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Anesthesia and Analgesia

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https://www.readbyqxmd.com/read/28333707/the-effect-of-sedation-on-cortical-activation-a-randomized-study-comparing-the-effects-of-sedation-with-midazolam-propofol-and-dexmedetomidine-on-auditory-processing
#1
Michael A Frölich, Catiffaney Banks, Timothy J Ness
BACKGROUND: Every day, millions of people undergo surgical procedures facilitated by anesthesia. Yet, there is no clinically accepted measure to predict the effects of sedation or anesthesia on the central nervous system. Auditory brain activation may provide an objective and quantifiable method to measure of the effects of sedation on neuronal processing. METHODS: This is a randomized clinical trial. Forty-eight healthy volunteers were randomly assigned to receive 1 of 3 sedative drugs (midazolam [n = 11], propofol [n = 12], or dexmedetomidine [n = 12]) at a concentration adjusted to achieve mild sedation by self-rating, or to a no-drug control group (n = 13)...
March 22, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28333706/video-based-physiologic-monitoring-during-an-acute-hypoxic-challenge-heart-rate-respiratory-rate-and-oxygen-saturation
#2
Paul S Addison, Dominique Jacquel, David M H Foo, André Antunes, Ulf R Borg
BACKGROUND: The physiologic information contained in the video photoplethysmogram is well documented. However, extracting this information during challenging conditions requires new analysis techniques to capture and process the video image streams to extract clinically useful physiologic parameters. We hypothesized that heart rate, respiratory rate, and oxygen saturation trending can be evaluated accurately from video information during acute hypoxia. METHOD: Video footage was acquired from multiple desaturation episodes during a porcine model of acute hypoxia using a standard visible light camera...
March 22, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28333705/inhaled-remimazolam-potentiates-inhaled-remifentanil-in-rodents
#3
Tatjana Bevans, Cassandra Deering-Rice, Chris Stockmann, Joseph Rower, Derek Sakata, Christopher Reilly
BACKGROUND: Remimazolam is an ester-based short-acting benzodiazepine currently in clinical trials for IV administration. This study explored the feasibility of delivering remimazolam alone and as an adjunct to remifentanil via inhalation in rodent models. METHODS: Mice were exposed to remimazolam via inhalation; sedation was assessed using time to movement outside a set perimeter. Rats were also exposed to remimazolam aerosol alone and in combination with inhaled remifentanil, and analgesia was quantified by using a tail flick meter...
March 22, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28333704/massive-transfusion-in-cardiac-surgery-the-impact-of-blood-component-ratios-on-clinical-outcomes-and-survival
#4
Meghan Delaney, Paul C Stark, Minhyung Suh, Darrell J Triulzi, John R Hess, Marie E Steiner, Christopher P Stowell, Steven R Sloan
BACKGROUND: Cardiac surgery is the most common setting for massive transfusion in medically advanced countries. Studies of massive transfusion after injury suggest that the ratios of administered plasma and platelets (PLT) to red blood cells (RBCs) affect mortality. Data from the Red Cell Storage Duration Study (RECESS), a large randomized trial of the effect of RBC storage duration in patients undergoing complex cardiac, were analyzed retrospectively to investigate the association between blood component ratios used in massively transfused patients and subsequent clinical outcomes...
March 22, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28333703/higher-fresh-gas-flow-rates-decrease-tidal-volume-during-pressure-control-ventilation
#5
Shazia Mohammad, Nikolaus Gravenstein, Drew Gonsalves, Terrie Vasilopoulos, Samsun Lampotang
BACKGROUND: We observed that increasing fresh gas flow (FGF) decreased exhaled tidal volume (VT) during pressure control ventilation (PCV). A literature search produced no such description whereby unintended VT changes occur with FGF changes during PCV. METHODS: To model an infant's lungs, 1 lung of a mechanical lung model (Dual Adult TTL 1600; Michigan Instruments, Inc, Grand Rapids, MI) was set at a compliance of 0.0068 L/cm H2O. An Rp50 resistor (27.2 cm H2O/L/s at 15 L/min) simulated normal bronchial resistance...
March 22, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28333702/anesthesia-review-blasting-the-boards
#6
Jue T Wang, Craig D McClain
No abstract text is available yet for this article.
March 22, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28333701/patient-blood-management
#7
Weiyun Chen, Steven M Frank
No abstract text is available yet for this article.
March 22, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28328759/topical-ropivacaine-in-prevention-of-post-tonsillectomy-pain-in-adults
#8
Hanna Kaisa Tolska, Annika Takala, Karin Blomgren, Katri Hamunen, Vesa Kontinen
BACKGROUND: Post-tonsillectomy pain is 1 of the most intense postoperative pain conditions. However, optimal and sufficient postoperative analgesic treatment remains unclear. We investigated the effect of topical ropivacaine for post-tonsillectomy pain in 160 adult outpatient surgery patients over 2 postoperative weeks. METHODS: At the end of tonsillectomy, 2 swabs soaked in either 1% ropivacaine or saline were packed into the tonsillar beds for 5 minutes. We used ibuprofen and a combination of acetaminophen (500 mg)-codeine (30 mg) tablets as postoperative analgesics for 2 weeks...
March 21, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28328758/posttransfusion-increase-of-hematocrit-per-se-does-not-improve-circulatory-oxygen-delivery-due-to-increased-blood-viscosity
#9
Robert Zimmerman, Amy G Tsai, Beatriz Y Salazar Vázquez, Pedro Cabrales, Axel Hofmann, Jens Meier, Aryeh Shander, Donat R Spahn, Joel M Friedman, Daniel M Tartakovsky, Marcos Intaglietta
BACKGROUND: Blood transfusion is used to treat acute anemia with the goal of increasing blood oxygen-carrying capacity as determined by hematocrit (Hct) and oxygen delivery (DO2). However, increasing Hct also increases blood viscosity, which may thus lower DO2 if the arterial circulation is a rigid hydraulic system as the resistance to blood flow will increase. The net effect of transfusion on DO2 in this system can be analyzed by using the relationship between Hct and systemic blood viscosity of circulating blood at the posttransfusion Hct to calculate DO2 and comparing this value with pretransfusion DO2...
March 21, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28328757/in-response
#10
Markus M Luedi, Dietrich Doll, Steven D Boggs, Frank Stueber
No abstract text is available yet for this article.
March 21, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28328756/pectoralis-and-serratus-fascial-plane-blocks-each-provide-early-analgesic-benefits-following-ambulatory-breast-cancer-surgery-a-retrospective-propensity-matched-cohort-study
#11
Faraj W Abdallah, David MacLean, Caveh Madjdpour, Tulin Cil, Anuj Bhatia, Richard Brull
BACKGROUND: Pectoralis and serratus blocks have been described recently for use in breast surgery, but evidence supporting their analgesic benefits is limited. This cohort study evaluates the benefits of adding a pectoralis or serratus block to conventional opioid-based analgesia (control) in patients who underwent ambulatory breast cancer surgery at Women's College Hospital between July 2013 and May 2015. We tested the joint hypothesis that adding a pectoralis or serratus block reduced postoperative in-hospital (predischarge) opioid consumption and nausea and vomiting (PONV)...
March 21, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28328755/atlas-of-anatomy-thieme-anatomy-pragmatic-simplicity
#12
Anna Puigdellívol-Sánchez, Miguel A Reina, Alberto Prats-Galino
No abstract text is available yet for this article.
March 21, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28328754/in-response
#13
Christopher Varga, Nikolaus Gravenstein, Isaac Luria
No abstract text is available yet for this article.
March 21, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28328753/research-methodology-the-aims-practices-and-ethics-of-science
#14
David B Glick
No abstract text is available yet for this article.
March 21, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28328752/venous-air-embolism-the-severity-depends-on-many-factors
#15
Yafen Liang, Mark J Rice
No abstract text is available yet for this article.
March 21, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28328751/an-improvement-on-central-line-dressings-using-an-omental-technique
#16
Zeb M McMillan, Christopher R Tainter
No abstract text is available yet for this article.
March 21, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28328750/why-is-it-surprising-that-emotional-intelligence-matters
#17
Burkhard Spiekermann
No abstract text is available yet for this article.
March 21, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28328749/pediatric-anesthesiology-a-comprehensive-board-review
#18
Peggy A Seidman
No abstract text is available yet for this article.
March 21, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28319519/process-improvement-initiative-for-the-perioperative-management-of-patients-with-a-cardiovascular-implantable-electronic-device
#19
Margaret K Menzel Ellis, Miriam M Treggiari, Jamie M Robertson, Marc A Rozner, Peter F Graven, Michael F Aziz, Matthias J Merkel, Edward A Kahl, Norman A Cohen, Eric C Stecker, Peter M Schulman
BACKGROUND: Economic, personnel, and procedural challenges often complicate and interfere with efficient and safe perioperative care of patients with cardiovascular implantable electronic devices (CIEDs). In the context of a process improvement initiative, we created and implemented a comprehensive anesthesiologist-run perioperative CIED service to respond to all routine requests for perioperative CIED consultations at a large academic medical center. This study was designed to determine whether this new care model was associated with improved operating room efficiency, reduced institutional cost, and adequate patient safety...
March 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28319518/irony-and-the-elephant-in-the-review
#20
Hilary P Grocott, Raymond Deutscher
No abstract text is available yet for this article.
March 17, 2017: Anesthesia and Analgesia
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