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American Journal of Geriatric Psychiatry

Sarah Forrester
No abstract text is available yet for this article.
November 9, 2016: American Journal of Geriatric Psychiatry
Adam Simning, Yeates Conwell
No abstract text is available yet for this article.
November 8, 2016: American Journal of Geriatric Psychiatry
Masayuki Noguchi, Tomoko Kobayashi, Toshihide Iwase, Etsuji Suzuki, Ichiro Kawachi, Soshi Takao
OBJECTIVE: Social capital, the collective resources of groups including perceptions of trust and reciprocity, is recognized as an important contributor to suicide. We examined the association of individual- and community-level social capital with suicidal ideation after adjusting for social support among older adults living in the community. METHODS: In August 2010 we sent questionnaires to all residents aged 65 years and older living in 3 rural municipalities (N = 21,232) in Okayama Prefecture, Japan; 13,919 questionnaires were returned (response rate: 65...
November 4, 2016: American Journal of Geriatric Psychiatry
Philip D Harvey
No abstract text is available yet for this article.
October 27, 2016: American Journal of Geriatric Psychiatry
Laura B Zahodne, Paola Gilsanz, M Maria Glymour, Laura E Gibbons, Paul Brewster, Jamie Hamilton, Jesse Mez, Jessica R Marden, Kwangsik Nho, Eric B Larson, Paul K Crane, Alden L Gross
OBJECTIVE: Numerous studies show that depressive symptoms measured at a single assessment predict greater future stroke risk. Longer-term symptom patterns, such as variability across repeated measures or worst symptom level, might better reflect adverse aspects of depression than a single measurement. This prospective study compared five approaches to operationalizing depressive symptoms at annual assessments as predictors of stroke incidence. DESIGN: Cohort followed for incident stroke over an average of 6...
October 24, 2016: American Journal of Geriatric Psychiatry
Hochang B Lee, Mark A Oldham, Frederick E Sieber, Esther S Oh
OBJECTIVES: We evaluated whether delirium after hip fracture repair modifies the relationship between baseline dementia and one-year mortality after surgery. METHODS: Patients age 65 years and older undergoing hip fracture repair surgery at John Hopkins Bayview Medical Center between 1999 and 2009 were eligible for this prospective cohort study. Baseline probable dementia was defined as either preoperatively diagnosed dementia per geriatrician or score less than 24 on the Mini-Mental State Examination...
October 19, 2016: American Journal of Geriatric Psychiatry
Ellen E Lee, Suzi Hong, Averria Sirkin Martin, Lisa T Eyler, Dilip V Jeste
OBJECTIVE: Inflammation may play a role in the accelerated physical aging reported in schizophrenia, though biomarker findings and associations with demographic and clinical factors are inconsistent. METHODS: In a cross-sectional, case-control design, 95 outpatients with schizophrenia (mean age ± SD: 48.1 ± 10.2 years) and 95 demographically comparable healthy comparison subjects (HCs) (mean age ± SD: 48.1 ± 12.1 years) were studied. Sociodemographic and clinical data were collected, and plasma levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and interferon-γ (IFN-γ) were assayed...
October 17, 2016: American Journal of Geriatric Psychiatry
Vonetta M Dotson
No abstract text is available yet for this article.
October 13, 2016: American Journal of Geriatric Psychiatry
Kevin J Manning, Grace Chan, David C Steffens
OBJECTIVES: Neuroticism is a broad construct that conveys a predisposition to experience psychological distress and negative mood states. Vulnerability to stress (VS) is one neuroticism trait that has been linked to worse mood and cognitive outcomes in older adults. We hypothesized that elevated VS would be associated with worse illness course and cognitive decline in older adults with late-life major depression (LLD). DESIGN: Participants were enrolled in the Neurocognitive Outcomes of Depression in the Elderly (NCODE), a longitudinal investigation of the predictors of poor illness course and cognitive decline in LLD...
October 13, 2016: American Journal of Geriatric Psychiatry
Amy Lin, Jenny Brook, Joshua D Grill, Edmond Teng
OBJECTIVE: Clinical trials in incipient and clinical Alzheimer disease (AD) often include informant-reported outcomes. Whereas informant reports in AD dementia may be modulated by the nature of participant-informant relationships, whether informant type affects reporting at earlier disease stages is less certain. We sought to determine the effects of participant-informant relationships on informant assessments of quality of life (QOL), functional abilities, and behavioral symptoms in individuals with normal cognition (NC), mild cognitive impairment (MCI), and mild-to-moderate AD dementia...
October 13, 2016: American Journal of Geriatric Psychiatry
Eva Pirogovsky-Turk, Raeanne C Moore, J Vincent Filoteo, Irene Litvan, David D Song, Stephanie L Lessig, Dawn M Schiehser
OBJECTIVES: To examine the relationship between anxiety, depression, apathy, and cognitive decline in Parkinson disease (PD). DESIGN: Longitudinal study design to assess whether specific neuropsychiatric, demographic, and clinical features predict future cognitive decline. SETTING: Veterans Affairs San Diego Medical Center and the University of California, San Diego. PARTICIPANTS: PD patients (N = 68) and healthy controls (N = 30)...
October 12, 2016: American Journal of Geriatric Psychiatry
Joan K Monin, Natalie Mota, Becca Levy, John Pachankis, Robert H Pietrzak
OBJECTIVES: Objectives were to: (a) identify the mental health needs of older and younger sexual minority and heterosexual U.S. veterans and (b) examine whether sexual minority status confers vulnerability or resiliency in older adulthood. Support and trauma exposure were examined as potential mechanisms for age by sexual orientation differences. METHODS: Participants were a nationally representative sample of 3,095 U.S. veterans (ages 21 to 96 years). Measures included demographics, military characteristics, sexual orientation (lesbian, gay, or bisexual; LGB), social support, trauma, and mental health indicators (lifetime and present depression and post-traumatic stress disorder (PTSD); lifetime anxiety and suicidal ideation)...
September 23, 2016: American Journal of Geriatric Psychiatry
Sara K Mamo, Olivia Nirmalasari, Carrie L Nieman, Matthew K McNabney, Allison Simpson, Esther S Oh, Frank R Lin
OBJECTIVE: Hearing loss is a commonly unmet need among adults with dementia that may exacerbate common dementia-related behavioral symptoms. Accessing traditional audiology services for hearing loss is a challenge because of high cost and time commitment. To improve accessibility and affordability of hearing treatment for persons with dementia, there is a need for unique service delivery models. The purpose of this study is to test a novel hearing intervention for persons with dementia and family caregivers delivered in outpatient settings...
September 22, 2016: American Journal of Geriatric Psychiatry
Annemiek Dols, Filip Bouckaert, Pascal Sienaert, Didi Rhebergen, Kristof Vansteelandt, Mara Ten Kate, Francois-Laurent de Winter, Hannie C Comijs, Louise Emsell, Mardien L Oudega, Eric van Exel, Sigfried Schouws, Jasmien Obbels, Mike Wattjes, Frederik Barkhof, Piet Eikelenboom, Mathieu Vanderbulcke, Max L Stek
OBJECTIVE: The clinical profile of late-life depression (LLD) is frequently associated with cognitive impairment, aging-related brain changes, and somatic comorbidity. This two-site naturalistic longitudinal study aimed to explore differences in clinical and brain characteristics and response to electroconvulsive therapy (ECT) in early- (EOD) versus late-onset (LOD) late-life depression (respectively onset <55 and ≥55 years). METHODS: Between January 2011 and December 2013, 110 patients aged 55 years and older with ECT-treated unipolar depression were included in The Mood Disorders in Elderly treated with ECT study...
September 22, 2016: American Journal of Geriatric Psychiatry
Natalia A Skritskaya, Christine Mauro, Matthew Olonoff, Xin Qiu, Sarah Duncan, Yuanjia Wang, Naihua Duan, Barry Lebowitz, Charles F Reynolds, Naomi M Simon, Sidney Zisook, M Katherine Shear
OBJECTIVES: Maladaptive cognitions related to loss are thought to contribute to development of complicated grief and are crucial to address in treatment, but tools available to assess them are limited. This paper introduces the Typical Beliefs Questionnaire (TBQ), a 25-item self-report instrument to assess cognitions that interfere with adaptation to loss. DESIGN: Study participants completed an assessment battery during their initial evaluation and again after completing treatment at 20 weeks...
September 19, 2016: American Journal of Geriatric Psychiatry
William M McDonald
There is increasing evidence for the efficacy of neuromodulation in the treatment of resistant mood disorders and emerging data supporting the use of neuromodulation in cognitive disorders. A significant minority of depressed elders do not respond to pharmacotherapy and/or psychotherapy. This has led clinicians to recommend the increasing use of electroconvulsive therapy (ECT) in the treatment of medication-resistant or life-threatening geriatric depression. Multiple studies have supported the safety and efficacy of ECT in the elderly, yet ECT is associated with side effects including cardiovascular and cognitive side effects...
December 2016: American Journal of Geriatric Psychiatry
Larry E Tune
No abstract text is available yet for this article.
December 2016: American Journal of Geriatric Psychiatry
Charles F Reynolds
No abstract text is available yet for this article.
December 2016: American Journal of Geriatric Psychiatry
Jacob Taylor, William S Anderson, Jason Brandt, Zoltan Mari, Gregory M Pontone
Although Parkinson disease (PD) is defined clinically by its motor symptoms, it is increasingly recognized that much of the disability and worsened quality of life experienced by patients with PD is attributable to psychiatric symptoms. The authors describe a model of multidisciplinary care that enables these symptoms to be effectively managed. They describe neuropsychiatric complications of PD itself and pharmacologic and neurostimulation treatments for parkinsonian motor symptoms and discuss the management of these complications...
December 2016: American Journal of Geriatric Psychiatry
D P Devanand
Several recently developed biomarkers of Alzheimer disease (AD) are invasive, expensive, and difficult to obtain in most clinical settings. Olfactory identification test performance represents a noninvasive, inexpensive biomarker of AD that may have predictive accuracy comparable with neuroimaging measures and biomarkers assessed in cerebrospinal fluid. Neurofibrillary tangles in the olfactory bulb are among the earliest pathologic features of AD and are also seen in the projection pathways from the olfactory bulb to secondary olfactory brain regions, including the piriform and medial temporal cortex, orbitofrontal cortex, and other limbic regions...
December 2016: American Journal of Geriatric Psychiatry
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