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Clinical Gastroenterology and Hepatology

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https://www.readbyqxmd.com/read/28511956/adventures-of-an-aortic-graft-a-transduodenal-journey
#1
Ege Altan, Nomingerel Tseveldorj, Taylan Kav
No abstract text is available yet for this article.
May 13, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28511955/an-unusual-case-of-chronic-diarrhea-chronic-lymphocytic-leukemia-small-lymphocytic-lymphoma-with-colorectal-involvement
#2
Chencheng Xie, Khalil Aloreidi, Jorge Gilbert
No abstract text is available yet for this article.
May 13, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28502788/response-to-letter-patient-sex-reproductive-status-and-synthetic-hormone-use-associate-with-histologic-severity-of-nonalcoholic-steatohepatitis
#3
LETTER
Ju Dong Yang, Manal F Abdelmalek, Cynthia D Guy, Anna Mae Diehl, Ayako Suzuki
No abstract text is available yet for this article.
May 11, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28501538/biopsies-from-allograft-liver-contain-histologic-features-of-hepatitis-c-virus-infection-following-virus-eradication
#4
Emma Whitcomb, Won-Tak Choi, Keith R Jerome, Linda Cook, Charles Landis, Joseph Ahn, Helen S Te, Jamak Esfeh, Ibrahim A Hanouneh, Stephen C Rayhill, William Gibson, Thomas Plesec, Jamie Koo, Hanlin L Wang, John Hart, Rish K Pai, Maria Westerhoff
BACKGROUND & AIMS: Most patients, even those who have received liver transplants, achieve a sustained virologic response (SVR) to therapy for hepatitis C virus (HCV) infection. Little is known about the histologic features of liver biopsies collected following SVR, particularly in patients who have received liver transplants. We aimed to better characterize the histologic features of allograft liver biopsies from patients who achieved a SVR to anti-HCV therapy following liver transplantation...
May 10, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28501537/effects-of-exercise-on-liver-fat-and-metabolism-in-alcohol-drinkers
#5
David Houghton, Kate Hallsworth, Christian Thoma, Sophie Cassidy, Timothy Hardy, Sarah Heaps, Kieren G Hollingsworth, Roy Taylor, Christopher P Day, Steve Masson, Stuart McPherson, Quentin M Anstee, Michael I Trenell
BACKGROUND & AIMS: Exercise is an important component of obesity associated disorders and has been shown to reduce markers of non-alcoholic fatty liver disease (NAFLD). However, little is known about how these effects are influenced by alcohol intake. We performed a randomized controlled trial to investigate the effects of exercise on hepatic triglyceride content (HTGC) and metabolism in overweight or obese patients who consume alcohol. METHODS: We performed a prospective study of 27 patients (mean age 54±11years, body mass index [BMI], 31±4kg/m2) with >5% HTGC in the United Kingdom, consuming alcohol (mean 221±75 g/week)...
May 10, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28501536/multicenter-external-validation-of-risk-stratification-criteria-for-patients-with-variceal-bleeding
#6
Irene Conejo, Maria Anna Guardascione, Puneeta Tandon, Alba Cachero, Josep Castellote, Juan G Abraldes, Lucio Amitrano, Joan Genescà, Salvador Augustin
BACKGROUND & AIMS: Early placement of a transjugular intrahepatic porto-systemic shunts (TIPS) is considered the treatment of choice for patients with acute variceal bleeding (AVB) and cirrhosis who have a high risk of death (Child-Pugh class B with active bleeding at endoscopy or Child-Pugh class C). It has been proposed that patients of Child-Pugh class B, even with active bleeding, should not be considered high risk. Alternative criteria have been proposed for identification of high-risk patients, such as Child-Pugh class C with plasma level of creatinine of 1 mg/dl or more (ChildC-C1) and a model for end-stage liver disease (MELD) score of 19 or more...
May 10, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28501535/high-negative-predictive-value-low-prevalence-and-spectrum-effect-caution-in-the-interpretation
#7
EDITORIAL
Ruben Hernaez, Aaron P Thrift
No abstract text is available yet for this article.
May 10, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28501534/glomus-tumor-of-the-stomach-a-tumor-that-needs-to-be-differentiated-from-gastrointestinal-stromal-tumor
#8
Shuisheng Zhang, Jianwei Zhang, Chengfeng Wang
No abstract text is available yet for this article.
May 10, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28501533/promising-modalities-to-identify-and-monitor-eosinophilic-esophagitis
#9
Girish Hiremath, Sandeep K Gupta
Eosinophilic esophagitis (EoE) is an allergen-mediated condition characterized by symptoms of esophageal dysfunction and histological evidence of intense eosinophilic inflammation involving the esophagus in absence of overlapping conditions such as gastroesophageal reflux disease. Since the initial description as a distinct entity about two decades ago, there has been a remarkable rise in the recognition of this clinico-pathologic entity. Current approach to diagnose and monitor EoE requires repeated esophagogastroduodenoscopies (EGDs), with associated sedation/anesthesia, to visualize mucosal abnormalities, and to obtain multiple biopsies for histologic assessment and to evaluate treatment response...
May 10, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28479504/magnitude-and-kinetics-of-decrease-in-liver-stiffness-after-anti-viral-therapy-in-patients-with-chronic-hepatitis-c-a-systematic-review-and-meta-analysis
#10
REVIEW
Siddharth Singh, Antonio Facciorusso, Rohit Loomba, Yngve T Falck-Ytter
BACKGROUND & AIMS: We performed a systematic review and meta-analysis to estimate the decrease in liver stiffness, measured by vibration-controlled transient elastrography (VCTE), in patients with hepatitis C virus (HCV) infection who achieved a sustained virologic response (SVR). METHODS: We searched the literature through October 2016 for observational studies or randomized controlled trials of adults with HCV infection who received antiviral therapy (either direct acting antiviral agents or interferon-based therapies), underwent liver stiffness measurement using VCTE before starting therapy, and had at least 1 follow-up VCTE after completion of therapy; studies also provided data on mean or median liver stiffness measurements for patients who did and did not achieve an SVR...
May 4, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28479503/infliximab-vs-adalimumab-for-uc-is-there-a-difference
#11
EDITORIAL
Mark T Osterman, Gary R Lichtenstein
No abstract text is available yet for this article.
May 4, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28479502/statin-use-and-risk-of-cirrhosis-and-related-complications-in-patients-with-chronic-liver-diseases-a-systematic-review-and-meta-analysis
#12
REVIEW
Rebecca G Kim, Rohit Loomba, Larry J Prokop, Siddharth Singh
BACKGROUND & AIMS: Statins have been variably shown to decrease risk and complications of chronic liver diseases (CLDs). We performed a systematic review and meta-analysis to evaluate the association between statins and risk of cirrhosis and related complications in patients with CLDs. METHODS: Through a systematic literature search up to March 2017, we identified 13 studies (3 randomized trials, 10 cohort studies) in adults with CLDs, reporting the association between statin use and risk of development of cirrhosis, decompensated cirrhosis, improvements in portal hypertension, or mortality...
May 4, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28479501/porphyria-cutanea-tarda-as-the-initial-manifestation-of-subclinical-hereditary-hemochromatosis
#13
Oleksandr Trofymenko, Paul Sagerman, Drew Jb Kurtzman
No abstract text is available yet for this article.
May 4, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28479500/histologic-scores-for-fat-and-fibrosis-associate-with-development-of-type-2-diabetes-in-patients-with-non-alcoholic-fatty-liver-disease
#14
Karl Björkström, Per Stål, Rolf Hultcrantz, Hannes Hagström
BACKGROUND & AIMS: Non-alcoholic fatty liver disease (NAFLD) is a strong risk factor for development of type 2 diabetes, but little is known about how long-term NAFLD or its histologic features affect risk. We aimed to investigate the cumulative incidence of type 2 diabetes in patients with NAFLD, and to identify histologic factors that affect risk of diabetes. METHODS: We performed a retrospective study of 396 patients in Sweden diagnosed with NAFLD by biopsy analysis from 1971 through 2009 who did not have type 2 diabetes at baseline...
May 4, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28479499/reply-to-dr-gregersen
#15
LETTER
John Pandolfino, Ikuo Hirano, Guy Boeckxstaens
No abstract text is available yet for this article.
May 4, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28479498/ibs-in-ibd-a-label-to-stick-with-caution-authors-reply
#16
LETTER
David J Gracie, Christopher J M Williams, Ruchit Sood, Saqib Mumtaz, M Hassan Bholah, P John Hamlin, Alexander C Ford
No abstract text is available yet for this article.
May 4, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28478302/refractory-achalasia-is-poem-changing-the-paradigm
#17
EDITORIAL
Dhyanesh A Patel, Michael F Vaezi
No abstract text is available yet for this article.
May 3, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28478301/rare-case-of-hematemesis-calciphylaxsis-of-the-esophagus
#18
Archana Machavarapu, Thomas A Brown, Izuchukwu E Nwakoby
No abstract text is available yet for this article.
May 3, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28458009/do-shared-exposures-link-the-lungs-and-gut-association-between-asthma-and-inflammatory-bowel-disease
#19
EDITORIAL
Edward L Barnes, Michael D Kappelman
No abstract text is available yet for this article.
April 27, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28458008/risk-of-gastrointestinal-bleeding-in-patients-taking-non-vitamin-k-antagonist-oral-anticoagulants-a-systematic-review-and-meta-analysis
#20
Corey S Miller, Alastair Dorreen, Myriam Martel, Thao Huynh, Alan N Barkun
BACKGROUND AND AIMS: Non-vitamin K antagonist oral anticoagulants (NOACs) are convenient and effective in prevention and treatment of venous thromboembolism and prevention of stroke in patients with atrial fibrillation. However, these drugs have been associated with increased risk of gastrointestinal (GI) bleeding. We conducted a systematic review and meta-analysis to determine the risk of GI bleeding in patients receiving these drugs. METHODS: We searched the EMBASE, Medline, Cochrane, and ISI Web of knowledge databases through January 2016 for randomized trials that compared NOACs to conventional anticoagulants for approved indications...
April 27, 2017: Clinical Gastroenterology and Hepatology
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