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Clinical Gastroenterology and Hepatology

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https://www.readbyqxmd.com/read/27923723/fecal-microbiota-transplantation-for-recurrent-clostridium-difficile-infection-in-patients-with-inflammatory-bowel-disease-a-single-center-experience
#1
Samantha M Chin, Jenny Sauk, Jasmine Mahabamunuge, Jess L Kaplan, Elizabeth L Hohmann, Hamed Khalili
No abstract text is available yet for this article.
December 3, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27923722/-reverse-double-wire-cannulation-of-the-pancreatic-duct
#2
LETTER
Steven Shamah, Patrick Okolo
No abstract text is available yet for this article.
December 3, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27923721/occult-hepatitis-b-and-risk-of-reactivation-after-hepatitis-c-treatment-with-direct-acting-antivirals
#3
LETTER
Resat Ozaras, Bilgul Mete, Fehmi Tabak
No abstract text is available yet for this article.
December 3, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27923720/a-case-of-upper-gastrointestinal-bleeding-caused-by-gastric-tuberculosis
#4
Vishal Sharma, Surinder S Rana, Priya Singh
No abstract text is available yet for this article.
December 3, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27923719/predicting-costs-of-care-for-patients-with-inflammatory-bowel-diseases
#5
EDITORIAL
Benjamin Click, Alyce M Anderson, David G Binion
No abstract text is available yet for this article.
December 3, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27916678/incidence-risk-factors-and-outcomes-of-colorectal-cancer-in-patients-with-ulcerative-colitis-with-low-grade-dysplasia-a-systematic-review-and-meta-analysis
#6
REVIEW
Mathurin Fumery, Parambir S Dulai, Samir Gupta, Larry J Prokop, Sonia Ramamoorthy, William J Sandborn, Siddharth Singh
BACKGROUND & AIMS: Little is known about outcomes of patients with ulcerative colitis with low-grade dysplasia (UC-LGD). We estimated the incidence of and risk factors for progression to colorectal cancer (CRC) in cohorts of patients with UC-LGD who underwent surveillance (surveillance cohort), and the prevalence of dysplasia-related findings among patients who underwent colectomy for UC-LGD (surgical cohort). METHODS: We performed a systematic literature review through June 1, 2016 to identify cohort studies of adults with UC-LGD...
December 1, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27913244/higher-risk-of-hospitalization-and-serious-infection-among-patients-with-ulcerative-colitis-treated-with-adalimumab-compared-with-infliximab-in-a-nationwide-study
#7
Siddharth Singh, Nynne Nyboe Andersen, Mikael Andersson, Edward V Loftus, Tine Jess
BACKGROUND & AIMS: We compared the effectiveness and safety of infliximab and adalimumab in biologic-naïve patients with ulcerative colitis (UC), in a nationwide register-based propensity score-matched study of patients in Denmark. METHODS: We collected data from 1719 adults with UC, 15-75 years old, in Denmark who were treated with either infliximab or adalimumab as their first biologic agent. We compared rates of all-cause hospitalization, UC-related hospitalization, major abdominal surgery, and serious infections after a variable 2:1 propensity score matching, accounting for baseline clinical characteristics, disease severity, healthcare use, and use of UC-related medications...
November 29, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27913243/the-top-five-reasons-you-should-publish-in-cgh
#8
EDITORIAL
Fasiha Kanwal, Hashem El-Serag
No abstract text is available yet for this article.
November 29, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27913242/gallbladder-vasculitis-an-unexpected-and-puzzling-finding
#9
Miguel F Carrascosa, Rafael Daroca-Pérez, Mary Silva-Carmona
No abstract text is available yet for this article.
November 29, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27890854/association-between-low-trough-levels-of-vedolizumab-during-induction-therapy-for-inflammatory-bowel-diseaseswith-need-for-additional-doses-within-6-months
#10
Nicolas Williet, Gilles Boschetti, Marion Fovet, Thomas Di Bernado, Pierre Claudez, Emilie Del Tedesco, Camille Jarlot, Leslie Rinaldi, Anne Berger, Jean-Marc Phelip, Bernard Flourie, Stéphane Nancey, Stéphane Paul, Xavier Roblin
BACKGROUND & AIMS: We investigated whether serum trough levels of vedolizumab, a humanized monoclonal antibody against integrin alpha 4 beta 7, during the induction phase of treatment can determine whether patients will need additional doses (optimization of therapy) within the first 6 months. METHODS: We conducted an observational study of 47 consecutive patients with Crohn's disease (CD; n=31) or ulcerative colitis (UC; n=16) who had not responded to 2 previous treatment regimens with antagonists of tumor necrosis factor and were starting therapy with vedolizumab at 2 hospitals in France, from June 2014 through April 2016...
November 24, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27890853/chromoendoscopy-for-surveillance-in-ulcerative-colitis-and-crohn-s-disease-a-systematic-review-of-randomized-trials
#11
REVIEW
Andrea Iannone, Marinella Ruospo, Germaine Wong, Mariabeatrice Principi, Michele Barone, Giovanni Fm Strippoli, Alfredo Di Leo
BACKGROUND & AIMS: Key international guideline agencies recommend dysplasia surveillance in inflammatory bowel diseases with chromoendoscopy. We performed a systematic review of randomized trials comparing chromoendoscopy versus other endoscopic techniques for dysplasia surveillance in inflammatory bowel diseases. METHODS: We searched MEDLINE, EMBASE and Cochrane Central Register of Controlled Trials for relevant studies published through September 2016. We estimated risk ratios (RR) for dichotomous outcomes (all-cause/colorectal cancer-related mortality, time to interval cancer, patients with dysplasia, total/subtypes of dysplastic lesions, dysplasia detected by targeted biopsies, adverse events), mean differences (MD) for continuous outcomes (procedural time, costs, total/targeted biopsies) and their 95% confidence intervals (CI) using a random-effects model...
November 24, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27890852/adenocarcinoma-arising-from-an-end-ileostomy-in-a-patient-with-familial-adenomatous-polyposis-fap
#12
Justin T Huntington, Peter P Stanich, Alan E Harzman
No abstract text is available yet for this article.
November 24, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27876607/an-unusual-case-of-pain-in-the-gallbladder-area-is-it-acute-cholecystitis
#13
Ruiguo Zhang, Jian Tan, Qiang Jia
No abstract text is available yet for this article.
November 19, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27876606/devastating-peristomal-pyoderma-gangrenosum-challenges-in-diagnosis-and-management
#14
James W T Toh, Ian Whiteley
No abstract text is available yet for this article.
November 19, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27856366/advanced-stage-colorectal-cancer-in-persons-younger-than-50-years-not-associated-with-longer-duration-of-symptoms-or-time-to-diagnosis
#15
Frank W Chen, Vandana Sundaram, Thomas A Chew, Uri Ladabaum
BACKGROUND & AIMS: The incidence of colorectal cancer (CRC) is increasing in the United States (US) among adults under the age of 50 years. Studies of young-onset CRC have focused on outcomes and treatment patterns. We examined patient presentation, provider evaluation, and time to diagnosis, which can affect stage and prognosis. METHODS: In a retrospective study, we collected data from patients with a diagnosis of colorectal adenocarcinoma, confirmed by pathologists, seen at the Stanford Cancer Institute from January 1, 2008 through December 31, 2014...
November 14, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27856365/use-of-intestinal-ultrasound-to-monitor-crohn-s-disease-activity
#16
Torsten Kucharzik, Bianca M Wittig, Ulf Helwig, Norbert Börner, Alexander Rössler, Stefan Rath, Christian Maaser
BACKGROUND & AIMS: We performed a multicenter study to determine whether transabdominal bowel wall ultrasonography, a non-invasive procedure that does not require radiation, can be used to monitor progression of Crohn's disease (CD). METHODS: We performed a 12-month prospective, non-interventional study at 47 sites in Germany, from December 2010 through September 2014. Our study included 234 adult patients with CD who experienced a flare, defined as Harvey-Bradshaw index score of ≥7...
November 14, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27856364/incidence-and-prevalence-of-crohn-s-disease-and-ulcerative-colitis-in-olmsted-county-minnesota-from-1970-through-2010
#17
Raina Shivashankar, William J Tremaine, W Scott Harmsen, Edward V Loftus
BACKGROUND & AIMS: The incidence and prevalence of inflammatory bowel diseases (IBD) continue to increase worldwide. We sought to update incidence rates of Crohn's disease (CD) and ulcerative colitis (UC) in a well-defined United States (US) population, calculating values for Olmsted County, Minnesota through 2010. We also calculated prevalence values. METHODS: The resources of the Rochester Epidemiology Project were used to identify county residents who were diagnosed with IBD (CD or UC), based on previously set criteria...
November 14, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27856363/rectal-gas-volume-measured-by-computerized-tomography-identifies-evacuation-disorders-in-patients-with-constipation
#18
Seon-Young Park, Disha Khemani, Alfred D Nelson, Deborah Eckert, Michael Camilleri
BACKGROUND & AIMS: Approximately one-third of patients who present with constipation to gastroenterology care have rectal evacuation disorders. We aimed to compare rectal gas volume, measured by computerized tomography (CT), in constipated patients with and without rectal evacuation disorders. METHOD: In a retrospective study, we collected data from 1553 patients with constipation, evaluated over 20 years. We analyzed data from 141 patients evaluated by anorectal manometry, balloon expulsion tests, and colon transit tests, collecting records of abdominal and pelvic CT examinations...
November 14, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27856362/colonic-transit-and-bile-acid-synthesis-or-excretion-in-patients-with-irritable-bowel-syndrome-diarrhea-without-bile-acid-malabsorption
#19
Cédric Peleman, Michael Camilleri, Irene Busciglio, Duane Burton, Leslie Donato, Alan R Zinsmeister
: bile acid malabsorption (BAM). BAs are passively absorbed to a different extent along the mammalian colon, so that levels are lower in the feces than in proximal colon. Our aim was to explore associations among total, primary, and secretory BA in stool and colonic transit in patients with irritable bowel syndrome-diarrhea (IBS-D) without overt BAM. METHODS: In a cross-sectional observational study of 116 patients with IBS-D recruited from local communities in Minnesota, we measured total and individual main fecal BA excretion, fecal fat and fecal weight over 48 hrs, fasting serum levels of C4 (surrogate for BA synthesis), and overall colonic transit by scintigraphy (geometric center at 24 hrs and 48 hrs)...
November 14, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27847281/identification-of-pediatric-patients-with-celiac-disease-based-on-serology-and-a-classification-and-regression-tree-analysis
#20
Anna Ermarth, Matthew Bryce, Stephanie Woodward, Gregory Stoddard, Linda Book, M Kyle Jensen
BACKGROUND & AIMS: Celiac disease is detected using serology and endoscopy analyses. We used multiple statistical analyses of a geographically isolated population in the United States to determine whether a single serum screening can identify individuals with celiac disease. METHODS: We performed a retrospective study of 3555 pediatric patients (18 years old or younger) in the intermountain West region of the United States from January 1, 2008 through September 30, 2013...
November 12, 2016: Clinical Gastroenterology and Hepatology
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