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American Journal of Ophthalmology

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https://www.readbyqxmd.com/read/29655645/proton-beam-irradiation-a-safe-procedure-in-post-equatorial-extraocular-extension-from-uveal-melanoma
#1
Ira Seibel, Aline I Riechardt, Katharina Erb-Eigner, Alexander Böker, Dino Cordini, Jens Heufelder, Antonia M Joussen
PURPOSE: This study was performed to show long-term outcomes concerning metastasis rates and local recurrence rates after primary proton beam therapy in uveal melanoma with posterior extraocular extension (EOE) with the main focus on optic nerve invasion. DESIGN: Retrospective case series METHODS: All patients treated with primary proton beam therapy for choroidal or ciliary body melanoma with posterior EOE between July 1998 and August 2010 were included. EOE was either detected upon sonography at primary examination or during the surgical application of tantalum clips onto the sclera...
April 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29655644/long-term-changes-in-anterior-segment-characteristics-of-eyes-with-different-primary-angle-closure-mechanisms
#2
Junki Kwon, Kyung Rim Sung, Seungbong Han
PURPOSE: To assess long-term changes in the anterior segment (AS) of eyes with different angle closure mechanisms. DESIGN: Retrospective cohort study. METHODS: In total, 133 eyes (from 75 participants) with angle closure were enrolled. All eyes received laser iridotomy (LI) during the follow-up period. Serial anterior segment optical coherence tomography (AS-OCT) imaging was performed during a mean follow-up of 4 years. Participants were categorized into four groups according to angle closure mechanisms, based on baseline AS-OCT images: pupillary block (PB), plateau iris configuration (PIC), thick peripheral iris roll (TPIR), and exaggerated lens vault (ELV)...
April 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29655643/automated-segmentation-of-lesions-including-subretinal-hyperreflective-material-in-neovascular-age-related-macular-degeneration
#3
Hyungwoo Lee, Kyung Eun Kang, Hyewon Chung, Hyung Chan Kim
PURPOSE: To evaluate an automated segmentation algorithm with a convolutional neural network (CNN) to quantify and detect intraretinal fluid (IRF), subretinal fluid (SRF), pigment epithelial detachment (PED), and subretinal hyperreflective material (SHRM) through analyses of spectral domain optical coherence tomography (SD-OCT) images from patients with neovascular age-related macular degeneration (nAMD). DESIGN: Reliability and validity analysis of a diagnostic tool...
April 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29655642/estimating-medicare-and-patient-savings-from-the-use-of-bevacizumab-for-the-treatment-of-exudative-age-related-macular-degeneration
#4
Philip J Rosenfeld, Matthew A Windsor, William J Feuer, Sissi J J Sun, Kevin D Frick, Eric A Swanson, David Huang
PURPOSE: The Medicare cost savings from the use of bevacizumab in the United States for the treatment of exudative age-related macular degeneration (AMD) were estimated by replacing the use of bevacizumab with ranibizumab and aflibercept. DESIGN: Retrospective trend study. METHODS: Main outcome measures were spending by Medicare as tracked by Current Procedural Terminology (CPT) codes for intravitreal injections (67028) and treatment-specific J-codes (J0178, J2778, J9035, J3490 and J3590) for inhibitors of vascular endothelial growth factor...
April 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29655641/is-newer-necessarily-better-the-evolution-of-incisional-glaucoma-surgery-over-the-last-100-years
#5
Eve J Higginbotham, Dominique Alexis
PURPOSE: To examine the progress made in glaucoma incisional surgery and determine if there has been sufficient progress to meet the needs of glaucoma patients. DESIGN: Perspective: Literature Review METHODS: This is a retrospective assessment of key milestones in the evolution of glaucoma incisional surgery and an evaluation of the risks and the benefits of these procedures. Benefits are defined as effective reduction in intraocular pressure (IOP) and protecting visual function, while risks are defined as safety and complications for our patients...
April 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29655640/how-are-ocular-signs-and-symptoms-of-dry-eye-associated-with-depression-in-women-with-and-without-sj%C3%A3-gren-s-syndrome
#6
John A Gonzales, Annie Chou, Jennifer R Rose-Nussbaumer, Vatinee Y Bunya, Lindsey A Criswell, Caroline H Shiboski, Thomas M Lietman
PURPOSE: To determine whether ocular phenotypic features of keratoconjunctivitis sicca (KCS) and/or participant-reported symptoms of dry eye disease are associated with depression in women participants enrolled in the Sjögren's International Collaborative Clinical Alliance (SICCA). DESIGN: Cross-sectional study. METHODS: Women enrolled in the SICCA registry from 9 international research sites. Participants met at least one of five inclusion criteria for registry enrollment (including complaints of dry eyes or dry mouth, a previous diagnosis of Sjögren's syndrome (SS), abnormal serology (positive anti-Sjögren's syndrome-related antigen A and/or B (anti-SSA and/or anti-SSB), or elevated anti-nuclear antibody and rheumatoid factor), bilateral parotid gland enlargement, or multiple dental caries)...
April 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29655518/the-americanjournal-ofophthalmology-will-publish-american-ophthalmological-society-theses
#7
EDITORIAL
Richard K Parrish, Emily Chew, Hans E Grossniklaus
No abstract text is available yet for this article.
April 11, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29654738/genetic-and-phenotypic-traits-of-s-epidermidis-strains-causing-post-cataract-endophthalmitis-compared-to-commensal-conjunctival-flora
#8
Christophe Chiquet, Cécile Musson, Florent Aptel, Sandrine Boisset Pharm, Max Maurin
PURPOSE: The aim of this study was to compare the virulence and antibiotic resistance traits of Staphylococcus epidermidis strains causing acute post-cataract endophthalmitis to those isolated from the conjunctiva of uninfected control patients. DESIGN: Case-control study. METHODS: We isolated a S. epidermidis strain from each of the 22 endophthalmitis patients, and from 43 of the 72 controls. Species identification was confirmed using both Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry and tuf gene amplification and sequencing...
April 11, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29650227/long-term-progression-of-type-1-neovascularization-in-age-related-macular-degeneration-using-optical-coherence-tomography-angiography
#9
LETTER
David Xu, Juan Pablo Dávila, Mansour Rahimi, Carl B Rebhun, A Yasin Alibhai, Nadia K Waheed, David Sarraf
No abstract text is available yet for this article.
April 9, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29649424/the-safety-and-efficacy-of-supraciliary-stenting-following-failed-glaucoma-surgery
#10
Nathan M Kerr, Jing Wang, Lucia Perucho, Keith Barton
PURPOSE: To evaluate the safety and efficacy of supraciliary stenting following failed glaucoma surgery. DESIGN: Interventional case series. METHODS: Setting: Moorfields Eye Hospital, London, United Kingdom. STUDY POPULATION: Twenty eyes from 20 patients with glaucoma refractory to prior glaucoma surgery. INTERVENTION: Ab interno microstent (CyPass Micro-Stent; Alcon, Fort Worth, TX) implantation into the supraciliary space...
April 9, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29628114/measurement-and-associations-of-the-optic-nerve-subarachnoid-space-in-normal-tension-glaucoma-and-primary-open-angle-glaucoma
#11
LETTER
David Fleischman, Hanspeter Esriel Killer
No abstract text is available yet for this article.
April 5, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29627064/evaluating-the-usefulness-of-mp-3-microperimetry-in-glaucoma-patients
#12
LETTER
Masato Matsuura, Hiroshi Murata, Yuri Fujino, Kazunori Hirasawa, Mieko Yanagisawa, Ryo Asaoka
No abstract text is available yet for this article.
April 4, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29625699/measurement-and-associations-of-the-optic-nerve-subarachnoid-space-in-normal-tension-glaucoma-and-primary-open-angle-glaucoma
#13
LETTER
Hanruo Liu, Diya Yang, Teng Ma, Wenyuan Shi, Qiang Zhu, Jun Kang, Ningli Wang
No abstract text is available yet for this article.
April 3, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29625698/evaluating-the-usefulness-of-mp-3-microperimetry-in-glaucoma-patients
#14
LETTER
Marta Beatriz Rodríguez-Cavas, Miguel Tudela-Molino, Monica Del-Rio-Vellosillo, María Paz Villegas-Pérez, José Javier García-Medina
No abstract text is available yet for this article.
April 3, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29621512/evolution-of-outcomes-of-consecutive-dmek-surgeries-throughout-a-5-year-period-at-a-single-center-performed-by-two-experienced-dmek-surgeons
#15
Silvia Schrittenlocher, Friederike Schaub, Deniz Hos, Sebastian Siebelmann, Claus Cursiefen, Björn Bachmann
PURPOSE: To assess the evolution of clinical outcomes of more than 1300 DMEKs alone or in combination with cataract surgery (triple-DMEK) throughout a 5-year period at a single center performed by two already experienced DMEK surgeons. DESIGN: Retrospective trend study. METHODS: Review of charts between July 2011 and July 2016 at the Department of Ophthalmology, University of Cologne, Germany. RESULTS: 1340 out of 1340 eyes with sufficient information were included...
April 2, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29621511/spectral-domain-optical-coherence-tomography-in-limbal-stem-cell-deficiency-a-case-control-study
#16
Nilly Banayan, Cristina Georgeon, Kate Grieve, Vincent M Borderie
PURPOSE: To evaluate the efficacy of optical coherence tomography as a non-contact method for imaging the ocular surface in limbal stem cell deficiency (LSCD) and normal eyes. DESIGN: Retrospective case-control study. METHODS: SETTING: Institutional. STUDY POPULATION: 22 eyes with LSCD (study group, 22 patients) and 10 normal eyes (control group, 10 patients). OBSERVATION PROCEDURES: SD-OCT and confocal microscopy in both the limbal and central corneal zones...
April 2, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29621510/peripheral-changes-associated-with-delayed-dark-adaptation-in-age-related-macular-degeneration
#17
Inês Laíns, Dong Ho Park, Ryo Mukai, Rebecca Silverman, Patrick Oellers, Steven Mach, Ivana K Kim, Demetrios G Vavvas, Joan W Miller, John B Miller, Deeba Husain
PURPOSE: To study the association between peripheral changes in Age-related Macular Degeneration (AMD) and dark adaptation (DA). DESIGN: Prospective, cross-sectional study. METHODS: We recruited patients with AMD and a control group (> 50 years) without any vitreoretinal disease. Ultra-widefield (UWF) pseudocolor and fundus autofluorescence (FAF) (Optos Inc, MA) were obtained, and were assessed by two graders for the presence of several peripheral changes in perimacular, mid- and far-peripheral zones...
April 2, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29621509/long-term-choroidal-thickness-changes-in-eyes-with-drusenoid-pigment-epithelium-detachment
#18
Rosa Dolz-Marco, Chandrakumar Balaratnasingam, Sarra Gattoussi, Seungjun Ahn, Lawrence A Yannuzzi, K Bailey Freund
PURPOSE: To analyze the changes in visual acuity and subfoveal choroidal thickness in patients with non-neovascular age-related macular degeneration (AMD) and drusenoid pigment epithelium detachments (PED). DESIGN: Consecutive observational case series. METHODS: Observational retrospective review of eyes diagnosed with drusenoid PED in a single clinical setting. Demographic and clinical data included age, gender, laterality, best corrected visual acuity (BCVA) and subfoveal choroidal thickness measured at baseline, before and after the collapse of the PED, and at the last available follow-up...
April 2, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29621508/angiopoietin-like-3-is-a-potential-biomarker-for-retinopathy-in-type-2-diabetic-patients
#19
Cai-Guo Yu, Sha-Sha Yuan, Long-Yan Yang, Jing Ke, Li-Jie Zhang, Jia-Nan Lang, Da-Wei Zhang, Shao-Zhen Zhao, Dong Zhao, Ying-Mei Feng
PURPOSE: To investigate whether angiopoietin-like 3 (ANGPTL3) and angiopoietin-like 4 (ANGPTL4) are differentially associated with the severity of retinopathy in patients with type 2 diabetes mellitus (T2DM). DESIGN: Cross-sectional study. METHODS: Serum levels of ANGPTL3, ANGPTL4, high-sensitivity C-reactive protein (CRP), vascular adhesion molecule-1 (VCAM-1), intracellular adhesion molecule-1 (ICAM-1) and vascular endothelial growth factor (VEGF) were quantified by ELISA...
April 2, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29621507/internal-limiting-membrane-peeling-in-macula-off-retinal-detachment-complicated-by-grade-b-proliferative-vitreoretinopathy
#20
Pauline Foveau, Bertrand Leroy, Jean-Paul Berrod, Jean-Baptiste Conart
PURPOSE: To investigate the clinical benefit of internal limiting membrane (ILM) peeling as a surgical adjunct in the repair of primary retinal detachment (RD) complicated by grade B proliferative vitreoretinopathy (PVR). DESIGN: Retrospective, interventional, comparative case series. METHODS: SETTING: Institutional. STUDY POPULATION: 75 consecutive patients who underwent vitrectomy for primary macula off RD complicated by grade B PVR...
April 2, 2018: American Journal of Ophthalmology
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