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American Journal of Geriatric Psychiatry

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https://www.readbyqxmd.com/read/28320582/caregiver-vulnerability-and-brain-structural-markers-compounding-risk
#1
EDITORIAL
Janice K Kiecolt-Glaser, Stephanie J Wilson
No abstract text is available yet for this article.
February 28, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28318798/identification-of-childhood-abuse-in-patients-with-late-life-depression-may-help-to-optimize-treatment
#2
EDITORIAL
Elisabeth Schramm, Anneke van Schaik
No abstract text is available yet for this article.
February 24, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28341138/depression-is-associated-with-increased-risk-for-metabolic-syndrome-in-latinos-with-type-2-diabetes
#3
Veronica Cardenas, Brent T Mausbach, David Sommerfeld, Daniel Jimenez, Roland von Känel, Jennifer S Ho, Piedad Garcia, Gregory A Aarons
OBJECTIVE: Latino adults are 66% more likely to have diabetes relative to non-Latino white adults. Prior research identifies depression as a significant risk factor for metabolic syndrome (MetS), but research examining this among Latinos is lacking. This study sought to examine the links between depression and MetS and clinically significant elevations in cardiovascular disease risk markers of MetS in a sample of community-dwelling older Latinos with type 2 diabetes. METHODS: Participants were 332 community-dwelling older (≥60 years) Latinos with type 2 diabetes who completed the nine-item Patient Health Questionnaire and received a health checkup assessing body mass index (BMI), triglyceride and high-density lipoprotein (HDL) cholesterol levels, and blood pressure...
February 22, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28336265/brain-structural-markers-and-caregiving-characteristics-as-interacting-correlates-of-caregiving-strain
#4
Stephen F Smagula, Scott Beach, Andrea L Rosso, Anne B Newman, Richard Schulz
OBJECTIVE: To evaluate the association between brain structural markers and caregiving strain among older informal caregivers. DESIGN: A secondary data analysis combining data from the Caregiver Health Effects Study (1993-1994) and the Cardiovascular Health Study MRI examination (1992-1994). SETTING: Four United States communities. PARTICIPANTS: Co-residing spousal caregivers (N = 237; mean age: 76.2 years, SD: 2...
February 21, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28342644/steeper-slope-of-age-related-changes-in-white-matter-microstructure-and-processing-speed-in-bipolar-disorder
#5
Sheena I Dev, Tanya T Nguyen, Benjamin S McKenna, Ashley N Sutherland, Hauke Bartsch, Rebecca J Theilmann, Lisa T Eyler
OBJECTIVES: Bipolar disorder (BD) is associated with compromised white matter (WM) integrity and deficits in processing speed (PS). Few studies, however, have investigated age relationships with WM structure and cognition to understand possible changes in brain health over the lifespan. This investigation explored whether BD and healthy counterpart (HC) participants exhibited differential age-related associations with WM and cognition, which may be suggestive of accelerated brain and cognitive aging...
February 16, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28302438/antipsychotic-use-and-hospitalization-among-older-assisted-living-residents-does-risk-vary-by-frailty-status
#6
Kathryn J Stock, David B Hogan, Kate Lapane, Joseph E Amuah, Suzanne L Tyas, Susan E Bronskill, Andrew M Morris, Chaim M Bell, Lianne Jeffs, Colleen J Maxwell
OBJECTIVE: To examine associations between baseline frailty measures, antipsychotic use, and hospitalization over 1 year and whether hospitalization risk associated with antipsychotic use varies by frailty level. METHODS: In this prospective cohort study of 1,066 residents (mean age: 85 years; 77% women) from the Alberta Continuing Care Epidemiological Studies, trained research nurses conducted comprehensive resident assessments at baseline (2006-2007) for sociodemographic characteristics, health conditions, frailty status, behavioral problems, and all medications consumed during the past 3 days...
February 16, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28302439/cognitive-deficits-underappreciated-contributors-to-suicide
#7
EDITORIAL
Katalin Szanto
No abstract text is available yet for this article.
February 15, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28314605/increased-elderly-utilization-of-psychiatric-emergency-resources-as-a-reflection-of-the-growing-mental-health-crisis-facing-our-aging-population
#8
LETTER
Brett Y Lu, Jane Onoye, Anson Nguyen, Junji Takeshita, Iqbal Ahmed
No abstract text is available yet for this article.
February 14, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28285770/visual-hallucinations-in-neurodegenerative-diseases-focus-on-selective-tissue-vulnerability
#9
EDITORIAL
Jared T Hinkle, Gregory M Pontone
No abstract text is available yet for this article.
February 14, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28283426/bringing-precision-medicine-to-the-management-of-bpsd
#10
EDITORIAL
Donovan T Maust, Helen C Kales
No abstract text is available yet for this article.
February 14, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28223081/aagp-statement-on-immigration-executive-order-february-7-2017
#11
EDITORIAL
Daniel Sewell, Kirsten Wilkins
No abstract text is available yet for this article.
February 13, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28285771/improvement-in-depression-is-associated-with-improvement-in-cognition-in-late-life-psychotic-depression
#12
Lindsay W Victoria, Ellen M Whyte, Meryl A Butters, Barnett S Meyers, George S Alexopoulos, Benoit H Mulsant, Anthony J Rothschild, Samprit Banerjee, Alastair J Flint
OBJECTIVE: To characterize cognitive function at baseline and investigate the relationship between change in cognition, depression, and psychosis after treatment among older adults with major depressive disorder with psychotic features. METHODS: This was a secondary analysis of a double-blind, randomized, controlled treatment trial at inpatient and outpatient settings at four academic health centers on "Young Old" (aged 60-71 years, N = 71) and "Older" (aged 72-86 years, N = 71) participants diagnosed with psychotic depression...
February 9, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28283427/multimorbidity-and-mental-health
#13
EDITORIAL
Joseph J Gallo
No abstract text is available yet for this article.
February 9, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28279628/who-are-the-seniors-with-subjective-but-not-objective-cognitive-impairment
#14
EDITORIAL
Dilip V Jeste, Graham M L Eglit
No abstract text is available yet for this article.
February 8, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28259698/glycemia-but-not-the-metabolic-syndrome-is-associated-with-cognitive-decline-findings-from-the-european-male-ageing-study
#15
Margot J Overman, Neil Pendleton, Terence W O'Neill, Gyorgy Bartfai, Felipe F Casanueva, Gianni Forti, Giulia Rastrelli, Aleksander Giwercman, Thang S Han, Ilpo T Huhtaniemi, Krzysztof Kula, Michael E J Lean, Margus Punab, David M Lee, Elon S Correa, Tomas Ahern, Michaël R Laurent, Sabine M P Verschueren, Leen Antonio, Evelien Gielen, Martin K Rutter, Dirk Vanderschueren, Frederick C W Wu, Jos Tournoy
OBJECTIVE: Previous research has indicated that components of the metabolic syndrome (MetS), such as hyperglycemia and hypertension, are negatively associated with cognition. However, evidence that MetS itself is related to cognitive performance has been inconsistent. This longitudinal study investigates whether MetS or its components affect cognitive decline in aging men and whether any interaction with inflammation exists. METHODS: Over a mean of 4.4 years (SD ± 0...
February 7, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28318797/early-symptom-trajectories-as-predictors-of-treatment-outcome-for-citalopram-versus-placebo
#16
Sigal Zilcha-Mano, Steven P Roose, Patrick J Brown, Bret R Rutherford
OBJECTIVES: The high percentage of failed clinical trials for anti-depressant medications, especially in elderly populations, obscures the fact that some patients may benefit greatly from treatment. Early detection of patients who may benefit most from antidepressant medication may improve treatment decisions. We examined whether depressed patients in a large clinical trial exhibit distinct trajectories of early symptom change that predict differential response to medication or placebo...
February 3, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28238814/neural-basis-of-cognitive-assessment-in-alzheimer-disease-amnestic-mild-cognitive-impairment-and-subjective-memory-complaints
#17
Jordi A Matías-Guiu, María Nieves Cabrera-Martín, María Valles-Salgado, Alicia Pérez-Pérez, Teresa Rognoni, Teresa Moreno-Ramos, José Luis Carreras, Jorge Matías-Guiu
INTRODUCTION: Interpreting cognitive tests is often challenging. The same test frequently examines multiple cognitive functions, and the functional and anatomical basis underlying test performance is unknown in many cases. This study analyses the correlation of different neuropsychological test results with brain metabolism in a series of patients evaluated for suspected Alzheimer disease. METHODS: 20 healthy controls and 80 patients consulting for memory loss were included, in which cognitive study and (18)F-fluorodeoxyglucose PET were performed...
February 3, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28259697/antipsychotic-use-and-physical-morbidity-in-parkinson-disease
#18
Daniel Weintraub, Claire Chiang, Hyungjin Myra Kim, Jayne Wilkinson, Connie Marras, Barbara Stanislawski, Eugenia Mamikonyan, Helen C Kales
OBJECTIVE: To determine if antipsychotic (AP) use in Parkinson disease (PD) patients is associated with increased physical morbidity. METHODS: Veterans Health Administration data (1999-2010) was used to examine physical morbidity risk associated with AP use in idiopathic PD patients with stable recent physical health. We compared 180-day morbidity rates in patients initiating an AP with matched non-AP users who survived for 180 days (matched on age, sex, race, index year, presence and duration of dementia, PD duration, delirium, hospitalization, Charlson Comorbidity Index, and new non-psychiatric medications; covarying for psychosis)...
February 2, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28215899/-18-f-fluorodeoxyglucose-positron-emission-tomography-cortical-metabolic-activity-associated-with-distinct-agitation-behaviors-in-alzheimer-disease
#19
Gali H Weissberger, Rebecca J Melrose, Theresa A Narvaez, Dylan Harwood, Mark A Mandelkern, David L Sultzer
OBJECTIVE: This study aimed to investigate the neurobiologic correlates of two distinct clusters of agitation symptoms to identify the unique biologic substrates underlying agitated behaviors. METHODS: Eighty-eight outpatients with mild to moderate Alzheimer disease (AD) were recruited from the VA Greater Los Angeles Healthcare System Geropsychiatry Outpatient Program. A cross-sectional investigation was conducted of the relationship between cerebral glucose metabolism measured via (18)F-fluorodeoxyglucose positron emission tomography and agitated symptoms from the Neuropsychiatric Inventory (NPI) in patients with AD...
January 31, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28215900/lack-of-early-improvement-with-antipsychotics-is-a-marker-for-subsequent-nonresponse-in-behavioral-and-psychological-symptoms-of-dementia-analysis-of-catie-ad-data
#20
Kazunari Yoshida, Rachel Roberts, Takefumi Suzuki, Barry Lebowitz, Suzanne Reeves, Robert Howard, Takayuki Abe, Masaru Mimura, Hiroyuki Uchida
OBJECTIVE: Prediction of response or nonresponse to antipsychotics is especially important in patients with behavioral and psychological symptoms of dementia (BPSD) in whom antipsychotic exposure increases risks of death. This study examined whether the presence or absence of early improvement of BPSD with antipsychotics is associated with subsequent response or nonresponse. METHODS: In a post-hoc analysis of the Clinical Antipsychotic Trials of Intervention Effectiveness-Alzheimer's Disease (CATIE-AD) study (2001-2004) (clinicaltrials...
January 30, 2017: American Journal of Geriatric Psychiatry
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