journal
MENU ▼
Read by QxMD icon Read
search

American Journal of Ophthalmology

journal
https://www.readbyqxmd.com/read/28435054/experience-with-a-subretinal-cell-based-therapy-in-patients-with-geographic-atrophy-secondary-to-age-related-macular-degeneration
#1
Allen C Ho, Tom S Chang, Michael Samuel, Paul Williamson, Robert F Willenbucher, Terri Malone
PURPOSE: To evaluate the safety and tolerability of and clinical response to a single, subretinal dose of human umbilical tissue-derived cells (palucorcel [CNTO-2476]) in the eyes of adults aged ≥50 years with bilateral geographic atrophy (GA) secondary to age-related macular degeneration (AMD). DESIGN: Phase 1/2a, multicenter, open-label, dose-escalation, fellow-eye-controlled study. METHODS: In the phase 1 portion, eyes were assigned to receive a single, subretinal dose of palucorcel (ranging from 6...
April 20, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28428050/socioeconomic-disparity-in-global-burden-of-cataract-an-analysis-for-2013-with-time-trends-since-1990
#2
Lixia Lou, Jingyi Wang, Peifang Xu, Xin Ye, Juan Ye
PURPOSE: To assess socioeconomic disparity in global burden of cataract, by using disability-adjusted life years (DALYs). DESIGN: International, comparative burden-of-disease study. METHODS: Published data on national age-standardized DALY rates caused by cataract and human development index (HDI) between 1990 and 2013 were obtained. The association between age-standardized DALY rates and HDI in 2013 was analyzed. The health-related Gini coefficients and the concentration indexes were calculated to explore the trends in between-country inequality in cataract burden from 1990 to 2013...
April 17, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28428049/stem-cells-for-retinal-disease-a-perspective-on-the-promise-and-perils
#3
Rajesh C Rao, Vaidehi S Dedania, Mark W Johnson
PURPOSE: To summarize key concepts, and early safety and efficacy signals from clinical trials for stem/progenitor cell-based interventions for retinal disease. DESIGN: Interpretive essay. METHODS: Review and synthesis of selected recent reports of stem/progenitor cell-based approaches for retinal disease, with interpretation and perspective. RESULTS: Stem/progenitor cell-based interventions represent a novel class of potential therapies for retinal diseases, such as age-related macular degeneration, inherited retinal dystrophies, and others...
April 17, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28416175/corneal-endothelial-cell-density-in-children-normative-data-from-birth-to-5-years-old
#4
LETTER
Kenneth J Hoffer
No abstract text is available yet for this article.
April 14, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28414044/the-impact-of-the-medicare-access-and-chip-reauthorization-act-macra-on-the-field-of-ophthalmology
#5
Brenton Kinker, Kaitlyn Dobesh, Nariman Nassiri, Mark S Juzych, M Roy Wilson
PURPOSE: To analyze the impact of the Medicare Access and CHIP Reauthorization Act of 2015 (MACRA) on the field of ophthalmology. DESIGN: A perspective on the effects of MACRA's Quality Payment Program after analysis of the proposed rule, final rule, and commentary submitted by relevant stakeholders. RESULTS: Physicians will need to use one of two payment structures: Merit Based Incentive Payment Systems (MIPS), or Alternative Payment Models (APMs)...
April 13, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28414043/quality-of-life-outcomes-from-a-randomized-clinical-trial-comparing-antimetabolites-for-intermediate-posterior-and-panuveitis
#6
Katherine M Niemeyer, John A Gonzales, Sivakumar R Rathinam, Manohar Babu, Radhika Thundikandy, Anuradha Kanakath, Travis C Porco, Erica N Browne, Maya M Rao, Nisha R Acharya
PURPOSE: To evaluate the changes in quality of life in noninfectious uveitis patients treated with two of the most commonly prescribed antimetabolite treatments. DESIGN: Secondary analysis of a multicenter, block-randomized, clinical trial (ClinicalTrials.gov NCT01232920). METHODS: Eighty patients at Aravind Eye Hospitals in Madurai and Coimbatore, India, with noninfectious intermediate, posterior, or panuveitis were randomized to receive oral methotrexate, 25 mg weekly, or oral mycophenolate mofetil, 1 g twice daily, and were followed up monthly for 6 months...
April 13, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28411861/importance-of-accommodation-and-eye-dominance-for-measuring-objective-refractions
#7
LETTER
Yukari Tsuneyoshi, Kazuno Negishi, Kazuo Tsubota
No abstract text is available yet for this article.
April 12, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28411860/importance-of-accommodation-and-eye-dominance-for-measuring-objective-refractions
#8
LETTER
Andrzej Grzybowski, Ronald A Schachar, Barbara K Pierscionek, Norman S Levy, Ira H Schachar
No abstract text is available yet for this article.
April 12, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28392176/increased-frequency-of-topical-steroids-provides-benefit-in-patients-with-recalcitrant-postsurgical-macular-edema
#9
Peter A Campochiaro, Yong S Han, Tahreem A Mir, Saleema Kherani, Gulnar Hafiz, Claudia Krispel, T Y Alvin Liu, Jiangxia Wang, Adrienne W Scott, Ingrid Zimmer-Galler
PURPOSE: To compare standard and frequent topical steroids for postsurgical macular edema (ME) DESIGN: Randomized clinical trial METHODS: Subjects with postsurgical ME stratified into post-cataract surgery ME (PCSME) and post-other surgery ME (POSME) were randomized to ketorolac four times a day (qid) + 1% prednisolone acetate (PA) every hour while awake (q1hWA, group 1) or qid (group 2). Mean change from baseline best corrected visual acuity (BCVA) was determined at week 12 after which group 2 subjects with persistent edema were crossed over to PA q1hWA...
April 6, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28390651/corneal-endothelial-cell-density-in-children-normative-data-from-birth-to-5-years-old
#10
LETTER
Uri Elbaz, Kamiar Mireskandari, Nasrin Tehrani, Carl Shen, Muhammad Saad Khan, Sara Williams, Asim Ali
No abstract text is available yet for this article.
April 5, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28385474/geographic-atrophy-and-foveal-sparing-changes-related-to-visual-acuity-in-patients-with-dry-age-related-macular-degeneration-over-time
#11
Ramzi Gilbert Sayegh, Stefan Sacu, Roman Dunavölgyi, Maria Elisabeth Kroh, Philipp Roberts, Christoph Mitsch, Alessio Montuoro, Margit Ehrenmüller, Ursula Schmidt-Erfurth
PURPOSE: To correlate the area of geographic atrophy (GA) and residual foveal sparing (FS), and to identify the minimum FS and maximum GA area allowing sufficient visual acuity (VA) for daily tasks. DESIGN: Prospective cohort study METHODS: Thirty-six eyes of 25 patients with GA and FS were followed for 18 months using spectral-domain optical coherence tomography and VA tests. Volume scans were imported into software enabling grading of areas in B-scans and computing of planimetric measurements in complete volume scans...
April 3, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28385473/the-utility-of-repeat-culture-in-fungal-corneal-ulcer-management-a-secondary-analysis-of-the-mutt-i-randomized-clinical-trial
#12
Kathryn J Ray, Prajna Lalitha, N Venkatesh Prajna, Revathi Rajaraman, Tiruvengada Krishnan, Muthiah Srinivasan, Peter Ryg, Stephen McLeod, Nisha R Acharya, Thomas M Lietman, Jennifer Rose-Nussbaumer
PURPOSE: To determine whether patients who had a positive repeated culture was predictive of worse clinical outcome than those who achieved microbiological cure at 6 days in the Mycotic Ulcer Treatment Trial I (MUTT-I). DESIGN: Secondary analysis from a multicenter, double-masked, randomized clinical trial. METHODS: Setting: Multiple hospital sites of the Aravind Eye Care System, India. STUDY POPULATION: Patients with culture-positive filamentous fungal ulcers and visual acuity of 20/40 to 20/400 re-examined 6 days after initiation of treatment Intervention: Corneal scraping and cultures were obtained from study participants at day-6 after enrollment...
April 3, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28366648/randomized-control-trial-evaluating-a-standardized-strategy-for-uveitis-etiological-diagnosis-ulisse
#13
Audrey de Parisot, Laurent Kodjikian, Marie-Hélène Errera, Neila Sedira, Emmanuel Heron, Laurent Pérard, Pierre-Loïc Cornut, Christelle Schneider, Sophie Rivière, Priscille Ollé, Grégory Pugnet, Pascal Cathébras, Pierre Manoli, Bahram Bodaghi, David Saadoun, Stéphanie Baillif, Nathalie Tieulie, Marc Andre, Frédéric Chiambaretta, Nicolas Bonin, Philip Bielefeld, Alain Bron, Frédéric Mouriaux, Boris Bienvenu, Stéphanie Vicente, Sylvie Bin, Christiane Broussolle, Evelyne Decullier, Pascal Sève
PURPOSE: To prospectively assess the efficiency of a standardized diagnostic approach, compared to an open strategy, for the etiological diagnosis of uveitis. DESIGN: Non-inferiority, prospective, multicenter, clustered randomized control trial. METHODS: Consecutive patients with uveitis, who visited one of the participating Departments of Ophthalmology, were included. In the standardized group, all patients had a minimal work-up regardless of the type of uveitis (complete blood count, erythrocyte sedimentation rate, C-reactive protein, tuberculin skin test, syphilis serology and chest X ray) followed by more complex investigations according to ophthalmological findings...
March 30, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28366647/adjustable-bilateral-superior-oblique-tendon-advancement-for-bilateral-fourth-nerve-palsy
#14
Bashar M Bata, David A Leske, Jonathan M Holmes
PURPOSE: Bilateral fourth nerve palsy may be symmetric or asymmetric with combined vertical and excylotropic deviations and so there may be an advantage to independent adjustment of vertical and torsional components. We report a surgical technique that allows such independent adjustment. DESIGN: Retrospective interventional case series. METHODS: 15 patients, age 17 to 73 years, underwent adjustable bilateral superior oblique tendon advancements for bilateral fourth nerve palsy (11 symmetric (≤2 prism diopters [pd] hyperdeviation in straight ahead gaze) and 4 asymmetric)...
March 30, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28366429/the-growing-stem-cell-clinic-problem
#15
EDITORIAL
Ajay E Kuriyan, Thomas A Albini, Harry W Flynn
No abstract text is available yet for this article.
March 30, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28366428/in%C3%A2-vivo-porcine-model-of-venous-air-embolism-during-pars-plana-vitrectomy
#16
LETTER
Steven Gayer, Howard D Palte, Thomas A Albini, Harry W Flynn, Ricardo Martinez-Ruiz, Nelson Salas, Andrew J Mcclellan, Nidhi Relhan, Jean-Marie Parel
No abstract text is available yet for this article.
March 30, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28365241/adjuvant-ab-interno-tumor-treatment-after-proton-beam-irradiation
#17
Ira Seibel, Aline I Riechardt, Jens Heufelder, Dino Cordini, Antonia M Joussen
PURPOSE: This study was performed to show long-term outcomes concerning globe preservation in uveal melanoma patients after proton beam therapy with the main focus on outcomes according to different adjuvant ab interno surgical procedures. DESIGN: Retrospective cohort study METHODS: All patients treated with primary proton beam therapy for choroidal or ciliary body melanoma between June 1998 and June 2015 were included. RESULTS: A total of 2499 patients underwent primary proton beam therapy, with local tumor control and globe preservation rates of 95...
March 29, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28365240/using-electronic-health-records-to-build-an-ophthalmological-data-warehouse-and-visualize-patients-data
#18
Karsten U Kortüm, Michael Müller, Christoph Kern, Alexander Babenko, Wolfgang J Mayer, Anselm Kampik, Thomas C Kreutzer, Siegfried Priglinger, Christoph Hirneiss
PURPOSE: To develop a near real-time data warehouse (DW) in an academic ophthalmological center to gain scientific use of increasing digital data from electronic medical records (EMR) and diagnostic devices. Design; Database development METHODS: Specific macular clinic user interfaces within the institutional hospital information system were created. Orders for imaging modalities were sent by an EMR -linked picture-archiving and communications system to the respective devices. All data of 325,767 patients since 2002 were gathered in a DW running on a SQL database...
March 29, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28364947/same-site-trabeculectomy-revision-for-failed-trabeculectomy-outcomes-and-risk-factors-for-failure
#19
LETTER
Pradtana Hirunpatravong, Reza Alizadeh, Pablo Romero, Eun Ah Kim, Kouros Nouri-Mahdavi, Simon K Law, Esteban Morales, Joseph Caprioli
No abstract text is available yet for this article.
March 29, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28364946/relationships-between-anthropometric-measurements-and-intraocular-pressure-the-korea-national-health-and-nutrition-examination-survey
#20
LETTER
Brice Dille
No abstract text is available yet for this article.
March 29, 2017: American Journal of Ophthalmology
journal
journal
20017
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"