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Acta Tropica

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https://www.readbyqxmd.com/read/30321522/evaluation-of-a-short-term-effect-of-praziquantel-treatment-in-opisthorchiasis-induced-hepatobiliary-inflammation-by-urinary-8-oxodg
#1
Chompunoot Wangboon, Chanika Worasith, Raynoo Thanan, Chatanun Eamudomkarn, Anchalee Techasen, Jiraporn Sithithaworn, Watcharin Loilome, Nittaya Chamadol, Somchai Pinlaor, Amonrat Jumnainsong, Puangrat Yongvanit, Narong Khuntikeo, Jeffrey M Bethony, Paiboon Sithithaworn
Inflammation of the hepatobiliary system in chronic opisthorchiasis is associated with an elevated level of urinary 8-oxo-7,8 dihydro-2'deoxyguanosine (8-oxodG) during active as well as past exposure to Opisthorchis viverrini infection. In this study, we evaluated the short-term effect of praziquantel treatment on hepatobiliary disease (HBD) using urinary 8-oxodG as an inflammatory marker in a cohort of residents in endemic areas of opisthorchiasis in Khon Kaen, Thailand. The HBD status in terms of periductal fibrosis (PDF) was determined by abdominal ultrasonography and O...
October 12, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30321521/identification-of-a-previously-unidentified-endemic-region-for-taeniasis-in-north-sumatra-indonesia
#2
Umar Zein, Sahat Siregar, Indra Janis, Abdul Harris Pane, Jan Maurisdo Purba, Teguh Wahyu Sardjono, Toni Wandra, Kadek Swastika, Hadyanto Lim, Tetsuya Yanagida, Munehiro Okamoto, Akira Ito
In North Sumatra, Indonesia, taeniasis has previously been reported solely from Samosir Island located in Lake Toba. In 2014, however, three individuals were identified with taeniasis after voluntarily reporting for treatment, stimulating a subsequent investigation conducted in 2017. This investigation indicated that a previously unidentified endemic area exists in Simalungun District. Molecular analysis showed the worms to be hybrid-derived descendants of Taenia asiatica and Taenia saginata, which is consistent with specimens identified previously from Samosir Island...
October 12, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30308208/in-silico-modeling-of-plasmodium-falciparum-chloroquine-resistance-transporter-protein-and-biochemical-studies-suggest-its-key-contribution-to-chloroquine-resistance
#3
Hiasindh Ashmi Antony, Nishith Saurav Topno, Sathyanarayana N Gummadi, Devanarayanan Siva Sankar, Ramadas Krishna, Subhash Chandra Parija
Chloroquine (CQ) has been used for decades as the primary chemotherapeutic drug for the treatment of malaria. The emergence of drug resistance in Plasmodium falciparum has been considered to be because of the excessive use of antimalarial drugs worldwide. Moreover, the intense distribution and prevalence of chloroquine-resistant strains in endemic regions has aided the incidence of more complications to malaria treatment and control. Due to the lack of literature that portrays evident molecular mechanisms of drug resistance, it has been difficult to understand the drug resistance conferred by Plasmodium species...
October 9, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30308207/brucellosis-seroprevalence-in-dairy-cattle-in-china-during-2008-2018-a-systematic-review-and-meta-analysis
#4
Xuhua Ran, Jiajia Cheng, Miaomiao Wang, Xiaohong Chen, Haoxian Wang, Yu Ge, Hongbo Ni, Xiao-Xuan Zhang, Xiaobo Wen
Brucellosis remains one of the most common zoonotic diseases globally with more than a half million human cases reported annually. The Brucella reservoir associated with livestock brucellosis poses a significant threat to public health, and awareness of the seroprevalence and spatial distribution of livestock brucellosis is valuable for the prevention and control of diseases caused by Brucella, especially human brucellosis. Therefore, we conducted a systematic review and meta-analysis to evaluate the seroprevalence of brucellosis in dairy cattle in China...
October 8, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30292751/risk-analysis-and-seroprevalence-of-hev-in-people-living-with-hiv-aids-in-brazil
#5
Luan Araújo Bezerra, Edmilson Ferreira de Oliveira-Filho, José Valter Joaquim Silva, Viviane Martha Santos Morais, Juliana Prado Gonçales, Dayvson Mauricio da Silva, Maria Rosângela Cunha Duarte Coêlho
Acute Hepatitis E virus (HEV) infection in people living with HIV/AIDS (PLHA) can lead to fulminant hepatic failure, cirrhosis and death. The prevalence of anti-HEV antibodies within this group varies according to the geographical area. However, in South America, studies concerning the detection of HEV in PLHA are rare. Here, we investigated the presence of HEV by serological and molecular detection and evaluated the risk factors associated with infection in PLHA in Pernambuco state, Brazilian Northeast. Serological and molecular detection of HEV was performed in 366 samples of PLHA by ELISA for anti-HEV IgG and RT-PCR, respectively...
October 4, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30290285/parasitaemia-and-parasitic-load-are-limited-targets-of-the-aetiological-treatment-to-control-the-progression-of-cardiac-fibrosis-and-chronic-cardiomyopathy-in-trypanosoma-cruzi-infected-dogs
#6
Ivo Santana Caldas, Ana Paula de Jesus Menezes, Lívia de Figueiredo Diniz, Álvaro Fernando da Silva do Nascimento, Rômulo Dias Novaes, Sérgio Caldas, Maria Terezinha Bahia
It is still unclear whether the progression of acute to chronic Chagas cardiomyopathy is predominantly associated with the limited efficacy of aetiological chemotherapy, or with the pharmacological resistance profiles and pathogenicity of specific Trypanosoma cruzi strains. Thus, we tested the hypothesis that parasitic load could be a limited target of aetiological chemotherapy to prevent chronic cardiomyopathy in dogs infected by different T. cruzi strains. Animals were infected with benznidazole-susceptible (Berenice-78) and -resistant (VL-10 and AAS) strains of T...
October 2, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30287252/enhanced-mortality-in-deltamethrin-resistant-aedes-aegypti-in-thailand-using-a-piperonyl-butoxide-synergist
#7
Monthathip Kongmee, Kanutcharee Thanispong, Sunaiyana Sathantriphop, Chutipong Sukkanon, Michael J Bangs, Theeraphap Chareonviriyaphap
Aedes aegypti is the primary vector of dengue viruses in Thailand. Control of this mosquito continues to rely heavily on use of insecticides in various forms and applications. The synergistic effect of piperonyl butoxide (PBO), combined with deltamethrin against eight populations of Ae. aegypti collected from different regions in Thailand is presented. The standard WHO adult contact bioassays found all populations with low to moderate levels of resistance to deltamethrin alone (using a 0.05% discriminating concentration), with final mortalities ranging from 15...
October 1, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30282003/seasonal-and-spatial-distribution-of-aedes-aegypti-and-aedes-albopictus-in-a-municipal-urban-park-in-s%C3%A3-o-paulo-sp-brazil
#8
Marta Ribeiro Heinisch E Silva, Fredi Alexander Diaz-Quijano, Francisco Chiaravalloti-Neto, Filipe Gabriel Menezes Pancetti, Ronan Rocha Coelho, Pâmela Dos Santos Andrade, Paulo Roberto Urbinatti, Rosa Maria Marques Sá de Almeida, Tamara Nunes de Lima-Camara
Dengue, yellow fever, chikungunya and Zika are important arboviruses present in various countries of the world, the etiological agents of which are transmitted to human-beings by the bite of infected females of Aedes aegypti and Aedes albopictus. Biological aspects of these vectors, such as their distribution and abundance, are influenced by climatic variables such as rainfall and temperature. We assess the spatial and seasonal distribution of Ae. aegypti and Ae. albopictus, during spring 2014 and spring 2015 and autumn 2015 and autumn 2016, in an urban Municipal Park, São Paulo (SP, Brazil), using 36 ovitraps...
September 30, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30278154/molecular-characterization-of-human-echinococcosis-in-sichuan-western-china
#9
Shang Jingye, Zhang Guangjia, Yu Wenjie, He Wei, Wang Qian, Zhong Bo, Wang Qi, Liao Sha, Li Ruirui, Chen Fan, Huang Yan
Cystic echinococcosis (CE) and alveolar echinococcosis (AE) are highly co-endemic in Sichuan, a part of Qinghai-Tibet Plateau where is a typical Tibetan nomadic community living area. In order to better understand the Echinococcus spp. of human being infected origins in this area, 140 lesions were collected from echinococcosis patients who were received operations during the period of 2014-2016 in different geographic districts in this region. Partial DNA sequences of the mitochondrial cox1 gene were analyzed...
September 29, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30273563/echinostoma-revolutum-development-of-a-high-performance-dna-specific-primer-to-demonstrate-the-epidemiological-situations-of-their-intermediate-hosts
#10
Sothorn Anucherngchai, Thapana Chontananarth
Echinostomiasis caused by the Echinostoma group, in particular E. revolutum are a significant problem for both humans and other animals. This group has a large number of morphological similarities that are difficult and time-consuming to identify. The present study aimed to develop high-performance tools for the detection of the prevalence of E. revolutum and to reveal the prevalence of E. revolutum infections in intermediate snail hosts in Lopburi province, Thailand. The snail specimens were collected by stratified sampling method and examined to collect trematodes in the larval stage...
September 28, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30273562/gene-expression-profile-of-cytokines-produced-in-biopsies-from-patients-with-american-cutaneous-leishmaniasis
#11
Daise Damaris Carnietto de Hippólito, Aparecida Helena Souza Gomes, Marta Marques Maia, Cristina da Silva Meira-Strejevitch, Cristina Takami Kanamura, José Angelo Lauletta Lindoso, Vera Lucia Pereira-Chioccola
American cutaneous leishmaniasis (ACL) causes a local inflammatory process, inducing expression of several cytokine genes. Particularly, IFN-γ can predict to disease susceptibility. Based in these data, this study was aimed to investigate the gene expression profile of IFN-γ, IL-10, IL-27, TNF-γ, TGF-β and IL-6 produced in biopsies from ACL patients; and whether the gene expression profile of IFN-γ could determine the disease evolution. Gene expression of 6 cytokines was investigated in 40 formalin-fixed paraffin embedded (FFPE) biopsies from patients with cutaneous leishmaniosis (CL); and 10 FFPE biopsies from patients with mucosal leishmaniasis (ML) (control)...
September 28, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30268686/snake-venom-proteome-and-immuno-profiling-of-the-hundred-pace-viper-deinagkistrodon-acutus-in-taiwan
#12
Po-Chuan Chen, Ming-Nan Huang, Jia-Feng Chang, Chien-Chun Liu, Chun-Kuei Chen, Cheng-Hsien Hsieh
DEINAGKISTRODON ACUTUS: also known as the hundred-pace viper or Chinese moccasin, is a clinically significant venomous snake in Taiwan. To address the lack of knowledge on the venom proteome of D. acutus, the venom composition was studied by a bottom-up proteomic approach combining reverse phase high-performance liquid chromatography, SDS-PAGE, and LC-MS/MS analysis. The immunoreactivity and cross-reactivity of Taiwanese freeze-dried D. acutus antivenom (DA-AV) and hemorrhagic antivenom (FH-AV) were investigated, as well...
September 27, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30268685/knowledge-attitude-and-practices-relating-to-zoonotic-diseases-among-livestock-farmers-in-punjab-india
#13
B B Singh, R Kaur, G S Gill, J P S Gill, R K Soni, R S Aulakh
Zoonotic diseases cause significant health and economic impact in developing countries such as India. Many zoonotic diseases are prevalent in the livestock and as an occupational zoonosis in the livestock farmers in India. Lack of knowledge on the disease transmission, prevention and control measures is a potential high risk for the occurrence of zoonotic diseases in the livestock and its keepers in India. We conducted this study to understand knowledge, attitude and practices of livestock farmers regarding zoonoses...
September 27, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30267659/prevalence-of-antibodies-against-toxoplasma-gondii-and-neospora-spp-in-equids-of-western-par%C3%A3-brazil
#14
Thiago Rocha Moreira, Cristiane Sarturi, Felipe Nascimento Stelmachtchuk, Emelie Andersson, Emma Norlander, Francisco Leonardo Costa de Oliveira, Juliana Machado Portela, Arlei Marcili, Ulf Emanuelson, Solange Maria Gennari, Antonio Humberto Hamad Minervino
The present study aimed to determine the prevalence of antibodies against Toxoplasma gondii and Neospora spp. in equids raised for distinct purposes in the western state of Pará, Brazil, and to identify potential risk factors associated with parasite infection. A cross-sectional study was conducted with cluster sampling in 101 farms from 18 municipalities (farm horses). In visited municipalities, samples from sport and cart horses were included. Serum was obtained for detecting antibodies against T. gondii and Neospora spp...
September 27, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30267658/progress-towards-international-adoption-of-the-world-health-organization-ultrasound-classification-of-cystic-echinococcosis
#15
E Mirabile, N Solomon, P J Fields, C N L Macpherson
Cystic echinococcosis (CE) is a global parasitic zoonosis for which ultrasound (US) is the gold standard modality for diagnosis. In 2003, the WHO published a standardized US classification of CE, on which WHO treatment guidelines are based. In 2014, global adoption of the classification was questioned by a publication which indicated that, between 2004 and 2014, only half of studies utilizing a classification used the WHO classification. More recent studies have demonstrated that the WHO classification best reflects the natural history of CE, and is used with high reliability by experts in the field; despite these attributes, the classification's impact is ultimately limited by the extent of its adoption...
September 27, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30261187/seroprevalence-of-bluetongue-virus-in-small-and-large-ruminants-in-punjab-province-pakistan
#16
Tayyebah Sohail, Tahir Yaqub, Tariq Abbas, Masood Rabbani, Jawad Nazir, Syeda Marriam Maqbool, Saima Yaqub, Momena Habib, Aziz Ul-Rahman, Nadia Mukhtar, Muhammad Shahbaz, Muhammad Yasir Zahoor, Muhammad Zubair Shabbir
Bluetongue (BT) is a vector-borne disease of immense economic importance for small and large ruminants. Despite frequent disease reports from neighboring countries, a little is known about current disease status and prevalent serotypes in Pakistan. We screened a total of 1312 healthy animals for group-specific antibodies and serotype-specific genome for BT virus through competitive ELISA and real-time PCR, respectively. An overall prevalence of group-specific VP7 antibodies [28.81% (n = 378/1312, 95% CI = 26...
September 24, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30261186/schistosomes-snails-and-climate-change-current-trends-and-future-expectations
#17
REVIEW
Anna-Sofie Stensgaard, Penelope Vounatsou, Mita E Sengupta, Jürg Utzinger
The exact impact of climate change on schistosomiasis, a blood-fluke affecting more than 250 million people mainly in tropical and subtropical countries, is currently unknown, but likely to vary with the snail-parasite species' specific ecologies and the spatio-temporal scale of investigation. Here, by means of a systematic review to identify studies reporting on impacts of climate change on the agents of schistosomiasis, we provide an updated synthesis of the current knowledge about the climate change-schistosomiasis relation...
September 24, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30248316/a-new-species-of-maritrema-trematoda-microphallidae-parasitizing-the-baird-s-sandpiper-calidris-bairdii-and-comments-about-diversity-of-microphallidae-in-two-nearctic-shorebirds-at-patagonian-sites-in-argentina
#18
Sofia Capasso, Verónica L D'Amico, Julia I Diaz
Birds are hosts of a wide diversity of trematodes. Between them, the Microphallidae is a common family with a cosmopolitan distribution. Nevertheless, only 10 Maritrema species have been recorded previously in South America. The aim of the present paper is to describe a new species of Maritrema parasitizing the Nearctic Baird's sandpiper, Calidris bairdii in its wintering areas in Patagonia, Argentina. We also analyze and compare the microphallid diversity in two host species. We collected 44 C. bairdii and 50 Calidris fuscicollis in search of helminths...
September 22, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30248315/mitochondrial-genome-of-paruterina-candelabraria-cestoda-paruterinidae-with-implications-for-the-relationships-between-the-genera-cladotaenia-and-paruterina
#19
Aijiang Guo, Li Wang, Shaohua Zhang, Yadong Zheng, Boyko B Georgiev, Xuenong Luo, Siyang Huang, Xuepeng Cai
The taxonomic concept for the family Paruterinidae is controversial, especially concerning the position of the genus Cladotaenia, since the latter genus has been placed sometimes in other families, i.e. in the Taeniidae or in the distinct family Cladotaeniidae; finding a solution based on morphological data is difficult and molecular data on paruterinids and related groups are scarce. In this study, the complete mitochondrial (mt) genome sequence of the type-species of the type-genus of the Paruterinidae, Paruterina candelabraria, was determined and annotated...
September 21, 2018: Acta Tropica
https://www.readbyqxmd.com/read/30244133/seroprevalence-of-dengue-fever-and-the-associated-sociodemographic-clinical-and-environmental-factors-in-makkah-madinah-jeddah-and-jizan-kingdom-of-saudi-arabia
#20
Rajaa Al-Raddadi, Osama Alwafi, Omima Shabouni, Naeema Akbar, Mohammed Alkhalawi, Adel Ibrahim, Raheela Hussain, Mohammed Alzahrani, Mohammed Al Helal, Abdullah Assiri
This study aimed to estimate the seroprevalence of anti-dengue IgG antibodies in Makkah, Al Madinah, Jeddah, and Jizan; and to identify the associated demographic, clinical, and environmental independent risk factors. A community-based household serosurvey conducted between September 20, 2016 and January 31, 2017. A multi-stage stratified cluster sampling was used to select 6596 participants from Makkah, Madinah, Jeddah, and Jizan. Blood samples were drawn from all participants to detect anti-dengue IgG antibodies...
September 20, 2018: Acta Tropica
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