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Brain Injury: [BI]

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https://www.readbyqxmd.com/read/29792533/efficacy-of-the-resilience-and-adjustment-intervention-after-traumatic-brain-injury-a-randomized-controlled-trial
#1
Jeffrey S Kreutzer, Jennifer H Marwitz, Adam P Sima, Ana Mills, Nancy H Hsu, Herman R Lukow
OBJECTIVE: Examine a psychoeducational and skill-building intervention's effectiveness for individuals after traumatic brain injury (TBI), using a two-arm, parallel, randomized, controlled trial with wait-listed control. METHODS: The Resilience and Adjustment Intervention (RAI) targets adjustment challenges and emphasizes education, skill-building and psychological support. Overall, 160 outpatients were randomly assigned to a treatment or wait-list control (WLC) group...
May 24, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29792528/dissociation-of-cerebrospinal-fluid-amyloid-%C3%AE-and-tau-levels-in-patients-with-prolonged-posttraumatic-disorders-of-consciousness
#2
Sergio Bagnato, Maria Andriolo, Cristina Boccagni, Antonino Sant'Angelo, Maria Enza D'Ippolito, Giuseppe Galardi
BACKGROUND: Traumatic brain injury (TBI) is a major risk factor for Alzheimer's disease (AD). Although the mechanisms that lead to AD after a TBI are unclear, we hypothesize that changes in amyloid-β (Aβ) metabolism and abnormal tau phosphorylation are reasonable candidates. OBJECTIVE: To investigate Aβ and tau dynamics in the chronic phase of TBI. METHODS: We evaluated Aβ1-42 , total tau (t-tau), and phosphorylated tau (p-tau) levels in the cerebrospinal fluid (CSF) of 15 patients who developed a prolonged disorder of consciousness after a severe TBI (mean time from TBI 271...
May 24, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29790790/the-effects-of-amantadine-on-traumatic-brain-injury-outcome-a-double-blind-randomized-controlled-clinical-trial
#3
Hossein Ghalaenovi, Arash Fattahi, Jalil Koohpayehzadeh, Mahmoud Khodadost, Neda Fatahi, Morteza Taheri, Alireza Azimi, Sadra Rohani, Hessam Rahatlou
INTRODUCTION: Amantadine, as a dopamine receptor agonist, may stimulate and help the recovery of the nervous system after traumatic brain injury (TBI). METHODS: We performed this study as a double-blind, randomized, controlled clinical trial with target population including all patients with TBI who scored nine or lower on the Glasgow Coma Scale (GCS), admitted to our hospital between January 2013 and April 2014. The protocol included administration of the drug (placebo or amantadine) for 6 weeks and patient evaluation using the GCS and FOUR score on the first, third and seventh days after the drug was started...
May 23, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29775093/introduction-to-tbi-model-systems-2012-2017-special-section
#4
Tamara Bushnik
No abstract text is available yet for this article.
May 18, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29775090/evaluation-of-management-and-guideline-adherence-in-children-with-mild-traumatic-brain-injury
#5
Merel C Broers, Jikke-Mien F Niermeijer, Irene A W Kotsopoulos, Hester F Lingsma, Jos F M Bruinenberg, Coriene E Catsman-Berrevoets
AIM: To evaluate the management and guideline adherence in children with mild traumatic brain injury (MTBI) in emergency departments (ED) in the Netherlands. METHODS: A multicentre cohort study was conducted, including children younger than 18 years with MTBI who presented within 24 hours after trauma in the ED of hospitals in the southwest region of the Netherlands, in 2014. Primary outcome measures for management were percentages of performed computed tomography (CT) scans and hospital admissions...
May 18, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29764207/practical-psychology-in-medical-rehabilitation
#6
Alasdair FitzGerald
No abstract text is available yet for this article.
May 15, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29757682/a-scoping-review-of-the-nature-and-outcomes-of-extended-rehabilitation-programmes-after-very-severe-brain-injury
#7
Lucy Knox, Jacinta M Douglas
PRIMARY OBJECTIVE: Many adults with very severe acquired brain injury (ABI) do not receive adequate rehabilitation, limiting their recovery and leading to admission to inappropriate living environments. The aim of this scoping review was to map the existing literature relating to the nature and outcomes of rehabilitation programmes for adults experiencing prolonged recovery after very severe ABI. DESIGN: A comprehensive scoping of the literature was undertaken, including systematic searching of databases, grey literature, and hand searching...
May 14, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29741969/frequency-and-prognostic-factors-of-olfactory-dysfunction-after-traumatic-brain-injury
#8
Mette Bratt, Toril Skandsen, Thomas Hummel, Kent G Moen, Anne Vik, Ståle Nordgård, Anne-S Helvik
OBJECTIVE: To assess the frequency and factors associated with posttraumatic olfactory dysfunction, including anosmia, in a follow-up of patients with moderate and severe traumatic brain injury (TBI). METHODS: The setting was a cross-sectional study of patients that were consecutively included in the Trondheim TBI database, comprising injury-related variables. Eligible participants 18-65 years were contacted 9-104 months post trauma and asked olfactory-related questions...
May 9, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29738278/functional-outcomes-following-post-acute-rehabilitation-for-moderate-to-severe-traumatic-brain-injury
#9
Amy M Rosenbaum, Wayne A Gordon, Antigone Joannou, Brady A Berman
OBJECTIVE: The objective of this study was to examine the benefits of long-term inpatient rehabilitation for individuals with moderate-to-severe traumatic brain injuries (TBIs). METHODS: Retrospective database review of 67 individuals with moderate-to-severe TBI admitted to a specialised inpatient TBI program. Outcome measures are as follows: (1) functional independence measure + functional assessment measure (FIM+FAM; admission, discharge, change scores); (2) discharge designation (community vs...
May 8, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29738277/methylphenidate-mediated-motor-control-network-enhancement-in-patients-with-traumatic-brain-injury
#10
Charlie L Dorer, Anne E Manktelow, Judith Allanson, Barbara J Sahakian, John D Pickard, Andrew Bateman, David K Menon, Emmanuel A Stamatakis
PRIMARY OBJECTIVE: To investigate functional improvement late (>6 months) after traumatic brain injury (TBI). To this end, we conducted a double-blind, placebo-controlled experimental medicine study to test the hypothesis that a widely used cognitive enhancer would benefit patients with TBI. RESEARCH DESIGN: We focused on motor control function using a sequential finger opposition fMRI paradigm in both patients and age-matched controls. METHODS AND PROCEDURES: Patients' fMRI and DTI scans were obtained after randomised administration of methylphenidate or placebo...
May 8, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29738275/psychiatric-diagnoses-of-children-affected-by-their-parents-traumatic-brain-injury-the-1987-finnish-birth-cohort-study
#11
Lotta Kinnunen, Mika Niemelä, Helinä Hakko, Jouko Miettunen, Marko Merikukka, Vesa Karttunen, Tiina Ristikari, Mika Gissler, Sami Räsänen
OBJECTIVE: To investigate whether parental TBI increases the overall risk for psychiatric disorders and the risk for specific psychiatric diagnoses in the children affected by parental TBI. METHODS: The 1987 Finnish Birth Cohort (n = 59 476) were followed up through national registers from birth to the end of 2008. The diagnoses of cohort members and their parents were obtained from the Care Register of Health Care, provided by the National Institute of Health and Welfare...
May 8, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29738269/psychological-and-behavioural-difficulties-following-severe-tbi-in-adolescence-a-comparison-with-a-sample-of-peers-with-brain-lesions-of-other-origin-and-with-a-control-group
#12
Valentina Pastore, Susanna Galbiati, Monica Recla, Katia Colombo, Elena Beretta, Sandra Strazzer
OBJECTIVE: To describe behavioural and adjustment problems in a group of 57 adolescents with severe traumatic brain injury (TBI) and compare them with a clinical group of peers with brain lesions of other origin (N = 33) and a control group of healthy adolescents (N = 48). METHODS: All subjects received an age-appropriate assessment, including the child behaviour checklist (CBCL) 4/18, the strengths and difficulties questionnaire (SDQ) and the vineland adaptive behaviour scales (VABS)...
May 8, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29737870/the-effect-of-donepezil-on-the-cognitive-ability-early-in-the-course-of-recovery-from-traumatic-brain-injury
#13
Kelsey A Campbell, Richard E Kennedy, Robert C Brunner, Sean D Hollis, Ross A Lumsden, Thomas A Novack
OBJECTIVE: To investigate the effect of donepezil on cognitive ability in patients who have sustained a traumatic brain injury (TBI). We hypothesized that donepezil, an acetylcholinesterase inhibitor, would enhance cognitive recovery beyond that of usual care in an acute rehabilitation facility. METHODS: This retrospective, longitudinal analysis included 55 patients who were non-randomly prescribed donepezil during acute care and compared them to 74 patients who received usual rehabilitation treatment...
May 8, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29718729/financial-hardship-after-traumatic-brain-injury-a-brief-scale-for-family-caregivers
#14
Scott A Sabella, Joshua H Andrzejewski, Alexandrea Wallgren
OBJECTIVE: Financial hardship is frequently posited as a significant factor influencing family health and adjustment after brain injury, though traditional methods of measurement have shown limited usefulness. The purpose of this study was to adapt and test the utility of a brief scale of financial hardship (BSFH-BI) for use with family caregivers after TBI. METHODS: The researchers constructed the BSFH-BI using financial well-being items adapted from three survey instruments...
May 2, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29718728/extra-practice-outside-therapy-sessions-to-maximize-training-opportunity-during-inpatient-rehabilitation-after-traumatic-brain-injury
#15
Joan Leung, Sarah Fereday, Bridget Sticpewich, Joe Hanna
OBJECTIVE: To determine if extra practice outside therapy sessions can be conducted for patients with traumatic brain injury and identify factors that influence their participation. METHODS: A purpose-designed survey was conducted on consecutive eligible patients with traumatic brain injury and their relatives on discharge from inpatient rehabilitation. RESULTS: In total, 68 of the 69 of patients who took part in the survey reported that they participated in extra practice outside therapy sessions...
May 2, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29718712/therapy-influences-goal-attainment-following-botulinum-neurotoxin-injection-for-focal-spasticity-in-adults-with-neurological-conditions
#16
Elizabeth Jane Moore, John Olver, Adam Leigh Bryant, Dean Philip McKenzie, Gavin Williams
OBJECTIVE: To determine whether therapy influenced goal attainment following botulinum toxin (BoNT-A) injection for focal spasticity in adults with neurological conditions. METHODS: A prospective observational cohort study conducted in a large metropolitan spasticity clinic on adults with focal spasticity of any origin. Participants were provided with a therapy programme, designed to maximise therapeutic outcome. The primary outcome measure was Goal Attainment Scaling...
May 2, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29708447/prevalence-and-predictors-of-tobacco-smoking-in-veterans-and-service-members-following-traumatic-brain-injury-rehabilitation-a-va-tbims-study
#17
Marc A Silva, Heather G Belanger, Kristen Dams-O'Connor, Xinyu Tang, Tamara McKenzie-Hartman, Risa Nakase-Richardson
OBJECTIVE: To identify prevalence and predictors of tobacco smoking among veterans and military service members (V/SM) with traumatic brain injury (TBI) admitted for rehabilitation. METHODS: Participants were drawn from the VA TBI Model Systems multicentre longitudinal research study. Tobacco smoking was assessed both preinjury and at 1- or 2-year post-TBI follow-up for 336 participants. RESULTS: Smoking prevalence was 32% preinjury and 28% at follow-up...
April 30, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29708442/psychological-well-being-in-individuals-living-in-the-community-with-traumatic-brain-injury
#18
Lisa Payne, Lenore Hawley, Jessica M Ketchum, Angela Philippus, C B Eagye, Clare Morey, Don Gerber, Cynthia Harrison-Felix, Ed Diener
BACKGROUND: Well-being and quality of life issues remain a long-term problem for many individuals with traumatic brain injury (TBI). Meaningful activity is key to developing life satisfaction and a sense of contribution to society, yet individuals with TBI are often unable to return to competitive employment. OBJECTIVE: To describe the self-reported psychological well-being of a cohort of unemployed individuals living in the community at least 1 year post TBI with low life satisfaction...
April 30, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29708438/outcomes-of-protocolised-analgesia-and-sedation-in-a-neurocritical-care-unit
#19
Leana Mahmoud, Andrew R Zullo, Bradford B Thompson, Linda C Wendell
OBJECTIVES: Providing analgesia and sedation while allowing for neurological assessment is important in the neurocritical care unit (NCCU), yet data are limited about the effects of protocolised analgesia and sedation. We developed an analgesia-based sedation protocol and evaluated its effect on medication utilisation and costs in the NCCU. METHODS: We conducted a retrospective cohort study of patients who are mechanically ventilated and admitted to a 12-bed NCCU over four years...
April 30, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29701515/intracranial-pressure-changes-after-mild-traumatic-brain-injury-a-systematic-review
#20
Mohammad Nadir Haider, John J Leddy, Andrea L Hinds, Nell Aronoff, Diane Rein, David Poulsen, Barry S Willer
OBJECTIVE: Intracranial pressure (ICP) after mild traumatic brain injury (mTBI) is poorly studied due to lack of sensitive non-invasive methods. The purpose of this review was to summarize the existing knowledge of changes in ICP after mTBI. Literature selection: PubMed, Embase, CINAHL, and Scopus were searched by three reviewers independently up to December 2016. INCLUSION CRITERIA: animal and human studies measuring ICP and brain oedema after an mTBI. EXCLUSION CRITERIA: moderate and severe forms of traumatic brain injury, repeat samples, and studies that measured ICP at the time of impact but not after...
April 27, 2018: Brain Injury: [BI]
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