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Annals of Thoracic Surgery

Sven M Almdahl, Petter Cappelen Endresen
No abstract text is available yet for this article.
September 15, 2018: Annals of Thoracic Surgery
Jonathan D Spicer, Jitesh B Shewale, David B Nelson, Kyle G Mitchell, Matthew J Bott, Eric Vallières, Candice L Wilshire, Ara A Vaporciyan, Stephen G Swisher, David R Jones, Gail E Darling, Boris Sepesi
BACKGROUND: Induction chemoradiation for resectable N2 non-small cell lung cancer (NSCLC) is used with the intent to optimize locoregional control, whereas induction chemotherapy given in systemic doses is meant to optimally target potential distant disease. However, the optimal preoperative treatment regimen is still unknown and practice patterns continue to vary widely. We compared multi-institutional oncologic outcomes for N2 NSCLC from four experienced lung cancer treatment centers...
September 15, 2018: Annals of Thoracic Surgery
Sean M O'Brien, Jeffrey P Jacobs, David M Shahian, Marshall L Jacobs, J William Gaynor, Jennifer C Romano, Michael G Gaies, Kevin D Hill, John E Mayer, Sara K Pasquali
BACKGROUND: We describe the statistical methods and results related to development of the first congenital heart surgery composite quality measure. METHODS: The composite measure was developed using the Society of Thoracic Surgeons (STS) Congenital Heart Surgery Database (2012-2015), Bayesian hierarchical modeling, and the current STS risk model for case-mix adjustment. It is comprised of a mortality domain (operative mortality), and morbidity domain [major complications, and post-operative length of stay (LOS)]...
September 15, 2018: Annals of Thoracic Surgery
Sara K Pasquali, David M Shahian, Sean M O'Brien, Marshall L Jacobs, J William Gaynor, Jennifer C Romano, Michael G Gaies, Kevin D Hill, John E Mayer, Jeffrey P Jacobs
BACKGROUND: Current pediatric and congenital heart surgery quality measures focus on operative mortality, and numerous stakeholders are interested in more comprehensive measures. This report describes the background, rationale, and conceptual framework related to the development of the first composite quality metric in the field. METHODS: A multidisciplinary panel reviewed methodology and framework related to quality measurement and several composite quality measures across adult cardiac surgery other fields...
September 15, 2018: Annals of Thoracic Surgery
Niraj Nirmal Pandey, Arun Sharma, Kehkashan Chowhan, Priya Jagia
No abstract text is available yet for this article.
September 15, 2018: Annals of Thoracic Surgery
Masashi Mikubo, Masahito Naito, Yoshio Matsui, Kazu Shiomi, Masaaki Ichinoe, Tsutomu Yoshida, Yukitoshi Satoh
BACKGROUND: The association between pleural lavage cytology (PLC) and histological subtype remains unknown. In this study, we aimed to evaluate the impact of a micropapillary pattern (MPP) in lung adenocarcinomas on results of PLC. METHODS: We retrospectively reviewed 600 consecutive patients with surgically resected pulmonary adenocarcinomas and investigated the relationship between PLC status and clinicopathological factors, including a histologically identified MPP component...
September 15, 2018: Annals of Thoracic Surgery
Christopher R Morse
No abstract text is available yet for this article.
September 14, 2018: Annals of Thoracic Surgery
Thomas H Shin, Elica Inagaki, Teja Ganta, Kevan Hartshorn, Virginia R Litle, Kei Suzuki
Tumor lysis syndrome (TLS) is a life-threatening complication comprised of hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia attributed to release of intracellular contents. While traditionally associated with leukemia and lymphoma after chemotherapy, it is known to occur in solid malignancies. We herein report a rare case of this syndrome after resection of bulky carcinoid tumor of the lung.
September 12, 2018: Annals of Thoracic Surgery
Pei-Hsing Chen, Hsao-Hsun Hsu, Shun-Mao Yang, Tung-Ming Tsai, Kuan-Chuan Tsou, Hsien-Chi Liao, Mong-Wei Lin, Jin-Shing Chen
BACKGROUND: Preoperative computed tomography (CT)-guided dye localization is essential for the surgical treatment of small lung nodules and is mostly performed by radiologists in the CT room. Several studies reported their early experiences of preoperative localization in the hybrid operating room. A comparison between localization in the CT and hybrid rooms has not been reported. Therefore, we compared the outcomes of preoperative localization in the hybrid and CT rooms. METHODS: This study included patients who underwent preoperative CT-guided dye localization for thoracoscopic lung tumor surgery in the hybrid operation (n=25) and CT (n=283) rooms at our institute...
September 12, 2018: Annals of Thoracic Surgery
Jessica M Mayor, Donald R Lazarus, Roberto F Casal, Shuab Omer, Ourania Preventza, Katherine Simpson, Ernesto Jimenez, Lorraine D Cornwell
BACKGROUND: Air leaks can impede recovery from lung resection. To help prevent and manage air leaks, we developed a comprehensive program that includes using precompression of lung staple lines, sealant, fissure-less video-assisted thoracoscopic (VATS) lobectomy, a digital-drainage system, and endobronchial valve placement for prolonged air leak. We assessed the effect of this program on prolonged air leaks, hospital length of stay (LOS), and chest tube days in our high-risk veteran population...
September 12, 2018: Annals of Thoracic Surgery
Yuki Ikeno, Yojiro Koda, Koki Yokawa, Yasuko Gotake, Soichiro Henmi, Hidekazu Nakai, Takashi Matsueda, Takeshi Inoue, Hiroshi Tanaka, Yutaka Okita
BACKGROUND: The study aimed to evaluate the early and long-term outcomes following graft replacement of Kommerell's diverticulum and in-situ reconstruction of aberrant subclavian arteries in adults. METHODS: Seventeen patients, of whom 6 patients were symptomatic and 11 had right aortic arch, underwent open repair of Kommerell's diverticulum from October 1999 to September 2017. Two of these patients underwent open surgery for a ruptured aneurysm. Indications for surgery were dilatation of Kommerell's aneurysm (n = 9), presence of a non-dissecting aneurysm with Kommerell's diverticulum (n = 6), acute type A aortic dissection (n = 1), and complicated acute type B aortic dissection (n = 1)...
September 12, 2018: Annals of Thoracic Surgery
Mark K Ferguson, Jeanne Farnan, Kristen Wroblewski, Megan Huisingh-Scheetz, Katherine Thompson
BACKGROUND: Clinical vignettes are frequently used as instructional and evaluative instruments for physicians. Physician gender is a source of unconscious bias in treatment recommendations. We assessed whether interpretation of information in clinical vignettes differs by physician gender as a possible source of unconscious bias. METHODS: Thoracic surgeons and physicians in cardiothoracic surgical training were asked to provide estimates of major complication rates for lung resection based on anonymized clinical vignettes of lung resection patients...
September 8, 2018: Annals of Thoracic Surgery
Hironori Ishibashi, Ryo Wakejima, Chihiro Takasaki, Kenichi Okubo
Cellular schwannoma is a rare variant of schwannoma showing high cellularity and a low mitotic index. A 64-year-old man was admitted to our hospital with a 2-month history of productive cough. Chest computed tomography showed an endobronchial tumor with complete atelectasis of the right lower lobe. Bronchoscopy showed an endobronchial tumor occluding the intermediate bronchus that was diagnosed as a cellular schwannoma on biopsy and successfully excised with a right lower sleeve lobectomy to preserve the middle lobe...
September 8, 2018: Annals of Thoracic Surgery
Zhe Xu, Shu-Yu Zhang, Min Huang, Rong Hu, Jia-Li Li, Han-Jin Cen, Zhi-Ping Wang, Jing-Song Ou, Sheng-Li Yin, Ying-Qi Xu, Zhong-Kai Wu, Xi Zhang
BACKGROUND: The clinical utility of genotype-guided warfarin dosing remains controversial. The objective of this trial was to evaluate the efficacy and safety of genotype-guided warfarin dosing in East Asians. METHODS: A double-blind, randomized control trial was performed to compare a genotype-guided dosing algorithm (CYP2C9, VKORC1 and CYP4F2) with a clinical-guided one in the initiation treatment for patients with mechanical heart valves. The primary outcomes included the time to reach a stable dose and the percentage of time in the therapeutic range (TTR)...
September 8, 2018: Annals of Thoracic Surgery
Melanie R F Gropler, Bradley S Marino, Michael R Carr, William W Russell, Hongjie Gu, Osama M Eltayeb, Michael C Mongé, Carl L Backer
BACKGROUND: Optimal surgical approach for repair of coarctation of the aorta (CoA) remains controversial. This study aims to evaluate reintervention rates and its predictors using a strategy of resection with extended end-to-end anastomosis (REEEA) via left thoracotomy. METHODS: A retrospective analysis was performed for all patients who underwent isolated CoA repair or CoA and simultaneous VSD repair via REEEA between Jan 2000-Dec 2015. Patients with complex congenital heart disease were excluded...
September 8, 2018: Annals of Thoracic Surgery
Mauricio A Villavicencio, Andrea L Axtell, Philip J Spencer, Elbert E Heng, Sumner Kilmarx, Nina Dalpozzal, Masaki Funamoto, Nathalie Roy, Asishana Osho, Serguei Melnitchouk, David A D'Alessandro, George Tolis, Todd Astor
BACKGROUND: Lung transplants from Donors after Circulatory Death (DCD) have been scarcely used in the United States. Concerns about the warm ischemic injury, resource mal-utilization due to the uncertain timing of death, and public scrutiny may be some factors involved. METHODS: Survival for recipients of a Donation after Brain Death (DBD) versus DCD was analyzed using the UNOS and our institutional database. A propensity-matching and Cox regression analysis was performed for 25 characteristics...
September 8, 2018: Annals of Thoracic Surgery
Max Jordan Nguemeni Tiako, Makoto Mori, Arnar Geirsson
No abstract text is available yet for this article.
September 4, 2018: Annals of Thoracic Surgery
Michael Ried, Laura Sommerauer, Matthias Lubnow, Thomas Müller, Alois Philipp, Dirk Lunz, Hans-Stefan Hofmann
BACKGROUND: Patients with respiratory failure are treated more frequently with veno-venous extracorporeal membrane oxygenation (vv-ECMO). These patients are at risk for bleeding due to complex multifactorial coagulation disorders resulting from the extracorporeal circulation. METHODS: Retrospective analysis of prospectively collected data on all patients requiring vv-ECMO between December 2010 and December 2016. Endpoints were the incidence, consequence and in-hospital mortality of patients with thoracic bleeding complications...
September 4, 2018: Annals of Thoracic Surgery
Samer Kassem, Maurizio Roberto, Gabriella Ricciardi, Francesco Alamanni
We describe an approach to address the left ventricular outflow tract obstruction (LVOTO) in Hypertrophic Obstructive Cardiomyopathy (HOCM) with concomitant systolic anterior motion of mitral valve. This approach has two main purposes: to enlarge the LVOT through a "moderate" myectomy and to "discipline" the excessive movement of the mitral valve anterior leaflet through paradoxical chords implantation(2,3) and, similarly, the papillary muscle too, if necessary, hanging paradoxical chords between the papillary muscle itself and the posterior mitral annulus(5) ...
September 4, 2018: Annals of Thoracic Surgery
Katsuhiro Yamanaka, Mohamed Eldeiry, Muhammad Aftab, Thomas J Ryan, Joshua Mares, Xianzhong Meng, Michael J Weyant, Joseph C Cleveland, David A Fullerton, T Brett Reece
BACKGROUND: Paraplegia remains a devastating complication of thoracoabdominal aortic intervention. Metabolic stress induces expression of Beta Common Receptor subunit of erythropoietin (EPO) receptor (bcR) to exert a neuroprotective effect in spinal cord ischemia reperfusion injury (SCIR). Diazoxide (DZ) has been shown to induce ischemic tolerance. We previously reported that DZ upregulated bcR expression, and DZ enhanced the neuroprotective effects of EPO through the upregulation of bcR...
September 4, 2018: Annals of Thoracic Surgery
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