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Acta Paediatrica

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https://www.readbyqxmd.com/read/29154388/systematic-review-of-the-effect-of-denosumab-on-children-with-osteogenesis-imperfect-showed-inconsistent-findings
#1
Guowei Li, Yanling Jin, Mitchell A H Levine, Heike Hoyer-Kuhn, Leanne Ward, Jonathan D Adachi
Osteogenesis imperfecta (OI) is a rare, inherited disorder characterised by increased bone fragility, reduced bone mass and often short stature. Most cases are due to mutations in one of the two genes encoding collagen type-1 - COL1A1 and COL1A2 (1) - and the signs and symptoms vary substantially with the disease severity. The risk of fractures is 100 times higher than the general population, even in patients with mild OI. Bisphosphonates are the current standard pharmacotherapy for managing and treating patients with severe OI, but concerns about their long-term safety have been raised (1)...
November 20, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29150869/maternal-mood-disorders-and-lithium-exposure-in-utero-were-not-associated-with-poor-cognitive-development-during-childhood
#2
L Forsberg, M Adler, I Römer Ek, M Ljungdahl, L Navér, L L Gustafsson, G Berglund, A Chotigasatien, U Hammar, B Böhm, K Wide
AIM: This study evaluated whether maternal mood disorders, particularly bipolar disorder, and lithium treatment during pregnancy influenced the neonatal health and cognition of children born from 2006- 2010. METHODS: Our study at Karolinska University Hospital, Stockholm, Sweden, focused on women with and without mood disorders and their children. Information on pharmacotherapy, mental health, delivery and neonatal complications was retrospectively collected from electronic patient records...
November 18, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29150862/randomised-crossover-trial-showed-that-using-breast-milk-or-sucrose-provided-the-same-analgesic-effect-in-preterm-infants-of-at-least-28-weeks
#3
L Collados-Gómez, P Ferrera-Camacho, E Fernandez-Serrano, V Camacho-Vicente, C Flores-Herrero, A M García-Pozo, R Jiménez-García
AIM: Repeated, on-going exposure to pain influences the growth, cognitive and motor functions, behaviour, personality and neurodevelopment of preterm infants. We compared the analgesic effects of expressed breast milk and 24% oral sucrose on preterm neonates during venipuncture. METHODS: This multicentre randomised, non-inferiority, cross-over trial focused on five neonatal university units in Madrid, Spain, from October 2013 to October 2014. It comprised 66 preterm infants born at less than 37 weeks and randomly split into two groups...
November 18, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29131403/does-a-procalcitonin-guided-approach-to-term-and-late-preterm-neonates-with-suspected-early-onset-sepsis-safely-decrease-unnecessary-antibiotic-exposure
#4
https://www.readbyqxmd.com/read/29131402/the-neonatal-transport-index-could-be-used-as-a-reference-tool-for-the-italian-perinatal-care-regionalisation-plan
#5
Carlo Bellini, Luca A Ramenghi
We read with interest the editorial by Hummler on the role of networks in improving perinatal and neonatal care in Acta Paediatrica (1), which dealt with healthcare systems for perinatal care. This included a reference to our paper on this subject, which was also published in the journal (2). There is general agreement that regionalising perinatal care and delivery at high-volume, high-technology hospitals reduces neonatal mortality. This article is protected by copyright. All rights reserved.
November 13, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29131395/do-fidgety-general-movements-predict-cerebral-palsy-and-cognitive-outcome-in-clinical-follow-up-of-very-preterm-infants
#6
Joy Olsen, Peter Marschik, Alicia Spittle
No abstract text is available yet for this article.
November 13, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29131394/shaken-or-stirred-evaluating-the-combination-of-budesonide-surfactant-for-survival-free-of-bronchopulmonary-dysplasia
#7
Kent Willis, Mark Weems
No abstract text is available yet for this article.
November 13, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29131392/virus-detection-in-critically-ill-children-with-acute-respiratory-disease-a-new-profile-in-view-of-new-technology
#8
Atsushi Kawaguchi, Angela Bates, Bonita E Lee, Steven Drews, Daniel Garros
AIM: To describe the epidemiology of critically ill children admitted to a pediatric intensive care unit (PICU) with acute respiratory disease. The association with intubation was analyzed for the three most prevalent viruses and in those with and without viral co-infection. METHODS: Patients admitted to the PICU (2004 - 2014) with acute respiratory disease were included. Analyses were performed utilizing each respiratory viral infection or multiple viral infections as an exposure...
November 13, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29131386/education-school-type-and-screen-time-were-associated-with-overweight-and-obesity-in-2-930-adolescents
#9
Dieter Furthner, Margit Ehrenmueller, Roland Lanzersdorfer, Gerhard Halmerbauer, Klaus Schmitt, Ariane Biebl
AIM: This cross-sectional study analysed the influence of socioeconomic factors on screen time, overweight and obesity. METHODS: We asked adolescents aged 10, 14 and 17 from 10 school types in urban and rural regions in Upper Austria to complete questionnaires from December 2012 to February 2013. Their parents were also asked to complete questionnaires. RESULTS: The questionnaires were completed by 2,930 adolescents and 2,209 parents. Total weekend screen time was significantly associated with a higher body mass index (BMI) in 10-year-old boys (p<0...
November 13, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29121418/the-panorama-of-cerebral-palsy-in-sweden-part-xii-shows-that-patterns-changed-in-the-birth-years-2007-2010
#10
K Himmelmann, P Uvebrant
AIM: This was the 12th population-based study to explore the epidemiology of cerebral palsy (CP) in western Sweden. METHODS: From 2007-2010 there were 104,713 live births in the area. We analysed the birth characteristics, aetiology and neuroimaging findings, calculated the prevalence and compared the results with previous study cohorts. RESULTS: CP was found in 205 children, corresponding to a crude prevalence of 1.96 per 1,000 live births...
November 9, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29119665/adults-who-were-born-preterm-with-a-very-low-birth-weight-reported-a-similar-health-related-quality-of-life-to-their-term-born-peers
#11
Johan Björkqvist, Petteri Hovi, Anu-Katriina Pesonen, Katri Räikkönen, Kati Heinonen, Anna-Liisa Järvenpää, Johan G Eriksson, Sture Andersson, Eero Kajantie
Approximately 1% of European infants are born preterm with a very low birth weight (VLBW) of less than 1,500g and the first babies born at the threshold of viability who received modern neonatal intensive care are now adults. While most live healthy lives, average VLBW adults tend to have more neurodevelopmental disabilities, lower educational achievement and higher rates of chronic conditions (1). Health-related quality of life (HRQoL) is defined as a construct of physical, mental and social wellbeing. This article is protected by copyright...
November 8, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29119603/phototherapy-is-commonly-used-for-neonatal-jaundice-but-greater-control-is-needed-to-avoid-toxicity-in-the-most-vulnerable-infants
#12
Khalaf Mreihil, Jūratė Šaltytė Benth, Hans Jørgen Stensvold, Britt Nakstad, Thor Willy Ruud Hansen
AIM: Limited information is available about how guidelines on phototherapy for neonatal jaundice are applied in practice and toxicity is a concern. We studied the use of phototherapy in relation to birth weight and gestational age (GA) in Norwegian neonatal intensive care units (NICUs). METHODS: The study population was all 5,382 infants admitted to the 21 NICUs in Norway between 1 September 2013 and 31 August 2014. Data were recorded daily in the Norwegian Neonatal Network database and anonymised data on patient characteristics, diagnoses, duration, the ages at the start and discontinuation of phototherapy were analysed...
November 8, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29119594/uniform-national-guidelines-do-not-prevent-wide-variations-in-the-clinical-application-of-phototherapy-for-neonatal-jaundice
#13
Khalaf Mreihil, Britt Nakstad, Hans Jørgen Stensvold, Jūratė Šaltytė Benth, Thor Willy Ruud Hansen
AIM: This study compared the use of phototherapy for neonatal jaundice in all 21 Norwegian neonatal intensive care units (NICUs) from 2013-2014 in order to improve practice. METHODS: Information on all types of phototherapy devices were collected and irradiance was measured from random units at 20cm and 50cm from the light source. We gathered information on local practice rules, including the use of single, double or triple phototherapy, how infants were positioned, the frequency of blood sampling, rules for using reflective surfaces and interrupting phototherapy...
November 8, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29115693/effects-of-fetal-growth-restriction-and-preterm-birth-on-cardiac-morphology-and-function-during-infancy
#14
Emily Cohen, Christie Whatley, Flora Y Wong, Euan M Wallace, Joanne C Mockler, Alexsandria Odoi, Samantha Hollis, Rosemary S C Horne, Stephanie R Yiallourou
AIM: To investigate the effects of fetal growth restriction (FGR) and prematurity on cardiac morphology and function in infancy. We hypothesized that FGR and prematurity would both alter cardiac development. METHODS: Cardiac morphology and function were evaluated in 24 preterm FGR infants (p-FGR) and 23 preterm and 19 term appropriately-grown-for-gestational-age infants (p-AGA and t-AGA, respectively) by conventional echocardiography and Tissue Doppler Imaging. p-FGR and p-AGA infants were studied on postnatal Day One and all groups were studied at one and six months post-term age...
November 8, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29110343/a-possible-way-to-assess-tidal-exhaled-nitric-oxide-in-neonates-and-infants-treated-with-nasal-continuous-positive-airway-pressure
#15
Birgitte Johanne Schmidt, Pauline Schibler Reim, Ole Find Pedersen, Per Albertsen, Gorm Greisen, Inger Merete Jørgensen
The endogenous compound nitric oxide (NO) is released into the airways via inducible NO synthase (1),which has the capacity to produce NO when up-regulated by pro-inflammatory cytokines or exogenous factors, like hypoxia, bacterial toxins and viruses (2). Prematurely born infants are susceptible to various acute and chronic respiratory diseases, such as respiratory distress syndrome and bronchopulmonary dysplasia (BPD). BPD involves a range of lung function abnormalities and increases the risk of re-hospitalisation (3)...
November 6, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29108093/the-self-reported-quality-of-life-of-lithuanian-children-with-asthma-was-comparable-to-western-populations
#16
Vaida Taminskiene, Egle Vaitkaitiene, Algirdas Valiulis, Steve Turner, Adamos Hadjipanayis, Rimantas Stukas, Arunas Valiulis
AIM: Quality of life (QoL) has been widely researched among children with asthma in Western countries, but there is a lack of data from Eastern Europe, where the prevalence is relatively low, but hospital admission rates are higher. We evaluated the overall level and major determinants of QoL in Lithuanian children aged 5-11 years with asthma. METHODS: This study was carried out in six asthma outpatient clinics in the two largest cities of Lithuania from January 2015 to July 2016...
November 6, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29105967/national-study-shows-that-abusive-head-trauma-mortality-in-sweden-was-at-least-10-times-lower-than-in-other-western-countries
#17
Jacob Andersson, Ingemar Thiblin
AIM: The validity of the diagnostic criteria for abusive head trauma (AHT) and its attributes have been widely debated. This national study investigated the possibility of false positive and false negative cases of fatal AHT in Sweden. METHOD: This was a retrospective evaluation of the records of 733 deceased infants up to the age of 365 days who were examined during 1994-2013 at the six forensic medicine departments. All the records were scrutinised for possible cases of AHT...
November 6, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29105835/translating-animal-research-from-the-laboratory-to-the-neonatal-clinical-arena-requires-great-caution
#18
EDITORIAL
Po-Yin Cheung
No abstract text is available yet for this article.
November 6, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29105147/intravenous-paracetamol-was-associated-with-closure-of-the-ductus-arteriosus-in-extremely-premature-infants
#19
S Juujärvi, T Saarela, M Hallman, O Aikio
AIM: Symptomatic patent ductus arteriosus may lead to serious complications in extremely preterm and extremely low birth weight infants and is often resistant to medication. We evaluated early intravenous paracetamol for pain prevention during respiratory therapy, in an attempt to understand the ductal treatment of such infants. METHODS: Our cohort were 295 extremely preterm or extremely low birth weight infants, born at less than 28 weeks or 1,000g, respectively, who were treated in the neonatal intensive care unit of Oulu University Hospital from 2002-2015, before and after intravenous paracetamol was introduced in June 2009...
November 4, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29083092/oxygen-weight-gain-igf-1-and-rop-not-a-straight-forward-equation
#20
EDITORIAL
Brian A Darlow, Gil Binenbaum
No abstract text is available yet for this article.
October 30, 2017: Acta Paediatrica
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