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Brain Injury: [BI]

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https://www.readbyqxmd.com/read/28534673/effects-of-preference-and-sensory-modality-on-behavioral-reaction-in-patients-with-disorders-of-consciousness
#1
L Heine, B Tillmann, M Hauet, A Juliat, A Dubois, S Laureys, M Kandel, J Plailly, J Luauté, F Perrin
BACKGROUND: Reliable evaluation of patients with unresponsive wakefulness syndrome (UWS) or in a minimally conscious state (MCS) remains a major challenge. It has been suggested that the expression of residual cerebral function could be improved by allowing patients to listen to their favourite music. However, the potential effect of music on behavioural responsiveness, as well as the effect of preferred stimuli in other sensory modalities (e.g. olfaction), remain poorly understood. OBJECTIVE: The aim of our study was to investigate the effect of sensory modality (auditory versus olfactory) and preference (preferred versus neutral) of the test stimuli on patients' subsequent performance on the Coma Recovery Scale-Revised (CRS-R)...
May 23, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28534652/a-review-of-the-evidence-of-zolpidem-efficacy-in-neurological-disability-after-brain-damage-due-to-stroke-trauma-and-hypoxia-a-justification-of-further-clinical-trials
#2
J A Sutton, R P Clauss
During 15 years, 23 clinical reports and 6 studies have demonstrated associations between sub-sedative doses of zolpidem and recoveries from brain damage due to strokes, trauma and hypoxia. Clinical findings include unexpected awakenings from vegetative states and regressions of stroke symptoms after dosing that disappear during elimination and reappear on repeat dosing. Initially single-photon emission computed tomography scans showed improved perfusion within, around and distant from infarctions. Then positron emission tomography scans and electroencephalography detected renewed metabolic and neuronal activity...
May 23, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28506130/fullerenol-nanoparticles-decrease-ischaemia-induced-brain-injury-and-oedema-through-inhibition-of-oxidative-damage-and-aquaporin-1-expression-in-ischaemic-stroke
#3
Shamsi Darabi, Mohammad Taghi Mohammadi
BACKGROUND: We examined the possible protective effects of fullerenol nanoparticles on brain injuries and oedema in experimental model of ischaemic stroke through inhibition of oxidative damage and aquaporin-1 (AQP-1) expression. METHODS: Experiment was done in three groups of rats (N = 66): sham, control ischaemia and ischaemic treatment. Ischaemia was induced by 90-minutes middle cerebral artery occlusion (MCAO) followed by 24 hours of reperfusion. Rats received a dose of 10 mg/kg of fullerenol 30 minutes before MCAO...
May 16, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28506094/a-preliminary-study-of-youth-sport-concussions-parents-health-literacy-and-knowledge-of-return-to-play-protocol-criteria
#4
Robert W Turner, Jeffery W Lucas, Lewis H Margolis, Brian N Corwell
PRIMARY OBJECTIVE: To preliminarily explore parents' health literacy and knowledge of youth sport league rules involving concussion education and training, and return-to-play protocols. RESEARCH DESIGN AND METHODS: This study was guided by the Knowledge, Attitude and Practice (KAP) model of health knowledge to examine parents' concussion literacy, and understanding of concussion education and training, and return-to-play protocols in youth sports. The mixed-method design involved 119 participants; that included in-person (n=8) and telephone (n=4) interviews, and web-based surveys administered through Mechanical Turk via Qualtrics (n=98)...
May 16, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28506087/differential-variations-of-autophagy-and-apoptosis-in-permanent-focal-cerebral-ischaemia-rat-model
#5
Pengyue Zhang, Liqiang Yang, Hongyun He, Yihao Deng
OBJECTIVE: Autophagy and apoptosis coexist in stroke, but the relationship between effects and complex is poorly understood. Herein, we investigated dynamic changes of autophagy and apoptosis at the penumbra in permanent cerebral ischaemia. METHODS: Sprague-Dawley rat models were prepared by middle cerebral artery occlusion. The autophagy and apoptosis were evaluated by Western blotting and immunofluorescence with LC3-II and cleaved caspase-3, respectively. The neurological deficit score and infarct volume were assessed...
May 16, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28506081/epidemiological-characteristics-of-chinese-paediatric-traumatic-brain-injury-inpatients
#6
Yunming Li, Fuqin Chen, Junran Zhang, Gang Li, Xiaoguang Yang, Qiang Lu, Xun Xia, Xinyan Zhang, Jun Qiu, Junpeng Zhang, Jihong Zhou, Yongqin Kuang, Jianwen Gu
PRIMARY OBJECTIVE: To investigate the epidemiological characteristics of paediatric inpatients with traumatic brain injury (TBI) in China. RESEARCH DESIGN: The Chinese Trauma Database (CTD), a nationwide register system based on hospital admission data, contains diagnosis and treatment information for trauma inpatients in over 200 military-managed public-service hospitals in China. Using the ICD-9 coding, the data for children with TBI aged 0-17 years between 2001 and 2007 were retrieved...
May 16, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28481672/prediction-of-behavioural-and-cognitive-deficits-in-patients-with-traumatic-brain-injury-at-an-acute-rehabilitation-setting
#7
E de Guise, J LeBlanc, M Feyz, J Lamoureux, S Greffou
OBJECTIVE: The goal of this study was to identify factors that would predict short-term neuropsychological outcome in patients with traumatic brain injury (TBI) hospitalized in an acute rehabilitation setting. METHODS: Data was collected in the context of an acute early rehabilitation setting of a trauma centre. A brief neuropsychological assessment was carried out for 348 patients within a month following their trauma. RESULTS: Length of post-traumatic amnesia (PTA) was the best predictor of behavioural, memory and executive function variables within a month post TBI...
May 8, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28481652/when-a-parent-suffers-abi-investigation-of-emotional-distress-in-children
#8
A Redolfi, G Bartolini, M Gugliotta, A Maietti, P Pietrapiana, S Sapienza, A D'Amato, A Mazzucchi
PRIMARY OBJECTIVE: To investigate the type of emotional and behavioural impact that having a parent with a severe acquired brain injury (ABI) has on children during the first period of adjustment. METHODS AND PROCEDURE: The study involved 25 couples in which one of the spouses was affected by ABI, and their 35 children (3-14 years). The children attended three sessions with a psychologist aimed at identifying their spontaneous playing and relational behaviour by means of a grid created on the basis of ICD-10 criteria...
May 8, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28481650/the-impact-of-compensation-on-late-mortality-after-traumatic-brain-injury-a-multi-centre-study
#9
Thomas Munro Gates, Ian James Baguley, Grahame Kenneth Simpson, Hannah Louise Holman Barden, Melissa Therese Nott
OBJECTIVES: To determine the impact of financial compensation on long-term mortality in adults with severe traumatic brain injury (TBI). DESIGN, SETTING AND PARTICIPANTS: An inception cohort of 2545 adults consecutively discharged from three metropolitan, post-acute inpatient rehabilitation services of the NSW Brain Injury Rehabilitation Programme from 1 July 1990 to 1 October 2007. MAIN OUTCOME MEASURE: Survival status at 1 October 2009. RESULTS: Compensation data were available for 1851 (73%) participants, with 826 (45%) receiving financial compensation...
May 8, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28481634/outpatient-follow-up-after-mild-traumatic-brain-injury-results-of-the-upfront-study
#10
M E de Koning, M E Scheenen, H J van der Horn, G Hageman, G Roks, T Yilmaz, J M Spikman, J van der Naalt
OBJECTIVE: To investigate outpatient follow-up after mild traumatic brain injury (mTBI) by various medical specialists, for both hospitalized and non-hospitalized patients, and to study guideline adherence regarding hospital admission. METHODS: Patients (n = 1151) with mTBI recruited from the emergency department received questionnaires 2 weeks (n = 879), 3 months (n = 780) and 6 months (n = 668) after injury comprising outpatient follow-up by various health care providers, and outcome defined by the Glasgow Outcome Scale Extended (GOS-E) after 6 months...
May 8, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28481625/focused-and-divided-attention-abilities-in-the-acute-phase-of-recovery-from-moderate-to-severe-traumatic-brain-injury
#11
Kayela Robertson, Maureen Schmitter-Edgecombe
PRIMARY OBJECTIVE: Impairments in attention following traumatic brain injury (TBI) can significantly impact recovery and rehabilitation effectiveness. This study investigated the multi-faceted construct of selective attention following TBI, highlighting the differences on visual nonsearch (focused attention) and search (divided attention) tasks. METHODS AND PROCEDURES: Participants were 30 individuals with moderate to severe TBI who were tested acutely (i.e. following emergence from PTA) and 30 age- and education-matched controls...
May 8, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28471267/technology-and-its-role-in-rehabilitation-for-people-with-cognitive-communication-disability-following-a-traumatic-brain-injury-tbi
#12
Melissa Brunner, Bronwyn Hemsley, Leanne Togher, Stuart Palmer
PURPOSE: To review the literature on communication technologies in rehabilitation for people with a traumatic brain injury (TBI), and: (a) determine its application to cognitive-communicative rehabilitation, and b) develop a model to guide communication technology use with people after TBI. METHOD: This integrative literature review of communication technology in TBI rehabilitation and cognitive-communication involved searching nine scientific databases and included 95 studies...
May 4, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28471243/utility-of-providing-a-concussion-definition-in-the-assessment-of-concussion-history-in-former-nfl-players
#13
Michael L Alosco, Johnny Jarnagin, Yorghos Tripodis, Brett Martin, Christine Chaisson, Christine M Baugh, Alcy Torres, Christopher J Nowinski, Robert C Cantu, Robert A Stern
OBJECTIVE: Former National Football League (NFL) players' working knowledge of concussion has not yet been evaluated, despite this population being a major clinical research target due to the association between repetitive head impacts (RHI) and long-term clinical impairments. This study examined former NFL players' understanding of the current concussion definition, and the association between number of concussions with clinical function. METHODS: 95 former NFL players (mean age = 55...
May 4, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28471238/clinician-perceptions-about-inpatient-occupational-therapy-groups-in-traumatic-brain-injury-rehabilitation
#14
Freyr Patterson, Jennifer Fleming, Emmah Doig
PRIMARY OBJECTIVE: The aim of the study was to explore the experiences and perceptions of clinicians about the benefits, challenges and processes of facilitating inpatient occupational therapy groups in traumatic brain injury (TBI) rehabilitation including peer-to-peer interactions and use of goals. DESIGN AND METHOD: A qualitative methodology, guided by a phenomenological approach was utilized with data collected from focus groups comprising 26 clinicians working in occupational therapy in three inpatient rehabilitation settings: brain injury, spinal injury and geriatric rehabilitation in order to identify aspects unique to brain injury rehabilitation...
May 4, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28440687/the-consequence-of-spatial-visual-processing-dysfunction-caused-by-traumatic-brain-injury-tbi
#15
William V Padula, Jose E Capo-Aponte, William V Padula, Eric L Singman, Jonathan Jenness
OBJECTIVE: A bi-modal visual processing model is supported by research to affect dysfunction following a traumatic brain injury (TBI). TBI causes dysfunction of visual processing affecting binocularity, spatial orientation, posture and balance. Research demonstrates that prescription of prisms influence the plasticity between spatial visual processing and motor-sensory systems improving visual processing and reducing symptoms following a TBI. RATIONALE: The rationale demonstrates that visual processing underlies the functional aspects of binocularity, balance and posture...
April 25, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28440675/near-infrared-spectroscopy-nirs-to-detect-traumatic-intracranial-haematoma-a-systematic-review-and-meta-analysis
#16
Robert J Brogan, Vassilios Kontojannis, Bhavin Garara, Hani J Marcus, Mark H Wilson
OBJECTIVES AND METHODS: Head injury is the most common trauma presentation to UK emergency departments, with around 1.2 million patients each year. The key management principal for this time critical illness remains early surgical intervention. With the development of handheld near-infrared spectroscopy (NIRS) devices, there is now the possibility of triaging and diagnosing these patients immediately, where computed tomography (CT) scanner is unavailable. NIRS has two related but distinct potential uses within clinical medicine...
April 25, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28421820/characteristics-associated-with-physical-activity-capacity-and-performance-in-children-and-adolescents-with-an-acquired-brain-injury
#17
Emmah Baque, Lee Barber, Leanne Sakzewski, Robert Ware, Roslyn N Boyd
AIM: To examine characteristics associated with physical activity capacity and performance in children with acquired brain injury (ABI). METHODS: 58 children (32 men; age 11 years 11 months ± 2 years 6 months; Gross motor function classification system [GMFCS] equivalent I = 29, II = 29) >12 months post ABI were recruited. Physical activity capacity measures included: (i) combined score of three 30-second repetition maximum functional strength exercises; (ii) timed up and go; (iii) 6-minute walk test and (iv) high-level mobility assessment tool (HiMAT)...
April 19, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28414250/longitudinal-changes-in-brain-morphology-from-4-weeks-to-12-months-after-mild-traumatic-brain-injury-associations-with-cognitive-functions-and-clinical-variables
#18
T Hellstrom, L T Westlye, S Sigurdardottir, C Brunborg, H L Soberg, Ø Holthe, A Server, M J Lund, O A Andreassen, N Andelic
OBJECTIVE: To investigate longitudinal changes in cortical and subcortical volumes in patients with mild traumatic brain injury (MTBI) and to evaluate whether such changes were associated with self-reported post-concussive symptoms, global functional outcomes and neuropsychological functioning. METHODS: This was a prospecitve, longitudinal cohort study of patients with complicated (i.e presence of intracranial abnormalities on the day of injury CT) and uncomplicated MTBI (i...
April 17, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28414249/psychological-distress-is-associated-with-altered-cognitive-functioning-in-family-caregivers-of-patients-with-disorders-of-consciousness
#19
P Moretta, O Masotta, E Crispino, G Castronovo, S Ruvolo, C Montalbano, V Loreto, L Trojano, A Estraneo
OBJECTIVES: To analyse the possible presence of reduced cognitive efficiency in family caregivers of patients with prolonged disorders of consciousness (DOC). SUBJECTS: The participants were 27 caregivers of 25 patients with DOC admitted to the severe brain injury units of the ICS Maugeri, Institutes of Telese Terme and Sciacca, Italy. METHODS: We examined cognitive functions such as short- and long-term memory, executive functions and attention by means of standardized tests...
April 17, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28414248/factors-that-predict-discharge-recommendations-following-paediatric-mild-traumatic-brain-injury
#20
Rachel M Roberts, Jessica Bunting, Mark Pertini
PRIMARY OBJECTIVE: To investigate factors that predict discharge recommendations for children and adolescents who present to an Australian paediatric Emergency Department (ED) following a mild traumatic brain injury (mTBI). RESEARCH DESIGN: Retrospective data base analysis. METHODS: The study retrospectively analysed an ED database to test the relationship between injury risk factors (symptoms, Glasgow Coma Scale, prior TBI, mechanism of injury and Computed Tomography scan), non-injury risk factors (sex, age, socio-economic status (SES)) and discharge recommendations of 2807 children and adolescents (0-18 years) who presented to a children's hospital ED over a three year period with mTBI...
April 17, 2017: Brain Injury: [BI]
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