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American Journal of Ophthalmology

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https://www.readbyqxmd.com/read/28647462/optical-coherence-tomography-angiography-of-macular-features-after-proton-beam-radiotherapy-for-small-choroidal-melanoma
#1
Alexandre Sellam, Florence Coscas, Livia Lumbroso-Le Rouic, Rémi Dendale, Marco Lupidi, Gabriel Coscas, Laurence Desjardins, Nathalie Cassoux
PURPOSE: To describe the macular features of patients treated with proton beam therapy for choroidal melanoma (CM), using the optical coherence tomography-angiography (OCTA). DESIGN: Retrospective case-control study. METHODS: This study included patients treated with proton beam radiotherapy (PBR) for a small CM. Only patients that had received 100% of the dose 60 GyEBR to the macular area were included in the analysis. All the patients have undergone a full ophthalmological examination including: visual acuity, OCT B-scan and OCTA...
June 21, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28647461/toric-intraocular-lenses-versus-peripheral-corneal-relaxing-incisions-for-astigmatism-between-0-75-2-5-dioptres-during-cataract-surgery
#2
Mayank A Nanavaty, Kaveeta K Bedi, Shahnaz Ali, Mathew Holmes, Saul Rajak
PURPOSE: To compare the outcomes following toric intraocular lens (tIOL) or peripheral corneal relaxing incisions (PCRI) for keratometric astigmatism (KA) between 0.75-2.5D during cataract surgery. DESIGN: Prospective, randomized clinical trial. METHODS: 80 eyes (80 participants) received either tIOL or PCRI and were assessed preoperatively, 1,3,6 and 12 months postoperatively. PRIMARY OUTCOME MEASURE: Un-corrected (UCDVA) and best-corrected distance LogMAR visual acuity (BCDVA) at 12 months...
June 21, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28624326/randomized-trial-on-illuminated-microcatheter-circumferential-trabeculotomy-versus-conventional-trabeculotomy-in-congenital-glaucoma
#3
Jyoti Shakrawal, Shveta Bali, Talvir Sidhu, Saurabh Verma, Ramanjit Sihota, Tanuj Dada
PURPOSE: To compare one year outcomes of illuminated microcatheter-assisted circumferential trabeculotomy(IMCT) vs conventional partial trabeculotomy(CPT) for Primary Congenital Glaucom (PCG). DESIGN: Randomized clinical trial METHODS: Forty eyes of 31 patients with unilateral or bilateral primary congenital glaucoma aged less than two years were randomized to undergo IMCT (20 eyes) or CPT (20 eyes). Primary outcome measure was IOP reduction. The success criterion was defined as intraocular pressure (IOP) ≤ 12 mm Hg without and with anti-glaucoma medications (absolute success and qualified success respectively)...
June 14, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28624325/treat-and-extend-therapy-using-aflibercept-for-neovascular-age-related-macular-degeneration-a-prospective-clinical-trial
#4
Francis Char DeCroos, David Reed, Murtaza K Adam, David Salz, Omesh P Gupta, Allen C Ho, Carl D Regillo
PURPOSE: To determine the efficacy and durability of aflibercept utilized in a treat and extend (TAE) regimen for neovascular age-related macular degeneration (NVAMD). DESIGN: Multicenter, prospective, open label, non-comparative, interventional study METHODS: Forty eyes of 40 patients with treatment-naïve NVAMD were managed with a TAE regimen of intravitreal aflibercept. The main endpoints were the change in mean and median best-corrected visual acuity from baseline at years 1 and 2...
June 14, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28624324/risk-factors-for-rapid-glaucoma-disease-progression
#5
Thomas Chun Wai Chan, Chandra Bala, Anna Siu, Fiona Wan, Andrew White
PURPOSE: To determine the intraocular and systemic risk factor differences between a cohort of rapid glaucoma disease progressors and non-rapid disease progressors. DESIGN: Retrospective case control study Methods SETTING: Five private ophthalmology clinics STUDY POPULATION: 48 rapidly progressing eyes (progression ≥1dB mean deviation (MD)/year) and 486 non-rapidly progressing eyes (progression <1dB MD/year). Patients were eligible if they had a diagnosis of glaucoma from their ophthalmologist and if they had greater than or equal to 5 Humphrey visual fields (24-2) conducted...
June 14, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28624323/post-receptor-neuronal-loss-in-intermediate-age-related-macular-degeneration
#6
Enrico Borrelli, Nizar Saleh Abdelfattah, Akihito Uji, Muneeswar Gupta Nittala, David S Boyer, SriniVas R Sadda
PURPOSE: To investigate the relationship between ganglion cell complex (GCC) thickness and photoreceptor alterations in eyes with intermediate age-related macular degeneration (AMD). DESIGN: Retrospective case-control study. METHODS: We collected data from 68 eyes with intermediate AMD from 68 patients with spectral domain optical coherence tomography (SD-OCT) imaging. A control group of 50 eyes from 50 healthy subjects was included for comparison...
June 14, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28601586/evaluating-structural-progression-of-retinitis-pigmentosa-after-cataract-surgery
#7
Joaquin O De Rojas, Kaspar Schuerch, Priya M Mathews, Thiago Cabral, Albert Hazan, Janet Sparrow, Stephen H Tsang, Leejee H Suh
PURPOSE: To determine whether cataract surgery accelerates disease progression in retinitis pigmentosa (RP). DESIGN: Retrospective cohort study. METHODS: Seventy eyes of 40 patients with RP were categorized as having had phacoemulsification with intraocular lens implantation versus no cataract surgery at a single tertiary-level institution. Spectral domain optical coherence tomography (SD-OCT) was used to measure the ellipsoid zone (EZ) width, which has been demonstrated to be a reliable marker of RP severity, at baseline and throughout follow-up (median 768 days)...
June 7, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28600149/retinal-detachment-associated-with-basketball-related-eye-trauma
#8
Tsung-Han Lee, Yi-Hao Chen, Hsi-Kung Kuo, Yung-Jen Chen, Chih-Hsin Chen, Jong-Jer Lee, Pei-Chang Wu
PURPOSE: Basketball is a popular sport involving significant body contact, which may frequently result in ocular trauma. The aim of this study was to evaluate the characteristics and visual outcomes of retinal detachment associated with basketball-related injury. DESIGN: Retrospective, interventional case series. METHODS: We reviewed the course of patients who sustained traumatic retinal detachment from basketball-related ocular trauma between 2003 and 2015...
June 6, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28579064/practice-patterns-among-eye-care-providers-at-us-teaching-hospitals-with-regards-to-assessing-and-educating-patients-about-smoking
#9
Zachary C Landis, Ramunas Rolius, Ingrid U Scott
PURPOSE: To investigate practice patterns of eye care providers at academic medical centers in the United States (US) with regards to assessing patients' smoking status and exposure, educating patients regarding ocular risks of smoking, and counseling patients about smoking cessation. DESIGN: Cross-sectional survey. METHODS: An anonymous survey including multiple choice and Likert-style questions was constructed on http://www.surveymonkey...
June 1, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28579063/choroidal-changes-associated-with-subretinal-drusenoid-deposits-in-age-related-macular-degeneration-using-swept-source-oct
#10
Inês Laíns, Jay Wang, Joana Providência, Steven Mach, Pedro Gil, João Gil, Marco Marques, Grayson Armstrong, Shady Garas, Patrícia Barreto, Ivana K Kim, Demetrios G Vavvas, Joan W Miller, Deeba Husain, Rufino Silva, John B Miller
PURPOSE: To compare choroidal vascular features of eyes with and without subretinal drusenoid deposits (SDD), using swept-source optical coherence tomography (SS-OCT). DESIGN: Multicenter, cross-sectional study. METHODS: We prospectively recruited patients with intermediate age-related macular degeneration (AMD), without other vitreoretinal pathology. All participants underwent complete ophthalmic exam, color fundus photography (used for AMD staging), and spectral-domain OCT (to evaluate the presence of SDD)...
June 1, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28579062/distribution-of-nonperfusion-area-on-ultra-widefield-fluorescein-angiography-in-eyes-with-diabetic-macular-edema-dave-study
#11
Wenying Fan, Kang Wang, Khalil Ghasemi Falavarjani, Min Sagong, Akihito Uji, Michael Ip, Charles C Wykoff, David M Brown, Jano van Hemert, SriniVas R Sadda
PURPOSE: To explore the distribution of nonperfusion area (NPA) in eyes with diabetic macular edema (DME) and its relationship with the severity of DME. DESIGN: Prospective, observational case series. METHODS: Forty eyes of 29 patients with treatment-naïve DME who participated in the DAVE study (NCT01552408) were included. Ultra-widefield fluorescein angiography images were sent to the Doheny Image Reading Center, where they were montaged and corrected using stereographic projection to adjust for peripheral distortion...
June 1, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28579061/classification-of-fluorescein-breakup-patterns-a-novel-method-of-differential-diagnosis-for-dry-eye
#12
Norihiko Yokoi, Georgi As Georgiev, Hiroaki Kato, Aoi Komuro, Yukiko Sonomura, Chie Sotozono, Kazuo Tsubota, Shigeru Kinoshita
PURPOSE: To investigate the relationship between fluorescein breakup patterns (FBUPs) and clinical manifestations in dry-eye cases. DESIGN: Cross-sectional study. METHODS: In 106 eyes of 106 subjects (19 males, 87 females; mean age: 64.2 years), FBUPs were categorized into 1 of the following 5 break (B) types: area (AB, n=19); spot (SB, n=22); line (LB, n=24); dimple (DB, n=19); random (RB, n=22 eyes), and dry-eye-related symptoms using the visual analog scale (VAS, 100mm=maximum), tear meniscus radius (TMR, mm), tear-film lipid-layer interference grade (IG) (grades 1-5; 1=best) and spread grade (SG) (grades 1-4; 1=best), tear-film non-invasive breakup time (NIBUT, seconds), FBU time (FBUT, seconds), corneal-epithelial damage (CED) score (15 points=maximum), ocular-surface epithelial damage (OSED) score (9 points=maximum), and the Schirmer 1 test (ST1, mm) were examined and compared between each FBUP...
June 1, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28577756/regeneration-of-photoreceptor-outer-segments-after-scleral-buckling-surgery-for-rhegmatogenous-retinal-detachment
#13
LETTER
Eimei Ra, Yasuki Ito, Kenichi Kawano, Takeshi Iwase, Hiroki Kaneko, Shinji Ueno, Shunsuke Yasuda, Keiko Kataoka, Hiroko Terasaki
No abstract text is available yet for this article.
May 31, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28577755/regeneration-of-photoreceptor-outer-segments-after-scleral-buckling-surgery-for-rhegmatogenous-retinal-detachment
#14
LETTER
Anurag Badhani, Umesh Chandra Behera
No abstract text is available yet for this article.
May 31, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28572063/pattern-of-local-recurrence-after-i-125-episcleral-brachytherapy-for-uveal-melanoma-in-a-spanish-referral-ocular-oncology-unit
#15
Sara Sánchez-Tabernero, Ciro García-Alvarez, Ma Fe Muñoz-Moreno, Patricia Diezhandino, Pilar Alonso-Martínez, Jesus M de Frutos-Baraja, Francisco López-Lara, Maria A Saornil
PURPOSE: To describe the time, frequency, and clinical characteristics of treatment failure after I-125 brachytherapy in patients with uveal melanoma treated and followed in a Spanish referral ocular oncology unit. DESIGN: Prospective, consecutive, interventional case series. METHODS: Patients diagnosed with uveal melanoma from 1995 to 2016 and treated with episcleral brachytherapy were included. Demographic data collection, ophthalmic evaluation, ultrasound scan, and systemic studies were performed at baseline, every six months thereafter for five years, and subsequently at annual intervals...
May 29, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28572062/the-united-kingdom-diabetic-retinopathy-electronic-medical-record-users-group-report-3-baseline-retinopathy-and-clinical-features-predict-progression-of-diabetic-retinopathy
#16
Cecilia S Lee, Aaron Y Lee, Douglas Baughman, Dawn Sim, Toks Akelere, Christopher Brand, David P Crabb, Alastair K Denniston, Louise Downey, Alan Fitt, Rehna Khan, Sajad Mahmood, Kaveri Mandal, Martin Mckibbin, Geeta Menon, Aires Lobo, B Vineeth Kumar, Salim Natha, Atul Varma, Elizabeth Wilkinson, Danny Mitry, Clare Bailey, Usha Chakravarthy, Adnan Tufail, Catherine Egan
PURPOSE: To determine the time and risk factors for developing proliferative diabetic retinopathy (PDR) and vitreous hemorrhage (VH) DESIGN: Multicenter, national cohort study METHODS: Anonymized data of 50,254 patient eyes with diabetes mellitus at 19 UK hospital eye services were extracted at the initial and follow-up visits between 2007 and 2014. Time to progression of PDR and VH were calculated with Cox regression after stratifying by baseline diabetic retinopathy (DR) severity and adjusting for age, gender, race, and starting visual acuity...
May 29, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28554552/orbital-and-orbitocranial-trauma-from-pencil-fragments-role-of-timely-diagnosis-and-management
#17
Won-Kyung Cho, Audrey C Ko, Habibullah Eatamadi, Abdelqadir Al-Ali, Jean-Paul Abboud, Don O Kikkawa, Bobby S Korn
PURPOSE: To emphasize the importance of early detection and radiologic evaluation of retained organic foreign bodies (FBs) in orbital or orbitocranial penetrating injuries by pencil. DESIGN: Retrospective case series. METHODS: A retrospective chart review of patients who had penetrating orbital or orbitocranial trauma at two tertiary hospitals was conducted. Patients whose mechanism of injury was penetrating trauma by pencil were included...
May 26, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28549849/optimizing-glaucoma-screening-in-high-risk-population-design-and-1-year-findings-of-the-screening-to-prevent-stop-glaucoma-study
#18
Di Zhao, Eliseo Guallar, Prateek Gajwani, Bonnielin Swenor, John Crews, Jinan Saaddine, Lucy Mudie, Varshini Varadaraj, David S Friedman
PURPOSE: To develop, implement, and evaluate replicable community-based screening intervention designed to improve glaucoma and other eye disease detection and follow-up care in high-risk populations in the United States. We present the design of the study and describe the findings of the first year of the program. DESIGN: Prospective study to evaluate screening and follow-up. METHODS: This is an ongoing study to develop an eye screening program using trained personnel to identify individuals with ophthalmic needs, focusing on African Americans ≥50 years of age at multiple inner-city community sites in Baltimore, MD...
May 23, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28549848/relationship-between-visual-acuity-and-retinal-thickness-during-anti-vascular-endothelial-growth-factor-therapy-for-retinal-diseases
#19
William C Ou, David M Brown, John F Payne, Charles C Wykoff
PURPOSE: Investigate the relationship between best-corrected visual acuity (BCVA) and central retinal thickness (CRT) in eyes receiving ranibizumab for three common retinal diseases. DESIGN: Retrospective analysis of clinical trial data METHODS: Early Treatment Diabetic Retinopathy Study BCVA and spectral-domain optical coherence tomography measured CRT of 387 eyes of 345 patients enrolled in six prospective clinical trials for management of neovascular age-related macular degeneration (AMD), diabetic macular edema (DME), and retinal vein occlusion (RVO) were evaluated by Pearson correlation and linear regression...
May 23, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28549847/trends-in-hospitalization-and-incidence-rate-for-syphilitic-uveitis-in-the-united-states-from-1998-2009
#20
Thomas Albini, Natalia F Callaway, Suzann Pershing, Sean K Wang, Andrew A Moshfeghi, Darius M Moshfeghi
PURPOSE: This study evaluates the annual incidence of syphilitic uveitis in the US and trends in hospital admissions over time. DESIGN: Retrospective, longitudinal incidence rate analysis of the National Inpatient Sample (NIS) data from 1998 to 2009. METHODS: The NIS is a de-identified, random sample dataset of inpatient hospitalizations from 46 states. The number of cases of syphilitic uveitis was defined: 1) ICD-9 code for syphilis and uveitis or 2) ICD-9 code for syphilitic uveitis...
May 23, 2017: American Journal of Ophthalmology
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