meta-analysis of the incidence of HCC and associated risk factors among patients with AIH. METHODS: We searched PubMed, Embase, and reference lists from relevant articles through June 2016 to identify cohort studies that examined the incidence of HCC in patients with AIH. We used random effects models to estimate pooled incidence rates overall and in subgroup of patients with cirrhosis...
February 12, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28215615/factors-associated-with-persistent-increase-in-level-of-alanine-aminotransferase-in-patients-with-chronic-hepatitis-b-receiving-oral-antiviral-therapy
#19
Ira M Jacobson, Mary K Washington, Maria Buti, Alexander Thompson, Nezam Afdhal, Robert Flisiak, Ulus Salih Akarca, Konstantin G Tchernev, John F Flaherty, Raul Aguilar Schall, Robert P Myers, G Mani Subramanian, John G McHutchison, Zobair Younossi, Patrick Marcellin, Keyur Patel
BACKGROUND & AIM: Despite complete suppression of viral DNA with antiviral agents, in some patients with chronic hepatitis B (CHB), serum levels of alanine aminotransferase (ALT) do not normalize. We investigated factors associated with persistent increases in level of ALT in patients with CHB given long-term tenofovir disoproxil fumarate. METHODS: We analyzed data from 471 hepatitis B e antigen (HBeAg)-positive and HBeAg-negative patients with CHB participating in 2 phase 3 trials...
February 12, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28199822/correction
#20
(no author information available yet)
No abstract text is available yet for this article.
February 12, 2017: Clinical Gastroenterology and Hepatology
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