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Annals of Allergy, Asthma & Immunology

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https://www.readbyqxmd.com/read/28284980/the-kingston-allergy-birth-cohort-exploring-parentally-reported-respiratory-outcomes-through-the-lens-of-the-exposome
#1
Michelle L North, Jeffrey R Brook, Elizabeth Y Lee, Vanessa Omana, Nadia M Daniel, Lisa M Steacy, Greg J Evans, Miriam L Diamond, Anne K Ellis
BACKGROUND: The Kingston Allergy Birth Cohort (KABC) is a prenatally recruited cohort initiated to study the developmental origins of allergic disease. Kingston General Hospital was chosen for recruitment because it serves a population with notable diversity in environmental exposures relevant to the emerging concept of the exposome. OBJECTIVES: To establish a profile of the KABC using the exposome framework and examine parentally reported respiratory symptoms to 2 years of age...
March 8, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28284979/effect-of-polymorphisms-on-tgfb1-on-allergic-asthma-and-helminth-infection-in-an-african-admixed-population
#2
Ryan Dos Santos Costa, Camila Alexandrina Figueiredo, Maurıcio Lima Barreto, Neuza Maria Alcantara-Neves, Laura Cunha Rodrigues, Alvaro A Cruz, Candelaria Vergara, Nicholas Rafaels, Cassandra Foster, Joseph Potee, Monica Campbell, Rasika A Mathias, Kathleen C Barnes
BACKGROUND: Allergic asthma is a complex disorder that results from a combination of genetic and environmental factors. Studies suggest that helminth infections can activate a regulatory network characterized by the production of regulatory cytokines, such as interleukin 10 and transforming growth factor β1 (TGF-β1) and subsequently protect against immune-mediated diseases, such as asthma. On the other hand, TGF-β1 is increased in the lungs of individuals with asthma and may modulate airway inflammation...
March 8, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28284978/sustained-response-of-recombinant-human-c1-esterase-inhibitor-for-acute-treatment-of-hereditary-angioedema-attacks
#3
Jonathan A Bernstein, Anurag Relan, Joseph R Harper, Marc Riedl
BACKGROUND: Symptoms of hereditary angioedema (HAE) attacks can recur soon after initial treatment; the durability of response for recombinant human C1 esterase inhibitor (rhC1INH) treatment is unknown. OBJECTIVE: To examine the efficacy and durability of rhC1INH for acute HAE attacks. METHODS: In this pooled post hoc analysis of 2 trials, patients with type I or II HAE (functional C1INH levels <50% of normal) and a baseline visual analog scale score of at least 50 mm were included if they had received at least 1 intravenous dose of 50 U/kg of rhC1INH...
March 8, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28284977/mesalamine-desensitization-in-a-patient-with-treatment-refractory-ulcerative-colitis-and-aspirin-and-nonsteroidal-anti-inflammatory-drug-hypersensitivity
#4
Jordan L Heath, Ryan D Heath, Cyrus Tamboli, Larry Johnson, Ashley S Wilson, Sheva Chervinskiy, Matthew C Bell, Joshua L Kennedy
No abstract text is available yet for this article.
March 8, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28283278/sex-differences-in-the-efficacy-safety-and-tolerability-of-omalizumab-after-1-year-in-maltese-patients-with-asthma
#5
Caroline Gouder, Rachelle Asciak, Stephen Montefort
No abstract text is available yet for this article.
March 7, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28283277/anabolic-androgen-use-in-the-management-of-hereditary-angioedema-not-so-cheap-after-all
#6
Kevin Y Tse, Bruce L Zuraw, Qiaoling Chen, Sandra C Christiansen
BACKGROUND: Hereditary angioedema due to C1 inhibitor deficiency (HAE) is a rare, life-threatening disease that imposes a significant burden on affected patients. 17α-alkylated androgens (anabolic androgens) decrease attack frequency and severity but carry the risk of potentially serious dose-related adverse effects. Despite the emergence of targeted therapies for HAE, continued anabolic androgen use has been driven in part by their low cost. OBJECTIVE: To examine the hidden cost of anabolic androgen use related to the risk of developing non-HAE comorbidities...
March 7, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28283276/survey-of-pediatric-trainee-knowledge-dose-concentration-and-route-of-epinephrine
#7
Daniel J Scherzer, Nnenna O Chime, Nancy M Tofil, Melinda Fiedor Hamilton, Karambir Singh, Rachel M Stanley, Jennifer Kline, LeAnn M McNamara, Michael A Rosen, Elizabeth A Hunt
No abstract text is available yet for this article.
March 7, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28279594/blindness-tetraspasticity-and-other-signs-of-irreversible-brain-damage-in-hereditary-angioedema
#8
Konrad Bork, Randolf Brehler, Günther Witzke, Stephan Boor, Wolf Heineke, Jochen Hardt
No abstract text is available yet for this article.
March 6, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28274734/the-pd20-but-not-the-pc20-in-a-methacholine-challenge-test-is-device-independent
#9
Allan L Coates, Sharon D Dell, Donald W Cockcroft, Gail M Gauvreau
No abstract text is available yet for this article.
March 5, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28274733/apolipoprotein-b-a-possible-new-biomarker-for-anaphylaxis
#10
Maria Eleonore Pettersson, Gerard H Koppelman, Bertine M J Flokstra-de Blok, Cornelia Doriene van Ginkel, Caroline Roozendaal, Anneke C Muller-Kobold, Boudewijn J Kollen, Anthony E J Dubois
No abstract text is available yet for this article.
March 5, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28268134/physical-activity-restrictions-in-activity-and-body-mass-index-among-urban-children-with-persistent-asthma
#11
Heather Holderness, Nancy Chin, Deborah J Ossip, Maria Fagnano, Marina Reznik, Jill S Halterman
BACKGROUND: Asthma and obesity are public health problems that disproportionately affect underserved children. Urban children with asthma may be limited in their participation in physical activity, further increasing their risk for overweight. OBJECTIVE: To determine the prevalence of overweight and obesity among high-risk children with persistent asthma, to assess physical activity and activity restrictions by level of asthma control, and to evaluate whether activity is associated with weight status...
March 4, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28259391/sarcoidosis-of-the-ocular-adnexa
#12
Bipasha Mukherjee, Asra Ambreen, Md Shahid Alam
No abstract text is available yet for this article.
March 2, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28259390/evaluation-of-the-risk-of-infection-associated-with-subcutaneous-allergen-immunotherapy-american-academy-of-allergy-asthma-and-immunology-and-american-college-of-allergy-asthma-and-immunology-national-surveillance-study-on-allergen-immunotherapy-2014-2015
#13
Tolly G Epstein, Gary M Liss, Karen Murphy-Berendts, David I Bernstein
No abstract text is available yet for this article.
March 1, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28259389/idiopathic-avascular-necrosis-associated-with-humoral-deficiency
#14
Erica A Giraldi, John Johnson, Haig Tcheurekdjian, Robert W Hostoffer
No abstract text is available yet for this article.
March 1, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28256307/efficacy-and-safety-of-budesonide-formoterol-pmdi-vs-budesonide-pmdi-in-asthmatic-children-6-12-years
#15
David S Pearlman, Göran Eckerwall, Julie McLaren, Rosa Lamarca, Margareta Puu, Ileen Gilbert, Carin Jorup, Kristina Sandin, Miguel J Lanz
BACKGROUND: The efficacy and safety of budesonide/formoterol pressurized metered-dose inhaler (pMDI) have been demonstrated in patients with asthma at least 12 years old. OBJECTIVE: To evaluate the efficacy of 2 formoterol doses added to budesonide as fixed combinations vs budesonide alone in children 6 to younger than 12 years with asthma. METHODS: This randomized, double-blinded, parallel-group, multicenter study (NCT02091986; CHASE 3) included children 6 to younger than 12 years with asthma previously receiving a medium-dose inhaled corticosteroid (ICS) or an ICS plus a long-acting β2-agonist...
February 27, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28254204/eosinophilia-associated-with-strongyloides-infection-severe-asthma-and-central-bronchiectasis
#16
Kishan Shah, Denisa Ferastraoaru, Sunit Jariwala
No abstract text is available yet for this article.
February 18, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28254203/factors-associated-with-poor-controller-medication-use-in-children-with-high-asthma-emergency-department-use
#17
Arlene Butz, Tricia Morphew, Cassia Lewis-Land, Joan Kub, Melissa Bellin, Jean Ogborn, Shawna S Mudd, Mary Elizabeth Bollinger, Mona Tsoukleris
BACKGROUND: Understanding health and social factors associated with controller medication use in children with high-risk asthma may inform disease management in the home and community. OBJECTIVE: To examine health and social factors associated with the Asthma Medication Ratio (AMR), a measure of guideline-based care and controller medication use, in children with persistent asthma and frequent emergency department (ED) use. METHODS: Study questionnaires, serum allergen sensitization, salivary cotinine, and pharmacy record data were collected for 222 children enrolled from August 2013 to February 2016 in a randomized clinical trial that tested the efficacy of an ED- and home-based intervention...
February 18, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28254202/predictors-of-granulomatous-lymphocytic-interstitial-lung-disease-in-common-variable-immunodeficiency
#18
Stella Hartono, Megan S Motosue, Shakila Khan, Vilmarie Rodriguez, Vivek N Iyer, Rohit Divekar, Avni Y Joshi
BACKGROUND: A subset of patients with common variable immunodeficiency (CVID) develop granulomatous lymphocytic interstitial lung disease (GLILD), which is associated with early mortality. OBJECTIVE: To determine a set of clinical and/or laboratory parameters that correlate with GLILD. METHODS: A retrospective, nested case-control (patients with CVID diagnosed with GLILD compared with patients with CVID without a diagnosis of GLILD) medical record review was undertaken at Mayo Clinic, Rochester, MN...
February 18, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28214133/dynamic-hyperinflation-in-patients-with-asthma-and-exercise-induced-bronchoconstriction
#19
Olga Mediano, Raquel Casitas, Carlos Villasante, Elisabet Martínez-Cerón, Raúl Galera, Ester Zamarrón, Francisco García-Río
BACKGROUND: Little is known about the behavior of operative lung volumes during exercise in patients with asthma and exercise-induced bronchoconstriction (EIB). OBJECTIVES: To compare the presence of dynamic hyperinflation (DH) in patients with mild asthma with and without EIB and in healthy individuals and to relate the changes in end-expiratory lung volume (EELV) with postexercise airflow reduction. METHODS: A total of 122 consecutive stable patients (>12 years of age) with mild asthma and 38 controls were studied...
February 14, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28209319/erratum
#20
(no author information available yet)
No abstract text is available yet for this article.
February 10, 2017: Annals of Allergy, Asthma & Immunology
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