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Bone Marrow Transplantation

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https://www.readbyqxmd.com/read/30451965/the-44-th-annual-meeting-of-the-european-society-for-blood-and-marrow-transplantation-physicians-poster-sessions
#1
(no author information available yet)
No abstract text is available yet for this article.
November 19, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30446742/indications-for-allogeneic-hematopoietic-cell-transplantation-for-adults-with-philadelphia-chromosome-negative-acute-lymphoblastic-leukemia-in-first-complete-remission-all-about-mrd
#2
Ibrahim Aldoss, Vinod Pullarkat
No abstract text is available yet for this article.
November 16, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30446741/low-dose-anti-thymocyte-globulin-plus-low-dose-posttransplant-cyclophosphamide-as-graft-versus-host-disease-prophylaxis-in-haploidentical-peripheral-blood-stem-cell-transplantation-combined-with-unrelated-cord-blood-for-patients-with-hematologic-malignancies
#3
Jun Yang, Jieling Jiang, Yu Cai, Su Li, Liping Wan, Jun Zhu, Huixia Liu, Shan Shao, Haitao Bai, Chun Wang, Xianmin Song
Nowadays, the most wildly used regimens for graft-versus-host disease (GvHD) prophylaxis in haplo-hematopoietic stem cell transplantation (Haplo-HSCT) are based on in vivo T-cell depletion (TCD) with anti-thymocyte globulin (ATG) or posttransplant cyclophosphamide (PTCy). To improve the efficiency of GvHD prophylaxis in haploidentical peripheral blood stem cell transplantation combined with unrelated cord blood (Haplo-PBSCT-Cord), a novel regimen, which is composed of low dose of ATG (5 mg/kg) and low-dose PTCy (50 mg/kg) for GvHD prophylaxis, was evaluated in a prospective phase II clinical trial (Clinicaltrials...
November 16, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30446740/primary-plasma-cell-leukemia-autologous-stem-cell-transplant-in-an-era-of-novel-induction-drugs
#4
Lohith Gowda, Mithun Shah, Ifra Badar, Qaiser Bashir, Nina Shah, Krina Patel, Rashmi Kanagal-Shamanna, Rohtesh Mehta, Donna M Weber, Hans C Lee, Elisabet E Manasanch, Abdul Shah, Sheeba K Thomas, Simrit Parmar, Yago Nieto, Robert Z Orlowski, Richard Champlin, Muzaffar H Qazilbash
Primary plasma cell leukemia (pPCL) is a rare and aggressive variant of multiple myeloma (MM) with poor long-term survival after cytotoxic chemotherapy. Many novel drugs have revolutionized the treatment algorithms for MM. The impact of targeted therapy, both pre- and post-autologous stem cell transplant (auto-HCT) remains an area of ongoing interest. In this study, we report outcomes post auto-HCT for pPCL and the impact of maintenance therapy posttransplant with novel agents.
November 16, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30446739/antithymocyte-globulin-for-graft-versus-host-disease-prophylaxis-an-updated-systematic-review-and-meta-analysis
#5
Ambuj Kumar, Tea Reljic, Mehdi Hamadani, Mohamad Mohty, Mohamed A Kharfan-Dabaja
Graft-versus-host disease (GVHD) remains a limiting factor for successful allogeneic hematopoietic cell transplantation (allo-HCT). Conflicting data exist on the benefit of ATG on post-transplant survival. We performed a systematic review of randomized controlled trials (RCTs) to assess benefits and harms of thymoglobulin and Fresenius (re-branded as Grafalon) ATG formulations in patients undergoing allo-HCT for a variety of hematologic malignancies and bone marrow failure syndromes. A comprehensive search of MEDLINE, EMBASE, and Cochrane Library was performed...
November 16, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30429538/antioxidants-good-bad-or-indifferent
#6
EDITORIAL
Shaun McCann
No abstract text is available yet for this article.
November 14, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30420665/the-44-th-annual-meeting-of-the-european-society-for-blood-and-marrow-transplantation-physicians-poster-sessions
#7
(no author information available yet)
No abstract text is available yet for this article.
November 12, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30413812/transplant-associated-thrombotic-microangiopathy-is-the-treatment-more-expensive-than-the-disease
#8
LETTER
John L Vaughn, Qiuhong Zhao, Narendranath Epperla, Marcin Puto, Julianna Roddy, Patrick Elder, William Blum, Rebecca Klisovic, Samantha Jaglowski, Sam Penza, Basem William, Leslie Andritsos, Jonathan E Brammer, Craig Hofmeister, Yvonne Efebera, Don Benson, Steven Devine, Spero Cataland, Sumithira Vasu
No abstract text is available yet for this article.
November 9, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30413811/allogeneic-stem-cell-transplantation-for-patients-with-relapsed-or-refractory-t-cell-lymphoma-efficacy-of-lymphoma-directed-conditioning-against-advanced-disease
#9
Gerald Wulf, Justin Hasenkamp, Wolfram Jung, Christian Wilhelm, Gerhard Held, Maike Nickelsen, Andreas Leha, Michael Pfreundschuh, Norbert Schmitz, Lorenz Trümper, Bertram Glass
Salvage chemotherapy induces disease remissions in patients with relapsed or refractory (r/r) T-cell lymphomas, but fails to provide lasting tumor control. We analyzed the outcome after peripheral blood stem and bone marrow transplantation (PBSCT, n = 80; BMT, n = 4) from matched related (MRD, n = 22) or matched and unmatched unrelated donors (MUD and MMD, n = 53 and n = 9, respectively) following conditioning with fludarabine, busulfan, and cyclophosphamide (FBC) for 84 consecutive patients with r/r T-cell malignancies...
November 9, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30413810/pneumocystis-jirovecii-pneumonia-prophylaxis-in-allogeneic-hematopoietic-cell-transplant-recipients-can-we-always-follow-the-guidelines
#10
Rabah Redjoul, Christine Robin, Francoise Foulet, Mathieu Leclerc, Florence Beckerich, Ludovic Cabanne, Roberta di Blasi, Cécile Pautas, Andrea Toma, Francoise Botterel, Sébastien Maury, Catherine Cordonnier
Pneumocystis jirovecii pneumonia (PCP) is a life-threatening disease in allogeneic hematopoietic cell transplantation (HCT) recipients. Trimethoprim-sulfamethoxazole (TMP-SMX) is the preferred prophylaxis but has significant toxicity. We assessed 139 consecutive HCT patients for PCP prophylaxis in our center. According to our procedures, TMP-SMX should be given as first-line prophylaxis from engraftment. In case of intolerance, atovaquone (ATO) or aerosolized pentamidine may be given. Thirteen (9.3%) patients did not receive prophylaxis because they early died...
November 9, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30413809/relationship-of-post-transplant-thymopoiesis-with-cd4-foxp3-regulatory-t-cell-recovery-associated-with-freedom-from-chronic-graft-versus-host-disease
#11
LETTER
Erin M Trovillion, Nicholas J Gloude, Eric J Anderson, Gerald P Morris
No abstract text is available yet for this article.
November 9, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30410083/beac-carmustine-etoposide-cytarabine-and-cyclophosphamide-in-autologous-hematopoietic-cell-transplantation-a-safe-and-effective-alternative-conditioning-regimen-for-hodgkin-and-non-hodgkin-lymphoma
#12
LETTER
Ioanna Sakellari, Eleni Gavriilaki, Stella Bouziana, Varnavas Constantinou, Despina Mallouri, Anna Vardi, Anastasia Marvaki, Ioannis Batsis, Damianos Sotiropoulos, Achilles Anagnostopoulos
No abstract text is available yet for this article.
November 8, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30410082/post-transplant-immunotherapy-with-wt1-specific-ctls-for-high-risk-acute-myelogenous-leukemia-a-prospective-clinical-phase-i-ii-trial
#13
LETTER
Hee-Je Kim, Hyun-Jung Sohn, Jung-A Hong, Hyun-Joo Lee, Dae-Hee Sohn, Chang-Ae Shin, Hyun-Il Cho, Woo-Sung Min, Tai-Gyu Kim
No abstract text is available yet for this article.
November 8, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30401971/chirality-and-wine
#14
EDITORIAL
Shaun McCann
No abstract text is available yet for this article.
November 6, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30401970/post-transplantation-cyclophosphamide-based-haploidentical-versus-atg-based-unrelated-donor-allogeneic-stem-cell-transplantation-for-patients-younger-than-60-years-with-hematological-malignancies-a-single-center-experience-of-209-patients
#15
Thomas Pagliardini, Samia Harbi, Sabine Fürst, Luca Castagna, Faezeh Legrand, Catherine Faucher, Angela Granata, Pierre-Jean Weiller, Boris Calmels, Claude Lemarie, Christian Chabannon, Reda Bouabdallah, Djamel Mokart, Norbert Vey, Didier Blaise, Raynier Devillier
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is limited by availability of HLA-matched sibling donors (MSDs). The alternative use of unrelated donors (UDs) is currently challenged by haploidentical-related donors (HRDs). We retrospectively analyzed 209 consecutive patients younger than 60 years undergoing allo-HSCT from UDs (n = 128) or HRDs (n = 81). Cumulative incidences of grade 3-4 acute (17 vs. 2%, p = 0.003) and 2-year moderate and severe chronic (20 vs. 2%, p < 0...
November 6, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30401969/late-relapse-after-stopping-sorafenib-in-allogeneic-hematopoietic-stem-cell-transplant-recipients
#16
LETTER
S Gerull, A Tschan-Plessl, R Mathew, G Nair, J R Passweg, J P Halter
No abstract text is available yet for this article.
November 6, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30401968/no-post-transplant-pure-red-cell-aplasia-development-in-106-major-abo-incompatible-cord-blood-transplantation
#17
LETTER
Sachie Wada, Yuki Asano-Mori, Hisashi Yamamoto, Mitsuhiro Yuasa, Kosei Kageyama, Daisuke Kaji, Aya Nishida, Kazuya Ishiwata, Shinsuke Takagi, Go Yamamoto, Naoyuki Uchida, Akiko Yoneyama, Shigeyoshi Makino, Shuichi Taniguchi
No abstract text is available yet for this article.
November 6, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30401967/vitamin-d-is-it-important-in-haematopoietic-stem-cell-transplantation-a-review
#18
REVIEW
Jose Ros-Soto, Chloe Anthias, Alejandro Madrigal, John A Snowden
Vitamin D has effects on several body systems, from well-established role in bone metabolism to emerging effects on the immune system. Increasing evidence supports an immunomodulatory effect including inhibition of the pro-inflammatory lymphocyte subsets while enhancing their anti-inflammatory counterpart, in favour of a more tolerogenic status. Vitamin D deficiency is increasingly recognised in association with autoimmune and inflammatory diseases, also with evidence from the field of asthma where vitamin D supplementation may overcome steroid resistance...
November 6, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30401966/breakthrough-cytomegalovirus-pneumonia-in-hematopoietic-stem-cell-transplant-recipient-on-letermovir-prophylaxis
#19
LETTER
Bettina M Knoll, Karen Seiter, Adrienne Phillips, Rosemary Soave
No abstract text is available yet for this article.
November 6, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/30401965/effects-of-hla-mismatch-on-cytomegalovirus-reactivation-in-cord-blood-transplantation
#20
Hisayuki Yokoyama, Junya Kanda, Shunichi Kato, Eisei Kondo, Yoshinobu Maeda, Hiroo Saji, Satoshi Takahashi, Makoto Onizuka, Yasushi Onishi, Yukiyasu Ozawa, Heiwa Kanamori, Jun Ishikawa, Yuju Ohno, Tatsuo Ichinohe, Minoko Takanashi, Koji Kato, Yoshiko Atsuta, Yoshinobu Kanda
Although human leukocyte antigen (HLA) mismatch is often thought to be associated with a high incidence of cytomegalovirus (CMV) reactivation, it is not clear whether this process is mediated by HLA mismatch or other factors, such as acute graft-versus-host disease (aGVHD). Here we focused on cord blood transplantation (CBT) and examined the effects of HLA mismatch on the incidence of CMV reactivation while minimizing the effects of aGVHD. In a multivariate analysis considering aGVHD as a time-dependent covariate, a significant effect on the incidence of CMV reactivation was noted for HLA disparity (hazard ratio [HR]: 0...
November 6, 2018: Bone Marrow Transplantation
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