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Acta Paediatrica

Anna C van der Vossen, Linda Al-Hassany, Sandra Buljac, Jan-Dietert Brugma, Arnold G Vulto, Lidwien M Hanff
AIM: Due to a lack of age-appropriate formulations, administration of drugs to children remains a challenge. This study aimed to identify the problems experienced in both the outpatient setting, as well as the clinical setting. METHODS: Between June 2017 and January 2018, we performed a cross-sectional, prospective study at the Sophia Children's Hospital, The Netherlands. The study comprised of a structured interview on drug manipulations with parents visiting the outpatient clinic, and an observational study of drug manipulations by nurses at the wards...
January 11, 2019: Acta Paediatrica
Gill Nilsson, Joakim Westerlund, Elisabeth Fernell, Eva Billstedt, Carmela Miniscalco, Thomas Arvidsson, Ingrid Olsson, Christopher Gillberg
AIM: Clinical developmental phenotyping of 4- to 5-year-old children with febrile seizures (FS). METHODS: Children with FS (n=157, corresponding to 3.7% of the targeted general population of 4-5-year-olds), had been identified at Child Healthcare Centres in Gothenburg. Parents of 73 children (41 boys, 32 girls) accepted participation in the present study. The assessments included a neuropaediatric assessment, Movement ABC, Wechsler Preschool and Primary Scale of Intelligence-III and parent questionnaires (Five-to-Fifteen (FTF) and Strengths and Difficulties Questionnaire (SDQ))...
January 7, 2019: Acta Paediatrica
Ruth Sinclair, Barbara Bajuk, Robert Guaran, Daniel Challis, Joanne Sheils, Mohamed E Abdel-Latif, Lisa Hilder, Ian M Wright, Ju Lee Oei
AIM: To determine the relationship between clinical practice and publication of an Australian consensus statement for management of extremely preterm infants published in 2006. METHODS: A population based study using linked data from New South Wales, Australia for births between 22+0 and 26+6 weeks of gestation between 2000 and 2011. RESULTS: There were 4,746 births of whom 2,870 were liveborn and 1,876 were stillborn. Of the live births, 2,041(71%) were resuscitated, 1,914 (67%) were admitted into a neonatal intensive care unit (NICU) and 1,310 (46%) survived to hospital discharge...
January 7, 2019: Acta Paediatrica
Kanwaljeet J S Anand, Joseph Rigdon, Cynthia R Rovnaghi, FeiFei Qin, Sahil Tembulkar, Nicole Bush, Kaja LeWinn, Frances A Tylavsky, Robert Davis, Donald A Barr, Ian H Gotlib
AIM: Early life adversity in leads to enduring effects on physical and mental health, school performance, and other outcomes. We sought to identify potentially modifiable factors leading to socioeconomic adversity in early life. METHODS: We enrolled 1,503 pregnant women aged 16-40 years, without pregnancy complications or pre-existing conditions from Shelby County, Tennessee. Social, familial, and economic variables were analyzed using principal components (PCs) analyses to generate the Socioeconomic Adversity Index (SAI)...
January 7, 2019: Acta Paediatrica
Matti Korppi, Minna Mecklin, Paula Heikkilä
AIM: Meta-analyses of randomised controlled trials on infant bronchiolitis do not support medication. We summarised the current data and evaluated the real-life use of medication for infants treated for bronchiolitis in hospitals, including paediatric wards, emergency departments and paediatric intensive care units (PICU). METHODS: We searched PubMed for studies published from 2009-2018 that provided data on the real-life use of adrenaline, salbutamol, corticosteroids or antibiotics for infants hospitalised for bronchiolitis...
January 7, 2019: Acta Paediatrica
Vania Sandoz, Myriam Bickle-Graz, Valérie Camos, Antje Horsch
Postpartum depression (PPD) and posttraumatic stress disorder (PTSD) may develop after preterm birth, with prevalence rates of 17% and 24% for PPD and PTSD, respectively. Children of mothers with PPD or PTSD are more likely to have adverse developmental outcomes, particularly with regards to their emotion regulation. Emotion regulation allows control over the intensity, duration, and expression of emotions. This represents an important aspect of child development, as well as a cornerstone of future personal and professional life...
December 27, 2018: Acta Paediatrica
Elin Lööf, Hanneke Andriesse, Eva Broström, Marie André, Stephanie Böhm, Sven Bölte
AIM: To study health-related quality of life (HRQoL) in children with idiopathic clubfoot and the influence of sex, clubfoot laterality and neurodevelopmental difficulties on HRQoL. METHODS: A cross-sectional questionnaire-based study in Stockholm and Skåne Counties, Sweden, of 106 children with idiopathic clubfoot born 2004 to 2007 (mean 9.4 ±0.6 years) and a general population sample of 109 schoolchildren (mean 9.5 ±0.6 years). The children and their caregivers answered the EQ-5D-Y (Youth) and Five to Fifteen questionnaires to operationalise HRQoL and neurodevelopmental difficulties, respectively...
December 27, 2018: Acta Paediatrica
Lars Walløe, Nils Lid Hjort, Marianne Thoresen
No abstract is available for this article. This article is protected by copyright. All rights reserved.
December 27, 2018: Acta Paediatrica
Lucia Calthorpe, Soren Brage, Ken K Ong
AIM: To systematically appraise and summarise published evidence on the association between childhood physical activity and subsequent age at menarche. METHODS: We searched PubMed (1990-2018) for studies that reported the relationship between childhood physical activity and age at menarche. We performed tabular synthesis of population-based studies and a random-effects meta-analysis of results of athlete/non-athlete studies. RESULTS: One randomised controlled trial was identified, in which an intervention to prevent obesity reduced the likelihood of menarche during the two-year study period (relative risk: 0...
December 27, 2018: Acta Paediatrica
Manuela Filippa
No abstract text is available yet for this article.
December 25, 2018: Acta Paediatrica
Islam Nour, Hesham Abdel-Hady
No abstract text is available yet for this article.
December 25, 2018: Acta Paediatrica
Shyam Sundar Budhathoki, Rejina Gurung, Uwe Ewald, Jeevan Thapa, Ashish Kc
AIM: This paper examines the change in neonatal resuscitation practices after the implementation of the Helping Babies Breathe (HBB) program. METHODS: A systematic review was carried out on studies reporting the impact of HBB programs among the literature found in Medline, POPLINE, LILACS, African Index Medicus, Cochrane, Web of Science, and Index Medicus for the Eastern Mediterranean Region database. We selected clinical trials with randomized control, quasi-experimental and cross-sectional designs...
December 24, 2018: Acta Paediatrica
J Larsson Viksten, L Engerström, I Steinvall, A Samuelsson, M Fredrikson, S Walther, F Sjöberg
AIM: This study described the basic characteristics of children aged 0-16 years who were treated in intensive care units (ICUs) and paediatric ICUs (PICUs), compared their outcomes and examined any causes of death. METHODS: This was a retrospective cohort study of admissions to 74 ICUs and three PICUs in Sweden that were recorded in the Swedish Intensive Care Registry from 1 January 2008 to 31 December 2012. RESULTS: We retrieved data on 12,756 children who were admitted 17,003 times...
December 24, 2018: Acta Paediatrica
Matti Korppi
AIM: In 2017, the European Respiratory Society task force stated that protracted bacterial bronchitis (PBB) was a distinct clinical entity and outlined the diagnostic criteria and principles for treatment. However, this guidance was based on data from Australia and the USA. This mini review evaluated the data and addressed the lack of researched-based data from Europe. METHODS: We supplemented the 2017 report by conducting a non-systematic review of the literature on prolonged wet or productive cough and on PBB in children up to September 2018...
December 23, 2018: Acta Paediatrica
Jan Gustafsson
No abstract text is available yet for this article.
December 21, 2018: Acta Paediatrica
Nandkishor S Kabra
No abstract text is available yet for this article.
December 21, 2018: Acta Paediatrica
Anna-Lena Hård, Anders K Nilsson, Anna-My Lund, Ingrid Hansen-Pupp, Lois E H Smith, Ann Hellström
AIM: This non-systematic review examined differences in the composition of raw maternal breast milk and pasteurised donor milk and possible health effects on preterm infants. METHODS: We searched PubMed up to July 2018 for studies published in English that focused on four comparisons: raw maternal milk versus donor milk, human milk before and after Holder pasteurisation, milk from mothers who delivered preterm and at term and milk collected during early and late lactation...
December 18, 2018: Acta Paediatrica
Maria Hafström, Øyvind Salvesen, Ingemar Kjellmer
AIM: To evaluate sex differences in infants born at term with metabolic acidosis with regard to perinatal health and symptomatology, and developmental outcome. METHODS: From a population-based cohort of infants born at term (n=14,687) 78 were prospectively identified as having metabolic acidosis at birth. Two matched controls per case were selected. Sex differences in perinatal characteristics and in neurodevelopmental outcome at 6.5 years of age were analyzed. Subgroup analysis were made based on need of neonatal care and planned follow-up...
December 18, 2018: Acta Paediatrica
I Tiberg, H Hansson, I Hallström, A Carlsson
AIM: This paper presents an implementation study following previous research including a randomised controlled trial (RCT) of hospital-based home care (HBHC), referring to specialist care in a home-based setting. The aim was to evaluate whether the effects sustained when rolled out into wider practice. METHODS: In 2013-2014, 42 children newly diagnosed type 1 diabetes were included in the study at a university hospital in Sweden and followed for two years. Measurements of child safety, effects of services, resource use and service quality was included...
December 18, 2018: Acta Paediatrica
Poul-Erik Kofoed, Marianne Toft Madsen, Jane Thomsen
Missed hospital appointments increase health costs, make the healthcare systems less effective and can delay diagnoses and treatments. Studies have shown that providing reminders by letter, texts or telephone calls decreased non-attendance rates. The paediatric outpatient clinic at Kolding Hospital, Denmark, experienced an increasing number of late cancellations and no-shows, despite sending automated texts 48 hours before appointments. We decided to call parents two weeks before their child's appointment to encourage them to cancel if they were unable to attend or no longer needed the consultation...
December 18, 2018: Acta Paediatrica
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