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American Journal of Ophthalmology

Rohit Varma, Mina Torres, Roberta McKean-Cowdin, Fen Rong, Chunyi Hsu, Xuejuan Jiang
PURPOSE: To estimate the prevalence of refractive errors in adult Chinese Americans, and evaluate factors associated with myopia and high myopia. DESIGN: A population-based, cross-sectional study. METHODS: Chinese Americans 50 years and older residing in Monterey Park, California, were recruited. Noncycloplegic automated refraction with supplemental subjective refraction was performed. Myopia, high myopia, hyperopia, and high hyperopia were defined as a spherical equivalent of < -0...
October 18, 2016: American Journal of Ophthalmology
Saumya Sharma, Ashi Khurana, Azad G Bansal
No abstract text is available yet for this article.
October 17, 2016: American Journal of Ophthalmology
Ting Huang, Chen Ouyang, Chao Hou, Qianni Wu, Yunwei Hu
No abstract text is available yet for this article.
October 17, 2016: American Journal of Ophthalmology
Melinda Y Chang, Andrew Shin, Joseph Park, Aaron Nagiel, Robert A Lalane, Steven D Schwartz, Joseph L Demer
PURPOSE: To ascertain deformation of the optic nerve head (ONH) and peripapillary tissues caused by horizontal duction. DESIGN: Prospective, experimental study. METHODS: Optical coherence tomography of the ONH region was performed in 23 eyes of twelve normal volunteers in central gaze and increasing (10, 20, and 30°) adduction and abduction. Main outcome measures were changes from central gaze in the configuration of the ONH and peripapillary tissues in eccentric gazes...
October 14, 2016: American Journal of Ophthalmology
Juan Carlos Serna-Ojeda, Denise Loya-Garcia, Alejandro Navas, Alejandro Lichtinger, Arturo Ramirez-Miranda, Enrique O Graue-Hernandez
PURPOSE: To analyze the characteristics and long-term outcomes of patients that underwent pediatric penetrating keratoplasty (PPK) for herpes simplex virus (HSV) keratitis. DESIGN: Retrospective, interventional, consecutive case series. METHODS: Observational report of outcomes and findings. Nine patients with history of HSV keratitis that underwent PPK and were followed in a single institution. Difference between the median preoperative and final best-corrected visual acuity (BCVA) was assessed and the outcomes are reported...
October 13, 2016: American Journal of Ophthalmology
Maria Eleftheriadou, Clara Vazquez-Alfageme, Cristina Maria Citu, Roxanne Crosby-Nwaobi, Sobha Sivaprasad, Philip Hykin, Robin D Hamilton, Praveen J Patel
PURPOSE: To report 2 year treatment outcomes with intravitreal aflibercept for neovascular age-related macular degeneration (nAMD) in routine clinical practice. DESIGN: Retrospective, non-randomized, interventional case series. METHODS: Retrospective analysis of electronic medical record (EMR) notes (OpenEyes), paper case notes and review of spectral-domain optical coherence tomography (SD-OCT) imaging of patients with consecutively treated eyes with previously untreated nAMD...
October 13, 2016: American Journal of Ophthalmology
Uri Elbaz, Kamiar Mireskandari, Nasrin Tehrani, Carl Shen, Saad Khan, Sara Luck, Asim Ali
PURPOSE: To establish a normative database of endothelial cell density (ECD) using in-vivo specular microscopy in children under 5 years old. DESIGN: Cross sectional study. METHODS: Specular microscopy was performed during a clinic visit in cooperative children in the standard upright position. In uncooperative children, specular microscopy was performed in the lateral decubitus position under general anesthesia, prior to surgery for other reasons...
October 13, 2016: American Journal of Ophthalmology
Marissa B Larochelle, Ryan Phan, John Craddock, Mark J Abzug, Donna Curtis, Christine C Robinson, Roger H Giller, Shaun Cosgrove, Frank Siringo, Emily McCourt, Alan G Palestine
PURPOSE: The incidence of cytomegalovirus (CMV) retinitis in the pediatric allogeneic hematopoietic stem cell transplant (HSCT) population is unknown. We report a cluster of 5 pediatric patients with CMV retinitis diagnosed in a 12-month period, and compare this to the rate of CMV viremia and retinitis in the four years prior. Presented is the ophthalmic screening protocol developed in response to this experience. DESIGN: Retrospective cross-sectional study. METHODS: A retrospective chart review was performed on patients at Children's Hospital of Colorado (CHCO) who received allogeneic HSCT between January 2010 and December 2014...
October 13, 2016: American Journal of Ophthalmology
Carol L Shields, Adel E Alset, Nina S Boal, Mairghread G Casey, Austen N Knapp, Jordan A Sugarman, Marisa A Schoen, Phillip S Gordon, Alexzandra M Douglass, Kareem Sioufi, Emil A T Say, Jerry A Shields
PURPOSE: To evaluate frequency of conjunctival tumors in all ages and compare benign versus (vs) malignant counterparts. DESIGN: Retrospective series. METHODS: Setting: Tertiary referral center STUDY POPULATION: 5002 patients OBSERVATION: Clinical features MAIN OUTCOME MEASURE: Differentiation benign from malignant counterparts RESULTS: The tumor was benign (52%), premalignant (18%), or malignant (30%). Malignant tumors included melanoma (12%), squamous cell carcinoma (9%), lymphoma (7%), and others...
October 7, 2016: American Journal of Ophthalmology
Xiangjia Zhu, Wenwen He, Xinghuai Sun, Jinhui Dai, Yi Lu
No abstract text is available yet for this article.
October 6, 2016: American Journal of Ophthalmology
Charles C Wykoff, Ryan T Le, Rahul N Khurana, David M Brown, William C Ou, Rui Wang, W Lloyd Clark, David S Boyer
PURPOSE: To determine whether the efficacy and safety achieved with 2.0mg intravitreal aflibercept injections (IAI) for diabetic macular edema (DME) during the phase III VISTA DME trial were maintained with individualized, as-needed treatment. DESIGN: Phase IV, multicenter, open-label extension study. METHODS: Sixty patients completing VISTA DME elected to enter the ENDURANCE extension study. All patients received IAI in the presence of clinically relevant DME...
October 1, 2016: American Journal of Ophthalmology
Pelin Özyol, Erhan Özyol, Ercan Baldemir
PURPOSE: Since age-related changes in lens elasticity and ciliary muscle contractility can affect how ocular parameters respond to cycloplegia, intraocular lens (IOL) power measurements calculated by formulas using anterior chamber depth (ACD), lens thickness (LT) or white-to-white (WtW) for effective lens position prediction can vary. In response, using swept-source optical biometry in pre-presbyopic and presbyopic eyes, we investigated changes in ocular parameters and IOL power calculations due to cycloplegia...
October 1, 2016: American Journal of Ophthalmology
Katie M Hallahan, Brian Cost, Jeff M Goshe, William J Dupps, Sunil K Srivastava, Justis P Ehlers
PURPOSE: To correlate intraoperative interface fluid dynamics during Descemet stripping automated endothelial keratoplasty (DSAEK) surgery using intraoperative optical coherence tomography (iOCT) in the PIONEER (Prospective Intraoperative and Perioperative Ophthalmic ImagiNg with Optical CohEncE TomogRaphy) study with postoperative outcomes. DESIGN: Prospective consecutive, interventional, comparative case series PARTICIPANTS: One hundred and seventy-eight eyes of 173 patients undergoing DSAEK from the Cole Eye Institute, Cleveland, USA...
October 1, 2016: American Journal of Ophthalmology
Hyun Tae Kim, Joon Mo Kim, Jung Hoon Kim, Jae Hyuck Lee, Mi Yeon Lee, Jae Yeun Lee, Yu Sam Won, Ki Ho Park, Hyun Seok Kwon
PURPOSE: To evaluate the relationship between intraocular pressure (IOP) and various anthropometric measures. DESIGN: A population-based cross-sectional study. METHODS: Patients: A total of 5,008 participants, 2,080 men and 2,928 women, aged ≥19 years were included from the Korea National Health and Nutrition Examination Survey V database, focusing on the years 2010 and 2011. We selected IOP in the right eye of a normal healthy population as the outcome variable of our study...
October 1, 2016: American Journal of Ophthalmology
Osamah Saeedi, Hasan Ashraf, Eric P Slade, Deborah R Medoff, Lan Li, David S Friedman, Julie Kreyenbuhl
PURPOSE: To assess trends in prevalence of diagnosed ocular disease and utilization of eye care services in the VA healthcare system. DESIGN: Prevalence study METHODS: We performed a retrospective study of all eligible Veterans in the VA Capitol Health Care Network from 2007 to 2011. The VA database was used to abstract demographic and socioeconomic variables including age, race, gender, marital status, service connection, prescription copay, homelessness, VA facility...
October 1, 2016: American Journal of Ophthalmology
Giacomo Savini, Kenneth J Hoffer, Wolfgang Haigis
No abstract text is available yet for this article.
October 1, 2016: American Journal of Ophthalmology
Richard C Prielipp, Megan L Lanigan, David J Birnbach
No abstract text is available yet for this article.
October 1, 2016: American Journal of Ophthalmology
Lee Kiang, Mark W Johnson
PURPOSE: Cavitary optic disc maculopathy develops when fluctuating pressure gradients along anomalous communications in the optic nerve head induce migration of fluid into the adjacent retinal tissue. We sought to determine whether carefully titrated laser photocoagulation combined with vitrectomy and gas tamponade can safely create an effective intraretinal barrier to fluid egress from the optic disc cavitation. DESIGN: Retrospective interventional case series METHODS: We retrospectively evaluated medical records and imaging studies of 22 consecutive patients with cavitary disc maculopathy evaluated by a single surgeon between 1991 and 2014...
September 30, 2016: American Journal of Ophthalmology
Woong-Joo Whang, Young-Sik Yoo, Choun-Ki Joo, Geunyoung Yoon
PURPOSE: To analyze surgically induced refractive change (SIRC) and change in high-order aberration after Raindrop corneal inlay insertion, and assess the extent to which Raindrop corneal inlay insertion could correct presbyopia. DESIGN: Interventional case series. METHODS: 17 patients were included if they had a corneal thickness of 500 μm or greater and a stable manifest spherical equivalent refraction between -0.50 and +1.00 diopters.(D) The Raindrop corneal inlay (ReVision Optics, Lake Forest, CA) was implanted on the stromal bed of a femtosecond laser-assisted generated flap of non-dominant eyes...
September 30, 2016: American Journal of Ophthalmology
Nakul Singh, Jonathan S Chang, Aleksandra V Rachitskaya
PURPOSE: To analyze anti-vascular endothelial growth factor (anti-VEGF) agent-associated industry payments to ophthalmologists using the Centers for Medicare and Medicaid Services (CMS) Open Payments and Provider Utilization and Payment data. DESIGN: Retrospective database review using two national databases. METHODS: Payments from 2013 to 2014 were analyzed by anti-VEGF agent, payment category, and dollar amount. Ranibizumab and aflibercept usage was correlated by performing logratio analysis...
September 30, 2016: American Journal of Ophthalmology
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