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Annals of Nuclear Medicine

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https://www.readbyqxmd.com/read/30014440/a-systematic-review-of-the-prognostic-value-of-texture-analysis-in-18-f-fdg-pet-in-lung-cancer
#1
Sangwon Han, Sungmin Woo, Chong Hyun Suh, Yeon Joo Kim, Jungsu S Oh, Jong Jin Lee
OBJECTIVE: The aim of this study was to perform a systematic review of the prognostic value of texture parameters derived by 18 F-fluorodeoxyglucose positron emission tomography (18 F-FDG PET) in patients with lung cancer. METHODS: PubMed and EMBASE databases were searched up to March 12, 2018, for original articles involving texture analysis for the prediction of prognosis in patients with lung cancer. Risk of bias in the studies was critically assessed using the QUIPS tool...
July 16, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/30014439/detectability-of-residual-invasive-bladder-cancer-in-delayed-18-f-fdg-pet-imaging-with-oral-hydration-using-500-ml-of-water-and-voiding-refilling
#2
Akira Higashiyama, Tsuyoshi Komori, Hiroshi Juri, Yuki Inada, Haruhito Azuma, Yoshifumi Narumi
OBJECTIVE: 2-Fluorine-18-fluoro-2-deoxy-D-glucose positron emission tomography (18 F-FDG PET) imaging is not considered useful for assessing bladder cancer due to the physiological uptake of 18 F-FDG in the bladder. Despite reports of the detection of bladder cancer by washing out 18 F-FDG from the bladder, such methods are invasive and impractical in the routine practice. The purpose of this study was to evaluate prospectively the utility of oral hydration with 500 mL of water and voiding-refilling, a minimally invasive method that we introduced to enable detection of residual invasive bladder cancer on delayed 18 F-FDG PET imaging...
July 16, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/30006752/prognostic-value-of-68-ga-psma-i-t-pet-ct-suv-parameters-on-survival-outcome-in-advanced-prostat-cancer
#3
Halil Komek, Canan Can, Ugur Yilmaz, Serdar Altindag
OBJECTIVE: To determine the association of 68 Ga-PSMA-I&T PET/CT SUV parameters with survival outcome in advanced prostate cancer patients. METHODS: A total of 148 consecutive patients mean age: 69.3 ± 7.8 years with advanced prostate cancer who underwent 68 Ga-PSMA-I&T PET/CT were included in this retrospective study. Data on previous treatments, serum PSA levels (ng/mL), 68 Ga-PSMA-I&T PET/CT findings metastases as well as survival data were recorded...
July 13, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29982990/prognostic-role-of-pretreatment-18f-fdg-pet-ct-in-primary-brain-lymphoma
#4
Domenico Albano, Mattia Bertoli, Marco Battistotti, Carlo Rodella, Massimo Statuto, Raffaele Giubbini, Francesco Bertagna
OBJECTIVE: Primary brain lymphoma is an aggressive extranodal non-Hodgkin lymphoma with poor prognosis. Many possible prognostic factors are investigated with controversial results, but possible prognostic role of 18fluorine-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) features remains unclear. Our aim was to study the metabolic behavior of brain lymphoma at 18F-FDG PET/CT and the prognostic impact of qualitative and semiquantitative PET/CT parameters...
July 7, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29982989/reproducibility-of-standardized-uptake-values-of-same-day-randomized-68-ga-psma-11-pet-ct-and-pet-mr-scans-in-recurrent-prostate-cancer-patients
#5
Anna Ringheim, Guilherme de Carvalho Campos Neto, Karine Minaif Martins, Taise Vitor, Marcelo Livorsi da Cunha, Ronaldo Hueb Baroni
OBJECTIVE: Positron emission tomography in association with magnetic resonance imaging (PET/MR) and 68 Ga-PSMA-11 has shown superior detection in recurrent prostate cancer patients as compared to PET/computed tomography (PET/CT). There are, however, several technological differences between PET/CT and PET/MR systems which affect the PET image quality. The objective of this study was to assess the reproducibility of PET/CT and PET/MR SUV's in recurrent prostate cancer patients. We randomized the patients regarding the order of the PET/CT and PET/MR scans to reduce the influence of tracer uptake as a function of time...
July 7, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29974372/is-18-f-fdg-pet-ct-useful-for-the-differential-diagnosis-of-solitary-pulmonary-nodules-in-patients-with-idiopathic-pulmonary-fibrosis
#6
Suk Hyun Lee, Changhwan Sung, Hyo Sang Lee, Hee-Young Yoon, Soo-Jong Kim, Jungsu S Oh, Jin Woo Song, Mi Young Kim, Jin-Sook Ryu
OBJECTIVE: Idiopathic pulmonary fibrosis (IPF) is associated with an increased incidence of lung cancer, but patients with IPF often have poor pulmonary function and are vulnerable to pneumothorax and so using an invasive procedure to diagnose a single nodule detected on chest CT risks a critical adverse outcome. 18 F-fluorodeoxyglucose (18 F-FDG) positron emission tomography/computed tomography (PET/CT) is recognized to be useful for differentiating between benign and malignant solitary pulmonary nodules (SPN) in patients without IPF, but its diagnostic accuracy has not been investigated in patients with IPF...
July 4, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29934675/evaluation-of-the-default-mode-network-by-quantitative-15-o-pet-comparative-study-between-cerebral-blood-flow-and-oxygen-consumption
#7
Jo Aoe, Tadashi Watabe, Eku Shimosegawa, Hiroki Kato, Yasukazu Kanai, Sadahiro Naka, Keiko Matsunaga, Kayako Isohashi, Mitsuaki Tatsumi, Jun Hatazawa
OBJECTIVE: Resting-state functional MRI (rs-fMRI) has revealed the existence of a default-mode network (DMN) based on spontaneous oscillations of the blood oxygenation level-dependent (BOLD) signal. The BOLD signal reflects the deoxyhemoglobin concentration, which depends on the relationship between the regional cerebral blood flow (CBF) and the cerebral metabolic rate of oxygen (CMRO2 ). However, these two factors cannot be separated in BOLD rs-fMRI. In this study, we attempted to estimate the functional correlations in the DMN by means of quantitative 15 O-labeled gases and water PET, and to compare the contribution of the CBF and CMRO2 to the DMN...
June 22, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29931622/reconstruction-segmentation-of-attenuation-map-in-tof-pet-based-on-mixture-models
#8
Hamidreza Hemmati, Alireza Kamali-Asl, Pardis Ghafarian, Mohammad Reza Ay
Attenuation correction is known as a necessary step in positron emission tomography (PET) system to have accurate and quantitative activity images. Emission-based method is known as a promising approach for attenuation map estimation on TOF-PET scanners. The proposed method in this study imposes additional histogram-based information as a mixture model prior on the emission-based approach using maximum a posteriori (MAP) framework to improve its performance and make such a nearly segmented attenuation map. To eliminate misclassification of histogram modeling, a Median root prior is incorporated on the proposed approach to reduce the noise between neighbor voxels and encourage spatial smoothness in the reconstructed attenuation map...
June 21, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29926343/publisher-correction-to-18-f-fdg-pet-ct-metabolic-tumor-parameters-and-radiomics-features-in-aggressive-non-hodgkin-s-lymphoma-as-predictors-of-treatment-outcome-and-survival
#9
Aatif Parvez, Noam Tau, Douglas Hussey, Manjula Maganti, Ur Metser
In the original publication of the article, the title was incorrectly.
June 20, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29926342/clinical-application-of-99m-tc-hynic-toc-spect-ct-in-diagnosing-and-monitoring-of-pancreatic-neuroendocrine-neoplasms
#10
Junyan Xu, Yi Li, Xiaoping Xu, Jiangang Zhang, Yingjian Zhang, Xianjun Yu, Dan Huang
OBJECTIVE: Our aim of this research was to determine the value of SPECT/CT with 99m Tc-HYNIC-TOC for evaluation of the pancreatic masses which were suspected as neuroendocrine neoplasms and follow-up of patients with pancreatic neuroendocrine neoplasms. METHODS: We retrospectively analyzed 184 patients who performed 99m Tc-HYNIC-TOC SPECT/CT. All the patients were divided into two groups: one for assessment of diagnostic efficiency for pancreatic suspected masses (n = 140) and another for monitoring recurrence after surgery (n = 44)...
June 20, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29948622/diagnosing-polymyalgia-rheumatica-on-18-f-fdg-pet-ct-typical-uptake-patterns
#11
Shunsuke Yuge, Koya Nakatani, Kumiko Yoshino, Takashi Koyama
OBJECTIVE: The diagnosis of polymyalgia rheumatica (PMR) is often challenging, since similar clinical features and laboratory findings can be observed in several inflammatory conditions. PMR involves affected sites in a specific manner, and 18 F-FDG PET/CT has the advantage for assessing the disease activity of each site. The purpose of this study was to identify the patterns of 18 F-FDG uptake that suggest the diagnosis of PMR. METHODS: We studied 60 patients who had undergone 18 F-FDG PET/CT scans for workup of suspected PMR, arthritis, enthesitis, or myopathy...
June 8, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29869193/reliable-radiosynthesis-of-4-10-b-borono-2-18-f-fluoro-l-phenylalanine-with-quality-assurance-for-boron-neutron-capture-therapy-oriented-diagnosis
#12
Kiichi Ishiwata, Ryoichi Ebinuma, Chuichi Watanabe, Kunpei Hayashi, Jun Toyohara
OBJECTIVE: The aim of this study was to establish a reliable and routine method for the preparation of 4-[10 B]borono-2-[18 F]fluoro-L-phenylalanine (L-[18 F]FBPA) for boron neutron capture therapy-oriented diagnosis using positron emission tomography. METHODS: To produce L-[18 F]FBPA by electrophilic fluorination of 4-[10 B]borono-L-phenylalanine (L-BPA) with [18 F]acetylhypofluorite ([18 F]AcOF) via [18 F]F2 derived from the 20 Ne(d,α)18 F nuclear reaction, several preparation parameters and characteristics of L-[18 F]FBPA were investigated, including: pre-irradiation for [18 F]F2 production, the carrier F2 content in the Ne target, L-BPA-to-F2 ratios, separation with high-performance liquid chromatography (HPLC) using 10 different eluents, enantiomeric purity, and residual trifluoroacetic acid used as the reaction solvent by gas chromatography-mass spectrometry...
June 5, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29858797/assessment-of-tumor-response-to-chemoradiotherapy-and-predicting-prognosis-in-patients-with-head-and-neck-squamous-cell-carcinoma-by-percist
#13
Takayuki Katsuura, Kazuhiro Kitajima, Masayuki Fujiwara, Tomonori Terada, Nobuhiro Uwa, Kazuma Noguchi, Hiroshi Doi, Yukihisa Tamaki, Rika Yoshida, Tatsuya Tsuchitani, Masahiro Fujita, Koichiro Yamakado
PURPOSE: To evaluate therapeutic response to chemoradiotherapy and prediction of recurrence and death in patients with head and neck squamous cell carcinoma (HNSCC) using Positron Emission Tomography Response Criteria in Solid Tumors (PERCIST). MATERIALS AND METHODS: Forty-two patients (mean 63.4, range 20-79 years) with nasopharyngeal (n = 10), oropharyngeal (n = 13), hypopharyngeal (n = 11), or laryngeal (n = 8) cancer underwent fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) before and approximately 3 months (mean 95...
June 1, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29797003/radiation-exposure-after-177-lu-dotatate-and-177-lu-psma-617-therapy
#14
Christian Mair, Boris Warwitz, Katharina Fink, Lorenza Scarpa, Bernhard Nilica, Johanna Maffey-Steffan, Sabine Buxbaum, Irene J Virgolini
PURPOSE: As radionuclide therapy is gaining importance in palliative treatment of patients suffering from neuroendocrine tumour (NET) as well as castration resistant prostate cancer (CRPC), the radiation protection of patients, staff, family members and the general public is of increasing interest. Here, we determine patient discharge dates according to European guidelines. METHODS: In 40 patients with NET and 25 patients with CRPC organ and tumour doses based on the MIRD concept were calculated from data obtained during the first therapy cycle...
May 23, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29797001/optimal-monochromatic-color-combinations-for-fusion-imaging-of-fdg-pet-and-diffusion-weighted-mr-images
#15
Ryotaro Kamei, Yuji Watanabe, Koji Sagiyama, Takuro Isoda, Osamu Togao, Hiroshi Honda
OBJECTIVE: To investigate the optimal monochromatic color combination for fusion imaging of FDG-PET and diffusion-weighted MR images (DW) regarding lesion conspicuity of each image. METHODS: Six linear monochromatic color-maps of red, blue, green, cyan, magenta, and yellow were assigned to each of the FDG-PET and DW images. Total perceptual color differences of the lesions were calculated based on the lightness and chromaticity measured with the photometer. Visual lesion conspicuity was also compared among the PET-only, DW-only and PET-DW-double positive portions with mean conspicuity scores...
May 23, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29774458/effects-of-rs591323-on-serotonin-transporter-availability-in-healthy-male-subjects
#16
Kyoungjune Pak, Hyun-Yeol Nam, Seunghyeon Shin, Keunyoung Kim, Myung Jun Lee, Eun-Joo Kim, Jae Meen Lee, Seong-Jang Kim, In Joo Kim
OBJECTIVES: We aimed to investigate the association between genetic factors of SNPs dopamine transporter (DAT) and serotonin transporter (SERT) availabilities in healthy controls. METHODS: The study population consisted of healthy controls with screening 123 I-FP-CIT single-photon emission computed tomography. Specific binding of 123 I-FP-CIT regarding DAT and SERT was calculated using a region of interest analysis. VOI template was applied to measure specific binding ratios (SBRs) of caudate nucleus, putamen, striatum, midbrain, and pons...
May 17, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29766463/predictive-factors-for-the-outcomes-of-initial-i-131-low-dose-ablation-therapy-to-japanese-patients-with-differentiated-thyroid-cancer
#17
Shinji Ito, Shingo Iwano, Katsuhiko Kato, Shinji Naganawa
OBJECTIVE: To identify prognostic factors associated with a low-iodine diet (LID) and the amount of remnant thyroid tissue in Japanese patients with differentiated thyroid cancer (DTC) who received initial I-131 remnant ablation (RAI) using a fixed low dose of I-131 (1110 MBq). PATIENTS AND METHODS: In this prospective study, we enrolled 45 patients. Patients were classified into a self-managed LID group and a strict LID group. We measured the urinary iodine concentration on the day of RAI after patients consumed LID for 2 weeks...
May 15, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29754276/-718-f-fdg-pet-ct-metabolic-tumor-parameters-and-radiomics-features-in-aggressive-non-hodgkin-s-lymphoma-as-predictors-of-treatment-outcome-and-survival
#18
Aatif Parvez, Noam Tau, Douglas Hussey, Manjula Maganti, Ur Metser
PURPOSE: To determine whether metabolic tumor parameters and radiomic features extracted from 18 F-FDG PET/CT (PET) can predict response to therapy and outcome in patients with aggressive B-cell lymphoma. METHODS: This institutional ethics board-approved retrospective study included 82 patients undergoing PET for aggressive B-cell lymphoma staging. Whole-body metabolic tumor volume (MTV) using various thresholds and tumor radiomic features were assessed on representative tumor sites...
May 12, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29730823/the-correlation-between-striatal-and-cortical-binding-ratio-of-11-c-pib-pet-in-amyloid-uptake-positive-patients
#19
Julia Sauerbeck, Kazunari Ishii, Chisa Hosokawa, Hayato Kaida, Franziska T Scheiwein, Kohei Hanaoka, Axel Rominger, Matthias Brendel, Peter Bartenstein, Takamichi Murakami
PURPOSE: In subjects with amyloid deposition, striatal accumulation of 11 C-Pittsburgh compound B (PiB) demonstrated by positron emission tomography (PET) is related to the stage of Alzheimer's disease (AD). In this study, we investigated the correlation between striatal and cortical non-displaceable binding potential (BPND ). METHODS: Seventy-three subjects who complained of cognitive disturbance underwent dynamic PiB-PET studies and showed positive PiB accumulation were retrospectively selected...
May 5, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29713999/implications-of-electrocardiographic-frontal-qrs-axis-on-left-ventricular-diastolic-parameters-derived-from-electrocardiogram-gated-myocardial-perfusion-single-photon-emission-computed-tomography
#20
Satoshi Kurisu, Kazuhiro Nitta, Yoji Sumimoto, Hiroki Ikenaga, Ken Ishibashi, Yukihiro Fukuda, Yasuki Kihara
BACKGROUND: Current electrocardiographic (ECG) machines report various variables including frontal QRS axis automatically. We tested the hypothesis that QRS axis is associated with left ventricular (LV) diastolic parameters derived from ECG-gated myocardial perfusion single photon emission computed tomography (SPECT) independent of myocardial ischemia. METHODS: Ninety-three patients with preserved LV ejection fraction and no evidence of myocardial ischemia were enrolled based on ECG-gated SPECT...
April 30, 2018: Annals of Nuclear Medicine
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