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Allergy

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https://www.readbyqxmd.com/read/30030936/the-soluble-isoform-of-human-fc%C3%A9-ri-is-an-endogenous-inhibitor-of-ige-mediated-mast-cell-responses
#1
Sherezade Moñino-Romero, Lena Erkert, Klara Schmidthaler, Susanne C Diesner, Benjamin F Sallis, Luke Pennington, Theodore Jardetzky, Hans C Oettgen, Barbara Bohle, Edda Fiebiger, Zsolt Szépfalusi
BACKGROUND: The soluble isoform of FcɛRI, the high affinity IgE receptor (sFcεRI), is a protein of the IgE network with poorly defined functions. OBJECTIVE: Define cellular sources and signals that result in the production of human sFcεRI and study its in vivo functions. METHODS: FcεRI-transfected human cell lines (MelJuso), human monocyte-derived dendritic cells (moDCs), and murine bone marrow-derived mast cells (MC) were stimulated by FcεRI crosslinking and release of sFcεRI was analyzed (ELISA, Western Blot)...
July 21, 2018: Allergy
https://www.readbyqxmd.com/read/30030925/de-novo-sensitization-to-aspergillus-fumigatus-in-adult-asthma-over-a-10-year-observation-period
#2
LETTER
Kentaro Watai, Yuma Fukutomi, Hiroaki Hayashi, Yuto Nakamura, Yuto Hamada, Yasuhiro Tomita, Chihiro Mitsui, Yosuke Kamide, Kiyoshi Sekiya, Koichiro Asano, Masami Taniguchi
No abstract text is available yet for this article.
July 21, 2018: Allergy
https://www.readbyqxmd.com/read/30030842/protective-effects-of-breastfeeding-on-respiratory-symptoms-in-infants-with-17q21-asthma-risk-variants
#3
LETTER
Olga Gorlanova, Sabina Illi, Antoaneta A Toncheva, Jakob Usemann, Philipp Latzin, Michael Kabesch, Jean-Charles Dalphin, Roger Lauener, Juha R Pekkanen, Erika Von Mutius, Josef Riedler, Claudia Kuehni, Martin Röösli, Urs Frey
No abstract text is available yet for this article.
July 21, 2018: Allergy
https://www.readbyqxmd.com/read/30028905/the-health-and-economic-outcomes-of-early-egg-introduction-strategies
#4
Marcus Shaker, Kanak Verma, Matthew Greenhawt
BACKGROUND: Studies suggest early egg introduction (EEI) in the first year of life is associated with reduced risk of developing egg allergy. No US recommendations exist regarding optimally implementing EEI. METHODS: Using simulation and Markov modeling over a 20-year horizon, we explored optimal EEI strategies applied to US, European, and Canadian populations, comparing screening of high-risk infants (prick skin testing [PST] or serum specific IgE[sIgE]) before introducing cooked egg at 6 months of life vs...
July 20, 2018: Allergy
https://www.readbyqxmd.com/read/30028518/multi-omics-analysis-points-to-altered-platelet-functions-in-severe-food-associated-respiratory-allergy
#5
D Obeso, L Mera-Berriatua, J Rodríguez-Coira, D Rosace, P Fernandez, I Martin-Antoniano, M Santaolalla, G Marco Martín, T Chivato, M Fernández-Rivas, T Ramos, C Blanco, M I Alvarado, C Domínguez, S Angulo, C Barbas, D Barber, A Villaseñor, M M Escribese
BACKGROUND: Prevalence and severity of allergic diseases have increased worldwide. To date, respiratory allergy phenotypes are not fully characterized and, along with inflammation progression, treatment is increasingly complex and expensive. Profilin sensitization constitutes a good model to study the progression of allergic inflammation. Our aim was to identify the underlying mechanisms and the associated biomarkers of this progression, focusing on severe phenotypes, using transcriptomics and metabolomics...
July 20, 2018: Allergy
https://www.readbyqxmd.com/read/30028515/control-of-allergic-rhinitis-and-asthma-test-carat-with-one-week-recall-validation-of-paper-and-electronic-version
#6
LETTER
B M J Flokstra-de Blok, H J Baretta, J A Fonseca, E van Heijst, B J Kollen, J de Kroon, T van der Molen, I Tsiligianni, C de Jong, J W H Kocks
No abstract text is available yet for this article.
July 20, 2018: Allergy
https://www.readbyqxmd.com/read/30028512/eaaci-position-paper-on-how-to-classify-cutaneous-manifestations-of-drug-hypersensitivity
#7
K Brockow, M Ardern-Jones, M Mockenhaupt, W Aberer, A Barbaud, J C Caubet, R Spiewak, M Torres, C G Mortz
Drug hypersensitivity reactions (DHR) are common and the skin is by far the most frequently involved organ with a broad spectrum of reaction types. The diagnosis of cutaneous DHRs (CDHR) may be difficult because of multiple differential diagnoses. A correct classification is important for the correct diagnosis and management. With these guidelines, we aim to give precise definitions and provide the background needed for doctors to correctly classify CDHR. This article is protected by copyright. All rights reserved...
July 20, 2018: Allergy
https://www.readbyqxmd.com/read/30004595/accidental-allergic-reactions-in-food-allergy-causes-related-to-products-and-patient-s-management
#8
LETTER
Anouska D Michelsen-Huisman, Harmieke van Os-Medendorp, W Marty Blom, Astrid Versluis, Jacqueline J M Castenmiller, Hubert P J M Noteborn, Astrid G Kruizinga, Geert F Houben, André C Knulst
No abstract text is available yet for this article.
July 13, 2018: Allergy
https://www.readbyqxmd.com/read/30003552/persistent-regulatory-t-cell-response-2-years-after-3-years-of-grass-tablet-slit-links-to-reduced-eosinophil-counts-sige-levels-and-clinical-benefit
#9
R Varona, T Ramos, M M Escribese, L Jimeno, A Galán, P A Würtzen, F Vega, A Marín, S Martín, A C Carrera, C Blanco, D Barber
BACKGROUND: In the first 2 years of grass tablet sublingual immunotherapy treatment, we have previously demonstrated a progressive development of a regulatory T-cell response, which was preceded by an early decrease in the frequency of both IL-4+ cells and sIgE levels. A progressive increase of sIgG4 levels and FAB blockage were also found. METHODS: By monitoring immunological kinetics during 3 years of active treatment + 2 follow-up years, we aimed to identify key immunological parameters that could explain sustained clinical benefit of grass tablet sublingual immunotherapy...
July 12, 2018: Allergy
https://www.readbyqxmd.com/read/29999176/provocative-proposal-for-a-revised-nomenclature-for-allergy-and-other-hypersensitivity-diseases
#10
LETTER
Johannes Ring, Jutel Marek, Nikos Papadopoulos, Oliver Pfaar, Cezmi Akdis
No abstract text is available yet for this article.
July 12, 2018: Allergy
https://www.readbyqxmd.com/read/29989179/efficacy-of-omalizumab-150-mg-month-as-a-maintenance-dose-in-patients-with-severe-chronic-spontaneous-urticaria-showing-a-prompt-and-complete-response-to-the-drug
#11
LETTER
https://www.readbyqxmd.com/read/29987908/maternal-pregestational-or-gestational-diabetes-and-childhood-wheezing-a-population-based-cohort-study
#12
LETTER
Xiaoqin Liu, Esben Agerbo, Jiong Li, Shyamali C Dharmage, Reimar W Thomsen, Jørn Olsen, Trine Munk-Olsen
No abstract text is available yet for this article.
July 10, 2018: Allergy
https://www.readbyqxmd.com/read/29987901/epithelial-activators-of-type-2-inflammation-elevation-of-tslp-but-not-il-25-or-il-33-in-chronic-rhinosinusitis-with-nasal-polyps-in-chicago-illinois
#13
LETTER
Noriko Ogasawara, Aiko I Klingler, Bruce K Tan, Julie A Poposki, Kathryn E Hulse, Whitney W Stevens, Anju T Peters, Leslie C Grammer, Kevin C Welch, Stephanie S Smith, David B Conley, Robert C Kern, Robert P Schleimer, Atsushi Kato
No abstract text is available yet for this article.
July 10, 2018: Allergy
https://www.readbyqxmd.com/read/29987892/neuromedin-u-directly-induces-degranulation-of-skin-mast-cells-presumably-via-mrgprx2
#14
Yoshimi Matsuo, Yuhki Yanase, Reiko Irifuku, Shunsuke Takahagi, Shoji Mihara, Kaori Ishii, Tomoko Kawaguchi, Akio Tanaka, Kazumasa Iwamoto, Haruka Watanuki, Kazuyuki Furuta, Satoshi Tanaka, Asuka Inoue, Junken Aoki, Michihiro Hide
No abstract text is available yet for this article.
July 10, 2018: Allergy
https://www.readbyqxmd.com/read/29987879/health-care-resource-utilization-and-costs-associated-with-incremental-systemic-corticosteroid-exposure-in-asthma
#15
Jaco Voorham, Xiao Xu, David Price, Sarowar Golam, Jill Davis, Joanna Ling Zhi Jie, Marjan Kerkhof, Mandy Ow, Trung N Tran
BACKGROUND: Although systemic corticosteroid (SCS) treatment, irrespective of duration or dosage, is associated with adverse outcomes for patients with asthma, the longitudinal effects of this treatment on adverse outcomes, health care resource utilization (HCRU), and health care costs are unknown. METHODS: We identified patients initiating intermittent or long-term SCS who were diagnosed with active asthma from UK general practice with linked secondary care data...
July 10, 2018: Allergy
https://www.readbyqxmd.com/read/29987869/a-missense-mutation-of-the-plasminogen-gene-in-hereditary-angioedema-with-normal-c1-inhibitor-in-japan
#16
LETTER
Hiromasa Yakushiji, Chinami Hashimura, Kazuhito Fukuoka, Arito Kaji, Hisaaki Miyahara, Shinya Kaname, Takahiko Horiuchi
No abstract text is available yet for this article.
July 10, 2018: Allergy
https://www.readbyqxmd.com/read/29987849/type-2-th2-driven-inflammation-impairs-olfactory-sensory-neurogenesis-in-mouse-chronic-rhinosinusitis-model
#17
A Rouyar, M Classe, R Gorski, M-D Bock, J le-Guern, S Roche, V Fourgous, A Remaury, P Paul, C Ponsolles, D Françon, L Rocheteau-Beaujouan, M Clément, E-B Haddad, J-C Guillemot, M Didier, B Biton, C Orsini, V Mikol, M Leonetti
BACKGROUND: Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is a chronic inflammatory disease often accompanied by impairment of sense of smell. This symptom has been somewhat overlooked and its relationship to inflammatory cytokines, tissue compression, neuronal loss, and neurogenesis is still unclear. METHODS: In order to elucidate potential mechanisms leading to CRS in humans, we have established a Type 2/T helper type 2 cell (Th2)-mediated allergic CRS mouse model, based on house dust mite (HDM) and Staphylococcus aureus enterotoxin B (SEB) sensitization...
July 10, 2018: Allergy
https://www.readbyqxmd.com/read/29987846/dietary-assessment-and-the-development-of-asthma-in-korean-adolescents-and-adults
#18
LETTER
Sung-Yoon Kang, Woo-Jung Song, Min-Hye Kim, Sae-Hoon Kim, Sang-Heon Cho, Yoon-Seok Chang, Min-Suk Yang
No abstract text is available yet for this article.
July 10, 2018: Allergy
https://www.readbyqxmd.com/read/29987842/sige-and-sigg-to-airborne-atopic-allergens-coupled-rather-than-inversely-related-responses
#19
LETTER
Rob C Aalberse, Christian Lupinek, Valérie Siroux, Rachel Nadif, Jocelyne Just, Jean Bousquet, Rudolf Valenta, Thomas A Platts-Mills
No abstract text is available yet for this article.
July 10, 2018: Allergy
https://www.readbyqxmd.com/read/29984458/safety-of-ultra-rush-protocols-for-hymenoptera-venom-immunotherapy-in-systemic-mastocytosis
#20
LETTER
V Gruzelle, M Ramassamy, C Bulai Lidiveanu, A Didier, C Mailhol, L Guilleminault
No abstract text is available yet for this article.
July 9, 2018: Allergy
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