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BJU International

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https://www.readbyqxmd.com/read/29331084/baus-consensus-document-for-the-management-of-male-genital-emergencies-penile-amputation
#1
REVIEW
C J Shukla, G Brown, T Dorkin, M Lucky, R Pearcy, R W Rees, M Shabbir, D J Summerton, A Muneer
Male genital emergencies relating to the penis and scrotum are rare and require prompt investigation and surgical intervention. Clinicians are often unfamiliar with the management of these conditions and may not work in a specialist centre with on-site expertise in genitourethral surgery available. A series of consensus statements have been developed by an expert consensus comprising BAUS Section of Andrology and Genitourethral Surgery together with experts from units throughout the UK. Penile amputation is a rare gentile emergency and requires prompt intervention and microsurgical reconstruction...
January 13, 2018: BJU International
https://www.readbyqxmd.com/read/29322602/outcomes-of-more-than-1-000-percutaneous-nephrolithotomies-and-validation-of-guy-s-stone-score
#2
Petronio Augusto de Souza Melo, Fabio Carvalho Vicentini, Artur Agostinho Beraldi, Marcelo Hisano, Claudio Bovolenta Murta, Joaquim Francisco de Almeida Claro
OBJECTIVE: To present the experience with percutaneous nephrolithotomy (PCNL) at a high-volume Brazilian centre and to evaluate Guy's stone score (GSS) as a predictor of success and complications in PCNL. PATIENTS AND METHODS: We prospectively evaluated patients who underwent PCNL between June 2011 and October 2016. Indications for PCNL included renal stones larger than 2 cm and calculi smaller than 2 cm in which first-line techniques had failed. All patients underwent a complete pre-operative evaluation, including non-contrast-enhanced abdominal computed tomography (CT)...
January 11, 2018: BJU International
https://www.readbyqxmd.com/read/29319928/low-dose-rate-brachytherapy-for-prostate-cancer-outcomes-beyond-10-years-of-follow-up
#3
S Lazarev, M R Thompson, N N Stone, R G Stock
OBJECTIVES: To examine biochemical control, survival, and late morbidity with definitive low-dose-rate brachytherapy (LDR-BT) for prostate cancer patients surviving ≥10 years post-treatment. MATERIALS AND METHODS: We identified 757 men with localized prostate cancer who underwent definitive LDR-BT in the period 1990-2006 and were followed for ≥10 years at our institution. Biochemical failure-free survival (BFFS), distant metastases-free survival (DMFS), disease-specific survival (DSS), and overall survival (OS) were selected as study endpoints...
January 10, 2018: BJU International
https://www.readbyqxmd.com/read/29319927/which-outcome-measures-should-be-used-in-stress-urinary-incontinence-trials
#4
Renly Lim, Men Long Liong, Wing Seng Leong, Kah Hay Yuen
OBJECTIVE: To review measures used in recent randomized controlled trials evaluating stress urinary incontinence (SUI) treatments and to propose the most relevant outcome measure which should be included in future trials. MATERIALS AND METHODS: We identified randomized controlled trials for SUI interventions published between January 2015 and July 2017. We listed the objective and subjective outcome measures used in eligible trials in literature search. Using data from our randomized controlled trial conducted from 2013-2016 evaluating pulsed magnetic stimulation for SUI, we analysed the correlation between all measures...
January 10, 2018: BJU International
https://www.readbyqxmd.com/read/29319926/the-role-of-lymph-node-dissection-in-the-management-of-renal-cell-carcinoma-a-systematic-review-and-meta-analysis
#5
REVIEW
Bimal Bhindi, Christopher J D Wallis, Stephen A Boorjian, R Houston Thompson, Ann Farrell, Simon P Kim, Jose A Karam, Umberto Capitanio, Dragan Golijanin, Bradley C Leibovich, Boris Gershman
OBJECTIVES: To evaluate the role of retroperitoneal lymph node dissection (LND) in non-metastatic (M0) and metastatic (M1) renal cell carcinoma (RCC). PATIENTS AND METHODS: We searched Medline, EMBASE, Web of Science, and Scopus from database inception to August 29, 2017 for studies of patients who underwent partial or radical nephrectomy for M0 or M1 RCC. Two investigators independently selected studies for inclusion. Risk of bias was assessed using the Newcastle-Ottawa scale, Cochrane Collaboration tool, and NHLBI Quality Assessment Tool...
January 10, 2018: BJU International
https://www.readbyqxmd.com/read/29319922/the-effect-of-timing-of-an-immediate-instillation-with-mitomycin-c-after-transurethral-resection-in-941-non-muscle-invasive-bladder-cancer-patients
#6
Judith Bosschieter, R Jeroen A van Moorselaar, André N Vis, Tessa van Ginkel, Birgit I Lissenberg-Witte, Goedele M A Beckers, Jakko A Nieuwenhuijzen
OBJECTIVES: To investigate whether timing of an immediate instillation (on the day of transurethral resection or one day later) has impact on time to recurrence of non-muscle-invasive bladder cancer. PATIENTS AND METHODS: All patients with non-muscle-invasive bladder cancer who were enrolled in a prospective trial between 1998 and 2003 and treated with an early mitomycin C instillation (on the day of transurethral resection or one day later), were selected. Statistical analysis was performed with Kaplan-Meier curves and multivariable Cox regression...
January 10, 2018: BJU International
https://www.readbyqxmd.com/read/29319919/outcomes-and-toxicities-in-intermediate-risk-prostate-cancer-patients-treated-with-brachytherapy-alone-or-brachytherapy-and-supplemental-external-beam-radiation-therapy
#7
Emily Schlussel Markovic, Michael Buckstein, Nelson N Stone, Richard G Stock
OBJECTIVE: To evaluate the cancer control outcomes and long-term treatment-related morbidity of brachytherapy as well as combination brachytherapy and EBRT in patients with intermediate-risk prostate cancer. MATERIALS AND METHODS: A retrospective review was conducted in a prospectively collected database of patients with intermediate-risk prostate cancer who were treated either with brachytherapy or brachytherapy and EBRT, with or without ADT, from 1990-2014. Urinary and erectile dysfunction symptoms are measured using the International Prostate Symptom Score (IPSS) and the Mount Sinai erectile function scale, and the Sexual Health Inventory for Men (SHIM), respectively...
January 10, 2018: BJU International
https://www.readbyqxmd.com/read/29319917/nerve-sparing-cystectomy-has-a-beneficial-impact-on-urinary-continence-after-othotopic-bladder-substitution-which-becomes-even-more-apparent-over-time
#8
Marc A Furrer, Urs E Studer, Tobias Gross, Fiona C Burkhard, George N Thalmann, Daniel P Nguyen
OBJECTIVES: To analyse urinary continence in long-term survivors after cystectomy and orthotopic bladder substitute according to attempted nerve-sparing status. MATERIALS AND METHODS: We analysed 180 consecutive patients treated at our department between 1985 and 2007 who underwent cystectomy with orthotopic bladder substitution, and survived ≥10 years post-cystectomy. We stratified patients by attempted nerve-sparing status and evaluated continence outcomes using descriptive statistics and Cox proportional hazards regression models...
January 10, 2018: BJU International
https://www.readbyqxmd.com/read/29319914/aquablation-therapy-for-symptomatic-benign-prostatic-hyperplasia-single-center-experience-in-47-patients
#9
Mihir M Desai, Abhishek Singh, Shashank Abhishek, Abhishek Laddha, Harshad Pandya, Akbar N Ashrafi, Arvind P Ganpule, Claus G Roehrborn, Andrew J Thomas, Mahesh Desai, Ravindra B Sabnis
OBJECTIVE: To report procedure process improvements and confirm preserved safety and short-term effectiveness of a second-generation Aquablation device for the treatment of lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) in 47 consecutive patients at a single institution. PATIENTS AND METHODS: Aquablation was performed in 47 patients with symptomatic BPH at a single institution. Baseline, perioperative and 3-month urinary function data were collected...
January 10, 2018: BJU International
https://www.readbyqxmd.com/read/29281857/outcomes-of-subsequent-non-muscle-invasive-bladder-cancer-treated-with-intravesical-bacillus-calmette-gu%C3%A3-rin-after-radical-nephroureterectomy-for-upper-urinary-tract-urothelial-carcinoma-a-propensity-matched-analysis-with-primary-bladder-cancer
#10
Makito Miyake, Yoshihiro Tatsumi, Hiroaki Matsumoto, Kazuhiro Nagao, Hideyasu Matsuyama, Teruo Inamoto, Haruhito Azuma, Hiroaki Yasumoto, Hiroaki Shiina, Kiyohide Fujimoto
OBJECTIVES: To describe the clinicopathologic characteristics and prognosis of subsequent non-muscle invasive bladder cancer (NMIBC) after radical nephroureterectomy for upper urinary tract urothelial carcinoma (UTUC), particularly its response to intravesical Bacillus Calmette-Guérin (BCG). PATIENTS AND METHODS: An observational study was conducted in 1463 patients with UTUC who had undergone radical nephroureterectomy and in 1555 patients with primary NMIBC. Of the 1463 UTUC patients, 256 (17%) subsequently developed NMIBC (UTUC-NMIBC) and were available for the analysis...
December 27, 2017: BJU International
https://www.readbyqxmd.com/read/29281853/racial-disparity-and-survival-outcomes-between-african-american-and-caucasian-men-with-penile-cancer
#11
Chad R Ritch, Nachiketh Soodana Prakash, Nicola Pavan, Raymond R Balise, Maria Camila Velasquez, Mahmoud Alameddine, Desmond Y Adamu, Sanoj Punnen, Dipen J Parekh, Mark L Gonzalgo
OBJECTIVE: To determine whether there was a survival difference for AAM versus CM with penile squamous cell carcinoma (pSCC), particularly in locally advanced and metastatic cases where disease mortality is highest. METHODS: Using the Florida Cancer Data System, we identified men with pSCC from 2005 to 2013. We compared age, follow-up, stage, race, and treatment type between AAM and CM. We performed Kaplan-Meier analysis for overall survival (OS) between AAM and CM for all stages, and for those with locally advanced and metastatic disease...
December 27, 2017: BJU International
https://www.readbyqxmd.com/read/29281852/evolution-of-cystectomy-care-over-a-11-years-period-in-a-high-volume-tertiary-referral-center
#12
Aldo Brassetti, Axel Möller, Oscar Laurin, Jonas Höijer, Christofer Adding, Ayako Miyakawa, Abolfazl Hosseini, Peter Wiklund
OBJECTIVES: To describe the evolution RC care over 11 years in a referral center. MATERIALS AND METHODS: Clinical data of patients undergoing either open RC (ORC) or robot-assisted RC (RARC) for cT1-4aN0M0 bladder cancer (BCa) at our center between 01/2006 and 12/2016 were retrospectively evaluated. Crude and propensity score weighted log-binomial regression analyses assessed the association between pre-/perioperative variables and the risk of reoperation, intensive care unit (ICU) admission and death within 90 days after RC...
December 27, 2017: BJU International
https://www.readbyqxmd.com/read/29281848/propensity-matched-comparative-analysis-of-survival-following-chemoradiation-or-radical-cystectomy-for-muscle-invasive-bladder-cancer
#13
Chad R Ritch, Raymond Balise, Nachiketh Soodana Prakash, David Alonzo, Katherine Almengo, Mahmoud Alameddine, Vivek Venkatramani, Sanoj Punnen, Dipen Parekh, Mark L Gonzalgo
OBJECTIVE: To compare survival outcome between chemoradiation and radical cystectomy for Muscle invasive bladder cancer(MIBC). MATERIALS AND METHODS: A retrospective analysis was performed using muscle-invasive bladder cancer (≥cT2, N0, M0) patients in the National Cancer Database (2004-2013). Chemoradiation was defined as radiation dose ≥40Gy and chemotherapy within 90d of radiation. Descriptive statistics were used to compare groups. Radical cystectomy and chemoradiation patients were propensity matched...
December 27, 2017: BJU International
https://www.readbyqxmd.com/read/29281846/men-don-t-talk-about-their-health-but-will-they-chat-the-potential-of-online-holistic-needs-assessment-in-prostate-cancer
#14
LETTER
Veronica Nanton, Rebecca Appleton, Joelle Loew, Nisar Ahmed, Sam Ahmedzai, Jeremy Dale
Men don't talk about their health is a familiar trope. Evidence suggests that in the United States (US) and in the United Kingdom (UK) this is indeed the case. A survey of five hundred men in the US over the age of eighteen reported only 7% discussing their health with their peers [1]. Only 42% of men surveyed were prepared to consult a health care professional over a worrying symptom [1]. This article is protected by copyright. All rights reserved.
December 27, 2017: BJU International
https://www.readbyqxmd.com/read/29274202/-very-low-risk-bladder-tumours-a-new-entity
#15
Ofer N Gofrit, Dov Pode, Galina Pizov, Mordechai Duvdevani, Ezekiel H Landau, Guy Hidas, Vladimir Yutkin
OBJECTIVE: To evaluate the homogeneity of the "low-risk" bladder cancer group in an attempt to optimize follow-up protocols. PATIENTS AND METHODS: Between June 1998 and December 2008, 211 patients (mean age of 66.7 years, S.D 12.8) underwent transurethral resection of low-risk bladder cancer. Post-operative follow-up included cystoscopy at 3 and 12 months after surgery and then annually for a total of 5 years and then annual ultrasonography indefinitely. RESULTS: After a median follow-up of 10 years, 65 patients (30...
December 23, 2017: BJU International
https://www.readbyqxmd.com/read/29247473/the-movember-foundation-s-gap3-cohort-a-profile-of-the-largest-global-prostate-cancer-active-surveillance-database-to-date
#16
S M Bruinsma, L Zhang, M J Roobol, C H Bangma, E W Steyerberg, D Nieboer, M Van Hemelrijck
OBJECTIVES: The Movember Foundation launched the Global Action Plan Prostate Cancer Active Surveillance (GAP3) initiative to create a global consensus on the selection and monitoring of men with low-risk prostate cancer (PCa) on active surveillance (AS). The aim of this study is to present data on inclusion and follow-up for AS in this unique global AS database. SUBJECTS/PATIENTS (OR MATERIALS) AND METHODS: Between 2014 and 2016, the database was created by combining patient data from 25 established AS cohorts worldwide (USA, Canada, Australasia, UK, Europe) (n=15,101)...
December 15, 2017: BJU International
https://www.readbyqxmd.com/read/29239082/utility-of-early-transperineal-template-guided-prostate-biopsy-for-risk-stratification-in-men-undergoing-active-surveillance-for-prostate-cancer
#17
James Voss, Raj Pal, Shaista Ahmed, Magnus Hannah, Adil Jaulim, Thomas Walton
OBJECTIVE: To assess the accuracy and utility of routine multiparametric magnetic resonance imaging (mpMRI) and transperineal template-guided prostate biopsy (TPB) after enrolment in active surveillance (AS). PATIENTS AND METHODS: From April 2012 to December 2016 consecutive men from our single institution, diagnosed with low- or intermediate-risk prostate cancer on transrectal ultrasonography-guided biopsy, were offered further staging with early mpMRI and TPB within 12 months of diagnosis...
December 14, 2017: BJU International
https://www.readbyqxmd.com/read/29237233/mri-cognitive-fusion-biopsy-is-near-enough-good-enough
#18
LETTER
Niranjan J Sathianathen, Daniel Christidis, Badrinath R Konety, Nathan L Lawrentschuk
The evidence supporting the use of MRI-fusion biopsies over blind, systematic methods is mounting quickly and has subsequently led to several institutions embracing this new technique and technology. However, questions still remain whether there is difference between the modes of fusion - cognitive, software-based and in-bore - in terms of cancer detection. While it appears intuitive that software and in-bore approaches would be more accurate than cognitive targeting, many studies have failed to demonstrate a significant difference...
December 13, 2017: BJU International
https://www.readbyqxmd.com/read/29235239/familial-risks-in-urolithiasis-in-the-population-of-sweden
#19
Kari Hemminki, Otto Hemminki, Asta Försti, Kristina Sundquist, Jan Sundquist, Xinjun Li
OBJECTIVES: To assess detailed familial risks for medically diagnosed urolithiasis (UL, urinary tract stone disease) based on nationwide hospital and population records. SUBJECTS/PATIENTS AND METHODS: Subjects were identified from the Swedish Multigeneration Register in which 211,718 UL patients. Standardized incidence ratios (SIRs) were calculated by comparison to individuals without a family history of UL. RESULTS: The highest familial SIRs were invariably found for the same (concordant) type of UL: 2...
December 13, 2017: BJU International
https://www.readbyqxmd.com/read/29232047/antibiotic-prophylaxis-in-ureteroscopic-lithotripsy-a%C3%A2-systematic-review-and-meta-analysis-of-comparative-studies
#20
Tuo Deng, Bing Liu, Xiaolu Duan, Chao Cai, Zhijian Zhao, Wei Zhu, Junhong Fan, Wenqi Wu, Guohua Zeng
OBJECTIVE: To explore the efficacy and detailed strategies of antibiotic prophylaxis in ureteroscopic lithotripsy (URL) through a systematic review and meta-analysis. MATERIALS AND METHODS: A systematic literature search using Pubmed, Embase, Medline, Cochrane Library, CBM, CNKI and VIP databases was performed to obtain comparative studies on the efficacy of different antibiotic prophylaxis strategies in URL for preventing postoperative infections. The last search was conducted on June 25, 2017...
December 12, 2017: BJU International
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