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British Journal of Psychiatry: the Journal of Mental Science

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https://www.readbyqxmd.com/read/28729357/association-between-maternal-childhood-trauma-and-offspring-childhood-psychopathology-mediation-analysis-from-the-alspac-cohort
#1
Dominic T Plant, Fergal W Jones, Carmine M Pariante, Susan Pawlby
BackgroundStudies have shown that a mother's history of child maltreatment is associated with her child's experience of internalising and externalising difficulties.AimsTo characterise the mediating pathways that underpin this association.MethodData on a mother's history of child maltreatment, depression during pregnancy, postnatal depression, maladaptive parenting practices and her child's experience of maltreatment and internalising and externalising difficulties were analysed in an Avon Longitudinal Study of Parents and Children (ALSPAC) sample of 9397 mother-child dyads followed prospectively from pregnancy to age 13...
July 20, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28729356/influence-of-childhood-trauma-on-diagnosis-and-substance-use-in-first-episode-psychosis
#2
S Tomassi, S Tosato, V Mondelli, C Faravelli, A Lasalvia, G Fioravanti, C Bonetto, A Fioritti, C Cremonese, R Lo Parrino, K De Santi, A Meneghelli, S Torresani, G De Girolamo, E Semrov, M Pratelli, D Cristofalo, M Ruggeri
BackgroundChildhood trauma has been significantly associated with first-episode psychosis, affective dysfunction and substance use.AimsTo test whether people with first-episode psychosis who had experienced childhood trauma, when compared with those who had not, showed a higher rate of affective psychosis and an increased lifetime rate of substance use.MethodThe sample comprised 345 participants with first-episode psychosis (58% male, mean age 29.8 years, s.d. = 9.7).ResultsSevere sexual abuse was significantly associated with a diagnosis of affective psychosis (χ(2) = 4...
July 20, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28684405/sleep-loss-as-a-trigger-of-mood-episodes-in-bipolar-disorder-individual-differences-based-on-diagnostic-subtype-and-gender
#3
Katie Swaden Lewis, Katherine Gordon-Smith, Liz Forty, Arianna Di Florio, Nick Craddock, Lisa Jones, Ian Jones
BackgroundSleep loss may trigger mood episodes in people with bipolar disorder but individual differences could influence vulnerability to this trigger.AimsTo determine whether bipolar subtype (bipolar disorder type I (BP-I) or II (BD-II)) and gender were associated with vulnerability to the sleep loss trigger.MethodDuring a semi-structured interview, 3140 individuals (68% women) with bipolar disorder (66% BD-I) reported whether sleep loss had triggered episodes of high or low mood. DSM-IV diagnosis of bipolar subtype was derived from case notes and interview data...
July 6, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28684404/depressive-and-anxious-symptoms-and-the-risk-of-secondary-school-non-completion
#4
Frédéric N Brière, Sophie Pascal, Véronique Dupéré, Natalie Castellanos-Ryan, Francis Allard, Gabrielle Yale-Soulière, Michel Janosz
BackgroundEvidence regarding the association between adolescent internalising symptoms and school non-completion has been limited and inconclusive.AimsTo examine whether depressive and anxious symptoms at secondary school entry predict school non-completion beyond confounders and whether associations differ by baseline academic functioning.MethodWe used logistic regression to examine associations between depressive and anxious symptoms in grade 7 (age 12-14) and school non-completion (age 18-20) in 4962 adolescents...
July 6, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28684403/mortality-gap-for-people-with-bipolar-disorder-and-schizophrenia-uk-based-cohort-study-2000-2014
#5
Joseph F Hayes, Louise Marston, Kate Walters, Michael B King, David P J Osborn
BackgroundBipolar disorder and schizophrenia are associated with increased mortality relative to the general population. There is an international emphasis on decreasing this excess mortality.AimsTo determine whether the mortality gap between individuals with bipolar disorder and schizophrenia and the general population has decreased.MethodA nationally representative cohort study using primary care electronic health records from 2000 to 2014, comparing all patients diagnosed with bipolar disorder or schizophrenia and the general population...
July 6, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28642259/staff-experiences-and-perceptions-of-working-with-in-patients-who-are-suicidal-qualitative-analysis
#6
Yvonne Awenat, Sarah Peters, Emma Shaw-Nunez, Patricia Gooding, Daniel Pratt, Gillian Haddock
BackgroundSuicidal behaviour is frequent in psychiatric in-patients and much staff time and resources are devoted to assessing and managing suicide risk. However, little is known about staff experiences of working with in-patients who are suicidal.AimsTo investigate staff experiences of working with in-patients who are suicidal.MethodQualitative study guided by thematic analysis of semi-structured interviews with mental health staff with experience of psychiatric in-patient care.ResultsTwenty staff participated...
June 22, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28642258/ethnicity-and-long-term-course-and-outcome-of-psychotic-disorders-in-a-uk-sample-the-%C3%A3-sop-10-study
#7
Craig Morgan, Paul Fearon, Julia Lappin, Margaret Heslin, Kim Donoghue, Ben Lomas, Ulrich Reininghaus, Adanna Onyejiaka, Tim Croudace, Peter B Jones, Robin M Murray, Gillian A Doody, Paola Dazzan
BackgroundThe incidence of psychotic disorders is elevated in some minority ethnic populations. However, we know little about the outcome of psychoses in these populations.AimsTo investigate patterns and determinants of long-term course and outcome of psychoses by ethnic group following a first episode.MethodÆSOP-10 is a 10-year follow-up of an ethnically diverse cohort of 532 individuals with first-episode psychosis identified in the UK. Information was collected, at baseline, on clinical presentation and neurodevelopmental and social factors and, at follow-up, on course and outcome...
June 22, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28642257/interaction-between-the-fto-gene-body-mass-index-and-depression-meta-analysis-of-13701-individuals
#8
REVIEW
Margarita Rivera, Adam E Locke, Tanguy Corre, Darina Czamara, Christiane Wolf, Ana Ching-Lopez, Yuri Milaneschi, Stefan Kloiber, Sara Cohen-Woods, James Rucker, Katherine J Aitchison, Sven Bergmann, Dorret I Boomsma, Nick Craddock, Michael Gill, Florian Holsboer, Jouke-Jan Hottenga, Ania Korszun, Zoltan Kutalik, Susanne Lucae, Wolfgang Maier, Ole Mors, Bertram Müller-Myhsok, Michael J Owen, Brenda W J H Penninx, Martin Preisig, John Rice, Marcella Rietschel, Federica Tozzi, Rudolf Uher, Peter Vollenweider, Gerard Waeber, Gonneke Willemsen, Ian W Craig, Anne E Farmer, Cathryn M Lewis, Gerome Breen, Peter McGuffin
BackgroundDepression and obesity are highly prevalent, and major impacts on public health frequently co-occur. Recently, we reported that having depression moderates the effect of the FTO gene, suggesting its implication in the association between depression and obesity.AimsTo confirm these findings by investigating the FTO polymorphism rs9939609 in new cohorts, and subsequently in a meta-analysis.MethodThe sample consists of 6902 individuals with depression and 6799 controls from three replication cohorts and two original discovery cohorts...
June 22, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28596245/computerised-cognitive-behavioural-therapy-for-adults-with-intellectual-disability-randomised-controlled-trial
#9
Patricia Cooney, Catherine Jackman, David Coyle, Gary O'Reilly
BackgroundDespite the evidence base for computer-assisted cognitive-behavioural therapy (CBT) in the general population, it has not yet been adapted for use with adults who have an intellectual disability.AimsTo evaluate the utility of a CBT computer game for adults who have an intellectual disability.MethodA 2×3 (group×time) randomised controlled trial design was used. Fifty-two adults with mild to moderate intellectual disability and anxiety or depression were randomly allocated to two groups: computerised CBT (cCBT) or psychiatric treatment as usual (TAU), and assessed at pre-treatment, post-treatment and 3-month follow-up...
June 8, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28522435/navigating-the-challenges-of-digital-health-innovation-considerations-and-solutions-in-developing-online-and-smartphone-application-based-interventions-for-mental-health-disorders
#10
Claire Hill, Jennifer L Martin, Simon Thomson, Nick Scott-Ram, Hugh Penfold, Cathy Creswell
This article presents an analysis of challenges and considerations when developing digital mental health innovations. Recommendations include collaborative working between clinicians, researchers, industry and service users in order to successfully navigate challenges and to ensure e-therapies are engaging, acceptable, evidence based, scalable and sustainable.
May 18, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28522434/one-year-symptom-trajectories-in-patients-with-stable-schizophrenia-maintained-on-antipsychotics-versus-placebo-meta-analysis
#11
REVIEW
Hiroyoshi Takeuchi, Navot Kantor, Marcos Sanches, Gagan Fervaha, Ofer Agid, Gary Remington
BackgroundAs definitions of relapse differ substantially between studies, in investigations involving data aggregation, total scores on clinical rating scales provide a more generalisable outcome.AimsTo compare total symptom trajectories for antipsychotic versus placebo treatment over a 1-year period of maintenance treatment in schizophrenia.MethodRandomised controlled trials with antipsychotic and placebo treatment arms in patients with stable schizophrenia that reported Positive and Negative Syndrome Scale and Brief Psychiatric Rating Scale total scores at more than one time point were included...
May 18, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28522433/beneficial-and-harmful-effects-of-educative-suicide-prevention-websites-randomised-controlled-trial-exploring-papageno-v-werther-effects
#12
Benedikt Till, Ulrich S Tran, Martin Voracek, Thomas Niederkrotenthaler
BackgroundSuicide prevention organisations frequently use websites to educate the public, but evaluations of these websites are lacking.AimsTo examine the effects of educative websites and the moderating effect of participant vulnerability.MethodA total of 161 adults were randomised to either view an educative website on suicide prevention or an unrelated website in a single-blinded randomised controlled trial (trial registration with the American Economic Association's registry: RCT-ID: 000924). The primary outcome was suicidal ideation; secondary outcomes were mood, suicide-prevention-related knowledge and attitudes towards suicide/seeking professional help...
May 18, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28473319/clinical-utility-of-magnetic-resonance-imaging-in-first-episode-psychosis
#13
Irina Falkenberg, Stefania Benetti, Marie Raffin, Phillipe Wuyts, William Pettersson-Yeo, Paola Dazzan, Kevin D Morgan, Robin M Murray, Tiago Reis Marques, Anthony S David, Jozef Jarosz, Andrew Simmons, Steve Williams, Philip McGuire
BackgroundThere is no consensus as to whether magnetic resonance imaging (MRI) should be used as part of the initial clinical evaluation of patients with first-episode psychosis (FEP).Aims(a) To assess the logistical feasibility of routine MRI; (b) to define the clinical significance of radiological abnormalities in patients with FEP.MethodRadiological reports from MRI scans of two FEP samples were reviewed; one comprised 108 patients and 98 healthy controls recruited to a research study and the other comprised 241 patients scanned at initial clinical presentation plus 66 healthy controls...
May 4, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28673956/plasticity-and-optimism-in-psychiatric-research-and-practice
#14
EDITORIAL
Kamaldeep Bhui
No abstract text is available yet for this article.
July 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28673955/kaleidoscope
#15
Derek K Tracy, Dan W Joyce, Sukhwinder S Shergill
No abstract text is available yet for this article.
July 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28673954/mental-illness-human-rights-and-the-law
#16
Anthony Zigmond
No abstract text is available yet for this article.
July 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28673953/on-call-geriatric-psychiatry-handbook-of-principles-and-practice
#17
Kathryn Milward
No abstract text is available yet for this article.
July 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28673952/rational-suicide-in-the-elderly-clinical-ethical-and-sociocultural-aspects
#18
Julian C Hughes
No abstract text is available yet for this article.
July 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28673951/the-lunatic-house-guy-s-hospital-london-of-1797-psychiatry-in-pictures
#19
Richard H S Mindham
No abstract text is available yet for this article.
July 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28673950/authors-reply
#20
Kate M Chitty, Geoffrey K Isbister, Andrew H Dawson, Nicholas A Buckley
No abstract text is available yet for this article.
July 2017: British Journal of Psychiatry: the Journal of Mental Science
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