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Acta Paediatrica

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https://www.readbyqxmd.com/read/28328065/randomised-controlled-trial-demonstrates-that-fermented-infant-formula-with-short-chain-galacto-oligosaccharides-and-long-chain-fructo-oligosaccharides-reduces-the-incidence-of-infantile-colic
#1
Yvan Vandenplas, Thomas Ludwig, Hetty Bouritius, Philippe Alliet, Derek Forde, Stefaan Peeters, Frederic Huet, Jonathan Hourihane
AIM: We examined the effects on gastrointestinal tolerance of a novel infant formula that combined specific fermented formula (FERM) with short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides (scGOS/lcFOS), with a 9:1 ratio and concentration of 0.8g/100ml. METHODS: This prospective, double-blind, randomised, controlled trial comprised 432 healthy, term infants aged 0-28 days whose parents decided to not start, or discontinued,, breastfeeding...
March 22, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28326623/neurophysiological-assessment-of-acute-pain-in-infants-a-scoping-review-of-research-methods
#2
REVIEW
B Benoit, R Martin-Misener, A Newman, M Latimer, M Campbell-Yeo
A systematic scoping search to describe the neurophysiological methods used in infant acute pain assessment research was conducted. Of the 2411 abstracts screened, 19 articles were retained. Nine studies utilized near infrared spectroscopy (NIRS), two utilized functional magnetic resonance imaging (fMRI), and eight utilized electroencephalography (EEG). There was methodological variability in studies utilizing NIRS, whereas EEG and fMRI studies reported consistent methods. Of the eight EEG studies, six identified a nociceptive specific event-related potential...
March 22, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28321913/heart-rate-variability-can-be-used-to-evaluate-wellbeing-in-preterm-infants
#3
K Kaar, J Brandner, B Minnich, J Hilberath, C Weisser, M Wald
Preterm infants are exposed to various potentially stressful procedures during intensive care, which have been shown to compromise development. We explored the potential stress caused by echocardiograph and the correlation between the duration of the investigation and the amplitude of the alteration. The usefulness of the Newborn Infant Parasympathetic Evaluation (NIPE) monitor (Mdoloris Medical Systems, Loos, France) for assessing acute distress during daily routines, based on heart rate variability, was also investigated...
March 21, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28321911/the-increasing-consumption-of-unprescribed-antibiotics-by-greek-preschool-children-amounts-to-unacceptable-malpractice
#4
Fotini Andritsou, Vassiliki Benetou, Koralia A Michail, Nikolaos Pantazis, Ioanna D Pavlopoulou
In Greece, the illegal dispensing of prescription-only medicines, including antibiotics, by pharmacies without the necessary medical prescription, remains standard practice (1,2). This has continued, despite the fact that the country has the highest rates of antibiotic consumption, both in hospitals and the community, as well as antibiotic resistance, compared to other European countries (3). The frequency of antibiotic administration without a prescription, and the factors associated with this practice, was evaluated in a sample of preschool children under the age of six years (range 10-65 months) in the Municipality of Athens, Greece...
March 21, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28321910/the-coming-of-age-of-a-young-subspecialty-paediatric-hepatology
#5
REVIEW
Antal Németh
Paediatric hepatology dates from the 1970s and it is the youngest of the organ-specific subspecialties. Since then there have been impressive achievements in the fields of anatomical, metabolic, immunological and neoplastic diseases and the advent of modern molecular biology has resulted in a marked increase in exact diagnoses. Liver transplants provided enormous stimulus for the discipline. Due to changing morbidity patterns the discipline faces new challenges, such as environmental and lifestyle induced liver diseases, but different forms of chronic viral hepatitis are diminishing...
March 21, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28316118/late-preterm-birth-has-direct-and-indirect-effects-on-infant-gut-microbiota-development-during-the-first-six-months-of-life
#6
M Forsgren, E Isolauri, S Salminen, S Rautava
AIM: Preterm infants display aberrant gut microbial colonisation. We investigated whether the differences in gut microbiota between late preterm and full-term infants results from prematurity or external exposures. METHODS: This study comprised 43 late preterm infants (34(0/7) - 36(6/7) ) and 75 full-term infants based on faecal samples collected following birth and at two to four weeks and six months of age. We assessed clinically relevant bacteria using quantitative polymerase chain reaction...
March 17, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28316105/hypoxaemia-and-septic-shock-were-independent-risk-factors-for-mechanical-ventilation-in-bangladeshi-children-hospitalised-for-diarrhoea
#7
Mohammod Jobayer Chisti, K M Shahunja, Farzana Afroze, Abu Smsb Shahid, Sharifuzzaman, Tahmeed Ahmed
AIM: In Bangladesh approximately 6% of children under five years of age die due to diarrhoea. We evaluated the admission and hospitalisation risk factors for mechanical ventilation and outcomes in children with diarrhoea. METHODS: This retrospective case-control chart analysis was conducted in the intensive care unit of Dhaka Hospital of International Centre for Diarrhoeal Disease Research, Bangladesh. We enrolled 219 children with diarrhoea aged 0-59 months between August 2009 and July 2013...
March 17, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28316098/therapeutic-options-for-dysfunctional-breathing-in-children-and-adolescents
#8
Bodo Niggemann, Christine Lehmann, Dorothea Pfeiffer-Kascha, Christa Weiss
Dysfunctional breathing is common and represents important differential diagnoses for respiratory discomfort. Typical examples include habit cough, sighing dyspnoea, hyperventilation syndrome, dysfunctional breathing patterns or vocal cord dysfunction (1,2). Comorbidities are frequent, especially with bronchial asthma. In some cases dysfunctional breathing may be a sequelae of child neglect or abuse. This article is protected by copyright. All rights reserved.
March 17, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28316097/improved-postnatal-care-is-needed-to-maintain-gains-in-neonatal-survival-after-the-implementation-of-the-helping-babies-breathe-initiative
#9
J Wrammert, A Kc, U Ewald, M Målqvist
AIM: Helping Babies Breathe (HBB) is a neonatal resuscitation protocol proven to reduce intrapartum-related mortality in low-income settings. The aim of this study was to describe the timing and causes of neonatal in-hospital deaths before and after HBB training at a maternity health facility in Nepal. METHODS: A prospective cohort study was conducted at the facility between July 2012 and September 2013. All 137 staff, including medical doctors and midwives, were trained in January 2013...
March 17, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28301061/the-sbu-report-a-different-view
#10
Alex V Levin
The paper by Lynøe and coworkers(1) is a summary of the previously published SBU report of 2016 (2) in which the authors correctly state, "The injuries in question in situations in which traumatic shaking is suspected may be serious in nature, both in acute terms and also in the longer term. The injuries may be life-threatening, or entail a risk of permanent consequences in terms of the child's development, health and future quality of life." This article is protected by copyright. All rights reserved.
March 16, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28295538/authorised-access-web-portal-for-italiandata-bank-on-sudden-unexpected-perinatal-and-infant-death
#11
Giulia Ottaviani, Paolo Perlasca, Marco Mesiti, Luca Ferrari, Anna M Lavezzi
Sudden infant death syndrome (SIDS) is common during the first year of life and affects 0.40every 1,000 births (1). Stillbirths are seven times more common than SIDS; in 40-80% of cases remain unexplained and are categorised as sudden intrauterine unexpected death syndrome (2).In 2006 Italy passed legislation that fetuses, and infants, from 25 weeks of gestation to one postnatal year, that died suddenly and unexpectedly should be sent to the University of Milan, Italy, for an in-depth diagnostic post-mortem with parental permission (3)...
March 15, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28295623/auditory-impairment-in-infants-with-neonatal-chronic-lung-disease-is-alleviated-after-term
#12
Ze D Jiang
AIM: Very premature infants with neonatal chronic lung disease (CLD) have been reported to have major auditory impairment at term and we examined the outcomes in 30 infants after term age. METHODS: Brainstem auditory evoked response (BAER) was recorded at a postconceptional age of 46-61 weeks in 13 CLD cases and 14 controls from China and 17 CLD cases and 22 controls from the UK. RESULTS: The BAER threshold in the CLD infants was slightly higher...
March 12, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28295602/child-survival-revolutions-revisited-lessons-learned-from-bangladesh-nicaragua-rwanda-and-vietnam
#13
REVIEW
Lars Åke Persson, Anisur Rahman, Rodolfo Peña, Wilton Perez, Aimable Musafili, Dinh Phuong Hoa
Analysing child mortality may enhance our perspective on global achievements in child survival. We used data from surveillance sites in Bangladesh, Nicaragua and Vietnam and Demographic Health Surveys in Rwanda to explore the development of neonatal and under-five mortality. The mortality curves showed dramatic reductions over time, but child mortality in the four countries peaked during wars and catastrophes and was rapidly reduced by targeted interventions, multi-sectorial development efforts and community engagement CONCLUSION: Lessons learned from these countries may be useful when tackling future challenges, including persistent neonatal deaths, survival inequalities and the consequences of climate change and migration...
March 12, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28295585/systematic-review-of-non-pharmacological-analgesic-interventions-for-common-needle-related-procedure-in-newborn-infants-and-development-of-evidence-based-clinical-guidelines
#14
REVIEW
P Lago, E Garetti, C V Bellieni, D Merazzi, P Savant Levet, G Ancora, A Pirelli
The aim of this literature review was to develop clinical guidelines for the prevention and control of needle-related pain in newborn infants. The guidelines were developed by the Italian Society of Neonatology, using the Grading of Recommendations, Assessment, Development and Evaluation approach, based on the assessment of 232 papers published between 1986 and 2015. The quality of the evidence was high or moderate for some behavioural and non-pharmacological interventions. CONCLUSION: There was sufficient evidence to strongly support the use of non-pharmacological interventions for common needle-related procedures in newborn infants...
March 12, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28295577/higher-growth-fat-and-fat-free-masses-correlate-with-larger-cerebellar-volumes-in-preterm-infants-at-term
#15
Giulia Paviotti, Angela De Cunto, Floriana Zennaro, Giulia Boz, Laura Travan, Gabriele Cont, Jenny Bua, Sergio Demarini
AIM: Smaller cerebellar volumes in very low birth weight (VLBW) infants at term have been related to adverse cognitive outcomes and this study evaluated whether these volumes were associated with a growth in body composition during hospital stays. METHODS: We prospectively recruited 42 VLBW infants from an Italian neonatal unit between January 2013 and August 2015. Cerebellar volumes and body composition were measured by magnetic resonance imaging (MRI) and air-displacement plethysmography, respectively, at 40 weeks of gestational age and anthropometric and nutritional data were collected...
March 12, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28295547/practitioner-perceptions-of-the-anesthetic-needs-for-magnetic-resonance-imaging-in-pediatric-patients
#16
Glenn E Mann, Adam Canter, Singh Nair, Donna LaMonica, Madelyn Kahana, Jennifer Yoo, Ellise Delphin
There is currently an increasing use of magnetic resonance imaging (MRI) as a diagnostic tool in the pediatric population(1). MRI is often viewed as an ideal diagnostic modality because it does not require exposure to ionizing radiation, provides superior soft tissue image quality compared with computed tomography (CT) and is thus well-suited for neurological, musculoskeletal, cardiac, thoracic, and abdominal studies(2). However, MRIs require patient cooperation and extended time periods of immobility, as the studies are often long, loud, and may induce claustrophobia (2-7)...
March 12, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28295535/longer-and-deeper-cooling-for-hypoxic-ischemic-encephalopathy-in-neonates-does-not-reduce-mortality
#17
Dmitry Dukhovny, John A F Zupancic
No abstract text is available yet for this article.
March 12, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28294428/probiotics-and-antimicrobial-protein-and-peptide-levels-in-preterm-infants
#18
Tobias Strunk, Julie Hibbert, Dorota Doherty, Caitlyn Granland, Stephanie Trend, Karen Simmer, David Burgner, Sanjay Patole, Andrew Currie
AIM: To characterise the secreted and inducible antimicrobial protein and peptide (APP) levels in a prospective cohort of preterm infants (<30 weeks gestational age) with or without Bifidobacterium breve M16V supplementation during the first month of life. METHODS: We analysed serial biosamples of infants who did (n=13) or did not receive (n=62) B. breve (3×10(9) cfu/day). Peripheral blood was obtained on days 1, 14 and 28, and infant stool prior to commencement of probiotic supplementation and on day 21...
March 12, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28294395/child-mental-health-behaviours-that-predicted-the-use-of-health-services-in-wales-from-2011-2014
#19
Ivy Shiue
In 2014 Basa et al (1) reported an alarming increase in paediatric mental disorders in North Wales from 1994-2008 (1). The aim of this study was to investigate the association between mental health and health service use in children, using the annual Welsh Health Survey, and update the evidence. This article is protected by copyright. All rights reserved.
March 12, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28294399/the-impact-of-italian-regionalisation-on-transporting-neonatal-patients-back-from-the-neonatal-intensive-care-unit-to-the-referring-level-two-unit
#20
Carlo Bellini, Luca A Ramenghi
Perinatal regionalisation networks aim to centralise highly skilled care for high-risk neonates and their mothers (1). This study examined how the regional policy in Liguria, Italy, had changed the management of very low birth weight preterm infants. We were particularly keen to look at the impact on back transports, namely transferring patients back to a Level II unit once they did not need to be in the neonatal intensive care unit (NICU) at the IRCCS Istituto Giannina Gaslini, Genoa, Italy. This article is protected by copyright...
March 10, 2017: Acta Paediatrica
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