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Annals of Surgery

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https://www.readbyqxmd.com/read/28221166/prevalence-of-needlestick-injuries-attitude-changes-and-prevention-practices-over-12-years-in-an-urban-academic-hospital-surgery-department
#1
Jessica M Hasak, Christine B Novak, Jennifer Megan M Patterson, Susan E Mackinnon
OBJECTIVE: Needlestick injury prevalence, protection practices, and attitudes were assessed. Current medical students were compared with 2003 data to assess any changes that occurred with engineered safety feature implementation. BACKGROUND: Risk of occupational exposure to bloodborne pathogens is elevated in the operating room particularly with surgeons in training and nurses. METHODS: A cross-sectional survey was distributed to medical students (n = 358) and Department of Surgery staff (n = 247)...
February 17, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28207436/multicenter-observational-study-of-adhesion-formation-after-open-and-laparoscopic-surgery-for-colorectal-cancer
#2
Martijn W J Stommel, Richard P G Ten Broek, Chema Strik, Gerrit D Slooter, Cornelis Verhoef, Dirk J Grünhagen, Peter van Duijvendijk, Marc H A Bemelmans, Marcel den Dulk, Colin Sietses, Tjarda N T van Heek, Peter B van den Boezem, Johannes H W de Wilt, Harry van Goor
OBJECTIVE: The aim of this study was to compare adhesion formation after laparoscopic and open colorectal cancer resection. SUMMARY OF BACKGROUND DATA: After colorectal surgery, most patients develop adhesions, with a high burden of complications. Laparoscopy seems to reduce adhesion formation, but evidence is poor. Trials comparing open- and laparoscopic colorectal surgery have never assessed adhesion formation. METHODS: Data on adhesions were gathered during resection of colorectal liver metastases...
February 15, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28187045/apolipoprotein-l1-and-chronic-kidney-disease-risk-in-young-potential-living-kidney-donors
#3
Jayme E Locke, Deirdre Sawinski, Rhiannon D Reed, Brittany Shelton, Paul A MacLennan, Vineeta Kumar, Shikha Mehta, Roslyn B Mannon, Robert Gaston, Bruce A Julian, John J Carr, James G Terry, Meredith Kilgore, Allan B Massie, Dorry L Segev, Cora E Lewis
OBJECTIVE: The aim of this study was to develop a novel chronic kidney disease (CKD) risk prediction tool for young potential living kidney donors. SUMMARY OF BACKGROUND DATA: Living kidney donor selection practices have evolved from examining individual risk factors to a risk calculator incorporating multiple characteristics. Owing to limited long-term data and lack of genetic information, current risk tools lack precision among young potential living kidney donors, particularly African Americans (AAs)...
February 9, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28187044/minimally-invasive-versus-open-esophageal-resection-three-year-follow-up-of-the-previously-reported-randomized-controlled-trial-the-time-trial
#4
Jennifer Straatman, Nicole van der Wielen, Miguel A Cuesta, Freek Daams, Josep Roig Garcia, Luigi Bonavina, Camiel Rosman, Mark I van Berge Henegouwen, Suzanne S Gisbertz, Donald L van der Peet
OBJECTIVE: The aim of this study was to investigate 3-year survival following a randomized controlled trial comparing minimally invasive with open esophagectomy in patients with esophageal cancer. BACKGROUND: Research on minimally invasive esophagectomy (MIE) has shown faster postoperative recovery and a marked decrease in pulmonary complications. Debate is ongoing as to whether the procedure is equivalent to open resection regarding oncologic outcomes. The study is a follow-up study of the TIME-trial (traditional invasive vs minimally invasive esophagectomy, a multicenter, randomized trial)...
February 9, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28187043/difficulty-of-laparoscopic-liver-resection-proposal-for-a-new-classification
#5
Yoshikuni Kawaguchi, David Fuks, Norihiro Kokudo, Brice Gayet
OBJECTIVE: We propose an objective and practical classification system to predict difficulty of different laparoscopic liver resections (LLRs). BACKGROUND: Surgical difficulty is highly subjective and is not influenced only by surgical factors. Consequently, few series have described the degree of difficulty of LLR or attempted to objectively assess the surgical difficulty. METHODS: From a prospectively maintained database between 1995 and 2015, patients undergoing LLR without simultaneous procedures were selected, and LLR procedures were divided into 3 groups according to scores based on operative time (< or ≥190 minutes), blood loss (< or ≥100 mL), and conversion rate (< or ≥4...
February 9, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28187042/can-methicillin-resistant-staphylococcus-aureus-silently-travel-from-the-gut-to-the-wound-and-cause-postoperative-infection-modeling-the-trojan-horse-hypothesis
#6
Monika A Krezalek, Sanjiv Hyoju, Alexander Zaborin, Emeka Okafor, Laxmi Chandrasekar, Vitas Bindokas, Kristina Guyton, Christopher P Montgomery, Robert S Daum, Olga Zaborina, Susan Boyle-Vavra, John C Alverdy
OBJECTIVE: To determine whether intestinal colonization with methicillin-resistant Staphylococcus aureus (MRSA) can be the source of surgical site infections (SSIs). BACKGROUND: We hypothesized that gut-derived MRSA may cause SSIs via mechanisms in which circulating immune cells scavenge MRSA from the gut, home to surgical wounds, and cause infection (Trojan Horse Hypothesis). METHODS: MRSA gut colonization was achieved by disrupting the microbiota with antibiotics, imposing a period of starvation and introducing MRSA via gavage...
February 9, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28187041/laparoscopy-assisted-versus-open-d2-distal-gastrectomy-for-advanced-gastric-cancer-results-from-a-randomized-phase-ii-multicenter-clinical-trial-coact-1001
#7
Young Kyu Park, Hong Man Yoon, Young-Woo Kim, Ji Yeon Park, Keun Won Ryu, Young-Joon Lee, Oh Jeong, Ki Young Yoon, Jun Ho Lee, Sang Eok Lee, Wansik Yu, Sang-Ho Jeong, Taebong Kim, Sohee Kim, Byoung-Ho Nam
OBJECTIVE: This randomized, phase II, multicenter clinical trial was conducted to evaluate the feasibility of laparoscopy-assisted distal gastrectomy (LADG) with D2 lymph node dissection compared with open distal gastrectomy (ODG) for the treatment of advanced gastric cancer (AGC). SUMMARY OF BACKGROUND DATA: D2 lymph node dissection has been accepted as standard treatment for AGC. Although LADG is widely performed in early gastric cancer (EGC), the feasibility of LADG in AGC has not been proven yet...
February 9, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28181939/real-time-navigation-for-liver-surgery-using-projection-mapping-with-indocyanine-green-fluorescence-development-of-the-novel-medical-imaging-projection-system
#8
Hiroto Nishino, Etsuro Hatano, Satoru Seo, Takashi Nitta, Tomoyuki Saito, Masaaki Nakamura, Kayo Hattori, Muneo Takatani, Hiroaki Fuji, Kojiro Taura, Shinji Uemoto
OBJECTIVE: The aim of the present study was to evaluate the usefulness of a new imaging device, the Medical Imaging Projection System (MIPS), which uses the indocyanine green emission signal and active projection mapping, for liver resection. BACKGROUND: During anatomic liver resection, surgeons cannot completely view the intraparenchymal structure. Although a fluorescent imaging technique using indocyanine green has recently been developed for hepatobiliary surgery, limitations in its application for real-time navigation persist...
February 8, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28169837/survival-outcomes-for-patients-with-indeterminate-18fdg-pet-scan-for-extrahepatic-disease-before-liver-resection-for-metastatic-colorectal-cancer-a-retrospective-cohort-study-using-a-prospectively-maintained-database-to-analyze-survival-outcomes-for-patients
#9
Geoffrey Yuet Mun Wong, Rajiv Kumar, Carol Beeke, Shahid Ullah, John Chen, Christos Karapetis, Timothy Price, Rob Padbury
OBJECTIVE: The aim of this study was to evaluate overall survival (OS) and cancer recurrence for patients with indeterminate positron emission tomography (PET) scan for extrahepatic disease (EHD) before liver resection (LR) for colorectal liver metastases (CLMs). SUMMARY OF BACKGROUND DATA: Indeterminate EHD as determined by PET imaging indicates a probability of extrahepatic malignancy and potentially excludes patients from undergoing LR for CLM. METHODS: In a retrospective analysis of prospectively collected data from February 2006 to December 2014, OS for patients with indeterminate EHD on FDG-PET scan before LR for CLM was performed using standard survival analysis methods, including Kaplan-Meier estimator and Cox proportional hazard models for multivariate analyses...
February 6, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28166091/oral-polyphosphate-suppresses-bacterial-collagenase-production-and-prevents-anastomotic-leak-due-to-serratia-marcescens-and-pseudomonas-aeruginosa
#10
Sanjiv K Hyoju, Robin E Klabbers, Melissa Aaron, Monika A Krezalek, Alexander Zaborin, Mara Wiegerinck, Neil H Hyman, Olga Zaborina, Harry Van Goor, John C Alverdy
OBJECTIVE: The objective of this study was to determine the effect of polyphosphate on intestinal bacterial collagenase production and anastomotic leak in mice undergoing colon surgery. BACKGROUND: We have previously shown that anastomotic leak can be caused by intestinal pathogens that produce collagenase. Because bacteria harbor sensory systems to detect the extracellular concentration of phosphate which controls their virulence, we tested whether local phosphate administration in the form of polyphosphate could attenuate pathogen virulence and prevent leak without affecting bacterial growth...
February 3, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28221165/response-to-letter-comment-on-insurance-status-not-race-is-associated-with-use-of-minimally-invasive-surgical-approach-for-rectal-cancer
#11
Megan C Turner, Mohamed Abdelgadir Adam, Zhifei Sun, Jina Kim, Brian Ezekian, Babatunde A Yerokun, Christopher R Mantyh, John Migaly
No abstract text is available yet for this article.
February 1, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28151803/sex-differences-in-civilian-injury-in-baghdad-from-2003-to-2014-results-of-a-randomized-household-cluster-survey
#12
Kyle Shaak, Riyadh Lafta, Barclay T Stewart, Thomas R Fowler, Sahar A Esa Al-Shatari, Gilbert Burnham, Megan Cherewick, Sherry M Wren, Reinou S Groen, Adam L Kushner
OBJECTIVE: To examine sex differences in injury mechanisms, injury-related death, injury-related disability, and associated financial consequences in Baghdad since the 2003 invasion of Iraq to inform prevention initiatives, health policy, and relief planning. BACKGROUND: Reliable estimates of injury burden among civilians during conflict are lacking, particularly among vulnerable subpopulations, such as women. METHODS: A 2-stage, cluster randomized, community-based household survey was conducted in May 2014 to determine the civilian burden of injury in Baghdad since 2003...
February 1, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28151802/erythropoietin-to-reduce-mortality-in-traumatic-brain-injury-a-post-hoc-dose-effect-analysis
#13
Dashiell C Gantner, Michael Bailey, Jeffrey Presneill, Craig J French, Alistair Nichol, Lorraine Little, Rinaldo Bellomo
OBJECTIVE: We aimed to assess whether the dosing regimen of erythropoietin shows a relationship to mortality in critically ill patients with traumatic brain injury (TBI). BACKGROUND: Erythropoietin may decrease mortality in patients with TBI; however, the optimal dosing regimen remains uncertain. METHODS: We conducted a post-hoc analysis of a multicenter, randomized trial of weekly erythropoietin versus placebo in patients with moderate and severe TBI admitted to intensive care...
February 1, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28151801/accuracy-of-clinical-staging-and-outcome-with-primary-resection-for-local-regionally-limited-esophageal-adenocarcinoma
#14
Stephanie G Worrell, Evan T Alicuben, Daniel S Oh, Jeffrey A Hagen, Steven R DeMeester
OBJECTIVE: The aim of this study was to determine the accuracy of clinical staging, to assess survival with surgical resection alone, and to determine factors associated with understaging in patients with esophageal adenocarcinoma thought to have limited local-regional disease. BACKGROUND: Primary surgical resection is the preferred treatment in patients with esophageal adenocarcinoma clinically staged to have limited nodal disease. This approach requires reliable clinical staging...
February 1, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28151800/comparative-effectiveness-and-risks-of-bowel-preparation-before-elective-colorectal-surgery
#15
Sarah E Koller, Katherine W Bauer, Brian L Egleston, Radhika Smith, Matthew M Philp, Howard M Ross, Nestor F Esnaola
OBJECTIVE: The objective of this study was to determine the relationship between bowel preparation and surgical site infections (SSIs), and also other postoperative complications, after elective colorectal surgery. BACKGROUND: SSI is a major source of postoperative morbidity/costs after colorectal surgery. The value of preoperative bowel preparation to prevent SSI remains controversial. METHODS: We analyzed 32,359 patients who underwent elective colorectal resections in the American College of Surgeons National Surgery Quality Improvement Program database from 2012 to 2014...
February 1, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28151799/survival-healthcare-utilization-and-end-of-life-care-among-older-adults-with-malignancy-associated-bowel-obstruction-comparative-study-of-surgery-venting-gastrostomy-or-medical-management
#16
Elizabeth J Lilley, John W Scott, Joel E Goldberg, Christy E Cauley, Jennifer S Temel, Andrew S Epstein, Stuart R Lipsitz, Brittany L Smalls, Adil H Haider, Angela M Bader, Joel S Weissman, Zara Cooper
OBJECTIVE: To compare survival, readmissions, and end-of-life care after palliative procedures compared with medical management for malignancy-associated bowel obstruction (MBO). BACKGROUND: MBO is a late complication of intra-abdominal malignancy for which surgeons are frequently consulted. Decisions about palliative treatments, which include medical management, surgery, or venting gastrostomy tube (VGT), are hampered by the paucity of outcomes data relevant to patients approaching the end of life...
February 1, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28151798/modulating-portal-hemodynamics-with-vascular-ring-allows-efficient-regeneration-after-partial-hepatectomy-in-a-porcine-model
#17
Petru O Bucur, Mohamed Bekheit, Chloe Audebert, Amnah Othman, Seddik Hammad, Mylene Sebagh, Marc-Antoine Allard, Benoît Decante, Adrian Friebel, Elodie Miquelestorena-Standley, Dirk Drasdo, Jan G Hengstler, Irene E Vignon-Clementel, Eric Vibert
OBJECTIVE: To investigate safety and efficacy of temporary portal hemodynamics modulation with a novel percutaneously adjustable vascular ring (MID-AVR) onto a porcine model of 75% hepatectomy. BACKGROUND: Postoperative liver failure is a leading cause of mortality after major hepatectomy. Portal flow modulation is an increasingly accepted concept to prevent postoperative liver failure. Nonetheless, the current strategies have shortcomings. METHODS: Resection was performed under hemodynamic monitoring in 17 large, white pigs allocated into 2 groups...
February 1, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28151797/laparoscopic-versus-open-liver-resection-for-colorectal-metastases-in-elderly-and-octogenarian-patients-a-multicenter-propensity-score-based-analysis-of-short-and-long-term-outcomes
#18
David Martínez-Cecilia, Federica Cipriani, Shelat Vishal, Francesca Ratti, Hadrien Tranchart, Leonid Barkhatov, Federico Tomassini, Roberto Montalti, Mark Halls, Roberto I Troisi, Ibrahim Dagher, Luca Aldrighetti, Bjorn Edwin, Mohammad Abu Hilal
OBJECTIVE: This study aims to compare the perioperative and oncological outcomes of laparoscopic and open liver resection for colorectal liver metastases in the elderly. BACKGROUND: Laparoscopic liver resection has been associated with less morbidity and similar oncological outcomes to open liver resection for colorectal liver metastases (CRLMs). It has been reported that these benefits continue to be observed in elderly patients. However, in previous studies, patients over 70 or 75 years were considered as a single, homogenous population raising questions regarding the true impact of the laparoscopic approach on this diverse group of elderly patients...
February 1, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28151796/clinical-and-prognostic-features-of-patients-with-esophageal-cancer-and-multiple-primary-cancers-a-retrospective-single-institution-study
#19
Yoshifumi Baba, Naoya Yoshida, Koichi Kinoshita, Masaaki Iwatsuki, Yo-Ichi Yamashita, Akira Chikamoto, Masayuki Watanabe, Hideo Baba
OBJECTIVE: To investigate the clinical and prognostic characteristics of patients with esophageal cancer and multiple primary cancers. SUMMARY BACKGROUND DATA: Patients with esophageal cancer frequently have multiple primary cancers, the presence of which may complicate physicians' decision-making because the clinical and prognostic features of such patients remain unknown. METHODS: This retrospective single-institution study included 538 consecutive patients who had undergone resection of esophageal cancer...
February 1, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28151795/effect-of-preoperative-opioid-exposure-on-healthcare-utilization-and-expenditures-following-elective-abdominal-surgery
#20
Jennifer F Waljee, David C Cron, Rena M Steiger, Lin Zhong, Michael J Englesbe, Chad M Brummett
OBJECTIVE: To examine the extent to which preoperative opioid use is correlated with healthcare utilization and costs following elective surgical procedures. SUMMARY BACKGROUND DATA: Morbidity and mortality associated with prescription opioid use is escalating in the United States. The extent to which chronic opioid use influences postoperative outcomes following elective surgery is not well understood. METHODS: Truven Health Marketscan Databases were used to identify adult patients who underwent elective abdominal surgery between June 2009 and December 2012 (n = 200,005)...
February 1, 2017: Annals of Surgery
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