Alaa Abd-Elsayed, Cain W Stark, Natasha Topoluk, Mir Isaamullah, Paul Uzodinma, Omar Viswanath, Michael J Gyorfi, Osama Fattouh, Kevin C Schlidt, Omar Dyara
Complex regional pain syndrome (CRPS) is a debilitating chronic pain condition that, although exceedingly rare, carries a significant burden for the affected patient population. The complex and ambiguous pathophysiology of this condition further complicates clinical management and therapeutic interventions. Furthermore, being a diagnosis of exclusion requires a diligent workup to ensure an accurate diagnosis and subsequent targeted management. The development of the Budapest diagnostic criteria helped to consolidate existing definitions of CRPS but extensive work remains in identifying the underlying pathways...
December 2024: Annals of Medicine