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American Journal of Ophthalmology

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https://www.readbyqxmd.com/read/30503014/reply
#1
LETTER
Robert A Clark, Joseph L Demer
No abstract text is available yet for this article.
November 28, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30502338/assessment-of-circumferential-angle-closure-with-swept-source-optical-coherence-tomography-a-community-based-study
#2
Natalia Porporato, Mani Baskaran, Tin A Tun, Rehena Sultana, Marcus Cl Tan, Joanne Hm Quah, John Allen, David S Friedman, Ching-Yu Cheng, Tin Aung
PURPOSE: To evaluate the diagnostic performance of swept-source optical coherence tomography (SS-OCT, CASIA SS-1000, Tomey Corporation, Nagoya, Japan) for angle closure detection, in comparison with gonioscopy in a community setting. DESIGN: Reliability analysis. METHODS: A total of 2027 phakic subjects aged ≥50 years, with no previous history of glaucoma, laser (including peripheral iridotomy), intraocular surgery or ocular trauma, were consecutively recruited from a community polyclinic in Singapore...
November 28, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30502337/changes-in-ganglion-cell-inner-plexiform-layer-thickness-and-retinal-microvasculature-in-hypertension-an-oct-angiography-study
#3
Hyung Bin Lim, Min Woo Lee, Jae Hyeong Park, Kyeung Min Kim, Young Joon Jo, Jung Yeul Kim
OBJECTIVE: To investigate retinal blood flow in patients with hypertension using optical coherence tomography angiography (OCTA) and the relationship between blood flow metrics and ganglion cell-inner plexiform layer (GC-IPL) thickness. DESIGN: Retrospective, cross-sectional study. METHODS: A total of 201 eyes from 117 healthy subjects and 84 hypertensive patients without any ocular abnormalities were included. Hypertensive patients were divided into the two groups according to disease periods (<5 years: hypertension group 1; ≥5 years: hypertension group 2)...
November 28, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30502336/international-board-members-of-the-american-journal-of-ophthalmology
#4
Andrzej Grzybowski, Piotr Kanclerz
This year marks the 100th anniversary of the "modern" American Journal of Ophthalmology (AJO). International influence was present since the beginnings of the journal, and AJO had several foreign editorial board members and collaborators. Within the article we present sketches of the deceased international board members of the AJO, particularly of Sir Stewart Duke-Elder, Pierre Amalric, Joaquin Barraquer and Yasuo Tano. Although AJO is American by name and by majority of contributions and readers, the international board members and collaborators helped to maintain its international character and its world-wide recognition...
November 28, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30502335/clinical-and-biological-factors-associated-with-recurrences-of-severe-toxoplasmic-retinochoroiditis-confirmed-by-aqueous-humor-analysis
#5
Alexandre Matet, Luc Paris, Christine Fardeau, Céline Terrada, Emmanuelle Champion, Arnaud Fekkar, Nathalie Cassoux, Valérie Touitou, Phuc LeHoang, Bahram Bodaghi
PURPOSE: To investigate clinical and biological factors influencing recurrences of severe toxoplasmic retinochoroiditis (TRC) confirmed by aqueous humor analysis. DESIGN: Retrospective case series. METHODS: Retrospective analysis of 87 subjects with severe TRC, proven by positive Goldmann-Witmer coefficient (GWC), Toxoplasma gondii (T.gondii) immunoblot, or T.gondii-specific polymerase chain reaction (PCR) in aqueous humor. Cases with immunosuppression or retinal scars without previous recorded episode were excluded...
November 28, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30502334/clinical-outcomes-of-descemet-membrane-endothelial-keratoplasty-in-eyes-with-a-glaucoma-drainage-device
#6
Rénuka S Birbal, C Maya Tong, Isabel Dapena, John S Parker, Jack S Parker, Silke Oellerich, Gerrit R J Melles
PURPOSE: To evaluate the feasibility and clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK) in eyes with a glaucoma drainage device (GDD). DESIGN: Retrospective, interventional case series. METHODS: Clinical outcomes of 23 DMEK procedures for bullous keratopathy (52%), failed previous transplant (39%) or Fuchs endothelial corneal dystrophy (9%) in 20 eyes (19 patients) with a GDD were retrospectively analyzed at two tertiary referral centers...
November 28, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30502042/re-magnetic-resonance-imaging-of-the-globe-tendon-interface-for-extraocular-muscles-is-there-an-arc-of-contact
#7
LETTER
Joel M Miller, Alan B Scott
No abstract text is available yet for this article.
November 27, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30496723/macula-vessel-density-and-thickness-in-early-primary-open-angle-glaucoma
#8
Huiyuan Hou, Sasan Moghimi, Linda M Zangwill, Takuhei Shoji, Elham Ghahari, Rafaella C Penteado, Tadamichi Akagi, Patricia Isabel C Manalastas, Robert N Weinreb
PURPOSE: To characterize and compare the ganglion cell complex (GCC) thickness and macula vessel density in pre-perimetric and early primary open angle glaucoma (POAG) eyes. DESIGN: Cross-sectional study. METHODS: 57 healthy eyes, 68 pre-perimetric and 162 early POAG eyes enrolled in the Diagnostic Innovations in Glaucoma Study. Optical coherence tomography angiography (OCT-A) based superficial macula vessel density and OCT based GCC thickness were evaluated simultaneously...
November 26, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30477751/conbercept-for-treatment-of-neovascular-age-related-macular-degeneration-results-of-the-randomized-phase-3-phoenix-study
#9
LETTER
Kun Liu, Xun Xu
No abstract text is available yet for this article.
November 23, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30471242/assessment-of-the-impact-of-an-endpoint-committee-in-the-ocular-hypertension-treatment-study
#10
Mae O Gordon, Eve J Higginbotham, Dale K Heuer, Richard K Parrish, Alan L Robin, Patricia A Morris, Deborah A Dunn, Bradley S Wilson, Michael A Kass
PURPOSE: To assess the impact of a masked Endpoint Committee on estimates of the incidence of primary open angle glaucoma (POAG), treatment efficacy and statistical power of the Ocular Hypertension Treatment Study-Phase 1, 1994-2002 (OHTS-1). DESIGN: Retrospective inter-rater reliability analysis of endpoint attribution by the Endpoint Committee METHODS: After study closeout, we re-calculated estimates of endpoint incidence, treatment efficacy and statistical power using all-cause endpoints and POAG endpoints...
November 21, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30471241/comparison-of-topical-5-fluorouracil-and-interferon-alfa-2b-as-primary-treatment-modalities-for-ocular-surface-squamous-neoplasia
#11
Nandini Venkateswaran, Carolina Mercado, Anat Galor, Carol L Karp
PURPOSE: To compare the efficacy of topical 5-fluorouracil 1% (5FU) and interferon alfa-2b 1 MIU/mL (IFN) eye drops as primary treatment modalities for ocular surface squamous neoplasia (OSSN). DESIGN: Retrospective, comparative, interventional case series. METHODS: Fifty-four patients who received 5FU and 48 patients who received IFN as primary therapy for OSSN were included. Primary outcome measures were the frequency of clinical resolution and time to OSSN recurrence by treatment modality...
November 21, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30465746/early-detection-of-glaucomatous-visual-field-progression-using-pointwise-linear-regression-with-binomial-test-in-the-central-10-degrees
#12
Shotaro Asano, Hiroshi Murata, Masato Matsuura, Yuri Fujino, Ryo Asaoka
PURPOSE: We previously reported that it was beneficial to apply binomial pointwise linear regression (PLR) to detect 24-2 glaucomatous visual field (VF) progression, compared to mean deviation (MD) trend analysis and permutation analysis of PLR (PoPLR). The purpose of the current study was to validate the usefulness of the binomial PLR method to detect VF progression in the central 10 degrees in glaucoma patients. DESIGN: Reliability assessment. METHODS: A series of 15 VFs (Humphrey Field Analyzer 10-2 SITA-standard) from 97 eyes in 69 primary open-angle glaucoma, obtained over 8...
November 19, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30448463/en-face-optical-coherence-tomography-imaging-of-the-photoreceptor-layers-in-hydroxychloroquine-retinopathy
#13
Seong Joon Ahn, Jooyoung Joung, Byung Ro Lee
OBJECTIVE: To investigate the application of en face optical coherence tomography (OCT) imaging in eyes with hydroxychloroquine (HCQ) retinopathy. DESIGN: Retrospective case series METHODS: SETTING: Institutional PATIENT POPULATION: Sixty-two eyes of 31 Asian patients with HCQ retinopathy. OBSERVATION PROCEDURES: Macular volume scanning using swept-source OCT was performed in 6 × 6 and 9 × 9 mm areas centered on the fovea. Segmentation of the photoreceptor layers was automatically performed between the inner border of the ellipsoid zone and that of the retinal pigment epithelium-Bruch's membrane complex to obtain en face OCT images...
November 15, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30448306/boston-type-i-keratoprosthesis-antibacterial-resistance-and-microbiota-evaluation-of-soft-contact-lenses
#14
LETTER
Pranita Sahay, Ritu Nagpal, Deepali Singhal, Prafulla K Maharana
No abstract text is available yet for this article.
November 15, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30448305/antibiotic-resistance-induction-in-eyes-with-boston-type-i-keratoprosthesis
#15
LETTER
Emilio A Torres-Netto, Luzia Diegues Silva, Marco Antonio Bordon Riveros, Albert Santos, Luciene B Sousa, Lauro A Oliveira
No abstract text is available yet for this article.
November 15, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30419194/amniotic-membrane-transplantation-in-acute-severe-ocular-chemical-injury-a-randomized-clinical-trial
#16
Medi Eslani, Alireza Baradaran-Rafii, Albert Y Cheung, Khaliq H Kurji, Hamidreza Hasani, Ali R Djalilian, Edward J Holland
PURPOSE: To compare the outcomes of conventional medical treatment versus combined medical treatment and amniotic membrane transplantation (AMT) in the management of patients with Roper-Hall grade IV ocular chemical injury. DESIGN: Randomized, parallel-controlled clinical trial METHODS: Setting: Single tertiary referral hospital. PATIENTS: 60 eyes of 60 patients with Roper-Hall grade IV ocular chemical injury with a minimum follow-up of 12 months were enrolled in the study...
November 9, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30419193/orbital-lymphoma-an-international-multicenter-retrospective-study
#17
Tine Gadegaard Olsen, Frederik Holm, Lauge Hjorth Mikkelsen, Peter Kristian Rasmussen, Sarah E Coupland, Bita Esmaeli, Paul T Finger, Gerardo F Graue, Hans E Grossniklaus, Santosh G Honavar, Jwu Jin Khong, Penelope A McKelvie, Kaustubh Mulay, Lene Dissing Sjö, Geeta K Vemuganti, Bradley A Thuro, Steffen Heegaard
PURPOSE: To investigate and characterize the clinical features of subtype-specific orbital lymphoma. DESIGN: Retrospective, interventional case series. METHODS: The study included 7 international eye cancer centers. Patient data were collected from January 1, 1980 through December 31, 2017. A total of 797 patients with a histologically verified orbital lymphoma were included. The primary end points were overall survival, disease-specific survival and progression-free survival...
November 9, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30414397/glaucoma-specialist-detection-of-optical-coherence-tomography-suspicious-rim-tissue-in-glaucoma-and-glaucoma-suspect-eyes
#18
Seung Woo Hong, Helen Koenigsman, Hongli Yang, Ruojin Ren, Juan Reynaud, Robert M Kinast, Steven L Mansberger, Brad Fortune, Shaban Demirel, Stuart K Gardiner, Claude F Burgoyne
PURPOSE: To assess glaucoma specialists' detection of optic nerve head (ONH) rim tissue that is thin by optical coherence tomography (OCT) criteria. DESIGN: Reliability analysis METHODS: 5 clinicians marked the disc margin (DM) and rim margin (RM) on stereo-photos of 151 glaucoma or glaucoma suspect eyes obtained within 3 months of OCT imaging. The photo and OCT infrared image for each eye were colocalized and regionalized into twelve sectors relative to the axis between Bruch's membrane opening (BMO) centroid and the fovea...
November 7, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30401482/conbercept-for-treatment-of-neovascular-age-related-macular-degeneration-results-of-the-randomized-phase-3-phoenix-study
#19
LETTER
Dan Călugăru, Mihai Călugăru
No abstract text is available yet for this article.
November 3, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30391530/incidence-and-outcomes-of-intraoperative-descemet-membrane-perforations-during-deep-anterior-lamellar-keratoplasty
#20
Olivia S Huang, Hla M Htoon, Amy M Chan, Donald Tan, Jodhbir S Mehta
PURPOSE: To report the incidence and outcomes of intraoperative Descemet membrane (DM) perforations during deep anterior lamellar keratoplasty (DALK). DESIGN: Retrospective, consecutive, interventional case series. METHODS: A retrospective audit of all DALK cases performed from 2004 to 2015 in a tertiary centre, with and without intraoperative DM perforations. We excluded cases with pre-existing corneal perforations before surgery. RESULTS: There were a total of 540 eyes, of which 101 (18...
October 31, 2018: American Journal of Ophthalmology
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