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Acta Paediatrica

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https://www.readbyqxmd.com/read/28734102/are-electromagnetic-fields-in-incubators-a-risk-factor-for-autism
#1
Carlo V Bellieni, Giuseppe Buonocore
Hugo Lagercrantz recently argued (1) that a possible cause of infantile autism was the unnatural isolation that babies experienced in neonatal incubators. Atypical brain connectivity has been detected in children with autism and it is possible that this may be also due to environmental factors, including the lack of physiological stimuli that is typically found in the incubator environment. We suggest that also another factor may expose babies in incubators to the risk of developing autistic traits and that is the high electromagnetic fields (EMF) produced by the incubator's electric engine...
July 22, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28731539/interleukin-17a-gene-polymorphism-rs2275913-is-associated-with-osteitis-after-the-bacillus-calmette-gu%C3%A3-rin-vaccination
#2
Milla Liehu-Martiskainen, Matti Korppi, Johanna Teräsjärvi, Juho Vuononvirta, Heini Huhtala, Kirsi Nuolivirta, Liisa Kröger, Ville Peltola, Laura Pöyhönen, Qiushui He
AIM: Interleukin-17 (IL-17) appears to promote the host's defense against mycobacterial infections. This study evaluated the association between IL17A gene polymorphism and the risk of Bacillus Calmette-Guérin (BCG) osteitis after newborn vaccination and between IL17A gene polymorphism and IL-17A concentrations in serum. METHODS: IL17A rs2275913 gene polymorphisms and serum IL-17A concentrations were studied in 132 adults aged 21-49 years from across Finland, who had BCG osteitis in infancy after a newborn BCG vaccination...
July 21, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28731511/hypothermia-at-neonatal-intensive-care-unit-admission-was-not-associated-with-respiratory-disease-or-death-in-very-preterm-infants
#3
C F Jensen, F Ebbesen, J P Petersen, A Sellmer, C C Bach, T B Henriksen
AIM: This study investigated the association between hypothermia and respiratory distress syndrome (RDS), bronchopulmonary dysplasia (BPD) or death in very preterm infants admitted to a Danish neonatal intensive care unit (NICU). METHODS: We studied 675 infants born at Aalborg University Hospital before 32 weeks and admitted to the NICU from April 1997 to December 2011. Hypothermia was defined as a core temperature of less than 36.5°C on admission. The primary outcome was severe RDS or death within the first three days of life and the secondary outcome was BPD or death before 36 postmenstrual weeks...
July 21, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28727186/telephone-monitoring-and-home-visits-significantly-improved-the-quality-of-life-treatment-adherence-and-lung-function-in-children-with-cystic-fibrosis
#4
Elisavet-Anna Chrysochoou, Elpis Hatziagorou, Fotis Kirvassilis, John Tsanakas
Cystic Fibrosis (CF) is a chronic and systemic disease with a progressive course. As survival rates continue to improve, there is a growing demand for new therapeutic options that improve treatment adherence, disease management and quality of life (QoL) (1). The aim of this study was to evaluate the safety and effectiveness of a home care programme for children with CF and to assess the value of regular telephone contact with the CF team based at Hippokration Hospital, Thessaloniki, Greece. This article is protected by copyright...
July 20, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28727180/why-was-a-local-anaesthetic-used-before-administering-intranasal-ketamine-for-paediatric-injuries
#5
Sabine Lemoine, Daniel Jost, Kilian Bertho, Jean Pierre Tourtier
We were very interested to read Scheier et al's brief report on the use of intranasal ketamine in their pediatric emergency department, specifically for pain and anxiety in children who had resisted venipuncture or intravenous placement (1). Intravenous access can be difficult for pre-hospital medical teams that are not specialised in paediatric care, namely when children complain of pain from, for example suspected fractures and burns. This article is protected by copyright. All rights reserved.
July 20, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28727173/national-data-study-showed-that-adolescents-living-in-poorer-households-and-with-one-parent-were-more-likely-to-be-bullied
#6
S B Låftman, E Fransson, B Modin, V Östberg
AIM: The aim of this study was to assess whether sociodemographic household characteristics were associated with which Swedish adolescents were more likely to be bullied. METHODS: The data were derived from the Swedish Living Conditions Survey and its child supplements from the survey years 2008-2011. The analyses included information on 3,951 adolescents aged 10-18 years. Exposure to bullying was reported by adolescents and information on sociodemographic household characteristics was reported by parents and obtained from official registers...
July 20, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28722125/a-temperature-gradient-may-support-mother-infant-thermal-identification-and-communication-in-the-breast-crawl-from-birth-to-breastfeeding
#7
Vincenzo Zanardo, Francesca Volpe, Federico de Luca, Gianluca Straface
AIM: The human female's nipple-areolar complex (NAC) is the point of arrival of a natural progression from birth to breastfeeding, linked to functional, chemical and biophysical cues that promote the breast crawl soon after birth. We investigated the thermal gradient generated by the lips of the neonate and warmth of the NAC, which may drive the infant directly to the nipple. METHODS: We prospectively studied 41 full-term singleton infants and their mothers at the Policlinico Abano Terme, Italy, between 1 January to 28 February 2015...
July 19, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28715132/return-of-neonatal-cpap-resistance-the-medijet-device-family-examined-using-in-vitro-flow-simulations
#8
M Falk, S Donaldsson, B Jonsson, T Drevhammar
AIM: Medijet nasal continuous positive airway pressure (CPAP) generators are a family of devices developed from the Benveniste valve. Previous studies have shown that the in-vitro performance of the Medijet disposable generator was similar to the Neopuff resistor system. We hypothesised that resistance would be the main mechanism of CPAP generation in the Medijet disposable generator. METHODS: The in-vitro performance of the Medijet reusable and disposable systems, the Neopuff resistor system and the Benveniste and Infant Flow non-resistor systems were investigated using static and dynamic bench tests...
July 17, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28714101/children-born-extremely-preterm-had-different-sleeping-habits-at-11-years-of-age-and-more-childhood-sleep-problems-than-term-born-children
#9
Kristine Marie Stangenes, Silje Kathrine Fevang, Jacob Grundt, Hilde Mjell Donkor, Trond Markestad, Mari Hysing, Irene Bircow Elgen, Bjørn Bjorvatn
AIM: This study explored whether extremely preterm (EPT) children had different sleep characteristics in childhood than children born at term, and how neurodevelopmental disabilities (NDD) affected sleep in children born EPT. METHODS: A Norwegian national cohort of 231 children born EPT from 1999-2000 and separate study data on 556 children born at term in 2001 were compared. Parental questionnaires mapped the children's current sleep habits at 11 years of age, namely the prevalence of sleep problems throughout childhood until this age and five categories of sleep problems...
July 17, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28712154/a-longitudinal-study-of-cognitive-and-educational-outcomes-of-those-born-small-for-gestational-age
#10
Bing Yu, Anthony Garcy
AIM: This study examined the long-term cognitive and educational outcomes of being born small for gestational age (SGA) and assessed whether the family's attitude towards education modified the effect of being born SGA on educational attainment. METHODS: We used anonymised data on 9,598 individuals from the Stockholm Birth Cohort. This study focused on babies born in 1953 in the Stockholm metropolitan area, who were followed up for 50 years, and included educational data at the age of 13 and 48...
July 16, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28712129/lactobacillus-reuteri-dsm-17938-and-a-placebo-both-significantly-reduced-symptoms-in-children-with-functional-abdominal-pain
#11
M Maragkoudaki, G Chouliaras, R Orel, A Horvath, H Szajewska, A Papadopoulou
AIM: Lactobacillus reuteri is a Gram-positive bacterium that naturally inhabits the human intestinal tract. This study assessed how effectively the probiotic Lactobacilllus reuteri DSM 17938 managed childhood functional abdominal pain (FAP). METHODS: We recruited 54 children with a mean age 9.1±3.8 years, who were diagnosed with FAP in the outpatient clinics of three university hospitals in Greece, Slovenia and Poland, according to the Rome III criteria, from January 2013 to December 2015...
July 16, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28708256/longitudinal-study-shows-that-depression-in-childhood-is-associated-with-a-worse-evolution-of-headaches-in-adolescence
#12
Rémy Amouroux, Céline Rousseau-Salvador, Magdeleine Pillant, Jean-Philippe Antonietti, Barbara Tourniaire, Daniel Annequin
AIM: The aim of this study was to examine the course of headache diagnosis, headache frequency, anxiety, comorbid depressive symptoms and school absenteeism in adolescents with migraine and tension-type headaches five years after baseline. METHODS: We followed a group of 122 children with a mean age of 10.1 (±1.3) years, with headache from a paediatric migraine centre in Paris who had taken part in a previous study from September 2007 to June 2008. This five-year longitudinal study took place in January to June 2012...
July 14, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28708247/adolescents-with-type-1-diabetes-mellitus-and-attention-deficit-hyperactivity-disorder-require-specific-support-from-healthcare-professionals
#13
Ida Lindblad, Ann-Charlotte Engström, Charlotte Nylander, Elisabeth Fernell
AIM: Managing type 1 diabetes mellitus requires efficient cognitive and executive skills and adolescents who have attention-deficit/hyperactivity disorder (ADHD) may face specific challenges. This study explored young people's experiences of diabetes treatment and care. METHOD: In a population-based study, comprising 175 patients aged 5-16 years with type 1 diabetes mellitus in two Swedish counties, we found that eight also met criteria for ADHD. Six of these, aged 14...
July 14, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28695691/neonatal-therapeutic-hypothermia-outside-of-standard-guidelines-a-survey-of-u-s-neonatologists
#14
Jennifer Burnsed, Santina A Zanelli
AIM: Therapeutic hypothermia is standard of care in term infants with moderate-to-severe hypoxic-ischemic encephalopathy (HIE). The goal of this survey was to explore the attitudes of U.S. neonatologists caring for infants with HIE who fall outside of current guidelines. METHOD: Case-based survey administered to members of the Section on Neonatal-Perinatal Medicine of American Academy of Pediatrics. RESULTS: 447 responses were analyzed, i...
July 11, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28695677/combined-genetic-analyses-can-achieve-efficient-diagnostic-yields-for-subjects-with-alagille-syndrome-and-incomplete-alagille-syndrome
#15
Kei Ohashi, Takao Togawa, Tokio Sugiura, Koichi Ito, Takeshi Endo, Kohei Aoyama, Yutaka Negishi, Toyoichiro Kudo, Reiko Ito, Shinji Saitoh
AIM: We evaluated combined genetic analyses with targeted next-generation sequencing (NGS), multiplex ligation probe amplification (MLPA) of Jagged1 (JAG1) genes and microarray comparative genomic hybridisation (CGH) in subjects with Alagille syndrome, incomplete clinical features of Alagille syndrome and biliary atresia. METHODS: Subjects recruited from April 2013 to December 2015 underwent a targeted NGS analysis, including JAG1 and Notch homolog 2 (NOTCH2). If no mutations were detected in JAG1 or NOTCH2, or if copy number variations were suggested by the NGS analysis, we performed an MLPA analysis of JAG1...
July 11, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28695646/the-accuracy-of-the-hemocue-wbc-diff-in-assessing-blood-eosinophils-depends-on-the-clinical-setting-and-medical-condition
#16
Enrico Heffler, Claudia Crimi, Nunzio Crimi
We were very interested to read the paper by Karawajczyk et al on counting white blood cells using a portable, point-of-care device, the HemoCue WBC DIFF (HemoCue AB, Ängelholm, Sweden) (1). The authors concluded that this device was useful and reliable for assessing leucocyte and neutrophil counts, but not eosinophils and monocytes. The study was conducted in a population of children admitted to a paediatric emergency department and a paediatric oncology unit, without any further selection and therefore with a very low probability of eosinophilic diseases...
July 11, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28695642/maternal-intra-partum-antibiotic-treatment-continues-to-exert-a-bactericidal-effect-on-the-umbilical-cord-and-peripheral-venous-blood-of-newborn-infants
#17
C Hershkovich-Shporen, R Bardenstein, I Blickstein, E S Shinwell, O Flidel-Rimon
AIM: It is unclear whether maternal intra-partum antibiotic treatment (IAT) continues to exert a bactericidal effect on common pathogens in neonates. We studied the in vitro bactericidal effect of IAT on the cord and peripheral venous blood of newborn infants. METHODS: Umbilical cord and peripheral venous blood from newborn infants born at Kaplan Medical Center, Israel, from April to October 2014 were studied for serum bactericidal titers against Group B Streptococcus (GBS) and Escherichia coli (E...
July 11, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28695618/quality-predictors-of-parental-satisfaction-after-birth-of-infants-with-life-limiting-conditions
#18
Charlotte Wool, Victoria J Kain, Joana Mendes, Brian S Carter
AIM: This study examines parental satisfaction with care received in the context of a life-limiting fetal diagnosis and subsequent birth. METHODS: Survey methods were utilized to embed the Quality Indicators (QI) and Parental Satisfaction of Perinatal Palliative Care Instrument in a survey: "The Voice of Parents". RESULTS: The web-based survey had a final sample of N=405 parent responders. Overall, parents reported satisfaction with care (80...
July 11, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28692184/traditional-empiric-antibiotic-treatment-is-still-effective-for-neonatal-fever
#19
Maytal Kristal, Vika Dor, Daniel Glikman
Fever may be the only sign of a serious bacterial infection (SBI) in neonates. Ampicillin plus cefotaxime (A+C) and ampicillin plus gentamicin (A+G) are commonly used as empiric therapies for Escherichia coli, Group B Streptococcus (GBS) and Listeria monocytogenes, which are the most likely neonatal SBI pathogens (1). Culture-based screening and prophylaxis has significantly lowered GBS infections and an alarming increase in the antimicrobial resistance rates of Gram-negative bacteria, including cefotaxime and gentamicin resistance, has been reported (1-3)...
July 10, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28692177/age-related-off-label-use-of-nasal-corticosteroids-for-allergies-is-relatively-common-in-finnish-children-with-asthma
#20
Katja Sonninen, Johanna Jyrkkä, Jaana E Martikainen, Kristiina Malmström, Mika J Mäkelä, Kati Sepponen
AIM: Allergies can worsen asthma symptoms and we used national data to identify allergy medication prescribed for Finnish children and adolescents who used asthma medication. METHODS: Register data were available for 13,435 Finnish children aged 0-17 who were entitled to special reimbursement for asthma medication during 2006-2009. Allergy medication purchases were individually analysed two years before and two years after the entitlement for asthma medication reimbursement was granted...
July 10, 2017: Acta Paediatrica
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