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CA: a Cancer Journal for Clinicians

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https://www.readbyqxmd.com/read/28763097/obesity-and-adverse-breast-cancer-risk-and-outcome-mechanistic-insights-and-strategies-for-intervention
#1
REVIEW
Manuel Picon-Ruiz, Cynthia Morata-Tarifa, Janeiro J Valle-Goffin, Eitan R Friedman, Joyce M Slingerland
Answer questions and earn CME/CNE Recent decades have seen an unprecedented rise in obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than 1.9 billion adults were overweight (body mass index [BMI], 25-29.9 kg/m(2) ), and of these, over 600 million were obese (BMI ≥30 kg/m(2) ). Although the association between obesity and the risk of diabetes and coronary artery disease is widely known, the impact of obesity on cancer incidence, morbidity, and mortality is not fully appreciated...
August 1, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28753241/the-importance-of-immunization-in-cancer-prevention-treatment-and-survivorship
#2
REVIEW
Elizabeth M Ward, Christopher R Flowers, Ted Gansler, Saad B Omer, Robert A Bednarczyk
Answer questions and earn CME/CNE A measles outbreak originating in California during 2014 and 2015 called attention to the potential for infectious disease outbreaks related to underimmunized populations in the United States and the potential risk to pediatric patients with cancer attending school when such outbreaks occur. Compliance with vaccine recommendations is important for the prevention of hepatitis B-related and human papillomavirus-related cancers and for protecting immunocompromised patients with cancer, and these points are often overlooked, resulting in the continued occurrence of vaccine-preventable neoplastic and infectious diseases and complications...
July 28, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28738442/charting-the-future-of-cancer-health-disparities-research-a-position-statement-from-the-american-association-for-cancer-research-the-american-cancer-society-the-american-society-of-clinical-oncology-and-the-national-cancer-institute
#3
Blase N Polite, Lucile L Adams-Campbell, Otis W Brawley, Nina Bickell, John M Carethers, Christopher R Flowers, Margaret Foti, Scarlett Lin Gomez, Jennifer J Griggs, Christopher S Lathan, Christopher I Li, J Leonard Lichtenfeld, Worta McCaskill-Stevens, Electra D Paskett
No abstract text is available yet for this article.
July 24, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28731537/frailty-and-cancer-implications-for-oncology-surgery-medical-oncology-and-radiation-oncology
#4
REVIEW
Cecilia G Ethun, Mehmet A Bilen, Ashesh B Jani, Shishir K Maithel, Kenneth Ogan, Viraj A Master
Answer questions and earn CME/CNE The concept of frailty has become increasingly recognized as one of the most important issues in health care and health outcomes and is of particular importance in patients with cancer who are receiving treatment with surgery, chemotherapy, and radiotherapy. Because both cancer itself, as well as the therapies offered, can be significant additional stressors that challenge a patient's physiologic reserve, the incidence of frailty in older patients with cancer is especially high-it is estimated that over one-half of older patients with cancer have frailty or prefrailty...
July 21, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28697273/evidence-supports-the-use-of-multidisciplinary-team-meetings
#5
Lara C Pullen
No abstract text is available yet for this article.
July 11, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28697271/encouraging-long-term-outcomes-reported-in-patients-with-stage-i-non-small-cell-lung-cancer-treated-with-stereotactic-ablative-radiotherapy
#6
Mary Kay Barton
No abstract text is available yet for this article.
July 11, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28683174/the-oncologic-burden-of-hepatitis-c-virus-infection-a-clinical-perspective
#7
Harrys A Torres, Terri Lynn Shigle, Nassim Hammoudi, James T Link, Felipe Samaniego, Ahmed Kaseb, Vincent Mallet
Answer questions and earn CME/CNE Chronic hepatitis C virus (HCV) infection affects millions of people worldwide and is associated with cancer. Direct-acting antivirals (DAAs) have changed HCV treatment paradigms, but little is known about the management of HCV infection in patients with cancer. The substantial burden of HCV infection and the inconclusive evidence regarding its detection and management in patients with cancer prompted the authors to review the literature and formulate recommendations. Patients for whom HCV screening is recommended included all patients with hematologic malignancies, hematopoietic cell transplantation candidates, and patients with liver cancer...
July 6, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28689371/erratum-breast-cancer-major-changes-in-the-american-joint-committee-on-cancer-eighth-edition-cancer-staging-manual
#8
(no author information available yet)
No abstract text is available yet for this article.
July 8, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28586094/disparities-in-liver-cancer-occurrence-in-the-united-states-by-race-ethnicity-and-state
#9
Farhad Islami, Kimberly D Miller, Rebecca L Siegel, Stacey A Fedewa, Elizabeth M Ward, Ahmedin Jemal
Liver cancer is highly fatal, and death rates in the United States are increasing faster than for any other cancer, having doubled since the mid-1980s. In 2017, it is estimated that the disease will account for about 41,000 new cancer cases and 29,000 cancer deaths in the United States. In this article, data from the Surveillance, Epidemiology, and End Results (SEER) Program and the National Center for Health Statistics are used to provide an overview of liver cancer incidence, mortality, and survival rates and trends, including data by race/ethnicity and state...
July 8, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28556024/cancer-of-the-esophagus-and-esophagogastric-junction-major-changes-in-the-american-joint-committee-on-cancer-eighth-edition-cancer-staging-manual
#10
Thomas W Rice, Donna M Gress, Deepa T Patil, Wayne L Hofstetter, David P Kelsen, Eugene H Blackstone
Answer questions and earn CME/CNE New to the eighth edition of the American Joint Committee on Cancer (AJCC) Cancer Staging Manual for epithelial cancers of the esophagus and esophagogastric junction are separate, temporally related cancer classifications: 1) before treatment decision (clinical); 2) after esophagectomy alone (pathologic); and 3) after preresection therapy followed by esophagectomy (postneoadjuvant pathologic). The addition of clinical and postneoadjuvant pathologic stage groupings was driven by a lack of correspondence of survival, and thus prognosis, between both clinical and postneoadjuvant pathologic cancer categories (facts about the cancer) and pathologic categories...
July 8, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28548692/primary-tumor-location-found-to-impact-prognosis-and-response-to-therapy-in-patients-with-metastatic-colorectal-cancer
#11
EDITORIAL
Mary Kay Barton
No abstract text is available yet for this article.
July 8, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28548681/symptoms-cancer-related-distress-and-overall-distress-may-contribute-to-racial-disparities-in-the-outcomes-of-patients-with-early-stage-breast-cancer
#12
Mary Kay Barton
No abstract text is available yet for this article.
July 8, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28542893/the-burden-of-rare-cancers-in-the-united-states
#13
Carol E DeSantis, Joan L Kramer, Ahmedin Jemal
There are limited published data on the burden of rare cancers in the United States. By using data from the North American Association of Central Cancer Registries and the Surveillance, Epidemiology, and End Results program, the authors provide information on incidence rates, stage at diagnosis, and survival for more than 100 rare cancers (defined as an incidence of fewer than 6 cases per 100,000 individuals per year) in the United States. Overall, approximately 20% of patients with cancer in the United States are diagnosed with a rare cancer...
July 8, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28481406/the-role-of-the-microbiome-in-cancer-development-and-therapy
#14
REVIEW
Aadra P Bhatt, Matthew R Redinbo, Scott J Bultman
Answer questions and earn CME/CNE The human body harbors enormous numbers of microbiota that influence cancer susceptibility, in part through their prodigious metabolic capacity and their profound influence on immune cell function. Microbial pathogens drive tumorigenesis in 15% to 20% of cancer cases. Even larger numbers of malignancies are associated with an altered composition of commensal microbiota (dysbiosis) based on microbiome studies using metagenomic sequencing. Although association studies cannot distinguish whether changes in microbiota are causes or effects of cancer, a causative role is supported by rigorously controlled preclinical studies using gnotobiotic mouse models colonized with one or more specific bacteria...
July 8, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28319263/a-review-of-family-caregiving-intervention-trials-in-oncology
#15
REVIEW
Betty Ferrell, Elaine Wittenberg
This article contains a review of literature published from 2010 to 2016 on family caregiving in oncology. An analysis of 810 citations resulted in 50 randomized trials. These trials describe the need to prepare family caregivers for the complex role they play in cancer care. Several studies have demonstrated improved quality of life for family caregivers and improved emotional support from interventions. Several studies addressed communication and relational intimacy, which are key concerns. An additional focus of these trials was in the area of caregiving tasks and ways to diminish the burden of caregiving and preparedness for this role...
July 8, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28294295/breast-cancer-major-changes-in-the-american-joint-committee-on-cancer-eighth-edition-cancer-staging-manual
#16
Armando E Giuliano, James L Connolly, Stephen B Edge, Elizabeth A Mittendorf, Hope S Rugo, Lawrence J Solin, Donald L Weaver, David J Winchester, Gabriel N Hortobagyi
Answer questions and earn CME/CNE The revision of the eighth edition of the primary tumor, lymph node, and metastasis (TNM) classification of the American Joint Commission of Cancer (AJCC) for breast cancer was determined by a multidisciplinary team of breast cancer experts. The panel recognized the need to incorporate biologic factors, such as tumor grade, proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression prognostic panels into the staging system...
July 8, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28436999/clinical-practice-guidelines-on-the-evidence-based-use-of-integrative-therapies-during-and-after-breast-cancer-treatment
#17
REVIEW
Heather Greenlee, Melissa J DuPont-Reyes, Lynda G Balneaves, Linda E Carlson, Misha R Cohen, Gary Deng, Jillian A Johnson, Matthew Mumber, Dugald Seely, Suzanna M Zick, Lindsay M Boyce, Debu Tripathy
Answer questions and earn CME/CNE Patients with breast cancer commonly use complementary and integrative therapies as supportive care during cancer treatment and to manage treatment-related side effects. However, evidence supporting the use of such therapies in the oncology setting is limited. This report provides updated clinical practice guidelines from the Society for Integrative Oncology on the use of integrative therapies for specific clinical indications during and after breast cancer treatment, including anxiety/stress, depression/mood disorders, fatigue, quality of life/physical functioning, chemotherapy-induced nausea and vomiting, lymphedema, chemotherapy-induced peripheral neuropathy, pain, and sleep disturbance...
May 6, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28272812/evidence-accumulates-indicating-periodontal-disease-as-a-risk-factor-for-colorectal-cancer-or-lymphoma
#18
EDITORIAL
Mary Kay Barton
No abstract text is available yet for this article.
May 6, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28272802/health-behaviors-not-significantly-changed-by-direct-to-consumer-genetic-testing
#19
EDITORIAL
Mary Kay Barton
No abstract text is available yet for this article.
May 6, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28248415/colorectal-cancer-statistics-2017
#20
Rebecca L Siegel, Kimberly D Miller, Stacey A Fedewa, Dennis J Ahnen, Reinier G S Meester, Afsaneh Barzi, Ahmedin Jemal
Colorectal cancer (CRC) is one of the most common malignancies in the United States. Every 3 years, the American Cancer Society provides an update of CRC incidence, survival, and mortality rates and trends. Incidence data through 2013 were provided by the Surveillance, Epidemiology, and End Results program, the National Program of Cancer Registries, and the North American Association of Central Cancer Registries. Mortality data through 2014 were provided by the National Center for Health Statistics. CRC incidence rates are highest in Alaska Natives and blacks and lowest in Asian/Pacific Islanders, and they are 30% to 40% higher in men than in women...
May 6, 2017: CA: a Cancer Journal for Clinicians
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