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American Journal of Ophthalmology

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https://www.readbyqxmd.com/read/28549849/optimizing-glaucoma-screening-in-high-risk-population-design-and-1-year-findings-of-the-screening-to-prevent-stop-glaucoma-study
#1
Di Zhao, Eliseo Guallar, Prateek Gajwani, Bonnielin Swenor, John Crews, Jinan Saaddine, Lucy Mudie, Varshini Varadaraj, David S Friedman
PURPOSE: To develop, implement, and evaluate replicable community-based screening intervention designed to improve glaucoma and other eye disease detection and follow-up care in high-risk populations in the United States. We present the design of the study and describe the findings of the first year of the program. DESIGN: Prospective study to evaluate screening and follow-up. METHODS: This is an ongoing study to develop an eye screening program using trained personnel to identify individuals with ophthalmic needs, focusing on African Americans ≥50 years of age at multiple inner-city community sites in Baltimore, MD...
May 23, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28549848/relationship-between-visual-acuity-and-retinal-thickness-during-anti-vascular-endothelial-growth-factor-therapy-for-retinal-diseases
#2
William C Ou, David M Brown, John F Payne, Charles C Wykoff
PURPOSE: Investigate the relationship between best-corrected visual acuity (BCVA) and central retinal thickness (CRT) in eyes receiving ranibizumab for three common retinal diseases. DESIGN: Retrospective analysis of clinical trial data METHODS: Early Treatment Diabetic Retinopathy Study BCVA and spectral-domain optical coherence tomography measured CRT of 387 eyes of 345 patients enrolled in six prospective clinical trials for management of neovascular age-related macular degeneration (AMD), diabetic macular edema (DME), and retinal vein occlusion (RVO) were evaluated by Pearson correlation and linear regression...
May 23, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28549847/trends-in-hospitalization-and-incidence-rate-for-syphilitic-uveitis-in-the-united-states-from-1998-2009
#3
Thomas Albini, Natalia F Callaway, Suzann Pershing, Sean K Wang, Andrew A Moshfeghi, Darius M Moshfeghi
PURPOSE: This study evaluates the annual incidence of syphilitic uveitis in the US and trends in hospital admissions over time. DESIGN: Retrospective, longitudinal incidence rate analysis of the National Inpatient Sample (NIS) data from 1998 to 2009. METHODS: The NIS is a de-identified, random sample dataset of inpatient hospitalizations from 46 states. The number of cases of syphilitic uveitis was defined: 1) ICD-9 code for syphilis and uveitis or 2) ICD-9 code for syphilitic uveitis...
May 23, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28549846/physical-activity-and-age-related-macular-degeneration-a-systematic-literature-review-and-meta-analysis
#4
Myra B McGuinness, Jerome Le, Paul Mitchell, Bamini Gopinath, Ester Cerin, Nicole T M Saksens, Tina Schick, Carel B Hoyng, Robyn H Guymer, Robert P Finger
PURPOSE: Age-related macular degeneration (AMD) is the main cause of irreversible severe vision loss in developed countries. It has been suggested that a healthy lifestyle may assist in delaying the onset and progression of AMD, however evidence for an association between physical activity and age-related macular degeneration (AMD) remains inconclusive. DESIGN: Systematic review and meta-analysis METHODS: Medline, EMBASE and Google Scholar were systematically searched for studies up to May 2015...
May 23, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28549845/tomographic-analysis-of-anterior-posterior-and-total-corneal-refractive-power-changes-after-femtosecond-laser-assisted-keratotomy
#5
Franziska Löffler, Myriam Böhm, Michael Herzog, Kerstin Petermann, Thomas Kohnen
PURPOSE: To analyze the effect of penetrating femtosecond laser-assisted keratotomy (pFLAK) during laser lens surgery on anterior, posterior corneal astigmatism and total corneal refractive power (TCRP) astigmatism (CAant, CApost, CATCRP) measured with Scheimpflug tomography. DESIGN: Prospective, interventional case series. METHODS: This institutional study included 27 eyes of 23 patients (65 ± 8 years) with low to moderate CATCRP determined with Scheimpflug tomography (Pentacam HR) after penetrating femtosecond laser-assisted keratotomy (pFLAK) and laser lens surgery...
May 23, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28528121/determinants-of-ocular-pain-severity-in-patients-with-dry-eye-disease
#6
Vannarut Satitpitakul, Ahmad Kheirkhah, Alja Crnej, Pedram Hamrah, Reza Dana
PURPOSE: To quantify the severity of ocular pain in patients with dry eye disease (DED) and evaluate factors associated with pain severity. DESIGN: Cross-sectional study. METHODS: Eighty-four patients with DED were asked to score their severity level of ocular pain using a 10-point scale, with 10 indicating the most severe pain. All patients also had a comprehensive ophthalmic assessment including a detailed history, Ocular Surface Disease Index (OSDI) questionnaire, and ocular surface examination...
May 17, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28528120/objective-evaluation-of-corneal-and-lens-clarity-in-children-with-type-1-diabetes-mellitus
#7
Kemal Tekin, Merve Inanc, Erdal Kurnaz, Elvan Bayramoglu, Emre Aydemir, Mustafa Koc, Zehra Aycan
PURPOSE: To investigate whether abnormal glucose metabolism and duration of diabetes mellitus (DM) affected the corneal and lens clarity in children with well-controlled Type 1 DM and to compare the results obtained with those in healthy children. DESIGN: Cross-sectional prospective study. METHODS: This multicenter study enrolled 56 patients with DM and 51 control subjects. The duration of DM and the glycosylated hemoglobin (HbA1c) levels of the patients in the DM group were recorded...
May 17, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28528085/inferior-rectus-transposition-a-novel-procedure-for-abducens-palsy
#8
LETTER
Emin Cumhur Sener, Pinar Topcu Yilmaz
No abstract text is available yet for this article.
May 17, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28528084/inferior-rectus-transposition-a-novel-procedure-for-abducens-palsy
#9
LETTER
Federico G Velez, Melinda Y Chang, Stacy L Pineles
No abstract text is available yet for this article.
May 17, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28528083/randomized-controlled-trial-evaluating-a-standardized-strategy-for-uveitis-etiologic-diagnosis-ulisse
#10
LETTER
Audrey de Parisot, Yvan Jamilloux, Laurent Kodjikian, Marie-Hélène Errera, Neila Sedira, Emmanuel Heron, Laurent Pérard, Pierre-Loïc Cornut, Christelle Schneider, Sophie Rivière, Priscille Ollé, Grégory Pugnet, Pascal Cathébras, Pierre Manoli, Bahram Bodaghi, David Saadoun, Stéphanie Baillif, Nathalie Tieulie, Marc Andre, Frédéric Chiambaretta, Nicolas Bonin, Philip Bielefeld, Alain Bron, Frédéric Mouriaux, Boris Bienvenu, Stéphanie Vicente, Sylvie Bin, Christiane Broussolle, Evelyne Decullier, Pascal Sève
No abstract text is available yet for this article.
May 17, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28526552/anisometropia-at-age-5-years-after-unilateral-intraocular-lens-implantation-during-infancy-in-the-infant-aphakia-treatment-study-iats
#11
David Weakley, George Cotsonis, M Edward Wilson, David A Plager, Edward G Buckley, Scott R Lambert
PURPOSE: To report the prevalence of anisometropia at age 5 years after unilateral intraocular lens (IOL) implantation in infants. DESIGN: Prospective randomized clinical trial METHODS: Fifty-seven infants in the Infant Aphakia Treatment Study (IATS) with a unilateral cataract were randomized to IOL implantation with an initial targeted postoperative refractive error of either +8D (infants 28 to <48 days of age) or +6D (infants 48-210 days of age). Anisometropia was calculated at age 5 years...
May 16, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28522028/prevalence-of-antiretinal-antibodies-in-acute-zonal-occult-outer-retinopathy-a-comprehensive-review-of-25-cases
#12
LETTER
Farzin Forooghian
No abstract text is available yet for this article.
May 15, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28522027/randomized-controlled-trial-evaluating-a-standardized-strategy-for-uveitis-etiologic-diagnosis-ulisse
#13
LETTER
Christopher T Leffler, Vikram S Brar, Michael Wallace
No abstract text is available yet for this article.
May 15, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28501392/acute-retinal-necrosis-presenting-characteristics-and-clinical-outcomes-in-a-cohort-of-polymerase-chain-reaction-positive-patients
#14
Nicholas J Butler, Ahmadreza Moradi, Sherveen S Salek, Bryn M Burkholder, Theresa G Leung, James P Dunn, Jennifer E Thorne
PURPOSE: To identify determinants of adverse outcomes in acute retinal necrosis (ARN), presenting characteristics and incidence rates of vision loss and ocular complications in a cohort of polymerase chain reaction (PCR)-positive eyes were analyzed. DESIGN: Retrospective, observational cohort study. METHODS: Forty-one eyes of 36 patients with clinically-diagnosed ARN, PCR-positive for herpes simplex virus or varicella zoster virus and evaluated between January 2002 and June 2013, were included...
May 10, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28501391/long-term-visual-acuity-strabismus-and-nystagmus-outcomes-following-multimodality-treatment-in-group-d-retinoblastoma-eyes
#15
Ido D Fabian, Zishan Naeem, Andrew W Stacey, Tanzina Chowdhury, Catriona Duncan, M Ashwin Reddy, Mandeep S Sagoo
PURPOSE: To analyse the long-term visual acuity, strabismus and nystagmus outcomes in Group D retinoblastoma following multimodality treatments in a national retinoblastoma referral centre. DESIGN: Retrospective interventional case series. METHODS: A 13-year retrospective chart review of Group D eyes treated initially with intravenous chemotherapy (IVC) and followed-up for at least 1 year from last treatment. Risk factors for final visual acuity (VA) were analysed, and rate of strabismus and nystagmus at last follow-up visit were calculated...
May 10, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28501390/clinical-features-and-incidence-rates-of-ocular-complications-in-patients-with-retinal-vasculitis
#16
Tahreem A Mir, Ashvini K Reddy, Bryn M Burkholder, James Walsh, Amde Selassie Shifera, Irfan R Khan, Jennifer E Thorne
PURPOSE: To describe the incidence rates of visual loss and ocular complications in patients with retinal vasculitis (RV). DESIGN: Retrospective cohort study METHODS: Clinical data were collected for 96 patients (175 eyes) diagnosed with RV from 2003 to 2013. Main outcome measures included rates of visual loss and ocular complications. Comparison of outcomes in patients with a relapsing versus non-relapsing disease also were analyzed. RESULTS: Over a median follow-up of 44 months (range: 1-153), the rate of visual loss to 20/50 or worse was 0...
May 10, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28499706/pseudophakic-macular-edema-in-primary-open-angle-glaucoma-a-prospective-study-using-spectral-domain-optical-coherence-tomography
#17
Kyoung Min Lee, Eun Ji Lee, Tae-Woo Kim, Hyunjoong Kim
PURPOSE: To determine the incidence of and risk factors for pseudophakic macular edema (PME) after uncomplicated cataract surgery in primary open-angle glaucoma (POAG) using spectral-domain optical coherence tomography (SD-OCT). DESIGN: Cohort study METHODS: Macular retinal thickness was evaluated using SD-OCT at 1-week before surgery and at 1-, 3-, 6-, and 12-months postoperatively, in 70 POAG and 68 control eyes. Forty-three healthy subjects without impaired vision or cystoid PME were recruited separately as pilot samples to define significant PME...
May 10, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28499708/incidence-of-intermediate-stage-age-related-macular-degeneration-in-patients-with-the-acquired-immunodeficiency-syndrome
#18
Douglas A Jabs, Mark L Van Natta, Jeong Won Pak, Ronald P Danis, Peter W Hunt
PURPOSE: To evaluate the incidence of intermediate-stage age-related macular degeneration (AMD) in patients with the acquired immunodeficiency syndrome (AIDS). DESIGN: Cohort study. METHODS: Patients enrolled in the Longitudinal Study of the Ocular Complications of AIDS (LSOCA) underwent 5- and 10-year follow-up retinal photographs. Intermediate-stage AMD (AREDS stage 3) was determined from these photographs by graders at a centralized Reading Center, using the Age-Related Eye Disease Study-2 grading system...
May 9, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28499707/lower-laser-energy-levels-lead-to-better-visual-recovery-after-small-incision-lenticule-extraction-prospective-randomized-clinical-trial
#19
Yong Woo Ji, Minseo Kim, David Sung Yong Kang, Dan Reinstein, Timothy Archer, Jin Young Choi, Eung Kweon Kim, Hyung Keun Lee, Kyoung Yul Seo, Tae-Im Kim
PURPOSE: To determine the effect of lowering laser energy on clinical outcomes in small-incision lenticule extraction (SMILE). DESIGN: Prospective, randomized clinical trial. METHODS: 151 patients (151 eyes) with moderate myopia scheduled for SMILE were included: 58 eyes received SMILE with low energy (100, 105, and 110 nJ; L-SMILE group) and 93 with conventional energy (115 to 150 nJ; C-SMILE group). Patients received complete ophthalmic examinations preoperatively and over 3 months postoperatively...
May 9, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28499705/measurement-and-reproducibility-of-preserved-ellipsoid-zone-area-and-preserved-rpe-area-in-a-cohort-of-eyes-with-choroideremia
#20
Amir H Hariri, Swetha B Velaga, Aniz Girach, Michael S Ip, Phuc V Le, Byron L Lam, M Dominik Fischer, Eeva-Marja Sankila, Mark Pennesi, Frank G Holz, Robert E MacLaren, David G Birch, Carel B Hoyng, Ian M MacDonald, Graeme C Black, Stephen H Tsang, Neil M Bressler, Michael Larsen, Michael B Gorin, Andrew R Webster, SriniVas R Sadda
PURPOSE: To identify valid and reproducible methods for quantifying anatomical outcome measures for eyes with choroideremia (CHM) in clinical trials. DESIGN: Reliability analysis study. METHODS: In this multicenter study, patients with confirmed genetic diagnosis of CHM were enrolled. All cases underwent spectral domain optical coherence tomography (SD-OCT) and fundus autofluorescence (FAF) imaging. Two graders independently delineated boundaries of preserved autofluorescence (PAF) and preserved ellipsoid zone (EZ) on FAF and OCT images respectively...
May 9, 2017: American Journal of Ophthalmology
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