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BJU International

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https://www.readbyqxmd.com/read/28516513/evaluating-an-educational-intervention-to-alleviate-distress-amongst-men-with-newly-diagnosed-prostate-cancer-and-their-partners
#1
Lindsay Hedden, Richard Wassersug, Sarah Mahovlich, Phil Pollock, Monita Sundar, Robert H Bell, Larry Goldenberg, Celestia S Higano
OBJECTIVE: To determine whether an education session alleviates distress for both patients with prostate cancer and their partners; and whether their partner's attendance at the session; and disease, treatment, and sociodemographic characteristics affect changes in distress levels. PATIENTS, SUBJECTS AND METHODS: We identified men with untreated prostate cancer at the Vancouver Prostate Centre between February 2015 and March 2016 who agreed to attend our education session...
May 17, 2017: BJU International
https://www.readbyqxmd.com/read/28502080/the-contemporary-role-of-ureterolysis-in-retroperitoneal-fibrosis-rpf-treatment-of-last-resort-or-first-intent-an-analysis-of-50-cases
#2
Tim O'Brien, Archie Fernando
OBJECTIVE: To determine the outcomes of open ureterolysis in a contemporary cohort of patients presenting with ureteric obstruction secondary to retroperitoneal fibrosis (RPF). PATIENTS AND METHODS: Prospective analysis of 50 patients undergoing open ureterolysis and omental wrap between January 2012 and January 2016 in a single centre managed by a multi-disciplinary RPF team. Minimum follow up of 1 year. Indications were: nephrostomy-dependent drainage (n=5); stent failure as evidenced by persistent hydronephrosis (n=20); severe stent symptoms (n=22); and patient choice/pre-emptive (n=3)...
May 14, 2017: BJU International
https://www.readbyqxmd.com/read/28498624/additional-benefit-of-using-a-risk-based-selection-for-prostate-biopsy-an-analysis-of-biopsy-complications-in-the-rotterdam-section-of-the-european-randomized-study-of-screening-for-prostate-cancer-erspc
#3
Peter K F Chiu, Arnout R Alberts, Lionne D F Venderbos, Chris H Bangma, Monique J Roobol
OBJECTIVE: To investigate biopsy complications and hospital admissions that could be reduced by the use of ERSPC risk calculators (RC). MATERIALS AND METHODS: All biopsies in the Rotterdam section of the ERSPC from 1993 to 2015 were included. Biopsy complications and hospital admission data were prospectively recorded in questionnaires that were completed 2 weeks after biopsy. The ERSPC RC3 and RC4 were applied to men attending the first and subsequent rounds of screening, respectively...
May 12, 2017: BJU International
https://www.readbyqxmd.com/read/28481440/prognostic-utility-of-biopsy-derived-cell-cycle-progression-score-in-patients-with-nccn-low-risk-prostate-cancer-undergoing-radical-prostatectomy-implications-for-treatment-guidance
#4
Jeffrey T Tosoian, Meera R Chappidi, Jay T Bishoff, Stephen J Freedland, Julia Reid, Michael Brawer, Steven Stone, Thorsten Schlomm, Ashley E Ross
OBJECTIVES: To determine the prognostic utility of the Cell Cycle Progression (CCP) score in men with National Comprehensive Cancer Network (NCCN) low-risk prostate cancer who underwent radical prostatectomy (RP). PATIENTS AND METHODS: Patients who underwent RP for Gleason score ≤6 prostate cancer at three institutions (Martini Clinic [MC], Durham Veterans Affairs Medical Center [DVA], and Intermountain Healthcare [IHC]) were identified. The CCP score was obtained from diagnostic (DVA, IHC) or simulated biopsies (MC)...
May 8, 2017: BJU International
https://www.readbyqxmd.com/read/28480994/association-of-human-development-index-with-global-bladder-kidney-prostate-and-testis-cancer-incidence-and-mortality
#5
Alyssa K Greiman, James S Rosoff, Sandip M Prasad
OBJECTIVES: To describe contemporary worldwide age-standardized incidence and mortality rates for bladder, kidney, prostate and testis cancer and their association with development. MATERIALS AND METHODS: We obtained gender-specific, age-standardized incidence and mortality rates for 184 countries and 16 major world regions from the GLOBOCAN 2012 database. We compared the mortality-to-incidence ratios (MIRs) at national and regional levels in males and females, and assessed the association with socio-economic development using the 2014 United Nations Human Development Index (HDI)...
May 8, 2017: BJU International
https://www.readbyqxmd.com/read/28471484/tweet-this-how-advocacy-for-breast-and-prostate-cancers-stacks-up-on-social-media
#6
LETTER
Stacy Loeb, Brian Stork, Heather T Gold, Natasha K Stout, Danil V Makarov, Christopher Weight, Hendrik Borgmann
Despite the large burden of disease for both breast and prostate cancer, breast cancer receives substantially more federal funding and little is known about the extent to which advocacy in social media differs between them. We aimed to perform a comprehensive comparison of Twitter activity related to prostate and breast cancer over the past 5 years (1/11-1/16) using the Symplur Signals analytics platform. Overall there were 2,518,250 tweets from 800,833 users about breast cancer and 389,696 tweets from 106,507 users about prostate cancer over the 5-year period between 2012-2017 demonstrating a 7-fold higher activity for breast cancer...
May 4, 2017: BJU International
https://www.readbyqxmd.com/read/28464554/does-the-training-of-fellows-affect-perioperative-outcomes-of-robotic-partial-nephrectomy
#7
Zine-Eddine Khene, Benoit Peyronnet, Elise Bosquet, Benjamin Pradère, Corentin Robert, Tarek Fardoun, Solène-Florence Kammerer-Jacquet, Grégory Verhoest, Nathalie Rioux-Leclercq, Romain Mathieu, Karim Bensalah
OBJECTIVE: To evaluate the impact of fellows' involvement on robot-assisted partial nephrectomy (RAPN) perioperative outcomes. MATERIALS AND METHODS: We analysed 216 patients who underwent RAPN for a small renal tumour. We stratified our cohort into two groups according to the involvement of a fellow surgeon during the procedure: expert surgeon operating alone (expert group) or fellow operating under the supervision of the expert surgeon (fellow group). Perioperative data were compared between the two groups...
May 2, 2017: BJU International
https://www.readbyqxmd.com/read/28464520/reduced-estimated-glomerular-filtration-rate-egfr-60-ml-min-at-first-transurethral-resection-of-bladder-tumor-is-a-significant-predictor-of-subsequent-recurrence-and-progression
#8
Michael L Blute, Victor Kucherov, Timothy J Rushmer, Shivashankar Damodaran, Fangfang Shi, E Jason Abel, David F Jarrard, Kyle A Richards, Edward M Messing, Tracy M Downs
INTRODUCTION: To evaluate if moderate CKD (eGFR <60 ml/min) is associated with high rates of NMIBC recurrence or progression. PATIENTS AND METHODS: A multi-institutional database identified patients with serum creatinine values prior to first TURBT. CKD-epidemiology collaboration formula calculated patient estimated glomerular filtration rate (eGFR). Cox proportional hazards models evaluated associations with recurrence-free (RFS) and progression-free survival (PFS)...
May 2, 2017: BJU International
https://www.readbyqxmd.com/read/28464446/unification-of-favorable-intermediate-unfavorable-intermediate-and-very-high-risk-stratification-criteria-for-prostate-cancer
#9
Zachary S Zumsteg, Michael J Zelefsky, Kaitlin M Woo, Daniel E Spratt, Marisa A Kollmeier, Sean McBride, Xin Pei, Howard M Sandler, Zhigang Zhang
OBJECTIVE: To improve on the existing risk-stratification systems. PATIENTS AND METHODS: This was a retrospective investigation including 2248 patients undergoing dose-escalated external beam radiotherapy (EBRT) at a single institution. We separated National Comprehensive Cancer Network (NCCN) intermediate-risk prostate cancer into favorable and unfavorable groups based on primary Gleason pattern, percentage of positive biopsy cores (PPBC), and number of NCCN intermediate-risk factors...
May 2, 2017: BJU International
https://www.readbyqxmd.com/read/28453896/clinical-and-patient-reported-outcomes-of-spare-a-randomised-feasibility-study-of-selective-bladder-preservation-versus-radical-cystectomy
#10
R A Huddart, A Birtle, L Maynard, M Beresford, J Blazeby, J Donovan, J D Kelly, T Kirkbank, D B McLaren, G Mead, C Moynihan, R Persad, C Scrase, R Lewis, E Hall
OBJECTIVES: To test the feasibility of a randomised trial in muscle invasive bladder cancer (MIBC) and compare outcomes in patients who receive neoadjuvant chemotherapy followed by radical cystectomy or selective bladder preservation, where definitive treatment (cystectomy or radiotherapy) is determined by response to chemotherapy. PATIENTS AND METHODS: SPARE is a multicentre randomised controlled trial comparing radical cystectomy and selective bladder preservation in patients with MIBC staged T2-3 N0 M0, fit for both treatment strategies and receiving three cycles of neoadjuvant chemotherapy...
April 28, 2017: BJU International
https://www.readbyqxmd.com/read/28452170/trends-in-the-surgical-management-of-stage-1-renal-cell-carcinoma-findings-from-a-population-based-study
#11
V White, D J T Marco, D Bolton, I D Davis, M Jefford, D Hill, H M Prince, J L Millar, I M Winship, M Coory, G G Giles
OBJECTIVES: To determine whether use of nephron sparing surgery (NSS) for treatment of stage 1 renal cell carcinomas changed between 2009 and end 2013 in Australia. PATIENTS AND METHODS: All adult cases of renal cell carcinoma diagnosed in 2009, 2012, and 2013 were identified through the population-based Victorian Cancer Registry. For each identified patient, trained data-abstractors attended treating hospitals or clinician rooms to extract tumour and treatment data through medical record review...
April 28, 2017: BJU International
https://www.readbyqxmd.com/read/28440053/who-is-at-risk-of-death-from-nephrectomy-an-analysis-of-thirty-day-mortality-after-21-380-nephrectomies-in-3-years-of-the-british-association-of-urological-surgeons-baus-national-nephrectomy-audit
#12
Archie Fernando, Sarah Fowler, Mieke Van Hemelrijck, Tim O'Brien
OBJECTIVE: To ascertain contemporary overall and differential thirty-day mortality (TDM) rates after all types of nephrectomy in the UK, and to identify potential new risk factors for death. PATIENTS AND METHODS: We conducted a retrospective analysis of the 110 deaths that occurred within 30 days of surgery out of the total of 21 380 nephrectomies performed, and calculated the odds ratio (OR) and 95% confidence interval (CI) for TDM based on peri-operative characteristics...
April 24, 2017: BJU International
https://www.readbyqxmd.com/read/28437038/impact-of-preoperative-risk-on-metastatic-progression-and-cancer-specific-death-in-patients-with-adverse-pathology-at-radical-prostatectomy
#13
Katharina Boehm, Sami-Ramzi Leyh-Bannurah, Clemens Rosenbaum, Laurenz S Brandi, Lars Budäus, Markus Graefen, Hartwig Huland, Axel Haferkamp, Derya Tilki
OBJECTIVE: To evaluate the impact of preoperative risk category on metastatic disease (MetD) and prostate cancer mortality (CSM) in prostate cancer (PCa) patients with adverse pathology at radical prostatectomy (RP). PATIENTS AND METHODS: The records of 6943 patients who underwent radical prostatectomy (RP) in a European tertiary-center were analysed. Biochemical recurrence (BCR), MetD and CSM were assessed for patients with adverse pathology at RP and stratified according to preoperative low- vs...
April 24, 2017: BJU International
https://www.readbyqxmd.com/read/28437034/robot-assisted-versus-open-radical-prostatectomy-the-day-after
#14
LETTER
Vincenzo Ficarra, Giacomo Novara, Prokar Dasgupta
Contrary to the available systematic reviews of non-randomized comparative studies, the recent Australian RCT demonstrated that robot-assisted (RARP) and retropubic radical prostatectomy (RRP) yield similar functional outcomes at 12 weeks follow-up. Conversely, the same trial confirmed that RARP has been associated with lower estimated blood loss (EBL), better pain control and equivalent complication rate in comparison with RRP. The Authors discussed some critical aspects influencing the interpretation of the results of the Royal Brisbane & Women's Hospital (RBWH) trial and the implications for patients, urologists and health system providers...
April 24, 2017: BJU International
https://www.readbyqxmd.com/read/28437031/patient-reported-outcome-pro-questionnaires-for-men-who-have-radical-surgery-for-prostate-cancer-a-conceptual-review-of-existing-instruments
#15
REVIEW
Evangelia Protopapa, Jan van der Meulen, Caroline M Moore, Sarah C Smith
OBJECTIVES: To critically review conceptual frameworks for available patient reported outcome (PRO) questionnaires in men having radical prostatectomy; psychometrically evaluate each questionnaire; identify whether each is appropriate for use at the level of the individual patient. MATERIALS AND METHODS: We searched PubMed, the Reports and Publications database of the University of Oxford Patient Reported Outcomes Measurement Group and the website of the International Consortium for Health Outcomes Measurement (ICHOM) for psychometric reviews of prostate cancer specific PRO questionnaires...
April 24, 2017: BJU International
https://www.readbyqxmd.com/read/28437029/the-men-s-eating-and-living-meal-study-calgb-70807-alliance-recruitment-feasibility-and-baseline-demographics-of-a-randomized-trial-of-diet-in-men-on-active-surveillance-for-prostate-cancer
#16
J Kellogg Parsons, John P Pierce, James Mohler, Electra Paskett, Sin-Ho Jung, Michael J Morris, Eric Small, Olwen Hahn, Peter Humphrey, John Taylor, James Marshall
OBJECTIVE: To assess the feasibility of performing national, randomized trials of dietary interventions for localized prostate cancer. METHODS: The Men's Eating and Living (MEAL) Study (CALGB 70807 [Alliance]) is a phase 3 clinical trial testing the efficacy of a high-vegetable diet to prevent progression in prostate cancer patients on active surveillance. Participants were randomized to a validated diet counseling intervention or a control condition. Chi-Square and Kruskal Wallis analyses were used to assess between-group differences at baseline...
April 24, 2017: BJU International
https://www.readbyqxmd.com/read/28437028/esut-educational-video-on-fluoroscopic-guided-puncture-in-pcnl-all-techniques-step-by-step
#17
Iason Kyriazis, Evangelos Liatsikos, Odysseas Sopilidis, Panagiotis Kallidonis, Andreas Skolarikos
OBJECTIVE: Kidney puncture during percutaneous nephrolithotomy (PCNL) is regarded as one of the most demanding aspects of the procedure and only a minority of urologists perform this step without assistance by a radiologist. Currently a wide variation of fluoroscopic guided techniques is available in clinical practice. In this work we describe the most common fluoroscopic guided access techniques in a step-by-step manner aiming to assist on the standardization of their technique and terminology...
April 24, 2017: BJU International
https://www.readbyqxmd.com/read/28437021/optimal-outcome-achievement-in-partial-nephrectomy-for-t1-renal-masses-a-contemporary-analysis-of-open-and-robotic-cases
#18
Matthew J Maurice, Daniel Ramirez, Önder Kara, Ercan Malkoç, Ryan J Nelson, Khaled Fareed, Robert J Stein, Amr F Fergany, Jihad H Kaouk
OBJECTIVES: To compare optimal outcome achievement between open and robotic partial nephrectomy. PATIENTS AND METHODS: Using our institutional partial nephrectomy database, we reviewed 605 cases performed for unifocal clinical T1 renal masses in non-solitary kidneys from 2011-2015. Tetrafecta, which was defined as negative surgical margins, freedom from perioperative complications, ≥80% renal functional preservation, and no chronic kidney disease upstaging, was chosen as the composite optimal outcome...
April 24, 2017: BJU International
https://www.readbyqxmd.com/read/28432832/profiling-microrna-from-nephrectomy-and-biopsy-specimens-predictors-of-progression-and-survival-in-clear-cell-renal-cell-carcinoma
#19
Casey G Kowalik, Drew A Palmer, Travis B Sullivan, Patrick A Teebagy, John M Dugan, John A Libertino, Eric J Burks, David Canes, Kimberly M Rieger-Christ
OBJECTIVE: To identify miRNA characteristic of metastatic clear cell renal cell carcinoma (ccRCC) and those indicative of cancer specific survival in nephrectomy and biopsy specimens. We also sought to determine if a miRNA panel could differentiate benign from ccRCC tissue. MATERIALS AND METHODS: RNA was isolated from nephrectomy and kidney biopsy specimens (n=156; n=46 respectively). Samples were grouped: benign, non-progressive and progressive ccRCC. MiRNA were profiled by microarray and validated by qRT-PCR...
April 22, 2017: BJU International
https://www.readbyqxmd.com/read/28432830/prevalence-and-risk-factors-of-symptomatic-urinary-tract-infection-after-endoscopic-incision-for-the-treatment-of-ureterocele-in-children
#20
Kimihiko Moriya, Michiko Nakamura, Yoko Nishimura, Yukiko Kanno, Takeya Kitta, Masafumi Kon, Nobuo Shinohara
OBJECTIVE: To clarify the impact of endoscopic incision for ureterocele as an initial procedure, retrospective chart review was performed focusing on the prevalence and risk factors of symptomatic urinary tract infection after endoscopic incision. MATERIALS AND METHODS: Among children with ureterocele who were managed between September 1994 and April 2016, patients who were observed conservatively without additional surgical management after endoscopic incision were included in this study...
April 22, 2017: BJU International
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