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CA: a Cancer Journal for Clinicians

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https://www.readbyqxmd.com/read/29194581/hodgkin-lymphoma-a-review-and-update-on-recent-progress
#1
REVIEW
Satish Shanbhag, Richard F Ambinder
Hodgkin lymphoma (HL) is a unique hematopoietic neoplasm characterized by cancerous Reed-Sternberg cells in an inflammatory background. Patients are commonly diagnosed with HL in their 20s and 30s, and they present with supradiaphragmatic lymphadenopathy, often with systemic B symptoms. Even in advanced-stage disease, HL is highly curable with combination chemotherapy, radiation, or combined-modality treatment. Although the same doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapeutic regimen has been the mainstay of therapy over the last 30 years, risk-adapted approaches have helped de-escalate therapy in low-risk patients while intensifying treatment for higher risk patients...
December 1, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29165798/weight-management-and-physical-activity-throughout-the-cancer-care-continuum
#2
Wendy Demark-Wahnefried, Kathryn H Schmitz, Catherine M Alfano, Jennifer R Bail, Pamela J Goodwin, Cynthia A Thomson, Don W Bradley, Kerry S Courneya, Christie A Befort, Crystal S Denlinger, Jennifer A Ligibel, William H Dietz, Melinda R Stolley, Melinda L Irwin, Marcas M Bamman, Caroline M Apovian, Bernardine M Pinto, Kathleen Y Wolin, Rachel M Ballard, Andrew J Dannenberg, Elizabeth G Eakin, Matt M Longjohn, Susan D Raffa, Lucile L Adams-Campbell, Joanne S Buzaglo, Sharyl J Nass, Greta M Massetti, Erin P Balogh, Elizabeth S Kraft, Anand K Parekh, Darshak M Sanghavi, G Stephen Morris, Karen Basen-Engquist
Mounting evidence suggests that weight management and physical activity (PA) improve overall health and well being, and reduce the risk of morbidity and mortality among cancer survivors. Although many opportunities exist to include weight management and PA in routine cancer care, several barriers remain. This review summarizes key topics addressed in a recent National Academies of Science, Engineering, and Medicine workshop entitled, "Incorporating Weight Management and Physical Activity Throughout the Cancer Care Continuum...
November 22, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29160902/proportion-and-number-of-cancer-cases-and-deaths-attributable-to-potentially-modifiable-risk-factors-in-the-united-states
#3
Farhad Islami, Ann Goding Sauer, Kimberly D Miller, Rebecca L Siegel, Stacey A Fedewa, Eric J Jacobs, Marjorie L McCullough, Alpa V Patel, Jiemin Ma, Isabelle Soerjomataram, W Dana Flanders, Otis W Brawley, Susan M Gapstur, Ahmedin Jemal
Contemporary information on the fraction of cancers that potentially could be prevented is useful for priority setting in cancer prevention and control. Herein, the authors estimate the proportion and number of invasive cancer cases and deaths, overall (excluding nonmelanoma skin cancers) and for 26 cancer types, in adults aged 30 years and older in the United States in 2014, that were attributable to major, potentially modifiable exposures (cigarette smoking; secondhand smoke; excess body weight; alcohol intake; consumption of red and processed meat; low consumption of fruits/vegetables, dietary fiber, and dietary calcium; physical inactivity; ultraviolet radiation; and 6 cancer-associated infections)...
November 21, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29155450/risk-of-ovarian-function-recovery-should-be-considered-when-switching-from-treatment-with-adjuvant-tamoxifen-to-aromatase-inhibitor-therapy-in-women-with-chemotherapy-induced-amenorrhea
#4
https://www.readbyqxmd.com/read/29155447/older-adults-may-not-consider-life-expectancy-an-important-factor-in-cancer-screening
#5
Clement Chung
No abstract text is available yet for this article.
November 20, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29092098/differentiated-and-anaplastic-thyroid-carcinoma-major-changes-in-the-american-joint-committee-on-cancer-eighth-edition-cancer-staging-manual
#6
REVIEW
Nancy D Perrier, James D Brierley, R Michael Tuttle
Answer questions and earn CME/CNE This is a review of the major changes in the American Joint Committee on Cancer staging manual, eighth edition, for differentiated and anaplastic thyroid carcinoma. All patients younger than 55 years have stage I disease unless they have distant metastases, in which case, their disease is stage II. In patients aged 55 years or older, the presence of distant metastases confers stage IVB, while cases without distant metastases are further categorized based on the presence/absence of gross extrathyroidal extension, tumor size, and lymph node status...
November 1, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29023627/falls-and-disability-among-female-cancer-survivors
#7
Lara C Pullen
No abstract text is available yet for this article.
October 10, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29028110/melanoma-staging-evidence-based-changes-in-the-american-joint-committee-on-cancer-eighth-edition-cancer-staging-manual
#8
Jeffrey E Gershenwald, Richard A Scolyer, Kenneth R Hess, Vernon K Sondak, Georgina V Long, Merrick I Ross, Alexander J Lazar, Mark B Faries, John M Kirkwood, Grant A McArthur, Lauren E Haydu, Alexander M M Eggermont, Keith T Flaherty, Charles M Balch, John F Thompson
Answer questions and earn CME/CNE To update the melanoma staging system of the American Joint Committee on Cancer (AJCC) a large database was assembled comprising >46,000 patients from 10 centers worldwide with stages I, II, and III melanoma diagnosed since 1998. Based on analyses of this new database, the existing seventh edition AJCC stage IV database, and contemporary clinical trial data, the AJCC Melanoma Expert Panel introduced several important changes to the Tumor, Nodes, Metastasis (TNM) classification and stage grouping criteria...
November 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29023645/higher-cigarette-pricing-encourages-older-smokers-to-quit
#9
Lara C Pullen
No abstract text is available yet for this article.
November 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28972651/breast-cancer-statistics-2017-racial-disparity-in-mortality-by-state
#10
Carol E DeSantis, Jiemin Ma, Ann Goding Sauer, Lisa A Newman, Ahmedin Jemal
In this article, the American Cancer Society provides an overview of female breast cancer statistics in the United States, including data on incidence, mortality, survival, and screening. Approximately 252,710 new cases of invasive breast cancer and 40,610 breast cancer deaths are expected to occur among US women in 2017. From 2005 to 2014, overall breast cancer incidence rates increased among Asian/Pacific Islander (1.7% per year), non-Hispanic black (NHB) (0.4% per year), and Hispanic (0.3% per year) women but were stable in non-Hispanic white (NHW) and American Indian/Alaska Native (AI/AN) women...
November 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28961314/key-issues-surrounding-the-health-impacts-of-electronic-nicotine-delivery-systems-ends-and-other-sources-of-nicotine
#11
REVIEW
Jeffrey Drope, Zachary Cahn, Rosemary Kennedy, Alex C Liber, Michal Stoklosa, Rosemarie Henson, Clifford E Douglas, Jacqui Drope
Answer questions and earn CME/CNE Over the last decade, the use of electronic nicotine delivery systems (ENDS), including the electronic cigarette or e-cigarette, has grown rapidly. More youth now use ENDS than any tobacco product. This extensive research review shows that there are scientifically sound, sometimes competing arguments about ENDS that are not immediately and/or completely resolvable. However, the preponderance of the scientific evidence to date suggests that current-generation ENDS products are demonstrably less harmful than combustible tobacco products such as conventional cigarettes in several key ways, including by generating far lower levels of carcinogens and other toxic compounds than combustible products or those that contain tobacco...
November 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28961310/treatment-of-renal-cell-carcinoma-current-status-and-future-directions
#12
REVIEW
Pedro C Barata, Brian I Rini
Answer questions and earn CME/CNE Over the past 12 years, medical treatment for renal cell carcinoma (RCC) has transitioned from a nonspecific immune approach (in the cytokine era), to targeted therapy against vascular endothelial growth factor (VEGF), and now to novel immunotherapy agents. Multiple agents-including molecules against vascular endothelial growth factor, platelet-derived growth factor, and related receptors; inhibitors of other targets, such as the mammalian target of rapamycin and the MET and AXL tyrosine-protein kinase receptors; and an immune-checkpoint inhibitor-have been approved based on significant activity in patients with advanced RCC...
November 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28881380/missed-therapeutic-and-prevention-opportunities-in-women-with-brca-mutated-epithelial-ovarian-cancer-and-their-families-due-to-low-referral-rates-for-genetic-counseling-and-brca-testing-a-review-of-the-literature
#13
REVIEW
Paul J Hoskins, Walter H Gotlieb
Answer questions and earn CME/CNE Fifteen percent of women with epithelial ovarian cancer have inherited mutations in the BRCA breast cancer susceptibility genes. Knowledge of her BRCA status has value both for the woman and for her family. A therapeutic benefit exists for the woman with cancer, because a new family of oral drugs, the poly ADP-ribose polymerase (PARP) inhibitors, has recently been approved, and these drugs have the greatest efficacy in women who carry the mutation. For her family, there is the potential to prevent ovarian cancer in those carrying the mutation by using risk-reducing surgery...
November 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28914965/reviewer-acknowledgment-2017
#14
(no author information available yet)
No abstract text is available yet for this article.
September 15, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28763097/obesity-and-adverse-breast-cancer-risk-and-outcome-mechanistic-insights-and-strategies-for-intervention
#15
REVIEW
Manuel Picon-Ruiz, Cynthia Morata-Tarifa, Janeiro J Valle-Goffin, Eitan R Friedman, Joyce M Slingerland
Answer questions and earn CME/CNE Recent decades have seen an unprecedented rise in obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than 1.9 billion adults were overweight (body mass index [BMI], 25-29.9 kg/m(2) ), and of these, over 600 million were obese (BMI ≥30 kg/m(2) ). Although the association between obesity and the risk of diabetes and coronary artery disease is widely known, the impact of obesity on cancer incidence, morbidity, and mortality is not fully appreciated...
September 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28753241/the-importance-of-immunization-in-cancer-prevention-treatment-and-survivorship
#16
REVIEW
Elizabeth M Ward, Christopher R Flowers, Ted Gansler, Saad B Omer, Robert A Bednarczyk
Answer questions and earn CME/CNE A measles outbreak originating in California during 2014 and 2015 called attention to the potential for infectious disease outbreaks related to underimmunized populations in the United States and the potential risk to pediatric patients with cancer attending school when such outbreaks occur. Compliance with vaccine recommendations is important for the prevention of hepatitis B-related and human papillomavirus-related cancers and for protecting immunocompromised patients with cancer, and these points are often overlooked, resulting in the continued occurrence of vaccine-preventable neoplastic and infectious diseases and complications...
September 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28738442/charting-the-future-of-cancer-health-disparities-research-a-position-statement-from-the-american-association-for-cancer-research-the-american-cancer-society-the-american-society-of-clinical-oncology-and-the-national-cancer-institute
#17
Blase N Polite, Lucile L Adams-Campbell, Otis W Brawley, Nina Bickell, John M Carethers, Christopher R Flowers, Margaret Foti, Scarlett Lin Gomez, Jennifer J Griggs, Christopher S Lathan, Christopher I Li, J Leonard Lichtenfeld, Worta McCaskill-Stevens, Electra D Paskett
No abstract text is available yet for this article.
September 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28731537/frailty-and-cancer-implications-for-oncology-surgery-medical-oncology-and-radiation-oncology
#18
REVIEW
Cecilia G Ethun, Mehmet A Bilen, Ashesh B Jani, Shishir K Maithel, Kenneth Ogan, Viraj A Master
Answer questions and earn CME/CNE The concept of frailty has become increasingly recognized as one of the most important issues in health care and health outcomes and is of particular importance in patients with cancer who are receiving treatment with surgery, chemotherapy, and radiotherapy. Because both cancer itself, as well as the therapies offered, can be significant additional stressors that challenge a patient's physiologic reserve, the incidence of frailty in older patients with cancer is especially high-it is estimated that over one-half of older patients with cancer have frailty or prefrailty...
September 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28697273/evidence-supports-the-use-of-multidisciplinary-team-meetings
#19
COMMENT
Lara C Pullen
No abstract text is available yet for this article.
September 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28697271/encouraging-long-term-outcomes-reported-in-patients-with-stage-i-non-small-cell-lung-cancer-treated-with-stereotactic-ablative-radiotherapy
#20
COMMENT
Mary Kay Barton
No abstract text is available yet for this article.
September 2017: CA: a Cancer Journal for Clinicians
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