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Acta Paediatrica

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https://www.readbyqxmd.com/read/27896868/crohn-s-disease-should-be-considered-in-children-with-inflammatory-oral-lesions
#1
REVIEW
Anna Skrzat, Dorota Olczak-Kowalczyk, Anna Turska- Szybka
: This systematic review presents the oral manifestations of paediatric Crohn's disease. Our review of 28 papers published from 2000 to 2015 showed that the prevalence of oral manifestations was 10 to 80%. Specific symptoms included mucosal tags, swelling of the lips, cheeks and gingiva and cobblestoning mucosa. Non-specific symptoms included aphthous-like ulcers, angular cheilitis, lip fissuring and gingivitis. CONCLUSION: The oral manifestations of Crohn's disease might precede intestinal inflammation or coincide with it...
November 29, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27889920/neuropeptide-y-receptor-1-is-expressed-by-b-and-t-lymphocytes-and-mast-cells-in-infantile-haemangiomas
#2
Elysia M S Tan, Max G Blackwell, Jonathan C Dunne, Reginald Marsh, Swee T Tan, Tinte Itinteang
AIM: We investigated the expression of neuropeptide Y (NPY), NPY receptor 1 (NPYR1) and NPY receptor 2 (NPYR2) in infantile haemangiomas (IHs). METHODS: Immunohistochemical (IHC) staining was performed on proliferating IHs from six patients aged 4-13 (mean 8.7) months and involuted IHs from six patients aged 5-59 (mean 18.7) years, for the expression of NPY, NPYR1 and NPYR2. Protein and messenger ribonucleic acid expression corresponding to these proteins was investigated by Western blotting and NanoString analysis, respectively...
November 27, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27889912/insulin-like-growth-factor-1-and-metabolic-parameters-are-associated-with-non-alcoholic-fatty-liver-disease-in-obese-children-and-adolescents
#3
Shuang Liang, Xiangdeng Cheng, Yanyan Hu, Ruxin Song, Guimei Li
AIM: Few studies have investigated the relationship between paediatric non-alcoholic fatty liver disease (NAFLD) and insulin like growth factor 1 (IGF-1). This study, carried out from July 2013 to September 2015, aimed to fill the gap and added metabolic parameters to the analysis. METHODS: This was a cross-sectional study of 168 obese children and adolescents (84% male), divided into two groups based on the presence (n=90) or absence (n=78) of NAFLD. All participants underwent clinical examinations, anthropometric and laboratory examinations and liver ultrasonography...
November 27, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27886403/rapid-test-for-lung-maturity-based-on-spectroscopy-of-gastric-aspirate-predicted-respiratory-distress-syndrome-with-high-sensitivity
#4
Henrik Verder, Christian Heiring, Howard Clark, David Sweet, Torben E Jessen, Finn Ebbesen, Lars J Björklund, Bengt Andreasson, Lars Bender, Aksel Bertelsen, Marianne Dahl, Christian Eschen, Jesper Fenger-Grøn, Stine F Hoffmann, Agnar Höskuldsson, Maria Bruusgaard-Mouritsen, Fredrik Lundberg, Anthony D Postle, Peter Schousboe, Peter Schmidt, Hristo Stanchev, Lars Sørensen
AIM: Respiratory distress syndrome (RDS) is a major cause of mortality and morbidity in premature infants. By the time symptoms appear it may already be too late to prevent a severe course, with bronchopulmonary dysplasia or mortality. We aimed to develop a rapid test of lung maturity for targeting surfactant supplementation. METHODS: Concentrations of the most surface-active lung phospholipid dipalmitoylphosphatidylcholine and sphingomyelin in gastric aspirates from premature infants were measured by mass spectrometry and expressed as the lecithin/sphingomyelin ratio (L/S)...
November 25, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27886400/review-of-the-aetiology-diagnostics-and-outcomes-of-childhood-encephalitis-from-1970-2009
#5
Ronny Wickström, Åsa Fowler, Gordana Bogdanovic, Rutger Bennet, Margareta Eriksson
AIM: Encephalitis is a rare, serious condition and anti-viral therapies, increased knowledge of inflammatory pathways and improved diagnostics have increased the therapeutic possibilities. We describe 40 years of childhood encephalitis in Sweden, covering the diagnostics, aetiology and outcomes. METHODS: We reviewed the clinical data that was available for all children discharged from the Karolinska University Hospital in Stockholm following treatment for encephalitis from 1970-2009...
November 25, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27883227/preterm-infants-exhibited-less-pain-during-a-heel-stick-when-they-were-played-the-same-music-their-mothers-listened-to-during-pregnancy
#6
Lina Kurdahi Badr, Taline Demerjian, Tania Daaboul, Hanan Abbas, Mirvat Hasan Zeineddine, Lama Charafeddine
AIM: Playing music during painful procedures has shown inconsistent benefits for preterm infants. This study observed preterm infants during a heel stick procedure to assess whether listening to the music their mothers listened to during pregnancy had any impact on their pain, physiological and behavioural parameters. METHODS: We randomly exposed 42 preterm infants, with a mean gestational age of 31.8 ±2.79 weeks, to the music their mothers listened to during pregnancy, recorded lullabies and no music, before, during and after a heel stick...
November 24, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27883237/iron-concentration-in-breast-milk-normalised-within-one-week-of-a-single-high-dose-infusion-of-iron-in-randomised-controlled-trial
#7
Charlotte Holm, Lars Lykke Thomsen, Astrid Norgaard, Veronika Markova, Kim F Michaelsen, Jens Langhoff-Roos
AIM: We compared the iron concentration in breast milk after a single high-dose of intravenous iron isomaltoside or daily oral iron for postpartum haemorrhage. METHODS: In this randomised controlled trial, the women were allocated a single dose of intravenous 1,200mg iron isomaltoside or oral iron at a mean daily dose of 70.5mg. We included 65 women with sufficient breast milk three days after inclusion - 30 from the intravenous iron group and 35 from the oral iron group - and collected breast milk and maternal blood samples three days and one week after allocation...
November 23, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27880025/attitudes-to-decisions-about-extremely-premature-infants-differed-between-swiss-linguistic-regions-in-population-based-study
#8
Manya J Hendriks, Sabine D Klein, Hans Ulrich Bucher, Ruth Baumann-Hölzle, Jürg C Streuli, Jean-Claude Fauchère
AIM: Studies have provided insights into the different attitudes and values of healthcare professionals and parents toward extreme prematurity. This study explored societal attitudes and values in Switzerland with regard to this patient group. METHODS: A nationwide trilingual telephone survey was conducted in the French, German and Italian speaking regions of Switzerland to explore the general population's attitudes and values with regard to extreme prematurity...
November 23, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27880022/active-commuting-to-school-was-inversely-associated-with-academic-achievement-in-primary-but-not-secondary-school-students
#9
Jose Mora-Gonzalez, Carlos Rodríguez-López, Cristina Cadenas-Sanchez, Manuel Herrador-Colmenero, Irene Esteban-Cornejo, Francisco J Huertas-Delgado, Daniel N Ardoy, Francisco B Ortega, Palma Chillón
AIM: Physical activity has numerous benefits for children when it comes to academic achievements. This study determined whether active commuting - walking or cycling - to school, as a way of increasing total physical activity levels, were associated with academic achievements in students aged 7-18 years. METHODS: A total of 2,138 students participated in the study, which took place in the 2012/2013 academic year in three Spanish cities. We used a self-reported questionnaire to assess how the students travelled to and from school and their final school grades...
November 23, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27859729/secular-changes-in-the-final-height-of-greek-girls-are-leveling-off
#10
Kleanthis Kleanthous, Eleni Dermitzaki, Dimitrios T Papadimitriou, Vassiliki Papaevangelou, Anastasios Papadimitriou
Improvements in socioeconomic conditions in the 20th century resulted in earlier pubertal maturation in children and greater body height during childhood and adulthood (1).However, in some countries the positive secular changes that resulted in greater height, especially in the last decade of the 20th or in the early 21st century (2,3), have come to a halt. We previously reported a secular trend was still taking place in young men in Greece, but at a lower rate than the one recorded in the last quarter of the 20th century (4)...
November 17, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27859634/higher-alcohol-consumption-in-early-pregnancy-or-low-to-moderate-drinking-during-pregnancy-may-affect-children-s-behaviour-and-development-at-1-5-years
#11
Viveka Sundelin-Wahlsten, Gunilla Hallberg, Anders Helander
AIM: It is unclear if low-to-moderate alcohol consumption during pregnancy affects child development. This study examined the effects that a mother's self-reported alcohol consumption had on her pregnancy and her child's birth, behaviour and development. METHODS: We asked 291 Swedish women to report their alcohol consumption before and during pregnancy using the Alcohol Use Disorders Identification Test (AUDIT), provide data on their pregnancy, labour and neonatal period, and complete a child behaviour and development questionnaire when their child was 1...
November 15, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27862264/every-3-versus-every-6-hour-oral-feeding-in-preterm-infants-a-randomized-clinical-trial
#12
Megan M Gray, Barbara Medoff-Cooper, Elizabeth M Enlow, Sagori Mukhopadhyay, Sara B DeMauro
AIM: This trial compares two oral feeding schedules, every 3 hour and every 6 hour oral feeding attempts, to determine which schedule allows for more rapid attainment of full oral feeding in preterm infants. METHODS: Infants born at ≤ 33 weeks gestation were randomly assigned to receive oral feeding every 3 hours or every 6 hours if feeding cues were present. The primary outcome was time to full oral feeding, secondary outcomes include respiratory and apnea rates, growth and length of stay...
November 14, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27862302/scoping-review-shows-wide-variation-in-the-definitions-of-bronchopulmonary-dysplasia-in-preterm-infants-and-calls-for-a-consensus
#13
REVIEW
Delaney Hines, Neena Modi, Shoo K Lee, Tetsuya Isayama, Gunnar Sjörs, Luigi Gagliardi, Liisa Lehtonen, Maximo Vento, Satoshi Kusuda, Dirk Bassler, Rintaro Mori, Brian Reichman, Stellan Håkansson, Brian A Darlow, Mark Adams, Franca Rusconi, Laura San Feliciano, Kei Lui, Naho Morisaki, Natasha Musrap, Prakesh S Shah
: The use of different definitions for bronchopulmonary dysplasia (BPD) has been an on-going challenge. We searched papers published in English from 2010 and 2015 reporting BPD as an outcome, together with studies that compared BPD definitions between 1978 and 2015. We found that the incidence of BPD ranged from 6% to 57%, depending on the definition chosen, and that studies that investigated correlations with long-term pulmonary and, or, neurosensory outcomes reported moderate to low predictive values regardless of the BPD criteria...
November 12, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27862298/two-years-experience-of-using-the-bravo-wireless-oesophageal-ph-monitoring-system-at-a-single-uk-tertiary-centre
#14
Nagendra M Rao, David I Campbell, Prithviraj Rao
AIM: The Bravo wireless pH monitoring system enables oesophageal pH to be monitored in children intolerant to nasal catheters and records measurements over 48 hours. This study aimed to document the minimum child weight that enabled successful capsule placement and any associated complications. We also compared the diagnostic sensitivity of 48 hours versus 24 hours. METHODS: We included 203 consecutive patients (122 male children) with clinically documented or suspected reflux symptoms...
November 12, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27862292/author-s-response-to-suggestion-of-publication-bias-in-a-recent-meta-analysis-on-breastfeeding-and-intelligence-quotient
#15
Bernardo Lessa Horta, Cesar G Victora
No abstract text is available yet for this article.
November 12, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27862266/the-early-postnatal-nutritional-intake-of-preterm-infants-affected-neurodevelopmental-outcomes-differently-in-boys-and-girls-at-24-months
#16
Viola Christmann, Nel Roeleveld, Reina Visser, Anjo J W M Janssen, Jolanda J C M Reuser, Johannes B van Goudoever, Arno F J van Heijst
AIM: his study assessed whether increased amino acid and energy intake in preterm infants during the first week of life was associated with improved neurodevelopment at the corrected age (CA) of 24 months. METHODS: We evaluated preterm infants from two consecutive cohorts in 2004 (Cohort 1) and 2005 (Cohort 2) with different nutritional intakes in The Netherlands. Nutritional intake and growth was recorded until week five and after discharge. Neurodevelopment was determined using the Bayley Scales of Infant Development - Second Edition at a CA of 24 months...
November 12, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27859599/double-blind-placebo-controlled-challenge-showed-that-peanut-oral-immunotherapy-was-effective-for-severe-allergies-without-negative-effects-on-airway-inflammation
#17
Anna Kaarina Kukkonen, Riikka Uotila, Leo Pekka Malmberg, Anna Susanna Pelkonen, Mika Juhani Mäkelä
AIM: This study examined the efficacy and the safety of peanut oral immunotherapy (OIT). METHODS: We recruited 60 patients aged 6-18 years who had a moderate-to-severe reaction to a double-blind placebo-controlled peanut challenge: 39 received OIT during an eight-month build-up phase and maintenance phase and 21 controls avoided peanuts. We measured specific immunoglobulin E and G4 (IgE and IgG4) to peanuts and to Ara h 1, 2, 3, 8, and 9 and monitored adverse events, bronchial hyperresponsiveness (BHR) to methacholine and fractional concentrations of exhaled nitric oxide (FeNO)...
November 12, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27859574/reintroduction-failure-is-common-among-adolescents-after-double-blind-placebo-controlled-food-challenges
#18
Å Strinnholm, A Winberg, L Hedman, E Rönmark, V Lindh
AIM: There has been a lack of research on adolescents who undergo double-blind placebo-controlled food challenges. The aim of this study was to investigate food allergic adolescents' experiences and consequences of double-blind placebo-controlled food challenges. METHODS: This qualitative, descriptive interview study included 17 adolescents aged 14-15 years with total elimination of cows' milk, hens' eggs or cod due to food allergies. The participants, who were initially identified from a large population-based cohort study, were interviewed 18 months after completing their challenges...
November 12, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27862309/study-of-greek-children-and-youths-with-cystic-fibrosis-identifies-immunisation-gaps-and-delays
#19
Helena C Maltezou, Stavros Doudounakis, Maria Lekaditi, Kalliopi Tanou, Panos Katerelos, Maria Theodoridou
AIM: Data about immunisation rates in cystic fibrosis (CF) patients are scarce. We estimated the rates and timeliness of immunisations in CF patients aged 0.55-22 years. METHODS: We studied 122 subjects at a hospital in Greece in 2014. A standard questionnaire was used to collect data and parents' opinions about immunisations. RESULTS: The complete immunisation rates were 92.6% for diphtheria-tetanus-acellular pertussis-inactivated poliomyelitis-Haemophilus influenzae (DTaP-IPV-Hib), 96...
November 10, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27862301/participants-opinions-of-the-limited-impact-of-an-adapted-neonatal-resuscitation-course-in-a-low-resource-setting
#20
Maria Elena Cavicchiolo, Marco Daverio, Paolo Lanzoni, Giulia Segafredo, Damiano Pizzol, Giovanni Putoto, Daniele Trevisanuto
In Mozambique, midwives provide neonatal resuscitation at birth. On January 2014, we held an adapted one-day neonatal resuscitation programme (NRP) course, based on lectures, skill stations and practical scenarios, for the 16 midwives at the Central Hospital of Beira (1), the country's second largest hospital, with about 4,500 deliveries per year. This article is protected by copyright. All rights reserved.
November 10, 2016: Acta Paediatrica
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