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CA: a Cancer Journal for Clinicians

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https://www.readbyqxmd.com/read/29028110/melanoma-staging-evidence-based-changes-in-the-american-joint-committee-on-cancer-eighth-edition-cancer-staging-manual
#1
Jeffrey E Gershenwald, Richard A Scolyer, Kenneth R Hess, Vernon K Sondak, Georgina V Long, Merrick I Ross, Alexander J Lazar, Mark B Faries, John M Kirkwood, Grant A McArthur, Lauren E Haydu, Alexander M M Eggermont, Keith T Flaherty, Charles M Balch, John F Thompson
Answer questions and earn CME/CNE To update the melanoma staging system of the American Joint Committee on Cancer (AJCC) a large database was assembled comprising >46,000 patients from 10 centers worldwide with stages I, II, and III melanoma diagnosed since 1998. Based on analyses of this new database, the existing seventh edition AJCC stage IV database, and contemporary clinical trial data, the AJCC Melanoma Expert Panel introduced several important changes to the Tumor, Nodes, Metastasis (TNM) classification and stage grouping criteria...
October 13, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29023645/higher-cigarette-pricing-encourages-older-smokers-to-quit
#2
Lara C Pullen
No abstract text is available yet for this article.
October 10, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29023627/falls-and-disability-among-female-cancer-survivors
#3
Lara C Pullen
No abstract text is available yet for this article.
October 10, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28972651/breast-cancer-statistics-2017-racial-disparity-in-mortality-by-state
#4
Carol E DeSantis, Jiemin Ma, Ann Goding Sauer, Lisa A Newman, Ahmedin Jemal
In this article, the American Cancer Society provides an overview of female breast cancer statistics in the United States, including data on incidence, mortality, survival, and screening. Approximately 252,710 new cases of invasive breast cancer and 40,610 breast cancer deaths are expected to occur among US women in 2017. From 2005 to 2014, overall breast cancer incidence rates increased among Asian/Pacific Islander (1.7% per year), non-Hispanic black (NHB) (0.4% per year), and Hispanic (0.3% per year) women but were stable in non-Hispanic white (NHW) and American Indian/Alaska Native (AI/AN) women...
October 3, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28961314/key-issues-surrounding-the-health-impacts-of-electronic-nicotine-delivery-systems-ends-and-other-sources-of-nicotine
#5
REVIEW
Jeffrey Drope, Zachary Cahn, Rosemary Kennedy, Alex C Liber, Michal Stoklosa, Rosemarie Henson, Clifford E Douglas, Jacqui Drope
Answer questions and earn CME/CNE Over the last decade, the use of electronic nicotine delivery systems (ENDS), including the electronic cigarette or e-cigarette, has grown rapidly. More youth now use ENDS than any tobacco product. This extensive research review shows that there are scientifically sound, sometimes competing arguments about ENDS that are not immediately and/or completely resolvable. However, the preponderance of the scientific evidence to date suggests that current-generation ENDS products are demonstrably less harmful than combustible tobacco products such as conventional cigarettes in several key ways, including by generating far lower levels of carcinogens and other toxic compounds than combustible products or those that contain tobacco...
September 29, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28961310/treatment-of-renal-cell-carcinoma-current-status-and-future-directions
#6
Pedro C Barata, Brian I Rini
Answer questions and earn CME/CNE Over the past 12 years, medical treatment for renal cell carcinoma (RCC) has transitioned from a nonspecific immune approach (in the cytokine era), to targeted therapy against vascular endothelial growth factor (VEGF), and now to novel immunotherapy agents. Multiple agents-including molecules against vascular endothelial growth factor, platelet-derived growth factor, and related receptors; inhibitors of other targets, such as the mammalian target of rapamycin and the MET and AXL tyrosine-protein kinase receptors; and an immune-checkpoint inhibitor-have been approved based on significant activity in patients with advanced RCC...
September 29, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28914965/reviewer-acknowledgment-2017
#7
(no author information available yet)
No abstract text is available yet for this article.
September 15, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28881380/missed-therapeutic-and-prevention-opportunities-in-women-with-brca-mutated-epithelial-ovarian-cancer-and-their-families-due-to-low-referral-rates-for-genetic-counseling-and-brca-testing-a-review-of-the-literature
#8
Paul J Hoskins, Walter H Gotlieb
Answer questions and earn CME/CNE Fifteen percent of women with epithelial ovarian cancer have inherited mutations in the BRCA breast cancer susceptibility genes. Knowledge of her BRCA status has value both for the woman and for her family. A therapeutic benefit exists for the woman with cancer, because a new family of oral drugs, the poly ADP-ribose polymerase (PARP) inhibitors, has recently been approved, and these drugs have the greatest efficacy in women who carry the mutation. For her family, there is the potential to prevent ovarian cancer in those carrying the mutation by using risk-reducing surgery...
September 7, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28763097/obesity-and-adverse-breast-cancer-risk-and-outcome-mechanistic-insights-and-strategies-for-intervention
#9
REVIEW
Manuel Picon-Ruiz, Cynthia Morata-Tarifa, Janeiro J Valle-Goffin, Eitan R Friedman, Joyce M Slingerland
Answer questions and earn CME/CNE Recent decades have seen an unprecedented rise in obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than 1.9 billion adults were overweight (body mass index [BMI], 25-29.9 kg/m(2) ), and of these, over 600 million were obese (BMI ≥30 kg/m(2) ). Although the association between obesity and the risk of diabetes and coronary artery disease is widely known, the impact of obesity on cancer incidence, morbidity, and mortality is not fully appreciated...
September 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28753241/the-importance-of-immunization-in-cancer-prevention-treatment-and-survivorship
#10
REVIEW
Elizabeth M Ward, Christopher R Flowers, Ted Gansler, Saad B Omer, Robert A Bednarczyk
Answer questions and earn CME/CNE A measles outbreak originating in California during 2014 and 2015 called attention to the potential for infectious disease outbreaks related to underimmunized populations in the United States and the potential risk to pediatric patients with cancer attending school when such outbreaks occur. Compliance with vaccine recommendations is important for the prevention of hepatitis B-related and human papillomavirus-related cancers and for protecting immunocompromised patients with cancer, and these points are often overlooked, resulting in the continued occurrence of vaccine-preventable neoplastic and infectious diseases and complications...
September 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28738442/charting-the-future-of-cancer-health-disparities-research-a-position-statement-from-the-american-association-for-cancer-research-the-american-cancer-society-the-american-society-of-clinical-oncology-and-the-national-cancer-institute
#11
Blase N Polite, Lucile L Adams-Campbell, Otis W Brawley, Nina Bickell, John M Carethers, Christopher R Flowers, Margaret Foti, Scarlett Lin Gomez, Jennifer J Griggs, Christopher S Lathan, Christopher I Li, J Leonard Lichtenfeld, Worta McCaskill-Stevens, Electra D Paskett
No abstract text is available yet for this article.
September 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28731537/frailty-and-cancer-implications-for-oncology-surgery-medical-oncology-and-radiation-oncology
#12
REVIEW
Cecilia G Ethun, Mehmet A Bilen, Ashesh B Jani, Shishir K Maithel, Kenneth Ogan, Viraj A Master
Answer questions and earn CME/CNE The concept of frailty has become increasingly recognized as one of the most important issues in health care and health outcomes and is of particular importance in patients with cancer who are receiving treatment with surgery, chemotherapy, and radiotherapy. Because both cancer itself, as well as the therapies offered, can be significant additional stressors that challenge a patient's physiologic reserve, the incidence of frailty in older patients with cancer is especially high-it is estimated that over one-half of older patients with cancer have frailty or prefrailty...
September 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28697273/evidence-supports-the-use-of-multidisciplinary-team-meetings
#13
Lara C Pullen
No abstract text is available yet for this article.
September 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28697271/encouraging-long-term-outcomes-reported-in-patients-with-stage-i-non-small-cell-lung-cancer-treated-with-stereotactic-ablative-radiotherapy
#14
Mary Kay Barton
No abstract text is available yet for this article.
September 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28683174/the-oncologic-burden-of-hepatitis-c-virus-infection-a-clinical-perspective
#15
REVIEW
Harrys A Torres, Terri Lynn Shigle, Nassim Hammoudi, James T Link, Felipe Samaniego, Ahmed Kaseb, Vincent Mallet
Answer questions and earn CME/CNE Chronic hepatitis C virus (HCV) infection affects millions of people worldwide and is associated with cancer. Direct-acting antivirals (DAAs) have changed HCV treatment paradigms, but little is known about the management of HCV infection in patients with cancer. The substantial burden of HCV infection and the inconclusive evidence regarding its detection and management in patients with cancer prompted the authors to review the literature and formulate recommendations. Patients for whom HCV screening is recommended included all patients with hematologic malignancies, hematopoietic cell transplantation candidates, and patients with liver cancer...
September 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28689371/erratum-breast-cancer-major-changes-in-the-american-joint-committee-on-cancer-eighth-edition-cancer-staging-manual
#16
(no author information available yet)
No abstract text is available yet for this article.
July 8, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28586094/disparities-in-liver-cancer-occurrence-in-the-united-states-by-race-ethnicity-and-state
#17
Farhad Islami, Kimberly D Miller, Rebecca L Siegel, Stacey A Fedewa, Elizabeth M Ward, Ahmedin Jemal
Liver cancer is highly fatal, and death rates in the United States are increasing faster than for any other cancer, having doubled since the mid-1980s. In 2017, it is estimated that the disease will account for about 41,000 new cancer cases and 29,000 cancer deaths in the United States. In this article, data from the Surveillance, Epidemiology, and End Results (SEER) Program and the National Center for Health Statistics are used to provide an overview of liver cancer incidence, mortality, and survival rates and trends, including data by race/ethnicity and state...
July 8, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28556024/cancer-of-the-esophagus-and-esophagogastric-junction-major-changes-in-the-american-joint-committee-on-cancer-eighth-edition-cancer-staging-manual
#18
Thomas W Rice, Donna M Gress, Deepa T Patil, Wayne L Hofstetter, David P Kelsen, Eugene H Blackstone
Answer questions and earn CME/CNE New to the eighth edition of the American Joint Committee on Cancer (AJCC) Cancer Staging Manual for epithelial cancers of the esophagus and esophagogastric junction are separate, temporally related cancer classifications: 1) before treatment decision (clinical); 2) after esophagectomy alone (pathologic); and 3) after preresection therapy followed by esophagectomy (postneoadjuvant pathologic). The addition of clinical and postneoadjuvant pathologic stage groupings was driven by a lack of correspondence of survival, and thus prognosis, between both clinical and postneoadjuvant pathologic cancer categories (facts about the cancer) and pathologic categories...
July 8, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28548692/primary-tumor-location-found-to-impact-prognosis-and-response-to-therapy-in-patients-with-metastatic-colorectal-cancer
#19
EDITORIAL
Mary Kay Barton
No abstract text is available yet for this article.
July 8, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28548681/symptoms-cancer-related-distress-and-overall-distress-may-contribute-to-racial-disparities-in-the-outcomes-of-patients-with-early-stage-breast-cancer
#20
Mary Kay Barton
No abstract text is available yet for this article.
July 8, 2017: CA: a Cancer Journal for Clinicians
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