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Brain Injury: [BI]

Tricia S Williams, Kyla P McDonald, Samantha D Roberts, Robyn Westmacott, Sara Ahola Kohut, Nomazulu Dlamini, Steven P Miller
PRIMARY OBJECTIVE: This study aimed to create a specific questionnaire (Parent Experiences Questionnaire) about early experiences, service involvement, and needs of children and parents following neonatal brain injury that could be used to inform clinical care and needed interventions. RESEARCH DESIGN AND METHODS: A mixed-method design was utilized, engaging in both qualitative and quantitative methods across three phases. Phase 1 employed participatory design involving 12 parent and clinician participants in semi-structured interviews to address main topics, item importance, and overall impressions of the questionnaire...
July 17, 2018: Brain Injury: [BI]
Duncan R Babbage, Barbra Zupan, Dawn Neumann, Barry Willer
OBJECTIVE: To examine sex differences in the effectiveness of a Stories intervention for teaching affect recognition in people with a traumatic brain injury (TBI). SETTING: Post-acute rehabilitation facilities. PARTICIPANTS: 203 participants (53 women and 150 men) with moderate to severe TBI were screened. 71 were eligible and randomized to one of three treatment conditions: two affect recognition conditions and an active control (cognition)...
July 17, 2018: Brain Injury: [BI]
Robert A Fieo, Hannah Silverman, Deirdre O'Shea, Masood Manoochehri, Jordan Grafman, Edward D Huey
OBJECTIVE: To develop a validated, caregiver-based measurement scale to assess sexual changes across several domains in a sample of 86 patients with penetrating traumatic brain injury (TBI) and 65 patients with neurodegeneration due to frontotemporal dementia and corticobasal syndrome. METHODS: A new measure, the Sexual Symptoms in Neurological Illness and Injury Questionnaire (SNIQ), was constructed. Dimensionality, monotonicity, item discrimination power, and scalability were evaluated using nonparametric Mokken item response theory (IRT) methodology...
July 16, 2018: Brain Injury: [BI]
David X Cifu, Rick Williams, Sidney R Hinds, Amma A Agyemang
No abstract text is available yet for this article.
July 16, 2018: Brain Injury: [BI]
Anna Tölli, Charlotte Höybye, Bo-Michael Bellander, Fredrik Johansson, Jörgen Borg
OBJECTIVES: To compare the effect of time on cognitive impairments after Subarachnoid Haemorrhage and Traumatic Brain Injury and explore associations with baseline variables and global function. METHODS: Patients with a Glasgow Coma Scale score of 3-13, were assessed at 3, 6 and 12 months post injury by use of BNIS for cognitive impairment, RLAS-R to categorise cognitive and behavioural function, Barthel Index to assess performance of daily living, HADS to screen for depression and anxiety, and EuroQoL-5D, LiSat-11 and Glasgow Outcome Scale Extended to assess global function...
July 16, 2018: Brain Injury: [BI]
Kagari Abiko, Tohru Shiga, Chietsugu Katoh, Kenji Hirata, Yuji Kuge, Kentaro Kobayashi, Satoshi Ikeda, Katsunori Ikoma
OBJECTIVE: Cerebral metabolism may play a significant role in neurobehavioural disability following traumatic brain injury (TBI). In this study, we examined the relationship between intelligence quotient (IQ) and the cerebral metabolic rate of oxygen (CMRO2 ) in the lateral prefrontal cortex, which was measured by 15 O-labelled gas positron emission tomography (PET), in patients with TBI. MATERIALS AND METHODS: The subjects were 12 patients (eight males and four females) who suffered from neurobehavioural disability following TBI...
July 16, 2018: Brain Injury: [BI]
Amber L Dougherty, Andrew J MacGregor, Erik Viirre, Mary C Clouser, Peggy P Han, Kimberly H Quinn, Michael R Galarneau
PRIMARY OBJECTIVE: To examine the relationship between hearing protection and non-impact, blast-induced concussion in US military personnel. RESEARCH DESIGN: Retrospective cohort study. METHODS AND PROCEDURES: A total of 501 US service members from the Expeditionary Medical Encounter Database with hearing protection status reported either 'worn' or 'not worn' were eligible for analysis. Clinical records were reviewed for concussion diagnoses...
July 12, 2018: Brain Injury: [BI]
Melissa L Mehalick, Amanda C Glueck
In this review, we discuss the comorbidity of traumatic brain injury (TBI) and pain among civilians and military members, the common causes of pain resulting from TBI, and offer insight about the therapeutic management of TBI symptoms and pain. Traumatic brain injury (TBI) is a debilitating health problem and one of the most common post-TBI symptoms is pain, which can contribute to psychological issues such as Post-traumatic stress disorder (PTSD) and depression. Headache pain appears to be the most common type of pain that results from TBI, yet pain can also be more widespread...
July 11, 2018: Brain Injury: [BI]
Kevin Sickinger, William C Walker, Amma A Agyemang, David X Cifu, Tiffany L Lewis, William Carne
PRIMARY OBJECTIVE: The primary objective of the study is to identify and delineate effective recruitment practises in a large, multi-site, longitudinal, observational study employing both military service members and Veterans. SETTING: Four Chronic Effects of Neurotrauma Consortium sites. DESIGN: A descriptive study. RESULTS: Overall and cohort-specific recruitment increased with the addition of focused recruitment strategies and a military/Veteran-centric recruitment director...
July 9, 2018: Brain Injury: [BI]
Shawn Hirsch, Heather G Belanger, Harvey Levin, Barry S Eggleston, Elisabeth A Wilde, Scott D McDonald, Timothy W Brearly, David F Tate
OBJECTIVE: The goal of the Chronic Effects of Neurotrauma Consortium (CENC) study is to explore the effects of concussions among Service Members and Veterans. A factor model was fit to selected neuropsychological measures to identify potentially useful relationships between assessments collected on CENC-enrolled participants. METHOD: 492 post-9/11 participants with combat exposure were enrolled across four VA study sites. Participants completed assessments including concussion history, neurocognitive functioning, and self-report questionnaires...
July 9, 2018: Brain Injury: [BI]
Sarah L Martindale, Jared A Rowland, Robert D Shura, Katherine H Taber
PRIMARY OBJECTIVE: The purpose of this study was to evaluate preliminary data on longitudinal changes in psychiatric, neurobehavioural, and neuroimaging findings in Iraq and Afghanistan combat veterans following blast exposure. RESEARCH DESIGN: Longitudinal observational analysis. METHODS AND PROCEDURES: Participants were invited to participate in two research projects approximately 7 years apart. For each project, veterans completed the Structured Clinical Interview for DSM-IV Disorders and/or the Clinician-Administered PTSD Scale, Neurobehavioral Symptom Inventory, and magnetic resonance imaging (MRI)...
July 9, 2018: Brain Injury: [BI]
Kelly M Jones, Nicola J Starkey, Alice Theadom, Alina Gheorghe, Dawn Willix-Payne, Philip Prah, Valery L Feigin
BACKGROUND: Mild traumatic brain injury (mTBI) in children is most commonly associated with parent-reported child behaviour problems. The extent to which parent and child ratings align is unknown. OBJECTIVES: To examine differences in child behaviour and patterns of recovery over the first 12 months following mTBI based on parent and child self-report. METHODS: Ninety-nine children (8-15 years) with mTBI and one of their parents completed the Behavioural Assessment Scale for Children - version 2 to assess child hyperactivity, anxiety and depression at baseline, 1, 6 and 12 months post-injury...
July 9, 2018: Brain Injury: [BI]
Sarah K Schellinger, Benjamin Munson, Mary R T Kennedy
AIM: Existing research suggests that the public demonstrates inadequate knowledge about traumatic brain injury (TBI), indicating a need for public education initiatives; however, limited research exists on the effectiveness of these initiatives. The purposes of this study were to (1) identify whether any demographic/personal variables (e.g. gender, age, experience with TBI) predicted TBI knowledge and (2) determine whether presenting an educational video to members of the general public would improve knowledge about TBI...
July 9, 2018: Brain Injury: [BI]
Ying Jiang, Yun-Kun Wang, Xiao-Lei Shi, Shen-Hao Wang, Yi-Ming Li, Jun-Yu Wang, Dan-Feng Zhang, Chao Ma, Ming-Kun Yu, Li-Jun Hou
OBJECTIVE: Delayed neurological deficit was often observed in patients underwent craniectomy, which could be improved by cranioplasty. Little is known about hemodynamic improvement before and after cranioplasty. METHODS: Cerebral blood perfusion, tympanic membrane temperature (TMT), neuropsychological and cognitive function were assessed in eleven craniectomy patients before and after cranioplasty. RESULTS: Before cranioplasty, the cerebral blood volume (CBV) on the decompressed side was significantly lower than that of the contralateral side...
July 9, 2018: Brain Injury: [BI]
Nicholas D Davenport, James T Gullickson, Scott F Grey, Shawn Hirsch, Scott R Sponheim
PRIMARY OBJECTIVE: To investigate differences in longitudinal trajectories of ventricle-brain ratio (VBR), a general measure of brain atrophy, between Veterans with and without history of mild traumatic brain injury (mTBI). RESEARCH DESIGN: Structural magnetic resonance imaging (MRI) was used to calculate VBR in 70 Veterans with a history of mTBI and 34 Veterans without such history at two time points approximately 3 and 8 years after a combat deployment. MAIN OUTCOMES AND RESULTS: Both groups demonstrated a quadratic relationship between VBR and age that is consistent with normal developmental trajectories...
July 9, 2018: Brain Injury: [BI]
Jerome Iruthayarajah, Fatimah Alibrahim, Swati Mehta, Shannon Janzen, Amanda McIntyre, Robert Teasell
BACKGROUND: Aggression is common after an acquired brain injury (ABI). Cognitive behavioural therapy (CBT) is a form of psychotherapy, in which therapists help patients to identify their maladaptive behaviours. OBJECTIVE: The objective of this systematic review and meta-analysis was to evaluate the effectiveness of CBT interventions in treating aggression in an ABI population. METHODS: A systematic literature search was conducted using: PubMed/MEDLINE, CINAHL, EMBASE and PsycINFO from database inception to August 2016...
July 9, 2018: Brain Injury: [BI]
Daniel Bertenthal, Kristine Yaffe, Deborah E Barnes, Amy L Byers, Carolyn J Gibson, Karen H Seal
OBJECTIVES: Opioid therapy is contraindicated in patients with traumatic brain injury (TBI) with neuropsychological impairment, yet guidelines do not consistently predict practice. We evaluated independent risk for initiation of opioid therapy among combat veterans with chronic pain diagnoses and persistent postconcussive symptoms. METHODS: We assembled a retrospective cohort of 53 124 Iraq and Afghanistan veterans in Veterans Affairs (VA) healthcare between October 2007 and March 2015 who received chronic pain diagnoses, completed a Comprehensive TBI Evaluation (CTBIE) and had not received opioid therapy in the prior year...
July 9, 2018: Brain Injury: [BI]
Juliet K Haarbauer-Krupa, R Dawn Comstock, Michael Lionbarger, Shawn Hirsch, Andrew Kavee, Brooks Lowe
OBJECTIVES: To describe concussion rates in high school athletes and involvement of healthcare professionals in concussion diagnosis, management and compliance with return to play (RTP) guidelines. METHODS: Data were analysed from injury reports in the National High School Sports-Related Injury Surveillance System between 2009/2010 and 2012/2013 to identify student athletes with concussion and determine compliance with RTP guidelines. Compliance with RTP guidelines was examined using logistic regression, adjusting for sport and injury-related variables...
June 28, 2018: Brain Injury: [BI]
David E Ross, John Seabaugh, Leah Cooper, Jan Seabaugh
This report describes the case of a 58-year-old man with moderate traumatic brain injury (TBI) and pre-accident brain disorders who had multiple persistent neuropsychiatric symptoms. NeuroQuant® 2.0 and NeuroGage® 2.0 MRI brain volume analyses were used during the chronic stage of injury (> 1 year after injury) to help understand the effects of the TBI on his brain volume. NeuroQuant® showed widespread cross-sectional atrophy, especially in the frontal and temporal lobes, consistent with encephalomalacia seen on the MRIs...
June 28, 2018: Brain Injury: [BI]
Benoit Mouzon, Nicole Saltiel, Scott Ferguson, Joseph Ojo, Carlyn Lungmus, Cillian Lynch, Moustafa Algamal, Alexander Morin, Benjamin Carper, Gayle Bieler, Elliott J Mufson, William Stewart, Michael Mullan, Fiona Crawford
OBJECTIVES: We hypothesized that polypathology is more severe in older than younger mice during the acute phase following repetitive mild traumatic brain injury (r-mTBI). METHODS: Young and aged male and female mice transgenic for human tau (hTau) were exposed to r-mTBI or a sham procedure. Twenty-four hours post-last injury, mouse brain tissue was immunostained for alterations in astrogliosis, microgliosis, tau pathology, and axonal injury. RESULTS: Quantitative analysis revealed a greater percent distribution of glial fibrillary acid protein and Iba-1 reactivity in the brains of all mice exposed to r-mTBI compared to sham controls...
June 21, 2018: Brain Injury: [BI]
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