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Clinical Gastroenterology and Hepatology

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https://www.readbyqxmd.com/read/28652128/the-esophageal-epithelial-barrier-in-health-and-disease
#1
Christopher H Blevins, Prasad G Iyer, Marcelo F Vela, David A Katzka
Dysfunction in the esophageal epithelial barrier function is a major source for morbidity. In order to better understand the pathophysiologic pathways of the diseases associated with barrier dysfunction, including gastroesophageal reflux disease (GERD), eosinophilic esophagitis (EoE), Barrett's esophagus (BE) and obesity, it is important to understand the esophageal epithelial embryologic development, microscopic anatomy with a special focus on the barrier structure and function, extra-epithelial defense mechanisms and how these change in the diseased state...
June 23, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28648398/insulin-expressing-pancreatic-neuroendocrine-tumor-associated-with-intratumor-amyloidosis
#2
Rohini R Vanga, Sadhna Dhingra, Kalpesh Patel
No abstract text is available yet for this article.
June 22, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28647459/aseptic-liver-abscess-induced-by-crohn-s-disease-successfully-treated-by-infliximab
#3
Yang Yang, Dongfeng Chen
No abstract text is available yet for this article.
June 21, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28647458/predictors-of-efficacy-of-percutaneous-tibial-nerve-stimulation-for-fecal-incontinence-a-post-hoc-analysis-of-a-randomized-trial
#4
Emma J Horrocks, Sami A Chadi, Natasha J Stevens, Steven D Wexner, Charles H Knowles
BACKGROUND AND AIMS: A recent UK multicentre, phase III trial [The CONFIDeNT Trial: Lancet 2015; 386: 1640-48], demonstrated no significant clinical benefit of percutaneous tibial nerve stimulation (PTNS) over sham stimulation; however this study did not analyse predictors of response. This study aimed to determine predictors of PTNS efficacy in adults with fecal incontinence (FI) using data from this randomized controlled trial. METHODS: The study population comprised 205 patients from the CONFIDeNT Trial, with original primary outcome (≥ 50% reduction in weekly FI episodes after 12 weeks of treatment) remaining the binary denominator of success or failure...
June 21, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28642206/obesity-and-risk-of-nafld-a-comparison-of-bioelectrical-impedance-analysis-and-conventional-derived-anthropometric-measures
#5
Maya Balakrishnan, Hashem B El-Serag, Theresa Nguyen, Jonathan Hilal, Fasiha Kanwal, Aaron P Thrift
No abstract text is available yet for this article.
June 19, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28642205/radial-endoscopic-ultrasound-for-the-diagnosis-of-chronic-schistosomiasis-in-the-colorectum
#6
Chun-Hua Zhou, Wei-Xia Zhou, Duan-Min Hu
No abstract text is available yet for this article.
June 19, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28634137/comparison-of-patterns-and-outcomes-of-liver-resection-for-hepatocellular-carcinoma-east-versus-west
#7
Tian Yang, Parissa Tabrizian, Han Zhang, Wan-Yee Lau, Jun Han, Zhen-Li Li, Zheng Wang, Meng-Chao Wu, Sander Florman, Myron E Schwartz, Feng Shen
No abstract text is available yet for this article.
June 17, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28634136/tongxie-formula-reduces-symptoms-of-irritable-bowel-syndrome
#8
Heng Fan, Liang Zheng, Yaoliang Lai, Weimin Lu, Zhixiang Yan, Qi Xiao, Baiwen Li, Min Tang, Dawei Huang, Yuanyuan Wang, Zhen Li, Yuwei Mei, Zhengyan Jiang, Xingxing Liu, Qing Tang, Dongmei Zuo, Jingyi Ye, Yongqiang Yang, Huisuo Huang, Zongxiang Tang, Jun Xiao
BACKGROUND & AIMS: Irritable bowel syndrome (IBS) is the most common chronic gastrointestinal disorder, yet few drugs are effective in reducing symptoms. Approximately 50% of patients with IBS attempt herbal therapy at least once. We performed a randomized controlled trial to compare the efficacy of the herb formulation tongxie vs placebo or pinaverium (an antispasmodic agent) in reducing symptoms of IBS. METHODS: We performed a trial of 1044 adult patients with IBS (based on Rome III criteria) at 5 hospitals in China, from August 2012 through January 2015...
June 17, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28634135/outcomes-and-role-of-urgent-endoscopy-in-high-risk-patients-with-acute-nonvariceal-gastrointestinal-bleeding
#9
Soo-Han Cho, Yoon-Seon Lee, Youn-Jung Kim, Chang Hwan Sohn, Shin Ahn, Dong-Woo Seo, Won Young Kim, Jae Ho Lee, Kyoung Soo Lim
BACKGROUND & AIMS: We investigated clinical outcomes in high-risk patients with acute nonvariceal upper gastrointestinal bleeding (UGIB), and determined if urgent endoscopy is effective. METHODS: Consecutive patients with Glasgow-Blatchford score >7 who underwent endoscopy for acute nonvariceal UGIB at the emergency department from January 1, 2005, to December 31, 2014, were included. Urgent (<6 h) and elective (6-48 h) endoscopies were defined according to the time to endoscopy after the initial presentation...
June 17, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28634134/a-terminal-rectal-mass-ultimately-identified-by-histopathology-examination
#10
Tao Shi, Li-Tian Wang, Gang Liu
No abstract text is available yet for this article.
June 17, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28634133/acute-severe-gastrointestinal-tract-bleeding-is-associated-with-an-increased-risk-of-thromboembolism-and-death
#11
Naoyoshi Nagata, Toshiyuki Sakurai, Takuro Shimbo, Shiori Moriyasu, Hidetaka Okubo, Kazuhiro Watanabe, Chizu Yokoi, Mikio Yanase, Junichi Akiyama, Naomi Uemura
BACKGROUND & AIMS: We performed a retrospective cohort study of patients with and without gastrointestinal bleeding (GIB) to determine whether GIB increases the risks of thromboembolism and death. METHODS: We collected data from 522 patients with acute severe GIB and 1044 patients without GIB (controls, matched for age, sex, year of diagnosis, history of thromboembolism, and use of antithrombotic drugs) who underwent endoscopy at the National Center for Global Health and Medicine in Japan from January 2009 through December 2014...
June 17, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28634132/diagnosis-of-autoimmune-pancreatitis-the-evolution-of-diagnostic-criteria-for-a-rare-disease
#12
Suresh T Chari
No abstract text is available yet for this article.
June 17, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28634131/cost-effectiveness-of-pre-versus-post-liver-transplant-hepatitis-c-treatment-with-direct-acting-antivirals
#13
Sumeyye Samur, Brian Kues, Turgay Ayer, Mark S Roberts, Fasiha Kanwal, Chin Hur, Drew Michael S Donnell, Raymond T Chung, Jagpreet Chhatwal
BACKGROUND & AIMS: Oral direct-acting antivirals (DAAs) for hepatitis C virus (HCV) treatment offer new hope to both pre- and post-liver transplant (LT) patients. However, whether to treat HCV patients pre- versus post-LT is not clear, as treatment can improve liver function but could reduce the chance of receiving a LT while on the waiting list. Our objective was to evaluate the cost-effectiveness of pre-LT versus post-LT HCV treatment with oral DAAs in decompensated cirrhotic patients on the LT waiting list...
June 17, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28625817/natural-history-of-adult-ulcerative-colitis-in-population-based-cohorts-a-systematic-review
#14
Mathurin Fumery, Siddharth Singh, Parambir S Dulai, Corinne Gower-Rousseau, Laurent Peyrin-Biroulet, William J Sandborn
INTRODUCTION: A comprehensive knowledge of the natural history of UC helps understand disease evolution, identify poor prognostic markers and impact of treatment strategies and facilitates shared decision-making. We systematically reviewed the natural history of UC in adult population-based cohort studies with long-term follow-up. MATERIALS AND METHODS: Through a systematic literature review of MEDLINE through March 31, 2016, we identified 60 studies performed in 17 population-based inception cohorts reporting the long-term course and outcomes of adult-onset UC (n=15,316 UC patients)...
June 15, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28625816/a-prospective-multicenter-study-evaluating-learning-curves-and-competence-in-endoscopic-ultrasound-and-endoscopic-retrograde-cholangiopancreatography-among-advanced-endoscopy-trainees-the-rapid-assessment-of-trainee-endoscopy-skills-rates-study
#15
Sachin Wani, Rajesh Keswani, Matt Hall, Samuel Han, Meer Akbar Ali, Brian Brauer, Linda Carlin, Amitabh Chak, Dan Collins, Gregory A Cote, David L Diehl, Christopher J DiMaio, Andrew Dries, Ihab El-Hajj, Swan Ellert, Kimberley Fairley, Ashley Faulx, Larissa Fujii-Lau, Srinivas Gaddam, Seng-Ian Gan, Jonathan P Gaspar, Chitiki Gautamy, Stuart Gordon, Cynthia Harris, Sarah Hyder, Ross Jones, Stephen Kim, Srinadh Komanduri, Ryan Law, Linda Lee, Rawad Mounzer, Daniel Mullady, V Raman Muthusamy, Mojtaba Olyaee, Patrick Pfau, Shreyas Saligram, Cyrus Piraka, Amit Rastogi, Laura Rosenkranz, Fadi Rzouq, Aditi Saxena, Raj J Shah, Violette C Simon, Aaron Small, Jayaprakash Sreenarasimhaiah, Andrew Walker, Andrew Y Wang, Rabindra R Watson, Robert H Wilson, Patrick Yachimski, Dennis Yang, Steven Edmundowicz, Dayna S Early
BACKGROUND AND AIMS: Based on the Next Accreditation System, trainee assessment should occur on a continuous basis with individualized feedback. We aimed to validate endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) learning curves among advanced endoscopy trainees (AETs) using a large national sample of training programs and to develop a centralized database that allows assessment of performance in relation to peers. METHODS: ASGE recognized training programs were invited to participate and AETs were graded on ERCP and EUS exams using a validated competency assessment tool that assesses technical and cognitive competence in a continuous fashion...
June 15, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28625815/risk-of-pneumonia-caused-by-pneumocystis-jirovecii-in-inflammatory-bowel-disease-the-role-of-concomitant-pulmonary-comorbidities
#16
LETTER
Fabio Salvatore Macaluso, Mario Cottone, Ambrogio Orlando
No abstract text is available yet for this article.
June 15, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28624652/association-of-transferrin-saturation-with-the-arthropathy-of-hereditary-haemochromatosis
#17
EDITORIAL
N L Whalen, J K Olynyk
No abstract text is available yet for this article.
June 14, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28624651/efficacy-and-optimal-duration-of-metallic-stent-in-the-management-of-refractory-anastomotic-stricture-after-liver-transplantation
#18
Sunguk Jang, Mansour A Parsi, Rocio Lopez, Amit Bhatt, John J Vargo
BACKGROUND: Anastomotic bile duct stricture (ABS) remains as one of the most common complications in liver transplant patients. Current practice of endoscopic retrograde cholangiopancreatography (ERCP) with insertion of plastic stent (PS) often requires multiple procedures before achieving stricture resolution. To date, studies utilizing covered self-expandable metallic stent (cSEMS) in ABS management reported varying degree of efficacy. The aim of this study was to analyze long term efficacy of cSEMS in patients with ABS, and identifying factor(s) influencing the probability of stricture resolution...
June 14, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28624650/colon-pathology-characteristics-in-li-fraumeni-syndrome
#19
William Rengifo-Cam, Hailey M Shepherd, Kory W Jasperson, N Jewel Samadder, Wade Samowitz, Sheryl R Tripp, Joshua D Schiffman, Wendy Kohlmann
No abstract text is available yet for this article.
June 14, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28624649/diffuse-enlargement-of-the-pancreas-an-unusual-radiologic-presentation-of-a-pancreatic-neuroendocrine-tumor
#20
Oscar Santes, Jesús Morales-Maza, Ismael Domínguez-Rosado
No abstract text is available yet for this article.
June 14, 2017: Clinical Gastroenterology and Hepatology
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