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Annals of Internal Medicine

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https://www.readbyqxmd.com/read/28715848/patient-outcomes-in-dose-reduction-or-discontinuation-of-long-term-opioid-therapy-a-systematic-review
#1
Joseph W Frank, Travis I Lovejoy, William C Becker, Benjamin J Morasco, Christopher J Koenig, Lilian Hoffecker, Hannah R Dischinger, Steven K Dobscha, Erin E Krebs
Background: Expert guidelines recommend reducing or discontinuing long-term opioid therapy (LTOT) when risks outweigh benefits, but evidence on the effect of dose reduction on patient outcomes has not been systematically reviewed. Purpose: To synthesize studies of the effectiveness of strategies to reduce or discontinue LTOT and patient outcomes after dose reduction among adults prescribed LTOT for chronic pain. Data Sources: MEDLINE, EMBASE, PsycINFO, CINAHL, and the Cochrane Library from inception through April 2017; reference lists; and expert contacts...
July 18, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28715843/the-pharmaceuticalization-of-the-tobacco-industry
#2
Yogi Hale Hendlin, Jesse Elias, Pamela M Ling
No abstract text is available yet for this article.
July 18, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28715842/changing-the-conversation-about-opioid-tapering
#3
Deborah Dowell, Tamara M Haegerich
No abstract text is available yet for this article.
July 18, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28693043/sensitivity-analysis-in-observational-research-introducing-the-e-value
#4
Tyler J VanderWeele, Peng Ding
Sensitivity analysis is useful in assessing how robust an association is to potential unmeasured or uncontrolled confounding. This article introduces a new measure called the "E-value," which is related to the evidence for causality in observational studies that are potentially subject to confounding. The E-value is defined as the minimum strength of association, on the risk ratio scale, that an unmeasured confounder would need to have with both the treatment and the outcome to fully explain away a specific treatment-outcome association, conditional on the measured covariates...
July 11, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28693041/rethinking-how-to-measure-the-appropriateness-of-cervical-cancer-screening
#5
Natasha K Parekh, Julie M Donohue, Aiju Men, Jennifer Corbelli, Marian Jarlenski
No abstract text is available yet for this article.
July 11, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28693040/is-coffee-consumption-associated-with-lower-risk-for-death
#6
(no author information available yet)
No abstract text is available yet for this article.
July 11, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28693039/moderate-coffee-intake-can-be-part-of-a-healthy-diet
#7
Eliseo Guallar, Elena Blasco-Colmenares, Dan E Arking, Di Zhao
No abstract text is available yet for this article.
July 11, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28693038/coffee-drinking-and-mortality-in-10-european-countries-a-multinational-cohort-study
#8
Marc J Gunter, Neil Murphy, Amanda J Cross, Laure Dossus, Laureen Dartois, Guy Fagherazzi, Rudolf Kaaks, Tilman Kühn, Heiner Boeing, Krasimira Aleksandrova, Anne Tjønneland, Anja Olsen, Kim Overvad, Sofus Christian Larsen, Maria Luisa Redondo Cornejo, Antonio Agudo, María José Sánchez Pérez, Jone M Altzibar, Carmen Navarro, Eva Ardanaz, Kay-Tee Khaw, Adam Butterworth, Kathryn E Bradbury, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Domenico Palli, Sara Grioni, Paolo Vineis, Salvatore Panico, Rosario Tumino, Bas Bueno-de-Mesquita, Peter Siersema, Max Leenders, Joline W J Beulens, Cuno U Uiterwaal, Peter Wallström, Lena Maria Nilsson, Rikard Landberg, Elisabete Weiderpass, Guri Skeie, Tonje Braaten, Paul Brennan, Idlir Licaj, David C Muller, Rashmi Sinha, Nick Wareham, Elio Riboli
Background: The relationship between coffee consumption and mortality in diverse European populations with variable coffee preparation methods is unclear. Objective: To examine whether coffee consumption is associated with all-cause and cause-specific mortality. Design: Prospective cohort study. Setting: 10 European countries. Participants: 521 330 persons enrolled in EPIC (European Prospective Investigation into Cancer and Nutrition)...
July 11, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28693037/sensitivity-analysis-for-unmeasured-confounding-e-values-for-observational-studies
#9
A Russell Localio, Catherine B Stack, Michael E Griswold
No abstract text is available yet for this article.
July 11, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28693036/association-of-coffee-consumption-with-total-and-cause-specific-mortality-among-nonwhite-populations
#10
Song-Yi Park, Neal D Freedman, Christopher A Haiman, Loïc Le Marchand, Lynne R Wilkens, Veronica Wendy Setiawan
Background: Coffee consumption has been associated with reduced risk for death in prospective cohort studies; however, data in nonwhites are sparse. Objective: To examine the association of coffee consumption with risk for total and cause-specific death. Design: The MEC (Multiethnic Cohort), a prospective population-based cohort study established between 1993 and 1996. Setting: Hawaii and Los Angeles, California. Participants: 185 855 African Americans, Native Hawaiians, Japanese Americans, Latinos, and whites aged 45 to 75 years at recruitment...
July 11, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28672343/the-association-of-firearm-suicide-with-mental-illness-substance-use-conditions-and-previous-suicide-attempts
#11
Jennifer M Boggs, Gregory E Simon, Brian K Ahmedani, Edward Peterson, Samuel Hubley, Arne Beck
No abstract text is available yet for this article.
July 4, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28672324/high-generic-drug-prices-and-market-competition-a-retrospective-cohort-study
#12
Chintan V Dave, Aaron S Kesselheim, Erin R Fox, Peihua Qiu, Abraham Hartzema
Background: Prices for some generic drugs have increased in recent years, adversely affecting patients who rely on them. Objective: To determine the association between market competition levels and the change in generic drug prices in the United States. Design: Retrospective cohort study. Setting: Prescription claims from commercial health plans between 2008 and 2013. Measurements: The 5.5 years of data were divided into 11 study periods of 6 months each...
July 4, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28672286/fool-me-thrice-the-evolving-story-of-multiply-recurrent-clostridium-difficile-infection
#13
Sameer D Saini, Akbar K Waljee
No abstract text is available yet for this article.
July 4, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28672282/increasing-incidence-of-multiply-recurrent-clostridium-difficile-infection-in-the-united-states-a-cohort-study
#14
Gene K Ma, Colleen M Brensinger, Qufei Wu, James D Lewis
Background: Clostridium difficile infection (CDI), the most common health care-associated infection, often recurs. Fecal microbiota transplantation is increasingly used to treat multiply recurrent CDI (mrCDI). Objective: To determine whether the incidence of mrCDI is increasing in proportion to CDI and to identify risk factors for mrCDI. Design: Retrospective cohort study. Setting: United States. Participants: 38 911 718 commercially insured patients in the OptumInsight Clinformatics Database, of whom 45 341 developed CDI...
July 4, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28655034/the-relationship-of-health-insurance-and-mortality-is-lack-of-insurance-deadly
#15
Steffie Woolhandler, David U Himmelstein
About 28 million Americans are currently uninsured, and millions more could lose coverage under policy reforms proposed in Congress. At the same time, a growing number of policy leaders have called for going beyond the Affordable Care Act to a single-payer national health insurance system that would cover every American. These policy debates lend particular salience to studies evaluating the health effects of insurance coverage. In 2002, an Institute of Medicine review concluded that lack of insurance increases mortality, but several relevant studies have appeared since that time...
June 27, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28654980/consort-extension-for-chinese-herbal-medicine-formulas-2017-recommendations-explanation-and-elaboration
#16
Chung-Wah Cheng, Tai-Xiang Wu, Hong-Cai Shang, You-Ping Li, Douglas G Altman, David Moher, Zhao-Xiang Bian
Chinese herbal medicine (CHM) formulas are the major components of traditional Chinese medicine (TCM) interventions. The general reporting quality of randomized controlled trials (RCTs) of CHM formulas is disappointing, although CONSORT (Consolidated Standards of Reporting Trials) Statement extensions for herbal medicinal interventions and acupuncture interventions are available. A group of TCM clinical experts, methodologists, epidemiologists, and editors has developed this CONSORT Extension for CHM Formulas (CONSORT-CHM Formulas 2017) through a comprehensive process, including publication of the draft version, solicitation of comments, revision, and finalization...
June 27, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28654973/erosive-rheumatoid-arthritis-after-bilateral-hand-transplantation
#17
Brittany L Adler, Jemima Albayda, Jamie T Shores, W P Andrew Lee, Gerald Brandacher, Clifton O Bingham
No abstract text is available yet for this article.
June 27, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28654971/incorporating-whole-genome-sequencing-into-primary-care-falling-barriers-and-next-steps
#18
Teri A Manolio
No abstract text is available yet for this article.
June 27, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28654966/randomized-trials-of-chinese-herbal-medicine-a-new-extension-of-the-consort-statement
#19
Klaus Linde, Benno Brinkhaus
No abstract text is available yet for this article.
June 27, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28654958/the-impact-of-whole-genome-sequencing-on-the-primary-care-and-outcomes-of-healthy-adult-patients-a-pilot-randomized-trial
#20
Jason L Vassy, Kurt D Christensen, Erica F Schonman, Carrie L Blout, Jill O Robinson, Joel B Krier, Pamela M Diamond, Matthew Lebo, Kalotina Machini, Danielle R Azzariti, Dmitry Dukhovny, David W Bates, Calum A MacRae, Michael F Murray, Heidi L Rehm, Amy L McGuire, Robert C Green
Background: Whole-genome sequencing (WGS) in asymptomatic adults might prevent disease but increase health care use without clinical value. Objective: To describe the effect on clinical care and outcomes of adding WGS to standardized family history assessment in primary care. Design: Pilot randomized trial. (ClinicalTrials.gov: NCT01736566). Setting: Academic primary care practices. Participants: 9 primary care physicians (PCPs) and 100 generally healthy patients recruited at ages 40 to 65 years...
June 27, 2017: Annals of Internal Medicine
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