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British Journal of Surgery

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https://www.readbyqxmd.com/read/28444964/randomized-clinical-trial-of-landiolol-hydrochloride-for-the-prevention-of-atrial-fibrillation-and-postoperative-complications-after-oesophagectomy-for-cancer
#1
T Ojima, M Nakamori, M Nakamura, M Katsuda, K Hayata, T Kato, J Kitadani, H Tabata, A Takeuchi, H Yamaue
BACKGROUND: Atrial fibrillation is common after oesophageal surgery. The aim of this study was to evaluate whether landiolol hydrochloride was effective and safe in the prevention of atrial fibrillation after oesophagectomy, and to see whether a reduction in incidence of atrial fibrillation would reduce other postoperative complications. METHODS: This single-centre study enrolled patients scheduled for transthoracic oesophagectomy in a randomized, double-blind, placebo-controlled trial between March 2013 and January 2016...
April 26, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28436602/accuracy-of-circulating-histones-in-predicting-persistent-organ-failure-and-mortality-in-patients-with-acute-pancreatitis
#2
T Liu, W Huang, P Szatmary, S T Abrams, Y Alhamdi, Z Lin, W Greenhalf, G Wang, R Sutton, C H Toh
BACKGROUND: Early prediction of acute pancreatitis severity remains a challenge. Circulating levels of histones are raised early in mouse models and correlate with disease severity. It was hypothesized that circulating histones predict persistent organ failure in patients with acute pancreatitis. METHODS: Consecutive patients with acute pancreatitis fulfilling inclusion criteria admitted to Royal Liverpool University Hospital were enrolled prospectively between June 2010 and March 2014...
April 24, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28425560/impact-of-simulated-three-dimensional-perception-on-precision-of-depth-judgements-technical-performance-and-perceived-workload-in-laparoscopy
#3
S Sakata, P M Grove, A Hill, M O Watson, A R L Stevenson
BACKGROUND: This study compared precision of depth judgements, technical performance and workload using two-dimensional (2D) and three-dimensional (3D) laparoscopic displays across different viewing distances. It also compared the accuracy of 3D displays with natural viewing, along with the relationship between stereoacuity and 3D laparoscopic performance. METHODS: A counterbalanced within-subjects design with random assignment to testing sequences was used. The system could display 2D or 3D images with the same set-up...
April 20, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28401542/quality-of-life-after-mastectomy-with-or-without-immediate-breast-reconstruction
#4
J Dauplat, F Kwiatkowski, P Rouanet, E Delay, K Clough, J L Verhaeghe, I Raoust, G Houvenaeghel, P Lemasurier, E Thivat, C Pomel
BACKGROUND: Mastectomy with immediate breast reconstruction (IBR) is a surgical strategy in breast cancer when breast-conserving surgery is not an option. There is a lack of evidence showing an advantage of mastectomy plus IBR over mastectomy alone on health-related quality of life (QoL). METHODS: A large prospective multicentre survey, STIC-RMI (support of innovative and expensive techniques - immediate breast reconstruction), was undertaken to study the changes in QoL in patients treated by mastectomy with or without IBR...
April 12, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28401534/competing-risks-analysis-of-microsatellite-instability-as-a-prognostic-factor-in-colorectal-cancer
#5
J Toh, P H Chapuis, L Bokey, C Chan, K J Spring, O F Dent
BACKGROUND: Despite an extensive literature suggesting that high microsatellite instability (MSI-H) enhances survival and protects against recurrence after colorectal cancer resection, such effects remain controversial as many studies show only a weak bivariate association or no multivariable association with outcome. This study examined the relationship between MSI status and colorectal cancer outcomes with adjustment for death from other causes as a competing risk. METHODS: A hospital database of patients following colorectal cancer resection was interrogated for clinical, operative, pathology, adjuvant therapy and follow-up information...
April 12, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28401533/long-term-follow-up-of-fenestrated-endovascular-repair-for-juxtarenal-aortic-aneurysm
#6
I N Roy, A M Millen, S M Jones, S R Vallabhaneni, J R H Scurr, R G McWilliams, J A Brennan, R K Fisher
BACKGROUND: Fenestrated endovascular aneurysm repair (FEVAR) is increasingly being used for juxtarenal aortic aneurysms. The aim of this study was to review long-term results and assess the importance of changing stent-graft design on outcomes. METHODS: This was a retrospective review of all patients who underwent FEVAR within a single unit over 12 years (February 2003 to December 2015). Kaplan-Meier analysis of survival, and freedom from target vessel loss, aneurysm expansion, graft-related endoleak and secondary intervention was performed...
April 12, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28394402/dual-hypothermic-oxygenated-machine-perfusion-in-liver-transplants-donated-after-circulatory-death
#7
R van Rijn, N Karimian, A P M Matton, L C Burlage, A C Westerkamp, A P van den Berg, R H J de Kleine, M T de Boer, T Lisman, R J Porte
BACKGROUND: Experimental studies have suggested that end-ischaemic dual hypothermic oxygenated machine perfusion (DHOPE) may restore hepatocellular energy status and reduce reperfusion injury in donation after circulatory death (DCD) liver grafts. The aim of this prospective case-control study was to assess the safety and feasibility of DHOPE in DCD liver transplantation. METHODS: In consecutive DCD liver transplantations, liver grafts were treated with end-ischaemic DHOPE...
April 10, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28379607/randomized-clinical-trial-of-autologous-skin-cell-suspension-for-accelerating-re-epithelialization-of-split-thickness-donor-sites
#8
Z Hu, D Guo, P Liu, X Cao, S Li, J Zhu, B Tang
BACKGROUND: Split-thickness skin graft (STSG) is used frequently, but may result in complications at the donor site. Rapid healing of donor-site wounds is critical to relieving morbidity. This study investigated whether autologous skin cell suspension could improve healing of STSG donor-site wounds. METHODS: Between September 2014 and February 2016, patients requiring STSGs were randomized to receive autologous skin cell suspension plus hydrocolloid dressings (experimental group) or hydrocolloid dressings alone (control group) for the donor site...
April 5, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28378448/population-based-study-demonstrating-an-increase-in-colorectal-cancer-in-young-patients
#9
J Gandhi, C Davidson, C Hall, J Pearson, T Eglinton, C Wakeman, F Frizelle
BACKGROUND: New Zealand has among the highest rates of colorectal cancer in the world and is an unscreened population. The aim of this study was to determine the trends in incidence and tumour location in the New Zealand population before the introduction of national colorectal cancer screening. METHODS: Data were obtained from the national cancer registry and linked to population data from 1995 to 2012. Incidence rates for colorectal cancer by sex, age (less than 50 years, 50-79 years, 80 years or more) and location (proximal colon, distal colon and rectum) were assessed by linear regression...
April 5, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28376270/evaluation-of-the-peritoneal-carcinomatosis-index-with-ct-and-mri
#10
A Dohan, C Hoeffel, P Soyer, A S Jannot, P-J Valette, A Thivolet, G Passot, O Glehen, P Rousset
BACKGROUND: The aim was to determine the incremental value of MRI compared with CT in the preoperative estimation of the peritoneal carcinomatosis index (PCI). METHODS: CT and MRI examinations of patients with peritoneal carcinomatosis were evaluated. CT images were first analysed by two observers who determined a first PCI (PCICT ). Then, the two observers reviewed MRI examinations in combination with CT and determined a second PCI (PCICT   +   MRI ). The sensitivity and negative predictive value of the two imaging sets were determined using surgery as a reference standard (PCIRef )...
April 4, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28376246/non-technical-skills-of-surgeons-and-anaesthetists-in-simulated-operating-theatre-crises
#11
A G Doumouras, M Hamidi, K Lung, C L Tarola, M W Tsao, J W Scott, D S Smink, S Yule
BACKGROUND: Deficiencies in non-technical skills (NTS) have been increasingly implicated in avoidable operating theatre errors. Accordingly, this study sought to characterize the impact of surgeon and anaesthetist non-technical skills on time to crisis resolution in a simulated operating theatre. METHODS: Non-technical skills were assessed during 26 simulated crises (haemorrhage and airway emergency) performed by surgical teams. Teams consisted of surgeons, anaesthetists and nurses...
April 4, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28376245/geographic-and-socioeconomic-factors-affecting-delivery-of-bariatric-surgery-across-high-and-low-utilization-healthcare-systems
#12
A G Doumouras, F Saleh, A M Sharma, S Anvari, S Gmora, M Anvari, D Hong
BACKGROUND: In countries with universal health coverage, the delivery of care should be driven by need. However, other factors, such as proximity to local facilities or neighbourhood socioeconomic status, may be more important. The objective of this study was to evaluate which geographic and socioeconomic factors affect the delivery of bariatric care in Canada. METHODS: This was a national retrospective cohort study of all adult patients undergoing bariatric surgery between April 2008 and March 2015 in Canada (excluding Quebec)...
April 4, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28376235/survival-analysis-of-the-ceawatch-multicentre-clustered-randomized-trial
#13
C J Verberne, Z Zhan, E R van den Heuvel, F Oppers, A M de Jong, I Grossmann, J M Klaase, G H de Bock, T Wiggers
BACKGROUND: The CEAwatch randomized trial showed that follow-up with intensive carcinoembryonic antigen (CEA) monitoring (CEAwatch protocol) was better than care as usual (CAU) for early postoperative detection of colorectal cancer recurrence. The aim of this study was to calculate overall survival (OS) and disease-specific survival (DSS). METHODS: For all patients with recurrence, OS and DSS were compared between patients detected by the CEAwatch protocol versus CAU, and by the method of detection of recurrence, using Cox regression models...
April 4, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28369809/prospective-trial-to-evaluate-the-prognostic-value-of-different-nutritional-assessment-scores-in-pancreatic-surgery-nurimas-pancreas
#14
P Probst, S Haller, T Bruckner, A Ulrich, O Strobel, T Hackert, M K Diener, M W Büchler, P Knebel
BACKGROUND: Preoperative nutritional status has an impact on patients' clinical outcome. For pancreatic surgery, however, it is unclear which nutritional assessment scores adequately assess malnutrition associated with postoperative outcome. METHODS: Patients scheduled for elective pancreatic surgery at the University of Heidelberg were screened for eligibility. Twelve nutritional assessment scores were calculated before operation, and patients were categorized as either at risk or not at risk for malnutrition by each score...
March 30, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28332700/the-evolution-of-informed-consent
#15
R Wheeler
No abstract text is available yet for this article.
March 23, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28326535/effect-of-day-of-the-week-on-short-and-long-term-mortality-after-emergency-general-surgery
#16
M A Gillies, N I Lone, R M Pearse, C Haddow, L Smyth, R W Parks, T S Walsh, E M Harrison
BACKGROUND: The effect of day of the week on outcome after surgery is the subject of debate. The aim was to determine whether day of the week of emergency general surgery alters short- and long-term mortality. METHODS: This was an observational study of all patients undergoing emergency general surgery in Scotland between 1 January 2005 and 31 December 2007, followed to 2012. Multilevel logistic and Cox proportional hazards regression were used to assess the effect of day of the week of surgery on outcome after adjustment for case mix and risk factors...
March 21, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28300279/prehabilitation-in-perioperative-care
#17
K Moorthy, V Wynter-Blyth
No abstract text is available yet for this article.
March 16, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28300277/breast-cancer-and-genomic-testing
#18
C Liedtke, H-C Kolberg
No abstract text is available yet for this article.
March 16, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28300274/damage-control-laparotomy-in-trauma
#19
S D Jensen, B A Cotton
No abstract text is available yet for this article.
March 16, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28295219/patterns-predictive-factors-and-prognostic-impact-of-multilevel-metastasis-in-n1b-papillary-thyroid-carcinoma
#20
S K Kim, I Park, N Hur, J-H Choe, J-H Kim, J S Kim
BACKGROUND: The patterns, predictive factors and prognostic impact of multilevel metastasis in patients with N1b papillary thyroid carcinoma (PTC) were investigated. METHODS: A retrospective review of patients with N1b PTC from a tertiary referral centre in Korea who underwent unilateral modified radical neck dissection was undertaken. RESULTS: Of 658 patients, multilevel metastasis was found in 73·9 per cent; the most common type was metastasis in two levels...
March 15, 2017: British Journal of Surgery
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