journal
MENU ▼
Read by QxMD icon Read
search

Cancer

journal
https://www.readbyqxmd.com/read/28915338/neurocognitive-psychosocial-and-quality-of-life-outcomes-in-adult-survivors-of-childhood-non-hodgkin-lymphoma
#1
Matthew J Ehrhardt, Daniel A Mulrooney, Chenghong Li, Malek J Baassiri, Kari Bjornard, John T Sandlund, Tara M Brinkman, I-Chan Huang, Deo Kumar Srivastava, Kirsten K Ness, Leslie L Robison, Melissa M Hudson, Kevin R Krull
BACKGROUND: Children with non-Hodgkin lymphoma (NHL) undergo treatment with central nervous system-directed therapy, the potentially neurotoxic effects of which have not been reported in NHL survivors. METHODS: NHL survivors (n = 187) participating in the St. Jude Lifetime Cohort who were 10 or more years from their diagnosis and were 18 years old or older underwent neurocognitive, emotional distress (Brief Symptom Inventory 18), and health-related quality of life (HRQOL) assessments (36-Item Short Form Health Survey)...
September 15, 2017: Cancer
https://www.readbyqxmd.com/read/28915337/the-cost-and-cost-effectiveness-of-childhood-cancer-treatment-in-el-salvador-central-america-a-report-from-the-childhood-cancer-2030-network
#2
Soad Fuentes-Alabi, Nickhill Bhakta, Roberto Franklin Vasquez, Sumit Gupta, Susan E Horton
BACKGROUND: Although previous studies have examined the cost of treating individual childhood cancers in low-income and middle-income countries, to the authors' knowledge none has examined the overall cost and cost-effectiveness of operating a childhood cancer treatment center. Herein, the authors examined the cost and sources of financing of a pediatric cancer unit in Hospital Nacional de Ninos Benjamin Bloom in El Salvador, and make estimates of cost-effectiveness. METHODS: Administrative data regarding costs and volumes of inputs were obtained for 2016 for the pediatric cancer unit...
September 15, 2017: Cancer
https://www.readbyqxmd.com/read/28914983/suggesting-the-cytologic-diagnosis-of-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-niftp-a-retrospective-analysis-of-atypical-and-suspicious-nodules
#3
Kyle C Strickland, Brooke E Howitt, Justine A Barletta, Edmund S Cibas, Jeffrey F Krane
BACKGROUND: The term "noninvasive follicular thyroid neoplasm with papillary-like nuclear features" (NIFTP) has replaced a subset of follicular variant of papillary thyroid carcinoma due to the indolent behavior of such tumors. NIFTPs are most often classified in an "indeterminate" diagnostic category. In the current study, the authors sought to identify cytologic features helpful in distinguishing NIFTP from other entities in these categories, particularly benign nodules. METHODS: The authors retrospectively evaluated a consecutive cohort of 130 thyroid fine-needle aspiration (FNA) specimens with an indeterminate diagnosis and available histopathologic follow-up...
September 15, 2017: Cancer
https://www.readbyqxmd.com/read/28914981/fna-cytology-of-solitary-fibrous-tumors-and-the-diagnostic-value-of-stat6-immunocytochemistry
#4
Edneia Tani, Johan Wejde, Kristina Åström, Inga-Lill Wingmo, Olle Larsson, Felix Haglund
BACKGROUND: Solitary fibrous tumors (SFTs) are rare mesenchymal tumors commonly located in the pleura, soft tissues, or meninges and are characterized by the NGFI-A-binding protein 2 (NAB2)-signal transducer and activator of transcription 6 (STAT6) fusion gene. Recent studies have indicated that nuclear STAT6 immunohistochemistry is a specific marker for SFTs. METHODS: The authors reviewed fine-needle aspiration (FNA) specimens from extracranial SFTs diagnosed at their institution between 1993 and 2017...
September 15, 2017: Cancer
https://www.readbyqxmd.com/read/28902468/fine-needle-aspiration-of-lipoblastoma-cytological-molecular-and-clinical-features
#5
Joana Ferreira, Gonçalo Esteves, Ricardo Fonseca, Carmo Martins, Saudade André, Maria Manuel Lemos
BACKGROUND: Lipoblastomas are rare, benign adipocytic tumors that present mostly during infancy. In about 70% of cases, these tumors carry abnormalities in chromosome 8, mainly leading to rearrangements of the PLAG1 gene. METHODS: We report a series of histologically proven lipoblastomas with previous fine-needle aspiration (FNA) cytology from 9 patients (n = 10 samples) and describe their clinical, cytological, and molecular features. RESULTS: Our cohort included 5 boys and 4 girls (median age, 2...
September 13, 2017: Cancer
https://www.readbyqxmd.com/read/28902465/a-modified-reporting-approach-for-thyroid-fna-in-the-niftp-era-a-1-year-institutional-experience
#6
Jeffrey K Mito, Erik K Alexander, Trevor E Angell, Justine A Barletta, Matthew A Nehs, Edmund S Cibas, Jeffrey F Krane
BACKGROUND: The reclassification of noninvasive follicular variant of papillary thyroid carcinoma as noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) has created diagnostic and management issues for thyroid fine-needle aspiration (FNA). In response to these challenges, the authors' laboratory adopted a NIFTP policy including 1) stringent criteria (requiring pseudo-inclusions, papillae, and/or psammoma bodies) for a malignant diagnosis of papillary carcinoma to limit false-positive results due to NIFTP and 2) the use of explanatory notes in cases with cytomorphologic features suggestive of possible NIFTP to encourage lobectomy over thyroidectomy...
September 13, 2017: Cancer
https://www.readbyqxmd.com/read/28902404/quality-of-life-after-surgery-for-intracranial-meningioma
#7
Luke S Benz, Margaret R Wrensch, Joellen M Schildkraut, Melissa L Bondy, Joshua L Warren, Joseph L Wiemels, Elizabeth B Claus
BACKGROUND: To the authors' knowledge, limited data exist regarding long-term quality of life (QOL) for patients diagnosed with intracranial meningioma. METHODS: The data in the current study concerned 1722 meningioma cases diagnosed among residents of Connecticut, Massachusetts, California, Texas, and North Carolina from May 1, 2006 through March 14, 2013, and 1622 controls who were frequency matched to the cases by age, sex, and geography. These individuals were participants in a large, population-based, case-control study...
September 13, 2017: Cancer
https://www.readbyqxmd.com/read/28902402/safety-net-versus-private-hospital-setting-for-brain-metastasis-patients-treated-with-radiosurgery-alone-disparities-in-follow-up-care-and-outcomes
#8
Kevin Diao, Yanqing Sun, Stella K Yoo, Cheng Yu, Jason C Ye, Nicholas Trakul, Richard L Jennelle, Paul E Kim, Gabriel Zada, John P Gruen, Eric L Chang
BACKGROUND: Stereotactic radiosurgery (SRS) alone is an increasingly accepted treatment for brain metastases, but it requires adherence to frequently scheduled follow-up neuroimaging because of the risk of distant brain metastasis. The effect of disparities in access to follow-up care on outcomes after SRS alone is unknown. METHODS: This retrospective study included 153 brain metastasis patients treated consecutively with SRS alone from 2010 through 2016 at an academic medical center and a safety-net hospital (SNH) located in Los Angeles, California...
September 13, 2017: Cancer
https://www.readbyqxmd.com/read/28902401/variation-in-the-use-of-active-surveillance-for-low-risk-prostate-cancer
#9
Björn Löppenberg, David F Friedlander, Anna Krasnova, Andrew Tam, Jeffrey J Leow, Paul L Nguyen, Hawa Barry, Stuart R Lipsitz, Mani Menon, Firas Abdollah, Jesse D Sammon, Maxine Sun, Toni K Choueiri, Adam S Kibel, Quoc-Dien Trinh
BACKGROUND: This study assessed the use of active surveillance in men with low-risk prostate cancer and evaluated institutional factors associated with the receipt of active surveillance. METHODS: A retrospective, hospital-based cohort of 115,208 men with low-risk prostate cancer diagnosed between 2010 and 2014 was used. Multivariate and mixed effects models were used to examine variation and factors associated with active surveillance. RESULTS: During the study period, the use of active surveillance increased from 6...
September 13, 2017: Cancer
https://www.readbyqxmd.com/read/28902391/parental-distress-6-months-after-a-pediatric-cancer-diagnosis-in-relation-to-family-psychosocial-risk-at-diagnosis
#10
Sasja A Schepers, Simone M Sint Nicolaas, Heleen Maurice-Stam, Lotte Haverman, Chris M Verhaak, Martha A Grootenhuis
BACKGROUND: This study was aimed at assessing fathers' and mothers' distress 6 months after a pediatric cancer diagnosis and at determining whether this is related to the level of family psychosocial risk 1 month after the diagnosis. METHODS: A sample of 192 families completed the electronic Psychosocial Assessment Tool (ePAT) 1 month after the diagnosis. At 6 months after the diagnosis, 119 mothers and 98 fathers completed the Distress Thermometer for Parents (DT-P; of which n=132 had also completed the ePAT at baseline)...
September 13, 2017: Cancer
https://www.readbyqxmd.com/read/28902390/outcomes-in-adolescents-and-young-adults-with-hodgkin-lymphoma-treated-on-us-cooperative-group-protocols-an-adult-intergroup-e2496-and-children-s-oncology-group-cog-ahod0031-comparative-analysis
#11
Tara O Henderson, Susan K Parsons, Kristen E Wroblewski, Lu Chen, Fangxin Hong, Sonali M Smith, Jennifer L McNeer, Ranjana H Advani, Randy D Gascoyne, Louis S Constine, Sandra Horning, Nancy L Bartlett, Bijal Shah, Joseph M Connors, John I Leonard, Brad S Kahl, Kara M Kelly, Cindy L Schwartz, Hongli Li, Jonathan W Friedberg, Debra L Friedman, Leo I Gordon, Andrew M Evens
BACKGROUND: There is no clear consensus between pediatric and adult providers about the treatment of adolescents and young adults (AYAs) with Hodgkin lymphoma (HL). METHODS: Failure-free survival (FFS) and overall survival (OS) were compared between 114 patients ages 17 to 21 years with HL who were treated on the Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Intergroup adult E2496 study and 391 similarly patients ages 17 to 21 years with HL who were treated on the pediatric Children's Oncology Group (COG) AHOD0031 study...
September 13, 2017: Cancer
https://www.readbyqxmd.com/read/28898394/diagnostic-accuracy-of-serum-antibodies-to-human-papillomavirus-type-16-early-antigens-in-the-detection-of-human-papillomavirus-related-oropharyngeal-cancer
#12
Kristina R Dahlstrom, Karen S Anderson, Matthew S Field, Diego Chowell, Jing Ning, Nan Li, Qingyi Wei, Guojun Li, Erich M Sturgis
BACKGROUND: Because of the current epidemic of human papillomavirus (HPV)-related oropharyngeal cancer (OPC), a screening strategy is urgently needed. The presence of serum antibodies to HPV-16 early (E) antigens is associated with an increased risk for OPC. The purpose of this study was to evaluate the diagnostic accuracy of antibodies to a panel of HPV-16 E antigens in screening for OPC. METHODS: This case-control study included 378 patients with OPC, 153 patients with nonoropharyngeal head and neck cancer (non-OPC), and 782 healthy control subjects...
September 12, 2017: Cancer
https://www.readbyqxmd.com/read/28892280/costs-of-alk-ros1-egfr-and-kras-testing-in-non-small-cell-lung-cancer-about-different-strategies-in-france
#13
LETTER
Laetitia Lambros, Briac Guibourg, Arnaud Uguen
No abstract text is available yet for this article.
September 11, 2017: Cancer
https://www.readbyqxmd.com/read/28892267/reply-to-costs-of-alk-ros1-egfr-and-kras-testing-in-non-small-cell-lung-cancer-about-different-strategies-in-france
#14
LETTER
Giancarlo Troncone
No abstract text is available yet for this article.
September 11, 2017: Cancer
https://www.readbyqxmd.com/read/28891067/the-effect-of-health-insurance-on-childhood-cancer-survival-in-the-united-states
#15
Jong Min Lee, Xiaoyan Wang, Rohit P Ojha, Kimberly J Johnson
BACKGROUND: The effect of health insurance on childhood cancer survival has not been well studied. Using Surveillance, Epidemiology, and End Results (SEER) data, this study was designed to assess the association between health insurance status and childhood cancer survival. METHODS: Data on cancers diagnosed among children less than 15 years old from 2007 to 2009 were obtained from the SEER 18 registries. The effect of health insurance at diagnosis on 5-year childhood cancer mortality was estimated with marginal survival probabilities, restricted mean survival times, and Cox proportional hazards (PH) regression analyses, which were adjusted for age, sex, race/ethnicity, and county-level poverty...
September 11, 2017: Cancer
https://www.readbyqxmd.com/read/28885778/histopathologic-follow-up-and-hpv-test-results-with-hsil-papanicolaou-test-results-in-china-s-largest-academic-women-s-hospital
#16
Xiang Tao, R Marshall Austin, Hao Zhang, Lihong Zhang, Jianan Xiao, Xianrong Zhou, Li Wang, Chengquan Zhao
BACKGROUND: Cervical cancer screening in China is largely limited to occasional opportunistic screening in urban centers. The current study reports histopathologic follow-up and human papillomavirus (HPV) results in women with high-grade squamous intraepithelial lesion (HSIL) Papanicolaou (Pap) tests reported at the largest academic women's hospital in China and compares these findings with those of published Western studies among frequently screened women. METHODS: A retrospective cohort study documented HSIL Pap tests, patient age, HPV results, and histopathologic follow-up from 2011 through 2015 in the Obstetrics and Gynecology Hospital of Fudan University (OGHFU) in Shanghai, China...
September 8, 2017: Cancer
https://www.readbyqxmd.com/read/28885766/computer-assisted-cytologic-diagnosis-in-pancreatic-fna-an-application-of-neural-networks-to-image-analysis
#17
Amir Momeni-Boroujeni, Elham Yousefi, Jonathan Somma
BACKGROUND: Fine-needle aspiration (FNA) biopsy is an accurate method for the diagnosis of solid pancreatic masses. However, a significant number of cases still pose a diagnostic challenge. The authors have attempted to design a computer model to aid in the diagnosis of these biopsies. METHODS: Images were captured of cell clusters on ThinPrep slides from 75 pancreatic FNA cases (20 malignant, 24 benign, and 31 atypical). A K-means clustering algorithm was used to segment the cell clusters into separable regions of interest before extracting features similar to those used for cytomorphologic assessment...
September 8, 2017: Cancer
https://www.readbyqxmd.com/read/28885712/pathological-complete-response-in-patients-with-esophageal-cancer-after-the-trimodality-approach-the-association-with-baseline-variables-and-survival-the-university-of-texas-md-anderson-cancer-center-experience
#18
Mariela Blum Murphy, Lianchum Xiao, Viren R Patel, Dipen M Maru, Arlene M Correa, Fatemeh G Amlashi, Zhongxing Liao, Ritsuko Komaki, Steven H Lin, Heath D Skinner, Ara Vaporciyan, Garrett L Walsh, Stephen G Swisher, Boris Sepesi, Jeffrey H Lee, Manoop S Bhutani, Brian Weston, Wayne L Hofstetter, Jaffer A Ajani
BACKGROUND: Reports are limited regarding clinical and pretreatment features that might predict a pathological complete response (pathCR) after treatment in patients with esophageal cancer (EC). This might allow patient selection for different strategies. This study examines the association of a pathCR with pretreatment variables, overall survival (OS), recurrence-free survival (RFS), and patterns of recurrence in a large cohort from a single institution. METHODS: The baseline clinical features of 911 consecutive patients with EC who were treated with trimodality therapy from January 2000 to November 2013 were analyzed...
September 8, 2017: Cancer
https://www.readbyqxmd.com/read/28885707/physical-function-metric-over-measure-an-illustration-with-the-patient-reported-outcomes-measurement-information-system-promis-and-the-functional-assessment-of-cancer-therapy-fact
#19
Aaron J Kaat, Benjamin D Schalet, Joshua Rutsohn, Roxanne E Jensen, David Cella
BACKGROUND: Measuring patient-reported outcomes (PROs) is becoming an integral component of quality improvement initiatives, clinical care, and research studies in cancer, including comparative effectiveness research. However, the number of PROs limits comparability across studies. Herein, the authors attempted to link the Functional Assessment of Cancer Therapy-General Physical Well-Being (FACT-G PWB) subscale with the Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function (PF) calibrated item bank...
September 8, 2017: Cancer
https://www.readbyqxmd.com/read/28885700/historical-time-to-disease-progression-and-progression-free-survival-in-patients-with-recurrent-refractory-neuroblastoma-treated-in-the-modern-era-on-children-s-oncology-group-early-phase-trials
#20
Wendy B London, Rochelle Bagatell, Brenda J Weigel, Elizabeth Fox, Dongjing Guo, Collin Van Ryn, Arlene Naranjo, Julie R Park
BACKGROUND: Early-phase trials in patients with recurrent neuroblastoma historically used an objective "response" of measureable disease (Response Evaluation Criteria In Solid Tumors [RECIST], without bone/bone marrow assessment) to select agents for further study. Historical cohorts may be small and potentially biased; to the authors' knowledge, disease recurrence studies from international registries are outdated. Using a large recent cohort of patients with recurrent/refractory neuroblastoma from Children's Oncology Group (COG) modern-era early-phase trials, the authors determined outcome and quantified parameters for designing future studies...
September 8, 2017: Cancer
journal
journal
20067
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"