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CA: a Cancer Journal for Clinicians

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https://www.readbyqxmd.com/read/29603147/timely-follow-up-of-positive-cancer-screening-results-a-systematic-review-and-recommendations-from-the-prospr-consortium
#1
REVIEW
Chyke A Doubeni, Nicole B Gabler, Cosette M Wheeler, Anne Marie McCarthy, Philip E Castle, Ethan A Halm, Mitchell D Schnall, Celette S Skinner, Anna N A Tosteson, Donald L Weaver, Anil Vachani, Shivan J Mehta, Katharine A Rendle, Stacey A Fedewa, Douglas A Corley, Katrina Armstrong
Timely follow-up for positive cancer screening results remains suboptimal, and the evidence base to inform decisions on optimizing the timeliness of diagnostic testing is unclear. This systematic review evaluated published studies regarding time to follow-up after a positive screening for breast, cervical, colorectal, and lung cancers. The quality of available evidence was very low or low across cancers, with potential attenuated or reversed associations from confounding by indication in most studies. Overall, evidence suggested that the risk for poorer cancer outcomes rises with longer wait times that vary within and across cancer types, which supports performing diagnostic testing as soon as feasible after the positive result, but evidence for specific time targets is limited...
March 30, 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29603144/pain-management-for-patients-with-cancer
#2
(no author information available yet)
No abstract text is available yet for this article.
March 30, 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29603142/optimal-pain-management-for-patients-with-cancer-in-the-modern-era
#3
REVIEW
Bethann M Scarborough, Cardinale B Smith
Pain is a common symptom among patients with cancer. Adequate pain assessment and management are critical to improve the quality of life and health outcomes in this population. In this review, the authors provide a framework for safely and effectively managing cancer-related pain by summarizing the evidence for the importance of controlling pain, the barriers to adequate pain management, strategies to assess and manage cancer-related pain, how to manage pain in patients at risk of substance use disorder, and considerations when managing pain in a survivorship population...
March 30, 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29574786/immune-checkpoint-inhibitors-are-superior-to-docetaxel-as-second-line-therapy-for-patients-with-non-small-cell-lung-carcinoma
#4
Mike Fillon
No abstract text is available yet for this article.
March 25, 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29574775/internet-interventions-help-patients-newly-diagnosed-with-cancer-improve-their-quality-of-life
#5
Ted Gansler
No abstract text is available yet for this article.
March 25, 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29573344/changes-in-inflammation-and-insulin-pathways-mediate-the-association-between-resistance-training-and-breast-cancer-survival
#6
Mike Fillon
No abstract text is available yet for this article.
March 24, 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29485237/recent-progress-in-lynch-syndrome-and-other-familial-colorectal-cancer-syndromes
#7
REVIEW
Patrick M Boland, Matthew B Yurgelun, C Richard Boland
The current understanding of familial colorectal cancer was limited to descriptions of affected pedigrees until the early 1990s. A series of landscape-altering discoveries revealed that there were distinct forms of familial cancer, and most were related to genes previously not known to be involved in human disease. This review largely focuses on advances in our understanding of Lynch syndrome because of the unique relationship of this disease to defective DNA mismatch repair and the clinical implications this has for diagnostics, prevention, and therapy...
February 27, 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29384589/who-s-still-smoking-disparities-in-adult-cigarette-smoking-prevalence-in-the-united-states
#8
Jeffrey Drope, Alex C Liber, Zachary Cahn, Michal Stoklosa, Rosemary Kennedy, Clifford E Douglas, Rosemarie Henson, Jacqui Drope
The continuing high prevalence of cigarette smoking among specific subpopulations, many of them vulnerable, is one of the most pressing challenges facing the tobacco control community. These populations include individuals in lower education and/or socioeconomic groups; from certain racial/ethnic groups; in the lesbian, gay, bisexual, and transgender community; with mental illness; and in the military, particularly among those in the lowest pay grades. Although traditional tobacco control measures are having positive health effects for most groups, the effects are not sufficient for others...
January 31, 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29377070/factors-influencing-risk-based-care-of-the-childhood-cancer-survivor-in-the-21st-century
#9
REVIEW
Stephanie B Dixon, Kari L Bjornard, Nicole M Alberts, Gregory T Armstrong, Tara M Brinkman, Wassim Chemaitilly, Matthew J Ehrhardt, Israel Fernandez-Pineda, Lisa M Force, Todd M Gibson, Daniel M Green, Carrie R Howell, Sue C Kaste, Anne C Kirchhoff, James L Klosky, Kevin R Krull, John T Lucas, Daniel A Mulrooney, Kirsten K Ness, Carmen L Wilson, Yutaka Yasui, Leslie L Robison, Melissa M Hudson
The population of adult survivors of childhood cancer continues to grow as survival rates improve. Although it is well established that these survivors experience various complications and comorbidities related to their malignancy and treatment, this risk is modified by many factors that are not directly linked to their cancer history. Research evaluating the influence of patient-specific demographic and genetic factors, premorbid and comorbid conditions, health behaviors, and aging has identified additional risk factors that influence cancer treatment-related toxicity and possible targets for intervention in this population...
March 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29338071/the-financial-burden-and-distress-of-patients-with-cancer-understanding-and-stepping-up-action-on-the-financial-toxicity-of-cancer-treatment
#10
REVIEW
Pricivel M Carrera, Hagop M Kantarjian, Victoria S Blinder
"Financial toxicity" has now become a familiar term used in the discussion of cancer drugs, and it is gaining traction in the literature given the high price of newer classes of therapies. However, as a phenomenon in the contemporary treatment and care of people with cancer, financial toxicity is not fully understood, with the discussion on mitigation mainly geared toward interventions at the health system level. Although important, health policy prescriptions take time before their intended results manifest, if they are implemented at all...
March 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29319885/patient-selection-in-major-upper-abdominal-surgery-for-cancer-in-octogenarians
#11
Lara C Pullen
No abstract text is available yet for this article.
March 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29319847/decision-making-in-breast-cancer-risk-reduction
#12
Lara C Pullen
No abstract text is available yet for this article.
March 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29194581/hodgkin-lymphoma-a-review-and-update-on-recent-progress
#13
REVIEW
Satish Shanbhag, Richard F Ambinder
Hodgkin lymphoma (HL) is a unique hematopoietic neoplasm characterized by cancerous Reed-Sternberg cells in an inflammatory background. Patients are commonly diagnosed with HL in their 20s and 30s, and they present with supradiaphragmatic lymphadenopathy, often with systemic B symptoms. Even in advanced-stage disease, HL is highly curable with combination chemotherapy, radiation, or combined-modality treatment. Although the same doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapeutic regimen has been the mainstay of therapy over the last 30 years, risk-adapted approaches have helped de-escalate therapy in low-risk patients while intensifying treatment for higher risk patients...
March 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29369334/the-incidental-thyroid-nodule
#14
REVIEW
Sarah B Fisher, Nancy D Perrier
Incidental thyroid nodules that are found on an imaging study performed for reasons other than thyroid pathology represent a common scenario encountered by health care providers. The initial workup for these nodules comprises a thorough history and physical examination, thyroid function tests, a dedicated thyroid ultrasound, and fine-needle aspiration of any suspicious lesions. Management ranges from observation and reassurance to surgical resection and depends on the cytologic diagnosis. In cases of cytologically indeterminate or discordant nodules, surgical excision (lobectomy) offers a definitive diagnosis, although molecular testing or a reasonable period of observation may be useful as less invasive adjuncts...
January 25, 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29313949/cancer-statistics-2018
#15
Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal
Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths that will occur in the United States and compiles the most recent data on cancer incidence, mortality, and survival. Incidence data, available through 2014, were collected by the Surveillance, Epidemiology, and End Results Program; the National Program of Cancer Registries; and the North American Association of Central Cancer Registries. Mortality data, available through 2015, were collected by the National Center for Health Statistics...
January 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29165798/weight-management-and-physical-activity-throughout-the-cancer-care-continuum
#16
REVIEW
Wendy Demark-Wahnefried, Kathryn H Schmitz, Catherine M Alfano, Jennifer R Bail, Pamela J Goodwin, Cynthia A Thomson, Don W Bradley, Kerry S Courneya, Christie A Befort, Crystal S Denlinger, Jennifer A Ligibel, William H Dietz, Melinda R Stolley, Melinda L Irwin, Marcas M Bamman, Caroline M Apovian, Bernardine M Pinto, Kathleen Y Wolin, Rachel M Ballard, Andrew J Dannenberg, Elizabeth G Eakin, Matt M Longjohn, Susan D Raffa, Lucile L Adams-Campbell, Joanne S Buzaglo, Sharyl J Nass, Greta M Massetti, Erin P Balogh, Elizabeth S Kraft, Anand K Parekh, Darshak M Sanghavi, G Stephen Morris, Karen Basen-Engquist
Mounting evidence suggests that weight management and physical activity (PA) improve overall health and well being, and reduce the risk of morbidity and mortality among cancer survivors. Although many opportunities exist to include weight management and PA in routine cancer care, several barriers remain. This review summarizes key topics addressed in a recent National Academies of Science, Engineering, and Medicine workshop entitled, "Incorporating Weight Management and Physical Activity Throughout the Cancer Care Continuum...
January 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29160902/proportion-and-number-of-cancer-cases-and-deaths-attributable-to-potentially-modifiable-risk-factors-in-the-united-states
#17
Farhad Islami, Ann Goding Sauer, Kimberly D Miller, Rebecca L Siegel, Stacey A Fedewa, Eric J Jacobs, Marjorie L McCullough, Alpa V Patel, Jiemin Ma, Isabelle Soerjomataram, W Dana Flanders, Otis W Brawley, Susan M Gapstur, Ahmedin Jemal
Contemporary information on the fraction of cancers that potentially could be prevented is useful for priority setting in cancer prevention and control. Herein, the authors estimate the proportion and number of invasive cancer cases and deaths, overall (excluding nonmelanoma skin cancers) and for 26 cancer types, in adults aged 30 years and older in the United States in 2014, that were attributable to major, potentially modifiable exposures (cigarette smoking; secondhand smoke; excess body weight; alcohol intake; consumption of red and processed meat; low consumption of fruits/vegetables, dietary fiber, and dietary calcium; physical inactivity; ultraviolet radiation; and 6 cancer-associated infections)...
January 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29155450/risk-of-ovarian-function-recovery-should-be-considered-when-switching-from-treatment-with-adjuvant-tamoxifen-to-aromatase-inhibitor-therapy-in-women-with-chemotherapy-induced-amenorrhea
#18
https://www.readbyqxmd.com/read/29155447/older-adults-may-not-consider-life-expectancy-an-important-factor-in-cancer-screening
#19
Clement Chung
No abstract text is available yet for this article.
January 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29092098/differentiated-and-anaplastic-thyroid-carcinoma-major-changes-in-the-american-joint-committee-on-cancer-eighth-edition-cancer-staging-manual
#20
REVIEW
Nancy D Perrier, James D Brierley, R Michael Tuttle
Answer questions and earn CME/CNE This is a review of the major changes in the American Joint Committee on Cancer staging manual, eighth edition, for differentiated and anaplastic thyroid carcinoma. All patients younger than 55 years have stage I disease unless they have distant metastases, in which case, their disease is stage II. In patients aged 55 years or older, the presence of distant metastases confers stage IVB, while cases without distant metastases are further categorized based on the presence/absence of gross extrathyroidal extension, tumor size, and lymph node status...
January 2018: CA: a Cancer Journal for Clinicians
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