journal
MENU ▼
Read by QxMD icon Read
search

BJU International

journal
https://www.readbyqxmd.com/read/28921938/prostate-cancer-treatment-in-renal-transplant-recipients-a-systematic-review
#1
REVIEW
Giancarlo Marra, Ettore Dalmasso, Marco Angello, Stefania Munegato, Andrea Bosio, Omidreza Sedigh, Luigi Biancone, Paolo Gontero
BACKGROUND: The majority of kidney transplants are performed in recipients (RTR) over 50; simultaneously their life expectancy is improving. The increasing age and number of RTR is likely to be paralleled by an increase of prostate cancer (PCa) incidence. However, little is known on the optimal management of these patients who represent a therapeutic challenge due to medical and anatomical graft-related issues. METHODS: AMED, Medline and Embase were searched until November 17(th) , 2016 adhering to the PRISMA guidelines and the AMSTAR checklist to investigate oncological and functional outcomes of PCa treatment in RTR...
September 18, 2017: BJU International
https://www.readbyqxmd.com/read/28921820/systematic-review-and-network-meta-analysis-on-the-relative-efficacy-of-osteoporotic-medications-men-with-prostate-cancer-on-continuous-androgen-deprivation-therapy%C3%A2-to-reduce-risk-of-fragility-fractures
#2
REVIEW
Yeesha Poon, Petros Pechlivanoglou, Shabbir M H Alibhai, David Naimark, Jeffrey S Hoch, Emmanuel Papadimitropoulos, Mary-Ellen Hogan, Murray Krahn
BACKGROUND: Androgen deprivation therapy (ADT) is an effective treatment for men with advanced prostate cancer, but loss of bone mineral density (BMD) is a major risk factor for fractures. This analysis evaluated the relative effectiveness of osteoporosis treatments using BMD as a surrogate endpoint for fragility fractures in men on continuous ADT. METHOD: We included randomized controlled trials studying bisphosphonates, denosumab, toremifene, and raloxifene in patients with non-metastatic prostate cancer on ADT for review...
September 18, 2017: BJU International
https://www.readbyqxmd.com/read/28921872/first-line-therapy-with-dacomitinib-an-orally-available-pan-her-tyrosine-kinase-inhibitor-for-locally-advanced-or-metastatic-penile-squamous-cell-carcinoma-results-of-an-open-label-single-arm-single-center-phase-2-study
#3
A Necchi, S Lo Vullo, F Perrone, D Raggi, P Giannatempo, G Calareso, N Nicolai, L Piva, D Biasoni, M Catanzaro, T Torelli, S Stagni, E Togliardi, M Colecchia, A Busico, A Gloghini, A Testi, L Mariani, R Salvioni
OBJECTIVE: To harness the frontline therapy in advanced penile squamous cell carcinoma (PSCC), for which chemotherapy exerts moderate activity but poor efficacy. Dacomitinib is an irreversible, pan-epidermal growth factor receptor (HER) inhibitor. PATIENTS AND METHODS: In a phase 2 study (NCT01728233), patients received dacomitinib 45 mg/day, orally, continuously. Inclusion criteria were SCC histology, clinical stage N2-3 or M1 (TNM 2009), and no prior chemotherapy administration...
September 16, 2017: BJU International
https://www.readbyqxmd.com/read/28921850/prospective-comparison-of-transperineal-mri-ultrasound-fusion-biopsy-and-transrectal-systematic-biopsy-in-biopsy-na%C3%A3-ve-patients
#4
Angelika Borkowetz, Boris Hadaschik, Ivan Platzek, Marieta Toma, Georgi Torsev, Theresa Renner, Roman Herout, Martin Baunacke, Michael Laniado, Gustavo Baretton, Jan Philipp Radtke, Claudia Kesch, Markus Hohenfellner, Michael Froehner, Heinz-Peter Schlemmer, Manfred Wirth, Stefan Zastrow
OBJECTIVES: To evaluate the value of multiparametric magnetic resonance imaging (mpMRI) for the detection of significant prostate cancer (PCa) and to compare transperineal MRI/ultrasound-fusion biopsy (fusPbx) to conventional transrectal systematic biopsy (sysPbx) in biopsy-naïve patients. PATIENTS AND METHODS: This multicentre, prospective trial investigated biopsy-naïve patients with suspicion of PCa undergoing transperineal fusPbx in combination with transrectal sysPbx (comPbx)...
September 16, 2017: BJU International
https://www.readbyqxmd.com/read/28921838/robotic-kidney-transplantation-comparison-of-the-first-40-cases-of-open-vs-robotic-transplantations-by-a-single-surgeon
#5
Volkan Tuğcu, Nevzat Can Şener, Selçuk Şahin, Abdullah Hızır Yavuzsan, Fatih Gökhan Akbay, Süheyla Apaydın
OBJECTIVE: To compare the outcomes of the first 40 cases who underwent robotic kidney transplantation (RKT) with those of the first 40 cases who underwent open kidney transplantation (KT) in the Dr. Sadi Konuk Training Hospital. MATERIAL AND METHODS: Between January 2016 and February 2017, we prospectively collected the data of the first 40 RKT cases (RKT group) and compared them with those of the first 40 open KT cases (OKT group). Comparisons were made using One-way ANOVA or the Kruskal-Wallis test for continuous variables, and the Chi-square or Fisher Exact test for categorical variables...
September 16, 2017: BJU International
https://www.readbyqxmd.com/read/28921833/guideline-of-guidelines-asymptomatic-microscopic-haematuria
#6
REVIEW
Brian J Linder, Edward J Bass, Hugh Mostafid, Stephen A Boorjian
OBJECTIVE: To review major organizational guidelines on the evaluation and management of asymptomatic microscopic haematuria (AMH). METHODS: This is a review of the haematuria guidelines from 1.) American Urological Association (AUA), 2.) consensus statement from the Canadian Urological Association, Canadian Urologic Oncology Group, and Bladder Cancer Canada, 3.) American College of Physicians (ACP), 4.) Joint Consensus Statement of the Renal Association (RA) and British Association of Urological Surgeons (BAUS), and 5...
September 16, 2017: BJU International
https://www.readbyqxmd.com/read/28905486/perioperative-allogeneic-blood-transfusion-does-not-adversely-impact-oncological-outcomes-after-radical-cystectomy-for-urinary-bladder-cancer-a-propensity-score-weighted-european-multicenter-study
#7
Malte W Vetterlein, Philipp Gild, Luis A Kluth, Thomas Seisen, Michael Gierth, Hans-Martin Fritsche, Maximilian Burger, Chris Protzel, Oliver W Hakenberg, Nicolas von Landenberg, Florian Roghmann, Joachim Noldus, Philipp Nuhn, Armin Pycha, Michael Rink, Felix K-H Chun, Matthias May, Margit Fisch, Atiqullah Aziz
OBJECTIVES: To evaluate the effect of perioperative blood transfusion (PBT) on recurrence-free survival (RFS), overall survival (OS), cancer-specific mortality (CSM), and other-cause mortality (OCM) in patients undergoing radical cystectomy (RC), utilizing a contemporary European multicenter cohort. PATIENTS AND METHODS: The PROspective MulticEnTer RadIcal Cystectomy Series (PROMETRICS) includes data on 679 patients who underwent RC at 18 European tertiary care centers in 2011...
September 14, 2017: BJU International
https://www.readbyqxmd.com/read/28872778/effects-of-thiazolidinedione-in-patients-with-active-bladder-cancer
#8
Roger Li, Michael J Metcalfe, J E Ferguson Rd, Sharada Mokkapati, Graciela M Nogueras González, Colin P Dinney, Neema Navai, David J McConkey, Sunil K Sahai, Ashish M Kamat
OBJECTIVE: To examine the influence of perioperative thiazolidinedione (TZD) on cancer-specific outcomes in patients undergoing radical cystectomy (RC) for urothelial carcinoma (UC). DESIGN, SETTING, AND PARTICIPANTS: A retrospective cohort of 173 diabetic patients undergoing RC from 2005 to 2010 was identified. Of those, 53 were on TZD treatment at the time of surgery, with 33 patients taking pioglitazone. Baseline clincopathologic characteristics, as well as cancer specific survival (CSS), recurrence free survival (RFS), and overall survival (OS) were compared between the patients on and off of TZD at the time of RC...
September 5, 2017: BJU International
https://www.readbyqxmd.com/read/28872774/prospective-randomized-non-inferiority-trial-of-pelvic-drain-placement-versus-no-pelvic-drain-placement-after-robot-assisted-radical-prostatectomy
#9
Avinash Chenam, Bertram Yuh, Ali Zhumkhawala, Nora Ruel, William Chu, Clayton Lau, Kevin Chan, Timothy Wilson, Jonathan Yamzon
OBJECTIVES: To determine if eliminating the prophylactic placement of a pelvic drain (PD) after robot-assisted radical prostatectomy (RARP) affects the incidence of early (90-day) postoperative adverse events. MATERIALS AND METHODS: In this parallel-group, blinded, non-inferiority trial, we randomized patients planning to undergo RARP to one of two arms: no drain placement (ND) or PD placement. Patients with demonstrable intra-operative leakage upon bladder irrigation were excluded...
September 5, 2017: BJU International
https://www.readbyqxmd.com/read/28872764/association-between-metabolic-syndrome-and-intravesical-prostatic-protrusion-in-benign-prostatic-enlargement-patients-with-lower-urinary-tract-symptoms-mips-study
#10
G I Russo, F Regis, P Spatafora, J Frizzi, D Urzì, S Cimino, S Serni, M Carini, M Gacci, G Morgia
OBJECTIVE: To investigate the association between metabolic syndrome (MetS) and morphological features of benign prostatic enlargement (BPE), including total prostate volume (TPV), transitional zone volume (TZV) and intra vesical prostatic protrusion (IPP). PATIENTS AND METHODS: From January 2015 to January 2017, 224 consecutive men older than 50 years presenting with lower urinary tract symptoms (LUTS) suggestive of BPE were recruited in this multicentre cross-sectional study...
September 5, 2017: BJU International
https://www.readbyqxmd.com/read/28872752/time-on-androgen-deprivation-therapy-and-adaptations-to-exercise-secondary-analysis-from-a-12-month-randomized-controlled-trial-in-men-with-prostate-cancer
#11
Dennis R Taaffe, Laurien M Buffart, Robert U Newton, Nigel Spry, James Denham, David Joseph, David Lamb, Suzanne K Chambers, Daniel A Galvão
OBJECTIVES: To explore if duration of prior exposure to androgen deprivation therapy (ADT) in men with prostate cancer (PCa) undertaking a yearlong exercise program moderates the exercise response on body composition and muscle performance. In addition, we explored the moderator effect of baseline testosterone, time since ADT, and baseline value of the outcome. PATIENTS AND METHODS: In a multicenter randomized controlled trial, 100 patients previously treated for either 6 months (short-term) or 18 months (long-term) ADT in combination with radiotherapy as part of the TROG 03...
September 5, 2017: BJU International
https://www.readbyqxmd.com/read/28872750/multi-centre-prospective-evaluation-of-the-seldinger-technique-for-difficult-male-urethral-catheter-insertions-by-non-urology-trained-doctors
#12
Yuigi Yuminaga, Jonathan Kam, Mark Louie-Johnsun
OBJECTIVE: To evaluate the safety and effectiveness of the Seldinger technique by non-urology trained (NUT) doctors for difficult male indwelling urinary catheter (IDC) insertions. PATIENTS AND METHODS: In all, 115 patients and 57 participating NUT doctors were recruited by the urologist or urology registrar, when contacted in regards to failed IDC insertion. The successful passage of an IDC by the NUT doctors using the Seldinger technique with a straight, hydrophilic guidewire was assessed in our prospective, multicentre evaluation...
September 5, 2017: BJU International
https://www.readbyqxmd.com/read/28834167/feasibility-and-safety-of-focal-irreversible-electroporation-as-salvage-treatment-for-localized-radio-recurrent-prostate-cancer
#13
Matthijs J Scheltema, Willemien van den Bos, Amila R Siriwardana, Anton M F Kalsbeek, James E Thompson, Francis Ting, Maret Böhm, Anne-Maree Haynes, Ron Shnier, Warick Delprado, Phillip D Stricker
OBJECTIVES: To evaluate the feasibility, safety, early quality of life (QoL) and oncological outcomes of salvage focal irreversible electroporation (IRE) for radio-recurrent prostate cancer (PCa). PATIENTS AND METHODS: Patients with localized, radio-recurrent PCa without evidence of metastatic or nodal disease were offered focal IRE following the consensus guidelines. Patients with a minimum follow-up of 6 months were eligible for analysis. Adverse events were monitored using the NCI Common Terminology Criteria for Adverse Events (CTCAE version 4...
August 21, 2017: BJU International
https://www.readbyqxmd.com/read/28834125/analysis-of-survival-for-patients-with-chronic-kidney-disease-primarily-related-to-renal-cancer-surgery
#14
Jitao Wu, Chalairat Suk-Ouichai, Wen Dong, Elvis Caraballo Antonio, Ithaar H Derweesh, Brian R Lane, Sevag Demirjian, Jianbo Li, Steven C Campbell
OBJECTIVES: To evaluate predictors of long-term survival for patients with chronic kidney disease primarily due to surgery (CKD-S). Patients with CKD-S have generally good survival that approximates patients who do not have CKD even after renal cancer surgery (RCS), yet there may be heterogeneity within this cohort. PATIENTS AND METHODS: From 1997 to 2008, 4 246 patients underwent RCS at our centre. The median (interquartile range [IQR]) follow-up was 9.4 (7.3-11...
August 21, 2017: BJU International
https://www.readbyqxmd.com/read/28834085/a-more-extended-lymph-node-dissection-template-at-radical-prostatectomy-detects-metastases-in-the-common-iliac-region-and-in-the-fossa-of-marcille
#15
Lydia Maderthaner, Marc A Furrer, Urs E Studer, Fiona C Burkhard, George N Thalmann, Daniel P Nguyen
OBJECTIVES: To assess the effect of adding lymph nodes (LN) located along the common iliac vessels and in the fossa of Marcille to the extended pelvic lymph node dissection (PLND) template at radical prostatectomy (RP). PATIENTS AND METHODS: At a referral center, RP and PLND were undergone by 485 patients from 2000 to 2008 (historical cohort: classical extended PLND template) and 268 patients from 2010 to 2015 (contemporary cohort: extended PLND template including LN located along the common iliac vessels and in the fossa of Marcille)...
August 21, 2017: BJU International
https://www.readbyqxmd.com/read/28834084/does-robot-assisted-radical-prostatectomy-benefit-prostate-cancer-patients-with-bone-oligometastases
#16
Won Sik Jang, Myung Soo Kim, Won Sik Jeong, Ki Don Chang, Kang Su Cho, Won Sik Ham, Koon Ho Rha, Sung Joon Hong, Young Deuk Choi
OBJECTIVE: To investigate perioperative and oncologic outcomes of robot-assisted radical prostatectomy (RARP) in oligometastatic prostate cancer (PCa). PATIENTS AND METHODS: We retrospectively reviewed the records of 79 oligometastatic PCa patients treated with RARP or ADT between 2005 and 2015 at our institution. Of these 79 patients, 38 were treated with RARP and 41 were treated with ADT without local therapy. Oligometastatic disease was defined as the presence of five or fewer hot spots detected by preoperative bone scan...
August 21, 2017: BJU International
https://www.readbyqxmd.com/read/28834013/management-of-metastatic-prostate-cancer-in-the-elderly-identifying-fitness-for-chemotherapy-in-the-post-stampede-world
#17
LETTER
A Thompson, M J Beresford, P Sarmah, E R Jefferies
The relative proportion of >75 is expected to double over the next 25 years and older men are more likely to be diagnosed with advanced disease. Meta-analysis of the eagerly awaited CHAARTED, STAMPEDE and GETUG15 trials have shown that men with newly diagnosed hormone sensitive metastatic prostate cancer (mPCa) who were treated with docetaxel in addition to ADT, showed a 9% absolute overall survival benefit at 4 years(1) . As such, European Association of Urology (EAU) guidelines recommend that newly diagnosed mPCa should be treated with castration plus docetaxel chemotherapy 'provided the patient is fit enough'...
August 19, 2017: BJU International
https://www.readbyqxmd.com/read/28805335/chipping-away-at-the-body-politic-one-study-at-a-time-the-case-for-more-unprofessional-online-content
#18
LETTER
Christopher E Bayne, Benjamin J Davies
Koo et al's recent paper[1] on unprofessional online content among US urology residency graduates has received attention in the lay press and social media outlets. The paper has an Altmetric Attention score of 341[2]-good for the fifth-most online-cited paper the BJUI has ever published. Seventeen news outlets have reported the study, including MSN, Medscape, and US News & World Report. This article is protected by copyright. All rights reserved.
August 14, 2017: BJU International
https://www.readbyqxmd.com/read/28805303/controlled-release-of-igf1-enhances-urethral-sphincter-function-and-histological-structure-in-the-treatment-of-female-stress-urinary-incontinence-in-a-rodent-model
#19
Hao Yan, Liren Zhong, Yaodong Jiang, Jian Yang, Junhong Deng, Shicheng Wei, Emmanuel Opara, Anthony Atala, Xiangming Mao, Margot Damaser, Yuanyuan Zhang
OBJECTIVES: Stress urinary incontinence (SUI) diminishes the quality of life of millions, particularly women who have delivered vaginally, which can injure the urethral sphincter. Despite several well-established treatments for SUI, growth factor therapy might provide an alternative to promote urethral sphincter repair. The goal of this study was to determine the effects of controlled release of IGF1 from alginate-poly-L-ornithine-gelatin microbeads (IGF1-A-PLO-G microbeads) on sphincter tissue regeneration in a rat model of SUI...
August 14, 2017: BJU International
https://www.readbyqxmd.com/read/28805298/female-urethral-injuries-associated-with-pelvic-fracture-a-systematic-review-of-the-literature
#20
REVIEW
Devin N Patel, Cynthia S Fok, George D Webster, Jennifer T Anger
OBJECTIVES: To systematically review the literature of female urethral injuries associated with pelvic fracture and determine optimal management of this rare injury. MATERIALS AND METHODS: Using Meta-analysis Of Observational Studies in Epidemiology criteria, we searched Cochrane, Pubmed and OVID databases for all articles available before June 30, 2016 using the terms "female pelvic fracture urethroplasty," "female urethral distraction," "female pelvic fracture urethral injury," "female pelvic fracture urethra girls...
August 14, 2017: BJU International
journal
journal
20051
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"