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Brain Injury: [BI]

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https://www.readbyqxmd.com/read/28631942/a-systematic-review-of-factors-affecting-driving-and-public-transportation-among-youth-and-young-adults-with-acquired-brain-injury
#1
Sally Lindsay, Andrei Stoica
PURPOSE: Although many people with an acquired brain injury (ABI) encounter difficulties with executive functioning and memory which could negatively affect driving, few people are assessed for fitness to drive after injury. The purpose of this systematic review was to synthesize the literature on factors affecting driving and public transportation among youth and young adults with ABI, post injury. METHOD: Seven databases were systematically searched for articles from 1980 to 2016...
June 20, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28627942/diffusion-imaging-of-mild-traumatic-brain-injury-in-the-impact-accelerated-rodent-model-a-pilot-study
#2
Zora Kikinis, Marc Muehlmann, Ofer Pasternak, Sharon Peled, Praveen Kulkarni, Craig Ferris, Sylvain Bouix, Yogesh Rathi, Inga K Koerte, Steve Pieper, Alexander Yarmarkovich, Caryn L Porter, Bruce S Kristal, Martha E Shenton
PRIMARY OBJECTIVE: There is a need to understand pathologic processes of the brain following mild traumatic brain injury (mTBI). Previous studies report axonal injury and oedema in the first week after injury in a rodent model. This study aims to investigate the processes occurring 1 week after injury at the time of regeneration and degeneration using diffusion tensor imaging (DTI) in the impact acceleration rat mTBI model. RESEARCH DESIGN: Eighteen rats were subjected to impact acceleration injury, and three rats served as sham controls...
June 19, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28627941/detecting-social-cognitive-deficits-after-traumatic-brain-injury-an-ale-meta-analysis-of-fmri-studies
#3
Hui Xiao, Andre Jacobsen, Ziqian Chen, Yang Wang
PURPOSE: Traumatic brain injury (TBI) can result in significant social dysfunction, which is represented by impairment to social-cognitive abilities (i.e. social cognition, social attention/executive function and communication). This study is aimed to explore brain networks mediating the social dysfunction after TBI and its underlying mechanisms. METHODS: We performed a quantitative meta-analysis using the activation likelihood estimation (ALE) approach on functional magnetic resonance imaging (fMRI) studies of social-cognitive abilities following TBI...
June 19, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28627931/hyperacoustic-hypoacusis-a-new-pontine-syndrome-case-report
#4
Mohammad Hassan A Noureldine, Raghid Kikano, Naji Riachi, Rechdi Ahdab
We herein report a unique case of a lateral pontine demyelinating lesion presenting with unilateral sensorineural hearing loss and paradoxical ipsilateral hyperacusis. The association of unilateral hearing loss and ipsilateral hyperacusis is a rare manifestation of a central nervous system lesion. The paradoxical combination of these symptoms strongly suggests pontine dysfunction and prompts urgent neurological evaluation.
June 19, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28585898/circulating-extracellular-dna-levels-are-acutely-elevated-in-ischaemic-stroke-and-associated-with-innate-immune-system-activation
#5
Grant C O'Connell, Ashley B Petrone, Connie S Tennant, Noelle Lucke-Wold, Yasser Kabbani, Abdul R Tarabishy, Paul D Chantler, Taura L Barr
OBJECTIVE: The objective of this work was to assess the ability of peripheral blood cell-free DNA (cfDNA) levels to identify ischaemic stroke early in the acute phase of care, as well as to examine the relationship between peripheral blood cfDNA levels and stroke-induced innate immune system activation. METHODS: Upon emergency department admission, peripheral blood samples were obtained from 43 patients experiencing acute ischaemic stroke and 20 patients identified as stroke mimics...
June 6, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28585887/symptomatic-ptosis-cerebelli-after-suboccipital-craniectomy-in-a-patient-with-severe-brain-trauma
#6
Ana M Castaño-Leon, Santiago Cepeda, Igor Paredes, Pedro A Gómez, Luis Jiménez-Roldán, Alfonso Lagares, Angel Pérez-Núñez
PRIMARY OBJECTIVE: To report the first case of symptomatic cerebellar ptosis after a large suboccipital craniectomy in a patient with severe brain trauma and a review of the literature. PATIENT AND METHODS: A 36-year-old man suffered severe traumatic brain injury after a four-metre fall. He underwent a large suboccipital craniectomy because his computed tomography scan revealed a posterior fossa subdural haematoma and cerebellar swelling. Four weeks after admission, he developed communicating hydrocephalus, and a ventriculoperitoneal shunt was placed...
June 6, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28585883/dissimulation-strategies-on-standard-neuropsychological-tests-a-qualitative-investigation
#7
Stephanie M Jones
OBJECTIVE: Most previous studies in the area of malingering neuropsychological deficits have focused on the development and validation of measures to detect falsification of symptoms or suboptimal performance. The present study employs qualitative methods to investigate strategies employed by individuals attempting to feign cognitive impairment. This study aims to achieve a richer and more detailed understanding of the phenomenon of feigning. METHOD: Detailed semi-structured interviews were administered to 15 non-neurological individuals instructed to feign cognitive impairment on a standard neuropsychological test battery...
June 6, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28585880/service-needs-and-barriers-to-care-five-or-more-years-after-moderate-to-severe-tbi-among-veterans
#8
R Jay Schulz-Heik, John H Poole, Marie N Dahdah, Campbell Sullivan, Maheen M Adamson, Elaine S Date, Rose Salerno, Karen Schwab, Odette Harris
PRIMARY OBJECTIVE: The objective of this paper is to identify the most frequent service needs, factors associated with needs, and barriers to care among Veterans and service members five or more years after moderate to severe traumatic brain injury (TBI). RESEARCH DESIGN: Survey administered via telephone 5-16 years after injury (median eight years) and subsequent acute inpatient rehabilitation at a regional Veterans Affairs (VA) medical centre. METHODS AND PROCEDURES: Participants were 119 Veterans and military personnel, aged 23-70 (median 35), 90% male...
June 6, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28585861/alternative-measures-reveal-different-but-low-estimates-of-labour-market-attachment-after-severe-traumatic-brain-injury-a-nationwide-cohort-study
#9
Lene Odgaard, Søren Paaske Johnsen, Peter William Stubbs, Asger Roer Pedersen, Jørgen Feldbæk Nielsen
OBJECTIVE: To explore if the definition of labour market attachment (LMA) changes LMA proportions after severe traumatic brain injury (TBI). DESIGN: Cohort study with 5-year follow-up. PARTICIPANTS: Patients aged 18-64 years with severe TBI from 2004 to 2012 (n = 637) and matched controls (n = 2497). METHODS: LMA was defined in three ways. All definitions included patients working with no government benefits. Definition 2 included patients receiving unemployment benefits (LMA-unemployment benefits)...
June 6, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28534673/effects-of-preference-and-sensory-modality-on-behavioural-reaction-in-patients-with-disorders-of-consciousness
#10
L Heine, B Tillmann, M Hauet, A Juliat, A Dubois, S Laureys, M Kandel, J Plailly, J Luauté, F Perrin
BACKGROUND: Reliable evaluation of patients with unresponsive wakefulness syndrome (UWS) or in a minimally conscious state (MCS) remains a major challenge. It has been suggested that the expression of residual cerebral function could be improved by allowing patients to listen to their favourite music. However, the potential effect of music on behavioural responsiveness, as well as the effect of preferred stimuli in other sensory modalities (e.g. olfaction), remain poorly understood. OBJECTIVE: The aim of our study was to investigate the effect of sensory modality (auditory versus olfactory) and preference (preferred versus neutral) of the test stimuli on patients' subsequent performance on the Coma Recovery Scale-Revised (CRS-R)...
May 23, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28534652/a-review-of-the-evidence-of-zolpidem-efficacy-in-neurological-disability-after-brain-damage-due-to-stroke-trauma-and-hypoxia-a-justification-of-further-clinical-trials
#11
J A Sutton, R P Clauss
During 15 years, 23 clinical reports and 6 studies have demonstrated associations between sub-sedative doses of zolpidem and recoveries from brain damage due to strokes, trauma and hypoxia. Clinical findings include unexpected awakenings from vegetative states and regressions of stroke symptoms after dosing that disappear during elimination and reappear on repeat dosing. Initially single-photon emission computed tomography scans showed improved perfusion within, around and distant from infarctions. Then positron emission tomography scans and electroencephalography detected renewed metabolic and neuronal activity...
May 23, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28506130/fullerenol-nanoparticles-decrease-ischaemia-induced-brain-injury-and-oedema-through-inhibition-of-oxidative-damage-and-aquaporin-1-expression-in-ischaemic-stroke
#12
Shamsi Darabi, Mohammad Taghi Mohammadi
BACKGROUND: We examined the possible protective effects of fullerenol nanoparticles on brain injuries and oedema in experimental model of ischaemic stroke through inhibition of oxidative damage and aquaporin-1 (AQP-1) expression. METHODS: Experiment was done in three groups of rats (N = 66): sham, control ischaemia and ischaemic treatment. Ischaemia was induced by 90-minutes middle cerebral artery occlusion (MCAO) followed by 24 hours of reperfusion. Rats received a dose of 10 mg/kg of fullerenol 30 minutes before MCAO...
May 16, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28506094/a-preliminary-study-of-youth-sport-concussions-parents-health-literacy-and-knowledge-of-return-to-play-protocol-criteria
#13
Robert W Turner, Jeffery W Lucas, Lewis H Margolis, Brian N Corwell
PRIMARY OBJECTIVE: To preliminarily explore parents' health literacy and knowledge of youth sport league rules involving concussion education and training, and return-to-play protocols. RESEARCH DESIGN AND METHODS: This study was guided by the Knowledge, Attitude and Practice (KAP) model of health knowledge to examine parents' concussion literacy, and understanding of concussion education and training, and return-to-play protocols in youth sports. The mixed-method design involved 119 participants; that included in-person (n=8) and telephone (n=4) interviews, and web-based surveys administered through Mechanical Turk via Qualtrics (n=98)...
May 16, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28506087/differential-variations-of-autophagy-and-apoptosis-in-permanent-focal-cerebral-ischaemia-rat-model
#14
Pengyue Zhang, Liqiang Yang, Hongyun He, Yihao Deng
OBJECTIVE: Autophagy and apoptosis coexist in stroke, but the relationship between effects and complex is poorly understood. Herein, we investigated dynamic changes of autophagy and apoptosis at the penumbra in permanent cerebral ischaemia. METHODS: Sprague-Dawley rat models were prepared by middle cerebral artery occlusion. The autophagy and apoptosis were evaluated by Western blotting and immunofluorescence with LC3-II and cleaved caspase-3, respectively. The neurological deficit score and infarct volume were assessed...
May 16, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28506081/epidemiological-characteristics-of-chinese-paediatric-traumatic-brain-injury-inpatients
#15
Yunming Li, Fuqin Chen, Junran Zhang, Gang Li, Xiaoguang Yang, Qiang Lu, Xun Xia, Xinyan Zhang, Jun Qiu, Junpeng Zhang, Jihong Zhou, Yongqin Kuang, Jianwen Gu
PRIMARY OBJECTIVE: To investigate the epidemiological characteristics of paediatric inpatients with traumatic brain injury (TBI) in China. RESEARCH DESIGN: The Chinese Trauma Database (CTD), a nationwide register system based on hospital admission data, contains diagnosis and treatment information for trauma inpatients in over 200 military-managed public-service hospitals in China. Using the ICD-9 coding, the data for children with TBI aged 0-17 years between 2001 and 2007 were retrieved...
May 16, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28481672/prediction-of-behavioural-and-cognitive-deficits-in-patients-with-traumatic-brain-injury-at-an-acute-rehabilitation-setting
#16
E de Guise, J LeBlanc, M Feyz, J Lamoureux, S Greffou
OBJECTIVE: The goal of this study was to identify factors that would predict short-term neuropsychological outcome in patients with traumatic brain injury (TBI) hospitalized in an acute rehabilitation setting. METHODS: Data was collected in the context of an acute early rehabilitation setting of a trauma centre. A brief neuropsychological assessment was carried out for 348 patients within a month following their trauma. RESULTS: Length of post-traumatic amnesia (PTA) was the best predictor of behavioural, memory and executive function variables within a month post TBI...
May 8, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28481652/when-a-parent-suffers-abi-investigation-of-emotional-distress-in-children
#17
A Redolfi, G Bartolini, M Gugliotta, A Maietti, P Pietrapiana, S Sapienza, A D'Amato, A Mazzucchi
PRIMARY OBJECTIVE: To investigate the type of emotional and behavioural impact that having a parent with a severe acquired brain injury (ABI) has on children during the first period of adjustment. METHODS AND PROCEDURE: The study involved 25 couples in which one of the spouses was affected by ABI, and their 35 children (3-14 years). The children attended three sessions with a psychologist aimed at identifying their spontaneous playing and relational behaviour by means of a grid created on the basis of ICD-10 criteria...
May 8, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28481650/the-impact-of-compensation-on-late-mortality-after-traumatic-brain-injury-a-multi-centre-study
#18
Thomas Munro Gates, Ian James Baguley, Grahame Kenneth Simpson, Hannah Louise Holman Barden, Melissa Therese Nott
OBJECTIVES: To determine the impact of financial compensation on long-term mortality in adults with severe traumatic brain injury (TBI). DESIGN, SETTING AND PARTICIPANTS: An inception cohort of 2545 adults consecutively discharged from three metropolitan, post-acute inpatient rehabilitation services of the NSW Brain Injury Rehabilitation Programme from 1 July 1990 to 1 October 2007. MAIN OUTCOME MEASURE: Survival status at 1 October 2009. RESULTS: Compensation data were available for 1851 (73%) participants, with 826 (45%) receiving financial compensation...
May 8, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28481634/outpatient-follow-up-after-mild-traumatic-brain-injury-results-of-the-upfront-study
#19
M E de Koning, M E Scheenen, H J van der Horn, G Hageman, G Roks, T Yilmaz, J M Spikman, J van der Naalt
OBJECTIVE: To investigate outpatient follow-up after mild traumatic brain injury (mTBI) by various medical specialists, for both hospitalized and non-hospitalized patients, and to study guideline adherence regarding hospital admission. METHODS: Patients (n = 1151) with mTBI recruited from the emergency department received questionnaires 2 weeks (n = 879), 3 months (n = 780) and 6 months (n = 668) after injury comprising outpatient follow-up by various health care providers, and outcome defined by the Glasgow Outcome Scale Extended (GOS-E) after 6 months...
May 8, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28481625/focused-and-divided-attention-abilities-in-the-acute-phase-of-recovery-from-moderate-to-severe-traumatic-brain-injury
#20
Kayela Robertson, Maureen Schmitter-Edgecombe
PRIMARY OBJECTIVE: Impairments in attention following traumatic brain injury (TBI) can significantly impact recovery and rehabilitation effectiveness. This study investigated the multi-faceted construct of selective attention following TBI, highlighting the differences on visual nonsearch (focused attention) and search (divided attention) tasks. METHODS AND PROCEDURES: Participants were 30 individuals with moderate to severe TBI who were tested acutely (i.e. following emergence from PTA) and 30 age- and education-matched controls...
May 8, 2017: Brain Injury: [BI]
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