journal
MENU ▼
Read by QxMD icon Read
search

Archives of Disease in Childhood

journal
https://www.readbyqxmd.com/read/28626020/lack-of-effect-of-vitamin-d3-supplementation-in-autism-a-20-week-placebo-controlled-rct
#1
Conor P Kerley, Clare Power, Louise Gallagher, David Coghlan
OBJECTIVES: Data suggest a potential role for vitamin D in autism spectrum disorder (ASD). We wanted to assess the effect of vitamin D3 supplementation compared with placebo in children with ASD. DESIGN: This was a double-blind, randomised, placebo-controlled trial. SETTING: A paediatric outpatient centre at high latitude over the winter season in Dublin, Ireland (53°N). PATIENTS: 42 children with ASD. INTERVENTIONS: 2000 IU vitamin D3 supplementation or placebo daily for 20 weeks...
June 16, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28611070/tackling-the-childhood-obesity-crisis-acute-paediatricians-are-not-playing-their-part
#2
LETTER
Kate Christina Harvey, Helen McDermott, William Coles, Susanne Elliott, Nicola McMullan, Archana Anandaram, Sanaa Ismail, Emma Webb, Jeremy Kirk
No abstract text is available yet for this article.
June 13, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28611069/paediatrics-in-russia-past-present-and-future
#3
Alexander Baranov, Leyla Namazova-Baranova, Valery Albitsky, Natalia Ustinova, Rimma Terletskaya, Olga Komarova
No abstract text is available yet for this article.
June 13, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28611068/early-growth-in-children-with-coeliac-disease-a-cohort-study
#4
Christian R Kahrs, Maria C Magnus, Hein Stigum, Knut E A Lundin, Ketil Størdal
OBJECTIVES: We aimed to study growth during the first 2 years of life in children later diagnosed with coeliac disease compared with children without, in a time with changing epidemiology and improved diagnostics. DESIGN: A prospective population-based pregnancy cohort study. SETTING: The nationwide Norwegian Mother and Child Cohort Study. PATIENTS: 58 675 children born between 2000 and 2009 with prospectively collected growth data...
June 13, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28611067/maximising-paediatricians-roles-in-improving-children-s-oral-health-lessons-from-leicester
#5
REVIEW
Jasmine Murphy, Rod Moore
AIMS: To provide an overview of steps taken to improve oral health in one UK city and to review factors relevant to maximising the contribution that paediatricians (and potentially other health professionals) can make to improving oral health. METHODS: The article provides information on the strategic approach taken in Leicester, one of the most ethnically diverse cities in England, and also one of the most deprived. Over a third of children aged 3 years, and half of those aged 5 years, have experience of obvious dental decay...
June 13, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28611066/should-patients-with-coeliac-disease-pay-for-their-treatment
#6
EDITORIAL
John W Puntis, Mark Peter Tighe
No abstract text is available yet for this article.
June 13, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28601795/the-role-of-nurses-clinical-impression-in-the-first-assessment-of-children-at-the-emergency-department
#7
Joany M Zachariasse, Dominique van der Lee, Nienke Seiger, Evelien de Vos-Kerkhof, Rianne Oostenbrink, Henriëtte A Moll
OBJECTIVE: To assess the diagnostic value and determinants of nurses' clinical impression for the recognition of children with a serious illness on presentation to the emergency department (ED). DESIGN: Secondary analysis of a prospective cohort. SETTING AND PATIENTS: 6390 consecutive children <16 years of age presenting to a paediatric ED with a non-surgical chief complaint and complete data available. MAIN OUTCOME MEASURES: Diagnostic accuracy of nurses' clinical impression for the prediction of serious illness, defined by intensive care unit (ICU) and hospital admission...
June 10, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28600385/trends-in-scottish-newborn-screening-programme-for-congenital-hypothyroidism-1980-2014-strategies-for-reducing-age-at-notification-after-initial-and-repeat-sampling
#8
Chourouk Mansour, Yasmine Ouarezki, Jeremy Jones, Moira Fitch, Sarah Smith, Avril Mason, Malcolm Donaldson
OBJECTIVES: To determine ages at first capillary sampling and notification and age at notification after second sampling in Scottish newborns referred with elevated thyroid-stimulating hormone (TSH). SUBJECTS AND METHODS: Referrals between 1980 and 2014 inclusive were grouped into seven 5-year blocks and analysed according to agreed standards. RESULTS: Of 2 116 132 newborn infants screened, 919 were referred with capillary TSH elevation ≥8 mU/L of whom 624 had definite (606) or probable (18) congenital hypothyroidism...
June 9, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28588046/breastfeeding-and-obesity
#9
Robert Scott-Jupp
No abstract text is available yet for this article.
June 6, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28588045/assessing-the-impact-of-in-utero-exposures-potential-effects-of-paracetamol-on-male-reproductive-development
#10
REVIEW
Karen R Kilcoyne, Rod T Mitchell
Human male reproductive disorders (cryptorchidism, hypospadias, testicular cancer and low sperm counts) are common and some may be increasing in incidence worldwide. These associated disorders can arise from subnormal testosterone production during fetal life. This has resulted in a focus on in-utero environmental influences that may result in reproductive effects on the offspring in later life. Over recent years, there has been a dramatic increase in the scientific literature describing associations between in-utero environmental exposures (eg, industrial chemicals and pharmaceuticals) and subsequent reproductive outcomes in male offspring...
June 6, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28588044/treatment-of-obesity-in-adolescents-where-should-interventions-focus
#11
EDITORIAL
Peymane Adab
No abstract text is available yet for this article.
June 6, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28584070/the-natural-history-of-prenatally-diagnosed-congenital-cystic-lung-lesions-long-term-follow-up-of-119-cases
#12
James Cook, Lyn S Chitty, Paolo De Coppi, Michael Ashworth, Colin Wallis
BACKGROUND: A paucity of evidence regarding the natural history of congenital pulmonary airway malformations (CPAMs) and pulmonary sequestration (PS) has resulted in a divergence in management strategy of asymptomatic cases. METHODS: We describe the long-term clinical course of 119 children diagnosed with these lesions treated at Great Ormond Street Hospital (GOSH). Cases were identified via the GOSH patient database. Study entry required the identification of a cystic lung lesion on prenatal ultrasound and confirmation of CPAM/PS on postnatal CT imaging...
June 5, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28584069/developing-guidelines-in-low-income-and-middle-income-countries-lessons-from-kenya
#13
Mike English, Grace Irimu, Rachel Nyamai, Fred Were, Paul Garner, Newton Opiyo
There are few examples of sustained nationally organised, evidence-informed clinical guidelines development processes in Sub-Saharan Africa. We describe the evolution of efforts from 2005 to 2015 to support evidence-informed decision making to guide admission hospital care practices in Kenya. The approach to conduct reviews, present evidence, and structure and promote transparency of consensus-based procedures for making recommendations improved over four distinct rounds of policy making. Efforts to engage important voices extended from government and academia initially to include multiple professional associations, regulators and practitioners...
June 5, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28554892/extrapolation-in-the-development-of-paediatric-medicines-examples-from-approvals-for-biological-treatments-for-paediatric-chronic-immune-mediated-inflammatory-diseases
#14
REVIEW
Anna M Stefanska, Dorota Distlerová, Joachim Musaus, Thorsten M Olski, Kristina Dunder, Tomas Salmonson, Dirk Mentzer, Jan Müller-Berghaus, Robert Hemmings, Richard Veselý
The European Union (EU) Paediatric Regulation requires that all new medicinal products applying for a marketing authorisation (MA) in the EU provide a paediatric investigation plan (PIP) covering a clinical and non-clinical trial programme relating to the use in the paediatric population, unless a waiver applies. Conducting trials in children is challenging on many levels, including ethical and practical issues, which may affect the availability of the clinical evidence. In scientifically justified cases, extrapolation of data from other populations can be an option to gather evidence supporting the benefit-risk assessment of the medicinal product for paediatric use...
May 29, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28550148/an-infant-with-diffuse-bullous-lesions
#15
Soheila Nasiri, Farahnaz Bidari Zerehpoosh, Sahar Dadkhahfar, Nafiseh Mortazavi, Nikoo Mozafari
No abstract text is available yet for this article.
May 26, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28550147/what-is-the-dose-of-intravenous-paracetamol-for-pain-relief-in-neonates
#16
EDITORIAL
Paola Mian, Catherijne Aj Knibbe, Dick Tibboel, Karel Allegaert
No abstract text is available yet for this article.
May 26, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28550146/does-painless-rectal-bleeding-equate-to-a-colonic-polyp
#17
Alison Morag Campbell, Ian Sugarman
BACKGROUND: It is often stated that if a patient presents with 'painless rectal bleeding' then a rectal polyp is the probable diagnosis. The aim of this study is to review our experience of children undergoing endoscopy to assess if the above statement is correct. METHODS: The senior author keeps a prospective database of every child undergoing flexible sigmoidoscopy or colonoscopy. As part of this database, the symptoms and signs that the patient presents with, specifically abdominal pain, diarrhoea, mucous per rectum and rectal bleeding, are recorded...
May 26, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28550145/paediatric-innovation-in-pakistan-our-experience-and-a-call-to-action
#18
Walid Farooqi, Faysal Subhani, Asad Mian
Standardisation in paediatric medicine may have the unintended effect of stifling innovation. Thinking outside the box becomes even more important in low-income to middle-income countries like Pakistan, where a large paediatric population requires healthcare. In addition, there is always a lack of funds, making an innovative, low-cost and high impact solution all the more necessary. While regulation and formal research is an integral part of the process, the local synthesis of a solution must start with a creative idea...
May 26, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28501810/alveolar-rhabdomyosarcoma-in-a-6-month-old-boy
#19
Andrea Bassi, Barbara Zamma Gallarati, Iacopo Sardi, Milena Guidi, Chiara Caporalini, Paola Pelosi, Maurizio de Martino
No abstract text is available yet for this article.
May 13, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28501809/non-specific-effects-of-vaccines-plausible-and-potentially-important-but-implications-uncertain
#20
REVIEW
Andrew J Pollard, Adam Finn, Nigel Curtis
Non-specific effects (NSE) or heterologous effects of vaccines are proposed to explain observations in some studies that certain vaccines have an impact beyond the direct protection against infection with the specific pathogen for which the vaccines were designed. The importance and implications of such effects remain controversial. There are several known immunological mechanisms which could lead to NSE, since it is widely recognised that the generation of specific immunity is initiated by non-specific innate immune mechanisms that may also have wider effects on adaptive immune function...
May 13, 2017: Archives of Disease in Childhood
journal
journal
20044
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"