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Archives of Disease in Childhood

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https://www.readbyqxmd.com/read/28931531/clinical-and-cost-effectiveness-of-the-lightning-process-in-addition-to-specialist-medical-care-for-paediatric-chronic-fatigue-syndrome-randomised-controlled-trial
#1
Esther M Crawley, Daisy M Gaunt, Kirsty Garfield, William Hollingworth, Jonathan A C Sterne, Lucy Beasant, Simon M Collin, Nicola Mills, Alan A Montgomery
OBJECTIVE: Investigate the effectiveness and cost-effectiveness of the Lightning Process (LP) in addition to specialist medical care (SMC) compared with SMC alone, for children with chronic fatigue syndrome (CFS)/myalgic encephalitis (ME). DESIGN: Pragmatic randomised controlled open trial. Participants were randomly assigned to SMC or SMC+LP. Randomisation was minimised by age and gender. SETTING: Specialist paediatric CFS/ME service. PATIENTS: 12-18 year olds with mild/moderate CFS/ME...
September 20, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28918383/liver-transplantation-in-children-state-of-the-art-and-future-perspectives
#2
REVIEW
Rohit Kohli, Miriam Cortes, N D Heaton, Anil Dhawan
In this review, we provide a state of the art of liver transplantation in children, as the procedure is now carried out for more than 30 years and most of our paediatric colleagues are managing these patients jointly with liver transplant centres. Our goal for this article is to enhance the understanding of the liver transplant process that a child and his family goes through while explaining the surgical advances and the associated complications that could happen in the immediate or long-term follow-up. We have deliberately introduced the theme that 'liver transplant is a disease' and 'not a cure', to emphasise the need for adherence with immunosuppression, a healthy lifestyle and lifelong medical follow-up...
September 16, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28916514/the-wisdom-of-investigating-early-developmental-impairment
#3
EDITORIAL
Arnab Kumar Seal
No abstract text is available yet for this article.
September 15, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28912166/breastfeeding-and-vitamin-d
#4
LETTER
Chika Edward Uzoigwe, Omer Ali
No abstract text is available yet for this article.
September 14, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28912165/holistic-care-of-complicated-tuberculosis-in-healthcare-settings-with-limited-resources
#5
Trevor Duke, Sharon Kasa Tom, Harry Poka, Henry Welch
In recent years, most of the focus on improving the quality of paediatric care in low-income countries has been on improving primary care using the Integrated Management of Childhood Illness, and improving triage and emergency treatment in hospitals aimed at reducing deaths in the first 24 hours. There has been little attention paid to improving the quality of care for children with chronic or complex diseases. Children with complicated forms of tuberculosis (TB), including central nervous system and chronic pulmonary TB, provide examples of acute and chronic multisystem paediatric illnesses that commonly present to district-level and second-level referral hospitals in low-income countries...
September 14, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28912164/highs-and-lows-of-diabetic-care-lessons-from-a-national-audit
#6
Justin T Warner
No abstract text is available yet for this article.
September 14, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28912163/neonatal-resuscitation-using-a-laryngeal-mask-airway-a-randomised-trial-in-uganda
#7
Nicolas J Pejovic, Daniele Trevisanuto, Clare Lubulwa, Susanna Myrnerts Höök, Francesco Cavallin, Josaphat Byamugisha, Jolly Nankunda, Thorkild Tylleskär
OBJECTIVE: Mortality rates from birth asphyxia in low-income countries remain high. Face mask ventilation (FMV) performed by midwives is the usual method of resuscitating neonates in such settings but may not always be effective. The i-gel is a cuffless laryngeal mask airway (LMA) that could enhance neonatal resuscitation performance. We aimed to compare LMA and face mask (FM) during neonatal resuscitation in a low-resource setting. SETTING: Mulago National Referral Hospital, Kampala, Uganda...
September 14, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28903953/looking-after-each-other-when-a-child-dies
#8
EDITORIAL
Martin Ward Platt
No abstract text is available yet for this article.
September 13, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28903952/humidified-high-flow-nasal-cannula-oxygen-for-bronchiolitis-should-we-go-with-the-flow
#9
LETTER
Ariel O Mace, James Gibbons, André Schultz, Geoff Knight, Andrew C Martin
No abstract text is available yet for this article.
September 13, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28903951/managing-problematic-severe-asthma-beyond-the-guidelines
#10
REVIEW
Katharine C Pike, Mark L Levy, John Moreiras, Louise Fleming
This review discusses issues related to managing problematic severe asthma in children and young people. A small minority of children have genuinely severe asthma symptoms which are difficult to control. Children with genuinely severe asthma need investigations and treatments beyond those described within conventional guidelines. However, the majority of children with poor symptom control despite high-intensity treatment achieve improvement in their asthma control once attention has been paid to the basics of asthma management...
September 13, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28903950/hearing-the-voices-of-children-and-young-people-to-develop-and-test-a-patient-reported-experience-measure-in-a-specialist-paediatric-setting
#11
Jo Wray, Sylvie Hobden, Sarah Knibbs, Geralyn Oldham
OBJECTIVE: To develop and test patient-reported experience measures (PREMs) for children and young people in a specialist paediatric hospital setting. DESIGN: Six PREMs were developed and tested by children and young people for children and young people aged 8-11, 12-13 and 14-16 years in inpatient and outpatient settings. A week-long pilot was implemented across inpatient wards and outpatient clinics to identify facilitators and barriers to the routine use of PREMs in a real-time setting across our organisation...
September 13, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28899877/multiresistant-e-coli-urine-infections-in-children-a-case-control-study
#12
Gayathri Raman, Brendan McMullan, Peter Taylor, Kylie-Ann Mallitt, Sean E Kennedy
OBJECTIVE: Urinary tract infections (UTIs) caused by resistant organisms are increasing which poses challenges when selecting empirical antimicrobial therapy. The aim of this study is to determine risk factors for multiresistant Escherichia coliUTIs in children. DESIGN: We included all reported urinary isolates from a children's hospital collected between January 2010 and June 2013. Patients who had multiresistant E. coliUTIs were identified and a retrospective review of medical records performed...
September 12, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28899876/treatment-and-management-of-children-with-haemolytic-uraemic-syndrome
#13
REVIEW
Patrick R Walsh, Sally Johnson
Haemolytic uraemic syndrome (HUS), comprising microangiopathic haemolytic anaemia, thrombocytopaenia and acute kidney injury, remains the leading cause of paediatric intrinsic acute kidney injury, with peak incidence in children aged under 5 years. HUS most commonly occurs following infection with Shiga toxin-producing Escherichia coli (STEC-HUS). Additionally, HUS can occur as a result of inherited or acquired dysregulation of the alternative complement cascade (atypical HUS or aHUS) and in the setting of invasive pneumococcal infection...
September 12, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28882881/respiratory-manifestations-of-gastro-oesophageal-reflux-in-children
#14
REVIEW
Fernando Maria de Benedictis, Andrew Bush
Gastro-oesophageal reflux disease (GORD) is a complex problem in children. Suspected respiratory manifestations of GORD, such as asthma, chronic cough and laryngitis, are commonly encountered in the paediatric practice, but continue to be entities with more questions than answers. The accuracy of diagnostic tests (ie, pH or pH-impedance monitoring, laryngoscopy, endoscopy) for patients with suspected extraoesophageal manifestations of GORD is suboptimal and therefore whether there is a causal relationship between these conditions remains largely undetermined...
September 7, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28874367/leukaemia-cutis-of-the-scalp
#15
Kwan Rui, Chan Mei Yoke, Low Yee, Lam Joyce Ching Mei
No abstract text is available yet for this article.
September 5, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28866628/identifying-paediatric-sepsis-the-difficulties-in-following-recommended-practice-and-the-creation-of-our-own-pathway
#16
LETTER
Rebecca Powell, Kerry Jeavons
No abstract text is available yet for this article.
September 2, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28860211/excess-all-cause-mortality-before-age-30-in-childhood-onset-type-1-diabetes-data-from-the-brecon-group-cohort-in-wales
#17
Diana R Wasag, John W Gregory, Colin Dayan, John N Harvey
BACKGROUND: Long-term outcomes in young people with type 1 diabetes continue to be of interest, and may help evaluate the effects of changes to the clinical care of children that have occurred in recent decades. AIMS: To identify mortality and its causes before age 30 years in patients developing type 1 diabetes before age 15 years. METHODS: Since 1995, paediatricians in Wales have compiled a prospective register of incident cases of type 1 diabetes occurring before age 15 years in Wales (the Brecon Cohort)...
August 31, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28855231/inequalities-in-the-dental-health-needs-and-access-to-dental-services-among-looked-after-children-in-scotland-a-population-data-linkage-study
#18
Alex D McMahon, Lawrie Elliott, Lorna Md Macpherson, Katharine H Sharpe, Graham Connelly, Ian Milligan, Philip Wilson, David Clark, Albert King, Rachael Wood, David I Conway
BACKGROUND: There is limited evidence on the health needs and service access among children and young people who are looked after by the state. The aim of this study was to compare dental treatment needs and access to dental services (as an exemplar of wider health and well-being concerns) among children and young people who are looked after with the general child population. METHODS: Population data linkage study utilising national datasets of social work referrals for 'looked after' placements, the Scottish census of children in local authority schools, and national health service's dental health and service datasets...
August 30, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28855230/live-attenuated-influenza-vaccine-laiv-recent-effectiveness-results-from-the-usa-and-implications-for-laiv-programmes-elsewhere
#19
REVIEW
Richard Pebody, Jim McMenamin, Hanna Nohynek
The USA has a long-standing paediatric influenza vaccination programme, including use of live attenuated influenza vaccine (LAIV). Following US evidence of apparent lack of vaccine effectiveness (VE) of LAIV in 2015/2016, particularly against A(H1N1)pdm09, the USA suspended the use of LAIV in the 2016/2017 season. The UK introduced LAIV for children in 2013/2014 and Finland in 2015/2016. Both countries have since been closely monitoring programme performance. In 2015/2016, the UK and Finland, unlike the USA, found evidence of significant VE of LAIV against laboratory-confirmed influenza...
August 30, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28855229/niacin-nad-and-malformations
#20
Robert Scott-Jupp
No abstract text is available yet for this article.
August 30, 2017: Archives of Disease in Childhood
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