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AIDS Patient Care and STDs

Lin Pu, Jingyuan Liu, Yang Luo, Hui Zeng, Hebing Guo, Jingjing Hao, Ningning Yin, Yufeng Liu, Haofeng Xiong, Jian Xiong, Ang Li
To describe the epidemiology, outcomes, and risk factors of acute kidney injury (AKI) among human immunodeficiency virus (HIV)-infected patients admitted to the intensive care unit (ICU).We reviewed all the HIV-infected admissions to the ICU at Beijing Ditan hospital in the time span from June 2005 to May 2017 and collected demographic, clinical, and laboratory data for our sample. AKI was diagnosed and classified according to the Kidney Disease Improving Global Outcomes (KIDIGO) criteria. We analyzed the incidence of AKI and its associated mortality...
September 15, 2018: AIDS Patient Care and STDs
David E Koren, Justin Scott Nichols, Gina M Simoncini
Uptake of HIV pre-exposure prophylaxis (PrEP) is low among women at risk for HIV acquisition. Of 468,000 women, whom the United States Centers for Disease Control and Prevention estimates to be eligible for PrEP, only 10,000 unique women have begun therapy through the third quarter of 2015. These data suggest insufficient HIV prevention efforts. This study, conducted at the site of an urban academic medical center with an emergency department HIV prevalence rate of 4%, assesses the knowledge, attitudes, and beliefs of women toward PrEP...
July 23, 2018: AIDS Patient Care and STDs
Jillian Pintye, Kristin M Beima-Sofie, Pamela A Makabong'O, Anne Njoroge, Susan Brown Trinidad, Renee A Heffron, Jared M Baeten, Connie Celum, Daniel Matemo, John Kinuthia, Maureen C Kelley, Grace C John-Stewart
To optimize scale-up of preexposure prophylaxis (PrEP) for pregnant women at risk of HIV in high HIV burden settings, implementation strategies must be developed that account for perceptions of PrEP in this unique population. Semistructured focus group discussions were conducted with 68 HIV-uninfected Kenyan pregnant and postpartum women without prior PrEP knowledge or experience. A qualitative descriptive analysis was performed, using a constant comparison approach, to identify key themes related to the values and rationale impacting potential PrEP use in pregnancy...
July 23, 2018: AIDS Patient Care and STDs
Valerie Yelverton, Jan Ostermann, Amy Hobbie, Deng Madut, Nathan Thielman
As the number of effective antiretroviral therapy (ART) options increases, there is greater opportunity to involve HIV patients in ART selection. To establish the parameters for a shared ART decision-making process, we sought to identify ART characteristics that are important to patients and understand considerations in ART selection from both patient and provider perspectives. Using a mixed-methods approach, 16 patients and 12 healthcare providers were interviewed, and ranking tasks were conducted with 26 patients to identify ART characteristics that are relevant for shared decision making...
September 2018: AIDS Patient Care and STDs
Mona Duggal, Venkatesan Chakrapani, Lauren Liberti, Veena Satyanarayna, Meiya Varghese, Pushpendera Singh, Mohini Ranganathan, Prabha Chandra, Nancy R Reynolds
We assessed the acceptability of nurse-delivered mobile phone-based counseling to support adherence to antiretroviral treatment (ART) and self-care behaviors among HIV-positive women in India. We conducted open-ended, in-depth interviews with 27 HIV-positive women and 19 key informants at a government ART center in Karnataka, India. Data were analyzed with interpretive techniques. About half of the HIV-positive women owned a mobile phone and many had access to mobile phones of their family members. Most women perceived phone-based counseling as a personalized care approach to get information on demand...
September 2018: AIDS Patient Care and STDs
Barbara S Taylor, Laura Fornos, Jesse Tarbutton, Jana Muñoz, Julie A Saber, Delia Bullock, Roberto Villarreal, Ank E Nijhawan
Initial linkage to medical care is a critical step in the HIV care continuum leading to improved health outcomes, reduced morbidity and mortality, and decreased HIV transmission risk. We explored differences in perspectives on engagement in HIV care between people living with HIV who attended (Arrived) their initial medical provider visit (IMV) and those who did not (Missed), and between patients and providers. The study was conducted in two large majority/minority HIV treatment centers in the United States (US) south, a geographical region disproportionately impacted by HIV...
September 2018: AIDS Patient Care and STDs
Christopher Polk, Sam Webb, Nigel Rozario, Charity G Moore, Alan C Heffner, Michael Leonard
No abstract text is available yet for this article.
September 2018: AIDS Patient Care and STDs
Tyler B Wray, Philip A Chan, Erik Simpanen, Don Operario
HIV self-testing (HST) could be an effective strategy for helping those at high risk test more regularly. However, concerns about HST's lack of follow-up care and referral have so far limited its use. In a pilot, randomized controlled trial, high-risk HIV-negative, or status unknown men who have sex with men (MSM; N = 65) were recruited from January 2016 to February 2017 and received (1) HST kits by mail, equipped with devices that detected when kits were opened and prompted a follow-up call from a counselor (eTEST); (2) standard HST kits with no follow-up (standard); or (3) informational letters about HIV testing locations (control) at baseline, 3 months, and 6 months...
September 2018: AIDS Patient Care and STDs
Zaake de Coninck, Laith Hussain-Alkhateeb, Göran Bratt, Anna Mia Ekström, Magnus Gisslén, Max Petzold, Veronica Svedhem
There is an ongoing debate whether the life span of successfully treated people living with HIV (PLHIV) is comparable with that of the general population. The aim of this cohort study is to compare all-cause mortality between all PLHIV, successfully treated PLHIV, and HIV-negative control persons from the general population and to explore the impact of viral load (VL) at diagnosis. A total of 4066 PLHIV were matched against 8072 HIV-negative controls according to age, sex, and region of birth. Further, associations between VL at diagnosis, time on treatment, treatment outcome, and mortality were assessed over a 15-year period...
August 2018: AIDS Patient Care and STDs
Natalie M Leblanc, Laura Albuja, Joseph DeSantis
In the context of HIV prevention, the provider-patient relationship has been found to profoundly impact HIV screening, patient initiation into HIV care, and adherence to medication following an HIV diagnosis. Given the importance of the provider-patient relationship, insight into provider approaches to cultivate such relationships is essential. Such insight could highlight considerations for provider engagement with patients that can address the current challenges in HIV prevention and treatment. This qualitative descriptive study sought to describe current health providers' approaches to engage patients into the HIV care continuum (HCC)...
August 2018: AIDS Patient Care and STDs
Leah M Adams, Benjamin Balderson, Bruce J Packett
Hepatitis C virus (HCV) is frequently comorbid with HIV infection and is independently associated with a significant increase in all-cause mortality among HIV-positive adults. HIV specialists' role and experiences in treating HCV has been understudied, especially among those providers who actively treat patients with HCV. We conducted a brief online survey of HIV specialists (physicians, nurse practitioners, physician assistants, and prescribing pharmacists) who treat patients with HCV to examine their experiences with treating these patients (HCV monoinfected, HIV/HCV coinfected)...
August 2018: AIDS Patient Care and STDs
Lara Coelho, Peter F Rebeiro, Jessica L Castilho, Yanink Caro-Veja, Fernando A Mejia, Carina Cesar, Claudia P Cortes, Denis Padgett, Catherine C McGowan, Valdiléa G Veloso, Timothy R Sterling, Beatriz Grinsztejn, Bryan E Shepherd, Paula M Luz
Early retention in care, sex, and sexual mode of HIV acquisition has been associated with mortality risk among persons living with HIV (PLWH). We assessed whether early retention in care mediates or modifies the association between mortality and sex and sexual mode of HIV acquisition among PLWH on antiretroviral therapy (ART) in the Americas. ART-naïve, adult PLWH (≥18 years) enrolling at Caribbean, Central and South America network for HIV epidemiology (CCASAnet) and Vanderbilt Comprehensive Care Clinic sites 2000-2015, starting ART, and with ≥1 visit after ART-start were included...
August 2018: AIDS Patient Care and STDs
Suzanne M Grieb, Molly Reddy, Brittany Griffin, Arik V Marcell, Sophie Meade, Becky Slogeris, Kathleen R Page, Jacky M Jennings
Sexually transmitted infection (STI) services, including screening, treatment, and counseling among youth, remain suboptimal. In the midst of increasing incidence of bacterial STIs, alarming STI disparities, and persistently low testing rates among youth, solution-focused and action-oriented research with youth is needed. To identify solutions to STI testing barriers, we conducted three participatory ideation workshops with 18 youth, 10 key stakeholders who work with youth, and 8 social design graduate students...
August 2018: AIDS Patient Care and STDs
Emma Sophia Kay, D Scott Batey, Michael J Mugavero
The Ryan White HIV/AIDS program (RWHAP) provides essential primary and supplementary health services to people living with HIV (PLWH). We examined the relationship between supplementary RWHAP services (Part B) and two outcomes: viral suppression (VS) and two separate measures of retention in care (RiC) based on kept- and missed-visits. We used purposive sampling to identify adult patients who received primary medical care at an academically-affiliated HIV/AIDS clinic in the southeastern United States (N = 1159) and who attended at least one scheduled HIV primary care appointment at the study site during 2015...
July 2018: AIDS Patient Care and STDs
Suzanne M McCluskey, Guinevere Q Lee, Kimia Kamelian, Annet Kembabazi, Nicholas Musinguzi, Mwebesa B Bwana, Conrad Muzoora, Jessica E Haberer, Peter W Hunt, Jeffrey N Martin, Yap Boum, David R Bangsberg, P Richard Harrigan, Mark J Siedner
The prevalence of HIV pretreatment drug resistance (PDR) is increasing in sub-Saharan Africa. We sought to describe correlates of PDR and evaluate effects of PDR on clinical outcomes in rural Uganda. We analyzed data from the Uganda AIDS Rural Treatment Outcomes study, a cohort of antiretroviral therapy (ART)-naive adults with HIV (2005-2015). We performed resistance testing on pre-ART specimens. We defined PDR as any World Health Organization (WHO) 2009 surveillance drug resistance mutation and classified PDR level using the Stanford algorithm...
July 2018: AIDS Patient Care and STDs
David J Brennan, Rusty Souleymanov, Nathan Lachowsky, Gerardo Betancourt, Daniel Pugh, Owen McEwen
The Internet is a common tool for gay, bisexual, and other men who have sex with men (MSM) to find sexual partners and sexual health information. Given persistently high human immunodeficiency virus (HIV) infection rates among MSM, it is important to examine the role of online outreach for MSM as part of HIV prevention and care. We provide an overview of the unique perspectives of online sexual health outreach, delivered through AIDS Service Organizations (ASOs) through sociosexual Internet sites and mobile applications...
July 2018: AIDS Patient Care and STDs
Maxine L Stitzer, Alexis S Hammond, Tim Matheson, James L Sorensen, Daniel J Feaster, Rui Duan, Lauren Gooden, Carlos Del Rio, Lisa R Metsch
This secondary analysis compares health behavior outcomes for two groups of HIV+ substance users randomized in a 3-arm trial [1] to receive Patient Navigation with (PN+CM) or without (PN) contingent financial incentives (CM). Mean age of participants was 45 years; the majority was male (67%), African American (78%), unemployed (35%), or disabled (50%). Behaviors incentivized for PN+CM were (1) attendance at HIV care visits and (2) verification of an active HIV medication prescription. Incentives were associated with shorter time to treatment initiation and higher rates of behaviors during the 6-month intervention with exception of month 6 HIV care visits...
July 2018: AIDS Patient Care and STDs
Joanne Simone, Mary Jo Hoyt, Deborah S Storm, Sarah Finocchario-Kessler
Preconception care can improve maternal and infant outcomes by identifying and modifying health risks before pregnancy and reducing unplanned pregnancies. However, information about how preconception care is provided to persons living with HIV (PLWH) is lacking. This study uses qualitative interviews with HIV care providers to describe current models of preconception care and explore factors influencing services. Single, anonymous, telephone interviews were conducted with 92 purposively selected HIV healthcare providers in Atlanta, Baltimore, Houston, Kansas City, Newark, Philadelphia, and San Francisco in 2013-2014...
July 2018: AIDS Patient Care and STDs
Ashley Murray, Sophia A Hussen, Lauren Toledo, LaTeshia Thomas-Seaton, Scott Gillespie, Chanda Graves, Rana Chakraborty, Madeline Y Sutton, Andres F Camacho-Gonzalez
HIV continuum of care analyses in Georgia during 2013 revealed that 82% of adolescents and adults living with HIV knew their diagnosis and that 75% were linked to care. However, of all persons in Georgia living with HIV in 2014, only 60% had at least one HIV care visit, and just 48% were retained in care. Understanding barriers for HIV testing, linkage, and retention in youth may strengthen HIV-related encounters and improve patient outcomes. We conducted 17 qualitative focus groups with HIV-positive and -negative youth, ages 18-24 years, from the Atlanta Metropolitan Statistical Area...
June 2018: AIDS Patient Care and STDs
Rebecca Dillingham, Karen Ingersoll, Tabor E Flickinger, Ava Lena Waldman, Marika Grabowski, Colleen Laurence, Erin Wispelwey, George Reynolds, Mark Conaway, Wendy F Cohn
Mobile health interventions may help People Living with HIV (PLWH) improve engagement in care. We designed and piloted PositiveLinks, a clinic-affiliated mobile intervention for PLWH, and assessed longitudinal impact on retention in care and viral suppression. The program was based at an academic Ryan White Clinic serving a nonurban population in Central Virginia. The PL intervention included a smartphone app that connected participants to clinic staff and provided educational resources, daily queries of stress, mood and medication adherence, weekly quizzes, appointment reminders, and a virtual support group...
June 2018: AIDS Patient Care and STDs
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