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American Journal of Ophthalmology

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https://www.readbyqxmd.com/read/29038011/macular-fluid-reduces-reproducibility-of-choroidal-thickness-measurements-on-enhanced-depth-optical-coherence-tomography
#1
Sophia S Wong, Vivian S Vuong, David Cunefare, Sina Farsiu, Ala Moshiri, Glenn Yiu
PURPOSE: To determine if different types of retinal fluid in the central macula affect the reproducibility of choroidal thickness (CT) measurements on enhanced depth imaging optical coherence tomography (EDI-OCT) DESIGN: retrospective, reliability analysis METHODS: EDI-OCT images were obtained and the choroidal-scleral junction was analyzed through semi-automated segmentation. CT was measured at the fovea and averaged across the central 3 mm horizontal segment. Demographic data, central macular thickness and type of fluid present were recorded...
October 13, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29038010/peripheral-visual-fields-in-abca4-stargardt-disease-and-correlation-with-disease-extent-on-ultra-widefield-fundus-autofluorescence
#2
Maria Fernanda Abalem, Benjamin Otte, Chris Andrew, Katherine A Joltikov, Kari Branham, Abigail T Fahim, Dana Schlegel, Cynthia X Qian, John R Heckenlively, Thiran Jayasundera
PURPOSE: To evaluate the disease extent on ultra-widefield fundus autofluorescence (UWF-FAF) in patients with ABCA4- Stargardt disease (STGD) and correlate this data with functional outcome measures. DESIGN: Retrospective cross sectional study SETTING: Kellogg Eye Center, University of Michigan STUDY POPULATION: Sixty-five patients with clinical diagnosis and proven pathogenic variants in the ABCA4 gene. OBSERVATIONAL PROCEDURES: The UWF-FAF images were obtained using Optos 200- degrees and classified into three types...
October 13, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29032939/disorganization-of-the-retinal-inner-layers-as-a-predictor-of-visual-acuity-in-eyes-with-macular-edema-secondary-to-vein-occlusion
#3
LETTER
Michael Mimouni, Dalia Dori, Victor Flores, Or Segev, Noa Geffen, Ori Segal
No abstract text is available yet for this article.
October 12, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29032110/use-of-donors-predisposed-by-corneal-collagen-cross-linking-in-penetrating-keratoplasty-for-treating-the-patients-with-keratoconus
#4
Ting Huang, Ruifen Ye, Chen Ouyang, Chao Hou, Yunwei Hu, Qianni Wu
PURPOSE: To investigate whether use of donors predisposed by corneal collagen cross-linking (CXL) reduced myopic refractive errors for keratoconic eyes after penetrating keratoplasty (PK). DESIGN: Randomized controlled trial. METHODS: One hundred sixteen eyes of 116 patients with keratoconus from Zhongshan Ophthalmic Center were enrolled. Using stratified block randomization, eligible eyes were assigned to CXL graft group (Group1) or conventional graft group (Group2)...
October 12, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29032109/early-response-to-intravitreal-dexamethasone-implant-therapy-in-diabetic-macular-edema-may-predict-visual-outcome
#5
Hasenin Al-Khersan, Seenu M Hariprasad, Jay Chhablani
PURPOSE: To determine whether early visual acuity response to intravitreal dexamethasone implant therapy in diabetic macular edema (DME) is associated with long-term outcome. DESIGN: Retrospective case series METHODS: Multicenter (eight sites) retrospective review of medical records of eyes with DME treated with 0.7mg intravitreal dexamethasone implant and minimum eighteen-month follow-up. One hundred and two eyes were included. Eyes with vitroretinal interface abnormalities or that had undergone vitrectomy were excluded...
October 12, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29032108/pregnancy-induced-changes-in-corneal-biomechanics-and-topography-are-thyroid-hormone-related
#6
David Tabibian, Begoña M de Tejada, Zisis Gatzioufas, Sabine Kling, Vanessa S Meiss, Marc-Olivier Boldi, Véronique Othenin-Girard, Antonina Chilin, Julien Lambiel, Florence Hoogewoud, Farhad Hafezi
PURPOSE: To identify biomechanical and topographical changes of the cornea during pregnancy and the postpartum period and its association to hormonal changes. DESIGN: Prospective single-center observational cohort study. METHODS: Participants: 24 pregnant women (48 eyes), monitored throughout pregnancy and after delivery. Biomechanical and topographical corneal properties were measured using the Ocular Response Analyzer (ORA) and a Scheimpflug imaging system (Pentacam HR) each trimester and 1 month after delivery...
October 12, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29032107/long-term-outcomes-of-ocular-surface-stem-cell-allograft-transplantation
#7
Asadolah Movahedan, Albert Y Cheung, Medi Eslani, Gautham Mogilishetty, Amit Govil, Edward J Holland
PURPOSE: To investigate the long-term outcomes of ocular surface stem cell allograft transplantation (OSST) in patients with total limbal stem cell deficiency (LSCD) due to various etiologies with a follow-up ≥ 5 years. DESIGN: Retrospective interventional cohort. METHODS: ▪▪▪ SETTING: Single tertiary referral hospital. STUDY POPULATION: Patients who had (1) presence of total LSCD, (2) surgical treatment with at least one allograft OSST procedure, and (3) minimum follow-up ≥ 5 years after OSST...
October 12, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29025681/physician-assistants-and-nurse-practitioners-in-ophthalmology-has-the-time-come
#8
EDITORIAL
David J Browning
No abstract text is available yet for this article.
October 9, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29025680/disorganization-of-the-retinal-inner-layers-as-a-predictor-of-visual-acuity-in-eyes-with-macular-edema-secondary-to-vein-occlusion
#9
LETTER
Dan Călugăru, Mihai Călugăru
No abstract text is available yet for this article.
October 9, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28988899/diabetic-choroidopathy-choroidal-vascular-density-and-volume-in-diabetic-retinopathy-with-swept-source-optical-coherence-tomography
#10
Jay C Wang, Inês Laíns, Joana Providência, Grayson W Armstrong, Ana R Santos, Pedro Gil, João Gil, Katherine E Talcott, João H Marques, João Figueira, Demetrios G Vavvas, Ivana K Kim, Joan W Miller, Deeba Husain, Rufino Silva, John B Miller
PURPOSE: To compare choroidal vascular density (CVD) and volume (CVV) in diabetic eyes and controls, using en face swept-source optical coherence tomography (SS-OCT). DESIGN: Prospective cross-sectional study. METHODS: ▪▪▪ SETTING: Multicenter PATIENT POPULATION: 143 diabetic eyes - 27 with no diabetic retinopathy (DR), 47 with nonproliferative DR (NPDR), 51 with NPDR and diabetic macular edema (DME), and 18 with proliferative DR (PDR), and 64 age-matched non-diabetic control eyes...
October 5, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28988898/elevated-aqueous-cytokine-levels-in-eyes-with-ocular-surface-diseases
#11
Naohiko Aketa, Takefumi Yamaguchi, Teru Asato, Yukari Yagi-Yaguchi, Terumasa Suzuki, Kazunari Higa, Toshihide Kurihara, Yoshiyuki Satake, Kazuo Tsubota, Jun Shimazaki
PURPOSE: To evaluate cytokine and protein levels in the aqueous humor (AqH) of eyes with ocular surface diseases. DESIGN: Prospective consecutive case series. METHODS: This study includes 14 patients (62.4±13.7 years old) with chronic-phase ocular surface diseases (4 with ocular cicatricial pemphigoid, 5 with chemical burns, 2 with a thermal burn, 2 with Stevens-Johnson syndrome, and 1 with exposure keratitis), 14 matched patients without ocular surface disease (controls with corneal scar) and 30 patients who underwent cataract surgery (healthy controls)...
October 5, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28988897/outcomes-and-prognostic-factors-of-cataract-surgery-in-adult-extreme-microphthalmos-with-axial-length-18-mm-or-corneal-diameter-8-mm
#12
Tianyu Zheng, Zhanghua Chen, Jie Xu, Yating Tang, Qi Fan, Yi Lu
PURPOSE: To study the long-term visual outcomes, complications and prognostic factors for cataract surgery in extreme microphthalmos. DESIGN: Prospective cohort study. METHODS: Thirty eyes with simple microphthalmos [11 eyes, axial length (AL) <18 mm], complex microphthalmos [8 eyes, AL <18 mm] and relative anterior microphthalmos [RAM, 11 eyes, corneal diameter (CD) <8 mm] who underwent cataract surgery (phacoemulsification) in our hospital were followed for a mean of 25...
October 5, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28964806/comparison-of-glaucoma-progression-detection-by-optical-coherence-tomography-and-visual-field
#13
Xinbo Zhang, Anna Dastiridou, Brian A Francis, Ou Tan, Rohit Varma, David S Greenfield, Joel S Schuman, David Huang
PURPOSE: To compare longitudinal glaucoma progression detection using optical coherence tomography (OCT) and visual field (VF). DESIGN: Validity assessment METHOD: We analyzed subjects with more than 5 follow-up visits (every 6 months) in the multi-center Advanced Imaging for Glaucoma Study. Fourier-domain optical coherence tomography (OCT) was used to map the thickness of the peripapillary retinal nerve fiber layer (NFL) and ganglion cell complex (GCC). OCT-based progression detection was defined as a significant negative trend for either NFL or GCC...
September 27, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28964805/optical-coherence-tomography-protocols-for-screening-of-hydroxychloroquine-retinopathy-in-asian-patients
#14
Seong Joon Ahn, Jooyoung Joung, Han Woong Lim, Byung Ro Lee
PURPOSE: To investigate the distribution of outer retinal changes in hydroxychloroquine (HCQ) retinopathy and explore optical coherence tomography (OCT) protocols to maximize the sensitivity of HCQ retinopathy detection in Asian patients. DESIGN: Diagnostic validity assessment METHODS: Setting: Institutional Patient Population: Forty-eight eyes (24 patients) with HCQ retinopathy underwent 6-mm horizontal and vertical line scans and 6 × 6-mm(2) volume scans using spectral-domain OCT (SD-OCT), and 9-mm line scans and 6 × 6-mm(2) and 12 × 9-mm(2) volume scans using swept-source OCT (SS-OCT)...
September 27, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28964804/differences-in-oct-assessment-of-bruch-membrane-opening-compared-to-stereoscopic-photography-for-estimating-cup-to-disc-ratio
#15
Jean-Claude Mwanza, Linda Y Huang, Donald L Budenz, Wei Shi, Gintien Huang, Richard K Lee
PURPOSE: To compare the vertical and horizontal cup-to-disc ratio (VCDR, HCDR) by an updated optical coherence tomography (OCT) Bruch's membrane opening (BMO) algorithm and stereoscopic optic disc photograph readings by glaucoma specialists. DESIGN: Reliability analysis. METHODS: 195 eyes (116 glaucoma and 79 glaucoma suspects) of 99 patients with stereoscopic photos and OCT scans of the optic discs taken during the same visit were compared...
September 27, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28962966/west-indies-glaucoma-laser-study-wigls-1-12-month-efficacy-of-selective-laser-trabeculoplasty-in-afro-caribbeans-with-glaucoma
#16
Tony Realini, Hazel Shillingford-Ricketts, Darra Burt, Goundappa K Balasubramani
PURPOSE: To characterize the 12-month intraocular pressure (IOP)-lowering efficacy of selective laser trabeculoplasty (SLT) as sole therapy for primary open-angle glaucoma (POAG) in an Afro-Caribbean population. DESIGN: Stepped-wedge trial. METHODS: Subjects in St. Lucia and Dominica with established POAG were randomized to prompt washout of IOP-lowering medications followed by SLT, 3-month delay followed by washout and SLT, or 6-month delay followed by washout and SLT...
September 26, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28947074/the-isnt-rule-how-often-does-it-apply-to-disc-photos-and-retinal-nerve-fiber-layer-measurements-in-the-normal-population
#17
Linda Yi-Chieh Poon, David Solá-Del Valle, Angela V Turalba, Iryna A Falkenstein, Michael Horsley, Julie H Kim, Brian J Song, Hana L Takusagawa, Kaidi Wang, Teresa C Chen
PURPOSE: To determine what percentage of normal eyes follow the ISNT rule, and whether ISNT rule variants may be more generalizable to the normal population. DESIGN: Cross-sectional study. METHODS: Setting: Institutional setting. STUDY POPULATION: 110 normal subjects. OBSERVATION PROCEDURES: Neuroretinal rim assessments from disc photos and RNFL thickness measurements from spectral domain OCT. MAIN OUTCOME MEASURES: The percentages of subjects that obeyed the ISNT rule and its variants...
September 22, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28947061/outcomes-in-autoimmune-retinopathy-patients-treated-with-rituximab
#18
LETTER
Samaneh Davoudi, Nazanin Ebrahimiadib, Cagla Yasa, Damla D Sevgi, Ramak Roohipoor, Evangelia Papavasilieou, Jason Comander, Lucia Sobrin
No abstract text is available yet for this article.
September 22, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28943388/corneal-higher-order-aberrations-and-visual-improvement-following-corneal-transplantation-in-treating-herpes-simplex-keratitis
#19
Eisuke Shimizu, Takefumi Yamaguchi, Daisuke Tomida, Yukari Yagi-Yaguchi, Yoshiyuki Satake, Kazuo Tsubota, Jun Shimazaki
PURPOSE: To examine corneal higher-order aberrations (HOAs) and visual improvement following corneal transplantation in treating corneal scar caused by herpes simplex keratitis (HSK). DESIGN: Retrospective consecutive case series. METHODS: This study included a total of 52 eyes: 18 normal subjects, and 34 eyes of consecutive patients with corneal scar due to HSK who underwent penetrating keratoplasty (PKP, 17 eyes) or deep anterior lamellar keratoplasty (DALK, 17 eyes)...
September 21, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28942895/increased-frequency-of-topical-steroids-provides-benefits-in-patients-with-recalcitrant-postsurgical-postsurgical-macular-edema
#20
LETTER
Punita Kumari Sodhi
No abstract text is available yet for this article.
September 21, 2017: American Journal of Ophthalmology
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