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Bone Marrow Transplantation

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https://www.readbyqxmd.com/read/27892952/dynamic-prognostic-value-of-the-revised-international-prognostic-scoring-system-following-pretransplant-hypomethylating-treatment-in-myelodysplastic-syndrome
#1
S-A Yahng, Y-W Jeon, J-H Yoon, S-H Shin, S-E Lee, Y-S Choi, D-Y Kim, J-H Lee, B-S Cho, K-S Eom, S Lee, C-K Min, H-J Kim, J-W Lee, K-H Lee, W-S Min, J-H Lee, Y-J Kim
This study aimed to analyze the use of the revised International Prognostic Scoring System (IPSS-R) assessed after hypomethylating treatment (HMT) for patients with myelodysplastic syndrome (MDS) undergoing an allogeneic stem cell transplantation (SCT). Among 115 patients who received pre-SCT HMT, comparison analysis of the prognostic values between the IPSS-R at the time of HMT (IPSS-R@HMT) and at the time of SCT after HMT (IPSS-R@SCT) showed a significantly higher predictive power for overall survival (OS) of the latter...
November 28, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27892951/comparison-of-three-or-fewer-high-dose-chemotherapy-cycles-as-salvage-treatment-in-germ-cell-tumors-in-first-relapse
#2
F Gössi, M Spahn, M Zweifel, S Panagiotis, A Mischo, F Stenner, U Hess, D Berthold, M Bargetzi, J Schardt, T Pabst
No abstract text is available yet for this article.
November 28, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27892950/pd-1-checkpoint-blockade-in-patients-with-relapsed-aml-after-allogeneic-stem-cell-transplantation
#3
J C Albring, S Inselmann, T Sauer, C Schliemann, B Altvater, S Kailayangiri, C Rössig, W Hartmann, J R Knorrenschild, K Sohlbach, C Groth, M Lohoff, A Neubauer, W E Berdel, A Burchert, M Stelljes
No abstract text is available yet for this article.
November 28, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27892949/the-ebmt-eln-working-group-recommendations-on-the-prophylaxis-and-treatment-of-gvhd-a-change-control-analysis
#4
T Ruutu, A Gratwohl, D Niederwieser, T de Witte, S van der Werf, A van Biezen, M Mohty, N Kröger, A Rambaldi, E McGrath, A Sureda, G Basak, H Greinix, R F Duarte
In 2013, recommendations for a standardized practice in the prophylaxis and treatment of GvHD were adopted and published by the European Society for Blood and Marrow Transplantation and the European LeukemiaNet. One year later, all 341 European Society for Blood and Marrow Transplantation centres performing allogeneic haematopoietic stem cell transplantation were contacted for a change-control analysis and asked to fill in a questionnaire; 111 centres (33%) responded. Of these, 83% had been aware of the recommendations...
November 28, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27892948/long-term-outcomes-after-thiotepa-based-high-dose-therapy-hdt-and-autologous-hematopoietic-cell-transplantation-auto-hct-in-non-hodgkin-lymphoma-nhl
#5
N Shah, S Rauenzahn, L Veltri, S Wen, M Craig, M Hamadani, A S Kanate, A Cumpston
No abstract text is available yet for this article.
November 28, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27892947/danaparoid-reduces-the-incidence-of-hematopoietic-stem-cell-transplantation-associated-thrombotic-microangiopathy
#6
S Machida, M Onizuka, M Toyosaki, Y Aoyama, H Kawai, J Amaki, R Hara, A Ichiki, Y Ogawa, H Kawada, K Ando
No abstract text is available yet for this article.
November 28, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27892946/first-line-escalated-beacopp-does-not-hinder-stem-cell-collection-and-transplantation-strategy-in-patients-with-relapsed-refractory-hodgkin-s-lymphoma
#7
D Ghez, C Fortpied, N Mounier, P Carde, A Perrot, H Khaled, S Amorim, S Ramadan, F L Bras, M Erlanson, C Herbaux, J-P Marolleau, E Nicolas-Virelezier, O Casasnovas, A Stamatoullas-Bastard, C Fermé
No abstract text is available yet for this article.
November 28, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27892945/therapy-of-pediatric-all-relapsing-after-allogeneic-transplant-how-to-make-progress-with-limited-patient-numbers
#8
M Bierings
No abstract text is available yet for this article.
November 28, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27892944/veno-occlusive-disease-sinusoidal-obstruction-syndrome-after-haematopoietic-stem-cell-transplantation-middle-east-north-africa-regional-consensus-on-prevention-diagnosis-and-management
#9
A H Al Jefri, H Abujazar, A Al-Ahmari, A Al Rawas, Z Al Zahrani, A Alhejazi, M A Bekadja, A Ibrahim, M Lahoucine, S Ousia, A Bazarbachi
Veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) of the liver is a serious, early complication of haematopoietic stem cell transplantation (HSCT), severe and very severe forms of which are associated with a high mortality rate. A wide variety of patient, disease and treatment-related risk factors for VOD/SOS have been identified. Several bodies have published recommendations for the diagnosis, prevention and management of VOD/SOS following HSCT. A group of regional experts have developed a consensus statement on the diagnosis, prevention and management of VOD/SOS in the Middle East and North Africa region to help in the management of HSCT patients in the region...
November 28, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27869812/low-day-100-serum-epidermal-growth-factor-levels-are-associated-with-acute-gvhd-after-allogeneic-hematopoietic-cell-transplantation
#10
F He, M R Verneris, S Cooley, B R Blazar, M L MacMillan, L F Newell, A Panoskaltsis-Mortari, T DeFor, D J Weisdorf, S G Holtan
No abstract text is available yet for this article.
November 21, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27869811/diffuse-large-b-cell-lymphoma-the-challenge-of-relapse-after-an-autologous-stem-cell-transplant
#11
S P Robinson
No abstract text is available yet for this article.
November 21, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27869810/hematopoietic-stem-cell-transplantation-in-fancj-brip1-fanconi-anemia
#12
A Alsultan, M Essa, R Alsudairy
No abstract text is available yet for this article.
November 21, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27869809/absence-of-spontaneous-response-improvement-beyond-day-100-after-autologous-stem-cell-transplantation-in-multiple-myeloma
#13
C Fernández de Larrea, J Dávila, I Isola, E M Ocio, L Rosiñol, R García-Sanz, M T Cibeira, N Tovar, M Rovira, M V Mateos, J S Miguel, J Bladé
The response evaluation after autologous stem-cell transplantation (ASCT) is usually performed at day +100 in patients with multiple myeloma (MM). A recent report suggests that improvement in the response can be observed beyond day +100. The aim of the present study has been to evaluate the rate of improved response and outcome beyond day +100 after ASCT, with and without maintenance therapy. One hundred and forty-four patients who underwent single ASCT with chemosensitive disease and achieved less than CR at day 100 post ASCT were evaluated...
November 21, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27869808/low-dose-thymoglobulin-as-second-line-treatment-for-steroid-resistant-acute-gvhd-an-analysis-of-the-jshct
#14
M Murata, K Ikegame, Y Morishita, H Ogawa, K Kaida, H Nakamae, T Ikeda, T Nishida, M Inoue, T Eto, K Kubo, T Sakura, T Mori, N Uchida, T Ashida, Y Matsuhashi, Y Miyazaki, T Ichinohe, Y Atsuta, T Teshima
A nationwide retrospective study for the clinical outcomes of 99 patients who had received thymoglobulin at a median total dose of 2.5 mg/kg (range, 0.5-18.5 mg/kg) as a second-line treatment for steroid-resistant acute GvHD was conducted. Of the 92 evaluable patients, improvement (complete or partial response) was observed in 55 patients (60%). Multivariate analysis demonstrated that male sex and grade III and IV acute GvHD were associated with a lower improvement rate, whereas thymoglobulin dose (<2...
November 21, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27869807/a-proposed-biology-and-biomarker-based-algorithm-for-management-of-acute-gvhd
#15
A M Ali, J F DiPersio, M A Schroeder
No abstract text is available yet for this article.
November 21, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27869806/preliminary-efficacy-of-a-brief-family-intervention-to-prevent-declining-quality-of-life-secondary-to-parental-bone-marrow-transplantation
#16
B L Fife, D M Von Ah, M L Spath, M T Weaver, Z Yang, T Stump, S Farag
The primary purpose of this research was to develop and evaluate the efficacy and feasibility of a brief, cost-effective family-focused intervention to promote adaptive coping and quality of life throughout a parent's bone marrow transplantation (BMT). Targeted outcomes were cohesion, decreased use of avoidance coping, open communication and effective management of emotional distress. Participants included an intervention group of 31 families and 29 families in a control group who received usual care. Each family included the BMT recipient, a partner/caregiver and children 10-18 years old...
November 21, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27841861/aggressive-skin-cancer-in-chronic-gvhd-after-allogeneic-hematopoietic-cell-transplantation
#17
J S Lehman, C L Baum, E Moore, D Price, S Toosi, S K Hashmi
No abstract text is available yet for this article.
November 14, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27841860/medication-nonadherence-to-immunosuppressants-after-adult-allogeneic-haematopoietic-stem-cell-transplantation-a-multicentre-cross-sectional-study
#18
B Gresch, M Kirsch, K Fierz, J P Halter, G Nair, K Denhaerynck, S De Geest
No abstract text is available yet for this article.
November 14, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27841859/anti-muellerian-hormone-amh-as-only-possible-marker-in-the-assessment-of-ovarian-function-and-reserve-after-hematopoietic-stem-cell-transplantation-hsct-in-prepubertal-girls-young-females-with-composed-hypogonadism-and-females-receiving-hormonal-replacement
#19
https://www.readbyqxmd.com/read/27841858/efficacy-of-host-dendritic-cell-vaccinations-with-or-without-minor-histocompatibility-antigen-loading-combined-with-donor-lymphocyte-infusion-in-multiple-myeloma-patients
#20
R Oostvogels, E Kneppers, M C Minnema, R C Doorn, L E Franssen, T Aarts, M E Emmelot, E Spierings, I Slaper-Cortenbach, K Westinga, E Goulmy, H M Lokhorst, T Mutis
Donor lymphocyte infusions (DLI) can induce durable remissions in multiple myeloma (MM) patients, but this occurs rather infrequently. As the graft-versus-tumor (GvT) effect of DLI depends on the presence of host-dendritic cells (DCs), we tested in a phase I/II trial whether the efficacy of DLI could be improved by simultaneous vaccination with host-DCs. We also analyzed the possibility of further improving the GvT effect by loading the DCs with peptides of mismatched hematopoietic cell-specific minor histocompatibility antigens (mHags)...
November 14, 2016: Bone Marrow Transplantation
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