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Annals of Otology, Rhinology, and Laryngology

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https://www.readbyqxmd.com/read/28205447/the-hybrid-transoral-pharyngotomy-approach-to-oropharyngeal-carcinoma
#1
Parul Sinha, Patrik Pipkorn, Joseph Zenga, Bruce H Haughey
BACKGROUND: The indications, techniques, and outcomes for a minimally invasive surgical approach in oropharyngeal squamous cell carcinoma (OPSCC) unsuitable for transoral resection are not well-described. METHODS: A retrospective case series was performed using a prospectively assembled database of transoral surgery-treated OPSCC patients who also underwent a "hybrid" approach of combined transoral and limited pharyngotomy for tumor resection. Disease and functional outcomes were evaluated...
February 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28177264/gender-disparities-in-speech-evoked-auditory-brainstem-response-in-healthy-adults
#2
Bahram Jalaei, Mohd Normani Zakaria, Mohd Hafiz Afifi Mohd Azmi, Nik Adilah Nik Othman, Dinsuhaimi Sidek
OBJECTIVES: Gender disparities in speech-evoked auditory brainstem response (speech-ABR) outcomes have been reported, but the literature is limited. The present study was performed to further verify this issue and determine the influence of head size on speech-ABR results between genders. METHODS: Twenty-nine healthy Malaysian subjects (14 males and 15 females) aged 19 to 30 years participated in this study. After measuring the head circumference, speech-ABR was recorded by using synthesized syllable /da/ from the right ear of each participant...
February 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28176544/self-directed-learning-in-otolaryngology-residents-preparation-for-surgical-cases
#3
Jad Jabbour, Anna Bakeman, Thomas Robey, Noel Jabbour
OBJECTIVES: To characterize the nature of surgical preparation among otolaryngology residents nationwide, determine the self-rated effectiveness and efficiency of case preparation practices, and identify potential means for educational improvement. METHODS: A survey examining the study objectives was developed and distributed to otolaryngology residents nationwide. Survey response data were submitted to descriptive analysis and comparative analyses between junior and senior residents...
February 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28103701/metformin-prevents-the-progression-of-dysplastic-mucosa-of-the-head-and-neck-to-carcinoma-in-nondiabetic-patients
#4
Michael Zvi Lerner, Niv Mor, Hyung Paek, Andrew Blitzer, Marshall Strome
OBJECTIVE: Metformin is an oral anti-hyperglycemic agent used to treat type 2 diabetes mellitus (DM). In vitro and animal models have shown that metformin can prevent the progression of oral lesions to carcinoma; however, there is conflicting data in the clinical literature regarding risk reduction for malignancy in head and neck cancer (HNC). STUDY DESIGN: Case series. METHODS: We present 3 cases in which adjuvant metformin therapy was used to treat recurrent and multifocal dysplastic lesions in previously treated nondiabetic HNC patients...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28103698/histamine-applied-topically-to-the-nasal-mucosa-increases-the-transmucosal-nitrous-oxide-exchange-for-the-middle-ear
#5
Miriam S Teixeira, Cuneyt M Alper, Brian S Martin, Selma Cetin, Jenna A El-Wagaa, William J Doyle
OBJECTIVE: Determine if the middle ear transmucosal nitrous oxide (N2O) exchange rate is affected by nasal inflammation caused by topical application of histamine. METHODS: In a randomized, double-blind, crossover study, 20 adults were challenged intranasally with histamine (5 mg) and placebo on separate occasions. At each session, the subjects were fitted with a non-rebreathing mask and breathed room air for 20 minutes, 50% N2O:50% O2 for 20 minutes, and 100% O2 for 10 minutes...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28100072/trial-vocal-fold-injection-predicts-thyroplasty-outcomes-in-nonparalytic-glottic-incompetence
#6
Lukas D Dumberger, Lewis Overton, Robert A Buckmire, Rupali N Shah
OBJECTIVES: Trial vocal fold injection (TVFI) may be used prior to permanent medialization when voice outcome is uncertain. We aimed to determine whether voice outcomes of TVFI are predictive of, or correlate with outcomes after type I Gore-Tex medialization thyroplasty (GMT) in patients with nonparalytic glottic incompetence (GI). METHODS: Thirty-five patients with nonparalytic GI who underwent TVFI followed by GMT were retrospectively reviewed. Change in voice-related quality of life (VRQOL) after TVFI was compared to change in VRQOL 3 to 9 months after GMT...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28092970/surgery-of-anterior-skull-base-lesions-in-children
#7
Thomas Karl Hoffmann, Marc Oliver Scheithauer, Fabian Sommer, Jörg Lindemann, Ernst-Johannes Haberl, Ulrike Friebe-Hoffmann, Marie-Nicole Theodoraki
INTRODUCTION: Lesions affecting the anterior skull base represent a rare group of craniofacial pathologies. A tumor of the facial midline, meningitis, or rhinoliquorrhea may be indicative of malformations like dermoid cysts, gliomas, encephaloceles, or nasal fistulas. METHODS: We present a case series of 13 children (4 months to 12 years; 8 males, 5 females) with lesions involving the anterior skull base, which were treated surgically in an interdisciplinary setting...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28073299/the-changing-impact-of-gastroesophageal-reflux-disease-in-clinical-practice
#8
Lee M Akst, Omar J Haque, John O Clarke, Alexander T Hillel, Simon R A Best, Kenneth W Altman
OBJECTIVES: The National Ambulatory Medical Care Survey (NAMCS) database was utilized to understand evolving national trends in diagnosis and management of reflux. METHODS: The NAMCS database was queried for visits related to gastroesophageal reflux diagnosis and management. Analysis performed for time periods 1998-2001, 2002-2005, and 2006-2009 was weighted to provide national estimates of care. Results were compared to previously reported time periods from 1990 to 2001 to evaluate patterns in overall visits, age and ethnicity of patients, provider type, and prescriptions provided...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28073285/muscle-nerve-muscle-grafting-for-facial-reanimation-in-rats
#9
Steven J Charous, Jeffery M Hotaling, Bridget D Burgess, Joshua M Sappington, James Park, Grant Turek, Eileen M Foecking
OBJECTIVE: Facial paralysis is a devastating condition leaving patients with a myriad of aesthetic and functional consequences. Muscle-nerve-muscle (MNM) neurotization is a reinnervation technique that involves implanting an autogenous nerve graft as a conduit between an innervated "donor" muscle and a denervated "recipient" muscle. We investigated the use of MNM reinnervation, alone or in combination with electrical stimulation (ES) and testosterone propionate (TP) in comparison to nerve reanastomosis (RE), on functional recovery following rat facial nerve injury...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28073284/posterior-glottic-insufficiency-in-children
#10
Reema Padia, Marshall E Smith
BACKGROUND: Dysphonia secondary to posterior glottic insufficiency (PGI) can be difficult to identify and correct. Inadequate arytenoid approximation from medial arytenoid erosion results in a breathy, soft voice. The anatomical location of the gap is difficult to correct by vocal fold injection laryngoplasty. This study reviews the presentation, evaluation, and treatment for pediatric patients who were identified with PGI. METHODS: An Institutional Review Board-approved chart review was performed on all patients who were diagnosed with PGI at our institution from 2013 to 2015...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28071070/surgery-for-cholesteatomatous-labyrinthine-fistula
#11
John Lim, Anupriya Gangal, Michael Brian Gluth
OBJECTIVE: There is uncertainty regarding the ideal surgical management of cholesteatomatous labyrinthine fistulae. The objective was to review the published evidence to determine whether a difference exists in hearing outcome for cholesteatoma matrix removal or matrix exteriorization. DATA SOURCES: Systematic MEDLINE and Web of Science searches identified publications describing hearing results after cholesteatoma matrix removal or matrix exteriorization. REVIEW METHODS: Three reviewers appraised the studies for quality, level of evidence, and extracted data...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28061634/personalized-medicine-approach-for-an-exceptional-response-to-multiple-recurrent-and-metastatic-her2-positive-oropharyngeal-squamous-cell-carcinoma
#12
Nolan B Seim, Stephen Y Kang, Milan Bhandari, Riley G Jones, Theodoros N Teknos
INTRODUCTION: Advanced stage squamous cell carcinoma of the head and neck carries an overall poor prognosis, and survivorship gains have remained relatively stagnant compared to other malignancies due to its complex tumor biology and lack of proven effective targeting agents. METHODS: We present a case of an exceptional responder to molecular-targeted therapy for metastatic oropharyngeal squamous cell carcinoma using a chemotherapeutic agent FDA approved for breast cancer and targeting the HER2/Neu receptor in order to discuss the larger clinical implications...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28061548/suprafascial-harvest-of-the-radial-forearm-free-flap-decreases-the-risk-of-postoperative-tendon-exposure
#13
David C Shonka, Nikita V Kohli, Benjamin M Milam, Mark J Jameson
OBJECTIVE: To determine if suprafascial harvest of the radial forearm free flap improves postoperative donor site outcomes compared to subfascial harvest. METHODS: Retrospective chart review. RESULTS: Forty-six patients underwent reconstruction of a head and neck defect with a radial forearm free flap (RFFF). Subfascial harvest of the RFFF was performed in 25 (53%) patients and suprafascial harvest performed in 22 (47%) patients. All donor sites were covered with a split thickness skin graft and a bolster that remained in place for 6 days...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/27932524/partial-tonsillectomy-content-and-readability-of-online-health-information
#14
Kevin Wong, Jessica R Levi
OBJECTIVES: Evaluate the content and readability of health information regarding partial tonsillectomy. METHODS: A web search was performed using the term partial tonsillectomy in Google, Yahoo!, and Bing. The first 50 websites from each search were evaluated using HONcode standards for quality and content. Readability was assessed using the Flesch-Kincaid Grade Level (FKGL), Flesch Reading Ease, Gunning-Fog Index, Coleman-Liau Index, Automated Readability Index, and SMOG score...
December 7, 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28056532/analyzing-the-area-under-the-curve-of-pharyngeal-ph-probes-in-the-diagnosis-of-reflux-disease
#15
Joel W Jones, Kevin J Sykes, Anna Pavelonis, Hema Pappu, Amy M Nguyen, James D Garnett
OBJECTIVES: To analyze the area under the curve (AUC) from 24-hour pharyngeal pH probes and evaluate this parameter as a predictor of disease severity for laryngopharyngeal reflux. METHODS: Eighty patients met inclusion criteria of a completed 24-hour pharyngeal pH probe and Reflux Symptom Index (RSI) questionnaire. The AUC was calculated below a pH threshold of 5.5 using the trapezoidal rule. The RSI and RYAN scores were correlated with AUC values, and nonparametric tests were used for comparisons...
December 1, 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28056531/sialendoscopy-for-sublingual-gland-sialolithiasis
#16
Lindsay Goodstein, Lauren Galinat, Joseph Curry, Adam Luginbuhl, David Cognetti
OBJECTIVES: To present a unique series of sublingual gland sialolithiasis treated with sialendoscopy. METHODS: A retrospective chart review of patients at a single tertiary care academic center undergoing sialendoscopy. RESULTS: We present a series of 4 patients who presented with 1 episode each of sialadenitis without preceding postprandial symptoms. In each case, sialendoscopy identified the calculi embedded within the sublingual duct of Bartholin at its emptying point into Wharton's duct...
December 1, 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28056521/evaluating-the-effect-of-spreader-grafting-on-nasal-obstruction-using-the-nose-scale
#17
Aurora G Standlee, Marc H Hohman
OBJECTIVE: The Nasal Obstruction Symptom Evaluation (NOSE) scale has been used to demonstrate that surgery improves nasal obstruction, but no study has directly compared surgical techniques. We performed a retrospective study comparing NOSE scores to quantify the effects of spreader grafting on postoperative nasal patency. METHODS: We compared NOSE scores of patients who underwent septoturbinoplasty to open septorhinoplasty with spreader graft placement. We used a paired samples t test to evaluate the difference between pre- and postoperative NOSE scores and the improvement in NOSE score between patients who underwent septoturbinoplasty and those who underwent open septorhinoplasty with spreader graft placement...
December 1, 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28056518/mucosal-sparing-radiation-therapy-in-resected-oropharyngeal-cancer
#18
Mauricio E Gamez, Michele Y Halyard, Michael L Hinni, Richard E Hayden, Thomas H Nagel, Carlos E Vargas, William W Wong, Kelly K Curtis, Matthew A Zarka, Daniel Ma, Samir H Patel
PURPOSE: To report the outcomes of patients with favorable risk oropharyngeal cancer that underwent adjuvant radiation therapy with omission of the primary site from the clinical target volume (CTV). MATERIAL/METHODS: A retrospective study of 40 patients treated with transoral surgery (TOS) followed by neck only radiation using intensity modulated radiation therapy (IMRT) with exclusion of the primary site. For all patients, a CTV of the primary surgical bed was contoured to obtain the estimated incidental dose to the primary site...
December 1, 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28056517/ewing-sarcoma-of-the-head-and-neck
#19
Mark A Ellis, Daniel R Gerry, David M Neskey, Eric J Lentsch
OBJECTIVES: Ewing sarcoma is a rare tumor of the head and neck. Previous efforts to characterize Ewing sarcoma of the head and neck (ES-HN) have been limited to small retrospective series. The objective of this study was to analyze the demographic, clinicopathologic, treatment, and survival characteristics of ES-HN compared to Ewing sarcoma at other locations (ES-other). METHODS: Using the Surveillance, Epidemiology, and End Results (SEER) database, we compared 183 patients with ES-HN to 3177 patients with ES-other...
December 1, 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28006951/influence-of-external-subglottic-air-flow-on-dysphagic-tracheotomized-patients-with-severe-brain-injury
#20
Mohit Kothari, Katje Bjerrum, Lars Hedemann Nielsen, Jim Jensen, Jørgen Feldbæk Nielsen
OBJECTIVE: The aim of this study was to determine if external subglottic air flow (ESAF) influences swallowing frequency in severely dysphagic tracheotomized patients with brain injury. METHODS: Ten patients were recruited at the neurological intensive care unit. The ESAF intervention was provided through the standard cuffed suction aid tracheotomy tube, which primarily is used to suction residual secretion volume from the subglottic area. Sessions were 150 minutes, and ESAF was provided at 60-65, 90-95, and 120-125 minutes at 3 L/min...
December 1, 2016: Annals of Otology, Rhinology, and Laryngology
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