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American Journal of Geriatric Psychiatry

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https://www.readbyqxmd.com/read/30098857/scientific-biography-of-a-mid-career-physician-scientist-getting-by-with-help-from-my-friends
#1
EDITORIAL
Eric J Lenze
No abstract text is available yet for this article.
August 8, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30120018/memory-mood-and-marriage-examining-the-interplay-in-older-adults
#2
EDITORIAL
Ellen E Lee, Meera Balasubramaniam
No abstract text is available yet for this article.
August 4, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30017237/refining-delirium-a-transtheoretical-model-of-delirium-disorder-with-preliminary-neurophysiologic-subtypes
#3
Mark A Oldham, Joseph H Flaherty, Jose R Maldonado
The development of delirium indicates neurophysiologic disruption and predicts unfavorable outcomes. This relationship between delirium and its outcomes has inspired a generation of studies aimed at identifying, predicting, and preventing both delirium and its associated sequelae. Despite this, evidence on delirium prevention and management remains limited. No medication is approved for the prevention or treatment of delirium or for its associated psychiatric symptoms. This unmet need for effective delirium treatment calls for a refined approach...
July 12, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30100268/fda-approval-of-pimavanserin-response-to-absence-of-evidence-versus-evidence-of-absence-pimavanserin-and-the-saps-pd
#4
EDITORIAL
Sarah Schubmehl, Joleen Sussman
No abstract text is available yet for this article.
July 7, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30077588/absence-of-evidence-versus-evidence-of-absence-saps-pd
#5
EDITORIAL
Ankur A Butala, Gregory M Pontone
No abstract text is available yet for this article.
July 7, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30064870/stress-inflammation-and-aging-an-association-beyond-chance
#6
EDITORIAL
Breno Satler Diniz, Erica Marciano Vieira
No abstract text is available yet for this article.
July 7, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30120019/longitudinal-associations-between-cognitive-functioning-and-depressive-symptoms-among-older-adult-spouses-in-the-cardiovascular-health-study
#7
Joan K Monin, Margaret Doyle, Peter H Van Ness, Richard Schulz, Richard A Marottoli, Kira Birditt, Brooke C Feeney, Trace Kershaw
OBJECTIVE: To examine the bidirectional associations between older adult spouses' cognitive functioning and depressive symptoms over time. DESIGN: Longitudinal, dyadic path analysis with the actor-partner interdependence model. SETTING: Data were from visit 5 (1992/1993), visit 8 (1995/1996), and visit 11 (1998/1999) of the Cardiovascular Health Study, a multisite, longitudinal, observational study of risk factors for cardiovascular disease in adults 65 years or older...
July 3, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30082208/psychometric-properties-of-an-abbreviated-version-of-the-apathy-evaluation-scale-for-parkinson-disease-aes-12pd
#8
Yuliya Stankevich, Ulrike Lueken, Monika Balzer-Geldsetzer, Richard Dodel, Susanne Gräber-Sultan, Daniela Berg, Inga Liepelt-Scarfone, Rüdiger Hilker-Roggendorf, Elke Kalbe, Oliver Kaut, Brit Mollenhauer, Kathrin Reetz, Eva Schäffer, Nele Schmidt, Jörg B Schulz, Annika Spottke, Karsten Witt, Katharina Linse, Alexander Storch, Oliver Riedel
BACKGROUND: Apathy is a frequent symptom in Parkinson's disease (PD), substantially aggravating the course of PD. Regarding the accumulating evidence of the key role of apathy in PD, time-efficient assessments are useful for fostering progress in research and treatment. The Apathy Evaluation Scale (AES) is widely used for the assessment of apathy across different nosologies. OBJECTIVE: To facilitate the application of the AES in PD, we reduced the AES to two-thirds its length and validated this abbreviated version...
June 30, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30093218/microvascular-endothelial-function-and-neurocognition-among-adults-with-major-depressive-disorder
#9
Patrick J Smith, James A Blumenthal, Alan L Hinderliter, Lana L Watkins, Benson M Hoffman, Andrew Sherwood
BACKGROUND: Cardiovascular risk factors (CVRFs) and endothelial dysfunction have been associated independently with poorer neurocognition in middle-aged adults, particularly on tests of frontal lobe function. However, to our knowledge, no studies have examined markers of microvascular dysfunction on neurocognition or the potential interaction between macro- and microvascular biomarkers on neurocognition in middle-aged and older adults with major depressive disorder (MDD). METHODS: Participants included 202 adults with MDD who were not receiving mental health treatment...
June 28, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30037778/donepezil-treatment-in-patients-with-depression-and-cognitive-impairment-on-stable-antidepressant-treatment-a-randomized-controlled-trial
#10
Davangere P Devanand, Gregory H Pelton, Kristina D'Antonio, Adam Ciarleglio, Jennifer Scodes, Howard Andrews, Julia Lunsford, John L Beyer, Jeffrey R Petrella, Joel Sneed, Michaela Ciovacco, Pudugramam Murali Doraiswamy
OBJECTIVE: Depression and cognitive impairment are often comorbid in older adults, but optimal treatment strategies remain unclear. In a two-site study, the efficacy and safety of add-on donepezil versus placebo were compared in depressed patients with cognitive impairment receiving stable antidepressant treatment. METHODS: A randomized, double-blind, placebo-controlled trial was conducted in older adults with depression and cognitive impairment (https://clinicaltrials...
June 28, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30076080/hospital-elder-life-program-systematic-review-and-meta-analysis-of-effectiveness
#11
Tammy T Hshieh, Tinghan Yang, Sarah L Gartaganis, Jirong Yue, Sharon K Inouye
BACKGROUND: Delirium, defined as an acute disorder of attention and cognition with high morbidity and mortality, can be prevented by multicomponent nonpharmacological interventions. The Hospital Elder Life Program (HELP) is the original evidence-based approach targeted to delirium risk factors, which has been widely disseminated. OBJECTIVE: To summarize the current state of the evidence regarding HELP and to highlight its effectiveness and cost savings. METHODS: Systematic review of Ovid MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials from 1999 to 2017, using a combination of controlled vocabulary and keyword terms...
June 26, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30076079/childhood-hunger-and-thoughts-of-death-or-suicide-in-older-adults
#12
Andrew Stickley, Ai Koyanagi, Yosuke Inoue, Mall Leinsalu
OBJECTIVE: There is little research on the effects of childhood hunger on adult mental health. This study examined the association between childhood hunger and recurrent thoughts of death or suicide in older adults. DESIGN: Data collected during the Estonian Health Interview Survey 2006 (N = 2455) were analyzed from adults aged 60 and above. Retrospective information was obtained on the frequency (never, seldom, sometimes, often) of going to bed hungry in childhood and on the presence of recurrent thoughts of death or suicide in the past 4 weeks...
June 25, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30072308/screening-for-executive-dysfunction-in-late-life-depression-utility-of-trail-making-test-and-self-report-measures
#13
David Bickford, Ruth T Morin, Dan Catalinotto, R Scott Mackin, J Craig Nelson
OBJECTIVE: Prior work suggests executive dysfunction (ED) on the Stroop Color and Word Test (SCWT) and the Mattis Dementia Rating Scale-2 Initiation/Perseveration subscale (DRS IP) predicts poor antidepressant response in late-life depression. This study examined if either patient perception of ED or the Trail Making Test Part B (TMT-B) could identify patients with impairment on the SCWT or DRS IP. METHODS: Patients were 65 or older and had a diagnosis of major depression without dementia...
June 25, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30017239/perceived-stress-is-associated-with-accelerated-monocyte-macrophage-aging-trajectories-in-clinically-normal-adults
#14
Kaitlin B Casaletto, Adam M Staffaroni, Fanny Elahi, Emily Fox, Persephone A Crittenden, Michelle You, John Neuhaus, Maria Glymour, Brianne M Bettcher, Kristine Yaffe, Joel H Kramer
OBJECTIVES: Chronic stress is associated with poorer age-related cognition, but the mechanisms of this relationship are not well understood. Aging increases expression of activated macrophages, leading to exacerbated immune responses to stressors. We examined the impact of stress and aging on macrophage-related inflammation and cognition in clinically normal adults. METHODS: Three hundred eighty clinically normal adults were followed longitudinally (age M = 73 years; visit range: 1-8; M = 2...
June 18, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30017238/half-of-home-care-recipients-are-depressed-how-do-we-optimize-their-care
#15
EDITORIAL
Amber M Gum
No abstract text is available yet for this article.
June 18, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30001925/commentary-on-resilience-and-white-matter-integrity-in-geriatric-depression
#16
EDITORIAL
Ellen E Lee, Lisa T Eyler
No abstract text is available yet for this article.
June 18, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29980477/invited-perspective-on-unsolicited-patient-complaints-identify-physicians-with-evidence-of-neurocognitive-disorders
#17
EDITORIAL
Stephanie Collier
No abstract text is available yet for this article.
June 18, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30072307/a-nationwide-population-based-cohort-study-of-dementia-risk-among-acid-suppressant-users
#18
In Cheol Hwang, Jooyoung Chang, Sang Min Park
OBJECTIVE: Data regarding the potential link between acid suppressant use and dementia are inconsistent. This study assessed the association between cumulative exposure to proton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2RAs) and dementia risk among Korean adults. DESIGN AND METHODS: A population-based longitudinal study was conducted using the Korean National Health Insurance Corporation claims database merged with national health examination data for 2002-2013...
June 15, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30072306/perspective-on-pimavanserin-and-the-saps-pd-novel-scale-development-as-a-means-to-fda-approval
#19
EDITORIAL
Sarah Schubmehl, Joleen Sussman
In 2016, pimavanserin, a 5-hydroxytryptamine 2A inverse agonist, became the first U.S. Food and Drug Administration (FDA) approved medication for Parkinson disease psychosis (PDP) after demonstrating modest clinical improvement in a single positive trial as assessed by a novel PDP scale, the Scale for the Assessment of Positive Symptoms for Parkinson's Disease Psychosis (SAPS-PD). This followed three trials that demonstrated negative findings on established measures of psychosis widely used in PDP research, including the Brief Psychiatric Rating Scale, the Scale for the Assessment of Positive Symptoms, the Parkinson Psychosis Rating Scale, and the Clinical Global Impression-Severity Scale...
June 14, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/30049599/the-storm
#20
EDITORIAL
David L Coulter
No abstract text is available yet for this article.
June 5, 2018: American Journal of Geriatric Psychiatry
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