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Bone Marrow Transplantation

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https://www.readbyqxmd.com/read/28737776/therapeutic-salivary-monitoring-of-iv-busulfan-in-patients-undergoing-hematopoietic-stem-cell-transplantation-a-pilot-study
#1
L M Bezinelli, F P Eduardo, D L C de Carvalho, C E Dos Santos Ferreira, E V de Almeida, L R Sanches, I Esteves, P V Campregher, N Hamerschlak, L Corrêa
Individual therapeutic monitoring of busulfan (BU) minimizes its toxicity and improves the therapeutic outcomes during hematopoietic stem cell transplantation (HSCT). For individual dose adjustment, several blood collections are performed that are uncomfortable for patients. The aim of this pilot study was to validate a laboratory method for quantification of BU in saliva and to present the results obtained using this protocol in HSCT patients. We performed analyses of selectivity, precision and accuracy of saliva with standard concentrations of BU using ultra-high-performance liquid chromatography with diode array detection...
July 24, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28737775/fertility-preservation-issues-in-pediatric-hematopoietic-stem-cell-transplantation-practical-approaches-from-the-consensus-of-the-pediatric-diseases-working-party-of-the-ebmt-and-the-international-bfm-study-group
#2
A Balduzzi, J-H Dalle, K Jahnukainen, M von Wolff, G Lucchini, M Ifversen, K T Macklon, C Poirot, T Diesch, A Jarisch, D Bresters, I Yaniv, B Gibson, A M Willasch, R Fadini, L Ferrari, A Lawitschka, A Ahler, N Sänger, S Corbacioglu, M Ansari, R Moffat, A Dalissier, E Beohou, P Sedlacek, A Lankester, C D De Heredia Rubio, K Vettenranta, J Wachowiak, A Yesilipek, E Trigoso, T Klingebiel, C Peters, P Bader
Fertility preservation is an urgent challenge in the transplant setting. A panel of transplanters and fertility specialists within the Pediatric Diseases Working Party of the European Society for Blood and Marrow Transplantation (EBMT) and the International BFM Study Group provides specific guidelines. Patients and families should be informed of possible gender- and age-specific cryopreservation strategies that should be tailored according to the underlying disease, clinical condition and previous exposure to chemotherapy...
July 24, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28737774/outcomes-of-salvage-autologous-stem-cell-transplantation-for-multiple-myeloma-with-cytopenias-and-exposure-to-novel-agents
#3
D Tremblay, G Lancman, E Moshier, N Bar, S Jagannath, A Chari
No abstract text is available yet for this article.
July 24, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28737773/the-incidence-of-atrial-fibrillation-among-patients-with-al-amyloidosis-undergoing-high-dose-melphalan-and-stem-cell-transplantation-experience-at-a-single-institution
#4
M Arun, D Brauneis, G Doros, A C Shelton, J M Sloan, K Quillen, F L Ruberg, V Sanchorawala, C Varga
No abstract text is available yet for this article.
July 24, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28714948/early-hepatitis-e-infection-in-an-unrelated-hematopoietic-progenitor-stem-cell-donor
#5
D O'Donghaile, N O'Flaherty, S Field
No abstract text is available yet for this article.
July 17, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28714947/long-term-systolic-function-in-children-and-young-adults-after-hematopoietic-stem-cell-transplant
#6
S J Rotz, C E Dandoy, M D Taylor, S Jodele, J L Jefferies, A Lane, J A El-Bietar, A W Powell, S M Davies, T D Ryan
Congestive heart failure and subclinical left ventricular systolic dysfunction (LVSD) affect long-term survivors of hematopoietic stem cell transplant (HSCT). Echocardiographic measurements of global longitudinal and circumferential strain have shown promise in identifying subclinical LVSD in cancer survivors. We analyzed echocardiograms in 95 children and young adults with malignancies or bone marrow failure syndromes performed before HSCT and 1-6 years after HSCT. We additionally measured the biomarkers soluble suppression of tumorigenicity-2 (sST-2) and cardiac troponin-I (cTn-I) in the same children through 49 days post HSCT...
July 17, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28714946/faecal-microbiota-transplant-a-novel-biological-approach-to-extensively-drug-resistant-organism-related-non-relapse-mortality
#7
A J Innes, B H Mullish, F Fernando, G Adams, J R Marchesi, J F Apperley, E Brannigan, F Davies, J Pavlů
No abstract text is available yet for this article.
July 17, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28714945/impact-of-molecular-residual-disease-post-allografting-in-myelofibrosis-patients
#8
C Wolschke, A Badbaran, T Zabelina, M Christopeit, F Ayuk, I Triviai, A Zander, H Alchalby, U Bacher, B Fehse, N Kröger
We screened 136 patients with myelofibrosis and a median age of 58 years who underwent allogeneic stem cell transplantation (AHSCT) for molecular residual disease for JAKV617F (n=101), thrombopoietin receptor gene (MPL) (n=4) or calreticulin (CALR) (n=31) mutation in peripheral blood on day +100 and +180 after AHSCT. After a median follow-up of 78 months, the 5-year estimated overall survival was 60% (95% confidence interval (CI): 50-70%) and the cumulative incidence of relapse at 5 years was 26% (95% CI: 18-34%) for the entire study population...
July 17, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28714944/impact-of-the-presence-of-hla-1-locus-mismatch-and-the-use-of-low-dose-antithymocyte-globulin-in-unrelated-bone-marrow-transplantation
#9
K Kawamura, J Kanda, S Fuji, M Murata, K Ikegame, K Yoshioka, T Fukuda, Y Ozawa, N Uchida, K Iwato, T Sakura, M Hidaka, H Hashimoto, T Ichinohe, Y Atsuta, Y Kanda
HLA 1-locus-mismatched unrelated donors (1MMUD) have been used in allogeneic hematopoietic stem cell transplantation (allo-HCT) for patients who lack an HLA-matched donor. We retrospectively analyzed 3313 patients with acute leukemia or myelodysplastic syndrome who underwent bone marrow transplantation from an HLA allele-matched unrelated donor (MUD) or 1MMUD between 2009 and 2014. We compared the outcomes of MUD (n=2089) and 1MMUD with antithymocyte globulin (ATG) (1MM-ATG(+); n=109) with those of 1MMUD without ATG (1MM-ATG(-); n=1115)...
July 17, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28714943/dengue-encephalitis-in-allogenic-hematopoietic-stem-cell-transplantation-recipient
#10
K S N Barroso, J Kaufman, D M Brunetta, F M de Carvalho Araújo, F Barroso-Duarte
No abstract text is available yet for this article.
July 17, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28692031/cord-blood-attached-segment-is-this-a-relevant-quality-control-to-predict-a-good-hematopoietic-stem-cell-graft
#11
L Faivre, H Boucher, R Zerbib, T Domet, A Desproges, C Couzin, V Vanneaux, J Larghero, A Cras
No abstract text is available yet for this article.
July 10, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28692030/hla-mismatched-bone-marrow-transplantation-in-severe-aplastic-anemia
#12
L S Bachegowda, M V Shah, L W Veltri, A Tanase, U Popat, P Anderlini, J Chen, G Rondon, R E Champlin, S O Ciurea
No abstract text is available yet for this article.
July 10, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28692029/pre-autologous-transplantation-pet-ct-using-deauville-criteria-is-an-independent-predictor-of-progression-in-relapsed-refractory-classical-hodgkin-lymphoma
#13
M Damlaj, S Ghazi, G Syed, T Pasha, G Gmati, H Salama, O Ali, K A Abuelgasim, M Al-Zahrani, A Hejazi, A Al Askar
No abstract text is available yet for this article.
July 10, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28692028/in-search-of-the-optimal-platform-for-post-allogeneic-sct-immunotherapy-in-relapsed-multiple-myeloma-a-systematic-review
#14
REVIEW
R Oostvogels, S M U Venema, M de Witte, R Raymakers, J Kuball, N Kröger, M C Minnema
Allogeneic stem cell transplantation (allo-SCT) has the potential to induce sustained remissions in patients with multiple myeloma (MM). Currently, allo-SCT is primarily performed in high-risk MM patients, most often in the setting of early relapse after first-line therapy with autologous SCT. However, the implementation of allo-SCT for MM is jeopardized by high treatment-related mortality (TRM) rates as well as high relapse rates. In this systematic review, we aimed to identify a safe allo-SCT strategy that has optimal 1-year results regarding mortality, relapse and severe GvHD, creating opportunities for post-transplantation strategies to maintain remissions in the high-risk group of relapsed MM patients...
July 10, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28692027/jacie-accreditation-from-the-perspective-of-an-accredited-centre
#15
C Boga, I Kozanoglu
No abstract text is available yet for this article.
July 10, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28692026/association-between-single-nucleotide-polymorphisms-of-tumor-necrosis-factor-gene-and-grade-ii-iv-acute-gvhd-a-systematic-review-and-meta-analysis
#16
A Rashidi, D Weisdorf
Acute GvHD (aGvHD) complicates up to 50% of allogeneic hematopoietic cell transplants and pre-transplant estimation of its risk can guide prophylaxis, monitoring and early intervention strategies. Inspired by the role of tumor necrosis factor alpha (TNFα) in the pathogenesis of aGvHD and the inconsistency of the association studies exploring single nucleotide polymorphisms (SNPs) of the TNF gene, we conducted a systematic review and meta-analysis of the available reports using PubMed and EMBASE. Original human studies reporting on the association between recipient TNF SNPs and grade II-IV aGvHD in a format convertible to effect size and confidence interval were included...
July 10, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28692025/cerebral-adenovirus-endotheliitis-presenting-as-posterior-reversible-encephalopathy-syndrome-after-allogeneic-stem-cell-transplantation
#17
J-S Claveau, R LeBlanc, I Ahmad, J Ferreira, A-A Pistono, N Bambace, L Bernard, S Cohen, J-S Delisle, T Kiss, S Lachance, J Roy
No abstract text is available yet for this article.
July 10, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28692024/no-report-on-zika-virus-infection-in-ebmt-registry-infectious-diseases-working-party-statement
#18
J Styczynski, J Hoek, N Knelange, M Mikulska, S Cesaro, M Aljurf, L Gil
No abstract text is available yet for this article.
July 10, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28692023/trust-not-education-is-the-key-to-consent-in-hematopoietic-cell-transplant-in-response-to-d-souza-pasquini-and-spellecy
#19
C L Scanlan, C Stewart, I Kerridge
No abstract text is available yet for this article.
July 10, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28692022/gender-differences-in-physical-function-and-muscle-mass-change-in-patients-undergoing-allogeneic-hematopoietic-stem-cell-transplantation
#20
T Takekiyo, K Dozono, S Nara, Y Murayama, N Minamihama, N Nakano, A Kubota, M Tokunaga, T Miyazono, S Takeuchi, Y Takatsuka, A Utsunomiya
No abstract text is available yet for this article.
July 10, 2017: Bone Marrow Transplantation
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