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British Journal of Psychiatry: the Journal of Mental Science

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https://www.readbyqxmd.com/read/29991358/prolonged-exposure-therapy-and-supportive-counselling-for-post-traumatic-stress-disorder-in-adolescents-task-shifting-randomised-controlled-trial
#1
Jaco Rossouw, Elna Yadin, Debra Alexander, Soraya Seedat
BACKGROUND: Empirical evidence on the effectiveness of evidence-based treatments for adolescents with post-traumatic stress disorder (PTSD) in low-resource settings is needed.AimsTo evaluate the comparative effectiveness of prolonged exposure and supportive counselling in adolescents with PTSD. METHOD: Sixty-three adolescents (13-18 years) with PTSD were randomly assigned to receive either of the interventions comprising 7-14 sessions of treatment (trial registration in the Pan African Clinical Trials Registry: PACTR201511001345372)...
July 11, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29986772/absence-of-cerebrospinal-fluid-antineuronal-antibodies-in-schizophrenia-spectrum-disorders-corrigendum
#2
Tatiana Oviedo-Salcedo, Lot de Witte, Tania Kümpfel, René S Kahn, Peter Falkai, Peter Eichhorn, Jurjen Luykx, Alkomiet Hasan
SummaryThis notice describes a correction to the above mentioned paper.
July 10, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29957167/young-adult-mental-health-and-functional-outcomes-among-individuals-with-remitted-persistent-and-late-onset-adhd
#3
Jessica C Agnew-Blais, Guilherme V Polanczyk, Andrea Danese, Jasmin Wertz, Terrie E Moffitt, Louise Arseneault
BACKGROUND: Attention-deficit hyperactivity disorder (ADHD) is associated with mental health problems and functional impairment across many domains. However, how the longitudinal course of ADHD affects later functioning remains unclear.AimsWe aimed to disentangle how ADHD developmental patterns are associated with young adult functioning. METHOD: The Environmental Risk (E-Risk) Longitudinal Twin Study is a population-based cohort of 2232 twins born in England and Wales in 1994-1995...
June 29, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29952277/predicting-antidepressant-response-by-monitoring-early-improvement-of-individual-symptoms-of-depression-individual-patient-data-meta-analysis
#4
Ymkje Anna de Vries, Annelieke M Roest, Elisabeth H Bos, Johannes G M Burgerhof, Hanna M van Loo, Peter de Jonge
BACKGROUND: Improvement in depression within the first 2 weeks of antidepressant treatment predicts good outcomes, but non-improvers can still respond or remit, whereas improvers often do not.AimsWe aimed to investigate whether early improvement of individual depressive symptoms better predicts response or remission. METHOD: We obtained individual patient data of 30 trials comprising 2184 placebo-treated and 6058 antidepressant-treated participants. Primary outcome was week 6 response; secondary outcomes were week 6 remission and week 12 response and remission...
June 28, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29941055/a-systematic-scoping-review-of-psychological-therapies-for-psychosis-within-acute-psychiatric-in-patient-settings
#5
Pamela Jacobsen, Kathleen Hodkinson, Emmanuelle Peters, Paul Chadwick
BACKGROUND: People with psychotic disorders account for most acute admissions to psychiatric wards. Psychological therapies are a treatment adjunct to standard medication and nursing care, but the evidence base for such therapies within in-patient settings is unclear.AimsTo conduct a systematic scoping review of the current evidence base for psychological therapies for psychosis delivered within acute in-patient settings (PROSPERO: CRD42015025623). METHOD: All study designs, and therapy models, were eligible for inclusion in the review...
August 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29925436/attention-deficit-hyperactivity-disorder-and-anxiety-disorders-as-precursors-of-bipolar-disorder-onset-in-adulthood
#6
Sandra M Meier, Barbara Pavlova, Søren Dalsgaard, Merete Nordentoft, Ole Mors, Preben B Mortensen, Rudolf Uher
BACKGROUND: Attention-deficit hyperactivity disorder (ADHD) and anxiety disorders have been proposed as precursors of bipolar disorder, but their joint and relative roles in the development of bipolar disorder are unknown.AimsTo test the prospective relationship of ADHD and anxiety with onset of bipolar disorder. METHOD: We examined the relationship between ADHD, anxiety disorders and bipolar disorder in a birth cohort of 2 409 236 individuals born in Denmark between 1955 and 1991...
June 21, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29909778/unwell-in-hospital-but-not-incapable-cross-sectional-study-on-the-dissociation-of-decision-making-capacity-for-treatment-and-research-in-in-patients-with-schizophrenia-and-related-psychoses
#7
Benjamin Walter Jack Spencer, Tania Gergel, Matthew Hotopf, Gareth S Owen
BACKGROUND: Consent to research with decision-making capacity for research (DMC-R) is normally a requirement for study participation. Although the symptoms of schizophrenia and related psychoses are known to affect decision-making capacity for treatment (DMC-T), we know little about their effect on DMC-R.AimsWe aimed to determine if DMC-R differs from DMC-T in proportion and associated symptoms in an in-patient sample of people with schizophrenia and related psychoses. METHOD: Cross-sectional study of psychiatric in-patients admitted for assessment and/or treatment of schizophrenia and related psychoses...
June 18, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29898791/diagnosed-depression-and-sociodemographic-factors-as-predictors-of-mortality-in-patients-with-dementia
#8
Gemma Lewis, Nomi Werbeloff, Joseph F Hayes, Robert Howard, David P J Osborn
BACKGROUND: Potentially modifiable risk factors for developing dementia have been identified. However, risk factors for increased mortality in patients with diagnosed dementia are not well understood. Identifying factors that influence prognosis would help clinicians plan care and address unmet needs.AimsTo investigate diagnosed depression and sociodemographic factors as predictors of mortality in patients with dementia in UK secondary clinical care services. METHOD: We conducted a cohort study of patients with a dementia diagnosis in an electronic health records database in a UK National Health Service mental health trust...
June 14, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29888682/application-of-n-of-1-treatment-trials-in-schizophrenia-systematic-review-erratum
#9
Katie F M Marwick, Anna J Stevenson, Caitlin Davies, Stephen M Lawrie
SummaryThis notice describes a correction to the above mentioned paper.
June 11, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29871707/remission-of-depression-in-patients-with-schizophrenia-and-comorbid-major-depressive-disorder-results-from-the-face-sz-cohort
#10
Guillaume Fond, Laurent Boyer, Fabrice Berna, Ophélia Godin, Ewa Bulzacka, Méja Andrianarisoa, Lore Brunel, Bruno Aouizerate, Delphine Capdevielle, Isabelle Chereau, Nathalie Coulon, Thierry D'Amato, Caroline Dubertret, Julien Dubreucq, Catherine Faget, Sylvain Leignier, Christophe Lançon, Jasmina Mallet, David Misdrahi, Christine Passerieux, Romain Rey, Aurélie Schandrin, Mathieu Urbach, Pierre Vidailhet, Marion Leboyer, Franck Schürhoff, Pierre-Michel Llorca
BACKGROUND: Major depressive disorder (MDD) is underdiagnosed and undertreated in schizophrenia, and has been strongly associated with impaired quality of life.AimsTo determine the prevalence and associated factors of MDD and unremitted MDD in schizophrenia, to compare treated and non-treated MDD. METHOD: Participants were included in the FondaMental Expert Centers for Schizophrenia and received a thorough clinical assessment. MDD was defined by a Calgary score ≥6...
August 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29764522/treatment-resistant-depression-and-peripheral-c-reactive-protein
#11
Samuel R Chamberlain, Jonathan Cavanagh, Peter de Boer, Valeria Mondelli, Declan N C Jones, Wayne C Drevets, Philip J Cowen, Neil A Harrison, Linda Pointon, Carmine M Pariante, Edward T Bullmore
BACKGROUND: C-reactive protein (CRP) is a candidate biomarker for major depressive disorder (MDD), but it is unclear how peripheral CRP levels relate to the heterogeneous clinical phenotypes of the disorder.AimTo explore CRP in MDD and its phenotypic associations. METHOD: We recruited 102 treatment-resistant patients with MDD currently experiencing depression, 48 treatment-responsive patients with MDD not currently experiencing depression, 48 patients with depression who were not receiving medication and 54 healthy volunteers...
May 16, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29761751/long-term-clinical-and-cost-effectiveness-of-collaborative-care-versus-usual-care-for-people-with-mental-physical-multimorbidity-cluster-randomised-trial
#12
Elizabeth M Camacho, Linda M Davies, Mark Hann, Nicola Small, Peter Bower, Carolyn Chew-Graham, Clare Baguely, Linda Gask, Chris M Dickens, Karina Lovell, Waquas Waheed, Chris J Gibbons, Peter Coventry
BACKGROUND: Collaborative care can support the treatment of depression in people with long-term conditions, but long-term benefits and costs are unknown.AimsTo explore the long-term (24-month) effectiveness and cost-effectiveness of collaborative care in people with mental-physical multimorbidity. METHOD: A cluster randomised trial compared collaborative care (integrated physical and mental healthcare) with usual care for depression alongside diabetes and/or coronary heart disease...
May 15, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29739481/ventromedial-prefrontal-cortex-activity-and-pathological-worry-in-generalised-anxiety-disorder
#13
E Via, M A Fullana, X Goldberg, D Tinoco-González, I Martínez-Zalacaín, C Soriano-Mas, C G Davey, J M Menchón, B Straube, T Kircher, J Pujol, N Cardoner, B J Harrison
BACKGROUND: Pathological worry is a hallmark feature of generalised anxiety disorder (GAD), associated with dysfunctional emotional processing. The ventromedial prefrontal cortex (vmPFC) is involved in the regulation of such processes, but the link between vmPFC emotional responses and pathological v. adaptive worry has not yet been examined.AimsTo study the association between worry and vmPFC activity evoked by the processing of learned safety and threat signals. METHOD: In total, 27 unmedicated patients with GAD and 56 healthy controls (HC) underwent a differential fear conditioning paradigm during functional magnetic resonance imaging...
May 9, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29947317/green-psychiatry-natural-environments-developmental-trauma-and-anxiety
#14
Kamaldeep Bhui
No abstract text is available yet for this article.
July 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29947316/are-we-ready-to-use-nature-gardens-to-treat-stress-related-illnesses
#15
Peter A Coventry, Piran C L White
SummaryIn this issue, Stigsdotter et al show that nature gardens offer similar benefits to cognitive-behavioural therapy for managing stress-related illnesses among people on sick leave. There is scope for pragmatic trials to establish the processes involved and highlight the co-benefits that nature gardens offer for health and the environment.Declaration of interestNone.
July 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29947315/assessment-of-decision-making-capacity-in-patients-requesting-assisted-suicide
#16
David Shaw, Manuel Trachsel, Bernice Elger
SummaryIn this editorial, we argue that current attitudes toward terminally ill patients are generally too paternalistic, and that it is wrong to assume that patients suffering from mental health issues (including depression) cannot consent to assisted suicide.Declaration of interestNone.
July 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29947313/significant-concordance-of-genetic-variation-that-increases-both-the-risk-for-obsessive-compulsive-disorder-and-the-volumes-of-the-nucleus-accumbens-and-putamen
#17
Derrek P Hibar, Joshua W Cheung, Sarah E Medland, Mary S Mufford, Neda Jahanshad, Shareefa Dalvie, Raj Ramesar, Evelyn Stewart, Odile A van den Heuvel, David L Pauls, James A Knowles, Dan J Stein, Paul M Thompson
BACKGROUND: Many studies have identified changes in the brain associated with obsessive-compulsive disorder (OCD), but few have examined the relationship between genetic determinants of OCD and brain variation.AimsWe present the first genome-wide investigation of overlapping genetic risk for OCD and genetic influences on subcortical brain structures. METHOD: Using single nucleotide polymorphism effect concordance analysis, we measured genetic overlap between the first genome-wide association study (GWAS) of OCD (1465 participants with OCD, 5557 controls) and recent GWASs of eight subcortical brain volumes (13 171 participants)...
July 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29852882/post-traumatic-stress-disorder-among-former-islamic-state-child-soldiers-in-northern-iraq
#18
Jan Ilhan Kizilhan, Michael Noll-Hussong
BACKGROUND: Former child soldiers are at high risk of developing mental disorders such as post-traumatic stress disorder (PTSD); however, their comprehensive mental health has yet to be examined.AimsThis study looks at the prevalence of PTSD, depression and associated risk factors such as disturbed self-esteem among former child soldiers of the so-called 'Islamic State'. METHOD: The psychological effect of traumatic events was assessed in 81 Yazidi children who had been child soldiers for the Islamic State in northern Iraq between 2014 and 2017 for at least 6 months...
July 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29804549/adolescent-affective-symptoms-and-mortality
#19
Gemma Archer, Diana Kuh, Matthew Hotopf, Mai Stafford, Marcus Richards
BACKGROUND: Little is known about the relationship between adolescent affective problems (anxiety and depression) and mortality.AimsTo examine whether adolescent affective symptoms are associated with premature mortality, and to assess whether this relationship is independent of other developmental factors. METHOD: Data (n = 3884) was from Britain's oldest birth cohort study - the National Survey of Health and Development. Adolescent affective symptoms were rated by teachers at ages 13 and 15 years: scores were summed and classified into three categories: mild or no, moderate and severe symptoms (1st-50th, 51st-90th and 91st-100th percentiles, respectively)...
July 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29793558/efficacy-of-nature-based-therapy-for-individuals-with-stress-related-illnesses-randomised-controlled-trial
#20
Ulrika Karlsson Stigsdotter, Sus Sola Corazon, Ulrik Sidenius, Patrik Karlsson Nyed, Helmer Bøving Larsen, Lone Overby Fjorback
BACKGROUND: Stress-related illnesses are a major threat to public health, and there is increasing demand for validated treatments.AimsTo test the efficacy of nature-based therapy (NBT) for patients with stress-related illnesses. METHOD: Randomised controlled trial (ClinicalTrials.gov ID NCT01849718) comparing Nacadia® NBT (NNBT) with the cognitive-behavioural therapy known as Specialised Treatment for Severe Bodily Distress Syndromes (STreSS). In total, 84 participants were randomly allocated to one of the two treatments...
July 2018: British Journal of Psychiatry: the Journal of Mental Science
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