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Annals of the Rheumatic Diseases

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https://www.readbyqxmd.com/read/29150425/amino-bisphosphonates-%C3%AE-%C3%AE-t-cells-and-their-roles-in-rheumatoid-arthritis
#1
Wen-Xiu Mo, Shan-Shan Yin, Hua Chen, Xuan Zhang
No abstract text is available yet for this article.
November 17, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29146746/response-to-the-value-of-18-f-fdg-pet-ct-in-identifying-the-cause-of-fever-of-unknown-origin-fuo-and-inflammation-of-unknown-origin-iuo-data-from-a-prospective-study
#2
Verena Schönau, Georg Schett
No abstract text is available yet for this article.
November 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29146745/response-to-use-of-urate-lowering-therapies-is-not-associated-with-an-increase-in-the-risk-of-incident-dementia-in-older-adults-by-lee-and-song
#3
Jasvinder A Singh, John Cleveland
No abstract text is available yet for this article.
November 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29146744/response-to-increased-stroke-incidence-in-systemic-lupus-erythematosus-patients-risk-factors-or-disease-itself-by-bruzzese-and-zullo
#4
Elizabeth V Arkema, Marios Rossides, Mia Von Euler, Elisabet Svenungsson, Christopher Sjöwall, Julia F Simard
No abstract text is available yet for this article.
November 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29146743/testing-treat-to-target-outcomes-with-initial-methotrexate-monotherapy-compared-with-initial-tumour-necrosis-factor-inhibitor-adalimumab-plus-methotrexate-in-early-rheumatoid-arthritis
#5
Arthur Kavanaugh, Ronald van Vollenhoven, Roy M Fleischmann, Paul Emery, Iain Sainsbury, Stefan Florentinus, Su Chen, Benoît Guérette, Hartmut Kupper, Josef S Smolen
OBJECTIVES: To compare responses in patients with early rheumatoid arthritis (RA) initially treated with the tumour necrosis factor inhibitor (TNFi) adalimumab+methotrexate (MTX) versus MTX monotherapy who may have continued receiving MTX or switched to adalimumab rescue therapy after inadequate response to MTX. METHODS: OPTIMA enrolled MTX-naive patients with active RA for <1 year. This post hoc analysis determined the proportion of patients, stratified by initial treatment, who achieved28-joint modified Disease Activity Score based on C reactive protein <3...
November 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29146742/cardiovascular-effects-of-hydroxychloroquine-a-systematic-review-and-meta-analysis
#6
LETTER
Young Ho Lee
No abstract text is available yet for this article.
November 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29146741/presence-of-monosodium-urate-crystal-deposition-by-dual-energy-ct-in-patients-with-gout-treated-with-allopurinol
#7
Nicola Dalbeth, Savvas Nicolaou, Scott Baumgartner, Jia Hu, Maple Fung, Hyon K Choi
OBJECTIVE: Dual-energy CT (DECT) detects and quantifies monosodium urate (MSU) crystal deposition with high precision. This DECT study assessed crystal deposition in patients with gout treated with stable-dose allopurinol, and investigated potential clinical determinants for crystal deposition. METHODS: Patients with gout treated with allopurinol ≥300 mg daily for at least 3 months were prospectively recruited from the USA and New Zealand, using monitored enrolment to include approximately 25% patients with palpable tophi and approximately 50% with serum urate (sUA) levels <6...
November 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29146740/validation-of-the-psoriatic-arthritis-impact-of-disease-psaid-questionnaire-and-its-potential-as-a-single-item-outcome-measure-in-clinical-practice
#8
Richard Holland, William Tillett, Eleanor Korendowych, Charlotte Cavill, Nicola Waldron, Melanie Brooke, Neil J McHugh
OBJECTIVES: The Psoriatic Arthritis Impact of Disease (PsAID) Questionnaire is a recently developed patient-reported outcome measure (PROM) of disease impact in psoriatic arthritis (PsA). We set out to assess the validity in an independent cohort of patients, estimate the minimally important difference for improvement and explore the potential of individual components of the PsAID in clinical practice. METHODS: Data were collected prospectively for a single-centre cohort of patients with PsA...
November 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29146739/utility-of-pet-ct-in-the-diagnosis-of-inflammatory-rheumatic-diseases-a-systematic-review-and-meta-analysis
#9
LETTER
Lucie Descamps, Louis Olagne, Charles Merlin, Florent Cachin, Martin Soubrier, Sylvain Mathieu
No abstract text is available yet for this article.
November 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29146738/response-to-eletter-cardiovascular-effects-of-hydroxychloroquine-a-systematic-review-and-meta-analysis-by-mathieu-et-al
#10
Charlotte Hua, Claire Rempenault, Bernard Combe
No abstract text is available yet for this article.
November 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29146737/rheumatic-disorders-associated-with-immune-checkpoint-inhibitors-in-patients-with-cancer-clinical-aspects-and-relationship-with-tumour-response-a-single-centre-prospective-cohort-study
#11
Marie Kostine, Léa Rouxel, Thomas Barnetche, Rémi Veillon, Florent Martin, Caroline Dutriaux, Léa Dousset, Anne Pham-Ledard, Sorilla Prey, Marie Beylot-Barry, Amaury Daste, Marine Gross-Goupil, Julie Lallier, Alain Ravaud, Edouard Forcade, Bernard Bannwarth, Marie-Elise Truchetet, Christophe Richez, Nadia Mehsen, Thierry Schaeverbeke
OBJECTIVES: To evaluate the prevalence and type of rheumatic immune-related adverse events (irAEs) in patients receiving immune checkpoint inhibitors (ICIs), as well as the correlation with tumour response. METHODS: This was a single-centre prospective observational study including all cancer patients receiving ICIs. The occurrence of irAEs and tumour response was assessed on a regular basis. Patients who experienced musculoskeletal symptoms were referred to the department of rheumatology for clinical evaluation and management...
November 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29138257/clinical-juvenile-arthritis-disease-activity-score-proves-to-be-a-useful-tool-in-treat-to-target-therapy-in-juvenile-idiopathic-arthritis
#12
Joost F Swart, E H Pieter van Dijkhuizen, Nico M Wulffraat, Sytze de Roock
OBJECTIVES: To assess if the Juvenile Arthritis Disease Activity Score (JADAS71) could be used to correctly identify patients with juvenile idiopathic arthritis (JIA) in need of antitumour necrosis factor therapy (anti-TNF) therapy 3 and 6 months after start of methotrexate (MTX). METHODS: Monocentric retrospective cohort study from 2011 to 2015 analysing all patients with oligoarticular JIA (OJIA) (n=39) and polyarticular course JIA (PJIA) (n=74) first starting MTX...
November 14, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29133476/response-to-uric-acid-and-incident-dementia-a-population-based-cohort-study-by-lee-and-song
#13
Augustin Latourte, Aicha Soumaré, Thomas Bardin, Stéphanie Debette, Pascal Richette
No abstract text is available yet for this article.
November 13, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29133475/response-to-comment-on-l-ami-et-al-titled-successful-reduction-of-overexposure-in-patients-with-rheumatoid-arthritis-with-high-serum-adalimumab-concentrations-an-open-label-non-inferiority-randomised-clinical-trial-by-den-broeder-et-al
#14
Merel J l'Ami, Charlotte L M Krieckaert, Michael T Nurmohamed, Ronald F van Vollenhoven, Theo Rispens, Maarten Boers, Gerrit Jan Wolbink
No abstract text is available yet for this article.
November 13, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29127094/use-of-urate-lowering-therapies-is-not-associated-with-an-increased-risk-of-incident-dementia-in-older-adults
#15
LETTER
Young Ho Lee, Gwan Gyu Song
No abstract text is available yet for this article.
November 10, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29127093/development-of-the-ct-syndesmophyte-score-ctss-in-patients-with-ankylosing-spondylitis-data-from-the-sias-cohort
#16
Freek de Bruin, Anoek de Koning, Rosaline van den Berg, Xenofon Baraliakos, Juergen Braun, Sofia Ramiro, Floris A van Gaalen, Monique Reijnierse, Désirée van der Heijde
OBJECTIVES: To develop the CT Syndesmophyte Score (CTSS) for low-dose CT (ldCT) to assess structural damage in the spine of patients with ankylosing spondylitis (AS) and test its reliability. METHODS: Patientswith AS in the SIAS cohort had whole spine ldCT at baseline and 2 years. Syndesmophytes were scored in coronal and sagittal planes in eight quadrants per vertebral unit (VU) as absent=0, <50% of the intervertebral disc space (IDS)=1, ≥50%=2 or bridging the IDS=3 (range 0-552)...
November 10, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29127092/low-dose-ct-detects-more-progression-of-bone-formation-in-comparison-to-conventional-radiography-in-patients-with-ankylosing-spondylitis-results-from-the-sias-cohort
#17
Anoek de Koning, Freek de Bruin, Rosaline van den Berg, Sofia Ramiro, Xenofon Baraliakos, Juergen Braun, Floris A van Gaalen, Monique Reijnierse, Désirée van der Heijde
OBJECTIVES: To compare the CT Syndesmophyte Score (CTSS) for low-dose CT (ldCT) with the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) for conventional radiographs (CR) in patients with ankylosing spondylitis (AS). METHODS: Patients with AS in the Sensitive Imaging in Ankylosing Spondylitis cohort had lateral cervical and lumbar spine CR and whole spine ldCT at baseline and 2 years. CR and ldCT images were scored by two readers, paired by patient, blinded to time order, per imaging modality...
November 10, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29102958/acquiring-new-n-glycosylation-sites-in-variable-regions-of-immunoglobulin-genes-by-somatic-hypermutation-is-a-common-feature-of-autoimmune-diseases
#18
LETTER
Annie Visser, Nishath Hamza, Frans G M Kroese, Nicolaas A Bos
No abstract text is available yet for this article.
November 4, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29102957/stepwise-dose-increase-of-febuxostat-is-comparable-with-colchicine-prophylaxis-for-the-prevention-of-gout-flares-during-the-initial-phase-of-urate-lowering-therapy-results-from-fortune-1-a-prospective-multicentre-randomised-study
#19
Hisashi Yamanaka, Shigenori Tamaki, Yumiko Ide, Hyeteko Kim, Kouichi Inoue, Masayuki Sugimoto, Yuji Hidaka, Atsuo Taniguchi, Shin Fujimori, Tetsuya Yamamoto
OBJECTIVES: To determine whether febuxostat with stepwise dose increase is as useful as colchicine prophylaxis in reducing gout flares during the initial introduction of urate-lowering therapy in patients with gout in comparison with febuxostat with no dose titration. METHODS: In this prospective, multicentre, randomised open-label comparative study, patients were randomised to group A (stepwise dose increase of febuxostat from 10 to 40 mg/day), group B (fixed-dose febuxostat 40 mg/day plus colchicine 0...
November 4, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29102956/smoking-paradox-in-the-development-of-psoriatic-arthritis-among-patients-with-psoriasis-a-population-based-study
#20
Uyen-Sa D T Nguyen, Yuqing Zhang, Na Lu, Qiong Louie-Gao, Jingbo Niu, Alexis Ogdie, Joel M Gelfand, Michael P LaValley, Maureen Dubreuil, Jeffrey A Sparks, Elizabeth W Karlson, Hyon K Choi
OBJECTIVES: Smoking is associated with an increased risk of psoriatic arthritis (PsA) in the general population, but not among patients with psoriasis. We sought to clarify the possible methodological mechanisms behind this paradox. METHODS: Using 1995-2015 data from The Health Improvement Network, we performed survival analysis to examine the association between smoking and incident PsA in the general population and among patients with psoriasis. We clarified the paradox using mediation analysis and conducted bias sensitivity analyses to evaluate the potential impact of index event bias and quantify its magnitude from uncontrolled/unmeasured confounders...
November 4, 2017: Annals of the Rheumatic Diseases
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