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Annals of Allergy, Asthma & Immunology

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https://www.readbyqxmd.com/read/29660515/aspergillus-fumigatus-viability-drives-allergic-responses-to-inhaled-conidia
#1
Ajay P Nayak, Tara L Croston, Angela R Lemons, W T Goldsmith, Nikki B Marshall, Michael L Kashon, Dori R Germolec, Donald H Beezhold, Brett J Green
BACKGROUND: Aspergillus fumigatus induced allergic airway disease has been shown to involve conidial germination in vivo but the immunological mechanisms remain uncharacterized. OBJECTIVE: A subchronic murine exposure model was used to examine the immunological mediators that are regulated in response to either culturable or non-culturable A. fumigatus conidia. METHODS: Female B6C3F1/N mice were repeatedly dosed via inhalation with 1 x 105 viable or heat inactivated conidia (HIC), twice a week for 13 weeks (26 exposures)...
April 13, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29656145/sq-house-dust-mite-sublingual-immunotherapy-tablet-subgroup-efficacy-and-local-application-site-reaction-duration
#2
David I Bernstein, Joerg Kleine-Tebbe, Harold S Nelson, Jose A Bardelas, Gordon L Sussman, Susan Lu, Dorte Rehm, Bodil Svanholm Fogh, Hendrik Nolte
BACKGROUND: Allergic rhinitis with or without conjunctivitis (AR/C) is common, necessitating evaluation of SQ house dust mite (HDM) sublingual immunotherapy (SLIT)-tablet efficacy in various subgroups. OBJECTIVE: To evaluate 12 SQ-HDM efficacy and safety across subgroups, and the onset, duration, and recurrence of local application site reactions. METHODS: Subgroup (age, gender, race, asthma status, and allergen sensitization) efficacy was assessed using pooled data from two previously described trials of daily 12 SQ-HDM vs placebo for AR/C (N=2138)...
April 12, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29656144/short-and-long-term-management-of-cases-of-venom-induced-anaphylaxis-via-is-suboptimal
#3
Ashley Tritt, Sofianne Gabrielli, Sarah Zahabi, Ann Clarke, Jocelyn Moisan, Harley Eisman, Judy Morris, Lea Restivo, Greg Shand, Moshe Ben-Shoshan
BACKGROUND: Venom induced anaphylaxis (VIA) accounts for severe reactions. However, little is known about the short and long-term management of VIA cases. OBJECTIVE: To assess the short and long-term management of VIA. METHODS: Using a national anaphylaxis registry (C-CARE), we identified VIA cases presenting to EDs in Montreal and to emergency medical services(EMS) in Western Quebec over a four-year period. Data were collected on clinical characteristics, triggers, and management...
April 12, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29653238/the-pediatric-asthma-yardstick-practical-recommendations-for-a-sustained-step-up-in-asthma-therapy-for-children-with-inadequately-controlled-asthma
#4
Bradley E Chipps, Leonard B Bacharier, Judith R Farrar, Daniel J Jackson, Kevin R Murphy, Wanda Phipatanakul, Stanley J Szefler, W Gerald Teague, Robert S Zeiger
Current asthma guidelines recommend a control-based approach to management involving assessment of impairment and risk followed by implementation of treatment strategies individualized according to the patient's needs and preferences. However, for children with asthma, achieving control can be elusive. While tools are available to help children (and families) track and manage day-to-day symptoms, when and how to implement a longer-term step-up in care is less clear. Furthermore, treatment is challenged by the three age groups of childhood - adolescence (12-18 years old), school age (6-11 years old), and young children (≤ 5 years old), and what works for one age group may not be the best approach for another...
April 10, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29653237/oral-corticosteroids-should-be-available-on-hand-at-home-for-the-next-asthma-exacerbation
#5
Miles Weinberger, Leslie Hendeles, Mutasim Abu-Hasan
No abstract text is available yet for this article.
April 10, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29653236/chromosome-1q23-3q31-1-deletion-associated-with-decreased-newborn-screening-of-t-cell-receptor-rearrangement-circles-trecs
#6
Julia S Lee, Bradley A Becker, Amelia Kirby, Alan P Knutsen
No abstract text is available yet for this article.
April 10, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29653235/factors-correlated-with-repeated-aspirin-dosing-during-aspirin-desensitization
#7
Charles F Schuler, James L Baldwin, Alan P Baptist
BACKGROUND: Aspirin desensitization is an appropriate procedure for many patients with aspirin-exacerbated respiratory disease (AERD). Patients can require aspirin re-dosing, which prolongs the desensitization process. The frequency of this is not widely reported, nor is it known which patients will require multiple re-dosing. OBJECTIVE: To determine the frequency of and factors associated with repeat aspirin re-dosing during desensitization. METHODS: Charts of aspirin desensitization procedures from 2011-2016 at the University of Michigan Allergy/Immunology Clinic were reviewed...
April 10, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29653234/mepolizumab-use-post-approval-academic-practice-experience
#8
Mariel R Benjamin, Bruce S Bochner, Anju T Peters
No abstract text is available yet for this article.
April 10, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29630929/urban-versus-rural-residency-and-allergy-prevalence-among-adult-women-iowa-women-s-health-study
#9
Niharika P Patel, Anna E Prizment, Bharat Thyagarajan, Evan Roberts, Heather H Nelson, Timothy R Church, DeAnn Lazovich
BACKGROUND: The association between residence and allergy has been well studied in children living on a farm; however, studies of this association in late adulthood are lacking. OBJECTIVE: This study examined the association between residence and allergy in 25,393 women aged 55-69 years in the large prospective Iowa Women's Health Study (IWHS). METHODS: IWHS questionnaires collected information on socio-demographic and anthropometric characteristics, medical history, lifestyle behaviors, dietary intake, residence and allergy...
April 6, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29626629/the-burden-of-allergic-rhinitis-and-allergic-rhinoconjunctivitis-on-adolescents-a-literature-review
#10
REVIEW
Michael S Blaiss, Eva Hammerby, Susan Robinson, Tessa Kennedy-Martin, Sarah Buchs
OBJECTIVE: To evaluate the literature regarding the burden of allergic rhinitis (AR) and allergic rhinoconjunctivitis (ARC) in adolescents (10-19 years). DATA SOURCES: Searches were performed in MEDLINE, Embase, Health Technology Assessment Database, and National Health Service Economic Evaluation Database for studies evaluating concepts of symptoms, quality of life (QOL), daily activities, sleep, examination performance, school absenteeism and presenteeism, and treatment burden in adolescents with AR or ARC...
April 4, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29604336/mast-cell-disorders-protean-manifestations-and-treatment-responses
#11
Meng Chen, Alexander Kim, Bruce Zuraw, Taylor A Doherty, Sandra Christiansen
No abstract text is available yet for this article.
March 28, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29580846/barriers-to-medication-adherence-in-asthma-the-importance-of-culture-and-context
#12
REVIEW
Elizabeth L McQuaid
OBJECTIVE: Significant disparities exist in asthma outcomes. Racial and ethnic minorities have lower controller medication adherence, which may contribute to differences in asthma morbidity between minority and non-minority groups. The objective of this review is to identify individual, patient-provider communication, and systems issues that contribute to this pattern of medication underuse and to discuss potential strategies for intervention. DATA SOURCES: Data were gathered from numerous sources, including reports of pharmacy and medical records, observational studies, and trials...
March 23, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29580845/occupational-exposure-and-asthma
#13
REVIEW
Anh Dao, David I Bernstein
No abstract text is available yet for this article.
March 23, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29577980/safety-of-a-two-day-ultra-rush-immunotherapy-in-vespid-allergic-patients-focus-on-elevated-serum-tryptase
#14
Maria Beatrice Bilò, Alice Corsi, Stefano Agolini, Chiara Tontini, Leonardo Antonicelli
No abstract text is available yet for this article.
March 22, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29577979/from-the-pages-of-allergywatch-recent-advances-in-our-understanding-of-the-environment-s-role-in-allergy
#15
Chitra Dinakar, Stanley M Fineman, Bradley E Chipps, David A Khan, Stephen A Tilles
No abstract text is available yet for this article.
March 22, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29573961/impact-of-dosage-timing-of-once-daily-inhaled-corticosteroids-in-asthma-a-systematic-review-and-meta-analysis
#16
Jae-Uk Song, Hye Kyeong Park, Jonghoo Lee
BACKGROUND: Once-daily inhaled corticosteroids (ICSs) are widely used as first-line therapy in patients with asthma. OBJECTIVE: To compare the efficacy of ICSs administered once daily in the morning or evening as determined by lung function. METHODS: Medline, Embase, and the Cochrane Central Register were searched for relevant clinical trials. The primary outcome was lung function assessed as trough forced expiratory volume in 1 second and peak expiratory flow at end point...
March 21, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29573960/does-the-asthma-visual-analog-scale-relate-to-the-asthma-control-questionnaire
#17
Sunny Jabbal, Brian J Lipworth
No abstract text is available yet for this article.
March 21, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29573959/severe-life-threatening-asthma-precipitated-by-a-topical-nonsteroidal-anti-inflammatory-drug
#18
Nathanael Z E Foong, Anthony C A Yii, Anne A L Hsu
No abstract text is available yet for this article.
March 21, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29567359/validity-and-responsiveness-of-the-urticaria-activity-and-impact-measure-u-aim-a-new-patient-reported-tool
#19
Marcus Maurer, Susan D Mathias, Ross D Crosby, Yamina Rajput, James L Zazzali
BACKGROUND: Chronic spontaneous urticaria (CSU), also known as chronic idiopathic urticaria (CIU), may produce hives, itch, and angioedema. The Urticaria Activity and Impact Measure (U-AIM) is a newly developed 9-item patient-reported measure designed for use in routine clinical practice to assess CSU activity and impact over the previous 7 days. OBJECTIVE: To evaluate validity, responsiveness, and clinically meaningful change of the U-AIM. METHODS: Data from a 24-week open-label single-arm period of a randomized, placebo-controlled study of omalizumab were used to assess the psychometric properties of U-AIM items for itch, hives, and angioedema...
March 19, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29567358/short-term-lxr-activation-improves-epidermal-barrier-features-in-mild-to-moderate-atopic-dermatitis-a-randomized-controlled-trial
#20
Tali Czarnowicki, Anders B Dohlman, Kunal Malik, Diane Antonini, Robert Bissonnette, Tom C Chan, Lisa Zhou, Huei-Chi Wen, Yeriel Estrada, Hui Xu, Catherine Bryson, Jie Shen, Deepak Lala, Avi Ma'ayan, Gerard McGeehan, Richard Gregg, Emma Guttman-Yassky
No abstract text is available yet for this article.
March 19, 2018: Annals of Allergy, Asthma & Immunology
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