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British Journal of Ophthalmology

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https://www.readbyqxmd.com/read/28625972/prevalence-subtypes-severity-and-determinants-of-ocular-trauma-the-singapore-chinese-eye-study
#1
Mark Yz Wong, Ryan Ek Man, Preeti Gupta, Charumathi Sabanayagam, Tien Yin Wong, Ching-Yu Cheng, Ecosse Luc Lamoureux
PURPOSE: To describe the prevalence, subtypes, severity and determinants of ocular trauma (OT) in a population-based study in Singapore. METHODS: We included 3353 Chinese adults aged ≥40 years from the Singapore Chinese Eye Study, a population-based study, conducted between 2009 and 2011. OT was defined as self-reported history of any eye injury requiring medical attention with or without hospitalisation, and further classified as blunt object, sharp object or chemical burns related...
June 16, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28625971/peripheral-leptochoroid-clinical-and-anatomical-findings
#2
Jasmine H Francis, Larissa A Habib, David H Abramson
BACKGROUND/AIMS: To investigate the clinical findings and anatomical characteristics of patients with a thinned peripheral choroid (leptochoroid) presenting with bilateral macular geographical hyperpigmented fundus and compare with matched controls. METHODS: A retrospective, observational case series of 44 eyes (24 patients): 22 study eyes (12 study patients) with clinical findings of leptochoroid (geographical hyperpigmented fundus centred in the macula) matched with 22 control eyes (12 control patients)...
June 16, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28611133/long-term-clinical-outcome-of-femtosecond-laser-assisted-lamellar-keratectomy-with-phototherapeutic-keratectomy-in-anterior-corneal-stromal-dystrophy
#3
Jonghyun Lee, Jin Hyoung Kim, Doh Lee, Ji Woong Chang, Joo Youn Shin, Ji Won Seo, Min Hwan Seo, Nam Ju Moon
PURPOSE: To evaluate long-term outcome of femtosecond laser-assisted lamellar keratectomy (FLK) with phototherapeutic keratectomy (PTK) in patients with anterior corneal stromal dystrophies. METHODS: A total of 10 eyes from seven patients who underwent FLK were included. The patients had suffered from recurrent corneal erosion or visual disturbance in anterior corneal dystrophies (five Avellino dystrophies and two lattice dystrophies). Planar-shaped lamellar keratectomy was performed using femtosecond laser...
June 13, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28611132/posterior-chamber-phakic-intraocular-lens-implantation-comparative-multicentre-study-in-351-eyes-with-low-to-moderate-or-high-myopia
#4
Kazutaka Kamiya, Kimiya Shimizu, Akihito Igarashi, Yoshihiro Kitazawa, Takashi Kojima, Tomoaki Nakamura, Yoshitaka Oka, Rei Matsumoto
AIM: To compare the clinical outcomes of posterior chamber phakic intraocular lens implantation with a central hole (Hole Implantable Collamer Lens (ICL), STAAR Surgical) for low-to-moderate myopia and for high myopia. METHODS: This multicentre retrospective case series comprised 351 eyes of 351 consecutive patients undergoing ICL implantation. Eyes were divided into groups based on preoperative degree of myopia: group 1; 57 eyes, manifest spherical equivalent less than -6 dioptres (D), and group 2; 294 eyes, -6 D or more...
June 13, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28611131/a-retrospective-study-on-the-incidence-of-post-cataract-surgery-descemet-s-membrane-detachment-and-outcome-of-air-descemetopexy
#5
Annamalai Odayappan, Narayana Shivananda, Seema Ramakrishnan, Tiruvengada Krishnan, Sivagami Nachiappan, Smitha Krishnamurthy
PURPOSE: To study the anatomic and functional outcome of air descemetopexy in postcataract surgery Descemet's membrane detachment (DMD). DESIGN: Retrospective study. METHODS: Setting: Institutional. STUDY POPULATION: Records of 112 patients who underwent air descemetopexy for postcataract surgery sight-threatening DMD at Aravind Eye Hospital, Pondicherry, between January 2013 and December 2015 were studied. MAIN OUTCOME MEASURES: Anatomical outcome refers to reattachment of the Descemet's membrane (DM)...
June 13, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28607177/burden-of-vision-loss-associated-with-eye-disease-in-china-1990-2020-findings-from-the-global-burden-of-disease-study-2015
#6
Bingsong Wang, Nathan Congdon, Rupert Bourne, Yichong Li, Kai Cao, Aiping Zhao, Mayinuer Yusufu, Wenlan Dong, Maigeng Zhou, Ningli Wang
AIMS: To assess the burden of vision loss due to eye disease in China between 1990 and 2015, and to predict the burden in 2020. METHODS: Data from the GBD 2015 (Global Burden of Diseases, Injuries, and Risk Factors Study 2015) were used. The main outcome measures were prevalence and years lived with disability (YLDs) for vision loss due to cataract, glaucoma, macular degeneration, other vision loss, refraction and accommodation disorders and trachoma. RESULTS: Prevalence for eye diseases increased steadily from 1990 to 2015, and will increase until 2020...
June 12, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28607176/clinical-features-of-hla-b27-positive-acute-anterior-uveitis-with-or-without-ankylosing-spondylitis-in-a-chinese-cohort
#7
Peizeng Yang, Wenjuan Wan, Liping Du, Qingyun Zhou, Jian Qi, Liang Liang, Chaokui Wang, Lili Wu, Aize Kijlstra
AIMS: To characterise the clinical features of human leucocyte antigen (HLA)-B27(+)acute anterior uveitis (AAU) patients with or without ankylosing spondylitis (AS) and investigate the retinal vascular involvement in these patients. METHODS: A total of 1056 HLA-B27(+) AAU patients (1525 eyes) were retrospectively studied from April 2008 to February 2016. Patients were divided into human leucocyte antigen (HLA)-B27(+)AS(+) and HLA-B27(+)AS(-) group. Clinical features including the onset of uveitis, laterality, the age at first attack, clinical examinations, best corrected visual acuity (BCVA), abnormalities in fundus fluorescence angiography (FFA) and complications were determined and compared between these two groups...
June 12, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28607175/environmental-factors-explain-socioeconomic-prevalence-differences-in-myopia-in-6-year-old-children
#8
J Willem L Tideman, Jan Roelof Polling, Albert Hofman, Vincent Wv Jaddoe, Johan P Mackenbach, Caroline Cw Klaver
PURPOSE: High myopia (≤-6 D) usually has its onset before 10 years of age and can lead to blinding complications later in life. We examined whether differences in myopia prevalences in socioeconomic risk groups could be explained by differences in lifestyle factors. METHODS: A total of 5711 six-year-old children participating in the prospective population-based birth cohort study Generation R underwent a stepwise ophthalmic examination, which included visual acuity and objective cycloplegic refraction to identify children with myopia (≤-0...
June 12, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28607174/aqueous-humour-dynamics-and-biometrics-in-the-ageing-chinese-eye
#9
Tao Guo, Sruthi Sampathkumar, Shan Fan, Nathan Morris, Fang Wang, Carol B Toris
AIMS: This study evaluates ocular biometrics and aqueous humour dynamics (AHD) in healthy Chinese volunteers to determine how the various ocular parameters interact to maintain physiological intraocular pressure (IOP) at all ages. METHODS: Sixty-nine volunteers enrolled in this cross-sectional study and were categorised into young (20-30 years) and old (≥50 years) groups. Measurements included IOP, ocular biometrics and AHD. Data were analysed using mixed model with random sampling to account for both eyes from the same individual...
June 12, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28600304/second-primary-malignancies-in-retinoblastoma-patients-treated-with-intra-arterial-chemotherapy-the-first-10-years
#10
Larissa A Habib, Jasmine H Francis, Armida Wm Fabius, Pierre Y Gobin, Ira J Dunkel, David H Abramson
BACKGROUND/AIMS: Survivors of retinoblastoma carry a lifetime risk of secondary malignancies. It is well established that external beam radiation increases this risk; however, the risk with ophthalmic artery chemosurgery (OAC) remains unknown. We report on 10 years of experience with OAC and the rate of second primary malignancy (SPM) development. METHODS: This is a single-centre retrospective review approved by the Memorial Sloan Kettering Cancer Center Institutional Review Board of all patients who received OAC over a 10-year period, from May 2006 to November 2016...
June 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28600303/stability-of-visual-outcome-between-2-and-5-years-following-corneal-transplantation-in-the-uk
#11
Sing-Pey Chow, Cathy L Hopkinson, Derek M Tole, Mark N Jones, Stuart D Cook, W John Armitage
BACKGROUND AND AIMS: Many studies of corneal transplantation focus on graft failure or rejection as endpoints, or report visual outcomes at one postoperative time point. We aimed to study the stability of visual outcomes between 2 and 5 years following corneal transplantation. METHODS: All patients with keratoconus (868) or Fuchs endothelial dystrophy (FED) (569) receiving their first corneal transplant for visual purposes in the UK between January 2003 and December 2009 were included...
June 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28600302/use-of-ruthenium-106-brachytherapy-for-iris-melanoma-the-scottish-experience
#12
Umiya Agraval, Manvi Sobti, Heather C Russell, David Lockington, Diana Ritchie, Paul Cauchi, Ewan G Kemp, Vikas Chadha
PURPOSE: To analyse long-term outcomes of ruthenium-106 ((106)Ru) plaque brachytherapy for the treatment of iris melanoma. METHODS: We retrospectively reviewed medical records of 19 consecutive patients with pure iris melanoma treated with (106)Ru plaque brachytherapy between 1998 and 2016 at the Scottish Ophthalmic Oncology Service, Glasgow. The iris melanoma was treated with a ruthenium plaque placed on the corneal surface to deliver a surface dose of 555 Gy. We analysed vision preservation, local tumour control, radiation-related complications, eye retention rates, symptomatic metastasis and melanoma-related mortality...
June 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28600301/features-of-optical-coherence-tomography-predictive-of-choroidal-neovascularisation-treatment-response-in-pathological-myopia-in-association-with-fluorescein-angiography
#13
Dong Hyun Lee, Hyun Goo Kang, Sung Chul Lee, Min Kim
BACKGROUND/AIMS: The aim of this study was to evaluate the usefulness of several optical coherence tomography (OCT) findings to estimate choroidal neovascularisation (CNV) activity in pathological myopia using fluorescein angiography (FA) as a reference. METHODS: This was a single-centre, retrospective study. The medical records of patients with active myopic CNV who received intravitreal bevacizumab treatment were reviewed. Parameters to monitor CNV activity were morphological features of CNV on OCT, such as CNV height, central foveal thickness, intraretinal cysts, subretinal fluid, fuzziness of the CNV border, CNV network area on FA, and haemorrhage or exudation on fundus photo...
June 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28600300/retinal-vessels-functionality-in-eyes-with-central-serous-chorioretinopathy
#14
Livia Tomasso, Lucia Benatti, Alessandro Rabiolo, Adriano Carnevali, Ilaria Zucchiatti, Lea Querques, Francesco Bandello, Giuseppe Querques
PURPOSE: To analyse static characteristics and dynamic functionality of retinal vessels in eyes with central serous chorioretinopathy (CSCR) by means of Dynamic Vessel Analyzer (DVA). METHODS: Patients presenting with treatment-naïve CSCR and normal subjects (controls) matched for age and sex between May 2015 and November 2015 were enrolled in the study. Participants underwent a complete ophthalmological examination, including dynamic and static retinal vessels analysis by DVA...
June 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28600299/evaluation-of-optical-coherence-tomography-angiographic-findings-in-alzheimer-s-type-dementia
#15
Mehmet Bulut, Fatma Kurtuluş, Onursal Gözkaya, Muhammet Kazım Erol, Ayşe Cengiz, Melih Akıdan, Aylin Yaman
BACKGROUND/AIMS: To identify the retinal vascular pathologies in patients with Alzheimer's type dementia (ATD) through optical coherence tomography angiography (OCTA) imaging. METHODS: Our study included 26 patients in the patient group, and age-matched and sex-matched 26 subjects in the control group. A detailed ophthalmological and neurological examination was performed for all subjects included in the study. The retinal, choroidal vascular structures and choroidal thickness (CT) of all subjects were analysed in a detailed way with a commercial spectral domain OCTA...
June 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28600298/trematodal-granulomatous-uveitis-in-paediatric-egyptian-patients-a-case-series
#16
Amin Rm, Goweida Mb, El Goweini Hf, Bedda Am, Lotfy Wm, Gaballah Ah, Nadar Aa, Radwan Ae
PURPOSE: To describe the clinical presentations and results of laboratory analysis of waterborne ophthalmic granulomas of the anterior chamber (AC) in Egyptian patients. PARTICIPANTS: 110 patients with granulomatous anterior uveitis and distinctive AC nodules. DESIGN: Prospective, non-comparative, case series. METHODS: Demographic data including age, gender and place of residence were recorded. A full ophthalmic examination with emphasis on the inflammatory characteristics and systemic workup was performed...
June 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28596287/incidence-and-prevalence-of-uveitis-in-south-korea-a-nationwide-cohort-study
#17
Tyler Hyungtaek Rim, Sung Soo Kim, Don-Il Ham, Seung-Young Yu, Eun Jee Chung, Sung Chul Lee
AIM: To evaluate the incidence and prevalence of uveitis and associated risk factors in South Korea. METHODS: For this retrospective national cohort study, approximately 1 000 000 Korean residents were randomly selected from the Korean National Health Insurance Service database. Uveitis was defined according to the Korean Classification of Diseases. The uveitis incidence and prevalence were calculated. Sociodemographic factors and comorbidities associated with uveitis were evaluated via Cox proportional regression models...
June 8, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28596286/one-year-outcome-of-intravitreal-ziv-aflibercept-therapy-for-non-responsive-neovascular-age-related-macular-degeneration
#18
Imoro Zeba Braimah, Komal Agarwal, Ahmad Mansour, Jay Chhablani
AIM: To evaluate 12-month outcome of intravitreal ziv-aflibercept (IVZ) therapy in eyes with neovascular age-related macular degeneration (nAMD) that are non-responsive to bevacizumab and ranibizumab. METHODS: This retrospective study included 16 eyes (14 patients) with nAMD who were on prior treatment with bevacizumab and ranibizumab and were treated with as-needed IVZ (1.25 mg/0.05 mL) for 12 months. The primary outcome measure was the mean change in best corrected visual acuity (BCVA) and secondary outcome measures included mean change in central macular thickness (CMT), retinal pigment epithelial detachment (RPED) heights, longest treatment free interval, presence of subretinal fluid (SRF) and intraretinal fluid (IRF) and adverse events...
June 8, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28596285/vitreomacular-adhesion-or-vitreomacular-traction-may-affect-antivascular-endothelium-growth-factor-treatment-for-neovascular-age-related-macular-degeneration
#19
REVIEW
Ping Xie, Xinhua Zheng, Yingqing Yu, Xiaojian Ye, Zizhong Hu, Dongqing Yuan, Qinghuai Liu
OBJECTIVE: The aim of this review is to determine whether vitreomacular adhesion (VMA) or vitreomacular traction (VMT) has an influence on the outcomes of antivascular endothelium growth factor (anti-VEGF) treatment neovascular age-related macular degeneration (nAMD). METHODS: A systematic literature search was performed in Pubmed.gov, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wanfang, SinoMed and ClinicalTrials.gov up to 30 June 2016 to identify eligible studies...
June 8, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28596284/prognostic-biopsy-of-choroidal-melanoma-an-optimised-surgical-and-laboratory-approach
#20
Martina Angi, Helen Kalirai, Azzam Taktak, Rumana Hussain, Carl Groenewald, Bertil E Damato, Heinrich Heimann, Sarah E Coupland
BACKGROUND: Accurate survival prognostication for patients with uveal melanoma (UM) enables effective patient counselling and permits personalised systemic surveillance for the early detection of metastases and, in high-risk patients, enrolment in any trials of systemic adjuvant therapy. The aim of this work is to determine the success of prognostic UM tumour biopsy using an improved surgical approach and optimised sample handling workflow. METHODS: Patients with UM treated by primary radiotherapy between 2011 and 2013 and who underwent a prognostic biopsy with cytology, multiplex ligation-dependent probe amplification and/or microsatellite analysis were included...
June 8, 2017: British Journal of Ophthalmology
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